DDInter350 DDInter460
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)
Chlorambucil {u} (Compound) treats {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is treated by {v} (Compound) Cytarabine
Chlorambucil {u} (Compound) upregulates {v} (Gene) INPP1
INPP1 {u} (Gene) is upregulated by {v} (Compound) Cytarabine
Chlorambucil {u} (Compound) downregulates {v} (Gene) UBE2C
UBE2C {u} (Gene) is downregulated by {v} (Compound) Cytarabine
Chlorambucil {u} (Compound) resembles {v} (Compound) Melphalan
Melphalan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cytarabine
Chlorambucil {u} (Compound) treats {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is treated by {v} (Compound) Nelarabine
Nelarabine {u} (Compound) resembles {v} (Compound) Cytarabine
Chlorambucil {u} (Compound) upregulates {v} (Gene) INPP1
INPP1 {u} (Gene) is upregulated by {v} (Compound) Gemcitabine
Gemcitabine {u} (Compound) resembles {v} (Compound) Cytarabine
Chlorambucil {u} (Compound) downregulates {v} (Gene) UBE2C
UBE2C {u} (Gene) is downregulated by {v} (Compound) Gemcitabine
Gemcitabine {u} (Compound) resembles {v} (Compound) Cytarabine
Chlorambucil {u} (Compound) treats {v} (Disease) ovarian cancer
ovarian cancer {u} (Disease) is treated by {v} (Compound) Epirubicin
Epirubicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cytarabine
Chlorambucil {u} (Compound) resembles {v} (Compound) Melphalan
Melphalan {u} (Compound) treats {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is treated by {v} (Compound) Cytarabine
Chlorambucil {u} (Compound) treats {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is treated by {v} (Compound) Gemcitabine
Gemcitabine {u} (Compound) resembles {v} (Compound) Cytarabine
Chlorambucil (Compound) treats hematologic cancer (Disease) and hematologic cancer (Disease) is treated by Cytarabine (Compound)
Chlorambucil (Compound) upregulates INPP1 (Gene) and INPP1 (Gene) is upregulated by Cytarabine (Compound)
Chlorambucil (Compound) downregulates UBE2C (Gene) and UBE2C (Gene) is downregulated by Cytarabine (Compound)
Chlorambucil (Compound) resembles Melphalan (Compound) and Melphalan may cause a moderate interaction that could exacerbate diseases when taken with Cytarabine
Chlorambucil (Compound) treats hematologic cancer (Disease) and hematologic cancer (Disease) is treated by Nelarabine (Compound) and Nelarabine (Compound) resembles Cytarabine (Compound)
Chlorambucil (Compound) upregulates INPP1 (Gene) and INPP1 (Gene) is upregulated by Gemcitabine (Compound) and Gemcitabine (Compound) resembles Cytarabine (Compound)
Chlorambucil (Compound) downregulates UBE2C (Gene) and UBE2C (Gene) is downregulated by Gemcitabine (Compound) and Gemcitabine (Compound) resembles Cytarabine (Compound)
Chlorambucil (Compound) treats ovarian cancer (Disease) and ovarian cancer (Disease) is treated by Epirubicin (Compound) and Epirubicin may cause a moderate interaction that could exacerbate diseases when taken with Cytarabine
Chlorambucil (Compound) resembles Melphalan (Compound) and Melphalan (Compound) treats hematologic cancer (Disease) and hematologic cancer (Disease) is treated by Cytarabine (Compound)
Chlorambucil (Compound) treats hematologic cancer (Disease) and hematologic cancer (Disease) is treated by Gemcitabine (Compound) and Gemcitabine (Compound) resembles Cytarabine (Compound)