DDInter1822 DDInter20
Aminoglycosides, many of which are derived directly from _Streptomyces_ spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic _Pseudomonas aeruginosa_ infections in cystic fibrosis patients, as _P. aeruginosa_ is notoriously inherently resistant to many antibiotics.[A232294, A232299, L32739] However, tobramycin can also be administered intravenously and topically to treat a variety of infections caused by susceptible bacteria.[L32744, L32749] Its use is limited in some cases by characteristic toxicities such as nephrotoxicity and ototoxicity, yet it remains a valuable option in the face of growing resistance to front-line antibiotics such as β-lactams and cephalosporins.[A232294, A232349, L
Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) [FDA label]. Interestingly, the results of various studies have demonstrated that long-term use of acetylsalicylic acid may decrease the risk of various cancers, including colorectal, esophageal, breast, lung, prostate, liver and skin cancer . Aspirin is classified as a _non-selective cyclooxygenase (COX) inhibitor_ [A32682, A177268] and is available in many doses and forms, including chewable tablets, suppositories, extended release formulations, and others . Acetylsalicylic acid is a very common cause of accidental poisoning in young children. It should be kept out of reach from young children, toddlers, and infants [FDA label].
Tobramycin {u} (Compound) causes {v} (Side Effect) Chest discomfort
Chest discomfort {u} (Side Effect) is caused by {v} (Compound) Acetylsalicylic acid
Tobramycin {u} (Compound) resembles {v} (Compound) Gentamicin
Gentamicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acetylsalicylic acid
Tobramycin {u} (Compound) resembles {v} (Compound) Kanamycin
Kanamycin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acetylsalicylic acid
Tobramycin {u} (Compound) causes {v} (Side Effect) Chest discomfort
Chest discomfort {u} (Side Effect) is caused by {v} (Compound) Nitroglycerin
Nitroglycerin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Acetylsalicylic acid
Tobramycin {u} (Compound) causes {v} (Side Effect) Asthma
Asthma {u} (Side Effect) is caused by {v} (Compound) Salicylic acid
Salicylic acid {u} (Compound) resembles {v} (Compound) Acetylsalicylic acid
Tobramycin {u} (Compound) resembles {v} (Compound) Gentamicin
Gentamicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Meclofenamic acid
Meclofenamic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acetylsalicylic acid
Tobramycin {u} (Compound) resembles {v} (Compound) Paromomycin
Paromomycin {u} (Compound) resembles {v} (Compound) Kanamycin
Kanamycin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acetylsalicylic acid
Tobramycin {u} (Compound) resembles {v} (Compound) Kanamycin
Kanamycin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Meclofenamic acid
Meclofenamic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acetylsalicylic acid
Tobramycin {u} (Compound) causes {v} (Side Effect) Leukopenia
Leukopenia {u} (Side Effect) is caused by {v} (Compound) Meclofenamic acid
Meclofenamic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acetylsalicylic acid
Tobramycin {u} (Compound) causes {v} (Side Effect) Hypokalaemia
Hypokalaemia {u} (Side Effect) is caused by {v} (Compound) Fosphenytoin
Fosphenytoin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Acetylsalicylic acid
Tobramycin (Compound) causes Chest discomfort (Side Effect) and Chest discomfort (Side Effect) is caused by Acetylsalicylic acid (Compound)
Tobramycin (Compound) resembles Gentamicin (Compound) and Gentamicin may cause a moderate interaction that could exacerbate diseases when taken with Acetylsalicylic acid
Tobramycin (Compound) resembles Kanamycin (Compound) and Kanamycin may cause a moderate interaction that could exacerbate diseases when taken with Acetylsalicylic acid
Tobramycin (Compound) causes Chest discomfort (Side Effect) and Chest discomfort (Side Effect) is caused by Nitroglycerin (Compound) and Nitroglycerin may cause a minor interaction that can limit clinical effects when taken with Acetylsalicylic acid
Tobramycin (Compound) causes Asthma (Side Effect) and Asthma (Side Effect) is caused by Salicylic acid (Compound) and Salicylic acid (Compound) resembles Acetylsalicylic acid (Compound)
Tobramycin (Compound) resembles Gentamicin (Compound) and Gentamicin may cause a moderate interaction that could exacerbate diseases when taken with Meclofenamic acid and Meclofenamic acid may cause a moderate interaction that could exacerbate diseases when taken with Acetylsalicylic acid
Tobramycin (Compound) resembles Paromomycin (Compound) and Paromomycin (Compound) resembles Kanamycin (Compound) and Kanamycin may cause a moderate interaction that could exacerbate diseases when taken with Acetylsalicylic acid
Tobramycin (Compound) resembles Kanamycin (Compound) and Kanamycin may cause a moderate interaction that could exacerbate diseases when taken with Meclofenamic acid and Meclofenamic acid may cause a moderate interaction that could exacerbate diseases when taken with Acetylsalicylic acid
Tobramycin (Compound) causes Leukopenia (Side Effect) and Leukopenia (Side Effect) is caused by Meclofenamic acid (Compound) and Meclofenamic acid may cause a moderate interaction that could exacerbate diseases when taken with Acetylsalicylic acid
Tobramycin (Compound) causes Hypokalaemia (Side Effect) and Hypokalaemia (Side Effect) is caused by Fosphenytoin (Compound) and Fosphenytoin may cause a minor interaction that can limit clinical effects when taken with Acetylsalicylic acid