DDInter1783 DDInter248
Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the bacterial 50S ribosomal subunit and may alter the cytoplasmic membrane causing intracellular components to leak from bacterial cells. The FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml. Other formulations of tetracycline continue to be used.
Bumetanide is a sulfamyl diuretic.
Tetracycline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Bumetanide
Tetracycline {u} (Compound) binds {v} (Gene) SLC22A11
SLC22A11 {u} (Gene) is bound by {v} (Compound) Bumetanide
Tetracycline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Furosemide {u} (Compound) resembles {v} (Compound) Bumetanide
Tetracycline {u} (Compound) binds {v} (Gene) SLC22A11
SLC22A11 {u} (Gene) is bound by {v} (Compound) Furosemide
Furosemide {u} (Compound) resembles {v} (Compound) Bumetanide
Tetracycline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metolazone
Metolazone {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Bumetanide
Tetracycline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Indapamide
Indapamide {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Bumetanide
Tetracycline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metolazone
Metolazone {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Bumetanide
Tetracycline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Indapamide
Indapamide {u} (Compound) binds {v} (Gene) CA12
CA12 {u} (Gene) is bound by {v} (Compound) Bumetanide
Tetracycline {u} (Compound) resembles {v} (Compound) Minocycline
Minocycline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Bumetanide
Tetracycline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metolazone
Metolazone {u} (Compound) binds {v} (Gene) CA12
CA12 {u} (Gene) is bound by {v} (Compound) Bumetanide
Tetracycline may cause a minor interaction that can limit clinical effects when taken with Indapamide and Indapamide (Compound) resembles Bumetanide (Compound)
Tetracycline (Compound) binds SLC22A11 (Gene) and SLC22A11 (Gene) is bound by Bumetanide (Compound)
Tetracycline may cause a minor interaction that can limit clinical effects when taken with Indapamide and Indapamide (Compound) resembles Furosemide (Compound) and Furosemide (Compound) resembles Bumetanide (Compound)
Tetracycline (Compound) binds SLC22A11 (Gene) and SLC22A11 (Gene) is bound by Furosemide (Compound) and Furosemide (Compound) resembles Bumetanide (Compound)
Tetracycline may cause a minor interaction that can limit clinical effects when taken with Metolazone and Metolazone (Compound) resembles Indapamide (Compound) and Indapamide (Compound) resembles Bumetanide (Compound)
Tetracycline may cause a minor interaction that can limit clinical effects when taken with Indapamide and Indapamide (Compound) treats hypertension (Disease) and hypertension (Disease) is treated by Bumetanide (Compound)
Tetracycline may cause a minor interaction that can limit clinical effects when taken with Metolazone and Metolazone (Compound) treats hypertension (Disease) and hypertension (Disease) is treated by Bumetanide (Compound)
Tetracycline may cause a minor interaction that can limit clinical effects when taken with Indapamide and Indapamide (Compound) binds CA12 (Gene) and CA12 (Gene) is bound by Bumetanide (Compound)
Tetracycline (Compound) resembles Minocycline (Compound) and Minocycline may cause a minor interaction that can limit clinical effects when taken with Indapamide and Indapamide (Compound) resembles Bumetanide (Compound)
Tetracycline may cause a minor interaction that can limit clinical effects when taken with Metolazone and Metolazone (Compound) binds CA12 (Gene) and CA12 (Gene) is bound by Bumetanide (Compound)