DDInter1793 DDInter1960
A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. This piperazine phenothiazine does not prevent vertigo or motion sickness. (From AMA Drug Evaluations Annual, 1994, p457)
Ziconotide (also known as SNX-111) is a neurotoxic peptide derived from the cone snail _Conus magus_ comprising 25 amino acids with three disulphide bonds.[A202835, L13389] Other such peptides, collectively termed conotoxins, exist, and some have shown efficacy in binding specific subsets of calcium channels; ziconotide is used in part because it can be synthesized without loss of proper bond formation or structural elements.[A202829, A202832] Ziconotide is used to manage severe chronic pain refractory to other methods, through its ability to inhibit N-type calcium channels involved in nociceptive signalling.[A202829, A202835, A202838, A202841, A202850, A202859, L13389] Ziconotide was granted FDA approval on December 28, 2004 for marketing by TerSera therapeutics LLC. under the name Prialt. To date, ziconotide is the only calcium channel blocking peptide approved for use by the FDA.
Thiethylperazine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium carbonate
Thiethylperazine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Sucralfate
Thiethylperazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sotalol
Thiethylperazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pregabalin
Thiethylperazine {u} may lead to a major life threatening interaction when taken with {v} Iohexol
Thiethylperazine {u} may lead to a major life threatening interaction when taken with {v} Tramadol
Thiethylperazine may cause a minor interaction that can limit clinical effects when taken with Magnesium carbonate
Thiethylperazine may cause a minor interaction that can limit clinical effects when taken with Sucralfate
Thiethylperazine may cause a moderate interaction that could exacerbate diseases when taken with Sotalol
Thiethylperazine may cause a moderate interaction that could exacerbate diseases when taken with Pregabalin
Thiethylperazine may lead to a major life threatening interaction when taken with Iohexol
Thiethylperazine may lead to a major life threatening interaction when taken with Tramadol