DDInter172 DDInter1966
Belatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1). Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each. It is produced through recombinant DNA technology in mammalian CHO cells. The drug has activity as a selective co-stimulation modulator with inhibitory activity on T lymphocytes. It is approved for the treatment of rheumatoid arthritis. Belatacept selectively blocks the process of T-cell activation. It was developed by Bristol-Myers-Squibb. Belatacept is only 2 amino acids different
Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol". It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Zinc sulfate {u} may cause a minor interaction that can limit clinical effects when taken with {v} Efalizumab
Zinc sulfate {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ixekizumab
Zinc sulfate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Trovafloxacin
Zinc sulfate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Baloxavir marboxil
Zinc sulfate {u} may lead to a major life threatening interaction when taken with {v} Raltegravir
Zinc sulfate may cause a minor interaction that can limit clinical effects when taken with Efalizumab
Zinc sulfate may cause a minor interaction that can limit clinical effects when taken with Ixekizumab
Zinc sulfate may cause a moderate interaction that could exacerbate diseases when taken with Trovafloxacin
Zinc sulfate may cause a moderate interaction that could exacerbate diseases when taken with Baloxavir marboxil
Zinc sulfate may lead to a major life threatening interaction when taken with Raltegravir