DDInter668 DDInter1252
Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to treat various bacterial infections.
Mycophenolic acid is a potent immunosuppressant agent that inhibits _de novo_ purine biosynthesis. It was derived from _Penicillium stoloniferum_, and has also shown antibacterial, antifungal and antiviral properties.. Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. This regimen can be used in place of the older anti-proliferative [azathioprine] due to its stronger immunosuppressive potency. However, mycophenolic acid treatment is more expensive and requires therapeutic drug monitoring to optimize efficacy and minimize toxicity.[A249180,A249185] Mycophenolic acid is available as enteric-coated tablets of delayed-release, in an effort to improve upper gastrointestinal adverse events by delaying mycophenolic acid release until it reaches the small intestine. [Mycophenolate mofetil], a prodrug of mycophenolic acid, is also prescribed to transplant recipients to prevent organ rejection.
Ertapenem {u} (Compound) causes {v} (Side Effect) Nervous system disorder
Nervous system disorder {u} (Side Effect) is caused by {v} (Compound) Mycophenolic acid
Ertapenem {u} (Compound) resembles {v} (Compound) Meropenem
Meropenem {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mycophenolic acid
Ertapenem {u} (Compound) causes {v} (Side Effect) Nervous system disorder
Nervous system disorder {u} (Side Effect) is caused by {v} (Compound) Mycophenolate mofetil
Mycophenolate mofetil {u} (Compound) resembles {v} (Compound) Mycophenolic acid
Ertapenem {u} (Compound) causes {v} (Side Effect) Loose stools
Loose stools {u} (Side Effect) is caused by {v} (Compound) Ceftriaxone
Ceftriaxone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mycophenolic acid
Ertapenem {u} (Compound) causes {v} (Side Effect) Wheezing
Wheezing {u} (Side Effect) is caused by {v} (Compound) Iron
Iron {u} may cause a minor interaction that can limit clinical effects when taken with {v} Mycophenolic acid
Ertapenem {u} (Compound) causes {v} (Side Effect) Abdominal pain upper
Abdominal pain upper {u} (Side Effect) is caused by {v} (Compound) Theophylline
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Mycophenolic acid
Ertapenem {u} (Compound) causes {v} (Side Effect) Wound infection
Wound infection {u} (Side Effect) is caused by {v} (Compound) Sirolimus
Sirolimus {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mycophenolic acid
Ertapenem {u} (Compound) resembles {v} (Compound) Meropenem
Meropenem {u} (Compound) causes {v} (Side Effect) Nervous system disorder
Nervous system disorder {u} (Side Effect) is caused by {v} (Compound) Mycophenolic acid
Ertapenem {u} (Compound) causes {v} (Side Effect) Gastric ulcer
Gastric ulcer {u} (Side Effect) is caused by {v} (Compound) Deferiprone
Deferiprone {u} may lead to a major life threatening interaction when taken with {v} Mycophenolic acid
Ertapenem {u} (Compound) causes {v} (Side Effect) Blood pressure increased
Blood pressure increased {u} (Side Effect) is caused by {v} (Compound) Etonogestrel
Etonogestrel {u} may lead to a major life threatening interaction when taken with {v} Mycophenolic acid
Ertapenem (Compound) causes Nervous system disorder (Side Effect) and Nervous system disorder (Side Effect) is caused by Mycophenolic acid (Compound)
Ertapenem (Compound) resembles Meropenem (Compound) and Meropenem may cause a moderate interaction that could exacerbate diseases when taken with Mycophenolic acid
Ertapenem (Compound) causes Nervous system disorder (Side Effect) and Nervous system disorder (Side Effect) is caused by Mycophenolate mofetil (Compound) and Mycophenolate mofetil (Compound) resembles Mycophenolic acid (Compound)
Ertapenem (Compound) causes Loose stools (Side Effect) and Loose stools (Side Effect) is caused by Ceftriaxone (Compound) and Ceftriaxone may cause a moderate interaction that could exacerbate diseases when taken with Mycophenolic acid
Ertapenem (Compound) causes Wheezing (Side Effect) and Wheezing (Side Effect) is caused by Iron (Compound) and Iron may cause a minor interaction that can limit clinical effects when taken with Mycophenolic acid
Ertapenem (Compound) causes Abdominal pain upper (Side Effect) and Abdominal pain upper (Side Effect) is caused by Theophylline (Compound) and Theophylline may cause a minor interaction that can limit clinical effects when taken with Mycophenolic acid
Ertapenem (Compound) causes Wound infection (Side Effect) and Wound infection (Side Effect) is caused by Sirolimus (Compound) and Sirolimus may cause a moderate interaction that could exacerbate diseases when taken with Mycophenolic acid
Ertapenem (Compound) resembles Meropenem (Compound) and Meropenem (Compound) causes Nervous system disorder (Side Effect) and Nervous system disorder (Side Effect) is caused by Mycophenolic acid (Compound)
Ertapenem (Compound) causes Gastric ulcer (Side Effect) and Gastric ulcer (Side Effect) is caused by Deferiprone (Compound) and Deferiprone may lead to a major life threatening interaction when taken with Mycophenolic acid
Ertapenem (Compound) causes Blood pressure increased (Side Effect) and Blood pressure increased (Side Effect) is caused by Etonogestrel (Compound) and Etonogestrel may lead to a major life threatening interaction when taken with Mycophenolic acid