DDInter387 DDInter790
Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of water from the body. Furosemide has a fast onset and short duration of action and has been used safely and effectively in both pediatric and adult patients. The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential. In addition to oral formulations, the solution for intravenous and intramuscular administration is also available, which is typically limited to patients who are unable to take oral medication or for patients in emergency clinical situations.
Cisplatin {u} (Compound) binds {v} (Gene) ABCC2
ABCC2 {u} (Gene) is bound by {v} (Compound) Furosemide
Cisplatin {u} (Compound) causes {v} (Side Effect) Irritability
Irritability {u} (Side Effect) is caused by {v} (Compound) Furosemide
Cisplatin {u} (Compound) binds {v} (Gene) ABCC2
ABCC2 {u} (Gene) is associated with {v} (Disease) chronic kidney failure
chronic kidney failure {u} (Disease) is palliated by {v} (Compound) Furosemide
Cisplatin {u} (Compound) causes {v} (Side Effect) Irritability
Irritability {u} (Side Effect) is caused by {v} (Compound) Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Cisplatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Corticotropin
Corticotropin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Cisplatin {u} may lead to a major life threatening interaction when taken with {v} Ioversol
Ioversol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Cisplatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methotrexate
Methotrexate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Cisplatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pantoprazole
Pantoprazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Cisplatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methotrexate
Methotrexate {u} (Compound) binds {v} (Gene) SLC22A11
SLC22A11 {u} (Gene) is bound by {v} (Compound) Furosemide
Cisplatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pantoprazole
Pantoprazole {u} (Compound) causes {v} (Side Effect) Agitation
Agitation {u} (Side Effect) is caused by {v} (Compound) Furosemide
Cisplatin (Compound) binds ABCC2 (Gene) and ABCC2 (Gene) is bound by Furosemide (Compound)
Cisplatin (Compound) causes Irritability (Side Effect) and Irritability (Side Effect) is caused by Furosemide (Compound)
Cisplatin (Compound) binds ABCC2 (Gene) and ABCC2 (Gene) is associated with chronic kidney failure (Disease) and chronic kidney failure (Disease) is palliated by Furosemide (Compound)
Cisplatin (Compound) causes Irritability (Side Effect) and Irritability (Side Effect) is caused by Indapamide (Compound) and Indapamide (Compound) resembles Furosemide (Compound)
Cisplatin may cause a moderate interaction that could exacerbate diseases when taken with Corticotropin and Corticotropin may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) resembles Furosemide (Compound)
Cisplatin may lead to a major life threatening interaction when taken with Ioversol and Ioversol may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) resembles Furosemide (Compound)
Cisplatin may cause a moderate interaction that could exacerbate diseases when taken with Methotrexate and Methotrexate may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) resembles Furosemide (Compound)
Cisplatin may cause a moderate interaction that could exacerbate diseases when taken with Pantoprazole and Pantoprazole may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) resembles Furosemide (Compound)
Cisplatin may cause a moderate interaction that could exacerbate diseases when taken with Methotrexate and Methotrexate (Compound) binds SLC22A11 (Gene) and SLC22A11 (Gene) is bound by Furosemide (Compound)
Cisplatin may cause a moderate interaction that could exacerbate diseases when taken with Pantoprazole and Pantoprazole (Compound) causes Agitation (Side Effect) and Agitation (Side Effect) is caused by Furosemide (Compound)