DDInter843 DDInter1747
An antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections.
Tasimelteon is a selective dual melatonin receptor agonist indicated for the treatment of Non-24-Hour Sleep-Wake Disorder (N24HSWD). Occurring commonly in blind individuals without light perception, this condition is often characterized by periods of night-time insomnia and day-time sleepiness. In blind individuals, a lack of light stimulation causes an extension of the 24-hour circadian cycle and can lead to progressively delayed sleep onset. By activating melatonin receptors MT1 and MT2 in the suprachiasmatic nucleus of the brain, tasimelteon has been shown to improve sleep by resynchronizing the circadian rhythm through its "non-photic" mechanism. Tasimelteon is currently the only drug available for the treatment of N24HSWD and was granted orphan drug status by the FDA in 2010.
Griseofulvin {u} (Compound) binds {v} (Gene) KRT12
Griseofulvin {u} (Compound) is included by {v} (Pharmacologic Class) Decreased Mitosis
Griseofulvin {u} (Compound) downregulates {v} (Gene) CCDC86
Griseofulvin {u} (Compound) causes {v} (Side Effect) Neuropathy peripheral
Griseofulvin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Bortezomib
Griseofulvin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Dolutegravir
Griseofulvin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Naloxegol
Griseofulvin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mirtazapine
Griseofulvin {u} may lead to a major life threatening interaction when taken with {v} Norgestimate
Griseofulvin {u} may lead to a major life threatening interaction when taken with {v} Etonogestrel
Griseofulvin (Compound) binds KRT12 (Gene)
Griseofulvin (Compound) is included by Decreased Mitosis (Pharmacologic Class)
Griseofulvin (Compound) downregulates CCDC86 (Gene)
Griseofulvin (Compound) causes Neuropathy peripheral (Side Effect)
Griseofulvin may cause a minor interaction that can limit clinical effects when taken with Bortezomib
Griseofulvin may cause a minor interaction that can limit clinical effects when taken with Dolutegravir
Griseofulvin may cause a moderate interaction that could exacerbate diseases when taken with Naloxegol
Griseofulvin may cause a moderate interaction that could exacerbate diseases when taken with Mirtazapine
Griseofulvin may lead to a major life threatening interaction when taken with Norgestimate
Griseofulvin may lead to a major life threatening interaction when taken with Etonogestrel