DDInter577 DDInter1376
A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26, 2020.[L12573,L12582] The US approval was followed by the approval in Canada on October 2, 2020. In November 2021, ozanimod was also approved by the European Commission for the treatment of adults with relapsing remitting multiple sclerosis.[L39377,L39382] MS is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Inflammatory bowel disease also a chronic inflammatory condition and can cause persistent abdominal pain, diarrhea, bloody stools, and vomiting. In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard in MS therapy. Studies involving patients with inflammatory bowel disease have also shown promising results.[A189318,A189342]
Dobutamine {u} (Compound) resembles {v} (Compound) Masoprocol
Dobutamine {u} (Compound) resembles {v} (Compound) Dopamine
Dobutamine {u} (Compound) binds {v} (Gene) ADRB2
Dobutamine {u} (Compound) downregulates {v} (Gene) DNAJA3
Dobutamine {u} (Compound) causes {v} (Side Effect) Thrombocytopenia
Dobutamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Desmopressin
Dobutamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Exenatide
Dobutamine {u} may lead to a major life threatening interaction when taken with {v} Cocaine
Dobutamine {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Formoterol
Dobutamine (Compound) resembles Masoprocol (Compound)
Dobutamine (Compound) resembles Dopamine (Compound)
Dobutamine (Compound) binds ADRB2 (Gene)
Dobutamine (Compound) downregulates DNAJA3 (Gene)
Dobutamine (Compound) causes Thrombocytopenia (Side Effect)
Dobutamine may cause a moderate interaction that could exacerbate diseases when taken with Desmopressin
Dobutamine may cause a moderate interaction that could exacerbate diseases when taken with Exenatide
Dobutamine may lead to a major life threatening interaction when taken with Cocaine
Dobutamine (Compound) resembles Formoterol (Compound) and Dobutamine may cause a moderate interaction that could exacerbate diseases when taken with Formoterol