DDInter11 DDInter1867
Acarbose is a complex oligosaccharide that acts as an inhibitor of several enzymes responsible for the breakdown of complex carbohydrates in the intestines. It inhibits both pancreatic alpha-amylase and membrane-bound alpha-glucosidases - including intestinal glucoamylase, sucrase, maltase, and isomaltase - which are responsible for the metabolism of complex starches and oligo-, tri-, and disaccharides into absorbable simple sugars.[L31633,A37868] By inhibiting the activity of these enzymes, acarbose limits the absorption of dietary carbohydrates and the subsequent postprandial increase in blood glucose and insulin levels. Acarbose is therefore used in conjunction with diet, exercise, and other pharmacotherapies for the management of blood sugar levels in patients with type 2 diabetes.[L31628,L31633] Acarbose is one of only two approved alpha-glucosidase inhibitors (the other being
A phenothiazine used as an antipsychotic agent and as an antiemetic.
Acarbose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Perphenazine
Perphenazine {u} (Compound) resembles {v} (Compound) Triflupromazine
Acarbose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Perphenazine
Perphenazine {u} (Compound) resembles {v} (Compound) Pipotiazine
Pipotiazine {u} (Compound) resembles {v} (Compound) Triflupromazine
Acarbose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Perphenazine
Perphenazine {u} (Compound) resembles {v} (Compound) Mequitazine
Mequitazine {u} (Compound) resembles {v} (Compound) Triflupromazine
Acarbose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methdilazine
Methdilazine {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Perphenazine
Perphenazine {u} (Compound) resembles {v} (Compound) Triflupromazine
Acarbose {u} (Compound) upregulates {v} (Gene) PAK1
PAK1 {u} (Gene) is upregulated by {v} (Compound) Ethopropazine
Ethopropazine {u} (Compound) resembles {v} (Compound) Triflupromazine
Acarbose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Benzphetamine
Benzphetamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methdilazine
Methdilazine {u} (Compound) resembles {v} (Compound) Triflupromazine
Acarbose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methdilazine
Methdilazine {u} (Compound) resembles {v} (Compound) Desipramine
Desipramine {u} (Compound) resembles {v} (Compound) Triflupromazine
Acarbose {u} (Compound) upregulates {v} (Gene) PAK1
PAK1 {u} (Gene) is upregulated by {v} (Compound) Prochlorperazine
Prochlorperazine {u} (Compound) resembles {v} (Compound) Triflupromazine
Acarbose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Perphenazine
Perphenazine {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methdilazine
Methdilazine {u} (Compound) resembles {v} (Compound) Triflupromazine
Acarbose {u} (Compound) binds {v} (Gene) GAA
GAA {u} (Gene) is upregulated by {v} (Compound) Perphenazine
Perphenazine {u} (Compound) resembles {v} (Compound) Triflupromazine
Acarbose may cause a moderate interaction that could exacerbate diseases when taken with Perphenazine and Perphenazine (Compound) resembles Triflupromazine (Compound)
Acarbose may cause a moderate interaction that could exacerbate diseases when taken with Perphenazine and Perphenazine (Compound) resembles Pipotiazine (Compound) and Pipotiazine (Compound) resembles Triflupromazine (Compound)
Acarbose may cause a moderate interaction that could exacerbate diseases when taken with Perphenazine and Perphenazine (Compound) resembles Mequitazine (Compound) and Mequitazine (Compound) resembles Triflupromazine (Compound)
Acarbose may cause a moderate interaction that could exacerbate diseases when taken with Methdilazine and Methdilazine (Compound) resembles Perphenazine (Compound) and Methdilazine may cause a moderate interaction that could exacerbate diseases when taken with Perphenazine and Perphenazine (Compound) resembles Triflupromazine (Compound)
Acarbose (Compound) upregulates PAK1 (Gene) and PAK1 (Gene) is upregulated by Ethopropazine (Compound) and Ethopropazine (Compound) resembles Triflupromazine (Compound)
Acarbose may cause a moderate interaction that could exacerbate diseases when taken with Benzphetamine and Benzphetamine may cause a moderate interaction that could exacerbate diseases when taken with Methdilazine and Methdilazine (Compound) resembles Triflupromazine (Compound)
Acarbose may cause a moderate interaction that could exacerbate diseases when taken with Methdilazine and Methdilazine (Compound) resembles Desipramine (Compound) and Desipramine (Compound) resembles Triflupromazine (Compound)
Acarbose (Compound) upregulates PAK1 (Gene) and PAK1 (Gene) is upregulated by Prochlorperazine (Compound) and Prochlorperazine (Compound) resembles Triflupromazine (Compound)
Acarbose may cause a moderate interaction that could exacerbate diseases when taken with Perphenazine and Perphenazine (Compound) resembles Methdilazine (Compound) and Perphenazine may cause a moderate interaction that could exacerbate diseases when taken with Methdilazine and Methdilazine (Compound) resembles Triflupromazine (Compound)
Acarbose (Compound) binds GAA (Gene) and GAA (Gene) is upregulated by Perphenazine (Compound) and Perphenazine (Compound) resembles Triflupromazine (Compound)