DDInter1013 DDInter1676
Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.
Siponimod, also known as _Mayzent_, by Novartis, is a new drug formulated for the management of Multiple Sclerosis (MS). It was approved by the FDA on March 26, 2019 and by Health Canada on February 20, 2020. This drug is considered a _sphingosine-1-phosphate (S1P) receptor modulator_ and is thought to play a role in suppressing the central nervous system inflammation that is associated with MS [FDA label]. Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system that is chronic and inflammatory, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of life. Symptoms may include but are not limited to fatigue, gait changes, bowel or bladder dysfunction, abnormal muscle twitching, vision disturbance, and depressing or mood swings. MS is one of the most common causes of neurological disability in young adults and is found to occur more frequently in women than in men.[A176474,L5792]
Labetalol {u} (Compound) resembles {v} (Compound) Fenoprofen
Labetalol {u} may lead to a major life threatening interaction when taken with {v} Salmeterol
Labetalol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Isoprenaline
Labetalol {u} (Compound) resembles {v} (Compound) Benazepril
Labetalol {u} (Compound) treats {v} (Disease) hypertension
Labetalol {u} (Compound) binds {v} (Gene) CYP2D6
Labetalol {u} (Compound) causes {v} (Side Effect) Lupus erythematosus
Labetalol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Liothyronine
Labetalol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magaldrate
Labetalol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cimetidine
Labetalol (Compound) resembles Fenoprofen (Compound)
Labetalol may lead to a major life threatening interaction when taken with Salmeterol
Labetalol may cause a moderate interaction that could exacerbate diseases when taken with Isoprenaline
Labetalol (Compound) resembles Benazepril (Compound)
Labetalol (Compound) treats hypertension (Disease)
Labetalol (Compound) binds CYP2D6 (Gene)
Labetalol (Compound) causes Lupus erythematosus (Side Effect)
Labetalol may cause a minor interaction that can limit clinical effects when taken with Liothyronine
Labetalol may cause a minor interaction that can limit clinical effects when taken with Magaldrate
Labetalol may cause a moderate interaction that could exacerbate diseases when taken with Cimetidine