DDInter689 DDInter1938
Ethambutol is a bacteriostatic agent indicated alongside medications such as [isoniazid], [rifampin], and [pyrazinamide] in the treatment of pulmonary tuberculosis. Ethambutol was first described in the literature in 1961. It was developed out of a need for therapies active against isoniazid resistant strains of _Mycobacterium tuberculosis_. Ethambutol was granted FDA approval on 6 November 1967.
Vincristine is a vinca alkaloid with formula C46H56N4O10 found in the Madagascar periwinkle, Catharanthus roseus. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer. It has a role as a tubulin modulator, a microtubule-destabilising agent, a plant metabolite, an antineoplastic agent and a drug. It is a methyl ester, an acetate ester, a tertiary alcohol, a member of formamides, an organic heteropentacyclic compound, an organic heterotetracyclic compound, a tertiary amino compound and a vinca alkaloid. It is a conjugate base of a vincristine(2+). It derives from a hydride of a vincaleukoblastine.
Ethambutol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Vinorelbine
Vinorelbine {u} (Compound) resembles {v} (Compound) Vincristine
Ethambutol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Vinblastine
Vinblastine {u} (Compound) resembles {v} (Compound) Vincristine
Ethambutol {u} (Compound) upregulates {v} (Gene) KLHL21
KLHL21 {u} (Gene) is upregulated by {v} (Compound) Vincristine
Ethambutol {u} (Compound) causes {v} (Side Effect) Neutropenia
Neutropenia {u} (Side Effect) is caused by {v} (Compound) Vincristine
Ethambutol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Vinorelbine
Vinorelbine {u} (Compound) resembles {v} (Compound) Voacamine
Voacamine {u} (Compound) resembles {v} (Compound) Vincristine
Ethambutol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Vinblastine
Vinblastine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Vinorelbine
Vinorelbine {u} (Compound) resembles {v} (Compound) Vincristine
Ethambutol {u} (Compound) upregulates {v} (Gene) KLHL21
KLHL21 {u} (Gene) is upregulated by {v} (Compound) Vinorelbine
Vinorelbine {u} (Compound) resembles {v} (Compound) Vincristine
Ethambutol {u} (Compound) causes {v} (Side Effect) Neutropenia
Neutropenia {u} (Side Effect) is caused by {v} (Compound) Vinorelbine
Vinorelbine {u} (Compound) resembles {v} (Compound) Vincristine
Ethambutol {u} (Compound) causes {v} (Side Effect) Neuritis
Neuritis {u} (Side Effect) is caused by {v} (Compound) Vinblastine
Vinblastine {u} (Compound) resembles {v} (Compound) Vincristine
Ethambutol {u} (Compound) downregulates {v} (Gene) TARBP1
TARBP1 {u} (Gene) is regulated by {v} (Gene) CCDC85B
CCDC85B {u} (Gene) is downregulated by {v} (Compound) Vincristine
Ethambutol may cause a moderate interaction that could exacerbate diseases when taken with Vinorelbine and Vinorelbine (Compound) resembles Vincristine (Compound)
Ethambutol may cause a moderate interaction that could exacerbate diseases when taken with Vinblastine and Vinblastine (Compound) resembles Vincristine (Compound)
Ethambutol (Compound) upregulates KLHL21 (Gene) and KLHL21 (Gene) is upregulated by Vincristine (Compound)
Ethambutol (Compound) causes Neutropenia (Side Effect) and Neutropenia (Side Effect) is caused by Vincristine (Compound)
Ethambutol may cause a moderate interaction that could exacerbate diseases when taken with Vinorelbine and Vinorelbine (Compound) resembles Voacamine (Compound) and Voacamine (Compound) resembles Vincristine (Compound)
Ethambutol may cause a moderate interaction that could exacerbate diseases when taken with Vinblastine and Vinblastine may cause a moderate interaction that could exacerbate diseases when taken with Vinorelbine and Vinorelbine (Compound) resembles Vincristine (Compound)
Ethambutol (Compound) upregulates KLHL21 (Gene) and KLHL21 (Gene) is upregulated by Vinorelbine (Compound) and Vinorelbine (Compound) resembles Vincristine (Compound)
Ethambutol (Compound) causes Neutropenia (Side Effect) and Neutropenia (Side Effect) is caused by Vinorelbine (Compound) and Vinorelbine (Compound) resembles Vincristine (Compound)
Ethambutol (Compound) causes Neuritis (Side Effect) and Neuritis (Side Effect) is caused by Vinblastine (Compound) and Vinblastine (Compound) resembles Vincristine (Compound)
Ethambutol (Compound) downregulates TARBP1 (Gene) and TARBP1 (Gene) is regulated by CCDC85B (Gene) and CCDC85B (Gene) is downregulated by Vincristine (Compound)