DDInter1537 DDInter154
Propiomazine, an atypical antipsychotic agent, is used to treat both negative and positive symptoms of schizophrenia, acute mania with bipolar disorder, agitation, and psychotic symptoms in dementia. Future uses may include the treatment of obsessive-compulsive disorder and severe behavioral disorders in autism. Structurally and pharmacologically similar to clozapine, propiomazine binds to alpha(1), dopamine, histamine H1, muscarinic, and serotonin type 2 (5-HT2) receptors.
Azelastine is a phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position. It has a role as a H1-receptor antagonist, an anti-allergic agent, an anti-asthmatic drug, a bronchodilator agent, a platelet aggregation inhibitor and an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. It is a member of phthalazines, a tertiary amino compound and a member of monochlorobenzenes.
Propiomazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clemastine
Clemastine {u} (Compound) resembles {v} (Compound) Azelastine
Propiomazine {u} (Compound) binds {v} (Gene) HRH1
HRH1 {u} (Gene) is bound by {v} (Compound) Azelastine
Propiomazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clemastine
Clemastine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) Azelastine
Propiomazine {u} (Compound) binds {v} (Gene) HRH1
HRH1 {u} (Gene) is bound by {v} (Compound) Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) Azelastine
Propiomazine {u} (Compound) resembles {v} (Compound) Promazine
Promazine {u} (Compound) binds {v} (Gene) CYP2C9
CYP2C9 {u} (Gene) is bound by {v} (Compound) Azelastine
Propiomazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Promethazine
Promethazine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Azelastine
Propiomazine {u} (Compound) resembles {v} (Compound) Promazine
Promazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clemastine
Clemastine {u} (Compound) resembles {v} (Compound) Azelastine
Propiomazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clemastine
Clemastine {u} (Compound) resembles {v} (Compound) Buclizine
Buclizine {u} (Compound) resembles {v} (Compound) Azelastine
Propiomazine {u} (Compound) resembles {v} (Compound) Trifluoperazine
Trifluoperazine {u} (Compound) resembles {v} (Compound) Clozapine
Clozapine {u} (Compound) resembles {v} (Compound) Azelastine
Propiomazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Promethazine
Promethazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) Azelastine
Propiomazine may cause a moderate interaction that could exacerbate diseases when taken with Clemastine and Clemastine (Compound) resembles Azelastine (Compound)
Propiomazine (Compound) binds HRH1 (Gene) and HRH1 (Gene) is bound by Azelastine (Compound)
Propiomazine may cause a moderate interaction that could exacerbate diseases when taken with Clemastine and Clemastine may cause a moderate interaction that could exacerbate diseases when taken with Loxapine and Loxapine (Compound) resembles Azelastine (Compound)
Propiomazine (Compound) binds HRH1 (Gene) and HRH1 (Gene) is bound by Loxapine (Compound) and Loxapine (Compound) resembles Azelastine (Compound)
Propiomazine (Compound) resembles Promazine (Compound) and Promazine (Compound) binds CYP2C9 (Gene) and CYP2C9 (Gene) is bound by Azelastine (Compound)
Propiomazine may cause a moderate interaction that could exacerbate diseases when taken with Promethazine and Promethazine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Azelastine (Compound)
Propiomazine (Compound) resembles Promazine (Compound) and Promazine may cause a moderate interaction that could exacerbate diseases when taken with Clemastine and Clemastine (Compound) resembles Azelastine (Compound)
Propiomazine may cause a moderate interaction that could exacerbate diseases when taken with Clemastine and Clemastine (Compound) resembles Buclizine (Compound) and Buclizine (Compound) resembles Azelastine (Compound)
Propiomazine (Compound) resembles Trifluoperazine (Compound) and Trifluoperazine (Compound) resembles Clozapine (Compound) and Clozapine (Compound) resembles Azelastine (Compound)
Propiomazine may cause a moderate interaction that could exacerbate diseases when taken with Promethazine and Promethazine may cause a moderate interaction that could exacerbate diseases when taken with Loxapine and Loxapine (Compound) resembles Azelastine (Compound)