DDInter1366 DDInter1652
Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.
Secukinumab is a fully human monoclonal IgG1/κ antibody against interleukin-17A (IL-17A), a proinflammatory cytokine implicated in various chronic immune-mediated inflammatory disorders, such as plaque psoriasis. By blocking the actions of IL-17A, secukinumab works to inhibit the pro-inflammatory pathways that drive immune-mediated inflammatory disorders. Following its first global approval in Japan in December 2014, secukinumab was approved by the European Commission on January 15, 2015, and by the FDA a few days after (January 21, 2015). It is currently approved to treat a number of chronic inflammatory conditions, such as plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, and hidradenitis suppurativa.[L39600,L42280,L48771]
Oxycodone {u} (Compound) resembles {v} (Compound) Hydromorphone
Oxycodone {u} (Compound) resembles {v} (Compound) Methylnaltrexone
Oxycodone {u} may lead to a major life threatening interaction when taken with {v} Naltrexone
Oxycodone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Naloxone
Oxycodone {u} (Compound) binds {v} (Gene) CYP3A4
Oxycodone {u} (Compound) is included by {v} (Pharmacologic Class) Full Opioid Agonists
Oxycodone {u} (Compound) causes {v} (Side Effect) Regurgitation
Oxycodone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Aldesleukin
Oxycodone {u} may lead to a major life threatening interaction when taken with {v} Chloramphenicol
Oxycodone (Compound) resembles Hydromorphone (Compound)
Oxycodone (Compound) resembles Methylnaltrexone (Compound)
Oxycodone may lead to a major life threatening interaction when taken with Naltrexone
Oxycodone may cause a moderate interaction that could exacerbate diseases when taken with Naloxone
Oxycodone (Compound) binds CYP3A4 (Gene)
Oxycodone (Compound) is included by Full Opioid Agonists (Pharmacologic Class)
Oxycodone (Compound) causes Regurgitation (Side Effect)
Oxycodone may cause a moderate interaction that could exacerbate diseases when taken with Aldesleukin
Oxycodone may lead to a major life threatening interaction when taken with Chloramphenicol