how many chromosomes are in the human genome

Human genome The human genome is the complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. Human genomes include both protein-coding DNA genes and noncoding DNA. Haploid human genomes, which are contained in germ cells (the egg and sperm gamete cells created in the meiosis phase of sexual reproduction before fertilization creates a zygote) consist of three billion DNA base pairs, while diploid genomes (found in somatic cells) have twice the DNA content. While there are significant differences among the genomes of human individuals (on the order of 0.1%),[1] these are considerably smaller than the differences between humans and their closest living relatives, the chimpanzees (approximately 4%[2]) and bonobos.


Tirumalai Krishnamacharya Tirumalai Krishnamacharya (November 18, 1888 – February 28, 1989)[1][2] was an Indian yoga teacher, ayurvedic healer and scholar. Often referred to as "the father of modern yoga,"[3][4][5] Krishnamacharya is widely regarded as one of the most influential yoga teachers of the 20th century and is credited with the revival of hatha yoga.[6]


Charlie Day Charles Peckham Day (born February 9, 1976)[1] is an American actor, screenwriter, producer, comedian, and musician. He is best known for playing Charlie Kelly on It's Always Sunny in Philadelphia.[2] On film, he is known for his role as Dale in the films Horrible Bosses (2011) and its 2014 sequel, as well as for his roles in Monsters University (2013), Pacific Rim (2013), The Lego Movie (2014) and Fist Fight (2017).


the cells that surround an axon creating a myelin sheath in the pns are called

Myelin Schwann cells supply the myelin for the peripheral nervous system, whereas oligodendrocytes, specifically of the interfascicular type, myelinate the axons of the central nervous system. Myelin is considered a defining characteristic of the (gnathostome) vertebrates, but myelin-like sheaths have also been seen in some invertebrates, although they are quite different from vertebrate myelin at molecular level. Myelin was discovered in 1854 by Rudolf Virchow.[2]


who sings the chorus on where is the love

Where Is the Love? Shortly after Christmas 2001, will.i.am created a loop and a guitar part that he liked. apl.de.ap and Taboo also heard the track and were able to write similar lyrics over it. Justin Timberlake was introduced to the group by Taboo, and got a chance to hear the track that will.i.am created. Impressed with the music, Timberlake helped write and sing the chorus.


A Beautiful Mind (book) A Beautiful Mind (1998) is a biography of Nobel Prize-winning economist and mathematician John Forbes Nash, Jr. by Sylvia Nasar, professor of journalism at Columbia University. An unauthorized work, it won the National Book Critics Circle Award in 1998 and was nominated for the Pulitzer Prize in biography. It inspired the 2001 film by the same name.


where was the tv show the waltons filmed

The Waltons The town of Walton's Mountain was built in the rear area of the Warner Bros. Studios, but the mountain itself was part of the range opposite Warner studios in Burbank, California. The Waltons' house façade was built in the back of the Warner Brothers lot. After the series concluded, the set was destroyed. For the reunion shows, a replica Waltons' house façade was built on the Here Come the Brides set on the Columbia Ranch studio, now part of the Warner Brothers studios. The Waltons' house is still used as scenery at Warner Brothers. For example, it served as the Dragonfly Inn on The Gilmore Girls.


who coined the phrase i think therefore i am

Cogito, ergo sum Cogito, ergo sum[a] is a Latin philosophical proposition by René Descartes usually translated into English as "I think, therefore I am". The phrase originally appeared in French as je pense, donc je suis in his Discourse on the Method, so as to reach a wider audience than Latin would have allowed.[1] It appeared in Latin in his later Principles of Philosophy. As Descartes explained, "we cannot doubt of our existence while we doubt...." A fuller version, articulated by Antoine Léonard Thomas, aptly captures Descartes’s intent: dubito, ergo cogito, ergo sum ("I doubt, therefore I think, therefore I am").[b][c] The concept is also sometimes known as the cogito.[2]


what was the first year for the chevy duramax

Duramax V8 engine The Duramax is a General Motors diesel engine family for trucks. The 6.6-liter Duramax is produced by DMAX, a joint venture between GM and Isuzu in Moraine, Ohio. The Duramax block and heads are poured at The Defiance GM Powertrain foundry in Defiance, Ohio. This engine was initially installed in 2001 Chevy and GMC trucks, and has been an option since then in pickups, vans, and medium-duty trucks. In 2006, production at Moraine was reportedly limited to approximately 200,000 engines per year.[1] On May 9, 2007, DMAX announced the production of the 1,000,000th Duramax V-8 diesel at its Moraine facility.[1]


what led to the passage by congress of the pure food and drug act

Pure Food and Drug Act The 1906 statute regulated food and drugs moving in interstate commerce and forbade the manufacture, sale, or transportation of poisonous patent medicines.[5] The Act arose due to public education and exposÃ©s from public interest guardians such as Upton Sinclair and Samuel Hopkins Adams, social activist Florence Kelley, researcher Harvey W. Wiley, and President Theodore Roosevelt.


what is the disease that makes you not sleep

Fatal familial insomnia Fatal familial insomnia (FFI) is an extremely rare autosomal dominant inherited prion disease of the brain. It is almost always caused by a mutation to the protein PrPC, but can also develop spontaneously in patients with a non-inherited mutation variant called sporadic fatal insomnia (sFI). FFI has no known cure and involves progressively worsening insomnia, which leads to hallucinations, delirium, confusional states like that of dementia, and eventually, death.[1] The average survival time for patients diagnosed with FFI after the onset of symptoms is 18 months.[1]


Val Kilmer Kilmer attended Berkeley Hall School, a Christian Science school in Los Angeles, until ninth grade.[9] He attended Chatsworth High School with Kevin Spacey and Mare Winningham, and also attended the Hollywood Professional School.[2] He became the youngest person at the time to be accepted into the Juilliard School's Drama Division, where he was a member of Group 10.[10]


Obsessed (2009 film) After repeated attempts to reach Derek on his phone, Sharon finds Derek at the hospital and suspects that he and Lisa had an affair, as Lisa claims. LAPD Detective Monica Reese (Christine Lahti) at first questions Derek's fidelity to Sharon as well, but soon becomes skeptical of Lisa's claims, due to inconsistencies in her story. Sharon, refusing to believe Derek, kicks him out of their house, and he moves into a separate apartment. Months later, Derek and Sharon meet up for dinner and finally reconcile. Meanwhile, Lisa tricks the babysitter Samantha (Scout Taylor-Compton) into letting her in under the pretense of being one of Sharon's friends. When Derek and Sharon return home after dinner, they discover that Lisa had been in the house and seemingly abducted Derek and Sharon's infant son, Kyle (Nathan and Nicolas Myers). Derek goes to his car with the intent to pursue Lisa, only to find the baby is safely sitting in the back seat. He and Sharon immediately take Kyle to the hospital for a check-up. When Derek and Sharon return home from the hospital, they find Lisa has trashed their bedroom and removed Sharon's face from their family portrait. Sharon leaves a threatening voice message on Lisa's phone, and she and Derek set up a home alarm system.


when was the first american girl doll made

American Girl American Girl is an American line of 18-inch (46Â cm) dolls released in 1986 by Pleasant Company. The dolls portray eight- to eleven-year-old girls of a variety of ethnicities. They are sold with accompanying books told from the viewpoint of the girls. Originally the stories focused on various periods of American history, but were expanded in 1995 to include characters and stories from contemporary life. Aside from the original American Girl dolls, the buyer also has the option to purchase dolls that look like them. The options for the line of Truly Me dolls range from eye color, eye shape, skin color, hair texture, and hair length. A variety of related clothing and accessories is also available.


how did florence earn the title birthplace of the renaissance

Italian Renaissance The European Renaissance began in Tuscany (Central Italy), and centred in the city of Florence.[1] Florence, one of the several city-states of the peninsula, rose to economic prominence by providing credit for European monarchs and laying down the groundwork for capitalism and banking.[2] The Renaissance later spread to Venice, heart of a mediterranean empire and in control of the trade routes with the east since the end of the crusades and the voyages of Marco Polo, where the remains of ancient Greek culture were brought together and provided humanist scholars with new texts. Finally the Renaissance had a significant effect on the Papal States and Rome, largely rebuilt by Humanist and Renaissance popes (such as Alexander VI and Julius II), who were frequently involved in Italian politics, in arbitrating disputes between competing colonial powers and in opposing the Reformation.


who sings give me just a little more time

Give Me Just a Little More Time "Give Me Just a Little More Time" is the debut single for Chairmen of the Board, released in 1970 through Capitol Records on Holland–Dozier–Holland's Invictus Records label.


when was the tunnel under the thames built

Thames Tunnel The Thames Tunnel is an underwater tunnel, built beneath the River Thames in London, connecting Rotherhithe and Wapping. It measures 35 feet (11 m) wide by 20 feet (6 m) high and is 1,300 feet (396 m) long, running at a depth of 75 feet (23 m) below the river surface measured at high tide. It was the first tunnel known to have been constructed successfully underneath a navigable river[1] and was built between 1825 and 1843 using Marc Isambard Brunel's and Thomas Cochrane's newly invented tunnelling shield technology, by Brunel and his son Isambard Kingdom Brunel.


arsenal vs man utd head to head premier league

Arsenal F.C.–Manchester United F.C. rivalry Arsenal and Manchester United first played a competitive match in October 1894; as of April 2018, the two clubs have faced each other 228 times in total. United have won 96 to Arsenal's 82, and 50 matches have ended in a draw. Wayne Rooney has scored the most goals in the fixture with 12, while Ryan Giggs has made the highest number of appearances with 50. Several players have featured for both clubs at different stages of their career, including Brian Kidd, Andy Cole, David Platt, Robin van Persie, Danny Welbeck and former manager George Graham.[8]


what was the first valuable use of horses for settlers in the new world

Indian Trade Trade with the Spanish Trading between Spanish settlers and Native Americans was rare and occurred in parts of New Mexico and California. The Spanish mainly intended to spread the Christian faith to Indians and to use them as slaves for work. The most significant effect of trading with the Spanish was the introduction of the horse to the Ute in New Mexico. Gradually, horses bred and their use was adopted across the Great Plains, dramatically altering the lifestyles and customs of many Native American tribes. Many Indians switched from a hunter- gatherer economy to a nomadic lifestyle after they began using horses for transportation. They had a greater range for hunting bison and trading with other tribes.[11]


who wrote the song miracles by jefferson starship

Miracles (Jefferson Starship song) "Miracles" is a song written by Marty Balin and originally recorded by Jefferson Starship, appearing on their 1975 album Red Octopus.[2]


was dr. hook ever on the cover of the rolling stone magazine

The Cover of Rolling Stone As the song was riding high on the charts, the magazine acquiesced to Dr. Hook's request -- sort of. The March 29, 1973 cover of Rolling Stone did indeed feature the band, but in caricature, rather than in a photograph. Also, the group's name was not used; instead the caption read simply, "What's-Their-Names Make the Cover."


