DDInter1826 DDInter704
A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and not on the mTORC2 protein.
Tolazamide {u} (Compound) upregulates {v} (Gene) JADE2
JADE2 {u} (Gene) is downregulated by {v} (Compound) Everolimus
Tolazamide {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Everolimus
Tolazamide {u} (Compound) upregulates {v} (Gene) JADE2
JADE2 {u} (Gene) is regulated by {v} (Gene) MTOR
MTOR {u} (Gene) is bound by {v} (Compound) Everolimus
Tolazamide {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Pimecrolimus
Pimecrolimus {u} (Compound) resembles {v} (Compound) Everolimus
Tolazamide {u} (Compound) causes {v} (Side Effect) Asthenia
Asthenia {u} (Side Effect) is caused by {v} (Compound) Temsirolimus
Temsirolimus {u} (Compound) resembles {v} (Compound) Everolimus
Tolazamide {u} (Compound) resembles {v} (Compound) Tolbutamide
Tolbutamide {u} (Compound) upregulates {v} (Gene) SUV39H1
SUV39H1 {u} (Gene) is downregulated by {v} (Compound) Everolimus
Tolazamide {u} (Compound) upregulates {v} (Gene) JADE2
JADE2 {u} (Gene) regulates {v} (Gene) PNP
PNP {u} (Gene) is upregulated by {v} (Compound) Everolimus
Tolazamide {u} (Compound) resembles {v} (Compound) Sulfacetamide
Sulfacetamide {u} (Compound) upregulates {v} (Gene) HLA-DMA
HLA-DMA {u} (Gene) is upregulated by {v} (Compound) Everolimus
Tolazamide {u} (Compound) resembles {v} (Compound) Tolbutamide
Tolbutamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Everolimus
Tolazamide {u} (Compound) upregulates {v} (Gene) JADE2
JADE2 {u} (Gene) is regulated by {v} (Gene) SIRT1
SIRT1 {u} (Gene) is upregulated by {v} (Compound) Everolimus
Tolazamide (Compound) upregulates JADE2 (Gene) and JADE2 (Gene) is downregulated by Everolimus (Compound)
Tolazamide (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Everolimus (Compound)
Tolazamide (Compound) upregulates JADE2 (Gene) and JADE2 (Gene) is regulated by MTOR (Gene) and MTOR (Gene) is bound by Everolimus (Compound)
Tolazamide (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Pimecrolimus (Compound) and Pimecrolimus (Compound) resembles Everolimus (Compound)
Tolazamide (Compound) causes Asthenia (Side Effect) and Asthenia (Side Effect) is caused by Temsirolimus (Compound) and Temsirolimus (Compound) resembles Everolimus (Compound)
Tolazamide (Compound) resembles Tolbutamide (Compound) and Tolbutamide (Compound) upregulates SUV39H1 (Gene) and SUV39H1 (Gene) is downregulated by Everolimus (Compound)
Tolazamide (Compound) upregulates JADE2 (Gene) and JADE2 (Gene) regulates PNP (Gene) and PNP (Gene) is upregulated by Everolimus (Compound)
Tolazamide (Compound) resembles Sulfacetamide (Compound) and Sulfacetamide (Compound) upregulates HLA-DMA (Gene) and HLA-DMA (Gene) is upregulated by Everolimus (Compound)
Tolazamide (Compound) resembles Tolbutamide (Compound) and Tolbutamide may cause a moderate interaction that could exacerbate diseases when taken with Sirolimus and Sirolimus (Compound) resembles Everolimus (Compound)
Tolazamide (Compound) upregulates JADE2 (Gene) and JADE2 (Gene) is regulated by SIRT1 (Gene) and SIRT1 (Gene) is upregulated by Everolimus (Compound)