DDInter350 DDInter285
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue.
Chlorambucil {u} (Compound) treats {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Capecitabine
Chlorambucil {u} (Compound) causes {v} (Side Effect) Dyspepsia
Dyspepsia {u} (Side Effect) is caused by {v} (Compound) Capecitabine
Chlorambucil {u} (Compound) resembles {v} (Compound) Melphalan
Melphalan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Capecitabine
Chlorambucil {u} (Compound) treats {v} (Disease) breast cancer
breast cancer {u} (Disease) resembles {v} (Disease) colon cancer
colon cancer {u} (Disease) is treated by {v} (Compound) Capecitabine
Chlorambucil {u} (Compound) causes {v} (Side Effect) Dyspepsia
Dyspepsia {u} (Side Effect) is caused by {v} (Compound) Gemifloxacin
Gemifloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Capecitabine
Chlorambucil {u} (Compound) causes {v} (Side Effect) Neoplasm
Neoplasm {u} (Side Effect) is caused by {v} (Compound) Moxifloxacin
Moxifloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Capecitabine
Chlorambucil {u} (Compound) treats {v} (Disease) ovarian cancer
ovarian cancer {u} (Disease) is treated by {v} (Compound) Melphalan
Melphalan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Capecitabine
Chlorambucil {u} (Compound) resembles {v} (Compound) Melphalan
Melphalan {u} (Compound) treats {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Capecitabine
Chlorambucil {u} (Compound) treats {v} (Disease) breast cancer
breast cancer {u} (Disease) is associated with {v} (Gene) and {u} (Disease) upregulates {v} (Gene) TYMS
TYMS {u} (Gene) is bound by {v} (Compound) Capecitabine
Chlorambucil {u} (Compound) causes {v} (Side Effect) Overdose
Overdose {u} (Side Effect) is caused by {v} (Compound) Leflunomide
Leflunomide {u} may lead to a major life threatening interaction when taken with {v} Capecitabine
Chlorambucil (Compound) treats breast cancer (Disease) and breast cancer (Disease) is treated by Capecitabine (Compound)
Chlorambucil (Compound) causes Dyspepsia (Side Effect) and Dyspepsia (Side Effect) is caused by Capecitabine (Compound)
Chlorambucil (Compound) resembles Melphalan (Compound) and Melphalan may cause a moderate interaction that could exacerbate diseases when taken with Capecitabine
Chlorambucil (Compound) treats breast cancer (Disease) and breast cancer (Disease) resembles colon cancer (Disease) and colon cancer (Disease) is treated by Capecitabine (Compound)
Chlorambucil (Compound) causes Dyspepsia (Side Effect) and Dyspepsia (Side Effect) is caused by Gemifloxacin (Compound) and Gemifloxacin may cause a minor interaction that can limit clinical effects when taken with Capecitabine
Chlorambucil (Compound) causes Neoplasm (Side Effect) and Neoplasm (Side Effect) is caused by Moxifloxacin (Compound) and Moxifloxacin may cause a minor interaction that can limit clinical effects when taken with Capecitabine
Chlorambucil (Compound) treats ovarian cancer (Disease) and ovarian cancer (Disease) is treated by Melphalan (Compound) and Melphalan may cause a moderate interaction that could exacerbate diseases when taken with Capecitabine
Chlorambucil (Compound) resembles Melphalan (Compound) and Melphalan (Compound) treats breast cancer (Disease) and breast cancer (Disease) is treated by Capecitabine (Compound)
Chlorambucil (Compound) treats breast cancer (Disease) and breast cancer (Disease) is associated with TYMS (Gene) and breast cancer (Disease) upregulates TYMS (Gene) and TYMS (Gene) is bound by Capecitabine (Compound)
Chlorambucil (Compound) causes Overdose (Side Effect) and Overdose (Side Effect) is caused by Leflunomide (Compound) and Leflunomide may lead to a major life threatening interaction when taken with Capecitabine