DDInter1662 DDInter1118
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before beneficial effects are noticed. Sertraline displays enhanced safety or tolerability than other classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and other undesirable effects.[A1846,A187075,T28]
Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used commercially as a fire retardant. It can also be used topically as a deodorant or for the relief of canker sores (aphthous ulcers).
Sertraline {u} (Compound) binds {v} (Gene) CYP2C19
CYP2C19 {u} (Gene) is bound by {v} (Compound) Quazepam
Quazepam {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium hydroxide
Sertraline {u} (Compound) causes {v} (Side Effect) Dyspepsia
Dyspepsia {u} (Side Effect) is caused by {v} (Compound) Quazepam
Quazepam {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium hydroxide
Sertraline {u} (Compound) binds {v} (Gene) CYP2C9
CYP2C9 {u} (Gene) is bound by {v} (Compound) Diclofenamide
Diclofenamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Magnesium hydroxide
Sertraline {u} (Compound) downregulates {v} (Gene) RRP8
RRP8 {u} (Gene) is upregulated by {v} (Compound) Digitoxin
Digitoxin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium hydroxide
Sertraline {u} (Compound) upregulates {v} (Gene) MCOLN1
MCOLN1 {u} (Gene) is upregulated by {v} (Compound) Digitoxin
Digitoxin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium hydroxide
Sertraline {u} (Compound) causes {v} (Side Effect) Thinking abnormal
Thinking abnormal {u} (Side Effect) is caused by {v} (Compound) Salbutamol
Salbutamol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Magnesium hydroxide
Sertraline {u} (Compound) downregulates {v} (Gene) RRP8
RRP8 {u} (Gene) is upregulated by {v} (Compound) Betamethasone
Betamethasone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Magnesium hydroxide
Sertraline {u} (Compound) upregulates {v} (Gene) NPC1
NPC1 {u} (Gene) is downregulated by {v} (Compound) Captopril
Captopril {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium hydroxide
Sertraline {u} (Compound) downregulates {v} (Gene) JMJD6
JMJD6 {u} (Gene) is downregulated by {v} (Compound) Ponatinib
Ponatinib {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium hydroxide
Sertraline {u} (Compound) downregulates {v} (Gene) JMJD6
JMJD6 {u} (Gene) is downregulated by {v} (Compound) Vemurafenib
Vemurafenib {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Magnesium hydroxide
Sertraline (Compound) binds CYP2C19 (Gene) and CYP2C19 (Gene) is bound by Quazepam (Compound) and Quazepam may cause a minor interaction that can limit clinical effects when taken with Magnesium hydroxide
Sertraline (Compound) causes Dyspepsia (Side Effect) and Dyspepsia (Side Effect) is caused by Quazepam (Compound) and Quazepam may cause a minor interaction that can limit clinical effects when taken with Magnesium hydroxide
Sertraline (Compound) binds CYP2C9 (Gene) and CYP2C9 (Gene) is bound by Diclofenamide (Compound) and Diclofenamide may cause a moderate interaction that could exacerbate diseases when taken with Magnesium hydroxide
Sertraline (Compound) downregulates RRP8 (Gene) and RRP8 (Gene) is upregulated by Digitoxin (Compound) and Digitoxin may cause a minor interaction that can limit clinical effects when taken with Magnesium hydroxide
Sertraline (Compound) upregulates MCOLN1 (Gene) and MCOLN1 (Gene) is upregulated by Digitoxin (Compound) and Digitoxin may cause a minor interaction that can limit clinical effects when taken with Magnesium hydroxide
Sertraline (Compound) causes Thinking abnormal (Side Effect) and Thinking abnormal (Side Effect) is caused by Salbutamol (Compound) and Salbutamol may cause a moderate interaction that could exacerbate diseases when taken with Magnesium hydroxide
Sertraline (Compound) downregulates RRP8 (Gene) and RRP8 (Gene) is upregulated by Betamethasone (Compound) and Betamethasone may cause a moderate interaction that could exacerbate diseases when taken with Magnesium hydroxide
Sertraline (Compound) upregulates NPC1 (Gene) and NPC1 (Gene) is downregulated by Captopril (Compound) and Captopril may cause a minor interaction that can limit clinical effects when taken with Magnesium hydroxide
Sertraline (Compound) downregulates JMJD6 (Gene) and JMJD6 (Gene) is downregulated by Ponatinib (Compound) and Ponatinib may cause a minor interaction that can limit clinical effects when taken with Magnesium hydroxide
Sertraline (Compound) downregulates JMJD6 (Gene) and JMJD6 (Gene) is downregulated by Vemurafenib (Compound) and Vemurafenib may cause a moderate interaction that could exacerbate diseases when taken with Magnesium hydroxide