DDInter1421 DDInter154
The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Azelastine is a phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position. It has a role as a H1-receptor antagonist, an anti-allergic agent, an anti-asthmatic drug, a bronchodilator agent, a platelet aggregation inhibitor and an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. It is a member of phthalazines, a tertiary amino compound and a member of monochlorobenzenes.
Pentazocine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clemastine
Clemastine {u} (Compound) resembles {v} (Compound) Azelastine
Pentazocine {u} (Compound) causes {v} (Side Effect) Feeling abnormal
Feeling abnormal {u} (Side Effect) is caused by {v} (Compound) Azelastine
Pentazocine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clemastine
Clemastine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) Azelastine
Pentazocine {u} (Compound) causes {v} (Side Effect) Feeling abnormal
Feeling abnormal {u} (Side Effect) is caused by {v} (Compound) Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) Azelastine
Pentazocine {u} (Compound) resembles {v} (Compound) Dezocine
Dezocine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clemastine
Clemastine {u} (Compound) resembles {v} (Compound) Azelastine
Pentazocine {u} (Compound) resembles {v} (Compound) Butorphanol
Butorphanol {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Azelastine
Pentazocine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clemastine
Clemastine {u} (Compound) resembles {v} (Compound) Buclizine
Buclizine {u} (Compound) resembles {v} (Compound) Azelastine
Pentazocine {u} (Compound) resembles {v} (Compound) Levorphanol
Levorphanol {u} (Compound) upregulates {v} (Gene) MAL
MAL {u} (Gene) is upregulated by {v} (Compound) Azelastine
Pentazocine {u} (Compound) binds {v} (Gene) SIGMAR1
SIGMAR1 {u} (Gene) is bound by {v} (Compound) Mazindol
Mazindol {u} (Compound) resembles {v} (Compound) Azelastine
Pentazocine {u} (Compound) resembles {v} (Compound) Levorphanol
Levorphanol {u} (Compound) downregulates {v} (Gene) DERA
DERA {u} (Gene) is downregulated by {v} (Compound) Azelastine
Pentazocine may cause a moderate interaction that could exacerbate diseases when taken with Clemastine and Clemastine (Compound) resembles Azelastine (Compound)
Pentazocine (Compound) causes Feeling abnormal (Side Effect) and Feeling abnormal (Side Effect) is caused by Azelastine (Compound)
Pentazocine may cause a moderate interaction that could exacerbate diseases when taken with Clemastine and Clemastine may cause a moderate interaction that could exacerbate diseases when taken with Loxapine and Loxapine (Compound) resembles Azelastine (Compound)
Pentazocine (Compound) causes Feeling abnormal (Side Effect) and Feeling abnormal (Side Effect) is caused by Loxapine (Compound) and Loxapine (Compound) resembles Azelastine (Compound)
Pentazocine (Compound) resembles Dezocine (Compound) and Dezocine may cause a moderate interaction that could exacerbate diseases when taken with Clemastine and Clemastine (Compound) resembles Azelastine (Compound)
Pentazocine (Compound) resembles Butorphanol (Compound) and Butorphanol (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Azelastine (Compound)
Pentazocine may cause a moderate interaction that could exacerbate diseases when taken with Clemastine and Clemastine (Compound) resembles Buclizine (Compound) and Buclizine (Compound) resembles Azelastine (Compound)
Pentazocine (Compound) resembles Levorphanol (Compound) and Levorphanol (Compound) upregulates MAL (Gene) and MAL (Gene) is upregulated by Azelastine (Compound)
Pentazocine (Compound) binds SIGMAR1 (Gene) and SIGMAR1 (Gene) is bound by Mazindol (Compound) and Mazindol (Compound) resembles Azelastine (Compound)
Pentazocine (Compound) resembles Levorphanol (Compound) and Levorphanol (Compound) downregulates DERA (Gene) and DERA (Gene) is downregulated by Azelastine (Compound)