who plays poussey in orange is the new black

Samira Wiley Samira Wiley (born April 15, 1987)[1] is an American actress and model. She is best known for playing Poussey Washington in the Netflix series Orange Is the New Black and for playing Moira in the Hulu series The Handmaid's Tale, for which she was nominated for the Primetime Emmy Award for Outstanding Supporting Actress in a Drama Series.


what kind of light source is on a microscope

Fluorescence microscope Fluorescence microscopy requires intense, near-monochromatic, illumination which some widespread light sources, like halogen lamps cannot provide. Four main types of light source are used, including xenon arc lamps or mercury-vapor lamps with an excitation filter, lasers, supercontinuum sources, and high-power LEDs. Lasers are most widely used for more complex fluorescence microscopy techniques like confocal microscopy and total internal reflection fluorescence microscopy while xenon lamps, and mercury lamps, and LEDs with a dichroic excitation filter are commonly used for widefield epifluorescence microscopes. By placing two microlens arrays into the illumination path of a widefield epifluorescence microscope,[6] highly uniform illumination with a coefficient of variation of 1-2% can be achieved.


what show was paint it black the theme song for

Tour of Duty (TV series) The opening theme song was an abbreviated version of The Rolling Stones hit "Paint It, Black" that had featured in the end titles of the 1987 Vietnam War film Full Metal Jacket; this was removed for the US DVD release. The closing consisted of an instrumental, synthesized tune with a distinctive Asian sound mixed in with acoustic guitar; it was performed by Joseph Conlan, and was never released for public consumption other than in the series. That music was used as background music for most of the series. On the US release DVD most of the Vietnam War era popular music was replaced by instrumental bits to cover the blank spots of music.


when did yellowstone national park become a national park

Yellowstone National Park Yellowstone National Park is a national park located in the U.S. states of Wyoming, Montana, and Idaho. It was established by the U.S.Â Congress and signed into law by President Ulysses S. Grant on March 1, 1872.[4][5] Yellowstone was the first National Park in the U.S. and is also widely held to be the first national park in the world.[6] The park is known for its wildlife and its many geothermal features, especially Old Faithful geyser, one of its most popular features.[7] It has many types of ecosystems, but the subalpine forest is the most abundant. It is part of the South Central Rockies forests ecoregion.


where was the 4th pirates of the caribbean filmed

Pirates of the Caribbean: On Stranger Tides Principal photography began on June 14, 2010, in Hawaii.[17][47] Filming was moved to California in August 2010,[48] primarily at the Long Beach shore[33] and a recreation of Whitecap Bay done in the Universal Studios backlot,[17] as the original Hawaiian location on Halona Cove was plagued with strong tides.[22] After a brief shoot in Puerto Rico,[33] with locations in both Palomino Island and the Fort of San Cristóbal in San Juan,[49] production moved to the United Kingdom in September, where principal photography wrapped on November 18 after 106 days of shooting.[17] Locations included Hampton Court Palace in London,[23] Knole House in Kent,[33] and Old Royal Naval College at Greenwich.[50] Interiors were shot at London's Pinewood Studios, and a replica of an 18th-century London street was built on the backlot alongside the soundstages.[33][51] The producers also considered using New Orleans as a location.[52] In October, security was breached at the UK site when a celebrity impersonator gained access to filming at the Old Royal Naval College by dressing up as Captain Jack.[53]


Anna Leonowens Margaret Landon's novel Anna and the King of Siam (1944) provides a fictionalised look at Anna Leonowens's years at the royal court, developing the abolitionist theme that resonated with her American readership.[47] In 1946, Talbot Jennings and Sally Benson adapted it into the screenplay for a dramatic film of the same name, starring Irene Dunne and Rex Harrison. In response, Thai authors Seni and Kukrit Pramoj wrote their own account in 1948 and sent it to American politician and diplomat Abbot Low Moffat (1901â€“1996), who drew on it for his biography Mongkut, the King of Siam (1961). Moffat donated the Pramoj brothers' manuscript to the Library of Congress in 1961.[48][49]


Nothing's Gonna Stop Us Now "Nothing's Gonna Stop Us Now" is a song co-written by Albert Hammond and Diane Warren,[2] recorded by the American rock band Starship in 1986. It is a duet featuring Starship vocalists Grace Slick and Mickey Thomas. Featured as the theme to the romantic comedy film Mannequin,[3][4] it hit No. 1 in the Billboard Hot 100 on April 4, 1987 and reached No. 1 on the UK Singles Chart for four weeks the following month and became the UK's 2nd biggest selling single of 1987. The song also reached the top 10 in six European countries. The single became the first number one single by songwriter Diane Warren.[5] At the time, it made Grace Slick (aged 47) the oldest woman to have a number one single in the United States[6] though the record was later broken by Cher's "Believe" in 1999 (aged 52).


was the battle of gettysburg the bloodiest battle of the civil war

Battle of Gettysburg The Battle of Gettysburg (locally /ˈɡɛtɪsbɜːrɡ/ ( listen), with an /s/ sound)[11] was fought July 1–3, 1863, in and around the town of Gettysburg, Pennsylvania, by Union and Confederate forces during the American Civil War. The battle involved the largest number of casualties of the entire war and is often described as the war's turning point.[12][13] Union Maj. Gen. George Meade's Army of the Potomac defeated attacks by Confederate Gen. Robert E. Lee's Army of Northern Virginia, halting Lee's invasion of the North.


central idea of the poem the world is too much with us

The World Is Too Much with Us "The World Is Too Much with Us" is a sonnet by the English Romantic poet William Wordsworth. In it, Wordsworth criticises the world of the First Industrial Revolution for being absorbed in materialism and distancing itself from nature. Composed circa 1802, the poem was first published in Poems, in Two Volumes (1807). Like most Italian sonnets, its 14 lines are written in iambic pentameter.


what is the population of karachi in 2017

Karachi Karachi is the most linguistically, ethnically, and religiously diverse city in Pakistan.[19] The city is a melting pot of ethno-linguistic groups from throughout Pakistan, as well as migrants from other parts of Asia. The city's inhabitants are referred to by the demonym Karachiite. The 2017 census numerated Karachi's population to be 14,910,352, having grown 2.49% per year since the 1998 census, which had listed Karachi's population at approximately 9.3Â million.[113]


who played the daughter on george lopez show

Masiela Lusha Masiela Lusha (/ˌmɑːsiˈɛlə ˈluːʃə/; born October 23, 1985[1]) is an Albanian-American[2] actress, author, producer and humanitarian. Lusha gained recognition for playing Carmen Lopez on the globally syndicated ABC sitcom George Lopez, a role which earned her two consecutive Young Artist Awards for Leading Young Actress in a Comedy or Drama. After transitioning into film, she starred in Sony Picture's Blood: The Last Vampire. Lusha also starred alongside David Hasselhoff and Ian Ziering in SyFy's television movie Sharknado: The 4th Awakens.[3]


where does a dna strand begin to replicate itself

DNA replication Within eukaryotes, DNA replication is controlled within the context of the cell cycle. As the cell grows and divides, it progresses through stages in the cell cycle; DNA replication takes place during the S phase (synthesis phase). The progress of the eukaryotic cell through the cycle is controlled by cell cycle checkpoints. Progression through checkpoints is controlled through complex interactions between various proteins, including cyclins and cyclin-dependent kinases.[27] Unlike bacteria, eukaryotic DNA replicates in the confines of the nucleus.[28]


where did the expression jump the shark come from

Jumping the shark Popularized by radio personality Jon Hein in the 1990s and early 2000s, the phrase derives from a scene in a fifth-season episode of the sitcom Happy Days in which the character Fonzie jumps over a shark while on water-skis.[2][3][4] This was deemed a ratings ploy, for it was outside the original thrust of the sitcom.


where does the appalachian trail begin and end

Appalachian Trail The Appalachian National Scenic Trail, generally known as the Appalachian Trail or simply the A.T., is a marked hiking trail in the Eastern United States extending between Springer Mountain in Georgia and Mount Katahdin in Maine.[1] The trail is about 2,200 miles (3,500Â km) long, though the exact length changes over time as parts are modified or rerouted.[a] The Appalachian Trail Conservancy reports that the Appalachian Trail is the longest hiking-only trail in the world.[2] More than 2 million people are said to take a hike on part of the trail at least once each year.[3]


who played phoebe on the bold and the beautiful

Phoebe Forrester Phoebe Forrester is a fictional character from the CBS Daytime soap opera The Bold and the Beautiful. The first actress to play the character on a contract basis was Addison Hoover, who joined the show in April 2005 and left just months later. From July 11, 2006 to 2008, Phoebe was played by MacKenzie Mauzy. The character was killed off in 2008. Phoebe Forrester and her twin sister, Steffy (Jacqueline MacInnes Wood), were born in September 1999 to Ridge Forrester (Ronn Moss) and Taylor Hayes (Hunter Tylo). As a result of constant SORASing, Phoebe was seventeen by 2006.


charlie wilson gap band yearning for your love

Yearning for Your Love "Yearning for Your Love" is a quiet storm ballad recorded and released by The Gap Band on Mercury Records. The single was the third release off the band's fifth album, The Gap Band III. Four different singles, each with a different B-side, were released in 1981.


where did i'm forever blowing bubbles come from

I'm Forever Blowing Bubbles The music was written by John Kellette. The lyrics are credited to "Jaan Kenbrovin" â€” actually a collective pseudonym for the writers James Kendis, James Brockman and Nat Vincent, combining the first three letters of each lyricist's last name. The number was debuted in the Broadway musical The Passing Show of 1918, and it was introduced by Helen Carrington.[1]


when was the first wireless tv remote invented

Remote control The first remote intended to control a television was developed by Zenith Radio Corporation in 1950. The remote, called "Lazy Bones", was connected to the television by a wire. A wireless remote control, the "Flashmatic", was developed in 1955 by Eugene Polley. It worked by shining a beam of light onto a photoelectric cell, but the cell did not distinguish between light from the remote and light from other sources. The Flashmatic also had to be pointed very precisely at the receiver in order to work.[8]


Sella turcica The sella turcica (Latin for Turkish seat) is a saddle-shaped depression in the body of the sphenoid bone of the human skull and of the skulls of other hominids including chimpanzees, orangutans, and gorillas. It serves as a cephalometric landmark. The pituitary gland or hypophysis is located within the most inferior aspect of the sella turcica, the hypophyseal fossa.


who retains rights not specifically listed in the constitution

Ninth Amendment to the United States Constitution The Ninth Amendment (Amendment IX) to the United States Constitution addresses rights, retained by the people, that are not specifically enumerated in the Constitution. It is part of the Bill of Rights.


