DDInter380 DDInter1860
A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Withdrawn in the United Kingdom due to risk of psychiatric adverse drug reactions. This drug continues to be available in the U.S. Internationally, triazolam is a Schedule IV drug under the Convention on Psychotropic Substances.
Cimetidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Halazepam
Halazepam {u} (Compound) resembles {v} (Compound) Triazolam
Cimetidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Chlordiazepoxide
Chlordiazepoxide {u} (Compound) resembles {v} (Compound) Triazolam
Cimetidine {u} (Compound) binds {v} (Gene) CYP3A5
CYP3A5 {u} (Gene) is bound by {v} (Compound) Triazolam
Cimetidine {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Triazolam
Cimetidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Halazepam
Halazepam {u} (Compound) resembles {v} (Compound) Camazepam
Camazepam {u} (Compound) resembles {v} (Compound) Triazolam
Cimetidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Quazepam
Quazepam {u} (Compound) resembles {v} (Compound) Flunitrazepam
Flunitrazepam {u} (Compound) resembles {v} (Compound) Triazolam
Cimetidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Chlordiazepoxide
Chlordiazepoxide {u} (Compound) resembles {v} (Compound) Camazepam
Camazepam {u} (Compound) resembles {v} (Compound) Triazolam
Cimetidine {u} (Compound) binds {v} (Gene) CYP3A5
CYP3A5 {u} (Gene) is bound by {v} (Compound) Midazolam
Midazolam {u} (Compound) resembles {v} (Compound) Triazolam
Cimetidine {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Flunitrazepam
Flunitrazepam {u} (Compound) resembles {v} (Compound) Triazolam
Cimetidine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Chlorpromazine
Chlorpromazine {u} (Compound) resembles {v} (Compound) Camazepam
Camazepam {u} (Compound) resembles {v} (Compound) Triazolam
Cimetidine may cause a moderate interaction that could exacerbate diseases when taken with Halazepam and Halazepam (Compound) resembles Triazolam (Compound)
Cimetidine may cause a moderate interaction that could exacerbate diseases when taken with Chlordiazepoxide and Chlordiazepoxide (Compound) resembles Triazolam (Compound)
Cimetidine (Compound) binds CYP3A5 (Gene) and CYP3A5 (Gene) is bound by Triazolam (Compound)
Cimetidine (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Triazolam (Compound)
Cimetidine may cause a moderate interaction that could exacerbate diseases when taken with Halazepam and Halazepam (Compound) resembles Camazepam (Compound) and Camazepam (Compound) resembles Triazolam (Compound)
Cimetidine may cause a moderate interaction that could exacerbate diseases when taken with Quazepam and Quazepam (Compound) resembles Flunitrazepam (Compound) and Flunitrazepam (Compound) resembles Triazolam (Compound)
Cimetidine may cause a moderate interaction that could exacerbate diseases when taken with Chlordiazepoxide and Chlordiazepoxide (Compound) resembles Camazepam (Compound) and Camazepam (Compound) resembles Triazolam (Compound)
Cimetidine (Compound) binds CYP3A5 (Gene) and CYP3A5 (Gene) is bound by Midazolam (Compound) and Midazolam (Compound) resembles Triazolam (Compound)
Cimetidine (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Flunitrazepam (Compound) and Flunitrazepam (Compound) resembles Triazolam (Compound)
Cimetidine may cause a minor interaction that can limit clinical effects when taken with Chlorpromazine and Chlorpromazine (Compound) resembles Camazepam (Compound) and Camazepam (Compound) resembles Triazolam (Compound)