DDInter1276 DDInter1082
Nelfinavir is a potent HIV-1 protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children. Nelfinavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.
Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM). It is sold by Sanofi-Aventis under the brand name Adlyxin in the US and Lyxumia in the EU. Adlyxin recieved FDA approval July 28, 2016.
Nelfinavir {u} (Compound) resembles {v} (Compound) Mitiglinide
Nelfinavir {u} (Compound) resembles {v} (Compound) Indinavir
Nelfinavir {u} (Compound) treats {v} (Disease) acquired immunodeficiency syndrome
Nelfinavir {u} (Compound) binds {v} (Gene) CYP3A7-CYP3A51P
Nelfinavir {u} (Compound) upregulates {v} (Gene) AARS
Nelfinavir {u} (Compound) downregulates {v} (Gene) RPIA
Nelfinavir {u} (Compound) causes {v} (Side Effect) Injury
Nelfinavir {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ranitidine
Nelfinavir {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Repaglinide
Nelfinavir {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Insulin lispro
Nelfinavir (Compound) resembles Mitiglinide (Compound)
Nelfinavir (Compound) resembles Indinavir (Compound)
Nelfinavir (Compound) treats acquired immunodeficiency syndrome (Disease)
Nelfinavir (Compound) binds CYP3A7-CYP3A51P (Gene)
Nelfinavir (Compound) upregulates AARS (Gene)
Nelfinavir (Compound) downregulates RPIA (Gene)
Nelfinavir (Compound) causes Injury (Side Effect)
Nelfinavir may cause a minor interaction that can limit clinical effects when taken with Ranitidine
Nelfinavir may cause a moderate interaction that could exacerbate diseases when taken with Repaglinide
Nelfinavir may cause a moderate interaction that could exacerbate diseases when taken with Insulin lispro