DDInter993 DDInter957
Isradipine belongs to the dihydropyridine (DHP) class of calcium channel blockers (CCBs), the most widely used class of CCBs. It is structurally related to felodipine, nifedipine, and nimodipine and is the most potent calcium-channel blocking agent of the DHP class. Isradipine binds to calcium channels with high affinity and specificity and inhibits calcium flux into cardiac and arterial smooth muscle cells. It exhibits greater selectivity towards arterial smooth muscle cells owing to alternative splicing of the alpha-1 subunit of the channel and increased prevalence of inactive channels in smooth muscle cells. Isradipine may be used to treat mild to moderate essential hypertension.
Iodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.
Isradipine {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Isradipine {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Diatrizoate
Diatrizoate {u} (Compound) resembles {v} (Compound) Iodipamide
Isradipine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ibuprofen
Ibuprofen {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Isradipine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ibuprofen
Ibuprofen {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Isradipine {u} may lead to a major life threatening interaction when taken with {v} Enzalutamide
Enzalutamide {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Isradipine {u} may lead to a major life threatening interaction when taken with {v} Enzalutamide
Enzalutamide {u} (Compound) causes {v} (Side Effect) Headache
Headache {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Isradipine {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is associated with {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Isradipine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Thalidomide
Thalidomide {u} (Compound) downregulates {v} (Gene) GRB7
GRB7 {u} (Gene) is downregulated by {v} (Compound) Iodipamide
Isradipine {u} (Compound) resembles {v} (Compound) Nisoldipine
Nisoldipine {u} (Compound) downregulates {v} (Gene) NVL
NVL {u} (Gene) is downregulated by {v} (Compound) Iodipamide
Isradipine {u} (Compound) resembles {v} (Compound) Nisoldipine
Nisoldipine {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Isradipine (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Iodipamide (Compound)
Isradipine (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Diatrizoate (Compound) and Diatrizoate (Compound) resembles Iodipamide (Compound)
Isradipine may cause a moderate interaction that could exacerbate diseases when taken with Ibuprofen and Ibuprofen (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Isradipine may cause a moderate interaction that could exacerbate diseases when taken with Ibuprofen and Ibuprofen (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Iodipamide (Compound)
Isradipine may lead to a major life threatening interaction when taken with Enzalutamide and Enzalutamide (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Isradipine may lead to a major life threatening interaction when taken with Enzalutamide and Enzalutamide (Compound) causes Headache (Side Effect) and Headache (Side Effect) is caused by Iodipamide (Compound)
Isradipine (Compound) treats hypertension (Disease) and hypertension (Disease) is associated with ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Isradipine may cause a moderate interaction that could exacerbate diseases when taken with Thalidomide and Thalidomide (Compound) downregulates GRB7 (Gene) and GRB7 (Gene) is downregulated by Iodipamide (Compound)
Isradipine (Compound) resembles Nisoldipine (Compound) and Nisoldipine (Compound) downregulates NVL (Gene) and NVL (Gene) is downregulated by Iodipamide (Compound)
Isradipine (Compound) resembles Nisoldipine (Compound) and Nisoldipine (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Iodipamide (Compound)