DDInter1627 DDInter1427
Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. Clinical trials suggest its efficacy in the treatment of partial seizures.
Pentoxyverine, also referred to as carbetapentane, is a non-opioid central acting antitussive with antimuscarinic, anticonvulsant , and local anesthetic properties. It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and H1-receptor antagonists . Pentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. The FDA withdrew the use of all oral gel drug products containing pentoxyverine citrate. Other forms of pentoxyverine citrate continue to be marketed.
Rufinamide {u} (Compound) treats {v} (Disease) epilepsy syndrome
epilepsy syndrome {u} (Disease) is treated by {v} (Compound) Levetiracetam
Levetiracetam {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pentoxyverine
Rufinamide {u} (Compound) binds {v} (Gene) SCN7A
SCN7A {u} (Gene) is bound by {v} (Compound) Ethotoin
Ethotoin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pentoxyverine
Rufinamide {u} (Compound) causes {v} (Side Effect) Mental disorder
Mental disorder {u} (Side Effect) is caused by {v} (Compound) Tapentadol
Tapentadol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pentoxyverine
Rufinamide {u} (Compound) causes {v} (Side Effect) Thrombocytopenia
Thrombocytopenia {u} (Side Effect) is caused by {v} (Compound) Selegiline
Selegiline {u} may lead to a major life threatening interaction when taken with {v} Pentoxyverine
Rufinamide {u} (Compound) binds {v} (Gene) CYP2E1
CYP2E1 {u} (Gene) is bound by {v} (Compound) Phenelzine
Phenelzine {u} may lead to a major life threatening interaction when taken with {v} Pentoxyverine
Rufinamide (Compound) treats epilepsy syndrome (Disease) and epilepsy syndrome (Disease) is treated by Levetiracetam (Compound) and Levetiracetam may cause a moderate interaction that could exacerbate diseases when taken with Pentoxyverine
Rufinamide (Compound) binds SCN7A (Gene) and SCN7A (Gene) is bound by Ethotoin (Compound) and Ethotoin may cause a moderate interaction that could exacerbate diseases when taken with Pentoxyverine
Rufinamide (Compound) causes Mental disorder (Side Effect) and Mental disorder (Side Effect) is caused by Tapentadol (Compound) and Tapentadol may cause a moderate interaction that could exacerbate diseases when taken with Pentoxyverine
Rufinamide (Compound) causes Thrombocytopenia (Side Effect) and Thrombocytopenia (Side Effect) is caused by Selegiline (Compound) and Selegiline may lead to a major life threatening interaction when taken with Pentoxyverine
Rufinamide (Compound) binds CYP2E1 (Gene) and CYP2E1 (Gene) is bound by Phenelzine (Compound) and Phenelzine may lead to a major life threatening interaction when taken with Pentoxyverine