DDInter458 DDInter1199
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus _Beauveria nivea_. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
A quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
Cyclosporine {u} (Compound) causes {v} (Side Effect) Anxiety
Anxiety {u} (Side Effect) is caused by {v} (Compound) Metolazone
Cyclosporine {u} (Compound) causes {v} (Side Effect) Anxiety
Anxiety {u} (Side Effect) is caused by {v} (Compound) Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Metolazone
Cyclosporine {u} (Compound) causes {v} (Side Effect) Hypomagnesaemia
Hypomagnesaemia {u} (Side Effect) is caused by {v} (Compound) Chlorthalidone
Chlorthalidone {u} (Compound) resembles {v} (Compound) Metolazone
Cyclosporine {u} (Compound) causes {v} (Side Effect) Abdominal distension
Abdominal distension {u} (Side Effect) is caused by {v} (Compound) Atropine
Atropine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metolazone
Cyclosporine {u} (Compound) causes {v} (Side Effect) Neuropathy
Neuropathy {u} (Side Effect) is caused by {v} (Compound) Prednisolone
Prednisolone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Metolazone
Cyclosporine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Metolazone
Cyclosporine {u} (Compound) causes {v} (Side Effect) Abdominal discomfort
Abdominal discomfort {u} (Side Effect) is caused by {v} (Compound) Trospium
Trospium {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metolazone
Cyclosporine {u} (Compound) causes {v} (Side Effect) Hepatitis
Hepatitis {u} (Side Effect) is caused by {v} (Compound) Acarbose
Acarbose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Metolazone
Cyclosporine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Doxycycline
Doxycycline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metolazone
Cyclosporine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Tetracycline
Tetracycline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metolazone
Cyclosporine (Compound) causes Anxiety (Side Effect) and Anxiety (Side Effect) is caused by Metolazone (Compound)
Cyclosporine (Compound) causes Anxiety (Side Effect) and Anxiety (Side Effect) is caused by Indapamide (Compound) and Indapamide (Compound) resembles Metolazone (Compound)
Cyclosporine (Compound) causes Hypomagnesaemia (Side Effect) and Hypomagnesaemia (Side Effect) is caused by Chlorthalidone (Compound) and Chlorthalidone (Compound) resembles Metolazone (Compound)
Cyclosporine (Compound) causes Abdominal distension (Side Effect) and Abdominal distension (Side Effect) is caused by Atropine (Compound) and Atropine may cause a minor interaction that can limit clinical effects when taken with Metolazone
Cyclosporine (Compound) causes Neuropathy (Side Effect) and Neuropathy (Side Effect) is caused by Prednisolone (Compound) and Prednisolone may cause a moderate interaction that could exacerbate diseases when taken with Metolazone
Cyclosporine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Indapamide (Compound) and Indapamide (Compound) resembles Metolazone (Compound)
Cyclosporine (Compound) causes Abdominal discomfort (Side Effect) and Abdominal discomfort (Side Effect) is caused by Trospium (Compound) and Trospium may cause a minor interaction that can limit clinical effects when taken with Metolazone
Cyclosporine (Compound) causes Hepatitis (Side Effect) and Hepatitis (Side Effect) is caused by Acarbose (Compound) and Acarbose may cause a moderate interaction that could exacerbate diseases when taken with Metolazone
Cyclosporine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Doxycycline (Compound) and Doxycycline may cause a minor interaction that can limit clinical effects when taken with Metolazone
Cyclosporine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Tetracycline (Compound) and Tetracycline may cause a minor interaction that can limit clinical effects when taken with Metolazone