DDInter569 DDInter981
Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269, F3352]. As histamine receptors exist both peripherally and in the central nervous system, diphenhydramine has been shown to cause sedation due to its competitive antagonism of histamine H1 receptors within the central nervous system [L5263, L5266, L5269, F3379, A174541]. While its use in allergy therapy can sometimes fall out of favor due to its sedative effect, diphenhydramine has been repurposed
Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor. It is used in the treatment of major depression, dysthymic disorder, atypical disorder, panic disorder and the phobic disorders. It was first introduced by Roche pharmaceuticals, further developed by Validus pharms Inc and first FDA approved as a prescription drug on July 1st, 1959.
Diphenhydramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenacemide
Phenacemide {u} (Compound) resembles {v} (Compound) Isocarboxazid
Diphenhydramine {u} (Compound) causes {v} (Side Effect) Somnolence
Somnolence {u} (Side Effect) is caused by {v} (Compound) Isocarboxazid
Diphenhydramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenacemide
Phenacemide {u} (Compound) resembles {v} (Compound) Lacosamide
Lacosamide {u} (Compound) resembles {v} (Compound) Isocarboxazid
Diphenhydramine {u} (Compound) causes {v} (Side Effect) Somnolence
Somnolence {u} (Side Effect) is caused by {v} (Compound) Lacosamide
Lacosamide {u} (Compound) resembles {v} (Compound) Isocarboxazid
Diphenhydramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenelzine
Phenelzine {u} (Compound) resembles {v} (Compound) Phenacemide
Phenacemide {u} (Compound) resembles {v} (Compound) Isocarboxazid
Diphenhydramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenacemide
Phenacemide {u} (Compound) resembles {v} (Compound) Benzyl alcohol
Benzyl alcohol {u} (Compound) resembles {v} (Compound) Isocarboxazid
Diphenhydramine {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Metamfetamine
Metamfetamine {u} (Compound) resembles {v} (Compound) Isocarboxazid
Diphenhydramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Guanfacine
Guanfacine {u} (Compound) resembles {v} (Compound) Phenacemide
Phenacemide {u} (Compound) resembles {v} (Compound) Isocarboxazid
Diphenhydramine {u} (Compound) resembles {v} (Compound) Benzyl Benzoate
Benzyl Benzoate {u} (Compound) resembles {v} (Compound) Phenacemide
Phenacemide {u} (Compound) resembles {v} (Compound) Isocarboxazid
Diphenhydramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Guanfacine
Guanfacine {u} (Compound) causes {v} (Side Effect) Somnolence
Somnolence {u} (Side Effect) is caused by {v} (Compound) Isocarboxazid
Diphenhydramine may cause a moderate interaction that could exacerbate diseases when taken with Phenacemide and Phenacemide (Compound) resembles Isocarboxazid (Compound)
Diphenhydramine (Compound) causes Somnolence (Side Effect) and Somnolence (Side Effect) is caused by Isocarboxazid (Compound)
Diphenhydramine may cause a moderate interaction that could exacerbate diseases when taken with Phenacemide and Phenacemide (Compound) resembles Lacosamide (Compound) and Lacosamide (Compound) resembles Isocarboxazid (Compound)
Diphenhydramine (Compound) causes Somnolence (Side Effect) and Somnolence (Side Effect) is caused by Lacosamide (Compound) and Lacosamide (Compound) resembles Isocarboxazid (Compound)
Diphenhydramine may cause a moderate interaction that could exacerbate diseases when taken with Phenelzine and Phenelzine (Compound) resembles Phenacemide (Compound) and Phenacemide (Compound) resembles Isocarboxazid (Compound)
Diphenhydramine may cause a moderate interaction that could exacerbate diseases when taken with Phenacemide and Phenacemide (Compound) resembles Benzyl alcohol (Compound) and Benzyl alcohol (Compound) resembles Isocarboxazid (Compound)
Diphenhydramine (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Metamfetamine (Compound) and Metamfetamine (Compound) resembles Isocarboxazid (Compound)
Diphenhydramine may cause a moderate interaction that could exacerbate diseases when taken with Guanfacine and Guanfacine (Compound) resembles Phenacemide (Compound) and Phenacemide (Compound) resembles Isocarboxazid (Compound)
Diphenhydramine (Compound) resembles Benzyl Benzoate (Compound) and Benzyl Benzoate (Compound) resembles Phenacemide (Compound) and Phenacemide (Compound) resembles Isocarboxazid (Compound)
Diphenhydramine may cause a moderate interaction that could exacerbate diseases when taken with Guanfacine and Guanfacine (Compound) causes Somnolence (Side Effect) and Somnolence (Side Effect) is caused by Isocarboxazid (Compound)