DDInter179 DDInter336
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in the colon. It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval in 1998. Interestingly, selective COX-2 inhibitors (especially celecoxib), have been evaluated as potential cancer chemopreventive and therapeutic drugs in clinical trials for a variety of malignancies.
Bendroflumethiazide {u} (Compound) binds {v} (Gene) CA4
CA4 {u} (Gene) is bound by {v} (Compound) Celecoxib
Bendroflumethiazide {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Celecoxib
Bendroflumethiazide {u} (Compound) binds {v} (Gene) CA4
CA4 {u} (Gene) is downregulated by {v} (Disease) kidney cancer
kidney cancer {u} (Disease) is palliated by {v} (Compound) Celecoxib
Bendroflumethiazide {u} (Compound) binds {v} (Gene) CA2
CA2 {u} (Gene) is associated with {v} (Disease) kidney cancer
kidney cancer {u} (Disease) is palliated by {v} (Compound) Celecoxib
Bendroflumethiazide {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Etoricoxib
Etoricoxib {u} (Compound) resembles {v} (Compound) Celecoxib
Bendroflumethiazide {u} (Compound) resembles {v} (Compound) Benzthiazide
Benzthiazide {u} (Compound) binds {v} (Gene) CA9
CA9 {u} (Gene) is bound by {v} (Compound) Celecoxib
Bendroflumethiazide {u} (Compound) binds {v} (Gene) CA2
CA2 {u} (Gene) regulates {v} (Gene) RBM34
RBM34 {u} (Gene) is downregulated by {v} (Compound) Celecoxib
Bendroflumethiazide {u} (Compound) resembles {v} (Compound) Cyclothiazide
Cyclothiazide {u} (Compound) binds {v} (Gene) CA2
CA2 {u} (Gene) is bound by {v} (Compound) Celecoxib
Bendroflumethiazide {u} (Compound) resembles {v} (Compound) Polythiazide
Polythiazide {u} (Compound) causes {v} (Side Effect) Hyperglycaemia
Hyperglycaemia {u} (Side Effect) is caused by {v} (Compound) Celecoxib
Bendroflumethiazide {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is associated with {v} (Gene) PTGS2
PTGS2 {u} (Gene) is bound by {v} (Compound) Celecoxib
Bendroflumethiazide (Compound) binds CA4 (Gene) and CA4 (Gene) is bound by Celecoxib (Compound)
Bendroflumethiazide (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Celecoxib (Compound)
Bendroflumethiazide (Compound) binds CA4 (Gene) and CA4 (Gene) is downregulated by kidney cancer (Disease) and kidney cancer (Disease) is palliated by Celecoxib (Compound)
Bendroflumethiazide (Compound) binds CA2 (Gene) and CA2 (Gene) is associated with kidney cancer (Disease) and kidney cancer (Disease) is palliated by Celecoxib (Compound)
Bendroflumethiazide (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Etoricoxib (Compound) and Etoricoxib (Compound) resembles Celecoxib (Compound)
Bendroflumethiazide (Compound) resembles Benzthiazide (Compound) and Benzthiazide (Compound) binds CA9 (Gene) and CA9 (Gene) is bound by Celecoxib (Compound)
Bendroflumethiazide (Compound) binds CA2 (Gene) and CA2 (Gene) regulates RBM34 (Gene) and RBM34 (Gene) is downregulated by Celecoxib (Compound)
Bendroflumethiazide (Compound) resembles Cyclothiazide (Compound) and Cyclothiazide (Compound) binds CA2 (Gene) and CA2 (Gene) is bound by Celecoxib (Compound)
Bendroflumethiazide (Compound) resembles Polythiazide (Compound) and Polythiazide (Compound) causes Hyperglycaemia (Side Effect) and Hyperglycaemia (Side Effect) is caused by Celecoxib (Compound)
Bendroflumethiazide (Compound) treats hypertension (Disease) and hypertension (Disease) is associated with PTGS2 (Gene) and PTGS2 (Gene) is bound by Celecoxib (Compound)