DDInter1938 DDInter666
Vincristine is a vinca alkaloid with formula C46H56N4O10 found in the Madagascar periwinkle, Catharanthus roseus. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer. It has a role as a tubulin modulator, a microtubule-destabilising agent, a plant metabolite, an antineoplastic agent and a drug. It is a methyl ester, an acetate ester, a tertiary alcohol, a member of formamides, an organic heteropentacyclic compound, an organic heterotetracyclic compound, a tertiary amino compound and a vinca alkaloid. It is a conjugate base of a vincristine(2+). It derives from a hydride of a vincaleukoblastine.
Eribulin is a microtubule inhibitor indicated for the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic disease. Eribulin was isolated from the marine sponge Halichondria okadai. Eribulin is also being investigated for use in the treatment of advanced solid tumors .
Vincristine {u} (Compound) binds {v} (Gene) TUBB
TUBB {u} (Gene) is bound by {v} (Compound) Eribulin
Vincristine {u} (Compound) binds {v} (Gene) and {u} (Compound) upregulates {v} (Gene) TUBB6
TUBB6 {u} (Gene) is bound by {v} (Compound) Eribulin
Vincristine {u} (Compound) resembles {v} (Compound) Vinblastine
Vinblastine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eribulin
Vincristine {u} (Compound) resembles {v} (Compound) Vinorelbine
Vinorelbine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eribulin
Vincristine {u} (Compound) binds {v} (Gene) TUBB
TUBB {u} (Gene) is bound by {v} (Compound) Paclitaxel
Paclitaxel {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eribulin
Vincristine {u} (Compound) binds {v} (Gene) and {u} (Compound) upregulates {v} (Gene) TUBB6
TUBB6 {u} (Gene) is regulated by {v} (Gene) TUBB2A
TUBB2A {u} (Gene) is bound by {v} (Compound) Eribulin
Vincristine {u} (Compound) binds {v} (Gene) and {u} (Compound) upregulates {v} (Gene) TUBB2A
TUBB2A {u} (Gene) regulates {v} (Gene) TUBB6
TUBB6 {u} (Gene) is bound by {v} (Compound) Eribulin
Vincristine {u} (Compound) binds {v} (Gene) TUBB3
TUBB3 {u} (Gene) is associated with {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Eribulin
Vincristine {u} (Compound) resembles {v} (Compound) Vinblastine
Vinblastine {u} (Compound) treats {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Eribulin
Vincristine {u} (Compound) upregulates {v} (Gene) INPP1
INPP1 {u} (Gene) is downregulated by {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Eribulin
Vincristine (Compound) binds TUBB (Gene) and TUBB (Gene) is bound by Eribulin (Compound)
Vincristine (Compound) binds TUBB6 (Gene) and Vincristine (Compound) upregulates TUBB6 (Gene) and TUBB6 (Gene) is bound by Eribulin (Compound)
Vincristine (Compound) resembles Vinblastine (Compound) and Vinblastine may cause a moderate interaction that could exacerbate diseases when taken with Eribulin
Vincristine (Compound) resembles Vinorelbine (Compound) and Vinorelbine may cause a moderate interaction that could exacerbate diseases when taken with Eribulin
Vincristine (Compound) binds TUBB (Gene) and TUBB (Gene) is bound by Paclitaxel (Compound) and Paclitaxel may cause a moderate interaction that could exacerbate diseases when taken with Eribulin
Vincristine (Compound) binds TUBB6 (Gene) and Vincristine (Compound) upregulates TUBB6 (Gene) and TUBB6 (Gene) is regulated by TUBB2A (Gene) and TUBB2A (Gene) is bound by Eribulin (Compound)
Vincristine (Compound) binds TUBB2A (Gene) and Vincristine (Compound) upregulates TUBB2A (Gene) and TUBB2A (Gene) regulates TUBB6 (Gene) and TUBB6 (Gene) is bound by Eribulin (Compound)
Vincristine (Compound) binds TUBB3 (Gene) and TUBB3 (Gene) is associated with breast cancer (Disease) and breast cancer (Disease) is treated by Eribulin (Compound)
Vincristine (Compound) resembles Vinblastine (Compound) and Vinblastine (Compound) treats breast cancer (Disease) and breast cancer (Disease) is treated by Eribulin (Compound)
Vincristine (Compound) upregulates INPP1 (Gene) and INPP1 (Gene) is downregulated by breast cancer (Disease) and breast cancer (Disease) is treated by Eribulin (Compound)