DDInter336 DDInter897
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in the colon. It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval in 1998. Interestingly, selective COX-2 inhibitors (especially celecoxib), have been evaluated as potential cancer chemopreventive and therapeutic drugs in clinical trials for a variety of malignancies.
Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to [zoledronic acid], [minodronic acid], and [risedronic acid].[A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs. Ibandronate was granted FDA approval on 16 May 2003.
Celecoxib {u} (Compound) causes {v} (Side Effect) Renal failure acute
Renal failure acute {u} (Side Effect) is caused by {v} (Compound) Ibandronate
Celecoxib {u} (Compound) causes {v} (Side Effect) Renal failure acute
Renal failure acute {u} (Side Effect) is caused by {v} (Compound) Zoledronic acid
Zoledronic acid {u} (Compound) resembles {v} (Compound) Ibandronate
Celecoxib {u} (Compound) causes {v} (Side Effect) Bladder pain
Bladder pain {u} (Side Effect) is caused by {v} (Compound) Risedronic acid
Risedronic acid {u} (Compound) resembles {v} (Compound) Ibandronate
Celecoxib {u} (Compound) causes {v} (Side Effect) Deafness
Deafness {u} (Side Effect) is caused by {v} (Compound) Vancomycin
Vancomycin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ibandronate
Celecoxib {u} (Compound) causes {v} (Side Effect) Migraine
Migraine {u} (Side Effect) is caused by {v} (Compound) Thalidomide
Thalidomide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ibandronate
Celecoxib {u} (Compound) causes {v} (Side Effect) Cerebrovascular disorder
Cerebrovascular disorder {u} (Side Effect) is caused by {v} (Compound) Iodixanol
Iodixanol {u} may lead to a major life threatening interaction when taken with {v} Ibandronate
Celecoxib {u} (Compound) resembles {v} (Compound) Sulfaphenazole
Sulfaphenazole {u} (Compound) resembles {v} (Compound) Sulfasalazine
Sulfasalazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ibandronate
Celecoxib {u} (Compound) resembles {v} (Compound) Etoricoxib
Etoricoxib {u} (Compound) causes {v} (Side Effect) Bronchitis
Bronchitis {u} (Side Effect) is caused by {v} (Compound) Ibandronate
Celecoxib {u} (Compound) binds {v} (Gene) CA14
CA14 {u} (Gene) is bound by {v} (Compound) Zoledronic acid
Zoledronic acid {u} (Compound) resembles {v} (Compound) Ibandronate
Celecoxib {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Ibuprofen
Ibuprofen {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ibandronate
Celecoxib (Compound) causes Renal failure acute (Side Effect) and Renal failure acute (Side Effect) is caused by Ibandronate (Compound)
Celecoxib (Compound) causes Renal failure acute (Side Effect) and Renal failure acute (Side Effect) is caused by Zoledronic acid (Compound) and Zoledronic acid (Compound) resembles Ibandronate (Compound)
Celecoxib (Compound) causes Bladder pain (Side Effect) and Bladder pain (Side Effect) is caused by Risedronic acid (Compound) and Risedronic acid (Compound) resembles Ibandronate (Compound)
Celecoxib (Compound) causes Deafness (Side Effect) and Deafness (Side Effect) is caused by Vancomycin (Compound) and Vancomycin may cause a moderate interaction that could exacerbate diseases when taken with Ibandronate
Celecoxib (Compound) causes Migraine (Side Effect) and Migraine (Side Effect) is caused by Thalidomide (Compound) and Thalidomide may cause a moderate interaction that could exacerbate diseases when taken with Ibandronate
Celecoxib (Compound) causes Cerebrovascular disorder (Side Effect) and Cerebrovascular disorder (Side Effect) is caused by Iodixanol (Compound) and Iodixanol may lead to a major life threatening interaction when taken with Ibandronate
Celecoxib (Compound) resembles Sulfaphenazole (Compound) and Sulfaphenazole (Compound) resembles Sulfasalazine (Compound) and Sulfasalazine may cause a moderate interaction that could exacerbate diseases when taken with Ibandronate
Celecoxib (Compound) resembles Etoricoxib (Compound) and Etoricoxib (Compound) causes Bronchitis (Side Effect) and Bronchitis (Side Effect) is caused by Ibandronate (Compound)
Celecoxib (Compound) binds CA14 (Gene) and CA14 (Gene) is bound by Zoledronic acid (Compound) and Zoledronic acid (Compound) resembles Ibandronate (Compound)
Celecoxib (Compound) binds ALB (Gene) and ALB (Gene) is bound by Ibuprofen (Compound) and Ibuprofen may cause a moderate interaction that could exacerbate diseases when taken with Ibandronate