Ed Gein A 16-year-old youth, whose parents were friends of Gein and who attended ball games and movies with him, reported that Gein kept shrunken heads in his house, which Gein had described as relics from the Philippines, sent by a cousin who had served on the islands during World War II.[45] Upon investigation by the police, these were determined to be human facial skins, carefully peeled from corpses and used by Gein as masks.[46]


girl in that's what makes you beautiful video

What Makes You Beautiful The music video for "What Makes You Beautiful" was directed by John Urbano. Filmed over two days in July 2011,[66][67] it premiered on 19 August 2011.[68] On each of the five days preceding the video's premiere, One Direction posted a teaser trailer of the video online. Each teaser showed footage from the video and behind the scenes, and one member of the band announcing how many days were left until the video premiere.[69] The video opens with One Direction spending time on a Malibu, California beach intercut with scenes of them driving an orange campervan. During the second verse, a group of three girls joins the band at the beach; in Styles' bridge solo, he intimately sings to one girl, Madison McMillin,[70] individually. During the final choruses the band and girls are shown sitting around a fire, lighting sparklers and taking photographs.[10] On video sharing website MUZU TV, the video was the fourth most-watched music video of 2011 in the UK.[71] The video won two MTV Video Music Awards for Best Pop Video and Most Share-Worthy Video, and earned the group the award for Best New Artist on 6 September 2012.[72] As of October 2017, the music video has received 890 million Vevo and YouTube views.[73]


where did the saying pull yourself up by your bootstraps come from

Bootstrapping Tall boots may have a tab, loop or handle at the top known as a bootstrap, allowing one to use fingers or a boot hook tool to help pulling the boots on. The saying "to pull oneself up by one's bootstraps"[3] was already in use during the 19th century as an example of an impossible task. The idiom dates at least to 1834, when it appeared in the Workingman's Advocate: "It is conjectured that Mr. Murphee will now be enabled to hand himself over the Cumberland river or a barn yard fence by the straps of his boots."[4] In 1860 it appeared in a comment on philosophy of mind: "The attempt of the mind to analyze itself [is] an effort analogous to one who would lift himself by his own bootstraps."[5] Bootstrap as a metaphor, meaning to better oneself by one's own unaided efforts, was in use in 1922.[6] This metaphor spawned additional metaphors for a series of self-sustaining processes that proceed without external help.[7]


who is the vice president of india who had worked under 3 presidents

Mohammad Hamid Ansari Ansari worked as an ambassador and served as the Vice-Chancellor of the Aligarh Muslim University from 2000 to 2002.[2] Later he was Chairman of the National Commission for Minorities[2] from 2006 to 2007. He was elected as the Vice-President of India on 10 August 2007 and took office on 11 August 2007. He was reelected on 7 August 2012 and was sworn-in by Pranab Mukherjee, the President of India. The oath taking ceremony was conducted at Rashtrapati Bhavan on 11 August 2012.[3] His second term ended in August 2017 since he was not offered another term,he decided not to run for a third term in the 2017 vice-presidential election. Upon the inauguration of Ram Nath Kovind as President of India in 2017, Ansari became the first Indian Vice-President to serve during the terms of three presidents. He was the longest serving chairman of Rajya Sabha.


a command that is recognized and executed by the assembler while the source code is being assembled

Assembly language Assembly language uses a mnemonic to represent each low-level machine instruction or opcode, typically also each architectural register, flag, etc. Many operations require one or more operands in order to form a complete instruction and most assemblers can take expressions of numbers and named constants as well as registers and labels as operands, freeing the programmer from tedious repetitive calculations. Depending on the architecture, these elements may also be combined for specific instructions or addressing modes using offsets or other data as well as fixed addresses. Many assemblers offer additional mechanisms to facilitate program development, to control the assembly process, and to aid debugging.


are specialized cells in the skin which produce melanin

Melanocyte Melanocytes (/məˈlænəˌsaɪt, -noʊ-/ ( listen) or /ˈmɛlənəˌsaɪt, -noʊ-/[1][2]) are melanin-producing neural-crest derived[3] cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea),[4] the inner ear,[5] meninges,[6] bones,[7] and heart.[8] Melanin is the pigment primarily responsible for skin color. Once synthesised, melanin is contained in a special organelle called a melanosome and moved along arm-like structures called dendrites, so as to reach the keratinocytes.


where does winnie the pooh live in the story

Winnie-the-Pooh Many locations in the stories can be linked to real places in and around the forest. As Christopher Milne wrote in his autobiography: "Poohâ€™s forest and Ashdown Forest are identical". For example, the fictional "Hundred Acre Wood" was in reality Five Hundred Acre Wood; Galleon's Leap was inspired by the prominent hilltop of Gill's Lap, while a clump of trees just north of Gill's Lap became Christopher Robin's The Enchanted Place because no-one had ever been able to count whether there were sixty-three or sixty-four trees in the circle.[9]


why do the bare bears stand on each other

We Bare Bears We Bare Bears follows three adoptive bear brothers: Grizzly, Panda and Ice Bear. The bears attempt to integrate with human society, such as by purchasing food, making human companions or trying to become famous on the Internet, although these attempts see the bears struggle to do so due to the civilized nature of humans and their own animal instincts.[2] However, in the end, they figure out that they have each other for support.[3] One notable aspect of the show's humor is the bears' ability to form a "bear stack". As its name shows, the bears stack on top of each other, which serves as their unique way of transportation.[2] Occasionally, the bears share adventures with their friends, such as child prodigy Chloe Park, bigfoot Charlie, internet sensation Nom Nom, park ranger Tabes, and produce saleswoman Lucy. Some flashback episodes chronicle the adventures of the bears as cubs trying to find a home.


when is the last time matchbox 20 toured

Matchbox Twenty The group reunited and began performing during 2007, with the release of their 'retrospective' album Exile on Mainstream, on October 2, 2007. "How Far We've Come" was the first single from the new album, which was followed by the second single, "These Hard Times". "Exile on Mainstream" included four other new songs and a complete collection of all eleven of their previously released singles. The album was also released in the new MVI (Music Video Interactive) format, which included two video interviews discussing the six new songs and eleven greatest hits, plus extras including a photo gallery, U-MYX (to remix "How Far We've Come"), buddy icons and wallpapers. "How Far We've Come" was released on the band's MySpace page in July 2007, with the video released on September 6, 2007. Matchbox Twenty toured during early 2008 with Alanis Morissette and opener Mutemath. The band began their US tour on January 25, 2008, in Hollywood, FL, and concluded in Las Vegas, NV, on March 18, 2008 before heading to Australia and New Zealand, where the Australian band Thirsty Merc was the supporting act. Following Australia, Matchbox Twenty visited the UK for the first time in five years to play six concerts in Cardiff, Wembley, Birmingham, Glasgow, and Manchester. Matchbox Twenty performed at the 2008 NASCAR Sprint Cup award ceremony.


what caused the war between eritrea and ethiopia

Eritrean–Ethiopian War According to a ruling by an international commission in The Hague, Eritrea broke international law and triggered the war by invading Ethiopia.[27] At the end of the war, Ethiopia held all of the disputed territory and had advanced into Eritrea.[28] After the war ended, the Eritreaâ€“Ethiopia Boundary Commission, a body founded by the UN, established that Badme, the disputed territory at the heart of the conflict, belongs to Eritrea.[29] As of 2018[update], Ethiopia still occupies the territory near Badme, including the town of Badme. On 5 June 2018, the ruling coalition of Ethiopia, headed by Prime Minister Abiy Ahmed, agreed to fully implement the peace treaty signed with Eritrea in 2000,[30] with peace declared by both parties in July 2018.[5]


who wrote let's spend the night together

Let's Spend the Night Together "Let's Spend the Night Together" is a song written by Mick Jagger and Keith Richards, and originally released by the Rolling Stones as a double A-sided single together with "Ruby Tuesday" in January 1967.[1] It also appears as the opening track on the American version of their album Between the Buttons. It has been covered by various artists, including David Bowie in 1973.[2]


when was the monopoly of east india company in trade brought under the control of the british crown

East India Company By 1803, at the height of its rule in India, the British East India company had a private army of about 260,000â€”twice the size of the British Army.[5] The company eventually came to rule large areas of India with its private armies, exercising military power and assuming administrative functions.[6] Company rule in India effectively began in 1757 and lasted until 1858, when, following the Indian Rebellion of 1857, the Government of India Act 1858 led to the British Crown's assuming direct control of the Indian subcontinent in the form of the new British Raj.


Jar of Hearts "Jar of Hearts" has been described as an autobiographical song for Perri, recalling an ex-boyfriend who wanted to reconnect after a tough breakup.[8] Seeing writing duties by the song's performer Christina Perri,[clarification needed] additional writing is seen by Drew Lawrence and Barrett Yeretsian; production by the song's writers Barrett Yeretsian and Christina Perri[clarification needed]. "Jar of Hearts" is a rock-oriented tune that is about shunning the continued advances of a former flame who was ungrateful while together, yet now wants to rekindle a failed romance.[9]


what dog breed is duke from secret life of pets

The Secret Life of Pets A Jack Russell Terrier named Max lives with his owner Katie in a Manhattan apartment. While she is at work during the day, he hangs out with other pets in the building: tabby cat Chloe, pug Mel, dachshund Buddy, and budgerigar Sweet Pea. One day, Katie adopts Duke, a large mongrel from the pound, leaving Max jealous because of her divided focus on Duke. Enraged by Max's attitude towards him, Duke tries to abandon Max in an alley, but they are both attacked by cats led by Sphynx cat Ozone who removes both dogs' collars and leaves them to be caught by Animal Control. Duke fears that he will be killed if he goes back to the pound. When Gidget, a white Pomeranian who is (not so) secretly in love with Max, discovers that he is missing, she decides to find him.


who does belle's voice in beauty and the beast

Paige O'Hara Donna Paige Helmintoller, better known as Paige O'Hara (born May 10, 1956),[1] is an American actress, voice actress, singer and painter. O'Hara began her career as a Broadway actress in 1983 when she portrayed Ellie May Chipley in the musical Showboat. In 1991, she made her motion picture debut in Disney's Beauty and the Beast, in which she voiced the film's heroine, Belle. Following the critical and commercial success of Beauty and the Beast, O'Hara reprised her role as Belle in the film's two direct-to-video follow-ups, Beauty and the Beast: The Enchanted Christmas and Belle's Magical World.


how old do you have to be to be prime minister of australia

Age of candidacy In Australia a person must be aged 18 or over to stand for election to public office at federal, state or local government level.


