DDInter690 DDInter1665
A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.
Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the United States. In October 2010, Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease.
Ethanol {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Sibutramine
Ethanol {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Diphenhydramine
Diphenhydramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sibutramine
Ethanol {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Verapamil
Verapamil {u} may cause a minor interaction that can limit clinical effects when taken with {v} Sibutramine
Ethanol {u} (Compound) binds {v} (Gene) CYP4A11
CYP4A11 {u} (Gene) is bound by {v} (Compound) Phenobarbital
Phenobarbital {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sibutramine
Ethanol {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Miconazole
Miconazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Sibutramine
Ethanol {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Phentermine
Phentermine {u} may lead to a major life threatening interaction when taken with {v} Sibutramine
Ethanol {u} (Compound) binds {v} (Gene) ADH1B
ADH1B {u} (Gene) is associated with {v} (Disease) obesity
obesity {u} (Disease) is treated by {v} (Compound) Sibutramine
Ethanol {u} (Compound) binds {v} (Gene) CYP1A1
CYP1A1 {u} (Gene) regulates {v} (Gene) MRPL19
MRPL19 {u} (Gene) is downregulated by {v} (Compound) Sibutramine
Ethanol {u} (Compound) binds {v} (Gene) GRIN3A
GRIN3A {u} (Gene) regulates {v} (Gene) CDK6
CDK6 {u} (Gene) is upregulated by {v} (Compound) Sibutramine
Ethanol {u} (Compound) binds {v} (Gene) CYP2E1
CYP2E1 {u} (Gene) is bound by {v} (Compound) Dexfenfluramine
Dexfenfluramine {u} may lead to a major life threatening interaction when taken with {v} Sibutramine
Ethanol (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Sibutramine (Compound)
Ethanol (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Diphenhydramine (Compound) and Diphenhydramine may cause a moderate interaction that could exacerbate diseases when taken with Sibutramine
Ethanol (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Verapamil (Compound) and Verapamil may cause a minor interaction that can limit clinical effects when taken with Sibutramine
Ethanol (Compound) binds CYP4A11 (Gene) and CYP4A11 (Gene) is bound by Phenobarbital (Compound) and Phenobarbital may cause a moderate interaction that could exacerbate diseases when taken with Sibutramine
Ethanol (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Miconazole (Compound) and Miconazole may cause a minor interaction that can limit clinical effects when taken with Sibutramine
Ethanol (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Phentermine (Compound) and Phentermine may lead to a major life threatening interaction when taken with Sibutramine
Ethanol (Compound) binds ADH1B (Gene) and ADH1B (Gene) is associated with obesity (Disease) and obesity (Disease) is treated by Sibutramine (Compound)
Ethanol (Compound) binds CYP1A1 (Gene) and CYP1A1 (Gene) regulates MRPL19 (Gene) and MRPL19 (Gene) is downregulated by Sibutramine (Compound)
Ethanol (Compound) binds GRIN3A (Gene) and GRIN3A (Gene) regulates CDK6 (Gene) and CDK6 (Gene) is upregulated by Sibutramine (Compound)
Ethanol (Compound) binds CYP2E1 (Gene) and CYP2E1 (Gene) is bound by Dexfenfluramine (Compound) and Dexfenfluramine may lead to a major life threatening interaction when taken with Sibutramine