DDInter856 DDInter657
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated hepar
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension.
Epoprostenol {u} (Compound) resembles {v} (Compound) Dinoprost Tromethamine
Epoprostenol {u} (Compound) resembles {v} (Compound) Treprostinil
Epoprostenol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Alprostadil
Epoprostenol {u} (Compound) binds {v} (Gene) P2RY12
Epoprostenol {u} (Compound) palliates {v} (Disease) systemic scleroderma
Epoprostenol {u} (Compound) is included by {v} (Pharmacologic Class) Vasodilation
Epoprostenol {u} (Compound) causes {v} (Side Effect) Hypoaesthesia
Epoprostenol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Capsicum
Epoprostenol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Digoxin
Epoprostenol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Plicamycin
Epoprostenol (Compound) resembles Dinoprost Tromethamine (Compound)
Epoprostenol (Compound) resembles Treprostinil (Compound)
Epoprostenol may cause a moderate interaction that could exacerbate diseases when taken with Alprostadil
Epoprostenol (Compound) binds P2RY12 (Gene)
Epoprostenol (Compound) palliates systemic scleroderma (Disease)
Epoprostenol (Compound) is included by Vasodilation (Pharmacologic Class)
Epoprostenol (Compound) causes Hypoaesthesia (Side Effect)
Epoprostenol may cause a minor interaction that can limit clinical effects when taken with Capsicum
Epoprostenol may cause a minor interaction that can limit clinical effects when taken with Digoxin
Epoprostenol may cause a moderate interaction that could exacerbate diseases when taken with Plicamycin