DDInter1620 DDInter1955
Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.
Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once daily. Zafirlukast blocks the action of the cysteinyl leukotrienes on the CysLT1 receptors, thus reducing constriction of the airways, build-up of mucus in the lungs and inflammation of the breathing passages.
Ropivacaine {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Zafirlukast
Ropivacaine {u} (Compound) causes {v} (Side Effect) Insomnia
Insomnia {u} (Side Effect) is caused by {v} (Compound) Zafirlukast
Ropivacaine {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Citalopram
Citalopram {u} may cause a minor interaction that can limit clinical effects when taken with {v} Zafirlukast
Ropivacaine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Tolvaptan
Tolvaptan {u} (Compound) resembles {v} (Compound) Zafirlukast
Ropivacaine {u} (Compound) causes {v} (Side Effect) Insomnia
Insomnia {u} (Side Effect) is caused by {v} (Compound) Donepezil
Donepezil {u} may cause a minor interaction that can limit clinical effects when taken with {v} Zafirlukast
Ropivacaine {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Tolvaptan
Tolvaptan {u} (Compound) resembles {v} (Compound) Zafirlukast
Ropivacaine {u} (Compound) causes {v} (Side Effect) Neuropathy
Neuropathy {u} (Side Effect) is caused by {v} (Compound) Citalopram
Citalopram {u} may cause a minor interaction that can limit clinical effects when taken with {v} Zafirlukast
Ropivacaine {u} (Compound) resembles {v} (Compound) Lidocaine
Lidocaine {u} (Compound) binds {v} (Gene) CYP2C9
CYP2C9 {u} (Gene) is bound by {v} (Compound) Zafirlukast
Ropivacaine {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Modafinil
Modafinil {u} may cause a minor interaction that can limit clinical effects when taken with {v} Zafirlukast
Ropivacaine {u} (Compound) causes {v} (Side Effect) Neuropathy
Neuropathy {u} (Side Effect) is caused by {v} (Compound) Bortezomib
Bortezomib {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Zafirlukast
Ropivacaine (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Zafirlukast (Compound)
Ropivacaine (Compound) causes Insomnia (Side Effect) and Insomnia (Side Effect) is caused by Zafirlukast (Compound)
Ropivacaine (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Citalopram (Compound) and Citalopram may cause a minor interaction that can limit clinical effects when taken with Zafirlukast
Ropivacaine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Tolvaptan (Compound) and Tolvaptan (Compound) resembles Zafirlukast (Compound)
Ropivacaine (Compound) causes Insomnia (Side Effect) and Insomnia (Side Effect) is caused by Donepezil (Compound) and Donepezil may cause a minor interaction that can limit clinical effects when taken with Zafirlukast
Ropivacaine (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Tolvaptan (Compound) and Tolvaptan (Compound) resembles Zafirlukast (Compound)
Ropivacaine (Compound) causes Neuropathy (Side Effect) and Neuropathy (Side Effect) is caused by Citalopram (Compound) and Citalopram may cause a minor interaction that can limit clinical effects when taken with Zafirlukast
Ropivacaine (Compound) resembles Lidocaine (Compound) and Lidocaine (Compound) binds CYP2C9 (Gene) and CYP2C9 (Gene) is bound by Zafirlukast (Compound)
Ropivacaine (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Modafinil (Compound) and Modafinil may cause a minor interaction that can limit clinical effects when taken with Zafirlukast
Ropivacaine (Compound) causes Neuropathy (Side Effect) and Neuropathy (Side Effect) is caused by Bortezomib (Compound) and Bortezomib may cause a moderate interaction that could exacerbate diseases when taken with Zafirlukast