DDInter842 DDInter1016
Grepafloxacin is an oral broad-spectrum quinoline antibacterial agent used to treat bacterial infections. Due to the QTc-prolonging potential, as indicated by the changes in the QT interval on the electrocardiogram, and the risk for cardiovascular adverse events, grepafloxacin was withdrawn in the United States.
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose]. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. [sucrose]). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in patients with cirrhosis.[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.
Grepafloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Fludarabine
Grepafloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Denileukin diftitox
Grepafloxacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Semaglutide
Grepafloxacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Caffeine
Grepafloxacin {u} may lead to a major life threatening interaction when taken with {v} Encorafenib
Grepafloxacin {u} may lead to a major life threatening interaction when taken with {v} Insulin glargine
Grepafloxacin may cause a minor interaction that can limit clinical effects when taken with Fludarabine
Grepafloxacin may cause a minor interaction that can limit clinical effects when taken with Denileukin diftitox
Grepafloxacin may cause a moderate interaction that could exacerbate diseases when taken with Semaglutide
Grepafloxacin may cause a moderate interaction that could exacerbate diseases when taken with Caffeine
Grepafloxacin may lead to a major life threatening interaction when taken with Encorafenib
Grepafloxacin may lead to a major life threatening interaction when taken with Insulin glargine