DDInter850 DDInter1763
Halazepam is a _benzodiazepine_ derivative drug exerting anxiolytic, anticonvulsant, sedative, a muscle relaxing effects.[A1212, A178114] It has been shown to be less toxic than chlordiazepoxide or diazepam. This drug is no longer marketed in the United States, and was withdrawn by _Schering_, its manufacturer, in 2009.[L6226, L6229]
Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). It was developed by Wyeth Pharmaceuticals under the trade name Torisel. Temsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007.
Halazepam {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Halazepam {u} (Compound) resembles {v} (Compound) Oxazepam
Oxazepam {u} (Compound) binds {v} (Gene) CYP3A7
CYP3A7 {u} (Gene) is bound by {v} (Compound) Temsirolimus
Halazepam {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Everolimus
Everolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Halazepam {u} (Compound) resembles {v} (Compound) Triazolam
Triazolam {u} (Compound) binds {v} (Gene) CYP3A5
CYP3A5 {u} (Gene) is bound by {v} (Compound) Temsirolimus
Halazepam {u} (Compound) resembles {v} (Compound) Nitrazepam
Nitrazepam {u} (Compound) causes {v} (Side Effect) Convulsion
Convulsion {u} (Side Effect) is caused by {v} (Compound) Temsirolimus
Halazepam {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sirolimus
Sirolimus {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Temsirolimus
Halazepam {u} (Compound) resembles {v} (Compound) Clobazam
Clobazam {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Halazepam {u} (Compound) resembles {v} (Compound) Alprazolam
Alprazolam {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Halazepam {u} (Compound) resembles {v} (Compound) Clorazepic acid
Clorazepic acid {u} (Compound) causes {v} (Side Effect) Somnolence
Somnolence {u} (Side Effect) is caused by {v} (Compound) Temsirolimus
Halazepam {u} (Compound) resembles {v} (Compound) Alprazolam
Alprazolam {u} (Compound) downregulates {v} (Gene) MYC
MYC {u} (Gene) is upregulated by {v} (Compound) Temsirolimus
Halazepam may cause a moderate interaction that could exacerbate diseases when taken with Sirolimus and Sirolimus (Compound) resembles Temsirolimus (Compound)
Halazepam (Compound) resembles Oxazepam (Compound) and Oxazepam (Compound) binds CYP3A7 (Gene) and CYP3A7 (Gene) is bound by Temsirolimus (Compound)
Halazepam may cause a moderate interaction that could exacerbate diseases when taken with Sirolimus and Sirolimus (Compound) resembles Everolimus (Compound) and Everolimus (Compound) resembles Temsirolimus (Compound)
Halazepam (Compound) resembles Triazolam (Compound) and Triazolam (Compound) binds CYP3A5 (Gene) and CYP3A5 (Gene) is bound by Temsirolimus (Compound)
Halazepam (Compound) resembles Nitrazepam (Compound) and Nitrazepam (Compound) causes Convulsion (Side Effect) and Convulsion (Side Effect) is caused by Temsirolimus (Compound)
Halazepam may cause a moderate interaction that could exacerbate diseases when taken with Sirolimus and Sirolimus (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Temsirolimus (Compound)
Halazepam (Compound) resembles Clobazam (Compound) and Clobazam may cause a moderate interaction that could exacerbate diseases when taken with Sirolimus and Sirolimus (Compound) resembles Temsirolimus (Compound)
Halazepam (Compound) resembles Alprazolam (Compound) and Alprazolam may cause a moderate interaction that could exacerbate diseases when taken with Sirolimus and Sirolimus (Compound) resembles Temsirolimus (Compound)
Halazepam (Compound) resembles Clorazepic acid (Compound) and Clorazepic acid (Compound) causes Somnolence (Side Effect) and Somnolence (Side Effect) is caused by Temsirolimus (Compound)
Halazepam (Compound) resembles Alprazolam (Compound) and Alprazolam (Compound) downregulates MYC (Gene) and MYC (Gene) is upregulated by Temsirolimus (Compound)