DDInter1890 DDInter1396
Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to coat the tips of hunting arrows and darts, which were typically derived from plants of the genera _Chondrodendron_ and _Strychnos_. Tubocurarine is a benzylisoquinoline derivative and shares this structural backbone with a number of plant-derived alkaloids, including [morphine] and [papaverine]. It was first isolated by Harold King in 1935 and was used clinically to induce neuromuscular blockade during surgeries, particularly those involving the abdomen. Tubocurarine's clinical use was limited by its relatively long duration of action (30-60 minutes) and a number of significant side effects. Safer and more pharmacokinetically favorable non-depolarizing neuromuscular blockers,
An oligosaccharide antibiotic produced by various streptomyces. [PubChem]
Tubocurarine {u} may lead to a major life threatening interaction when taken with {v} Kanamycin
Kanamycin {u} (Compound) resembles {v} (Compound) Paromomycin
Tubocurarine {u} may lead to a major life threatening interaction when taken with {v} Neomycin
Neomycin {u} (Compound) resembles {v} (Compound) Paromomycin
Tubocurarine {u} may lead to a major life threatening interaction when taken with {v} Kanamycin
Kanamycin {u} (Compound) resembles {v} (Compound) Tobramycin
Tobramycin {u} (Compound) resembles {v} (Compound) Paromomycin
Tubocurarine {u} may lead to a major life threatening interaction when taken with {v} Kanamycin
Kanamycin {u} (Compound) resembles {v} (Compound) Amikacin
Amikacin {u} (Compound) resembles {v} (Compound) Paromomycin
Tubocurarine {u} may lead to a major life threatening interaction when taken with {v} Gentamicin
Gentamicin {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Kanamycin
Kanamycin {u} (Compound) resembles {v} (Compound) Paromomycin
Tubocurarine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Irinotecan
Irinotecan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lactulose
Lactulose {u} (Compound) resembles {v} (Compound) Paromomycin
Tubocurarine {u} may lead to a major life threatening interaction when taken with {v} Gentamicin
Gentamicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Neomycin
Neomycin {u} (Compound) resembles {v} (Compound) Paromomycin
Tubocurarine {u} may lead to a major life threatening interaction when taken with {v} Neomycin
Neomycin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Lactulose
Lactulose {u} (Compound) resembles {v} (Compound) Paromomycin
Tubocurarine {u} may lead to a major life threatening interaction when taken with {v} Kanamycin
Kanamycin {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Neomycin
Neomycin {u} (Compound) resembles {v} (Compound) Paromomycin
Tubocurarine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Prednisolone
Prednisolone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lactulose
Lactulose {u} (Compound) resembles {v} (Compound) Paromomycin
Tubocurarine may lead to a major life threatening interaction when taken with Kanamycin and Kanamycin (Compound) resembles Paromomycin (Compound)
Tubocurarine may lead to a major life threatening interaction when taken with Neomycin and Neomycin (Compound) resembles Paromomycin (Compound)
Tubocurarine may lead to a major life threatening interaction when taken with Kanamycin and Kanamycin (Compound) resembles Tobramycin (Compound) and Tobramycin (Compound) resembles Paromomycin (Compound)
Tubocurarine may lead to a major life threatening interaction when taken with Kanamycin and Kanamycin (Compound) resembles Amikacin (Compound) and Amikacin (Compound) resembles Paromomycin (Compound)
Tubocurarine may lead to a major life threatening interaction when taken with Gentamicin and Gentamicin (Compound) resembles Kanamycin (Compound) and Gentamicin may cause a moderate interaction that could exacerbate diseases when taken with Kanamycin and Kanamycin (Compound) resembles Paromomycin (Compound)
Tubocurarine may cause a minor interaction that can limit clinical effects when taken with Irinotecan and Irinotecan may cause a moderate interaction that could exacerbate diseases when taken with Lactulose and Lactulose (Compound) resembles Paromomycin (Compound)
Tubocurarine may lead to a major life threatening interaction when taken with Gentamicin and Gentamicin may cause a moderate interaction that could exacerbate diseases when taken with Neomycin and Neomycin (Compound) resembles Paromomycin (Compound)
Tubocurarine may lead to a major life threatening interaction when taken with Neomycin and Neomycin may cause a minor interaction that can limit clinical effects when taken with Lactulose and Lactulose (Compound) resembles Paromomycin (Compound)
Tubocurarine may lead to a major life threatening interaction when taken with Kanamycin and Kanamycin (Compound) resembles Neomycin (Compound) and Kanamycin may cause a moderate interaction that could exacerbate diseases when taken with Neomycin and Neomycin (Compound) resembles Paromomycin (Compound)
Tubocurarine may cause a moderate interaction that could exacerbate diseases when taken with Prednisolone and Prednisolone may cause a moderate interaction that could exacerbate diseases when taken with Lactulose and Lactulose (Compound) resembles Paromomycin (Compound)