DDInter248 DDInter298
Bumetanide is a sulfamyl diuretic.
Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma. Early clinical studies of carboplatin were performed in 1982. Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.
Bumetanide {u} (Compound) binds {v} (Gene) PTGS2
PTGS2 {u} (Gene) is associated with {v} (Disease) esophageal cancer
esophageal cancer {u} (Disease) is treated by {v} (Compound) Carboplatin
Bumetanide {u} (Compound) binds {v} (Gene) CA14
CA14 {u} (Gene) is downregulated by {v} (Disease) ovarian cancer
ovarian cancer {u} (Disease) is treated by {v} (Compound) Carboplatin
Bumetanide {u} (Compound) downregulates {v} (Gene) COTL1
COTL1 {u} (Gene) is associated with {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Carboplatin
Bumetanide {u} (Compound) downregulates {v} (Gene) COTL1
COTL1 {u} (Gene) is regulated by {v} (Gene) GSTM1
GSTM1 {u} (Gene) is bound by {v} (Compound) Carboplatin
Bumetanide {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is associated with {v} (Gene) GSTM1
GSTM1 {u} (Gene) is bound by {v} (Compound) Carboplatin
Bumetanide {u} (Compound) binds {v} (Gene) PTGS2
PTGS2 {u} (Gene) is regulated by {v} (Gene) SOD1
SOD1 {u} (Gene) is bound by {v} (Compound) Carboplatin
Bumetanide {u} (Compound) resembles {v} (Compound) Furosemide
Furosemide {u} (Compound) binds {v} (Gene) ABCC2
ABCC2 {u} (Gene) is bound by {v} (Compound) Carboplatin
Bumetanide {u} (Compound) palliates {v} (Disease) chronic kidney failure
chronic kidney failure {u} (Disease) is associated with {v} (Gene) ABCC2
ABCC2 {u} (Gene) is bound by {v} (Compound) Carboplatin
Bumetanide {u} (Compound) resembles {v} (Compound) Furosemide
Furosemide {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Carboplatin
Bumetanide (Compound) binds PTGS2 (Gene) and PTGS2 (Gene) is associated with esophageal cancer (Disease) and esophageal cancer (Disease) is treated by Carboplatin (Compound)
Bumetanide (Compound) binds CA14 (Gene) and CA14 (Gene) is downregulated by ovarian cancer (Disease) and ovarian cancer (Disease) is treated by Carboplatin (Compound)
Bumetanide (Compound) downregulates COTL1 (Gene) and COTL1 (Gene) is associated with breast cancer (Disease) and breast cancer (Disease) is treated by Carboplatin (Compound)
Bumetanide (Compound) downregulates COTL1 (Gene) and COTL1 (Gene) is regulated by GSTM1 (Gene) and GSTM1 (Gene) is bound by Carboplatin (Compound)
Bumetanide (Compound) treats hypertension (Disease) and hypertension (Disease) is associated with GSTM1 (Gene) and GSTM1 (Gene) is bound by Carboplatin (Compound)
Bumetanide (Compound) binds PTGS2 (Gene) and PTGS2 (Gene) is regulated by SOD1 (Gene) and SOD1 (Gene) is bound by Carboplatin (Compound)
Bumetanide (Compound) resembles Furosemide (Compound) and Furosemide (Compound) binds ABCC2 (Gene) and ABCC2 (Gene) is bound by Carboplatin (Compound)
Bumetanide (Compound) palliates chronic kidney failure (Disease) and chronic kidney failure (Disease) is associated with ABCC2 (Gene) and ABCC2 (Gene) is bound by Carboplatin (Compound)
Bumetanide (Compound) resembles Furosemide (Compound) and Furosemide (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Carboplatin (Compound)