DDInter364 DDInter383
Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor. Sulfonylureas also increase peripheral glucose utilization, decrease hepatic gluconeogenesis and may increase the number and sensitivity of insulin receptors. Sulfonylureas are associated with weight gain, though less so than insulin. Due to their mechanism of action, sulfonylureas may cause hypoglycemia and require consistent food intake to decrease this risk. The risk of hypoglycemia is increased in elderly, deb
Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.
Chlorpropamide {u} (Compound) binds {v} (Gene) SLC22A6
SLC22A6 {u} (Gene) is bound by {v} (Compound) Cinoxacin
Chlorpropamide {u} (Compound) causes {v} (Side Effect) Eosinophilia
Eosinophilia {u} (Side Effect) is caused by {v} (Compound) Cinoxacin
Chlorpropamide {u} (Compound) resembles {v} (Compound) Glipizide
Glipizide {u} may lead to a major life threatening interaction when taken with {v} Cinoxacin
Chlorpropamide {u} (Compound) resembles {v} (Compound) Glimepiride
Glimepiride {u} may lead to a major life threatening interaction when taken with {v} Cinoxacin
Chlorpropamide {u} (Compound) resembles {v} (Compound) Tolbutamide
Tolbutamide {u} may lead to a major life threatening interaction when taken with {v} Cinoxacin
Chlorpropamide {u} (Compound) binds {v} (Gene) SLC22A6
SLC22A6 {u} (Gene) is bound by {v} (Compound) Acetylsalicylic acid
Acetylsalicylic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cinoxacin
Chlorpropamide {u} (Compound) causes {v} (Side Effect) Eosinophilia
Eosinophilia {u} (Side Effect) is caused by {v} (Compound) Epirubicin
Epirubicin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cinoxacin
Chlorpropamide {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Idarubicin
Idarubicin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cinoxacin
Chlorpropamide {u} (Compound) resembles {v} (Compound) Glipizide
Glipizide {u} (Compound) causes {v} (Side Effect) Somnolence
Somnolence {u} (Side Effect) is caused by {v} (Compound) Cinoxacin
Chlorpropamide {u} (Compound) resembles {v} (Compound) Sulfacetamide
Sulfacetamide {u} (Compound) resembles {v} (Compound) Tolbutamide
Tolbutamide {u} may lead to a major life threatening interaction when taken with {v} Cinoxacin
Chlorpropamide (Compound) binds SLC22A6 (Gene) and SLC22A6 (Gene) is bound by Cinoxacin (Compound)
Chlorpropamide (Compound) causes Eosinophilia (Side Effect) and Eosinophilia (Side Effect) is caused by Cinoxacin (Compound)
Chlorpropamide (Compound) resembles Glipizide (Compound) and Glipizide may lead to a major life threatening interaction when taken with Cinoxacin
Chlorpropamide (Compound) resembles Glimepiride (Compound) and Glimepiride may lead to a major life threatening interaction when taken with Cinoxacin
Chlorpropamide (Compound) resembles Tolbutamide (Compound) and Tolbutamide may lead to a major life threatening interaction when taken with Cinoxacin
Chlorpropamide (Compound) binds SLC22A6 (Gene) and SLC22A6 (Gene) is bound by Acetylsalicylic acid (Compound) and Acetylsalicylic acid may cause a moderate interaction that could exacerbate diseases when taken with Cinoxacin
Chlorpropamide (Compound) causes Eosinophilia (Side Effect) and Eosinophilia (Side Effect) is caused by Epirubicin (Compound) and Epirubicin may cause a minor interaction that can limit clinical effects when taken with Cinoxacin
Chlorpropamide (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Idarubicin (Compound) and Idarubicin may cause a minor interaction that can limit clinical effects when taken with Cinoxacin
Chlorpropamide (Compound) resembles Glipizide (Compound) and Glipizide (Compound) causes Somnolence (Side Effect) and Somnolence (Side Effect) is caused by Cinoxacin (Compound)
Chlorpropamide (Compound) resembles Sulfacetamide (Compound) and Sulfacetamide (Compound) resembles Tolbutamide (Compound) and Tolbutamide may lead to a major life threatening interaction when taken with Cinoxacin