DDInter1382 DDInter981
Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first dose of a course of chemotherapy and is the only drug of its class approved for this use by the U.S. Food and Drug Administration. As of 2008, it is the most recent 5-HT3 antagonist to enter clinical use.
Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor. It is used in the treatment of major depression, dysthymic disorder, atypical disorder, panic disorder and the phobic disorders. It was first introduced by Roche pharmaceuticals, further developed by Validus pharms Inc and first FDA approved as a prescription drug on July 1st, 1959.
Palonosetron {u} (Compound) causes {v} (Side Effect) Amblyopia
Amblyopia {u} (Side Effect) is caused by {v} (Compound) Isocarboxazid
Palonosetron {u} (Compound) causes {v} (Side Effect) Somnolence
Somnolence {u} (Side Effect) is caused by {v} (Compound) Lacosamide
Lacosamide {u} (Compound) resembles {v} (Compound) Isocarboxazid
Palonosetron {u} may lead to a major life threatening interaction when taken with {v} Phenelzine
Phenelzine {u} (Compound) resembles {v} (Compound) Phenacemide
Phenacemide {u} (Compound) resembles {v} (Compound) Isocarboxazid
Palonosetron {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Metamfetamine
Metamfetamine {u} (Compound) resembles {v} (Compound) Isocarboxazid
Palonosetron {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lisdexamfetamine
Lisdexamfetamine {u} (Compound) resembles {v} (Compound) Phenacemide
Phenacemide {u} (Compound) resembles {v} (Compound) Isocarboxazid
Palonosetron {u} may lead to a major life threatening interaction when taken with {v} Hydroxychloroquine
Hydroxychloroquine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenacemide
Phenacemide {u} (Compound) resembles {v} (Compound) Isocarboxazid
Palonosetron {u} may lead to a major life threatening interaction when taken with {v} Phenelzine
Phenelzine {u} (Compound) resembles {v} (Compound) Benzyl alcohol
Benzyl alcohol {u} (Compound) resembles {v} (Compound) Isocarboxazid
Palonosetron {u} may lead to a major life threatening interaction when taken with {v} Hydroxychloroquine
Hydroxychloroquine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lacosamide
Lacosamide {u} (Compound) resembles {v} (Compound) Isocarboxazid
Palonosetron {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lisdexamfetamine
Lisdexamfetamine {u} (Compound) resembles {v} (Compound) Metamfetamine
Metamfetamine {u} (Compound) resembles {v} (Compound) Isocarboxazid
Palonosetron {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Morphine
Morphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenacemide
Phenacemide {u} (Compound) resembles {v} (Compound) Isocarboxazid
Palonosetron (Compound) causes Amblyopia (Side Effect) and Amblyopia (Side Effect) is caused by Isocarboxazid (Compound)
Palonosetron (Compound) causes Somnolence (Side Effect) and Somnolence (Side Effect) is caused by Lacosamide (Compound) and Lacosamide (Compound) resembles Isocarboxazid (Compound)
Palonosetron may lead to a major life threatening interaction when taken with Phenelzine and Phenelzine (Compound) resembles Phenacemide (Compound) and Phenacemide (Compound) resembles Isocarboxazid (Compound)
Palonosetron (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Metamfetamine (Compound) and Metamfetamine (Compound) resembles Isocarboxazid (Compound)
Palonosetron may cause a moderate interaction that could exacerbate diseases when taken with Lisdexamfetamine and Lisdexamfetamine (Compound) resembles Phenacemide (Compound) and Phenacemide (Compound) resembles Isocarboxazid (Compound)
Palonosetron may lead to a major life threatening interaction when taken with Hydroxychloroquine and Hydroxychloroquine may cause a moderate interaction that could exacerbate diseases when taken with Phenacemide and Phenacemide (Compound) resembles Isocarboxazid (Compound)
Palonosetron may lead to a major life threatening interaction when taken with Phenelzine and Phenelzine (Compound) resembles Benzyl alcohol (Compound) and Benzyl alcohol (Compound) resembles Isocarboxazid (Compound)
Palonosetron may lead to a major life threatening interaction when taken with Hydroxychloroquine and Hydroxychloroquine may cause a moderate interaction that could exacerbate diseases when taken with Lacosamide and Lacosamide (Compound) resembles Isocarboxazid (Compound)
Palonosetron may cause a moderate interaction that could exacerbate diseases when taken with Lisdexamfetamine and Lisdexamfetamine (Compound) resembles Metamfetamine (Compound) and Metamfetamine (Compound) resembles Isocarboxazid (Compound)
Palonosetron may cause a moderate interaction that could exacerbate diseases when taken with Morphine and Morphine may cause a moderate interaction that could exacerbate diseases when taken with Phenacemide and Phenacemide (Compound) resembles Isocarboxazid (Compound)