DDInter70 DDInter1853
An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin A] (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant, and free radical-scavenging activities. It has been used in dermatology for many years to treat various skin conditions ranging from acne to wrinkles [A257474,A258185] and activates nuclear receptors to regulate epithelial cell growth and differentiation.[A257474,A257629,A257609] Tretinoin is given orally to treat acute promyelocytic leukemia and topically to treat skin conditions such as acne.[L45389,L34869,L45384]
Aminocaproic acid {u} (Compound) upregulates {v} (Gene) MAL
MAL {u} (Gene) is upregulated by {v} (Compound) Tretinoin
Aminocaproic acid {u} (Compound) downregulates {v} (Gene) ENOPH1
ENOPH1 {u} (Gene) is downregulated by {v} (Compound) Tretinoin
Aminocaproic acid {u} (Compound) upregulates {v} (Gene) CEBPA
CEBPA {u} (Gene) is downregulated by {v} (Compound) Tretinoin
Aminocaproic acid {u} (Compound) causes {v} (Side Effect) Agranulocytosis
Agranulocytosis {u} (Side Effect) is caused by {v} (Compound) Tretinoin
Aminocaproic acid {u} (Compound) upregulates {v} (Gene) MAL
MAL {u} (Gene) is upregulated by {v} (Compound) Isotretinoin
Isotretinoin {u} (Compound) resembles {v} (Compound) Tretinoin
Aminocaproic acid {u} (Compound) downregulates {v} (Gene) ENOPH1
ENOPH1 {u} (Gene) is downregulated by {v} (Compound) Isotretinoin
Isotretinoin {u} (Compound) resembles {v} (Compound) Tretinoin
Aminocaproic acid {u} (Compound) upregulates {v} (Gene) CEBPA
CEBPA {u} (Gene) is downregulated by {v} (Compound) Isotretinoin
Isotretinoin {u} (Compound) resembles {v} (Compound) Tretinoin
Aminocaproic acid {u} (Compound) causes {v} (Side Effect) Agranulocytosis
Agranulocytosis {u} (Side Effect) is caused by {v} (Compound) Isotretinoin
Isotretinoin {u} (Compound) resembles {v} (Compound) Tretinoin
Aminocaproic acid {u} (Compound) resembles {v} (Compound) Glycine
Glycine {u} (Compound) binds {v} (Gene) ALAS1
ALAS1 {u} (Gene) is upregulated by {v} (Compound) Tretinoin
Aminocaproic acid {u} (Compound) resembles {v} (Compound) Aminolevulinic acid
Aminolevulinic acid {u} (Compound) upregulates {v} (Gene) POLD4
POLD4 {u} (Gene) is upregulated by {v} (Compound) Tretinoin
Aminocaproic acid (Compound) upregulates MAL (Gene) and MAL (Gene) is upregulated by Tretinoin (Compound)
Aminocaproic acid (Compound) downregulates ENOPH1 (Gene) and ENOPH1 (Gene) is downregulated by Tretinoin (Compound)
Aminocaproic acid (Compound) upregulates CEBPA (Gene) and CEBPA (Gene) is downregulated by Tretinoin (Compound)
Aminocaproic acid (Compound) causes Agranulocytosis (Side Effect) and Agranulocytosis (Side Effect) is caused by Tretinoin (Compound)
Aminocaproic acid (Compound) upregulates MAL (Gene) and MAL (Gene) is upregulated by Isotretinoin (Compound) and Isotretinoin (Compound) resembles Tretinoin (Compound)
Aminocaproic acid (Compound) downregulates ENOPH1 (Gene) and ENOPH1 (Gene) is downregulated by Isotretinoin (Compound) and Isotretinoin (Compound) resembles Tretinoin (Compound)
Aminocaproic acid (Compound) upregulates CEBPA (Gene) and CEBPA (Gene) is downregulated by Isotretinoin (Compound) and Isotretinoin (Compound) resembles Tretinoin (Compound)
Aminocaproic acid (Compound) causes Agranulocytosis (Side Effect) and Agranulocytosis (Side Effect) is caused by Isotretinoin (Compound) and Isotretinoin (Compound) resembles Tretinoin (Compound)
Aminocaproic acid (Compound) resembles Glycine (Compound) and Glycine (Compound) binds ALAS1 (Gene) and ALAS1 (Gene) is upregulated by Tretinoin (Compound)
Aminocaproic acid (Compound) resembles Aminolevulinic acid (Compound) and Aminolevulinic acid (Compound) upregulates POLD4 (Gene) and POLD4 (Gene) is upregulated by Tretinoin (Compound)