DDInter1470 DDInter1016
A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403)
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose]. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. [sucrose]). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in patients with cirrhosis.[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.
Pimozide {u} (Compound) resembles {v} (Compound) Fexofenadine
Pimozide {u} (Compound) resembles {v} (Compound) Ezetimibe
Pimozide {u} may lead to a major life threatening interaction when taken with {v} Astemizole
Pimozide {u} (Compound) binds {v} (Gene) CALM3
Pimozide {u} (Compound) upregulates {v} (Gene) GNPDA1
Pimozide {u} (Compound) palliates {v} (Disease) Gilles de la Tourette syndrome
Pimozide {u} (Compound) downregulates {v} (Gene) TMEM109
Pimozide {u} (Compound) causes {v} (Side Effect) Hypertension
Pimozide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metronidazole
Pimozide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Hyoscyamine
Pimozide (Compound) resembles Fexofenadine (Compound)
Pimozide (Compound) resembles Ezetimibe (Compound)
Pimozide may lead to a major life threatening interaction when taken with Astemizole
Pimozide (Compound) binds CALM3 (Gene)
Pimozide (Compound) upregulates GNPDA1 (Gene)
Pimozide (Compound) palliates Gilles de la Tourette syndrome (Disease)
Pimozide (Compound) downregulates TMEM109 (Gene)
Pimozide (Compound) causes Hypertension (Side Effect)
Pimozide may cause a minor interaction that can limit clinical effects when taken with Metronidazole
Pimozide may cause a moderate interaction that could exacerbate diseases when taken with Hyoscyamine