DDInter1873 DDInter534
Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome. (From Martindale, The Extra Pharmacopoeia, 30th ed, p589) Given diazepam's storied history as a commonly used and effective medication for a variety of indications, contemporary advancements in the formulation and administration of the agent include the development and US FDA approval of an auto-injectable formulation for the rapid treatment of uncontrolled seizures in 2015-2016 . Combining diazepam, a proven effective therapy for acute repetitive seizures, with an auto-injector designed for subcutaneous administration that is quickly and easily administered offers the potential for complete, consistent drug absorption and rapid onset of effect . This current development is subsequently an important addition to the rescue therapy tool chest for patients with epilepsy .
Trimethobenzamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Quazepam
Quazepam {u} (Compound) resembles {v} (Compound) Diazepam
Trimethobenzamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxazepam
Oxazepam {u} (Compound) resembles {v} (Compound) Diazepam
Trimethobenzamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lorazepam
Lorazepam {u} (Compound) resembles {v} (Compound) Diazepam
Trimethobenzamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Alprazolam
Alprazolam {u} (Compound) resembles {v} (Compound) Diazepam
Trimethobenzamide {u} (Compound) causes {v} (Side Effect) Drowsiness
Drowsiness {u} (Side Effect) is caused by {v} (Compound) Diazepam
Trimethobenzamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Quazepam
Quazepam {u} (Compound) resembles {v} (Compound) Flunitrazepam
Flunitrazepam {u} (Compound) resembles {v} (Compound) Diazepam
Trimethobenzamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxazepam
Oxazepam {u} (Compound) resembles {v} (Compound) Bromazepam
Bromazepam {u} (Compound) resembles {v} (Compound) Diazepam
Trimethobenzamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clomipramine
Clomipramine {u} (Compound) resembles {v} (Compound) Adinazolam
Adinazolam {u} (Compound) resembles {v} (Compound) Diazepam
Trimethobenzamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lorazepam
Lorazepam {u} (Compound) resembles {v} (Compound) Quazepam
Quazepam {u} (Compound) resembles {v} (Compound) Diazepam
Trimethobenzamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Alprazolam
Alprazolam {u} (Compound) resembles {v} (Compound) Quazepam
Quazepam {u} (Compound) resembles {v} (Compound) Diazepam
Trimethobenzamide may cause a moderate interaction that could exacerbate diseases when taken with Quazepam and Quazepam (Compound) resembles Diazepam (Compound)
Trimethobenzamide may cause a moderate interaction that could exacerbate diseases when taken with Oxazepam and Oxazepam (Compound) resembles Diazepam (Compound)
Trimethobenzamide may cause a moderate interaction that could exacerbate diseases when taken with Lorazepam and Lorazepam (Compound) resembles Diazepam (Compound)
Trimethobenzamide may cause a moderate interaction that could exacerbate diseases when taken with Alprazolam and Alprazolam (Compound) resembles Diazepam (Compound)
Trimethobenzamide (Compound) causes Drowsiness (Side Effect) and Drowsiness (Side Effect) is caused by Diazepam (Compound)
Trimethobenzamide may cause a moderate interaction that could exacerbate diseases when taken with Quazepam and Quazepam (Compound) resembles Flunitrazepam (Compound) and Flunitrazepam (Compound) resembles Diazepam (Compound)
Trimethobenzamide may cause a moderate interaction that could exacerbate diseases when taken with Oxazepam and Oxazepam (Compound) resembles Bromazepam (Compound) and Bromazepam (Compound) resembles Diazepam (Compound)
Trimethobenzamide may cause a moderate interaction that could exacerbate diseases when taken with Clomipramine and Clomipramine (Compound) resembles Adinazolam (Compound) and Adinazolam (Compound) resembles Diazepam (Compound)
Trimethobenzamide may cause a moderate interaction that could exacerbate diseases when taken with Lorazepam and Lorazepam (Compound) resembles Quazepam (Compound) and Quazepam (Compound) resembles Diazepam (Compound)
Trimethobenzamide may cause a moderate interaction that could exacerbate diseases when taken with Alprazolam and Alprazolam (Compound) resembles Quazepam (Compound) and Quazepam (Compound) resembles Diazepam (Compound)