DDInter1464 DDInter1676
Picosulfuric acid is found in laxative products. Sodium picosulfate is a used to treat constipation or induce colon cleansing to prepare the large bowels before colonoscopy or surgery. The combination product containing sodium picosulfate and magnesium citrate was introduced to the Canadian market in 2005 and has been used in European countries for many years.
Siponimod, also known as _Mayzent_, by Novartis, is a new drug formulated for the management of Multiple Sclerosis (MS). It was approved by the FDA on March 26, 2019 and by Health Canada on February 20, 2020. This drug is considered a _sphingosine-1-phosphate (S1P) receptor modulator_ and is thought to play a role in suppressing the central nervous system inflammation that is associated with MS [FDA label]. Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system that is chronic and inflammatory, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of life. Symptoms may include but are not limited to fatigue, gait changes, bowel or bladder dysfunction, abnormal muscle twitching, vision disturbance, and depressing or mood swings. MS is one of the most common causes of neurological disability in young adults and is found to occur more frequently in women than in men.[A176474,L5792]
Picosulfuric acid {u} may cause a minor interaction that can limit clinical effects when taken with {v} Digitoxin
Picosulfuric acid {u} may cause a minor interaction that can limit clinical effects when taken with {v} Methylcellulose
Picosulfuric acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Trimipramine
Picosulfuric acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Entrectinib
Picosulfuric acid {u} may lead to a major life threatening interaction when taken with {v} Sotalol
Picosulfuric acid may cause a minor interaction that can limit clinical effects when taken with Digitoxin
Picosulfuric acid may cause a minor interaction that can limit clinical effects when taken with Methylcellulose
Picosulfuric acid may cause a moderate interaction that could exacerbate diseases when taken with Trimipramine
Picosulfuric acid may cause a moderate interaction that could exacerbate diseases when taken with Entrectinib
Picosulfuric acid may lead to a major life threatening interaction when taken with Sotalol