DDInter458 DDInter960
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus _Beauveria nivea_. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Cyclosporine {u} (Compound) downregulates {v} (Gene) ITGAE
ITGAE {u} (Gene) is downregulated by {v} (Compound) Iohexol
Cyclosporine {u} (Compound) causes {v} (Side Effect) Hypersensitivity
Hypersensitivity {u} (Side Effect) is caused by {v} (Compound) Iohexol
Cyclosporine {u} (Compound) downregulates {v} (Gene) ITGAE
ITGAE {u} (Gene) is downregulated by {v} (Compound) Iodixanol
Iodixanol {u} (Compound) resembles {v} (Compound) Iohexol
Cyclosporine {u} (Compound) causes {v} (Side Effect) Hypersensitivity
Hypersensitivity {u} (Side Effect) is caused by {v} (Compound) Labetalol
Labetalol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iohexol
Cyclosporine {u} (Compound) causes {v} (Side Effect) Dermatitis
Dermatitis {u} (Side Effect) is caused by {v} (Compound) Iodixanol
Iodixanol {u} (Compound) resembles {v} (Compound) Iohexol
Cyclosporine {u} (Compound) upregulates {v} (Gene) XBP1
XBP1 {u} (Gene) is upregulated by {v} (Compound) Iodixanol
Iodixanol {u} (Compound) resembles {v} (Compound) Iohexol
Cyclosporine {u} (Compound) causes {v} (Side Effect) Salivary gland enlargement
Salivary gland enlargement {u} (Side Effect) is caused by {v} (Compound) Clomipramine
Clomipramine {u} may lead to a major life threatening interaction when taken with {v} Iohexol
Cyclosporine {u} (Compound) downregulates {v} (Gene) ITGAE
ITGAE {u} (Gene) is downregulated by {v} (Compound) Methazolamide
Methazolamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iohexol
Cyclosporine {u} (Compound) upregulates {v} (Gene) XBP1
XBP1 {u} (Gene) regulates {v} (Gene) AGR2
AGR2 {u} (Gene) is upregulated by {v} (Compound) Iohexol
Cyclosporine {u} (Compound) downregulates {v} (Gene) ITGAE
ITGAE {u} (Gene) is downregulated by {v} (Compound) Sulfasalazine
Sulfasalazine {u} may lead to a major life threatening interaction when taken with {v} Iohexol
Cyclosporine (Compound) downregulates ITGAE (Gene) and ITGAE (Gene) is downregulated by Iohexol (Compound)
Cyclosporine (Compound) causes Hypersensitivity (Side Effect) and Hypersensitivity (Side Effect) is caused by Iohexol (Compound)
Cyclosporine (Compound) downregulates ITGAE (Gene) and ITGAE (Gene) is downregulated by Iodixanol (Compound) and Iodixanol (Compound) resembles Iohexol (Compound)
Cyclosporine (Compound) causes Hypersensitivity (Side Effect) and Hypersensitivity (Side Effect) is caused by Labetalol (Compound) and Labetalol may cause a moderate interaction that could exacerbate diseases when taken with Iohexol
Cyclosporine (Compound) causes Dermatitis (Side Effect) and Dermatitis (Side Effect) is caused by Iodixanol (Compound) and Iodixanol (Compound) resembles Iohexol (Compound)
Cyclosporine (Compound) upregulates XBP1 (Gene) and XBP1 (Gene) is upregulated by Iodixanol (Compound) and Iodixanol (Compound) resembles Iohexol (Compound)
Cyclosporine (Compound) causes Salivary gland enlargement (Side Effect) and Salivary gland enlargement (Side Effect) is caused by Clomipramine (Compound) and Clomipramine may lead to a major life threatening interaction when taken with Iohexol
Cyclosporine (Compound) downregulates ITGAE (Gene) and ITGAE (Gene) is downregulated by Methazolamide (Compound) and Methazolamide may cause a moderate interaction that could exacerbate diseases when taken with Iohexol
Cyclosporine (Compound) upregulates XBP1 (Gene) and XBP1 (Gene) regulates AGR2 (Gene) and AGR2 (Gene) is upregulated by Iohexol (Compound)
Cyclosporine (Compound) downregulates ITGAE (Gene) and ITGAE (Gene) is downregulated by Sulfasalazine (Compound) and Sulfasalazine may lead to a major life threatening interaction when taken with Iohexol