DDInter1809 DDInter1676
Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. It is also used in tablet form as a drug to treat hypertension. Timolol was first approved by the FDA in 1978. This drug is marketed by several manufacturers and is an effective agent for the management of conditions such as open-angle glaucoma and hypertension.
Siponimod, also known as _Mayzent_, by Novartis, is a new drug formulated for the management of Multiple Sclerosis (MS). It was approved by the FDA on March 26, 2019 and by Health Canada on February 20, 2020. This drug is considered a _sphingosine-1-phosphate (S1P) receptor modulator_ and is thought to play a role in suppressing the central nervous system inflammation that is associated with MS [FDA label]. Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system that is chronic and inflammatory, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of life. Symptoms may include but are not limited to fatigue, gait changes, bowel or bladder dysfunction, abnormal muscle twitching, vision disturbance, and depressing or mood swings. MS is one of the most common causes of neurological disability in young adults and is found to occur more frequently in women than in men.[A176474,L5792]
Timolol {u} (Compound) resembles {v} (Compound) Levobunolol
Timolol {u} (Compound) treats {v} (Disease) glaucoma
Timolol {u} (Compound) binds {v} (Gene) ADRB1
Timolol {u} (Compound) upregulates {v} (Gene) TCN1
Timolol {u} (Compound) downregulates {v} (Gene) PEG10
Timolol {u} (Compound) causes {v} (Side Effect) Affect lability
Timolol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium oxide
Timolol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Liothyronine
Timolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iopodic acid
Timolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Gadodiamide
Timolol (Compound) resembles Levobunolol (Compound)
Timolol (Compound) treats glaucoma (Disease)
Timolol (Compound) binds ADRB1 (Gene)
Timolol (Compound) upregulates TCN1 (Gene)
Timolol (Compound) downregulates PEG10 (Gene)
Timolol (Compound) causes Affect lability (Side Effect)
Timolol may cause a minor interaction that can limit clinical effects when taken with Magnesium oxide
Timolol may cause a minor interaction that can limit clinical effects when taken with Liothyronine
Timolol may cause a moderate interaction that could exacerbate diseases when taken with Iopodic acid
Timolol may cause a moderate interaction that could exacerbate diseases when taken with Gadodiamide