DDInter1887 DDInter1826
Trovafloxacin is a broad spectrum antibiotic that has been commonly marketed under the brand name Trovan by Pfizer. It exerts its antibacterial activity by inhibiting the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV. It was shown to be more effective against Gram-positive bacteria than Gram-negative bacteria when compared to previous fluoroquinolones. Due to its hepatotoxic potential, trovafloxacin was withdrawn from the market.
A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Trovafloxacin {u} may lead to a major life threatening interaction when taken with {v} Tolbutamide
Tolbutamide {u} (Compound) resembles {v} (Compound) Tolazamide
Trovafloxacin {u} (Compound) causes {v} (Side Effect) Headache
Headache {u} (Side Effect) is caused by {v} (Compound) Tolazamide
Trovafloxacin {u} may lead to a major life threatening interaction when taken with {v} Tolbutamide
Tolbutamide {u} (Compound) resembles {v} (Compound) Sulfacetamide
Sulfacetamide {u} (Compound) resembles {v} (Compound) Tolazamide
Trovafloxacin {u} may lead to a major life threatening interaction when taken with {v} Glipizide
Glipizide {u} (Compound) resembles {v} (Compound) Tolbutamide
Tolbutamide {u} (Compound) resembles {v} (Compound) Tolazamide
Trovafloxacin {u} (Compound) causes {v} (Side Effect) Headache
Headache {u} (Side Effect) is caused by {v} (Compound) Tolbutamide
Tolbutamide {u} (Compound) resembles {v} (Compound) Tolazamide
Trovafloxacin {u} may lead to a major life threatening interaction when taken with {v} Glimepiride
Glimepiride {u} (Compound) resembles {v} (Compound) Tolbutamide
Tolbutamide {u} (Compound) resembles {v} (Compound) Tolazamide
Trovafloxacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sodium citrate
Sodium citrate {u} may cause a minor interaction that can limit clinical effects when taken with {v} Tolbutamide
Tolbutamide {u} (Compound) resembles {v} (Compound) Tolazamide
Trovafloxacin {u} may lead to a major life threatening interaction when taken with {v} Glimepiride
Glimepiride {u} (Compound) resembles {v} (Compound) Glisoxepide
Glisoxepide {u} (Compound) resembles {v} (Compound) Tolazamide
Trovafloxacin {u} may lead to a major life threatening interaction when taken with {v} Insulin degludec
Insulin degludec {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tolbutamide
Tolbutamide {u} (Compound) resembles {v} (Compound) Tolazamide
Trovafloxacin {u} may lead to a major life threatening interaction when taken with {v} Warfarin
Warfarin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tolbutamide
Tolbutamide {u} (Compound) resembles {v} (Compound) Tolazamide
Trovafloxacin may lead to a major life threatening interaction when taken with Tolbutamide and Tolbutamide (Compound) resembles Tolazamide (Compound)
Trovafloxacin (Compound) causes Headache (Side Effect) and Headache (Side Effect) is caused by Tolazamide (Compound)
Trovafloxacin may lead to a major life threatening interaction when taken with Tolbutamide and Tolbutamide (Compound) resembles Sulfacetamide (Compound) and Sulfacetamide (Compound) resembles Tolazamide (Compound)
Trovafloxacin may lead to a major life threatening interaction when taken with Glipizide and Glipizide (Compound) resembles Tolbutamide (Compound) and Tolbutamide (Compound) resembles Tolazamide (Compound)
Trovafloxacin (Compound) causes Headache (Side Effect) and Headache (Side Effect) is caused by Tolbutamide (Compound) and Tolbutamide (Compound) resembles Tolazamide (Compound)
Trovafloxacin may lead to a major life threatening interaction when taken with Glimepiride and Glimepiride (Compound) resembles Tolbutamide (Compound) and Tolbutamide (Compound) resembles Tolazamide (Compound)
Trovafloxacin may cause a moderate interaction that could exacerbate diseases when taken with Sodium citrate and Sodium citrate may cause a minor interaction that can limit clinical effects when taken with Tolbutamide and Tolbutamide (Compound) resembles Tolazamide (Compound)
Trovafloxacin may lead to a major life threatening interaction when taken with Glimepiride and Glimepiride (Compound) resembles Glisoxepide (Compound) and Glisoxepide (Compound) resembles Tolazamide (Compound)
Trovafloxacin may lead to a major life threatening interaction when taken with Insulin degludec and Insulin degludec may cause a moderate interaction that could exacerbate diseases when taken with Tolbutamide and Tolbutamide (Compound) resembles Tolazamide (Compound)
Trovafloxacin may lead to a major life threatening interaction when taken with Warfarin and Warfarin may cause a moderate interaction that could exacerbate diseases when taken with Tolbutamide and Tolbutamide (Compound) resembles Tolazamide (Compound)