DDInter698 DDInter964
Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid]. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and [risedronic acid]. Etidronic acid was granted FDA approval on 1 September 1977.
Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. It functions as a contrast agent by opacifying blood vessels in the flow path of the contrast agent, permitting radiographic visualization of the internal structures until significant hemodilution occurs. Although iopromide can cause several serious adverse effects, including cardiac events, thromboembolism, hypersensitivity reaction, and even death if administered intrathecally inadvertently, it is still deemed to have a favorable safety profile, with only 0.7% of patients in a 2 years study experiencing adverse events. Although the mechanism is unclear, women and outpatients tend to have a higher incidence of adverse events compared to other population groups. Approved by the FDA in 1995 and Health Canada in 1994 under the brand name ULTRAVIST, iopromide is used in radiological diagnosis, including, but not limited to, intra-arterial digital subtraction angiography (IA-DSA), cerebral and peripheral arteriography, peripheral venography, excretory urography, brain computer tomography (CT), coronary arteriography, left ventriculography, visceral angiography, and orthography.[L46906,L46911]
Etidronic acid {u} (Compound) resembles {v} (Compound) Zoledronic acid
Zoledronic acid {u} may lead to a major life threatening interaction when taken with {v} Iopromide
Etidronic acid {u} (Compound) resembles {v} (Compound) Zoledronic acid
Zoledronic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clofarabine
Clofarabine {u} may lead to a major life threatening interaction when taken with {v} Iopromide
Etidronic acid {u} (Compound) resembles {v} (Compound) Ibandronate
Ibandronate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clofarabine
Clofarabine {u} may lead to a major life threatening interaction when taken with {v} Iopromide
Etidronic acid {u} (Compound) resembles {v} (Compound) Risedronic acid
Risedronic acid {u} (Compound) resembles {v} (Compound) Pamidronic acid
Pamidronic acid {u} may lead to a major life threatening interaction when taken with {v} Iopromide
Etidronic acid {u} (Compound) resembles {v} (Compound) Zoledronic acid
Zoledronic acid {u} (Compound) resembles {v} (Compound) Ibandronate
Ibandronate {u} may lead to a major life threatening interaction when taken with {v} Iopromide
Etidronic acid {u} (Compound) resembles {v} (Compound) Clodronate
Clodronate {u} (Compound) resembles {v} (Compound) Zoledronic acid
Zoledronic acid {u} may lead to a major life threatening interaction when taken with {v} Iopromide
Etidronic acid {u} (Compound) treats {v} (Disease) Paget's disease of bone
Paget's disease of bone {u} (Disease) is treated by {v} (Compound) Zoledronic acid
Zoledronic acid {u} may lead to a major life threatening interaction when taken with {v} Iopromide
Etidronic acid {u} (Compound) upregulates {v} (Gene) PLSCR1
PLSCR1 {u} (Gene) is upregulated by {v} (Compound) Bacitracin
Bacitracin {u} may lead to a major life threatening interaction when taken with {v} Iopromide
Etidronic acid {u} (Compound) upregulates {v} (Gene) CDK6
CDK6 {u} (Gene) is upregulated by {v} (Compound) Pindolol
Pindolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iopromide
Etidronic acid {u} (Compound) upregulates {v} (Gene) ABCC5
ABCC5 {u} (Gene) is bound by {v} (Compound) Cisplatin
Cisplatin {u} may lead to a major life threatening interaction when taken with {v} Iopromide
Etidronic acid (Compound) resembles Zoledronic acid (Compound) and Zoledronic acid may lead to a major life threatening interaction when taken with Iopromide
Etidronic acid (Compound) resembles Zoledronic acid (Compound) and Zoledronic acid may cause a moderate interaction that could exacerbate diseases when taken with Clofarabine and Clofarabine may lead to a major life threatening interaction when taken with Iopromide
Etidronic acid (Compound) resembles Ibandronate (Compound) and Ibandronate may cause a moderate interaction that could exacerbate diseases when taken with Clofarabine and Clofarabine may lead to a major life threatening interaction when taken with Iopromide
Etidronic acid (Compound) resembles Risedronic acid (Compound) and Risedronic acid (Compound) resembles Pamidronic acid (Compound) and Pamidronic acid may lead to a major life threatening interaction when taken with Iopromide
Etidronic acid (Compound) resembles Zoledronic acid (Compound) and Zoledronic acid (Compound) resembles Ibandronate (Compound) and Ibandronate may lead to a major life threatening interaction when taken with Iopromide
Etidronic acid (Compound) resembles Clodronate (Compound) and Clodronate (Compound) resembles Zoledronic acid (Compound) and Zoledronic acid may lead to a major life threatening interaction when taken with Iopromide
Etidronic acid (Compound) treats Paget's disease of bone (Disease) and Paget's disease of bone (Disease) is treated by Zoledronic acid (Compound) and Zoledronic acid may lead to a major life threatening interaction when taken with Iopromide
Etidronic acid (Compound) upregulates PLSCR1 (Gene) and PLSCR1 (Gene) is upregulated by Bacitracin (Compound) and Bacitracin may lead to a major life threatening interaction when taken with Iopromide
Etidronic acid (Compound) upregulates CDK6 (Gene) and CDK6 (Gene) is upregulated by Pindolol (Compound) and Pindolol may cause a moderate interaction that could exacerbate diseases when taken with Iopromide
Etidronic acid (Compound) upregulates ABCC5 (Gene) and ABCC5 (Gene) is bound by Cisplatin (Compound) and Cisplatin may lead to a major life threatening interaction when taken with Iopromide