DDInter1164 DDInter1141
Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173] Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels. Another well-known benefit of this drug is modest weight loss, making it an effective choice for obese patients type II diabetes. Metformin was first approved in Canada in 1972, and received subsequent FDA approval in the US in 1995.
17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fludrocortisone
Fludrocortisone {u} (Compound) resembles {v} (Compound) Megestrol acetate
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Medroxyprogesterone acetate
Medroxyprogesterone acetate {u} (Compound) resembles {v} (Compound) Megestrol acetate
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fludrocortisone
Fludrocortisone {u} (Compound) resembles {v} (Compound) Dydrogesterone
Dydrogesterone {u} (Compound) resembles {v} (Compound) Megestrol acetate
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Spironolactone
Spironolactone {u} (Compound) resembles {v} (Compound) Dydrogesterone
Dydrogesterone {u} (Compound) resembles {v} (Compound) Megestrol acetate
Metformin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Amcinonide
Amcinonide {u} (Compound) resembles {v} (Compound) Difluprednate
Difluprednate {u} (Compound) resembles {v} (Compound) Megestrol acetate
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fludrocortisone
Fludrocortisone {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fluoxymesterone
Fluoxymesterone {u} (Compound) resembles {v} (Compound) Megestrol acetate
Metformin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Amcinonide
Amcinonide {u} (Compound) resembles {v} (Compound) Fluoxymesterone
Fluoxymesterone {u} (Compound) resembles {v} (Compound) Megestrol acetate
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fludrocortisone
Fludrocortisone {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methyltestosterone
Methyltestosterone {u} (Compound) resembles {v} (Compound) Megestrol acetate
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Spironolactone
Spironolactone {u} (Compound) resembles {v} (Compound) Methyltestosterone
Methyltestosterone {u} (Compound) resembles {v} (Compound) Megestrol acetate
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Spironolactone
Spironolactone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fludrocortisone
Fludrocortisone {u} (Compound) resembles {v} (Compound) Megestrol acetate
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Fludrocortisone and Fludrocortisone (Compound) resembles Megestrol acetate (Compound)
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Medroxyprogesterone acetate and Medroxyprogesterone acetate (Compound) resembles Megestrol acetate (Compound)
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Fludrocortisone and Fludrocortisone (Compound) resembles Dydrogesterone (Compound) and Dydrogesterone (Compound) resembles Megestrol acetate (Compound)
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Spironolactone and Spironolactone (Compound) resembles Dydrogesterone (Compound) and Dydrogesterone (Compound) resembles Megestrol acetate (Compound)
Metformin may cause a minor interaction that can limit clinical effects when taken with Amcinonide and Amcinonide (Compound) resembles Difluprednate (Compound) and Difluprednate (Compound) resembles Megestrol acetate (Compound)
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Fludrocortisone and Fludrocortisone (Compound) resembles Fluoxymesterone (Compound) and Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Fluoxymesterone and Fluoxymesterone (Compound) resembles Megestrol acetate (Compound)
Metformin may cause a minor interaction that can limit clinical effects when taken with Amcinonide and Amcinonide (Compound) resembles Fluoxymesterone (Compound) and Fluoxymesterone (Compound) resembles Megestrol acetate (Compound)
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Fludrocortisone and Fludrocortisone (Compound) resembles Methyltestosterone (Compound) and Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Methyltestosterone and Methyltestosterone (Compound) resembles Megestrol acetate (Compound)
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Spironolactone and Spironolactone (Compound) resembles Methyltestosterone (Compound) and Methyltestosterone (Compound) resembles Megestrol acetate (Compound)
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Spironolactone and Spironolactone may cause a moderate interaction that could exacerbate diseases when taken with Fludrocortisone and Fludrocortisone (Compound) resembles Megestrol acetate (Compound)