DDInter1158 DDInter288
An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease. Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical agent. Throughout the late seventies and the eighties, important research initiatives developed stable mesalazine formulations like the eudragit-S coating of Asacol brand mesalazine and the Pentasa brand's encapsulation of mesalazine within microgranules. In the present day, contemporary research regarding novel methods to stabilize mesalazine continues and interest in the agent's capacity to decrease inflammatory activity and subsequently potentially reduce the risk of colorectal cancer in conditions like ulcerative colitis is maintained.[A174019,A174022]
Cyclic peptide antibiotic similar to viomycin. It is produced by Streptomyces capreolus.
Mesalazine {u} (Compound) causes {v} (Side Effect) Urine analysis abnormal
Urine analysis abnormal {u} (Side Effect) is caused by {v} (Compound) Capreomycin
Mesalazine {u} (Compound) resembles {v} (Compound) Olsalazine
Olsalazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Capreomycin
Mesalazine {u} (Compound) causes {v} (Side Effect) Urine analysis abnormal
Urine analysis abnormal {u} (Side Effect) is caused by {v} (Compound) Lansoprazole
Lansoprazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Capreomycin
Mesalazine {u} (Compound) resembles {v} (Compound) Salicylate-sodium
Salicylate-sodium {u} (Compound) causes {v} (Side Effect) Oliguria
Oliguria {u} (Side Effect) is caused by {v} (Compound) Capreomycin
Mesalazine {u} (Compound) resembles {v} (Compound) Olsalazine
Olsalazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Polymyxin B
Polymyxin B {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Capreomycin
Mesalazine {u} (Compound) causes {v} (Side Effect) Hepatocellular injury
Hepatocellular injury {u} (Side Effect) is caused by {v} (Compound) Pantoprazole
Pantoprazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Capreomycin
Mesalazine {u} (Compound) causes {v} (Side Effect) Hypocalcaemia
Hypocalcaemia {u} (Side Effect) is caused by {v} (Compound) Sirolimus
Sirolimus {u} may lead to a major life threatening interaction when taken with {v} Capreomycin
Mesalazine {u} (Compound) resembles {v} (Compound) Levodopa
Levodopa {u} (Compound) causes {v} (Side Effect) Urticaria
Urticaria {u} (Side Effect) is caused by {v} (Compound) Capreomycin
Mesalazine {u} (Compound) resembles {v} (Compound) Olsalazine
Olsalazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Exenatide
Exenatide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Capreomycin
Mesalazine {u} (Compound) treats {v} (Disease) ulcerative colitis
ulcerative colitis {u} (Disease) is treated by {v} (Compound) Dexamethasone
Dexamethasone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Capreomycin
Mesalazine (Compound) causes Urine analysis abnormal (Side Effect) and Urine analysis abnormal (Side Effect) is caused by Capreomycin (Compound)
Mesalazine (Compound) resembles Olsalazine (Compound) and Olsalazine may cause a moderate interaction that could exacerbate diseases when taken with Capreomycin
Mesalazine (Compound) causes Urine analysis abnormal (Side Effect) and Urine analysis abnormal (Side Effect) is caused by Lansoprazole (Compound) and Lansoprazole may cause a moderate interaction that could exacerbate diseases when taken with Capreomycin
Mesalazine (Compound) resembles Salicylate-sodium (Compound) and Salicylate-sodium (Compound) causes Oliguria (Side Effect) and Oliguria (Side Effect) is caused by Capreomycin (Compound)
Mesalazine (Compound) resembles Olsalazine (Compound) and Olsalazine may cause a moderate interaction that could exacerbate diseases when taken with Polymyxin B and Polymyxin B may cause a moderate interaction that could exacerbate diseases when taken with Capreomycin
Mesalazine (Compound) causes Hepatocellular injury (Side Effect) and Hepatocellular injury (Side Effect) is caused by Pantoprazole (Compound) and Pantoprazole may cause a moderate interaction that could exacerbate diseases when taken with Capreomycin
Mesalazine (Compound) causes Hypocalcaemia (Side Effect) and Hypocalcaemia (Side Effect) is caused by Sirolimus (Compound) and Sirolimus may lead to a major life threatening interaction when taken with Capreomycin
Mesalazine (Compound) resembles Levodopa (Compound) and Levodopa (Compound) causes Urticaria (Side Effect) and Urticaria (Side Effect) is caused by Capreomycin (Compound)
Mesalazine (Compound) resembles Olsalazine (Compound) and Olsalazine may cause a moderate interaction that could exacerbate diseases when taken with Exenatide and Exenatide may cause a moderate interaction that could exacerbate diseases when taken with Capreomycin
Mesalazine (Compound) treats ulcerative colitis (Disease) and ulcerative colitis (Disease) is treated by Dexamethasone (Compound) and Dexamethasone may cause a moderate interaction that could exacerbate diseases when taken with Capreomycin