DDInter195 DDInter624
Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.
Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1. For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with zidovudine or tenofovir is the preferred NNRTI-based regimen. Efavirenz is also used in combination with other antiretroviral agents as part of an expanded postexposure prophylaxis regimen to prevent HIV transmission for those exposed to materials associated with a high risk for HIV transmission.
Betamethasone {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Efavirenz
Betamethasone {u} (Compound) downregulates {v} (Gene) CCDC86
CCDC86 {u} (Gene) is downregulated by {v} (Compound) Efavirenz
Betamethasone {u} (Compound) causes {v} (Side Effect) Hallucination
Hallucination {u} (Side Effect) is caused by {v} (Compound) Efavirenz
Betamethasone {u} (Compound) downregulates {v} (Gene) CCDC86
CCDC86 {u} (Gene) regulates {v} (Gene) OXA1L
OXA1L {u} (Gene) is downregulated by {v} (Compound) Efavirenz
Betamethasone {u} (Compound) upregulates {v} (Gene) SATB1
SATB1 {u} (Gene) is downregulated by {v} (Disease) acquired immunodeficiency syndrome
acquired immunodeficiency syndrome {u} (Disease) is treated by {v} (Compound) Efavirenz
Betamethasone {u} (Compound) upregulates {v} (Gene) SATB1
SATB1 {u} (Gene) is regulated by {v} (Gene) TBX2
TBX2 {u} (Gene) is upregulated by {v} (Compound) Efavirenz
Betamethasone {u} (Compound) downregulates {v} (Gene) IFNAR1
IFNAR1 {u} (Gene) is downregulated by {v} (Disease) acquired immunodeficiency syndrome
acquired immunodeficiency syndrome {u} (Disease) is treated by {v} (Compound) Efavirenz
Betamethasone {u} (Compound) upregulates {v} (Gene) TGFBR2
TGFBR2 {u} (Gene) regulates {v} (Gene) PFN1
PFN1 {u} (Gene) is downregulated by {v} (Compound) Efavirenz
Betamethasone {u} (Compound) downregulates {v} (Gene) IFNAR1
IFNAR1 {u} (Gene) is regulated by {v} (Gene) POLR2I
POLR2I {u} (Gene) is downregulated by {v} (Compound) Efavirenz
Betamethasone {u} (Compound) upregulates {v} (Gene) MYC
MYC {u} (Gene) interacts with {v} (Gene) RFC2
RFC2 {u} (Gene) is downregulated by {v} (Compound) Efavirenz
Betamethasone (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Efavirenz (Compound)
Betamethasone (Compound) downregulates CCDC86 (Gene) and CCDC86 (Gene) is downregulated by Efavirenz (Compound)
Betamethasone (Compound) causes Hallucination (Side Effect) and Hallucination (Side Effect) is caused by Efavirenz (Compound)
Betamethasone (Compound) downregulates CCDC86 (Gene) and CCDC86 (Gene) regulates OXA1L (Gene) and OXA1L (Gene) is downregulated by Efavirenz (Compound)
Betamethasone (Compound) upregulates SATB1 (Gene) and SATB1 (Gene) is downregulated by acquired immunodeficiency syndrome (Disease) and acquired immunodeficiency syndrome (Disease) is treated by Efavirenz (Compound)
Betamethasone (Compound) upregulates SATB1 (Gene) and SATB1 (Gene) is regulated by TBX2 (Gene) and TBX2 (Gene) is upregulated by Efavirenz (Compound)
Betamethasone (Compound) downregulates IFNAR1 (Gene) and IFNAR1 (Gene) is downregulated by acquired immunodeficiency syndrome (Disease) and acquired immunodeficiency syndrome (Disease) is treated by Efavirenz (Compound)
Betamethasone (Compound) upregulates TGFBR2 (Gene) and TGFBR2 (Gene) regulates PFN1 (Gene) and PFN1 (Gene) is downregulated by Efavirenz (Compound)
Betamethasone (Compound) downregulates IFNAR1 (Gene) and IFNAR1 (Gene) is regulated by POLR2I (Gene) and POLR2I (Gene) is downregulated by Efavirenz (Compound)
Betamethasone (Compound) upregulates MYC (Gene) and MYC (Gene) interacts with RFC2 (Gene) and RFC2 (Gene) is downregulated by Efavirenz (Compound)