DDInter1873 DDInter536
Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.
Dichloralphenazone is a sedative composed of chloral hydrate and phenazone. It is typically found in combination products Nodolor and Midrin containing [isometheptene] and [acetaminophen] used for the relief of tension and vascular headaches. It is a US Schedule IV drug and its clinical use is limited.
Trimethobenzamide {u} (Compound) resembles {v} (Compound) Bevantolol
Trimethobenzamide {u} (Compound) resembles {v} (Compound) Cisapride
Trimethobenzamide {u} (Compound) upregulates {v} (Gene) HIST1H2BK
Trimethobenzamide {u} (Compound) is included by {v} (Pharmacologic Class) Emesis Suppression
Trimethobenzamide {u} (Compound) causes {v} (Side Effect) Disorientation
Trimethobenzamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Midazolam
Trimethobenzamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Duloxetine
Trimethobenzamide {u} may lead to a major life threatening interaction when taken with {v} Dextropropoxyphene
Trimethobenzamide (Compound) resembles Bevantolol (Compound)
Trimethobenzamide (Compound) resembles Cisapride (Compound)
Trimethobenzamide (Compound) upregulates HIST1H2BK (Gene)
Trimethobenzamide (Compound) is included by Emesis Suppression (Pharmacologic Class)
Trimethobenzamide (Compound) causes Disorientation (Side Effect)
Trimethobenzamide may cause a moderate interaction that could exacerbate diseases when taken with Midazolam
Trimethobenzamide may cause a moderate interaction that could exacerbate diseases when taken with Duloxetine
Trimethobenzamide may lead to a major life threatening interaction when taken with Dextropropoxyphene