DDInter255 DDInter778
Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought about. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.
Fosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.
Busulfan {u} (Compound) causes {v} (Side Effect) Abdominal distension
Abdominal distension {u} (Side Effect) is caused by {v} (Compound) Fosaprepitant
Busulfan {u} (Compound) causes {v} (Side Effect) Abdominal distension
Abdominal distension {u} (Side Effect) is caused by {v} (Compound) Aprepitant
Aprepitant {u} (Compound) resembles {v} (Compound) Fosaprepitant
Busulfan {u} (Compound) causes {v} (Side Effect) Neoplasm malignant
Neoplasm malignant {u} (Side Effect) is caused by {v} (Compound) Sibutramine
Sibutramine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Fosaprepitant
Busulfan {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Aprepitant
Aprepitant {u} (Compound) resembles {v} (Compound) Fosaprepitant
Busulfan {u} (Compound) causes {v} (Side Effect) Mediastinal disorder
Mediastinal disorder {u} (Side Effect) is caused by {v} (Compound) Miconazole
Miconazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fosaprepitant
Busulfan {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Sibutramine
Sibutramine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Fosaprepitant
Busulfan {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Miconazole
Miconazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fosaprepitant
Busulfan {u} (Compound) causes {v} (Side Effect) Menopausal symptoms
Menopausal symptoms {u} (Side Effect) is caused by {v} (Compound) Enzalutamide
Enzalutamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fosaprepitant
Busulfan {u} (Compound) causes {v} (Side Effect) Menopausal symptoms
Menopausal symptoms {u} (Side Effect) is caused by {v} (Compound) Cilostazol
Cilostazol {u} may lead to a major life threatening interaction when taken with {v} Fosaprepitant
Busulfan {u} (Compound) causes {v} (Side Effect) Blood bilirubin increased
Blood bilirubin increased {u} (Side Effect) is caused by {v} (Compound) Ivacaftor
Ivacaftor {u} may lead to a major life threatening interaction when taken with {v} Fosaprepitant
Busulfan (Compound) causes Abdominal distension (Side Effect) and Abdominal distension (Side Effect) is caused by Fosaprepitant (Compound)
Busulfan (Compound) causes Abdominal distension (Side Effect) and Abdominal distension (Side Effect) is caused by Aprepitant (Compound) and Aprepitant (Compound) resembles Fosaprepitant (Compound)
Busulfan (Compound) causes Neoplasm malignant (Side Effect) and Neoplasm malignant (Side Effect) is caused by Sibutramine (Compound) and Sibutramine may cause a minor interaction that can limit clinical effects when taken with Fosaprepitant
Busulfan (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Aprepitant (Compound) and Aprepitant (Compound) resembles Fosaprepitant (Compound)
Busulfan (Compound) causes Mediastinal disorder (Side Effect) and Mediastinal disorder (Side Effect) is caused by Miconazole (Compound) and Miconazole may cause a moderate interaction that could exacerbate diseases when taken with Fosaprepitant
Busulfan (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Sibutramine (Compound) and Sibutramine may cause a minor interaction that can limit clinical effects when taken with Fosaprepitant
Busulfan (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Miconazole (Compound) and Miconazole may cause a moderate interaction that could exacerbate diseases when taken with Fosaprepitant
Busulfan (Compound) causes Menopausal symptoms (Side Effect) and Menopausal symptoms (Side Effect) is caused by Enzalutamide (Compound) and Enzalutamide may cause a moderate interaction that could exacerbate diseases when taken with Fosaprepitant
Busulfan (Compound) causes Menopausal symptoms (Side Effect) and Menopausal symptoms (Side Effect) is caused by Cilostazol (Compound) and Cilostazol may lead to a major life threatening interaction when taken with Fosaprepitant
Busulfan (Compound) causes Blood bilirubin increased (Side Effect) and Blood bilirubin increased (Side Effect) is caused by Ivacaftor (Compound) and Ivacaftor may lead to a major life threatening interaction when taken with Fosaprepitant