DDInter813 DDInter1016
Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. It is available in oral formulations. Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are essential for bacterial growth.
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose]. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. [sucrose]). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in patients with cirrhosis.[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.
Gemifloxacin {u} (Compound) resembles {v} (Compound) Lomefloxacin
Gemifloxacin {u} (Compound) resembles {v} (Compound) Levofloxacin
Gemifloxacin {u} (Compound) is included by {v} (Pharmacologic Class) Quinolones
Gemifloxacin {u} (Compound) causes {v} (Side Effect) Tendon rupture
Gemifloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Topotecan
Gemifloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Procarbazine
Gemifloxacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pazopanib
Gemifloxacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Terfenadine
Gemifloxacin {u} may lead to a major life threatening interaction when taken with {v} Nilotinib
Gemifloxacin {u} may lead to a major life threatening interaction when taken with {v} Triamcinolone
Gemifloxacin (Compound) resembles Lomefloxacin (Compound)
Gemifloxacin (Compound) resembles Levofloxacin (Compound)
Gemifloxacin (Compound) is included by Quinolones (Pharmacologic Class)
Gemifloxacin (Compound) causes Tendon rupture (Side Effect)
Gemifloxacin may cause a minor interaction that can limit clinical effects when taken with Topotecan
Gemifloxacin may cause a minor interaction that can limit clinical effects when taken with Procarbazine
Gemifloxacin may cause a moderate interaction that could exacerbate diseases when taken with Pazopanib
Gemifloxacin may cause a moderate interaction that could exacerbate diseases when taken with Terfenadine
Gemifloxacin may lead to a major life threatening interaction when taken with Nilotinib
Gemifloxacin may lead to a major life threatening interaction when taken with Triamcinolone