DDInter48 DDInter1425
Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints. This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals. Allopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and is frequently used in the treatment of chronic gout. It was initially approved by the FDA in 1966 and is now formulated by several manufacturers.
A potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
Allopurinol {u} (Compound) causes {v} (Side Effect) Foetor hepaticus
Foetor hepaticus {u} (Side Effect) is caused by {v} (Compound) Pentostatin
Allopurinol {u} (Compound) causes {v} (Side Effect) Foetor hepaticus
Foetor hepaticus {u} (Side Effect) is caused by {v} (Compound) Zidovudine
Zidovudine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pentostatin
Allopurinol {u} (Compound) causes {v} (Side Effect) Feeling abnormal
Feeling abnormal {u} (Side Effect) is caused by {v} (Compound) Decitabine
Decitabine {u} (Compound) resembles {v} (Compound) Pentostatin
Allopurinol {u} (Compound) causes {v} (Side Effect) Conjunctivitis
Conjunctivitis {u} (Side Effect) is caused by {v} (Compound) Idoxuridine
Idoxuridine {u} (Compound) resembles {v} (Compound) Pentostatin
Allopurinol {u} (Compound) causes {v} (Side Effect) Vasculitis
Vasculitis {u} (Side Effect) is caused by {v} (Compound) Ofloxacin
Ofloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Pentostatin
Allopurinol {u} (Compound) causes {v} (Side Effect) Muscle twitching
Muscle twitching {u} (Side Effect) is caused by {v} (Compound) Moxifloxacin
Moxifloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Pentostatin
Allopurinol {u} (Compound) causes {v} (Side Effect) Neuritis
Neuritis {u} (Side Effect) is caused by {v} (Compound) Vinblastine
Vinblastine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pentostatin
Allopurinol {u} (Compound) binds {v} (Gene) SLC22A8
SLC22A8 {u} (Gene) is bound by {v} (Compound) Ganciclovir
Ganciclovir {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pentostatin
Allopurinol {u} (Compound) causes {v} (Side Effect) Paralysis
Paralysis {u} (Side Effect) is caused by {v} (Compound) Cladribine
Cladribine {u} (Compound) resembles {v} (Compound) and {u} may lead to a major life threatening interaction when taken with {v} Pentostatin
Allopurinol {u} (Compound) causes {v} (Side Effect) Furuncle
Furuncle {u} (Side Effect) is caused by {v} (Compound) Deferiprone
Deferiprone {u} may lead to a major life threatening interaction when taken with {v} Pentostatin
Allopurinol (Compound) causes Foetor hepaticus (Side Effect) and Foetor hepaticus (Side Effect) is caused by Pentostatin (Compound)
Allopurinol (Compound) causes Foetor hepaticus (Side Effect) and Foetor hepaticus (Side Effect) is caused by Zidovudine (Compound) and Zidovudine may cause a moderate interaction that could exacerbate diseases when taken with Pentostatin
Allopurinol (Compound) causes Feeling abnormal (Side Effect) and Feeling abnormal (Side Effect) is caused by Decitabine (Compound) and Decitabine (Compound) resembles Pentostatin (Compound)
Allopurinol (Compound) causes Conjunctivitis (Side Effect) and Conjunctivitis (Side Effect) is caused by Idoxuridine (Compound) and Idoxuridine (Compound) resembles Pentostatin (Compound)
Allopurinol (Compound) causes Vasculitis (Side Effect) and Vasculitis (Side Effect) is caused by Ofloxacin (Compound) and Ofloxacin may cause a minor interaction that can limit clinical effects when taken with Pentostatin
Allopurinol (Compound) causes Muscle twitching (Side Effect) and Muscle twitching (Side Effect) is caused by Moxifloxacin (Compound) and Moxifloxacin may cause a minor interaction that can limit clinical effects when taken with Pentostatin
Allopurinol (Compound) causes Neuritis (Side Effect) and Neuritis (Side Effect) is caused by Vinblastine (Compound) and Vinblastine may cause a moderate interaction that could exacerbate diseases when taken with Pentostatin
Allopurinol (Compound) binds SLC22A8 (Gene) and SLC22A8 (Gene) is bound by Ganciclovir (Compound) and Ganciclovir may cause a moderate interaction that could exacerbate diseases when taken with Pentostatin
Allopurinol (Compound) causes Paralysis (Side Effect) and Paralysis (Side Effect) is caused by Cladribine (Compound) and Cladribine (Compound) resembles Pentostatin (Compound) and Cladribine may lead to a major life threatening interaction when taken with Pentostatin
Allopurinol (Compound) causes Furuncle (Side Effect) and Furuncle (Side Effect) is caused by Deferiprone (Compound) and Deferiprone may lead to a major life threatening interaction when taken with Pentostatin