DDInter781 DDInter978
Fosinopril is a phosphinic acid-containing ester prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly hydrolyzed to fosinoprilat, its principle active metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Fosinopril may be used to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and microalbuminuria or overt nephropathy.
Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do not require dialysis. Due to less side effects than iron dextran, iron sucrose is more preferred in chronic kidney disease patients.
Fosinopril {u} (Compound) resembles {v} (Compound) Enalapril
Enalapril {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iron sucrose
Fosinopril {u} (Compound) resembles {v} (Compound) Enalapril
Enalapril {u} (Compound) resembles {v} (Compound) Moexipril
Moexipril {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iron sucrose
Fosinopril {u} (Compound) causes {v} (Side Effect) Urine output increased
Urine output increased {u} (Side Effect) is caused by {v} (Compound) Ergocalciferol
Ergocalciferol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iron sucrose
Fosinopril {u} (Compound) resembles {v} (Compound) Lisinopril
Lisinopril {u} (Compound) resembles {v} (Compound) Trandolapril
Trandolapril {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iron sucrose
Fosinopril {u} (Compound) resembles {v} (Compound) Spirapril
Spirapril {u} (Compound) resembles {v} (Compound) Moexipril
Moexipril {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iron sucrose
Fosinopril {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Moexipril
Moexipril {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iron sucrose
Fosinopril {u} (Compound) binds {v} (Gene) SLC15A2
SLC15A2 {u} (Gene) is bound by {v} (Compound) Moexipril
Moexipril {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iron sucrose
Fosinopril {u} (Compound) resembles {v} (Compound) Spirapril
Spirapril {u} (Compound) resembles {v} (Compound) Quinapril
Quinapril {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iron sucrose
Fosinopril {u} (Compound) causes {v} (Side Effect) Asthenia
Asthenia {u} (Side Effect) is caused by {v} (Compound) Dimercaprol
Dimercaprol {u} may lead to a major life threatening interaction when taken with {v} Iron sucrose
Fosinopril (Compound) resembles Enalapril (Compound) and Enalapril may cause a moderate interaction that could exacerbate diseases when taken with Iron sucrose
Fosinopril (Compound) resembles Enalapril (Compound) and Enalapril (Compound) resembles Moexipril (Compound) and Moexipril may cause a moderate interaction that could exacerbate diseases when taken with Iron sucrose
Fosinopril (Compound) causes Urine output increased (Side Effect) and Urine output increased (Side Effect) is caused by Ergocalciferol (Compound) and Ergocalciferol may cause a moderate interaction that could exacerbate diseases when taken with Iron sucrose
Fosinopril (Compound) resembles Lisinopril (Compound) and Lisinopril (Compound) resembles Trandolapril (Compound) and Trandolapril may cause a moderate interaction that could exacerbate diseases when taken with Iron sucrose
Fosinopril (Compound) resembles Spirapril (Compound) and Spirapril (Compound) resembles Moexipril (Compound) and Moexipril may cause a moderate interaction that could exacerbate diseases when taken with Iron sucrose
Fosinopril (Compound) treats hypertension (Disease) and hypertension (Disease) is treated by Moexipril (Compound) and Moexipril may cause a moderate interaction that could exacerbate diseases when taken with Iron sucrose
Fosinopril (Compound) binds SLC15A2 (Gene) and SLC15A2 (Gene) is bound by Moexipril (Compound) and Moexipril may cause a moderate interaction that could exacerbate diseases when taken with Iron sucrose
Fosinopril (Compound) resembles Spirapril (Compound) and Spirapril (Compound) resembles Quinapril (Compound) and Quinapril may cause a moderate interaction that could exacerbate diseases when taken with Iron sucrose
Fosinopril (Compound) causes Asthenia (Side Effect) and Asthenia (Side Effect) is caused by Dimercaprol (Compound) and Dimercaprol may lead to a major life threatening interaction when taken with Iron sucrose