DDInter92 DDInter1376
Amyl Nitrite is an antihypertensive medicine. Amyl nitrite is employed medically to treat heart diseases such as angina and to treat cyanide poisoning. Its use as a prescription medicine comes from its ability to lower blood pressure. As an inhalant, it also has psychoactive effect which has led to illegal drug use.
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26, 2020.[L12573,L12582] The US approval was followed by the approval in Canada on October 2, 2020. In November 2021, ozanimod was also approved by the European Commission for the treatment of adults with relapsing remitting multiple sclerosis.[L39377,L39382] MS is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Inflammatory bowel disease also a chronic inflammatory condition and can cause persistent abdominal pain, diarrhea, bloody stools, and vomiting. In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard in MS therapy. Studies involving patients with inflammatory bowel disease have also shown promising results.[A189318,A189342]
Amyl Nitrite {u} (Compound) binds {v} (Gene) ALDH2
Amyl Nitrite {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Buspirone
Amyl Nitrite {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oliceridine
Amyl Nitrite {u} may lead to a major life threatening interaction when taken with {v} Vardenafil
Amyl Nitrite {u} may lead to a major life threatening interaction when taken with {v} Riociguat
Amyl Nitrite (Compound) binds ALDH2 (Gene)
Amyl Nitrite may cause a moderate interaction that could exacerbate diseases when taken with Buspirone
Amyl Nitrite may cause a moderate interaction that could exacerbate diseases when taken with Oliceridine
Amyl Nitrite may lead to a major life threatening interaction when taken with Vardenafil
Amyl Nitrite may lead to a major life threatening interaction when taken with Riociguat