DDInter1164 DDInter248
Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173] Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels. Another well-known benefit of this drug is modest weight loss, making it an effective choice for obese patients type II diabetes. Metformin was first approved in Canada in 1972, and received subsequent FDA approval in the US in 1995.
Bumetanide is a sulfamyl diuretic.
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Bumetanide
Metformin {u} (Compound) causes {v} (Side Effect) Pancreatitis
Pancreatitis {u} (Side Effect) is caused by {v} (Compound) Bumetanide
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Furosemide {u} (Compound) resembles {v} (Compound) Bumetanide
Metformin {u} (Compound) causes {v} (Side Effect) Pancreatitis
Pancreatitis {u} (Side Effect) is caused by {v} (Compound) Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Bumetanide
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Metolazone
Metolazone {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Bumetanide
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Bumetanide
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) binds {v} (Gene) CA12
CA12 {u} (Gene) is bound by {v} (Compound) Bumetanide
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) causes {v} (Side Effect) Blood uric acid increased
Blood uric acid increased {u} (Side Effect) is caused by {v} (Compound) Bumetanide
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Warfarin
Warfarin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Bumetanide
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Trospium
Trospium {u} may cause a minor interaction that can limit clinical effects when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Bumetanide
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) resembles Bumetanide (Compound)
Metformin (Compound) causes Pancreatitis (Side Effect) and Pancreatitis (Side Effect) is caused by Bumetanide (Compound)
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) resembles Furosemide (Compound) and Furosemide (Compound) resembles Bumetanide (Compound)
Metformin (Compound) causes Pancreatitis (Side Effect) and Pancreatitis (Side Effect) is caused by Indapamide (Compound) and Indapamide (Compound) resembles Bumetanide (Compound)
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Metolazone and Metolazone (Compound) resembles Indapamide (Compound) and Indapamide (Compound) resembles Bumetanide (Compound)
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) treats hypertension (Disease) and hypertension (Disease) is treated by Bumetanide (Compound)
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) binds CA12 (Gene) and CA12 (Gene) is bound by Bumetanide (Compound)
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) causes Blood uric acid increased (Side Effect) and Blood uric acid increased (Side Effect) is caused by Bumetanide (Compound)
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Warfarin and Warfarin may cause a minor interaction that can limit clinical effects when taken with Indapamide and Indapamide (Compound) resembles Bumetanide (Compound)
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Trospium and Trospium may cause a minor interaction that can limit clinical effects when taken with Indapamide and Indapamide (Compound) resembles Bumetanide (Compound)