DDInter1158 DDInter1908
An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease. Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical agent. Throughout the late seventies and the eighties, important research initiatives developed stable mesalazine formulations like the eudragit-S coating of Asacol brand mesalazine and the Pentasa brand's encapsulation of mesalazine within microgranules. In the present day, contemporary research regarding novel methods to stabilize mesalazine continues and interest in the agent's capacity to decrease inflammatory activity and subsequently potentially reduce the risk of colorectal cancer in conditions like ulcerative colitis is maintained.[A174019,A174022]
Valaciclovir (valacyclovir), also known as _Valtrex_, is an antiviral drug that has been used to manage and treat various herpes infections for more than 2 decades. It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline . Valacyclovir is the L-valine ester of aciclovir. It is a member of the purine (guanine) nucleoside analog drug class . This class of drugs forms an important part of hepatitis, HIV, and cytomegalovirus drug regimens . One major use of valacyclovir is the treatment of genital herpes episodes or outbreaks. Genital herpes is a frequently diagnosed sexually transmitted disease which currently affects more than 400 million individuals worldwide. It is caused by infection with the herpes simplex virus (HSV). Infection with this virus is lifelong with periodic episodes of reactivation .
Mesalazine {u} (Compound) causes {v} (Side Effect) Stomatitis
Stomatitis {u} (Side Effect) is caused by {v} (Compound) Valaciclovir
Mesalazine {u} (Compound) resembles {v} (Compound) Olsalazine
Olsalazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Valaciclovir
Mesalazine {u} (Compound) causes {v} (Side Effect) Stomatitis
Stomatitis {u} (Side Effect) is caused by {v} (Compound) Ganciclovir
Ganciclovir {u} (Compound) resembles {v} (Compound) Valaciclovir
Mesalazine {u} (Compound) causes {v} (Side Effect) Rectal disorder
Rectal disorder {u} (Side Effect) is caused by {v} (Compound) Mycophenolic acid
Mycophenolic acid {u} may cause a minor interaction that can limit clinical effects when taken with {v} Valaciclovir
Mesalazine {u} (Compound) causes {v} (Side Effect) Menorrhagia
Menorrhagia {u} (Side Effect) is caused by {v} (Compound) Clofarabine
Clofarabine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Valaciclovir
Mesalazine {u} (Compound) resembles {v} (Compound) Olsalazine
Olsalazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acyclovir
Acyclovir {u} (Compound) resembles {v} (Compound) Valaciclovir
Mesalazine {u} (Compound) causes {v} (Side Effect) Rectal disorder
Rectal disorder {u} (Side Effect) is caused by {v} (Compound) Sirolimus
Sirolimus {u} may lead to a major life threatening interaction when taken with {v} Valaciclovir
Mesalazine {u} (Compound) causes {v} (Side Effect) Abdominal discomfort
Abdominal discomfort {u} (Side Effect) is caused by {v} (Compound) Cladribine
Cladribine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Valaciclovir
Mesalazine {u} (Compound) resembles {v} (Compound) Olsalazine
Olsalazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pentamidine
Pentamidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Valaciclovir
Mesalazine {u} (Compound) causes {v} (Side Effect) Erythema multiforme
Erythema multiforme {u} (Side Effect) is caused by {v} (Compound) Cimetidine
Cimetidine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Valaciclovir
Mesalazine (Compound) causes Stomatitis (Side Effect) and Stomatitis (Side Effect) is caused by Valaciclovir (Compound)
Mesalazine (Compound) resembles Olsalazine (Compound) and Olsalazine may cause a moderate interaction that could exacerbate diseases when taken with Valaciclovir
Mesalazine (Compound) causes Stomatitis (Side Effect) and Stomatitis (Side Effect) is caused by Ganciclovir (Compound) and Ganciclovir (Compound) resembles Valaciclovir (Compound)
Mesalazine (Compound) causes Rectal disorder (Side Effect) and Rectal disorder (Side Effect) is caused by Mycophenolic acid (Compound) and Mycophenolic acid may cause a minor interaction that can limit clinical effects when taken with Valaciclovir
Mesalazine (Compound) causes Menorrhagia (Side Effect) and Menorrhagia (Side Effect) is caused by Clofarabine (Compound) and Clofarabine may cause a moderate interaction that could exacerbate diseases when taken with Valaciclovir
Mesalazine (Compound) resembles Olsalazine (Compound) and Olsalazine may cause a moderate interaction that could exacerbate diseases when taken with Acyclovir and Acyclovir (Compound) resembles Valaciclovir (Compound)
Mesalazine (Compound) causes Rectal disorder (Side Effect) and Rectal disorder (Side Effect) is caused by Sirolimus (Compound) and Sirolimus may lead to a major life threatening interaction when taken with Valaciclovir
Mesalazine (Compound) causes Abdominal discomfort (Side Effect) and Abdominal discomfort (Side Effect) is caused by Cladribine (Compound) and Cladribine may cause a moderate interaction that could exacerbate diseases when taken with Valaciclovir
Mesalazine (Compound) resembles Olsalazine (Compound) and Olsalazine may cause a moderate interaction that could exacerbate diseases when taken with Pentamidine and Pentamidine may cause a moderate interaction that could exacerbate diseases when taken with Valaciclovir
Mesalazine (Compound) causes Erythema multiforme (Side Effect) and Erythema multiforme (Side Effect) is caused by Cimetidine (Compound) and Cimetidine may cause a minor interaction that can limit clinical effects when taken with Valaciclovir