DDInter1158 DDInter85
An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease. Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical agent. Throughout the late seventies and the eighties, important research initiatives developed stable mesalazine formulations like the eudragit-S coating of Asacol brand mesalazine and the Pentasa brand's encapsulation of mesalazine within microgranules. In the present day, contemporary research regarding novel methods to stabilize mesalazine continues and interest in the agent's capacity to decrease inflammatory activity and subsequently potentially reduce the risk of colorectal cancer in conditions like ulcerative colitis is maintained.[A174019,A174022]
Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.
Mesalazine {u} (Compound) causes {v} (Side Effect) Bronchospasm
Bronchospasm {u} (Side Effect) is caused by {v} (Compound) Amphotericin B
Mesalazine {u} (Compound) resembles {v} (Compound) Olsalazine
Olsalazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amphotericin B
Mesalazine {u} (Compound) causes {v} (Side Effect) Bronchospasm
Bronchospasm {u} (Side Effect) is caused by {v} (Compound) Cyclophosphamide
Cyclophosphamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amphotericin B
Mesalazine {u} (Compound) causes {v} (Side Effect) Coma
Coma {u} (Side Effect) is caused by {v} (Compound) Voriconazole
Voriconazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Amphotericin B
Mesalazine {u} (Compound) causes {v} (Side Effect) Paraesthesia
Paraesthesia {u} (Side Effect) is caused by {v} (Compound) Natamycin
Natamycin {u} (Compound) resembles {v} (Compound) Amphotericin B
Mesalazine {u} (Compound) causes {v} (Side Effect) Musculoskeletal pain
Musculoskeletal pain {u} (Side Effect) is caused by {v} (Compound) Hydrochlorothiazide
Hydrochlorothiazide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amphotericin B
Mesalazine {u} (Compound) causes {v} (Side Effect) Abdominal pain upper
Abdominal pain upper {u} (Side Effect) is caused by {v} (Compound) Miconazole
Miconazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Amphotericin B
Mesalazine {u} (Compound) resembles {v} (Compound) Carbidopa
Carbidopa {u} (Compound) causes {v} (Side Effect) Vascular purpura
Vascular purpura {u} (Side Effect) is caused by {v} (Compound) Amphotericin B
Mesalazine {u} (Compound) resembles {v} (Compound) Olsalazine
Olsalazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methotrexate
Methotrexate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amphotericin B
Mesalazine {u} (Compound) causes {v} (Side Effect) Rash pustular
Rash pustular {u} (Side Effect) is caused by {v} (Compound) Foscarnet
Foscarnet {u} may lead to a major life threatening interaction when taken with {v} Amphotericin B
Mesalazine (Compound) causes Bronchospasm (Side Effect) and Bronchospasm (Side Effect) is caused by Amphotericin B (Compound)
Mesalazine (Compound) resembles Olsalazine (Compound) and Olsalazine may cause a moderate interaction that could exacerbate diseases when taken with Amphotericin B
Mesalazine (Compound) causes Bronchospasm (Side Effect) and Bronchospasm (Side Effect) is caused by Cyclophosphamide (Compound) and Cyclophosphamide may cause a moderate interaction that could exacerbate diseases when taken with Amphotericin B
Mesalazine (Compound) causes Coma (Side Effect) and Coma (Side Effect) is caused by Voriconazole (Compound) and Voriconazole may cause a minor interaction that can limit clinical effects when taken with Amphotericin B
Mesalazine (Compound) causes Paraesthesia (Side Effect) and Paraesthesia (Side Effect) is caused by Natamycin (Compound) and Natamycin (Compound) resembles Amphotericin B (Compound)
Mesalazine (Compound) causes Musculoskeletal pain (Side Effect) and Musculoskeletal pain (Side Effect) is caused by Hydrochlorothiazide (Compound) and Hydrochlorothiazide may cause a moderate interaction that could exacerbate diseases when taken with Amphotericin B
Mesalazine (Compound) causes Abdominal pain upper (Side Effect) and Abdominal pain upper (Side Effect) is caused by Miconazole (Compound) and Miconazole may cause a minor interaction that can limit clinical effects when taken with Amphotericin B
Mesalazine (Compound) resembles Carbidopa (Compound) and Carbidopa (Compound) causes Vascular purpura (Side Effect) and Vascular purpura (Side Effect) is caused by Amphotericin B (Compound)
Mesalazine (Compound) resembles Olsalazine (Compound) and Olsalazine may cause a moderate interaction that could exacerbate diseases when taken with Methotrexate and Methotrexate may cause a moderate interaction that could exacerbate diseases when taken with Amphotericin B
Mesalazine (Compound) causes Rash pustular (Side Effect) and Rash pustular (Side Effect) is caused by Foscarnet (Compound) and Foscarnet may lead to a major life threatening interaction when taken with Amphotericin B