DDInter1867 DDInter834
A phenothiazine used as an antipsychotic agent and as an antiemetic.
Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. They are both quaternary ammonium compounds and long acting muscarinic antagonists. It is one of the most commonly prescribed anticholinergic medications.[A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the treatment of peptic ulcers.[A233570,L33090] Later research, taking advantage of the systemic distribution of muscarinic receptors through the body, found that glycopyrronium could also be used for reducing sweat gland, oral, airway, and gastric secretions; as well as reducing cardiac inhibitory reflexes; and reducing bronchoconstriction in COPD. Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications and is considered to have a wider therapeutic window than [tiotropium]. Glycopyrronium was originally granted FDA approval on 11 August 1961.
Triflupromazine {u} (Compound) binds {v} (Gene) CHRM2
CHRM2 {u} (Gene) is bound by {v} (Compound) Glycopyrronium
Triflupromazine {u} (Compound) resembles {v} (Compound) Alimemazine
Alimemazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Glycopyrronium
Triflupromazine {u} (Compound) resembles {v} (Compound) Promazine
Promazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Glycopyrronium
Triflupromazine {u} (Compound) binds {v} (Gene) CHRM2
CHRM2 {u} (Gene) is bound by {v} (Compound) Mepenzolate
Mepenzolate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Glycopyrronium
Triflupromazine {u} (Compound) resembles {v} (Compound) Alimemazine
Alimemazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mepenzolate
Mepenzolate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Glycopyrronium
Triflupromazine {u} (Compound) resembles {v} (Compound) Pipotiazine
Pipotiazine {u} (Compound) resembles {v} (Compound) Methotrimeprazine
Methotrimeprazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Glycopyrronium
Triflupromazine {u} (Compound) binds {v} (Gene) CHRM2
CHRM2 {u} (Gene) is bound by {v} (Compound) Oxybutynin
Oxybutynin {u} (Compound) resembles {v} (Compound) Glycopyrronium
Triflupromazine {u} (Compound) resembles {v} (Compound) Alimemazine
Alimemazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clidinium
Clidinium {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Glycopyrronium
Triflupromazine {u} (Compound) resembles {v} (Compound) Promazine
Promazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clidinium
Clidinium {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Glycopyrronium
Triflupromazine {u} (Compound) resembles {v} (Compound) Alimemazine
Alimemazine {u} (Compound) downregulates {v} (Gene) PDHX
PDHX {u} (Gene) is downregulated by {v} (Compound) Glycopyrronium
Triflupromazine (Compound) binds CHRM2 (Gene) and CHRM2 (Gene) is bound by Glycopyrronium (Compound)
Triflupromazine (Compound) resembles Alimemazine (Compound) and Alimemazine may cause a moderate interaction that could exacerbate diseases when taken with Glycopyrronium
Triflupromazine (Compound) resembles Promazine (Compound) and Promazine may cause a moderate interaction that could exacerbate diseases when taken with Glycopyrronium
Triflupromazine (Compound) binds CHRM2 (Gene) and CHRM2 (Gene) is bound by Mepenzolate (Compound) and Mepenzolate may cause a moderate interaction that could exacerbate diseases when taken with Glycopyrronium
Triflupromazine (Compound) resembles Alimemazine (Compound) and Alimemazine may cause a moderate interaction that could exacerbate diseases when taken with Mepenzolate and Mepenzolate may cause a moderate interaction that could exacerbate diseases when taken with Glycopyrronium
Triflupromazine (Compound) resembles Pipotiazine (Compound) and Pipotiazine (Compound) resembles Methotrimeprazine (Compound) and Methotrimeprazine may cause a moderate interaction that could exacerbate diseases when taken with Glycopyrronium
Triflupromazine (Compound) binds CHRM2 (Gene) and CHRM2 (Gene) is bound by Oxybutynin (Compound) and Oxybutynin (Compound) resembles Glycopyrronium (Compound)
Triflupromazine (Compound) resembles Alimemazine (Compound) and Alimemazine may cause a moderate interaction that could exacerbate diseases when taken with Clidinium and Clidinium may cause a moderate interaction that could exacerbate diseases when taken with Glycopyrronium
Triflupromazine (Compound) resembles Promazine (Compound) and Promazine may cause a moderate interaction that could exacerbate diseases when taken with Clidinium and Clidinium may cause a moderate interaction that could exacerbate diseases when taken with Glycopyrronium
Triflupromazine (Compound) resembles Alimemazine (Compound) and Alimemazine (Compound) downregulates PDHX (Gene) and PDHX (Gene) is downregulated by Glycopyrronium (Compound)