DDInter21 DDInter624
An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.
Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1. For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with zidovudine or tenofovir is the preferred NNRTI-based regimen. Efavirenz is also used in combination with other antiretroviral agents as part of an expanded postexposure prophylaxis regimen to prevent HIV transmission for those exposed to materials associated with a high risk for HIV transmission.
Acitretin {u} (Compound) causes {v} (Side Effect) Hepatitis
Hepatitis {u} (Side Effect) is caused by {v} (Compound) Efavirenz
Acitretin {u} (Compound) resembles {v} (Compound) Vitamin A
Vitamin A {u} (Compound) upregulates {v} (Gene) IKBKB
IKBKB {u} (Gene) is upregulated by {v} (Compound) Efavirenz
Acitretin {u} (Compound) resembles {v} (Compound) Alitretinoin
Alitretinoin {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Efavirenz
Acitretin {u} (Compound) resembles {v} (Compound) Vitamin A
Vitamin A {u} (Compound) downregulates {v} (Gene) OXA1L
OXA1L {u} (Gene) is downregulated by {v} (Compound) Efavirenz
Acitretin {u} may lead to a major life threatening interaction when taken with {v} Isotretinoin
Isotretinoin {u} (Compound) upregulates {v} (Gene) IKBKB
IKBKB {u} (Gene) is upregulated by {v} (Compound) Efavirenz
Acitretin {u} (Compound) resembles {v} (Compound) Vitamin A
Vitamin A {u} (Compound) causes {v} (Side Effect) Hypersensitivity
Hypersensitivity {u} (Side Effect) is caused by {v} (Compound) Efavirenz
Acitretin {u} may lead to a major life threatening interaction when taken with {v} Isotretinoin
Isotretinoin {u} (Compound) downregulates {v} (Gene) CCDC86
CCDC86 {u} (Gene) is downregulated by {v} (Compound) Efavirenz
Acitretin {u} (Compound) binds {v} (Gene) RBP1
RBP1 {u} (Gene) is regulated by {v} (Gene) IKBKB
IKBKB {u} (Gene) is upregulated by {v} (Compound) Efavirenz
Acitretin {u} may lead to a major life threatening interaction when taken with {v} Isotretinoin
Isotretinoin {u} (Compound) causes {v} (Side Effect) Hepatitis
Hepatitis {u} (Side Effect) is caused by {v} (Compound) Efavirenz
Acitretin {u} (Compound) binds {v} (Gene) RXRA
RXRA {u} (Gene) regulates {v} (Gene) PFN1
PFN1 {u} (Gene) is downregulated by {v} (Compound) Efavirenz
Acitretin (Compound) causes Hepatitis (Side Effect) and Hepatitis (Side Effect) is caused by Efavirenz (Compound)
Acitretin (Compound) resembles Vitamin A (Compound) and Vitamin A (Compound) upregulates IKBKB (Gene) and IKBKB (Gene) is upregulated by Efavirenz (Compound)
Acitretin (Compound) resembles Alitretinoin (Compound) and Alitretinoin (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Efavirenz (Compound)
Acitretin (Compound) resembles Vitamin A (Compound) and Vitamin A (Compound) downregulates OXA1L (Gene) and OXA1L (Gene) is downregulated by Efavirenz (Compound)
Acitretin may lead to a major life threatening interaction when taken with Isotretinoin and Isotretinoin (Compound) upregulates IKBKB (Gene) and IKBKB (Gene) is upregulated by Efavirenz (Compound)
Acitretin (Compound) resembles Vitamin A (Compound) and Vitamin A (Compound) causes Hypersensitivity (Side Effect) and Hypersensitivity (Side Effect) is caused by Efavirenz (Compound)
Acitretin may lead to a major life threatening interaction when taken with Isotretinoin and Isotretinoin (Compound) downregulates CCDC86 (Gene) and CCDC86 (Gene) is downregulated by Efavirenz (Compound)
Acitretin (Compound) binds RBP1 (Gene) and RBP1 (Gene) is regulated by IKBKB (Gene) and IKBKB (Gene) is upregulated by Efavirenz (Compound)
Acitretin may lead to a major life threatening interaction when taken with Isotretinoin and Isotretinoin (Compound) causes Hepatitis (Side Effect) and Hepatitis (Side Effect) is caused by Efavirenz (Compound)
Acitretin (Compound) binds RXRA (Gene) and RXRA (Gene) regulates PFN1 (Gene) and PFN1 (Gene) is downregulated by Efavirenz (Compound)