DDInter1079 DDInter832
Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and [captopril] are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. Lisinopril was granted FDA approval on 29 December 1987.
A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Lisinopril {u} (Compound) resembles {v} (Compound) Enalapril
Lisinopril {u} (Compound) resembles {v} (Compound) Trandolapril
Lisinopril {u} (Compound) treats {v} (Disease) hypertension
Lisinopril {u} (Compound) binds {v} (Gene) ABCB1
Lisinopril {u} (Compound) downregulates {v} (Gene) ALAS1
Lisinopril {u} (Compound) causes {v} (Side Effect) Inappropriate antidiuretic hormone secretion
Lisinopril {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium oxide
Lisinopril {u} may cause a minor interaction that can limit clinical effects when taken with {v} Erythropoietin
Lisinopril {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Idelalisib
Lisinopril {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Urokinase
Lisinopril (Compound) resembles Enalapril (Compound)
Lisinopril (Compound) resembles Trandolapril (Compound)
Lisinopril (Compound) treats hypertension (Disease)
Lisinopril (Compound) binds ABCB1 (Gene)
Lisinopril (Compound) downregulates ALAS1 (Gene)
Lisinopril (Compound) causes Inappropriate antidiuretic hormone secretion (Side Effect)
Lisinopril may cause a minor interaction that can limit clinical effects when taken with Magnesium oxide
Lisinopril may cause a minor interaction that can limit clinical effects when taken with Erythropoietin
Lisinopril may cause a moderate interaction that could exacerbate diseases when taken with Idelalisib
Lisinopril may cause a moderate interaction that could exacerbate diseases when taken with Urokinase