DDInter268 DDInter257
Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D<sub>3</sub>, 1,25-dihydroxyvitamin D<sub>3</sub>. It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to (vitamin D3) in the skin, which is then converted to in the liver and kidneys. undergoes hydroxylation to form calcitriol via 1α-hydroxylase (CYP27B1) activity. Calcitriol is considered to be the most potent metabolite of vitamin D in humans. Renal production of calcitriol is stimulated in response to PTH
Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. It is a short-to-intermediate acting member of barbiturates that exhibit muscle-relaxing and anti-anxiety properties that produce central nervous system (CNS) depression that ranges from mild sedation to general anesthesia. Butalbital has a low degree of selectivity and a narrow therapeutic index. Typically indicated to manage tension (or muscle contraction) headaches, butalbital is often combined with one or more therapeutic agents, such as acetylsalicylic acid, acetaminophen, aspirin, and caffeine. There have not been clinical trials that evaluate the clinical efficacy of butalbital in migraines thus it is not indicated for such condition. As with other barbiturates, butalbital carries a risk of abuse or misuse potential, intoxication, hangover, tolerance, dependence, and overdosage possibly leading to death. Butalbital‐containing analgesics can also produce a drug‐induced headache in addition to tolerance and dependence. Due to these risks, the use of butalbital-containing combination products is typically limited for use only in cases where other medications are deemed ineffective and such usage is advised to be carefully monitored.
Calcitriol {u} (Compound) resembles {v} (Compound) Calcifediol
Calcifediol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Butalbital
Calcitriol {u} (Compound) resembles {v} (Compound) Dihydrotachysterol
Dihydrotachysterol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Butalbital
Calcitriol {u} (Compound) resembles {v} (Compound) Calcifediol
Calcifediol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pentobarbital
Pentobarbital {u} (Compound) resembles {v} (Compound) Butalbital
Calcitriol {u} (Compound) resembles {v} (Compound) Dihydrotachysterol
Dihydrotachysterol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pentobarbital
Pentobarbital {u} (Compound) resembles {v} (Compound) Butalbital
Calcitriol {u} (Compound) causes {v} (Side Effect) Agitation
Agitation {u} (Side Effect) is caused by {v} (Compound) Butabarbital
Butabarbital {u} (Compound) resembles {v} (Compound) Butalbital
Calcitriol {u} (Compound) resembles {v} (Compound) Calcifediol
Calcifediol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Secobarbital
Secobarbital {u} (Compound) resembles {v} (Compound) Butalbital
Calcitriol {u} (Compound) resembles {v} (Compound) Dihydrotachysterol
Dihydrotachysterol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Secobarbital
Secobarbital {u} (Compound) resembles {v} (Compound) Butalbital
Calcitriol {u} (Compound) resembles {v} (Compound) Calcifediol
Calcifediol {u} may lead to a major life threatening interaction when taken with {v} Doxercalciferol
Doxercalciferol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Butalbital
Calcitriol {u} (Compound) resembles {v} (Compound) Dihydrotachysterol
Dihydrotachysterol {u} may lead to a major life threatening interaction when taken with {v} Calcifediol
Calcifediol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Butalbital
Calcitriol {u} (Compound) resembles {v} (Compound) Paricalcitol
Paricalcitol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ribociclib
Ribociclib {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Butalbital
Calcitriol (Compound) resembles Calcifediol (Compound) and Calcifediol may cause a moderate interaction that could exacerbate diseases when taken with Butalbital
Calcitriol (Compound) resembles Dihydrotachysterol (Compound) and Dihydrotachysterol may cause a moderate interaction that could exacerbate diseases when taken with Butalbital
Calcitriol (Compound) resembles Calcifediol (Compound) and Calcifediol may cause a moderate interaction that could exacerbate diseases when taken with Pentobarbital and Pentobarbital (Compound) resembles Butalbital (Compound)
Calcitriol (Compound) resembles Dihydrotachysterol (Compound) and Dihydrotachysterol may cause a moderate interaction that could exacerbate diseases when taken with Pentobarbital and Pentobarbital (Compound) resembles Butalbital (Compound)
Calcitriol (Compound) causes Agitation (Side Effect) and Agitation (Side Effect) is caused by Butabarbital (Compound) and Butabarbital (Compound) resembles Butalbital (Compound)
Calcitriol (Compound) resembles Calcifediol (Compound) and Calcifediol may cause a moderate interaction that could exacerbate diseases when taken with Secobarbital and Secobarbital (Compound) resembles Butalbital (Compound)
Calcitriol (Compound) resembles Dihydrotachysterol (Compound) and Dihydrotachysterol may cause a moderate interaction that could exacerbate diseases when taken with Secobarbital and Secobarbital (Compound) resembles Butalbital (Compound)
Calcitriol (Compound) resembles Calcifediol (Compound) and Calcifediol may lead to a major life threatening interaction when taken with Doxercalciferol and Doxercalciferol may cause a moderate interaction that could exacerbate diseases when taken with Butalbital
Calcitriol (Compound) resembles Dihydrotachysterol (Compound) and Dihydrotachysterol may lead to a major life threatening interaction when taken with Calcifediol and Calcifediol may cause a moderate interaction that could exacerbate diseases when taken with Butalbital
Calcitriol (Compound) resembles Paricalcitol (Compound) and Paricalcitol may cause a moderate interaction that could exacerbate diseases when taken with Ribociclib and Ribociclib may cause a moderate interaction that could exacerbate diseases when taken with Butalbital