DDInter1397 DDInter407
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham.[L7712,L7715] A unique feature of this drug is that it is highly potent and selective in its inhibition of serotonin reuptake and has little effect on other neurotransmitters. Because of its potent inhibition of serotonin reuptake, paroxetine is more likely to cause withdrawal effects upon cessation. Paroxetine is well tolerated in most patients with a similar adverse effect profile to other members of its drug class. The controlled release formulation was designed to decrease the likelihood of nausea that is sometimes associated with paroxetine.[L7700,L7742]
Clofedanol is a centrally-acting cough suppressant available in Canada under the trade name Ulone. It is not available in the United States.
Paroxetine {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Diphenhydramine
Diphenhydramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clofedanol
Paroxetine {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Imipramine
Imipramine {u} (Compound) resembles {v} (Compound) Clofedanol
Paroxetine {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Diphenhydramine
Diphenhydramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clofedanol
Paroxetine {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Dextropropoxyphene
Dextropropoxyphene {u} (Compound) resembles {v} (Compound) Clofedanol
Paroxetine {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Clotrimazole
Clotrimazole {u} (Compound) resembles {v} (Compound) Clofedanol
Paroxetine {u} (Compound) causes {v} (Side Effect) Dysuria
Dysuria {u} (Side Effect) is caused by {v} (Compound) Tetrabenazine
Tetrabenazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clofedanol
Paroxetine {u} (Compound) causes {v} (Side Effect) Thrombocytopenia
Thrombocytopenia {u} (Side Effect) is caused by {v} (Compound) Toremifene
Toremifene {u} (Compound) resembles {v} (Compound) Clofedanol
Paroxetine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Tetrabenazine
Tetrabenazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clofedanol
Paroxetine {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Carbinoxamine
Carbinoxamine {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clofedanol
Paroxetine {u} (Compound) causes {v} (Side Effect) Extrasystoles
Extrasystoles {u} (Side Effect) is caused by {v} (Compound) Carbinoxamine
Carbinoxamine {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clofedanol
Paroxetine (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Diphenhydramine (Compound) and Diphenhydramine may cause a moderate interaction that could exacerbate diseases when taken with Clofedanol
Paroxetine (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Imipramine (Compound) and Imipramine (Compound) resembles Clofedanol (Compound)
Paroxetine (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Diphenhydramine (Compound) and Diphenhydramine may cause a moderate interaction that could exacerbate diseases when taken with Clofedanol
Paroxetine (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Dextropropoxyphene (Compound) and Dextropropoxyphene (Compound) resembles Clofedanol (Compound)
Paroxetine (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Clotrimazole (Compound) and Clotrimazole (Compound) resembles Clofedanol (Compound)
Paroxetine (Compound) causes Dysuria (Side Effect) and Dysuria (Side Effect) is caused by Tetrabenazine (Compound) and Tetrabenazine may cause a moderate interaction that could exacerbate diseases when taken with Clofedanol
Paroxetine (Compound) causes Thrombocytopenia (Side Effect) and Thrombocytopenia (Side Effect) is caused by Toremifene (Compound) and Toremifene (Compound) resembles Clofedanol (Compound)
Paroxetine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Tetrabenazine (Compound) and Tetrabenazine may cause a moderate interaction that could exacerbate diseases when taken with Clofedanol
Paroxetine (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Carbinoxamine (Compound) and Carbinoxamine (Compound) resembles Clofedanol (Compound) and Carbinoxamine may cause a moderate interaction that could exacerbate diseases when taken with Clofedanol
Paroxetine (Compound) causes Extrasystoles (Side Effect) and Extrasystoles (Side Effect) is caused by Carbinoxamine (Compound) and Carbinoxamine (Compound) resembles Clofedanol (Compound) and Carbinoxamine may cause a moderate interaction that could exacerbate diseases when taken with Clofedanol