DDInter738 DDInter1544
A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties. The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies. Prucalopride was developed by Shire Development LLC and approved for use in Europe in 2009, in Canada on December 7, 2011 and by the FDA on December 17, 2018.
Flavoxate {u} (Compound) resembles {v} (Compound) Pipazethate
Flavoxate {u} (Compound) resembles {v} (Compound) Raloxifene
Flavoxate {u} (Compound) binds {v} (Gene) PDE4B
Flavoxate {u} (Compound) upregulates {v} (Gene) GPATCH8
Flavoxate {u} (Compound) is included by {v} (Pharmacologic Class) Cholinergic Muscarinic Antagonists
Flavoxate {u} (Compound) downregulates {v} (Gene) ACAT2
Flavoxate {u} (Compound) causes {v} (Side Effect) Hyperpyrexia
Flavoxate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cyclizine
Flavoxate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Propantheline
Flavoxate {u} may lead to a major life threatening interaction when taken with {v} Potassium chloride
Flavoxate (Compound) resembles Pipazethate (Compound)
Flavoxate (Compound) resembles Raloxifene (Compound)
Flavoxate (Compound) binds PDE4B (Gene)
Flavoxate (Compound) upregulates GPATCH8 (Gene)
Flavoxate (Compound) is included by Cholinergic Muscarinic Antagonists (Pharmacologic Class)
Flavoxate (Compound) downregulates ACAT2 (Gene)
Flavoxate (Compound) causes Hyperpyrexia (Side Effect)
Flavoxate may cause a moderate interaction that could exacerbate diseases when taken with Cyclizine
Flavoxate may cause a moderate interaction that could exacerbate diseases when taken with Propantheline
Flavoxate may lead to a major life threatening interaction when taken with Potassium chloride