DDInter947 DDInter458
Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interferon beta.
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus _Beauveria nivea_. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
Interferon beta-1a {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pasireotide
Pasireotide {u} (Compound) causes {v} (Side Effect) Abdominal pain
Abdominal pain {u} (Side Effect) is caused by {v} (Compound) Cyclosporine
Interferon beta-1a {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Isoniazid
Isoniazid {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Cyclosporine
Interferon beta-1a {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Bromfenac
Bromfenac {u} (Compound) downregulates {v} (Gene) IFRD2
IFRD2 {u} (Gene) is downregulated by {v} (Compound) Cyclosporine
Interferon beta-1a {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tizanidine
Tizanidine {u} (Compound) downregulates {v} (Gene) MTHFD2
MTHFD2 {u} (Gene) is upregulated by {v} (Compound) Cyclosporine
Interferon beta-1a {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indomethacin
Indomethacin {u} (Compound) palliates {v} (Disease) rheumatoid arthritis
rheumatoid arthritis {u} (Disease) is treated by {v} (Compound) Cyclosporine
Interferon beta-1a {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tioguanine
Tioguanine {u} (Compound) binds {v} (Gene) HPRT1
HPRT1 {u} (Gene) is downregulated by {v} (Compound) Cyclosporine
Interferon beta-1a {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acitretin
Acitretin {u} (Compound) treats {v} (Disease) psoriasis
psoriasis {u} (Disease) is treated by {v} (Compound) Cyclosporine
Interferon beta-1a {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Zileuton
Zileuton {u} (Compound) downregulates {v} (Gene) FKBP4
FKBP4 {u} (Gene) is bound by {v} (Compound) Cyclosporine
Interferon beta-1a {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Bortezomib
Bortezomib {u} (Compound) upregulates {v} (Gene) IFRD1
IFRD1 {u} (Gene) is upregulated by {v} (Compound) Cyclosporine
Interferon beta-1a {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ivacaftor
Ivacaftor {u} (Compound) is included by {v} (Pharmacologic Class) P-Glycoprotein Inhibitors
P-Glycoprotein Inhibitors {u} (Pharmacologic Class) includes {v} (Compound) Cyclosporine
Interferon beta-1a may cause a moderate interaction that could exacerbate diseases when taken with Pasireotide and Pasireotide (Compound) causes Abdominal pain (Side Effect) and Abdominal pain (Side Effect) is caused by Cyclosporine (Compound)
Interferon beta-1a may cause a moderate interaction that could exacerbate diseases when taken with Isoniazid and Isoniazid (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Cyclosporine (Compound)
Interferon beta-1a may cause a moderate interaction that could exacerbate diseases when taken with Bromfenac and Bromfenac (Compound) downregulates IFRD2 (Gene) and IFRD2 (Gene) is downregulated by Cyclosporine (Compound)
Interferon beta-1a may cause a moderate interaction that could exacerbate diseases when taken with Tizanidine and Tizanidine (Compound) downregulates MTHFD2 (Gene) and MTHFD2 (Gene) is upregulated by Cyclosporine (Compound)
Interferon beta-1a may cause a moderate interaction that could exacerbate diseases when taken with Indomethacin and Indomethacin (Compound) palliates rheumatoid arthritis (Disease) and rheumatoid arthritis (Disease) is treated by Cyclosporine (Compound)
Interferon beta-1a may cause a moderate interaction that could exacerbate diseases when taken with Tioguanine and Tioguanine (Compound) binds HPRT1 (Gene) and HPRT1 (Gene) is downregulated by Cyclosporine (Compound)
Interferon beta-1a may cause a moderate interaction that could exacerbate diseases when taken with Acitretin and Acitretin (Compound) treats psoriasis (Disease) and psoriasis (Disease) is treated by Cyclosporine (Compound)
Interferon beta-1a may cause a moderate interaction that could exacerbate diseases when taken with Zileuton and Zileuton (Compound) downregulates FKBP4 (Gene) and FKBP4 (Gene) is bound by Cyclosporine (Compound)
Interferon beta-1a may cause a moderate interaction that could exacerbate diseases when taken with Bortezomib and Bortezomib (Compound) upregulates IFRD1 (Gene) and IFRD1 (Gene) is upregulated by Cyclosporine (Compound)
Interferon beta-1a may cause a moderate interaction that could exacerbate diseases when taken with Ivacaftor and Ivacaftor (Compound) is included by P-Glycoprotein Inhibitors (Pharmacologic Class) and P-Glycoprotein Inhibitors (Pharmacologic Class) includes Cyclosporine (Compound)