DDInter534 DDInter1652
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome. (From Martindale, The Extra Pharmacopoeia, 30th ed, p589) Given diazepam's storied history as a commonly used and effective medication for a variety of indications, contemporary advancements in the formulation and administration of the agent include the development and US FDA approval of an auto-injectable formulation for the rapid treatment of uncontrolled seizures in 2015-2016. Combining diazepam, a proven effective therapy for acute repetitive seizures
Secukinumab is a fully human monoclonal IgG1/κ antibody against interleukin-17A (IL-17A), a proinflammatory cytokine implicated in various chronic immune-mediated inflammatory disorders, such as plaque psoriasis. By blocking the actions of IL-17A, secukinumab works to inhibit the pro-inflammatory pathways that drive immune-mediated inflammatory disorders. Following its first global approval in Japan in December 2014, secukinumab was approved by the European Commission on January 15, 2015, and by the FDA a few days after (January 21, 2015). It is currently approved to treat a number of chronic inflammatory conditions, such as plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, and hidradenitis suppurativa.[L39600,L42280,L48771]
Diazepam {u} (Compound) resembles {v} (Compound) Quazepam
Diazepam {u} (Compound) resembles {v} (Compound) Oxazepam
Diazepam {u} (Compound) treats {v} (Disease) epilepsy syndrome
Diazepam {u} (Compound) binds {v} (Gene) GABRB1
Diazepam {u} (Compound) palliates {v} (Disease) panic disorder
Diazepam {u} (Compound) is included by {v} (Pharmacologic Class) Benzodiazepines
Diazepam {u} (Compound) causes {v} (Side Effect) Thirst
Diazepam (Compound) resembles Quazepam (Compound)
Diazepam (Compound) resembles Oxazepam (Compound)
Diazepam (Compound) treats epilepsy syndrome (Disease)
Diazepam (Compound) binds GABRB1 (Gene)
Diazepam (Compound) palliates panic disorder (Disease)
Diazepam (Compound) is included by Benzodiazepines (Pharmacologic Class)
Diazepam (Compound) causes Thirst (Side Effect)