DDInter758 DDInter1016
Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI). It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies.
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose]. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. [sucrose]). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in patients with cirrhosis.[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.
Fluoxetine {u} (Compound) resembles {v} (Compound) Orphenadrine
Fluoxetine {u} (Compound) resembles {v} (Compound) Duloxetine
Fluoxetine {u} (Compound) binds {v} (Gene) CYP2D6
Fluoxetine {u} (Compound) upregulates {v} (Gene) ALDOC
Fluoxetine {u} (Compound) palliates {v} (Disease) schizophrenia
Fluoxetine {u} (Compound) downregulates {v} (Gene) RPS4Y1
Fluoxetine {u} (Compound) causes {v} (Side Effect) Cystitis
Fluoxetine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metronidazole
Fluoxetine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Levothyroxine
Fluoxetine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mepyramine
Fluoxetine (Compound) resembles Orphenadrine (Compound)
Fluoxetine (Compound) resembles Duloxetine (Compound)
Fluoxetine (Compound) binds CYP2D6 (Gene)
Fluoxetine (Compound) upregulates ALDOC (Gene)
Fluoxetine (Compound) palliates schizophrenia (Disease)
Fluoxetine (Compound) downregulates RPS4Y1 (Gene)
Fluoxetine (Compound) causes Cystitis (Side Effect)
Fluoxetine may cause a minor interaction that can limit clinical effects when taken with Metronidazole
Fluoxetine may cause a minor interaction that can limit clinical effects when taken with Levothyroxine
Fluoxetine may cause a moderate interaction that could exacerbate diseases when taken with Mepyramine