DDInter698 DDInter1004
Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid]. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and [risedronic acid]. Etidronic acid was granted FDA approval on 1 September 1977.
Kanamycin (also known as kanamycin A) is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections. Kanamycin is isolated from the bacterium Streptomyces kanamyceticus and its most commonly used form is kanamycin sulfate.
Etidronic acid {u} (Compound) downregulates {v} (Gene) PUF60
PUF60 {u} (Gene) is downregulated by {v} (Compound) Kanamycin
Etidronic acid {u} (Compound) causes {v} (Side Effect) Paraesthesia
Paraesthesia {u} (Side Effect) is caused by {v} (Compound) Kanamycin
Etidronic acid {u} (Compound) resembles {v} (Compound) Alendronic acid
Alendronic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Kanamycin
Etidronic acid {u} (Compound) downregulates {v} (Gene) PUF60
PUF60 {u} (Gene) regulates {v} (Gene) DLD
DLD {u} (Gene) is downregulated by {v} (Compound) Kanamycin
Etidronic acid {u} (Compound) causes {v} (Side Effect) Paraesthesia
Paraesthesia {u} (Side Effect) is caused by {v} (Compound) Tobramycin
Tobramycin {u} (Compound) resembles {v} (Compound) Kanamycin
Etidronic acid {u} (Compound) resembles {v} (Compound) Alendronic acid
Alendronic acid {u} (Compound) causes {v} (Side Effect) Rash
Rash {u} (Side Effect) is caused by {v} (Compound) Kanamycin
Etidronic acid {u} (Compound) resembles {v} (Compound) Risedronic acid
Risedronic acid {u} (Compound) binds {v} (Gene) PTGS2
PTGS2 {u} (Gene) is upregulated by {v} (Compound) Kanamycin
Etidronic acid {u} (Compound) resembles {v} (Compound) Clodronate
Clodronate {u} (Compound) resembles {v} (Compound) Zoledronic acid
Zoledronic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Kanamycin
Etidronic acid {u} (Compound) downregulates {v} (Gene) PUF60
PUF60 {u} (Gene) is downregulated by {v} (Compound) Diclofenac
Diclofenac {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Kanamycin
Etidronic acid {u} (Compound) causes {v} (Side Effect) Paraesthesia
Paraesthesia {u} (Side Effect) is caused by {v} (Compound) Amikacin
Amikacin {u} (Compound) resembles {v} (Compound) Kanamycin
Etidronic acid (Compound) downregulates PUF60 (Gene) and PUF60 (Gene) is downregulated by Kanamycin (Compound)
Etidronic acid (Compound) causes Paraesthesia (Side Effect) and Paraesthesia (Side Effect) is caused by Kanamycin (Compound)
Etidronic acid (Compound) resembles Alendronic acid (Compound) and Alendronic acid may cause a moderate interaction that could exacerbate diseases when taken with Kanamycin
Etidronic acid (Compound) downregulates PUF60 (Gene) and PUF60 (Gene) regulates DLD (Gene) and DLD (Gene) is downregulated by Kanamycin (Compound)
Etidronic acid (Compound) causes Paraesthesia (Side Effect) and Paraesthesia (Side Effect) is caused by Tobramycin (Compound) and Tobramycin (Compound) resembles Kanamycin (Compound)
Etidronic acid (Compound) resembles Alendronic acid (Compound) and Alendronic acid (Compound) causes Rash (Side Effect) and Rash (Side Effect) is caused by Kanamycin (Compound)
Etidronic acid (Compound) resembles Risedronic acid (Compound) and Risedronic acid (Compound) binds PTGS2 (Gene) and PTGS2 (Gene) is upregulated by Kanamycin (Compound)
Etidronic acid (Compound) resembles Clodronate (Compound) and Clodronate (Compound) resembles Zoledronic acid (Compound) and Zoledronic acid may cause a moderate interaction that could exacerbate diseases when taken with Kanamycin
Etidronic acid (Compound) downregulates PUF60 (Gene) and PUF60 (Gene) is downregulated by Diclofenac (Compound) and Diclofenac may cause a moderate interaction that could exacerbate diseases when taken with Kanamycin
Etidronic acid (Compound) causes Paraesthesia (Side Effect) and Paraesthesia (Side Effect) is caused by Amikacin (Compound) and Amikacin (Compound) resembles Kanamycin (Compound)