DDInter336 DDInter1263
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in the colon. It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval in 1998. Interestingly, selective COX-2 inhibitors (especially celecoxib), have been evaluated as potential cancer chemopreventive and therapeutic drugs in clinical trials for a variety of malignancies.
Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Celecoxib {u} (Compound) causes {v} (Side Effect) Dyspnoea
Dyspnoea {u} (Side Effect) is caused by {v} (Compound) Naltrexone
Celecoxib {u} (Compound) causes {v} (Side Effect) Dyspnoea
Dyspnoea {u} (Side Effect) is caused by {v} (Compound) Oxycodone
Oxycodone {u} may lead to a major life threatening interaction when taken with {v} Naltrexone
Celecoxib {u} (Compound) causes {v} (Side Effect) Hypertension
Hypertension {u} (Side Effect) is caused by {v} (Compound) Butorphanol
Butorphanol {u} (Compound) resembles {v} (Compound) Naltrexone
Celecoxib {u} (Compound) causes {v} (Side Effect) Colitis
Colitis {u} (Side Effect) is caused by {v} (Compound) Fenofibrate
Fenofibrate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Naltrexone
Celecoxib {u} (Compound) causes {v} (Side Effect) Pancreatitis acute
Pancreatitis acute {u} (Side Effect) is caused by {v} (Compound) Valproic acid
Valproic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Naltrexone
Celecoxib {u} (Compound) causes {v} (Side Effect) Injection site reaction
Injection site reaction {u} (Side Effect) is caused by {v} (Compound) Buprenorphine
Buprenorphine {u} (Compound) resembles {v} (Compound) Naltrexone
Celecoxib {u} (Compound) resembles {v} (Compound) Sulfaphenazole
Sulfaphenazole {u} (Compound) resembles {v} (Compound) Sulfamethoxazole
Sulfamethoxazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Naltrexone
Celecoxib {u} (Compound) resembles {v} (Compound) Etoricoxib
Etoricoxib {u} (Compound) resembles {v} (Compound) Vemurafenib
Vemurafenib {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Naltrexone
Celecoxib {u} (Compound) binds {v} (Gene) CA14
CA14 {u} (Gene) is bound by {v} (Compound) Nilotinib
Nilotinib {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Naltrexone
Celecoxib {u} (Compound) resembles {v} (Compound) Etoricoxib
Etoricoxib {u} (Compound) causes {v} (Side Effect) Dyspnoea
Dyspnoea {u} (Side Effect) is caused by {v} (Compound) Naltrexone
Celecoxib (Compound) causes Dyspnoea (Side Effect) and Dyspnoea (Side Effect) is caused by Naltrexone (Compound)
Celecoxib (Compound) causes Dyspnoea (Side Effect) and Dyspnoea (Side Effect) is caused by Oxycodone (Compound) and Oxycodone may lead to a major life threatening interaction when taken with Naltrexone
Celecoxib (Compound) causes Hypertension (Side Effect) and Hypertension (Side Effect) is caused by Butorphanol (Compound) and Butorphanol (Compound) resembles Naltrexone (Compound)
Celecoxib (Compound) causes Colitis (Side Effect) and Colitis (Side Effect) is caused by Fenofibrate (Compound) and Fenofibrate may cause a moderate interaction that could exacerbate diseases when taken with Naltrexone
Celecoxib (Compound) causes Pancreatitis acute (Side Effect) and Pancreatitis acute (Side Effect) is caused by Valproic acid (Compound) and Valproic acid may cause a moderate interaction that could exacerbate diseases when taken with Naltrexone
Celecoxib (Compound) causes Injection site reaction (Side Effect) and Injection site reaction (Side Effect) is caused by Buprenorphine (Compound) and Buprenorphine (Compound) resembles Naltrexone (Compound)
Celecoxib (Compound) resembles Sulfaphenazole (Compound) and Sulfaphenazole (Compound) resembles Sulfamethoxazole (Compound) and Sulfamethoxazole may cause a moderate interaction that could exacerbate diseases when taken with Naltrexone
Celecoxib (Compound) resembles Etoricoxib (Compound) and Etoricoxib (Compound) resembles Vemurafenib (Compound) and Vemurafenib may cause a moderate interaction that could exacerbate diseases when taken with Naltrexone
Celecoxib (Compound) binds CA14 (Gene) and CA14 (Gene) is bound by Nilotinib (Compound) and Nilotinib may cause a moderate interaction that could exacerbate diseases when taken with Naltrexone
Celecoxib (Compound) resembles Etoricoxib (Compound) and Etoricoxib (Compound) causes Dyspnoea (Side Effect) and Dyspnoea (Side Effect) is caused by Naltrexone (Compound)