who runs a west coast offense in the nfl

West Coast offense The offense uses a specific naming system, with the routes for [wide receiver]s and tight ends receiving three digit numbers, and routes for backs having unique names. For example, a pass play in 3 digit form might be "Split Right 787 check swing, check V". (see Offensive Nomenclature). This provides an efficient way to communicate many different plays with minimal memorization. Conversely, the Walsh "West Coast offense" could in theory have more freedom, since route combinations are not limited by 0-9 digits, but at the price of much more memorization required by the players.


where does the humerus attach to the scapula

Humerus At the shoulder, the head of the humerus articulates with the glenoid fossa of the scapula. More distally, at the elbow, the capitulum of the humerus articulates with the head of the radius, and the trochlea of the humerus articulates with the trochlear notch of the ulna.


when do lexie and mark get back together season 7

Grey's Anatomy (season 7) Another central story-line in the series is Lexie and Mark. She had decided to give him another chance, but when he tells her Callie is pregnant with her baby, she has had enough. She starts seeing Jackson.


who has most technical fouls in nba history

Technical foul Rasheed Wallace holds the record for the most technical fouls received during one season in the NBA. In the 2000â€“01 season, he received 41 technical fouls in 80 regular season and postseason games played. Wallace also holds the all-time mark for most technical fouls by a player in a career with 317, a record previously held by Dennis Rodman.[7][8]


ranking of st john's medical college bangalore

St. John's Medical College St. John's Medical College was ranked 14th among medical colleges in India in 2017 by India Today,[1] 15th by The Week[3] and 4th in India by Outlook India.[2]


Papa's Got a Brand New Bag "Papa's Got a Brand New Bag" is a song written and recorded by James Brown.[1] Released as a two-part single in 1965, it was Brown's first song to reach the Billboard Hot 100 Top Ten, peaking at number eight, and was a number-one R&B hit, topping the charts for eight weeks.[2][3] It won Brown his first Grammy Award, for Best Rhythm & Blues Recording.[4]


when was the hitchhiker's guide to the galaxy first published

The Hitchhiker's Guide to the Galaxy (novel) The Hitchhiker's Guide to the Galaxy is the first of five books in the Hitchhiker's Guide to the Galaxy comedy science fiction "trilogy" by Douglas Adams. The novel is an adaptation of the first four parts of Adams' radio series of the same name. The novel was first published in London on 12 October 1979.[2] It sold 250,000 copies in the first three months.[3]


what is a good score on the miller analogies test

Miller Analogies Test Tests taken in October 2004 or later have a score range from 200 to 600. The median score is 400, with a standard deviation of 25 points. These scores, based on a normal curve, are known as "scaled" scores. Because of their grounding in this model, scaled MAT scores of 500-600 are extremely rare, as they would be more than four standard deviations above the norm of 400.


who died in real life from sons of anarchy

Johnny Lewis Jonathan Kendrick Lewis (October 29, 1983 â€“ September 26, 2012), also credited as Johnny K. Lewis, was an American film and television actor. Lewis is best known for playing Kip "Half-Sack" Epps in the first two seasons of the FX series Sons of Anarchy. He also appeared in supporting roles in the films Underclassman (2005), Aliens vs. Predator: Requiem (2007), and The Runaways (2010).


who sings the song standing on a corner in winslow arizona

Standin' on the Corner Park Standin' on the Corner Park (opened in 1999 in Winslow, Arizona). It is a public park, commemorating the song "Take It Easy" which was written by Jackson Browne and Glenn Frey and, most famously, recorded by the Eagles. The song includes the verse "Well, I'm a standing on a corner in Winslow, Arizona and such a fine sight to see. It's a girl, my Lord, in a flatbed Ford slowin' down to take a look at me." The park contains a two-story trompe-l'œil mural by John Pugh, and a bronze statue by Ron Adamson[1] of a life-sized man who is standing on a corner with a guitar by his side. The park is surrounded by a wall of bricks, with windows to peer into; each brick has a donor's name on it, and a story by each of the donors describing their fondness for Winslow, Arizona.[2]


when did the coast guard transfer to dhs

United States Coast Guard On 25 November 2002, the Homeland Security Act was signed into law by U.S. President George W. Bush, designating the Coast Guard to be placed under the U.S. Department of Homeland Security. The transfer of administrative control from the U.S. Department of Transportation to the U.S. Department of Homeland Security was completed the following year, on 1 March 2003.[25][26][27]


who has the most all time wins in college football

List of NCAA football teams by wins Measured in total wins, the Michigan Wolverines leads all other football programs across all divisions with 943 wins. The all-time win leaders in the FCS Subdivision and Divisions II and III are the Yale Bulldogs (902 wins), Pittsburg State Gorillas (687 wins), and the Mount Union Purple Raiders (769 wins), respectively.


T helper cell The T helper cells (Th cells) are a type of T cell that play an important role in the immune system, particularly in the adaptive immune system. They help the activity of other immune cells by releasing T cell cytokines. These cells help suppress or regulate immune responses. They are essential in B cell antibody class switching, in the activation and growth of cytotoxic T cells, and in maximizing bactericidal activity of phagocytes such as macrophages.


what is the legislative body of chicago called

Government of Chicago The City Council is the legislative branch and is made up of 50 aldermen, one elected from each ward in the city.[1] The council takes official action through the passage of ordinances and resolutions and approves the city budget.[2] Government priorities and activities are established in a budget ordinance usually adopted each November.


who plays moses wife in the ten commandments

Yvonne De Carlo The first American film star to visit Israel, De Carlo received further recognition as an actress for her work in the British comedies Hotel Sahara (1951) and The Captain's Paradise (1953). Her career reached its peak when eminent producer-director Cecil B. DeMille cast her as Moses' Midianite wife, Sephora, her most prominent role, in his biblical epic The Ten Commandments (1956),[6] which was immensely successful at the box office and remains an annual tradition on television. Her success continued with starring roles in Flame of the Islands (1956), Death of a Scoundrel (1956), Band of Angels (1957), and The Sword and the Cross (1958), in which she portrayed Mary Magdalene. She also accepted supporting roles in McLintock! (1963) and A Global Affair (1964).


when does the regular season for nfl football start

2017 NFL season The 2017 NFL season is the 98th and current season in the history of the National Football League (NFL). The season began on September 7, 2017, with the Kansas City Chiefs defeating the defending Super Bowl LI champion New England Patriots 42â€“27 in the NFL Kickoff Game. The season will conclude with Super Bowl LII, the league's championship game, on February 4, 2018, at U.S. Bank Stadium in Minneapolis, Minnesota.


where does what you talkin bout willis come from

Diff'rent Strokes There were three maids during the sitcom's run: Edna Garrett (Charlotte Rae), Adelaide Brubaker (Nedra Volz), and Pearl Gallagher (Mary Jo Catlett). They lived in the Penthouse Suite at 697 Park Avenue in New York City. As Arnold, Coleman popularized the catchphrase "What'chu talkin' 'bout, Willis?" The ending often varied, depending on whom he was addressing. Early episodes addressed typical issues in a family. Later episodes at times though focused on drug abuse, alcoholism, hitchhiking, and crime, among other issues.


who believed science should be brought to bear in writing history

Thucydides Thucydides (/θjuːˈsɪdɪdiːz/; Greek: Θουκυδίδης Thoukydídēs [tʰuːkydídɛːs]; c. 460 – c. 400 BC) was an Athenian historian and general. His History of the Peloponnesian War recounts the fifth-century BC war between Sparta and Athens until the year 411 BC. Thucydides has been dubbed the father of "scientific history" by those who accept his claims to have applied strict standards of impartiality and evidence-gathering and analysis of cause and effect, without reference to intervention by the deities, as outlined in his introduction to his work.[1][2]


who was the union general who burned a path of destruction through georgia

Sherman's March to the Sea Sherman's March to the Sea, more formally known as the Savannah Campaign, was a military campaign of the American Civil War conducted through Georgia from November 15 to December 21, 1864 by Maj. Gen. William Tecumseh Sherman of the Union Army. The campaign began with Sherman's troops leaving the captured city of Atlanta on November 15 and ended with the capture of the port of Savannah on December 21. His forces destroyed military targets as well as industry, infrastructure, and civilian property and disrupted the Confederacy's economy and its transportation networks. Sherman's bold move of operating deep within enemy territory and without supply lines is considered to be one of the major achievements of the war.


what happened to the mickey hat at hollywood studios

Sorcerer's Hat In October 2014, Disney confirmed that the Sorcerer's Hat would be removed by early 2015.[3] The structure's removal began on January 7, 2015, and was completed on February 25, 2015.[4][5]


Lewis Smith Lake The most popular tourist attraction on Smith lake is the Indian head cliff jump. It's 70 feet ( 21m ) and is located on the south shoreline of Smith lake. It's considered the most dangerous cliff jump located on Smith lake. There have already been two deaths reported where the victims just didn't surface. The bodies were later found.


Benjamin Orr Benjamin Orzechowski (September 8, 1947 â€“ October 3, 2000), known professionally as Benjamin Orr, was an American musician best known as a singer, bassist and co-founder of the rock band the Cars. He sang lead vocals on several of their best known songs, including "Just What I Needed", "Let's Go" and "Drive". He also scored a moderate solo hit with "Stay the Night." Orr was posthumously inducted into the Rock and Roll Hall of Fame as a member of the Cars in 2018.[1]


Under the Dome (novel) The semi-organized resistance flees to the abandoned farm, where multiple people touch the strange object and experience visions. They not only conclude that the device was put in place by extraterrestrial "leatherheads" (so named for their appearance), but that specifically they are juveniles who have set up the Dome as a cruel form of entertainment, a sort of ant farm used to capture sentient beings and allow their captors to view everything that happens to them.


the boy in the striped pyjamas brunos friends

The Boy in the Striped Pyjamas Bruno is a 9-year-old boy growing up during World War II in Berlin. He lives with his parents, his 12-year-old sister Gretel and maids, one of whom is called Maria. After a visit by Adolf Hitler, Bruno's father is promoted to Commandant, and the family has to move to "Out-With" because of the orders of "The Fury" (Bruno's naïve interpretation of the word 'Führer'). Bruno is initially upset about moving to Out-With (in actuality, Auschwitz)[4] and leaving his friends, Daniel, Karl, and Martin. From the house at Out-With, Bruno sees a camp in which the prisoners wear striped pyjamas. One day, Bruno decides to explore the strange wire fence. As he walks along the fence, he meets a Jewish boy named Shmuel, who he learns shares his birthday. Shmuel says that his father, grandfather, and brother are with him on this side of the fence, but he is separated from his mother. Bruno and Shmuel talk and become very good friends, although Bruno still does not understand very much about Shmuel and his side of the fence. Nearly every day, unless it's raining, Bruno goes to see Shmuel and sneaks him food. As the meetings go on, and Shmuel gets more and more skinny, Bruno's naïveté is proved, as he never realizes he is living beside a death camp.


