DDInter1340 DDInter1887
Originally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class, and its approval was followed by the formulation of many other proton pump inhibitor drugs. Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults [FDA label].
Trovafloxacin is a broad spectrum antibiotic that has been commonly marketed under the brand name Trovan by Pfizer. It exerts its antibacterial activity by inhibiting the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV. It was shown to be more effective against Gram-positive bacteria than Gram-negative bacteria when compared to previous fluoroquinolones. Due to its hepatotoxic potential, trovafloxacin was withdrawn from the market.
Omeprazole {u} (Compound) causes {v} (Side Effect) Encephalopathy
Encephalopathy {u} (Side Effect) is caused by {v} (Compound) Trovafloxacin
Omeprazole {u} (Compound) causes {v} (Side Effect) Encephalopathy
Encephalopathy {u} (Side Effect) is caused by {v} (Compound) Carmustine
Carmustine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Trovafloxacin
Omeprazole {u} (Compound) causes {v} (Side Effect) Fatigue
Fatigue {u} (Side Effect) is caused by {v} (Compound) Gemifloxacin
Gemifloxacin {u} (Compound) resembles {v} (Compound) Trovafloxacin
Omeprazole {u} (Compound) causes {v} (Side Effect) Weight increased
Weight increased {u} (Side Effect) is caused by {v} (Compound) Hydroxyurea
Hydroxyurea {u} may cause a minor interaction that can limit clinical effects when taken with {v} Trovafloxacin
Omeprazole {u} (Compound) resembles {v} (Compound) Pantoprazole
Pantoprazole {u} (Compound) causes {v} (Side Effect) Agranulocytosis
Agranulocytosis {u} (Side Effect) is caused by {v} (Compound) Trovafloxacin
Omeprazole {u} (Compound) causes {v} (Side Effect) Arthropathy
Arthropathy {u} (Side Effect) is caused by {v} (Compound) Mycophenolic acid
Mycophenolic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Trovafloxacin
Omeprazole {u} (Compound) causes {v} (Side Effect) Tongue oedema
Tongue oedema {u} (Side Effect) is caused by {v} (Compound) Bupropion
Bupropion {u} may lead to a major life threatening interaction when taken with {v} Trovafloxacin
Omeprazole {u} (Compound) resembles {v} (Compound) Esomeprazole
Esomeprazole {u} (Compound) causes {v} (Side Effect) Muscle spasms
Muscle spasms {u} (Side Effect) is caused by {v} (Compound) Trovafloxacin
Omeprazole {u} (Compound) causes {v} (Side Effect) Arthropathy
Arthropathy {u} (Side Effect) is caused by {v} (Compound) Diclofenac
Diclofenac {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Trovafloxacin
Omeprazole {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Daunorubicin
Daunorubicin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Trovafloxacin
Omeprazole (Compound) causes Encephalopathy (Side Effect) and Encephalopathy (Side Effect) is caused by Trovafloxacin (Compound)
Omeprazole (Compound) causes Encephalopathy (Side Effect) and Encephalopathy (Side Effect) is caused by Carmustine (Compound) and Carmustine may cause a minor interaction that can limit clinical effects when taken with Trovafloxacin
Omeprazole (Compound) causes Fatigue (Side Effect) and Fatigue (Side Effect) is caused by Gemifloxacin (Compound) and Gemifloxacin (Compound) resembles Trovafloxacin (Compound)
Omeprazole (Compound) causes Weight increased (Side Effect) and Weight increased (Side Effect) is caused by Hydroxyurea (Compound) and Hydroxyurea may cause a minor interaction that can limit clinical effects when taken with Trovafloxacin
Omeprazole (Compound) resembles Pantoprazole (Compound) and Pantoprazole (Compound) causes Agranulocytosis (Side Effect) and Agranulocytosis (Side Effect) is caused by Trovafloxacin (Compound)
Omeprazole (Compound) causes Arthropathy (Side Effect) and Arthropathy (Side Effect) is caused by Mycophenolic acid (Compound) and Mycophenolic acid may cause a moderate interaction that could exacerbate diseases when taken with Trovafloxacin
Omeprazole (Compound) causes Tongue oedema (Side Effect) and Tongue oedema (Side Effect) is caused by Bupropion (Compound) and Bupropion may lead to a major life threatening interaction when taken with Trovafloxacin
Omeprazole (Compound) resembles Esomeprazole (Compound) and Esomeprazole (Compound) causes Muscle spasms (Side Effect) and Muscle spasms (Side Effect) is caused by Trovafloxacin (Compound)
Omeprazole (Compound) causes Arthropathy (Side Effect) and Arthropathy (Side Effect) is caused by Diclofenac (Compound) and Diclofenac may cause a moderate interaction that could exacerbate diseases when taken with Trovafloxacin
Omeprazole (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Daunorubicin (Compound) and Daunorubicin may cause a minor interaction that can limit clinical effects when taken with Trovafloxacin