DDInter1867 DDInter1744
A phenothiazine used as an antipsychotic agent and as an antiemetic.
Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.[L7799,L7802] Tamoxifen may no longer be the preferred treatment for these types of cancers as patients generally have better survival, side effect profiles, and compliance with [anastrozole]. Tamoxifen was granted FDA approval on 30 December 1977.
Triflupromazine {u} (Compound) resembles {v} (Compound) Dimetacrine
Dimetacrine {u} (Compound) resembles {v} (Compound) Tamoxifen
Triflupromazine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Tamoxifen
Triflupromazine {u} (Compound) upregulates {v} (Gene) EBP
EBP {u} (Gene) is bound by {v} (Compound) Tamoxifen
Triflupromazine {u} (Compound) upregulates {v} (Gene) GRN
GRN {u} (Gene) is upregulated by {v} (Compound) Tamoxifen
Triflupromazine {u} (Compound) downregulates {v} (Gene) CYCS
CYCS {u} (Gene) is downregulated by {v} (Compound) Tamoxifen
Triflupromazine {u} (Compound) resembles {v} (Compound) Chlorpromazine
Chlorpromazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tamoxifen
Triflupromazine {u} (Compound) resembles {v} (Compound) Clomipramine
Clomipramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tamoxifen
Triflupromazine {u} (Compound) resembles {v} (Compound) Thioridazine
Thioridazine {u} may lead to a major life threatening interaction when taken with {v} Tamoxifen
Triflupromazine {u} (Compound) upregulates {v} (Gene) DHCR7
DHCR7 {u} (Gene) is bound by {v} (Compound) and {u} (Gene) is upregulated by {v} (Compound) Tamoxifen
Triflupromazine {u} (Compound) resembles {v} (Compound) Promazine
Promazine {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tamoxifen
Triflupromazine (Compound) resembles Dimetacrine (Compound) and Dimetacrine (Compound) resembles Tamoxifen (Compound)
Triflupromazine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Tamoxifen (Compound)
Triflupromazine (Compound) upregulates EBP (Gene) and EBP (Gene) is bound by Tamoxifen (Compound)
Triflupromazine (Compound) upregulates GRN (Gene) and GRN (Gene) is upregulated by Tamoxifen (Compound)
Triflupromazine (Compound) downregulates CYCS (Gene) and CYCS (Gene) is downregulated by Tamoxifen (Compound)
Triflupromazine (Compound) resembles Chlorpromazine (Compound) and Chlorpromazine may cause a moderate interaction that could exacerbate diseases when taken with Tamoxifen
Triflupromazine (Compound) resembles Clomipramine (Compound) and Clomipramine may cause a moderate interaction that could exacerbate diseases when taken with Tamoxifen
Triflupromazine (Compound) resembles Thioridazine (Compound) and Thioridazine may lead to a major life threatening interaction when taken with Tamoxifen
Triflupromazine (Compound) upregulates DHCR7 (Gene) and DHCR7 (Gene) is bound by Tamoxifen (Compound) and DHCR7 (Gene) is upregulated by Tamoxifen (Compound)
Triflupromazine (Compound) resembles Promazine (Compound) and Promazine (Compound) resembles Tamoxifen (Compound) and Promazine may cause a moderate interaction that could exacerbate diseases when taken with Tamoxifen