DDInter1796 DDInter832
A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p618). Thioridazine was withdrawn worldwide in 2005 due to its association with cardiac arrythmias.
A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Thioridazine {u} (Compound) resembles {v} (Compound) Prochlorperazine
Thioridazine {u} (Compound) resembles {v} (Compound) Ethopropazine
Thioridazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clemastine
Thioridazine {u} (Compound) binds {v} (Gene) CYP2D6
Thioridazine {u} (Compound) upregulates {v} (Gene) KDM5B
Thioridazine {u} (Compound) palliates {v} (Disease) schizophrenia
Thioridazine {u} (Compound) is included by {v} (Pharmacologic Class) Phenothiazines
Thioridazine {u} (Compound) downregulates {v} (Gene) VAPB
Thioridazine {u} (Compound) causes {v} (Side Effect) Cholestasis
Thioridazine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium oxide
Thioridazine (Compound) resembles Prochlorperazine (Compound)
Thioridazine (Compound) resembles Ethopropazine (Compound)
Thioridazine may cause a moderate interaction that could exacerbate diseases when taken with Clemastine
Thioridazine (Compound) binds CYP2D6 (Gene)
Thioridazine (Compound) upregulates KDM5B (Gene)
Thioridazine (Compound) palliates schizophrenia (Disease)
Thioridazine (Compound) is included by Phenothiazines (Pharmacologic Class)
Thioridazine (Compound) downregulates VAPB (Gene)
Thioridazine (Compound) causes Cholestasis (Side Effect)
Thioridazine may cause a minor interaction that can limit clinical effects when taken with Magnesium oxide