DDInter1818 DDInter1662
Tirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation.
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before beneficial effects are noticed. Sertraline displays enhanced safety or tolerability than other classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and other undesirable effects.[A1846,A187075,T28]
Tirofiban {u} (Compound) causes {v} (Side Effect) Anaphylactic shock
Anaphylactic shock {u} (Side Effect) is caused by {v} (Compound) Sertraline
Tirofiban {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Maprotiline
Maprotiline {u} (Compound) resembles {v} (Compound) Sertraline
Tirofiban {u} (Compound) treats {v} (Disease) coronary artery disease
coronary artery disease {u} (Disease) is associated with {v} (Gene) BIRC5
BIRC5 {u} (Gene) is downregulated by {v} (Compound) Sertraline
Tirofiban {u} (Compound) binds {v} (Gene) ITGB3
ITGB3 {u} (Gene) is associated with {v} (Disease) autistic disorder
autistic disorder {u} (Disease) is palliated by {v} (Compound) Sertraline
Tirofiban {u} (Compound) treats {v} (Disease) coronary artery disease
coronary artery disease {u} (Disease) is associated with {v} (Gene) CYP2C19
CYP2C19 {u} (Gene) is bound by {v} (Compound) Sertraline
Tirofiban {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Meclofenamic acid
Meclofenamic acid {u} (Compound) downregulates {v} (Gene) CSRP1
CSRP1 {u} (Gene) is downregulated by {v} (Compound) Sertraline
Tirofiban {u} (Compound) binds {v} (Gene) ITGB3
ITGB3 {u} (Gene) regulates {v} (Gene) GNPDA1
GNPDA1 {u} (Gene) is upregulated by {v} (Compound) Sertraline
Tirofiban {u} (Compound) treats {v} (Disease) coronary artery disease
coronary artery disease {u} (Disease) is associated with {v} (Gene) LDLR
LDLR {u} (Gene) is upregulated by {v} (Compound) Sertraline
Tirofiban {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Icosapent
Icosapent {u} (Compound) causes {v} (Side Effect) Dyspepsia
Dyspepsia {u} (Side Effect) is caused by {v} (Compound) Sertraline
Tirofiban {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Meclofenamic acid
Meclofenamic acid {u} (Compound) causes {v} (Side Effect) Feeling abnormal
Feeling abnormal {u} (Side Effect) is caused by {v} (Compound) Sertraline
Tirofiban (Compound) causes Anaphylactic shock (Side Effect) and Anaphylactic shock (Side Effect) is caused by Sertraline (Compound)
Tirofiban (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Maprotiline (Compound) and Maprotiline (Compound) resembles Sertraline (Compound)
Tirofiban (Compound) treats coronary artery disease (Disease) and coronary artery disease (Disease) is associated with BIRC5 (Gene) and BIRC5 (Gene) is downregulated by Sertraline (Compound)
Tirofiban (Compound) binds ITGB3 (Gene) and ITGB3 (Gene) is associated with autistic disorder (Disease) and autistic disorder (Disease) is palliated by Sertraline (Compound)
Tirofiban (Compound) treats coronary artery disease (Disease) and coronary artery disease (Disease) is associated with CYP2C19 (Gene) and CYP2C19 (Gene) is bound by Sertraline (Compound)
Tirofiban may cause a moderate interaction that could exacerbate diseases when taken with Meclofenamic acid and Meclofenamic acid (Compound) downregulates CSRP1 (Gene) and CSRP1 (Gene) is downregulated by Sertraline (Compound)
Tirofiban (Compound) binds ITGB3 (Gene) and ITGB3 (Gene) regulates GNPDA1 (Gene) and GNPDA1 (Gene) is upregulated by Sertraline (Compound)
Tirofiban (Compound) treats coronary artery disease (Disease) and coronary artery disease (Disease) is associated with LDLR (Gene) and LDLR (Gene) is upregulated by Sertraline (Compound)
Tirofiban may cause a moderate interaction that could exacerbate diseases when taken with Icosapent and Icosapent (Compound) causes Dyspepsia (Side Effect) and Dyspepsia (Side Effect) is caused by Sertraline (Compound)
Tirofiban may cause a moderate interaction that could exacerbate diseases when taken with Meclofenamic acid and Meclofenamic acid (Compound) causes Feeling abnormal (Side Effect) and Feeling abnormal (Side Effect) is caused by Sertraline (Compound)