The Crown (TV series) The first season was released on Netflix on November 4, 2016, with the second released on December 8, 2017. The series has been renewed for a third and fourth season, with the third intended to be released in 2019. The Crown was praised for its acting, directing, writing, cinematography, production values, and the relatively accurate historical account of Queen Elizabeth's reign. It has received several accolades, including winning Best Actress and Best Actor at the 23rd Screen Actors Guild Awards for Foy and Lithgow, respectively, in addition to receiving a total of 26 nominations for its first two seasons at the Primetime Emmy Awards, including twice for Outstanding Drama Series.[5]


east african rift is what type of plate boundary

East African Rift The rift is a narrow zone that is a developing divergent tectonic plate boundary, where the African Plate is in the process of splitting into two tectonic plates, called the Somali Plate and the Nubian Plate, at a rate of 6–7 mm (0.24–0.28 in) annually.[2] As extension continues, lithospheric rupture will occur within 10 million years, the Somali plate will break off, and a new ocean basin will form.


who wrote the majority opinion in mcdonald v. chicago

McDonald v. City of Chicago Writing for the majority, Justice Alito held that the Due Process Clause of the Fourteenth Amendment incorporates the Second Amendment right recognized in Heller.[22] Writing a concurring opinion, Justice Thomas reached the same conclusion regarding the incorporation issue on different grounds: Privileges or Immunities Clause of the Fourteenth Amendment.[23] The majority decision also reaffirmed that certain firearms restrictions mentioned in District of Columbia v. Heller are assumed permissible and not directly dealt with in this case.[24] Such restrictions include those to "prohibit...the possession of firearms by felons or mentally ill" and "laws forbidding the carrying of firearms in sensitive places such as schools and government buildings, or laws imposing conditions and qualifications on the commercial sale of arms".[24]


a male voice type between tenor and bass

Voice type Baritone range: The baritone voice is the middle-range voice type for males; it lies between the bass and tenor ranges, overlapping both of them. The typical baritone range is from A2 (the second A below middle C) to A4 (the A above middle C). A baritone's range might extend down to F2 or up to C5. The baritone voice type is the most common male voice.[5]


where did the devil is in the details come from

The devil is in the detail The idiom, "God is in the detail" has been attributed to a number of different individuals, most notably to German-born architect Ludwig Mies van der Rohe (1886–1969) by The New York Times in Mies's 1969 obituary; however, it is generally accepted not to have originated with him. The expression also appears to have been a favorite of German art historian Aby Warburg (1866–1929), though Warburg's biographer, E.M. Gombrich, is likewise uncertain if it originated with Warburg. An earlier form, "Le bon Dieu est dans le détail" ("the good God is in the detail") is generally attributed to Gustave Flaubert (1821–1880).[1] Bartlett's Familiar Quotations lists the saying's author as anonymous.[3] The phrase is attested in 1965;[4] in 1969, it is referred to as an existing proverb.[5]


when did the founding fathers write the constitution

Founding Fathers of the United States The newly founded country of the United States had to create a new government to replace the British Parliament. The U.S. adopted the Articles of Confederation, a declaration that established a national government with a one-house legislature. Its ratification by all thirteen colonies gave the second Congress a new name: the Congress of the Confederation, which met from 1781 to 1789.[16] The Constitutional Convention took place during the summer of 1787, in Philadelphia.[17] Although the Convention was called to revise the Articles of Confederation, the intention from the outset for some including James Madison and Alexander Hamilton was to create a new frame of government rather than amending the existing one. The delegates elected George Washington to preside over the Convention. The result of the Convention was the United States Constitution and the replacement of the Continental Congress with the United States Congress.


who is the actor that played apollo creed

Carl Weathers Carl Weathers (born January 14, 1948) is an American actor and former professional football player. He is best known for portraying Apollo Creed in the Rocky series of films, George Dillon in Predator, Chubbs Peterson in Happy Gilmore and Little Nicky, and a fictionalized version of himself on the comedy series Arrested Development. As a football player, Weathers played for the Oakland Raiders of the National Football League and the B.C. Lions of the Canadian Football League.


Dwarf planet The IAU has recognized five bodies as dwarf planets since 2008: Ceres, Pluto, Eris, Haumea, and Makemake.[48] Ceres and Pluto are known to be dwarf planets through direct observation.[49] Eris is recognized as a dwarf planet because it is more massive than Pluto (measurements by New Horizons indicate that Pluto's diameter is larger than that of Eris), whereas Haumea and Makemake qualify based on their absolute magnitudes.[9][38] In relative distance from the Sun, the five are:


i am very glad as i'm finally returning back home

Eduard Khil Eduard Anatolyevich Khil (Russian: Эдуа́рд Анато́льевич Хиль, IPA: [ɨdʊˈart ɐnɐˈtolʲjɪvʲɪt͡ɕ ˈxʲilʲ] (often anglicized as Edward Hill); 4 September 1934—4 June 2012) was a Soviet-Russian baritone singer and a recipient of the People's Artist Award of the Russian SFSR. Khil became known to international audiences in 2010, when a 1976 recording of him singing a non-lexical vocable version of the song "I Am Very Glad, as I'm Finally Returning Back Home" (Russian: Я о́чень рад, ведь я, наконе́ц, возвраща́юсь домо́й, tr. Ya ochen rad, ved ya, nakonets, vozvrashchajus domoy) became an Internet meme, often referred to as "Trololol" or "Trololo",[1] as an onomatopoeia of the song, or as the "Russian Rickroll", and as such, the song was commonly associated with Internet trolling.


who played raymond's brother in everybody loves raymond

Brad Garrett After achieving a strong measure of success with stand-up comedy, Garrett decided to change gears and try his luck with performing on TV. From 1985–1986, he was the voice of Hulk Hogan (in a voice similar to Rodney Dangerfield) for the cartoon series Hulk Hogan's Rock 'n Wrestling, He was featured on Family Feud during Ray Combs's tenure in a "Funny Men vs. Funny Women Week" during November sweeps. He also appeared for a week on the game show Super Password in 1987. He also appeared on Hollywood Squares including a memorable moment when he impersonated Bill Cosby during a question about Jell-o. He then appeared in the short-lived summer comedy First Impressions (CBS, 1988), in which he was a divorced father who makes a living doing impressions, in a one-time spot as a bank loan officer on Roseanne (ABC), and The Pursuit of Happiness (NBC, 1995–96), in which he was the hero's gay best friend. Though prior to these roles, Garrett had also had a minor part on Transformers, voicing the Decepticon base Trypticon in season three and as an ill-fated thug in Suicide Kings. He soon won the role of Ray Romano's brother Robert Barone on the long-running family-oriented comedy hit Everybody Loves Raymond. Garrett has also made an appearance on The Fresh Prince of Bel-Air playing a hitman who attempts to kill Will Smith's character.


america's next top model girl from somalia

Fatima Siad Fatima Siad (Somali: Fadumo Siyaad, Arabic: فاطمة سياد) (born December 17, 1986) is a Somali-American fashion model.[2] Raised in Boston, Massachusetts, she placed third on America's Next Top Model, Cycle 10.


where does transcription begin and what are the steps of transition

Eukaryotic transcription The initiation of gene transcription in eukaryotes occurs in specific steps.[1] First, an RNA polymerase along with general transcription factors binds to the promoter region of the gene to form a closed complex called the preinitiation complex. The subsequent transition of the complex from the closed state to the open state results in the melting or separation of the two DNA strands and the positioning of the template strand to the active site of the RNA polymerase. Without the need of a primer, RNA polymerase can initiate the synthesis of a new RNA chain using the template DNA strand to guide ribonucleotide selection and polymerization chemistry.[1] However, many of the initiated syntheses are aborted before the transcripts reach a significant length (~10 nucleotides). During these abortive cycles, the polymerase keeps making and releasing short transcripts until it is able to produce a transcript that surpasses ten nucleotides in length. Once this threshold is attained, RNA polymerase passes the promoter and transcription proceeds to the elongation phase.[1]


The Voice (U.S. TV series) The Voice is an American reality television singing competition broadcast on NBC. Based on the original The Voice of Holland, the concept of the series is to find currently unsigned singing talent (solo or duets, professional and amateur) contested by aspiring singers, age 15 or over (reduced to 13 since season 12),[2] drawn from public auditions. The winner is determined by television viewers voting by telephone, internet, SMS text, and iTunes Store purchases of the audio-recorded artists' vocal performances. They receive US$100,000 and a record deal with Universal Music Group for winning the competition. The winners of the thirteen seasons have been: Javier Colon, Jermaine Paul, Cassadee Pope, Danielle Bradbery, Tessanne Chin, Josh Kaufman, Craig Wayne Boyd, Sawyer Fredericks, Jordan Smith, Alisan Porter, Sundance Head, Chris Blue and Chloe Kohanski.


when was the last time the us constitution was amended

List of amendments to the United States Constitution Thirty-three amendments to the United States Constitution have been proposed by the United States Congress and sent to the states for ratification since the Constitution was put into operation on March 4, 1789. Twenty-seven of these, having been ratified by the requisite number of states, are part of the Constitution. The first ten amendments were adopted and ratified simultaneously and are known collectively as the Bill of Rights. Six amendments adopted by Congress and sent to the states have not been ratified by the required number of states. Four of these amendments are still technically open and pending, one is closed and has failed by its own terms, and one is closed and has failed by the terms of the resolution proposing it.


who is the highest paid major league baseball player

List of highest paid Major League Baseball players The highest-paid player in Major League Baseball (MLB) from the 2018 Major League Baseball season is Los Angeles Dodgers' pitcher Clayton Kershaw with an annual salary of $34,000,000 on a 7 year contract for $215,000,000. MLB does not have a hard salary cap, instead employing a luxury tax which applies to teams whose total payroll exceeds certain set thresholds for a given season.[1][2] Free agency did not exist in MLB prior to the end of the reserve clause in the 1970s, allowing owners before that time to wholly dictate the terms of player negotiations and resulting in significantly lower salaries. Babe Ruth, widely regarded as one of the greatest baseball players ever, earned an estimated $910,696 ($14,654,832 inflation-adjusted from 1931 dollars) over his entire playing career.[3] When asked whether he thought he deserved to earn $80,000 a year ($1,171,952 inflation-adjusted), while the president, Herbert Hoover, had a $75,000 salary, Ruth famously remarked, "What the hell has Hoover got to do with it? Besides, I had a better year than he did."[4][5]


Booting Boot is short for bootstrap[1][2] or bootstrap load and derives from the phrase to pull oneself up by one's bootstraps.[3][citation needed]The usage calls attention to the requirement that, if most software is loaded onto a computer by other software already running on the computer, some mechanism must exist to load the initial software onto the computer.[4] Early computers used a variety of ad-hoc methods to get a small program into memory to solve this problem. The invention of read-only memory (ROM) of various types solved this paradox by allowing computers to be shipped with a start up program that could not be erased. Growth in the capacity of ROM has allowed ever more elaborate start up procedures to be implemented.


