DDInter655 DDInter1956
An anthracycline which is the 4&#39;-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the elongation of DNA chains, thus resulting in the termination of viral DNA growth. The compound is a potent inhibitor of HIV replication at low concentrations, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Its principal toxic side effect is axonal degeneration resulting in peripheral neuropathy.
Epirubicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Emtricitabine
Emtricitabine {u} (Compound) resembles {v} (Compound) Zalcitabine
Epirubicin {u} (Compound) downregulates {v} (Gene) DCK
DCK {u} (Gene) is bound by {v} (Compound) Zalcitabine
Epirubicin {u} (Compound) upregulates {v} (Gene) TRAPPC6A
TRAPPC6A {u} (Gene) is upregulated by {v} (Compound) Zalcitabine
Epirubicin {u} (Compound) downregulates {v} (Gene) NUP85
NUP85 {u} (Gene) is downregulated by {v} (Compound) Zalcitabine
Epirubicin {u} (Compound) causes {v} (Side Effect) Pollakiuria
Pollakiuria {u} (Side Effect) is caused by {v} (Compound) Zalcitabine
Epirubicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Emtricitabine
Emtricitabine {u} (Compound) resembles {v} (Compound) Lamivudine
Lamivudine {u} (Compound) resembles {v} (Compound) Zalcitabine
Epirubicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Didanosine
Didanosine {u} (Compound) binds {v} (Gene) SLC22A6
SLC22A6 {u} (Gene) is bound by {v} (Compound) Zalcitabine
Epirubicin {u} (Compound) downregulates {v} (Gene) DCK
DCK {u} (Gene) is bound by {v} (Compound) Emtricitabine
Emtricitabine {u} (Compound) resembles {v} (Compound) Zalcitabine
Epirubicin {u} (Compound) upregulates {v} (Gene) TRAPPC6A
TRAPPC6A {u} (Gene) regulates {v} (Gene) NUP85
NUP85 {u} (Gene) is downregulated by {v} (Compound) Zalcitabine
Epirubicin {u} (Compound) upregulates {v} (Gene) GPC1
GPC1 {u} (Gene) is upregulated by {v} (Compound) Gemcitabine
Gemcitabine {u} (Compound) resembles {v} (Compound) Zalcitabine
Epirubicin may cause a moderate interaction that could exacerbate diseases when taken with Emtricitabine and Emtricitabine (Compound) resembles Zalcitabine (Compound)
Epirubicin (Compound) downregulates DCK (Gene) and DCK (Gene) is bound by Zalcitabine (Compound)
Epirubicin (Compound) upregulates TRAPPC6A (Gene) and TRAPPC6A (Gene) is upregulated by Zalcitabine (Compound)
Epirubicin (Compound) downregulates NUP85 (Gene) and NUP85 (Gene) is downregulated by Zalcitabine (Compound)
Epirubicin (Compound) causes Pollakiuria (Side Effect) and Pollakiuria (Side Effect) is caused by Zalcitabine (Compound)
Epirubicin may cause a moderate interaction that could exacerbate diseases when taken with Emtricitabine and Emtricitabine (Compound) resembles Lamivudine (Compound) and Lamivudine (Compound) resembles Zalcitabine (Compound)
Epirubicin may cause a moderate interaction that could exacerbate diseases when taken with Didanosine and Didanosine (Compound) binds SLC22A6 (Gene) and SLC22A6 (Gene) is bound by Zalcitabine (Compound)
Epirubicin (Compound) downregulates DCK (Gene) and DCK (Gene) is bound by Emtricitabine (Compound) and Emtricitabine (Compound) resembles Zalcitabine (Compound)
Epirubicin (Compound) upregulates TRAPPC6A (Gene) and TRAPPC6A (Gene) regulates NUP85 (Gene) and NUP85 (Gene) is downregulated by Zalcitabine (Compound)
Epirubicin (Compound) upregulates GPC1 (Gene) and GPC1 (Gene) is upregulated by Gemcitabine (Compound) and Gemcitabine (Compound) resembles Zalcitabine (Compound)