DDInter804 DDInter1763
Gallium nitrate is a nitrate salt of, a heavy metal that has been used as a diagnostic agent. Gallium nitrate is reported to possess antiresorptive and hypocalcemic effects on bone. GANITE, a product of gallium nitrate previously used to treat cancer-related hypercalcemia, was discontinued from marketing in the US for reasons other than safety or effectiveness. Apart from cancer-related hypercalcemia, gallium nitrate has been studied in arthritis, autoimmune disorders, and tumours.
Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). It was developed by Wyeth Pharmaceuticals under the trade name Torisel. Temsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007.
Gallium nitrate {u} may lead to a major life threatening interaction when taken with {v} Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Gallium nitrate {u} (Compound) binds {v} (Gene) TF
TF {u} (Gene) is upregulated by {v} (Compound) Temsirolimus
Gallium nitrate {u} (Compound) causes {v} (Side Effect) Hypersensitivity
Hypersensitivity {u} (Side Effect) is caused by {v} (Compound) Temsirolimus
Gallium nitrate {u} may lead to a major life threatening interaction when taken with {v} Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Everolimus
Everolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Gallium nitrate {u} (Compound) binds {v} (Gene) TF
TF {u} (Gene) is regulated by {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Temsirolimus
Gallium nitrate {u} (Compound) causes {v} (Side Effect) Hypersensitivity
Hypersensitivity {u} (Side Effect) is caused by {v} (Compound) Everolimus
Everolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Gallium nitrate {u} (Compound) binds {v} (Gene) RRM2
RRM2 {u} (Gene) regulates {v} (Gene) B4GAT1
B4GAT1 {u} (Gene) is downregulated by {v} (Compound) Temsirolimus
Gallium nitrate {u} (Compound) binds {v} (Gene) TF
TF {u} (Gene) is regulated by {v} (Gene) KIAA0355
KIAA0355 {u} (Gene) is upregulated by {v} (Compound) Temsirolimus
Gallium nitrate {u} (Compound) binds {v} (Gene) ATP6V1B2
ATP6V1B2 {u} (Gene) is regulated by {v} (Gene) POP4
POP4 {u} (Gene) is downregulated by {v} (Compound) Temsirolimus
Gallium nitrate {u} (Compound) binds {v} (Gene) IL1B
IL1B {u} (Gene) interacts with {v} (Gene) TBP
TBP {u} (Gene) is downregulated by {v} (Compound) Temsirolimus
Gallium nitrate may lead to a major life threatening interaction when taken with Sirolimus and Sirolimus (Compound) resembles Temsirolimus (Compound)
Gallium nitrate (Compound) binds TF (Gene) and TF (Gene) is upregulated by Temsirolimus (Compound)
Gallium nitrate (Compound) causes Hypersensitivity (Side Effect) and Hypersensitivity (Side Effect) is caused by Temsirolimus (Compound)
Gallium nitrate may lead to a major life threatening interaction when taken with Sirolimus and Sirolimus (Compound) resembles Everolimus (Compound) and Everolimus (Compound) resembles Temsirolimus (Compound)
Gallium nitrate (Compound) binds TF (Gene) and TF (Gene) is regulated by ABCB1 (Gene) and ABCB1 (Gene) is bound by Temsirolimus (Compound)
Gallium nitrate (Compound) causes Hypersensitivity (Side Effect) and Hypersensitivity (Side Effect) is caused by Everolimus (Compound) and Everolimus (Compound) resembles Temsirolimus (Compound)
Gallium nitrate (Compound) binds RRM2 (Gene) and RRM2 (Gene) regulates B4GAT1 (Gene) and B4GAT1 (Gene) is downregulated by Temsirolimus (Compound)
Gallium nitrate (Compound) binds TF (Gene) and TF (Gene) is regulated by KIAA0355 (Gene) and KIAA0355 (Gene) is upregulated by Temsirolimus (Compound)
Gallium nitrate (Compound) binds ATP6V1B2 (Gene) and ATP6V1B2 (Gene) is regulated by POP4 (Gene) and POP4 (Gene) is downregulated by Temsirolimus (Compound)
Gallium nitrate (Compound) binds IL1B (Gene) and IL1B (Gene) interacts with TBP (Gene) and TBP (Gene) is downregulated by Temsirolimus (Compound)