United States passport The machine-readable zone is present at the bottom of the page and contains P<USA[SURNAME]<<[GIVEN NAME(S)]<<<<<<<<<< in the first line and [PASSPORT NO. + 1 DIGIT]USA[DATE OF BIRTH + 1 DIGIT + SEX + DATE OF EXPIRATION + 10 DIGITS]<[6 DIGITS] in the second line. Both lines contain 44 characters in a fixed-width all-caps font, with the top line ending with enough left angle brackets to fill the 44 character limit.


what sports did they do in ancient greece olympics

Ancient Olympic Games The games started in Olympia, Greece, in a sanctuary site for the Greek deities near the towns of Elis and Pisa (both in Elis on the peninsula of Peloponnesos). The first games began as an annual foot race of young women in competition for the position of the priestess for the goddess, Hera,[24] and a second race was instituted for a consort for the priestess who would participate in the religious traditions at the temple.[25]


when was the last time they killed kenny

Kenny McCormick The first explanation given for Kenny's deaths and reappearances was given in "Cartman Joins NAMBLA", wherein the McCormicks have a baby exactly like Kenny, including the characteristic orange parka, shortly after the former Kenny dies. Mr. McCormick exclaims, "God, this must be the fiftieth time this has happened", to which Mrs. McCormick quickly replies, "Fifty-second". This explanation is expanded upon in the Season 14 episodes "Coon 2: Hindsight", "Mysterion Rises" and "Coon vs. Coon and Friends", in which Kenny, while playing superheroes with his friends, claims his "super power" is immortality. He actually dies several times during these episodes—even committing suicide more than once—reawakening alive and unharmed in his bed each time. He is frustrated and angry that no one can remember him dying every time he regenerates, and longs to know the source of his power, which he views as a curse. Unbeknownst to him, his parents were previously connected to a Cthulhu-worshipping death cult. After Kenny shoots himself the second time, Mrs. McCormick awakes with a scream, shrieks "It's happening again!", and minutes later, is shown gently placing a newborn Kenny in his bed. "We should never have gone to that stupid cult meeting," she grouses as she and her husband return to bed.


analyzing and interpreting reports is what aspect of accounting

Financial statement analysis Financial statement analysis (or financial analysis) is the process of reviewing and analyzing a company's financial statements to make better economic decisions. These statements include the income statement, balance sheet, statement of cash flows, and a statement of changes in equity. Financial statement analysis is a method or process involving specific techniques for evaluating risks, performance, financial health, and future prospects of an organization.[1]


when did they stop using leather helmets in football

Football helmet In 1939, the Riddell Company of Chicago, Illinois started manufacturing plastic helmets because it felt that plastic helmets would be safer than those made of leather. Plastic was found to be more effective because it held its shape when full collision contact occurred on a play. These helmets were also much more comfortable and had more padding to cushion the head in an impact. Included with the plastic helmet came plastic face mask, which allowed the helmet to protect the entire head. By the mid-1940s, helmets were required in the NFL. They were still made of leather, but with improved manufacturing techniques had assumed their more familiar spherical shape. The NFL initially allowed either plastic or leather helmets, but in 1948 the league outlawed the plastic helmet, considering the hard-plastic material to be an injury risk. The NFL repealed this rule in 1949, and by 1950, the plastic helmet had become universal in that league.[2]


where was the us open tennis held before flushing meadows

US Open (tennis) In 1978, the tournament moved from the West Side Tennis Club to the larger and newly constructed USTA National Tennis Center in Flushing Meadows, Queens, three miles to the north. The tournament's court surface also switched from clay to hard. Jimmy Connors is the only individual to have won US Open singles titles on three surfaces (grass, clay, and hard), while Chris Evert is the only woman to win US Open singles titles on two surfaces (clay and hard).[3]


Moto Z In the United States, Moto Z is carrier-exclusive to Verizon Wireless under the name Moto Z Droid Edition, as part of the Droid line of smartphones that are exclusively manufactured[2] by Motorola.[3] It was released direct-to-consumer as an unlocked device in September 2016.[4]


how many signs do you have to find in slender man

Slender Rising The signs are randomly scattered across the map. Ghostly whisper sound effects help the player find them, as well as a red arrow if the compass option is selected. The Slender Man stalks the player around the map, and can teleport closer to the player, but they must avoid looking at the enemy. When the player sees the Slender Man, they must quickly look away or they will be killed (and lose the round). Two gameplay options are available: an infinite mode where the player must find as many signs as possible before they are killed by the enemy; or a limited mode where they must collect seven signs, whilst Slender Man becomes increasingly more aggressive as they progress. Difficulty can also be selected.


Mass-to-charge ratio Some fields use the charge-to-mass ratio (Q/m) instead, which is the multiplicative inverse of the mass-to-charge ratio. The 2014 CODATA recommended value for an electron is  e⁄me = - 7011175882002400000♠1.758820024(11)×1011 C/kg.[2]


what is the function of the chordea tendineae

Chordae tendineae When the ventricles of the heart contract in ventricular systole, the increased blood pressures in both chambers push the AV valves to close simultaneously, preventing backflow of blood into the atria. Since the blood pressure in atria is much lower than that in the ventricles, the flaps attempt to evert to the low pressure regions. The chordae tendineae prevent the eversion, prolapse, by becoming tense thus pulling the flaps, holding them in closed position.[1]


who played worf's son on star trek the next generation

Brian Bonsall Brian Eric Bonsall (born December 3, 1981) is an American rock musician, singer, guitarist and former child actor. He is perhaps best known for his roles as Andrew "Andy" Keaton, the youngest child on the NBC sitcom Family Ties from 1986 until 1989, and Alexander Rozhenko, the son of Worf and K'ehleyr, on Star Trek: The Next Generation from 1992 to 1994.


who is currently the longest serving supreme court justice

List of United States Supreme Court Justices by time in office A total of 113 Justices have served on the Supreme Court of the United States, the highest judicial body in the United States. Justices have life tenure, and so they serve until they die in office, resign or retire, or are impeached and removed from office (which has never happened; the one impeached Justice was acquitted). The longest-serving member of the current court is Associate Justice Anthony Kennedy, with a term to date of 7004108520000000000â™ 10,852 days (29 years). For the 104 non-incumbent justices, the mean length of service was 6,112 days (16.7 years) with a standard deviation of 3,620 days (9.9 years). The median length of service was 5,740 days (15.7 years). Their period of service ranges from William O. Douglas's 13,358 days (36 years) on the Court to the 163-day tenure of Thomas Johnson.


what is the legal age to carry a gun in texas

Gun laws in Texas The handgun licensing law sets out the eligibility criteria that must be met. For example, an applicant must be eligible to purchase a handgun under the State and Federal laws (including an age restriction of 21), however an exception is granted to active members of the military who are age 18 and over. Additionally, a number of factors may make a person ineligible (temporarily or permanently) to obtain a license, including:


The Bells of St. Mary's They put their hopes in Horace P. Bogardus (Henry Travers), a businessman who has built a modern building next door to the school which they hope he will donate to them. Father O'Malley and the dedicated but stubborn Sister Superior, Mary Benedict (Ingrid Bergman), both wish to save the school, but their different views and methods often lead to disagreements. One disagreement involves a student (Richard Tyler) who is being bullied by another. A more serious one regards the promotion of an eighth-grade student, Patsy (Joan Carroll), whom the parish has taken in while her mother (Martha Sleeper) attempts to get back on her feet.


what is the enzyme in the large intestine

Large intestine The bacteria break down some of the fiber for their own nourishment and create acetate, propionate, and butyrate as waste products, which in turn are used by the cell lining of the colon for nourishment.[32] No protein is made available. In humans, perhaps 10% of the undigested carbohydrate thus becomes available, though this may vary with diet;[33] in other animals, including other apes and primates, who have proportionally larger colons, more is made available, thus permitting a higher portion of plant material in the diet. The large intestine[34] produces no digestive enzymes â€” chemical digestion is completed in the small intestine before the chyme reaches the large intestine. The pH in the colon varies between 5.5 and 7 (slightly acidic to neutral).[35]


why do organisations develop and adopt policies for the acceptable use of ict

Acceptable use policy An acceptable use policy (AUP), acceptable usage policy or fair use policy, is a set of rules applied by the owner, creator or administrator of a network, website, or service, that restrict the ways in which the network, website or system may be used and sets guidelines as to how it should be used. AUP documents are written for corporations,[1] businesses, universities,[2] schools,[3] internet service providers (ISPs),[4] and website owners,[5] often to reduce the potential for legal action that may be taken by a user, and often with little prospect of enforcement.


who is the well known photographer of telangana

Bandi Rajan Babu Bandi Rajan Babu was born at Korutla, in the Karimnagar district of Telangana. Starting his career as a lecturer at JNTU Fine Arts College, he went on to establish his own school and master the craft of â€˜pictorial photography'. He was a Fellow of the Royal Photographic Society of Great Britain, an Associate of the Federation of International Photographic Art, France, and an Honorary Fellow of the AP State Akademi of Photography.


do treaties have to comply with the constitution

Treaty Clause Additionally, an international accord that is inconsistent with the U.S. Constitution is void under domestic U.S. law, the same as any other federal law in conflict with the Constitution. This principle was most clearly established in the case of Reid v. Covert.[9] The Supreme Court could rule an Article II treaty provision to be unconstitutional and void under domestic law, although it has not yet done so.


Larry Silverstein Silverstein was born in Brooklyn, and became involved in real estate, together with his father, establishing Silverstein Properties. Silverstein separated from his business partner, Bernard Mendik, in 1977, and bought a number of large office buildings in Midtown and Lower Manhattan in the late 1970s. In 1980, Silverstein won a bid from the Port Authority of New York and New Jersey to construct 7 World Trade Center, to the north of the World Trade Center site. Silverstein was interested in acquiring the entire World Trade Center complex, and put in a bid when the Port Authority put it up for lease in 2000. Silverstein won the bid when a deal between the initial winner and the Port Authority fell through, and he signed the lease on July 24, 2001.


