DDInter1642 DDInter1425
Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.
A potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
Pentostatin {u} (Compound) resembles {v} (Compound) Trifluridine
Pentostatin {u} (Compound) resembles {v} (Compound) Azacitidine
Pentostatin {u} (Compound) treats {v} (Disease) hematologic cancer
Pentostatin {u} (Compound) binds {v} (Gene) ADA
Pentostatin {u} (Compound) is included by {v} (Pharmacologic Class) Nucleic Acid Synthesis Inhibitors
Pentostatin {u} (Compound) causes {v} (Side Effect) Foetor hepaticus
Pentostatin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Enoxacin
Pentostatin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ofloxacin
Pentostatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Aldesleukin
Pentostatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Hydroxyurea
Pentostatin (Compound) resembles Trifluridine (Compound)
Pentostatin (Compound) resembles Azacitidine (Compound)
Pentostatin (Compound) treats hematologic cancer (Disease)
Pentostatin (Compound) binds ADA (Gene)
Pentostatin (Compound) is included by Nucleic Acid Synthesis Inhibitors (Pharmacologic Class)
Pentostatin (Compound) causes Foetor hepaticus (Side Effect)
Pentostatin may cause a minor interaction that can limit clinical effects when taken with Enoxacin
Pentostatin may cause a minor interaction that can limit clinical effects when taken with Ofloxacin
Pentostatin may cause a moderate interaction that could exacerbate diseases when taken with Aldesleukin
Pentostatin may cause a moderate interaction that could exacerbate diseases when taken with Hydroxyurea