DDInter569 DDInter1180
Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269, F3352]. As histamine receptors exist both peripherally and in the central nervous system, diphenhydramine has been shown to cause sedation due to its competitive antagonism of histamine H1 receptors within the central nervous system [L5263, L5266, L5269, F3379, A174541]. While its use in allergy therapy can sometimes fall out of favor due to its sedative effect, diphenhydramine has been repurposed
Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Diphenhydramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clofedanol
Diphenhydramine {u} (Compound) resembles {v} (Compound) Toremifene
Diphenhydramine {u} (Compound) resembles {v} (Compound) Tropicamide
Diphenhydramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dexbrompheniramine
Diphenhydramine {u} may lead to a major life threatening interaction when taken with {v} Tamoxifen
Diphenhydramine {u} (Compound) treats {v} (Disease) atopic dermatitis
Diphenhydramine {u} (Compound) binds {v} (Gene) CYP2B6
Diphenhydramine {u} (Compound) palliates {v} (Disease) schizophrenia
Diphenhydramine {u} (Compound) is included by {v} (Pharmacologic Class) Histamine H1 Receptor Antagonists
Diphenhydramine {u} (Compound) causes {v} (Side Effect) Dizziness
Diphenhydramine may cause a moderate interaction that could exacerbate diseases when taken with Clofedanol
Diphenhydramine (Compound) resembles Toremifene (Compound)
Diphenhydramine (Compound) resembles Tropicamide (Compound)
Diphenhydramine may cause a moderate interaction that could exacerbate diseases when taken with Dexbrompheniramine
Diphenhydramine may lead to a major life threatening interaction when taken with Tamoxifen
Diphenhydramine (Compound) treats atopic dermatitis (Disease)
Diphenhydramine (Compound) binds CYP2B6 (Gene)
Diphenhydramine (Compound) palliates schizophrenia (Disease)
Diphenhydramine (Compound) is included by Histamine H1 Receptor Antagonists (Pharmacologic Class)
Diphenhydramine (Compound) causes Dizziness (Side Effect)