DDInter948 DDInter1152
Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Mephenytoin is used for the treatment of refractory partial epilepsy. Mephenytoin is a solid. This compound belongs to the phenylhydantoins. These are heterocyclic aromatic compounds containing an imiazolidinedione moiety substituted by a phenyl group. Mephenytoin is known to target sodium channel protein type 5 subunit alpha. Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2B6, Cytochrome P450 1A2, and Cytochrome P450 2D6 are known to metabolize mephenytoin. Mephenytoin is a hydantoin-derivative anticonvulsant used to control various partial seizures. Mephenytoin and oxazolidinedione derivatives are associated with higher incidences of blood dyscrasias compared to other anticonvulsants.
Mephenytoin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Lidocaine
Mephenytoin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Esomeprazole
Mephenytoin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cetirizine
Mephenytoin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Peginterferon beta-1a
Mephenytoin {u} may lead to a major life threatening interaction when taken with {v} Teriflunomide
Mephenytoin {u} may lead to a major life threatening interaction when taken with {v} Fluconazole
Mephenytoin may cause a minor interaction that can limit clinical effects when taken with Lidocaine
Mephenytoin may cause a minor interaction that can limit clinical effects when taken with Esomeprazole
Mephenytoin may cause a moderate interaction that could exacerbate diseases when taken with Cetirizine
Mephenytoin may cause a moderate interaction that could exacerbate diseases when taken with Peginterferon beta-1a
Mephenytoin may lead to a major life threatening interaction when taken with Teriflunomide
Mephenytoin may lead to a major life threatening interaction when taken with Fluconazole