DDInter1650 DDInter1376
Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. It is commonly known as quinalbarbitone in the United Kingdom.
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26, 2020.[L12573,L12582] The US approval was followed by the approval in Canada on October 2, 2020. In November 2021, ozanimod was also approved by the European Commission for the treatment of adults with relapsing remitting multiple sclerosis.[L39377,L39382] MS is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Inflammatory bowel disease also a chronic inflammatory condition and can cause persistent abdominal pain, diarrhea, bloody stools, and vomiting. In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard in MS therapy. Studies involving patients with inflammatory bowel disease have also shown promising results.[A189318,A189342]
Secobarbital {u} (Compound) resembles {v} (Compound) Amobarbital
Secobarbital {u} (Compound) resembles {v} (Compound) Thiopental
Secobarbital {u} (Compound) binds {v} (Gene) GRIK2
Secobarbital {u} (Compound) causes {v} (Side Effect) Hyperkinesia
Secobarbital {u} may cause a minor interaction that can limit clinical effects when taken with {v} Lidocaine
Secobarbital {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cimetidine
Secobarbital {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Irinotecan
Secobarbital {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Theophylline
Secobarbital {u} may lead to a major life threatening interaction when taken with {v} Morphine
Secobarbital {u} may lead to a major life threatening interaction when taken with {v} Hemin
Secobarbital (Compound) resembles Amobarbital (Compound)
Secobarbital (Compound) resembles Thiopental (Compound)
Secobarbital (Compound) binds GRIK2 (Gene)
Secobarbital (Compound) causes Hyperkinesia (Side Effect)
Secobarbital may cause a minor interaction that can limit clinical effects when taken with Lidocaine
Secobarbital may cause a minor interaction that can limit clinical effects when taken with Cimetidine
Secobarbital may cause a moderate interaction that could exacerbate diseases when taken with Irinotecan
Secobarbital may cause a moderate interaction that could exacerbate diseases when taken with Theophylline
Secobarbital may lead to a major life threatening interaction when taken with Morphine
Secobarbital may lead to a major life threatening interaction when taken with Hemin