DDInter604 DDInter1501
Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with [Ethinyl estradiol]. Most recently, it was approved by both Health Canada and the FDA in combination with [Estetrol] as an oral contraceptive therapy.[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to control acne and premenstrual dysphoric disorder (PMDD). Drospirenone has been the subject of widespread safety concern due to the possibility of an increased risk of venous thromboembolism associated with its use.[A182543,A182552] In 2012, however, a safety statement by the FDA concluded that the increase in the risk of thromboembolism resulting from the use of drospirenone remains unclear, as studies regarding this risk are conflicting. Some studies have demonstrated a significantly increased risk and some demonstrating no risk of thrombo
Potassium perchlorate is an inorganic salt with the chemical formula KClO4. It is a strong oxidizer with the lowest solubility of the alkali metal perchlorates. Potassium is most commonly used in flares and automobile airbags . The use of potassium perchlorate as a component in sealing gaskets for food containers has been revoked by the FDA following the use being abandoned by the industry . Potassium perchlorate acts as a competitive inhibitor of iodine uptake by the thyroid gland and attenuates the production of the thyroid hormone. Thus the use of potassium perchlorate has been extensive for hyperthyroidism during the last 50 years, particularly in the late 1950s and early 1960s . The therapeutic use of potassium perchlorate in thyroid disorders has been ceased due to a high risk for developing aplastic anemia and nephrotic syndrome .
Drospirenone {u} (Compound) resembles {v} (Compound) Spironolactone
Spironolactone {u} may lead to a major life threatening interaction when taken with {v} Potassium perchlorate
Drospirenone {u} (Compound) resembles {v} (Compound) Spironolactone
Spironolactone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Flurbiprofen
Flurbiprofen {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Potassium perchlorate
Drospirenone {u} (Compound) resembles {v} (Compound) Progesterone
Progesterone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Insulin glargine
Insulin glargine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Potassium perchlorate
Drospirenone {u} (Compound) resembles {v} (Compound) Progesterone
Progesterone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Insulin glulisine
Insulin glulisine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Potassium perchlorate
Drospirenone {u} (Compound) resembles {v} (Compound) Eplerenone
Eplerenone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Diclofenac
Diclofenac {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Potassium perchlorate
Drospirenone {u} (Compound) resembles {v} (Compound) Methyltestosterone
Methyltestosterone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Insulin glargine
Insulin glargine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Potassium perchlorate
Drospirenone {u} (Compound) resembles {v} (Compound) Spironolactone
Spironolactone {u} (Compound) resembles {v} (Compound) Eplerenone
Eplerenone {u} may lead to a major life threatening interaction when taken with {v} Potassium perchlorate
Drospirenone {u} (Compound) resembles {v} (Compound) Progesterone
Progesterone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Insulin degludec
Insulin degludec {u} may cause a minor interaction that can limit clinical effects when taken with {v} Potassium perchlorate
Drospirenone {u} (Compound) resembles {v} (Compound) Eplerenone
Eplerenone {u} (Compound) resembles {v} (Compound) Spironolactone
Spironolactone {u} may lead to a major life threatening interaction when taken with {v} Potassium perchlorate
Drospirenone {u} (Compound) resembles {v} (Compound) Norethisterone
Norethisterone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Insulin glulisine
Insulin glulisine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Potassium perchlorate
Drospirenone (Compound) resembles Spironolactone (Compound) and Spironolactone may lead to a major life threatening interaction when taken with Potassium perchlorate
Drospirenone (Compound) resembles Spironolactone (Compound) and Spironolactone may cause a moderate interaction that could exacerbate diseases when taken with Flurbiprofen and Flurbiprofen may cause a moderate interaction that could exacerbate diseases when taken with Potassium perchlorate
Drospirenone (Compound) resembles Progesterone (Compound) and Progesterone may cause a moderate interaction that could exacerbate diseases when taken with Insulin glargine and Insulin glargine may cause a minor interaction that can limit clinical effects when taken with Potassium perchlorate
Drospirenone (Compound) resembles Progesterone (Compound) and Progesterone may cause a moderate interaction that could exacerbate diseases when taken with Insulin glulisine and Insulin glulisine may cause a minor interaction that can limit clinical effects when taken with Potassium perchlorate
Drospirenone (Compound) resembles Eplerenone (Compound) and Eplerenone may cause a moderate interaction that could exacerbate diseases when taken with Diclofenac and Diclofenac may cause a moderate interaction that could exacerbate diseases when taken with Potassium perchlorate
Drospirenone (Compound) resembles Methyltestosterone (Compound) and Methyltestosterone may cause a moderate interaction that could exacerbate diseases when taken with Insulin glargine and Insulin glargine may cause a minor interaction that can limit clinical effects when taken with Potassium perchlorate
Drospirenone (Compound) resembles Spironolactone (Compound) and Spironolactone (Compound) resembles Eplerenone (Compound) and Eplerenone may lead to a major life threatening interaction when taken with Potassium perchlorate
Drospirenone (Compound) resembles Progesterone (Compound) and Progesterone may cause a moderate interaction that could exacerbate diseases when taken with Insulin degludec and Insulin degludec may cause a minor interaction that can limit clinical effects when taken with Potassium perchlorate
Drospirenone (Compound) resembles Eplerenone (Compound) and Eplerenone (Compound) resembles Spironolactone (Compound) and Spironolactone may lead to a major life threatening interaction when taken with Potassium perchlorate
Drospirenone (Compound) resembles Norethisterone (Compound) and Norethisterone may cause a moderate interaction that could exacerbate diseases when taken with Insulin glulisine and Insulin glulisine may cause a minor interaction that can limit clinical effects when taken with Potassium perchlorate