DDInter718 DDInter1676
Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil]. Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.[L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.
Siponimod, also known as _Mayzent_, by Novartis, is a new drug formulated for the management of Multiple Sclerosis (MS). It was approved by the FDA on March 26, 2019 and by Health Canada on February 20, 2020. This drug is considered a _sphingosine-1-phosphate (S1P) receptor modulator_ and is thought to play a role in suppressing the central nervous system inflammation that is associated with MS [FDA label]. Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system that is chronic and inflammatory, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of life. Symptoms may include but are not limited to fatigue, gait changes, bowel or bladder dysfunction, abnormal muscle twitching, vision disturbance, and depressing or mood swings. MS is one of the most common causes of neurological disability in young adults and is found to occur more frequently in women than in men.[A176474,L5792]
Fenofibrate {u} (Compound) resembles {v} (Compound) Etofibrate
Fenofibrate {u} (Compound) treats {v} (Disease) coronary artery disease
Fenofibrate {u} (Compound) binds {v} (Gene) CYP2C8
Fenofibrate {u} (Compound) upregulates {v} (Gene) SOX2
Fenofibrate {u} (Compound) is included by {v} (Pharmacologic Class) Peroxisome Proliferator-activated Receptor alpha Agonists
Fenofibrate {u} (Compound) downregulates {v} (Gene) PSMD9
Fenofibrate {u} (Compound) causes {v} (Side Effect) Hyperhidrosis
Fenofibrate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Zafirlukast
Fenofibrate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Insulin degludec
Fenofibrate {u} may lead to a major life threatening interaction when taken with {v} Teriflunomide
Fenofibrate (Compound) resembles Etofibrate (Compound)
Fenofibrate (Compound) treats coronary artery disease (Disease)
Fenofibrate (Compound) binds CYP2C8 (Gene)
Fenofibrate (Compound) upregulates SOX2 (Gene)
Fenofibrate (Compound) is included by Peroxisome Proliferator-activated Receptor alpha Agonists (Pharmacologic Class)
Fenofibrate (Compound) downregulates PSMD9 (Gene)
Fenofibrate (Compound) causes Hyperhidrosis (Side Effect)
Fenofibrate may cause a moderate interaction that could exacerbate diseases when taken with Zafirlukast
Fenofibrate may cause a moderate interaction that could exacerbate diseases when taken with Insulin degludec
Fenofibrate may lead to a major life threatening interaction when taken with Teriflunomide