DDInter1607 DDInter1513
Ritonavir is an HIV protease inhibitor that interferes with the reproductive cycle of HIV. Although it was initially developed as an independent antiviral agent, it has been shown to possess advantageous properties in combination regimens with low-dose ritonavir and other protease inhibitors. It is now more commonly used as a booster of other protease inhibitors and is available in both liquid formulations and as capsules. While ritonavir is not an active antiviral agent against hepatitis C virus (HCV) infection, it is added in combination therapies indicated for the treatment of HCV infections as a booster. Ritonavir is a potent CYP3A inhibitor that increases peak and trough plasma drug concentrations of other protease inhibitors such as and overall drug exposure. American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) guidelines recommend ritonavir-boosted combination therapies as first-line therapy for HCV Genotype 1a/b and
Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Ritonavir {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Prednisolone
Ritonavir {u} (Compound) causes {v} (Side Effect) Hiccups
Hiccups {u} (Side Effect) is caused by {v} (Compound) Prednisolone
Ritonavir {u} (Compound) resembles {v} (Compound) Atazanavir
Atazanavir {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Prednisolone
Ritonavir {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Hydrocortamate
Hydrocortamate {u} (Compound) resembles {v} (Compound) Prednisolone
Ritonavir {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Progesterone
Progesterone {u} (Compound) resembles {v} (Compound) Prednisolone
Ritonavir {u} (Compound) binds {v} (Gene) SLCO1A2
SLCO1A2 {u} (Gene) is bound by {v} (Compound) Testosterone
Testosterone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Prednisolone
Ritonavir {u} (Compound) causes {v} (Side Effect) Hiccups
Hiccups {u} (Side Effect) is caused by {v} (Compound) Triamcinolone
Triamcinolone {u} (Compound) resembles {v} (Compound) Prednisolone
Ritonavir {u} (Compound) causes {v} (Side Effect) Urticaria
Urticaria {u} (Side Effect) is caused by {v} (Compound) Progesterone
Progesterone {u} (Compound) resembles {v} (Compound) Prednisolone
Ritonavir {u} (Compound) resembles {v} (Compound) Carfilzomib
Carfilzomib {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Prednisolone
Ritonavir {u} (Compound) resembles {v} (Compound) Atazanavir
Atazanavir {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Flunisolide
Flunisolide {u} (Compound) resembles {v} (Compound) Prednisolone
Ritonavir (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Prednisolone (Compound)
Ritonavir (Compound) causes Hiccups (Side Effect) and Hiccups (Side Effect) is caused by Prednisolone (Compound)
Ritonavir (Compound) resembles Atazanavir (Compound) and Atazanavir may cause a moderate interaction that could exacerbate diseases when taken with Prednisolone
Ritonavir (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Hydrocortamate (Compound) and Hydrocortamate (Compound) resembles Prednisolone (Compound)
Ritonavir (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Progesterone (Compound) and Progesterone (Compound) resembles Prednisolone (Compound)
Ritonavir (Compound) binds SLCO1A2 (Gene) and SLCO1A2 (Gene) is bound by Testosterone (Compound) and Testosterone may cause a moderate interaction that could exacerbate diseases when taken with Prednisolone
Ritonavir (Compound) causes Hiccups (Side Effect) and Hiccups (Side Effect) is caused by Triamcinolone (Compound) and Triamcinolone (Compound) resembles Prednisolone (Compound)
Ritonavir (Compound) causes Urticaria (Side Effect) and Urticaria (Side Effect) is caused by Progesterone (Compound) and Progesterone (Compound) resembles Prednisolone (Compound)
Ritonavir (Compound) resembles Carfilzomib (Compound) and Carfilzomib (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Prednisolone (Compound)
Ritonavir (Compound) resembles Atazanavir (Compound) and Atazanavir may cause a moderate interaction that could exacerbate diseases when taken with Flunisolide and Flunisolide (Compound) resembles Prednisolone (Compound)