DDInter580 DDInter416
Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration (FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation and flutter, and for the chemical cardioversion to sinus rhythm from atrial fibrillation and flutter.
This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the _imidazole_ category of _azole_ antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers . The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain widespread acceptance for the treatment of mycotic outbreaks such as vaginal yeast infections as well as athlete's foot .
Dofetilide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Loperamide
Loperamide {u} (Compound) resembles {v} (Compound) Clotrimazole
Dofetilide {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Clotrimazole
Dofetilide {u} (Compound) causes {v} (Side Effect) Pain
Pain {u} (Side Effect) is caused by {v} (Compound) Clotrimazole
Dofetilide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Loperamide
Loperamide {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methadone
Methadone {u} (Compound) resembles {v} (Compound) Clotrimazole
Dofetilide {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Methadone
Methadone {u} (Compound) resembles {v} (Compound) Clotrimazole
Dofetilide {u} (Compound) causes {v} (Side Effect) Pain
Pain {u} (Side Effect) is caused by {v} (Compound) Methadone
Methadone {u} (Compound) resembles {v} (Compound) Clotrimazole
Dofetilide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Loperamide
Loperamide {u} (Compound) resembles {v} (Compound) Diphenidol
Diphenidol {u} (Compound) resembles {v} (Compound) Clotrimazole
Dofetilide {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Sulfinpyrazone
Sulfinpyrazone {u} (Compound) resembles {v} (Compound) Clotrimazole
Dofetilide {u} (Compound) causes {v} (Side Effect) Pain
Pain {u} (Side Effect) is caused by {v} (Compound) Darifenacin
Darifenacin {u} (Compound) resembles {v} (Compound) Clotrimazole
Dofetilide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Loperamide
Loperamide {u} (Compound) resembles {v} (Compound) Clofedanol
Clofedanol {u} (Compound) resembles {v} (Compound) Clotrimazole
Dofetilide may cause a moderate interaction that could exacerbate diseases when taken with Loperamide and Loperamide (Compound) resembles Clotrimazole (Compound)
Dofetilide (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Clotrimazole (Compound)
Dofetilide (Compound) causes Pain (Side Effect) and Pain (Side Effect) is caused by Clotrimazole (Compound)
Dofetilide may cause a moderate interaction that could exacerbate diseases when taken with Loperamide and Loperamide (Compound) resembles Methadone (Compound) and Loperamide may cause a moderate interaction that could exacerbate diseases when taken with Methadone and Methadone (Compound) resembles Clotrimazole (Compound)
Dofetilide (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Methadone (Compound) and Methadone (Compound) resembles Clotrimazole (Compound)
Dofetilide (Compound) causes Pain (Side Effect) and Pain (Side Effect) is caused by Methadone (Compound) and Methadone (Compound) resembles Clotrimazole (Compound)
Dofetilide may cause a moderate interaction that could exacerbate diseases when taken with Loperamide and Loperamide (Compound) resembles Diphenidol (Compound) and Diphenidol (Compound) resembles Clotrimazole (Compound)
Dofetilide (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Sulfinpyrazone (Compound) and Sulfinpyrazone (Compound) resembles Clotrimazole (Compound)
Dofetilide (Compound) causes Pain (Side Effect) and Pain (Side Effect) is caused by Darifenacin (Compound) and Darifenacin (Compound) resembles Clotrimazole (Compound)
Dofetilide may cause a moderate interaction that could exacerbate diseases when taken with Loperamide and Loperamide (Compound) resembles Clofedanol (Compound) and Clofedanol (Compound) resembles Clotrimazole (Compound)