Thelma & Louise Thelma and Louise are finally cornered by the authorities only one hundred yards from the edge of the Grand Canyon. Hal arrives on the scene, but he is refused the chance to make one last attempt to talk the women into surrendering. Rather than be captured and spend the rest of their lives in jail, Thelma proposes that they "keep going". Louise asks Thelma if she is certain, and Thelma says yes. They kiss, then Louise steps on the accelerator, and they ride the car over the cliff to their deaths.


is there an in and out in las vegas airport

McCarran International Airport Terminal 1 and Terminal 3 have their own parking garages.[134][135] Each also has its own economy lot, which provides lower parking rates,[136][137] and a separate lot for oversize vehicles.[138][139] Complimentary shuttle transportation is provided between the terminals and the remote Terminal 1 economy and oversize vehicle lots. In March 2016, the airport opened a cellphone lot, which provides free parking to people waiting for passengers.[140]


where does the bbc get its weather forecast from

BBC Weather On 23 August 2015, the BBC announced that the Met Office will lose its contract as the BBC is legally obliged to ensure that licence fee payers get the best value for money. MeteoGroup is due to take over on 31 March 2018,[1][2] although the on air presenting team is not expected to change, and Met Office severe weather warnings will continue to be used by BBC Weather.[3]


brown and white bird with black rings around neck

Killdeer The killdeer is a large plover, with adults ranging in length from 20 to 28 centimetres (7.9 to 11.0 in), having a wingspan between about 59 and 63 centimetres (23 and 25 in), and usually being between 72 and 121 grams (2.5 and 4.3 oz) in weight.[3] It has a short, thick, and dark bill, flesh-coloured legs, and a red eye ring.[8] Its upperparts are mostly brown with rufous fringes,[3] its cap, back, and wings being the former colour. It has a white forehead and a white stripe behind the eye, and its lores and the upper borders to the white forehead are black. The killdeer also has a white collar that is black on its upper border. The rest of the face is brown. The breast and belly are white, with the exception of two black breast bands. The rump is red, and the tail is mostly brown. The latter also has a black subterminal band, a white terminal band, and barred white feathers on the outer portion of the tail. In flight, a white wing stripe at the base of the flight feathers is visible.[8]


the process of peristalsis is best described as the

Peristalsis Peristalsis is a radially symmetrical contraction and relaxation of muscles that propagates in a wave down a tube, in an anterograde direction.


Joey Potter "Joey Potter is a headstrong, vibrant, wily, sultry, and determined go-getter. And yet, in a gloriously contradictory manner, in spite of her tough-as-nails exterior demeanor, Joey's also a frail, sometimes uncertain, emotionally sensitive, in-need-of-love person", said the show's official book.[5] Joey, named for Jo in Little Women, for years had been climbing in Dawson's bedroom window and platonically sharing his bed. Joey's mother had died from cancer when Joey was thirteen and her father, Mike (Gareth Williams), was in prison for "conspiracy to traffic in marijuana in excess of 10,000 pounds." Her harried, unmarried, and very pregnant sister, Bessie (Nina Repeta), about ten years older than Joey,[n 1] was raising her while running the Ice House restaurant, where Joey worked as a waitress. GQ described Joey as "kind of an uptight fussbudgetâ€”one who's always twisted up over doing the right thing and bungling-up ways to hook up with her crush and across the creek neighbor, Dawson."[6]


what is the meaning of a red sky in the morning

Red sky at morning The rhyme is a rule of thumb used for weather forecasting during the past two millennia. It is based on the reddish glow of the morning or evening sky, caused by haze or clouds related to storms in the region.[2][3][5] If the morning skies are red, it is because clear skies over the horizon to the east permit the sun to light the undersides of moisture-bearing clouds. The saying assumes that more such clouds are coming in from the west. Conversely, in order to see red clouds in the evening, sunlight must have a clear path from the west, so therefore the prevailing westerly wind must be bringing clear skies.


Tax protester statutory arguments A New York Times article on July 31, 2006, states that when filmmaker Aaron Russo asked an IRS spokesman for the law requiring payment of income taxes on wages and was provided a link to various documents including title 26 of the United States Code (the Internal Revenue Code), Russo denied that title 26 was the law, contending that it consisted only of IRS "regulations" and had not been enacted by Congress.


what type of glue is elmer's school glue

Elmer's Products Over the next few decades, Elmer's focused on expansion of adhesive products for school and home, in addition to developing a variety of hardware sealants, compounds, and caulks. In 1968, Elmer's introduced Elmer's School Glue, the first white glue that washed out of clothes.[5]


difference between common source common gate and common drain amplifier

Common source In electronics, a common-source amplifier is one of three basic single-stage field-effect transistor (FET) amplifier topologies, typically used as a voltage or transconductance amplifier. The easiest way to tell if a FET is common source, common drain, or common gate is to examine where the signal enters and leaves. The remaining terminal is what is known as "common". In this example, the signal enters the gate, and exits the drain. The only terminal remaining is the source. This is a common-source FET circuit. The analogous bipolar junction transistor circuit may be viewed as a transconductance amplifier or as a voltage amplifier. (See classification of amplifiers). As a transconductance amplifier, the input voltage is seen as modulating the current going to the load. As a voltage amplifier, input voltage modulates the amount of current flowing through the FET, changing the voltage across the output resistance according to Ohm's law. However, the FET device's output resistance typically is not high enough for a reasonable transconductance amplifier (ideally infinite), nor low enough for a decent voltage amplifier (ideally zero). Another major drawback is the amplifier's limited high-frequency response. Therefore, in practice the output often is routed through either a voltage follower (common-drain or CD stage), or a current follower (common-gate or CG stage), to obtain more favorable output and frequency characteristics. The CSâ€“CG combination is called a cascode amplifier.


Peyton Sawyer In season 3, Peyton learns that she was adopted, and that Ellie really is her biological mother. Lucas witnesses Ellie purchasing drugs, but he learns that she was buying them for medical reasons; she has breast cancer. Meanwhile, Peyton is angry with Haley because she left Tree Hill to go on tour, but soon they make amends, and Peyton reveals that her hostility toward Haley was because she was the only one that came back out of all the people who have left her. Peyton soon grows close to Ellie, and they collaborate on a CD called Friends with Benefit, which benefits breast cancer research; there will also be a concert for it at TRIC and Haley is one of the performers. Unfortunately, Ellie dies before she sees the CD or the concert, leaving Peyton devastated. A school shooting breaks out later in the season ("With Tired Eyes, Tired Minds, Tired Souls, We Slept"), where Peyton is left fighting for her life after being the one shot.Lucas and Nathan run inside the building to save Peyton and Haley; Lucas finds Peyton bleeding out of her leg inside the school's library. She cannot walk due to the injury, so escaping is out of the question. Lucas and Peyton stay in hiding, and Lucas wraps her leg, hoping to help the bleeding and pain subside. As Peyton is falling in and out of consciousness, he forces her to talk about a fun day she once had. Minutes later, after earning a promise from Lucas about everything being okay, Peyton loses hope of surviving, despite Lucas promising to get her out of there alive; she kisses him, wanting to let him know that she loves him before she dies. Lucas returns the kiss, and Peyton soon falls unconscious. Lucas, not wanting her to die, carries her out of the building, even at the risk of being killed by the shooter.


what is the meaning of the song angie by the rolling stones

Angie (song) There was speculation that the song was about David Bowie's first wife Angela,[4][5][6] Keith Richards' newborn daughter Dandelion Angela,[7][8] the actress Angie Dickinson,[7] and others. In 1993, in an interview for the liner notes to the Rolling Stones' compilation album Jump Back: The Best of The Rolling Stones, Richards said that the title was inspired by his baby daughter.[9] However, in his 2010 memoir Life, Richards said that he had chosen the name at random when writing the song — before he knew that his baby would be named Angela or even knew that his baby would be a girl — and that the song "was not about any particular person."[10] According to NME, Jagger's contributions to the lyrics referred to his breakup with Marianne Faithfull.[5]


who played the wizard in lord of the rings

Ian McKellen While filming the first X-Men film in 1999, McKellen was cast as the wizard Gandalf in Peter Jackson's three-film adaptation of The Lord of the Rings (consisting of The Fellowship of the Ring (2001), The Two Towers (2002), and The Return of the King (2003) ). He received honors from the Screen Actors Guild for Best Supporting Actor in a Motion Picture for his work in The Fellowship of the Ring, and was nominated for the Academy Award for Best Supporting Actor for the same role. He provided the voice of Gandalf for several video game adaptations of the Lord of the Rings films,[45] then reprised the role on screen in Jackson's film adaptation of The Hobbit, which was released in three parts from 2012 to 2014.[46]


mumford and sons i will wait video location

I Will Wait The music video was directed by Fred & Nick.[2] It was filmed at Red Rocks Amphitheatre in Morrison, Colorado.


when was the carbon tax repealed in australia

Carbon pricing in Australia A carbon pricing scheme in Australia, commonly dubbed by its critics as a "carbon tax", was introduced by the Gillard Labor Government in 2011 as the Clean Energy Act 2011 which came into effect on 1 July 2012. As a result of being in place for such a short time, and because the then Opposition leader Tony Abbott indicated he intended to repeal "the carbon tax", regulated organisations responded in a rather tepid and informal manner, with very few investments in emissions reductions being made.[2] The scheme was repealed on 17 July 2014, backdated to 1 July 2014. In its place the Abbott Government set up the Emission Reduction Fund in December 2014.


what is the prize for winning the national spelling bee

Scripps National Spelling Bee The winner of the Scripps National Spelling Bee receives a $40,000 cash prize and an engraved loving cup trophy from Scripps, a $2,500 savings bond, a reference library from Merriam-Webster, $2,600 in reference works and a lifetime membership to Britannica Online Premium from Encyclopædia Britannica, $5,000 cash prize from the Sigma Phi Epsilon Educational Foundation, and an online course and a Nook eReader from K12 Inc.


who is the character rocky balboa based on

Rocky Balboa Robert "Rocky" Balboa is the title character of the Rocky series. The character was created by Sylvester Stallone, who also portrayed him in all seven Rocky films. He is depicted as an everyman who started out by going the distance and overcoming obstacles that had occurred in his life and career as a professional boxer. While he is loosely based on Chuck Wepner, a one-time boxer who fought Muhammad Ali and lost on a TKO in the 15th round, the inspiration for the name, iconography and fighting style came from boxing legend Rocky Marciano.


what did the twelfth amendment to the constitution do

Twelfth Amendment to the United States Constitution The Twelfth Amendment (Amendment XII) to the United States Constitution provides the procedure for electing the President and Vice President. It replaced the procedure provided in Article II, Section 1, Clause 3, by which the Electoral College originally functioned. Problems with the original procedure arose in the elections of 1796 and 1800. The Twelfth Amendment refined the process whereby a President and a Vice President are elected by the Electoral College. The amendment was proposed by the Congress on December 9, 1803, and was ratified by the requisite three-fourths of state legislatures on June 15, 1804.


