DDInter690 DDInter243
A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.
Bromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity. It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia. Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as well as the treatment of acromegaly. Bromocriptine has been associated with pulmonary fibrosis, and can also cause sustained suppression of somatotropin (growth hormone) secretion in some patients with acromegaly. In 1995, the FDA withdrew the approval of bromocriptine mesylate for the prevention of physiological lactation after finding that bromocriptine was not shown to be safe for use.[L43942,L43947] It continues to be used for the indications mentioned above.
Ethanol {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Bromocriptine
Ethanol {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Ergoloid mesylate
Ergoloid mesylate {u} (Compound) resembles {v} (Compound) Bromocriptine
Ethanol {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Diphenhydramine
Diphenhydramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Bromocriptine
Ethanol {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Tamoxifen
Tamoxifen {u} may cause a minor interaction that can limit clinical effects when taken with {v} Bromocriptine
Ethanol {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is associated with {v} (Disease) type 2 diabetes mellitus
type 2 diabetes mellitus {u} (Disease) is treated by {v} (Compound) Bromocriptine
Ethanol {u} (Compound) binds {v} (Gene) CYP2C19
CYP2C19 {u} (Gene) covaries with {v} (Gene) PAK1
PAK1 {u} (Gene) is upregulated by {v} (Compound) Bromocriptine
Ethanol {u} (Compound) binds {v} (Gene) CYP2E1
CYP2E1 {u} (Gene) is associated with {v} (Disease) Parkinson's disease
Parkinson's disease {u} (Disease) is palliated by {v} (Compound) Bromocriptine
Ethanol {u} (Compound) binds {v} (Gene) GABRA1
GABRA1 {u} (Gene) interacts with {v} (Gene) DRD4
DRD4 {u} (Gene) is bound by {v} (Compound) Bromocriptine
Ethanol {u} (Compound) binds {v} (Gene) CYP1A1
CYP1A1 {u} (Gene) regulates {v} (Gene) NUCB2
NUCB2 {u} (Gene) is upregulated by {v} (Compound) Bromocriptine
Ethanol {u} (Compound) binds {v} (Gene) CYP1A1
CYP1A1 {u} (Gene) regulates {v} (Gene) PCNA
PCNA {u} (Gene) is downregulated by {v} (Compound) Bromocriptine
Ethanol (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Bromocriptine (Compound)
Ethanol (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Ergoloid mesylate (Compound) and Ergoloid mesylate (Compound) resembles Bromocriptine (Compound)
Ethanol (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Diphenhydramine (Compound) and Diphenhydramine may cause a moderate interaction that could exacerbate diseases when taken with Bromocriptine
Ethanol (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Tamoxifen (Compound) and Tamoxifen may cause a minor interaction that can limit clinical effects when taken with Bromocriptine
Ethanol (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is associated with type 2 diabetes mellitus (Disease) and type 2 diabetes mellitus (Disease) is treated by Bromocriptine (Compound)
Ethanol (Compound) binds CYP2C19 (Gene) and CYP2C19 (Gene) covaries with PAK1 (Gene) and PAK1 (Gene) is upregulated by Bromocriptine (Compound)
Ethanol (Compound) binds CYP2E1 (Gene) and CYP2E1 (Gene) is associated with Parkinson's disease (Disease) and Parkinson's disease (Disease) is palliated by Bromocriptine (Compound)
Ethanol (Compound) binds GABRA1 (Gene) and GABRA1 (Gene) interacts with DRD4 (Gene) and DRD4 (Gene) is bound by Bromocriptine (Compound)
Ethanol (Compound) binds CYP1A1 (Gene) and CYP1A1 (Gene) regulates NUCB2 (Gene) and NUCB2 (Gene) is upregulated by Bromocriptine (Compound)
Ethanol (Compound) binds CYP1A1 (Gene) and CYP1A1 (Gene) regulates PCNA (Gene) and PCNA (Gene) is downregulated by Bromocriptine (Compound)