DDInter1759 DDInter65
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arterial blood pressure.[A1489,A1490] Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects.
A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Telmisartan {u} (Compound) causes {v} (Side Effect) Shock
Shock {u} (Side Effect) is caused by {v} (Compound) Amifostine
Telmisartan {u} (Compound) resembles {v} (Compound) Azilsartan medoxomil
Azilsartan medoxomil {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amifostine
Telmisartan {u} (Compound) resembles {v} (Compound) Olmesartan
Olmesartan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amifostine
Telmisartan {u} (Compound) causes {v} (Side Effect) Shock
Shock {u} (Side Effect) is caused by {v} (Compound) Nifedipine
Nifedipine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amifostine
Telmisartan {u} (Compound) causes {v} (Side Effect) Toxic skin eruption
Toxic skin eruption {u} (Side Effect) is caused by {v} (Compound) Silodosin
Silodosin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amifostine
Telmisartan {u} (Compound) resembles {v} (Compound) Azilsartan medoxomil
Azilsartan medoxomil {u} (Compound) causes {v} (Side Effect) Rash
Rash {u} (Side Effect) is caused by {v} (Compound) Amifostine
Telmisartan {u} (Compound) binds {v} (Gene) PPARG
PPARG {u} (Gene) regulates {v} (Gene) ERAP2
ERAP2 {u} (Gene) is upregulated by {v} (Compound) Amifostine
Telmisartan {u} (Compound) binds {v} (Gene) PPARG
PPARG {u} (Gene) is regulated by {v} (Gene) PUF60
PUF60 {u} (Gene) is downregulated by {v} (Compound) Amifostine
Telmisartan {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) regulates {v} (Gene) PUF60
PUF60 {u} (Gene) is downregulated by {v} (Compound) Amifostine
Telmisartan {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Nifedipine
Nifedipine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amifostine
Telmisartan (Compound) causes Shock (Side Effect) and Shock (Side Effect) is caused by Amifostine (Compound)
Telmisartan (Compound) resembles Azilsartan medoxomil (Compound) and Azilsartan medoxomil may cause a moderate interaction that could exacerbate diseases when taken with Amifostine
Telmisartan (Compound) resembles Olmesartan (Compound) and Olmesartan may cause a moderate interaction that could exacerbate diseases when taken with Amifostine
Telmisartan (Compound) causes Shock (Side Effect) and Shock (Side Effect) is caused by Nifedipine (Compound) and Nifedipine may cause a moderate interaction that could exacerbate diseases when taken with Amifostine
Telmisartan (Compound) causes Toxic skin eruption (Side Effect) and Toxic skin eruption (Side Effect) is caused by Silodosin (Compound) and Silodosin may cause a moderate interaction that could exacerbate diseases when taken with Amifostine
Telmisartan (Compound) resembles Azilsartan medoxomil (Compound) and Azilsartan medoxomil (Compound) causes Rash (Side Effect) and Rash (Side Effect) is caused by Amifostine (Compound)
Telmisartan (Compound) binds PPARG (Gene) and PPARG (Gene) regulates ERAP2 (Gene) and ERAP2 (Gene) is upregulated by Amifostine (Compound)
Telmisartan (Compound) binds PPARG (Gene) and PPARG (Gene) is regulated by PUF60 (Gene) and PUF60 (Gene) is downregulated by Amifostine (Compound)
Telmisartan (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) regulates PUF60 (Gene) and PUF60 (Gene) is downregulated by Amifostine (Compound)
Telmisartan (Compound) treats hypertension (Disease) and hypertension (Disease) is treated by Nifedipine (Compound) and Nifedipine may cause a moderate interaction that could exacerbate diseases when taken with Amifostine