who has taken most wickets in one test match

List of Test cricket records The trend of countries to increase the number of Test matches they play means that the aggregate lists are dominated by modern players. Sri Lankan spinner Muttiah Muralitharan became the highest Test wicket-taker in December 2007, when he passed Shane Warne's total of 708 wickets.[19] Within a year, the equivalent batting record of highest run-scorer had also changed hands: Sachin Tendulkar surpassed the tally of 11,953 runs by Brian Lara.[20] The record for most dismissals by a wicket-keeper is held by Mark Boucher of South Africa[21] while the record for most catches by a fielder is held by Rahul Dravid.[22]


who invented the first television in the world

John Logie Baird John Logie Baird FRSE (/ˈloʊɡi bɛərd/;[1] 14 August 1888 – 14 June 1946) was a Scottish engineer, innovator, one of the inventors of the mechanical television, demonstrating the first working television system on 26 January 1926, and inventor of both the first publicly demonstrated colour television system, and the first purely electronic colour television picture tube.[2][3][4][5]


who played jerry lee lewis in great balls of fire

Great Balls of Fire! (film) Great Balls of Fire! is a 1989 American biographical film directed by Jim McBride and starring Dennis Quaid as rockabilly pioneer Jerry Lee Lewis. Based on a biography by Myra Lewis and Murray M. Silver Jr., the screenplay is written by McBride and Jack Baran. The film is produced by Adam Fields, with executive producers credited as Michael Grais, Mark Victor, and Art Levinson.[2]


who did the ottoman empire defeated in 1453

Fall of Constantinople The Fall of Constantinople (Greek: Ἅλωσις τῆς Κωνσταντινουπόλεως, Halōsis tēs Kōnstantinoupoleōs; Turkish: İstanbul'un Fethi Conquest of Istanbul) was the capture of the capital of the Byzantine Empire by an invading Ottoman army on 29 May 1453. The attackers were commanded by the then 21-year-old Sultan Mehmed II, who defeated an army commanded by Emperor Constantine XI Palaiologos and took control of the imperial capital, ending a 53-day siege that had begun on 6 April 1453. After conquering the city, Sultan Mehmed transferred the capital of his Empire from Edirne to Constantinople, and established his court there.


who is thought of as a pioneer of economic nationalism

Economic nationalism While the coining of the term "


when did the who play at the pontiac silverdome

Pontiac Silverdome The largest crowd to ever gather at the Silverdome was on September 18, 1987 for Mass with Pope John Paul II, with a reported attendance of 93,682 — just shading the record of 93,173 set at the Silverdome on March 29, 1987 for WrestleMania III. Another notable audience attendance record had earlier been broken on April 30, 1977, when the English rock band Led Zeppelin played in front of 76,229 fans at the Silverdome. This was, at the time, a new world record attendance for a solo indoor attraction, beating the 75,962 that The Who attracted there on December 6, 1975.[29] The Detroit Pistons also set numerous NBA attendance records during their time at the Silverdome; Regular Season, 61,983 vs. Boston, January 29, 1988; Playoffs, 41,732, vs. L.A. Lakers, June 16, 1988.[30]


what is the highest mountain peak in hawaii

Mauna Kea Mauna Kea (/ˌmɔːnə ˈkeɪ.ə/ or /ˌmaʊnə ˈkeɪ.ə/, Hawaiian: [ˈmɐwnə ˈkɛjə]), is a dormant volcano on the island of Hawaii. Standing 4,207 m (13,802 ft) above sea level, its peak is the highest point in the state of Hawaii. Much of the mountain is under water; when measured from its oceanic base, Mauna Kea is over 10,000 m (33,000 ft) tall and is the tallest mountain on Earth. Mauna Kea is about a million years old, and has thus passed the most active shield stage of life hundreds of thousands of years ago. In its current post-shield state, its lava is more viscous, resulting in a steeper profile. Late volcanism has also given it a much rougher appearance than its neighboring volcanoes; contributing factors include the construction of cinder cones, the decentralization of its rift zones, the glaciation on its peak, and the weathering effects of the prevailing trade winds. Mauna Kea last erupted 6,000 to 4,000 years ago and is now considered dormant.


who did jesse palmer end up with on the bachelor

Jesse Palmer In 2004, Palmer was the first professional athlete to appear on The Bachelor television program and the first non-American bachelor, in which he was given his choice of eligible single women. He eventually selected Jessica Bowlin, but their courtship lasted for only a few months after the end of the show.[19][20]


Fn key While it is most common for the Fn key processing to happen directly in the keyboard micro-controller, offering no knowledge to the main computer of whether the Fn key was pressed, some manufacturers, like Lenovo, perform this mapping in BIOS running on the main CPU, allowing remapping the Fn key by modifying the BIOS interrupt handler;[1] and Apple, in which the Fn key is mappable and serves other uses too, as triggering the Dictation function by pressing the Fn key twice.


who was the original owner of the new yorker hotel

Wyndham New Yorker Hotel The New Yorker Hotel was built by Garment Center developer Mack Kanner. When the project was announced in 1928, the Sugarman and Berger designed building was planned to be 38 stories, at an estimated cost of $8 million.[2][3] However, when it was completed in 1929, the building had grown to 43 stories, at a final cost of $22.5 million and contained 2,500 rooms, making it the city's largest for many years.[4][5] Hotel management pioneer Ralph Hitz was selected as its first manager, eventually becoming president of the National Hotel Management Company. An early ad for the building boasted that the hotel's "bell boys were 'as snappy-looking as West Pointers'" and "that it had a radio in every room with a choice of four stations".[6] It was a New Yorker bellboy, Johnny Roventini, who served as tobacco company Philip Morris' pitchman for twenty years, making famous their "Call for Philip Morris" advertising campaign.[7]


who has won the 2017 men's singles australian open tennis tournament

2017 Australian Open – Men's singles final The 2017 Australian Open Men's Singles final was the championship tennis match of the Men's Singles tournament at the 2017 Australian Open. It was contested between Roger Federer and Rafael Nadal, ranked 17th and 9th in the world respectively. It was their record ninth meeting in a Grand Slam final in their rivalry, and their 1st meeting in a Grand Slam final since the 2011 French Open. In a rematch of the 2009 Australian Open final, which Nadal won in 5 sets, Roger Federer won the duel in 5 sets, beating Nadal for the first time in a Grand Slam since the 2007 Wimbledon final. He also trailed Nadal 3–1 in the final set but won 5 games in a row to win the title. This ended a 6-match losing streak against Nadal in Grand Slam events. Having lost all of their previous three encounters, this was the first time Federer defeated Nadal at the Australian Open and also marked Federer's first Grand Slam victory over Nadal outside the grass courts of Wimbledon. Federer extended his record of Grand Slam men's singles titles to 18, marking the third time he broke his own all-time record, after breaking the previous record of 14, held by Pete Sampras.


who died on the plane crash in grey's anatomy

Flight (Grey's Anatomy) "Flight" is the twenty-fourth and final episode of the eighth season of the American television medical drama Grey's Anatomy, and the show's 172nd episode overall. It was written by series creator Shonda Rhimes, and directed by Rob Corn. The episode was originally broadcast on the American Broadcasting Company (ABC) in the United States on May 17, 2012. In the episode, six doctors from Seattle Grace Mercy West Hospital who are victims of an aviation accident fight to stay alive, but Dr. Lexie Grey (Chyler Leigh) ultimately dies. Other storylines occur in Seattle where Dr. Richard Webber (James Pickens, Jr.) plans his annual dinner for the departing residents, Dr. Owen Hunt (Kevin McKidd) fires Dr. Teddy Altman (Kim Raver), and Dr. Miranda Bailey (Chandra Wilson) gets engaged.


bank of america branches in the united states

Bank of America Both Bank of America Merrill Lynch and Merrill Lynch Wealth Management retain large market shares in their respective offerings. The investment bank is considered within the "Bulge Bracket" as the third largest investment bank in the world, as of 2018.[4] Its wealth management side manages US$1.081 trillion in assets under management (AUM) as the second largest wealth manager in the world, after UBS.[5] In commercial banking, Bank of America operates—but does not necessarily maintain retail branches–in all 50 states of the United States, the District of Columbia and more than 40 other countries.[6] Its commercial banking footprint encapsulates 46 million consumer and small business relationships at 4,600 banking centers and 15,900 automated teller machines (ATMs).


Lady and the Tramp Lady and the Tramp is a 1955 American animated musical romance film produced by Walt Disney and released to theaters on June 22, 1955 by Buena Vista Distribution. The 15th Disney animated feature film, it was the first animated feature filmed in the CinemaScope widescreen film process.[3] Based on Happy Dan, The Cynical Dog by Ward Greene, Lady and the Tramp tells the story of a female American Cocker Spaniel named Lady who lives with a refined, upper-middle-class family, and a male stray mongrel called the Tramp. When the two dogs meet, they embark on many romantic adventures and fall in love. A direct-to-video sequel, Lady and the Tramp II: Scamp's Adventure, was released in 2001.


2018 FIFA World Cup The 2018 FIFA World Cup was the 21st FIFA World Cup, an international football tournament contested by the men's national teams of the member associations of FIFA once every four years. It took place in Russia from 14 June to 15 July 2018.[2] It was the first World Cup to be held in Eastern Europe,[3] and the 11th time that it had been held in Europe. At an estimated cost of over $14.2Â billion, it was the most expensive World Cup.[4] It was also the first World Cup to use the video assistant referee (VAR) system.[5][6]


who is the girl from we don't talk anymore

We Don't Talk Anymore (Charlie Puth song) "We Don't Talk Anymore" is a song produced and performed by American singer Charlie Puth from his debut studio album Nine Track Mind (2016). It contains guest vocals from Selena Gomez. Jacob Kasher co-wrote the track with the artists. The song was released on May 24, 2016,[1] as the third and final single from the album. Musically, it is a pop song with tropical-inspired production.


where do noncompetitive inhibitors bind on an enzyme

Non-competitive inhibition The most common mechanism of non-competitive inhibition involves reversible binding of the inhibitor to an allosteric site, but it is possible for the inhibitor to operate via other means including direct binding to the active site. It differs from competitive inhibition in that the binding of the inhibitor does not prevent binding of substrate, and vice versa, it simply prevents product formation for a limited time.


when did the new horizons mission reach pluto

New Horizons On July 14, 2015, at 11:49 UTC, it flew 12,500 km (7,800 mi) above the surface of Pluto,[11][12] making it the first spacecraft to explore the dwarf planet.[7][13] On October 25, 2016, at 21:48 UTC, the last of the recorded data from the Pluto flyby was received from New Horizons.[14] Having completed its flyby of Pluto,[15] New Horizons has maneuvered for a flyby of Kuiper belt object (486958) 2014 MU69,[16][17][18] expected to take place on January 1, 2019, when it will be 43.4 AU from the Sun.[16][17]


where was the new dukes of hazzard filmed

The Dukes of Hazzard (film) The majority of the film was shot in and around Clinton, Louisiana.