DDInter350 DDInter1936
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)
Chlorambucil {u} (Compound) treats {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is treated by {v} (Compound) Vinblastine
Chlorambucil {u} (Compound) upregulates {v} (Gene) PMAIP1
PMAIP1 {u} (Gene) is upregulated by {v} (Compound) Vinblastine
Chlorambucil {u} (Compound) downregulates {v} (Gene) LBR
LBR {u} (Gene) is upregulated by {v} (Compound) Vinblastine
Chlorambucil {u} (Compound) downregulates {v} (Gene) MCM3
MCM3 {u} (Gene) is downregulated by {v} (Compound) Vinblastine
Chlorambucil {u} (Compound) upregulates {v} (Gene) SESN1
SESN1 {u} (Gene) is downregulated by {v} (Compound) Vinblastine
Chlorambucil {u} (Compound) causes {v} (Side Effect) Vomiting
Vomiting {u} (Side Effect) is caused by {v} (Compound) Vinblastine
Chlorambucil {u} (Compound) resembles {v} (Compound) Melphalan
Melphalan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Vinblastine
Chlorambucil {u} (Compound) treats {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is treated by {v} (Compound) Vincristine
Vincristine {u} (Compound) resembles {v} (Compound) Vinblastine
Chlorambucil {u} (Compound) treats {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Vinorelbine
Vinorelbine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Vinblastine
Chlorambucil {u} (Compound) treats {v} (Disease) testicular cancer
testicular cancer {u} (Disease) resembles {v} (Disease) kidney cancer
kidney cancer {u} (Disease) is treated by {v} (Compound) Vinblastine
Chlorambucil (Compound) treats hematologic cancer (Disease) and hematologic cancer (Disease) is treated by Vinblastine (Compound)
Chlorambucil (Compound) upregulates PMAIP1 (Gene) and PMAIP1 (Gene) is upregulated by Vinblastine (Compound)
Chlorambucil (Compound) downregulates LBR (Gene) and LBR (Gene) is upregulated by Vinblastine (Compound)
Chlorambucil (Compound) downregulates MCM3 (Gene) and MCM3 (Gene) is downregulated by Vinblastine (Compound)
Chlorambucil (Compound) upregulates SESN1 (Gene) and SESN1 (Gene) is downregulated by Vinblastine (Compound)
Chlorambucil (Compound) causes Vomiting (Side Effect) and Vomiting (Side Effect) is caused by Vinblastine (Compound)
Chlorambucil (Compound) resembles Melphalan (Compound) and Melphalan may cause a moderate interaction that could exacerbate diseases when taken with Vinblastine
Chlorambucil (Compound) treats hematologic cancer (Disease) and hematologic cancer (Disease) is treated by Vincristine (Compound) and Vincristine (Compound) resembles Vinblastine (Compound)
Chlorambucil (Compound) treats breast cancer (Disease) and breast cancer (Disease) is treated by Vinorelbine (Compound) and Vinorelbine may cause a moderate interaction that could exacerbate diseases when taken with Vinblastine
Chlorambucil (Compound) treats testicular cancer (Disease) and testicular cancer (Disease) resembles kidney cancer (Disease) and kidney cancer (Disease) is treated by Vinblastine (Compound)