DDInter364 DDInter808
Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor. Sulfonylureas also increase peripheral glucose utilization, decrease hepatic gluconeogenesis and may increase the number and sensitivity of insulin receptors. Sulfonylureas are associated with weight gain, though less so than insulin. Due to their mechanism of action, sulfonylureas may cause hypoglycemia and require consistent food intake to decrease this risk. The risk of hypoglycemia is increased in elderly, deb
Garlic allergenic extract is used in allergenic testing.
Chlorpropamide {u} (Compound) resembles {v} (Compound) Sulfacetamide
Chlorpropamide {u} (Compound) resembles {v} (Compound) Gliclazide
Chlorpropamide {u} (Compound) treats {v} (Disease) type 2 diabetes mellitus
Chlorpropamide {u} (Compound) binds {v} (Gene) SLC15A1
Chlorpropamide {u} (Compound) is included by {v} (Pharmacologic Class) Sulfonylurea Compounds
Chlorpropamide {u} (Compound) causes {v} (Side Effect) Water retention
Chlorpropamide (Compound) resembles Sulfacetamide (Compound)
Chlorpropamide (Compound) resembles Gliclazide (Compound)
Chlorpropamide (Compound) treats type 2 diabetes mellitus (Disease)
Chlorpropamide (Compound) binds SLC15A1 (Gene)
Chlorpropamide (Compound) is included by Sulfonylurea Compounds (Pharmacologic Class)
Chlorpropamide (Compound) causes Water retention (Side Effect)