DDInter1927 DDInter1016
Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, [desvenlafaxine], works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood regulation. Venlafaxine is officially approved to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and panic disorder in adults. The immediate formulation of the drug, marketed as Effexor, was first approved by the FDA in 1993 and the extended-release formulation, Effexor XR, was later introduced in 1997. Venlafaxine has been used as a first-line treatment for MDD, GAD, social anxiety disorder, and panic disorder in Canada for many years. It was also considered a second-line treatment for obsessive-compulsive disorder (OCD).[A177226,A177235] Venl
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose]. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. [sucrose]). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in patients with cirrhosis.[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.
Venlafaxine {u} (Compound) resembles {v} (Compound) Tramadol
Venlafaxine {u} (Compound) resembles {v} (Compound) Desvenlafaxine
Venlafaxine {u} (Compound) binds {v} (Gene) NPY1R
Venlafaxine {u} (Compound) palliates {v} (Disease) panic disorder
Venlafaxine {u} (Compound) is included by {v} (Pharmacologic Class) Norepinephrine Uptake Inhibitors
Venlafaxine {u} (Compound) causes {v} (Side Effect) Yawning
Venlafaxine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metronidazole
Venlafaxine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lenvatinib
Venlafaxine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eptifibatide
Venlafaxine {u} may lead to a major life threatening interaction when taken with {v} Procarbazine
Venlafaxine (Compound) resembles Tramadol (Compound)
Venlafaxine (Compound) resembles Desvenlafaxine (Compound)
Venlafaxine (Compound) binds NPY1R (Gene)
Venlafaxine (Compound) palliates panic disorder (Disease)
Venlafaxine (Compound) is included by Norepinephrine Uptake Inhibitors (Pharmacologic Class)
Venlafaxine (Compound) causes Yawning (Side Effect)
Venlafaxine may cause a minor interaction that can limit clinical effects when taken with Metronidazole
Venlafaxine may cause a moderate interaction that could exacerbate diseases when taken with Lenvatinib
Venlafaxine may cause a moderate interaction that could exacerbate diseases when taken with Eptifibatide
Venlafaxine may lead to a major life threatening interaction when taken with Procarbazine