DDInter1237 DDInter1376
Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26, 2020.[L12573,L12582] The US approval was followed by the approval in Canada on October 2, 2020. In November 2021, ozanimod was also approved by the European Commission for the treatment of adults with relapsing remitting multiple sclerosis.[L39377,L39382] MS is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Inflammatory bowel disease also a chronic inflammatory condition and can cause persistent abdominal pain, diarrhea, bloody stools, and vomiting. In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard in MS therapy. Studies involving patients with inflammatory bowel disease have also shown promising results.[A189318,A189342]
Moexipril {u} (Compound) resembles {v} (Compound) Ramipril
Moexipril {u} (Compound) resembles {v} (Compound) Donepezil
Moexipril {u} (Compound) treats {v} (Disease) hypertension
Moexipril {u} (Compound) binds {v} (Gene) SLC15A2
Moexipril {u} (Compound) downregulates {v} (Gene) RNF167
Moexipril {u} may cause a minor interaction that can limit clinical effects when taken with {v} Aluminum hydroxide
Moexipril {u} may cause a minor interaction that can limit clinical effects when taken with {v} Erythropoietin
Moexipril {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methotrexate
Moexipril {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nateglinide
Moexipril {u} may lead to a major life threatening interaction when taken with {v} Potassium gluconate
Moexipril (Compound) resembles Ramipril (Compound)
Moexipril (Compound) resembles Donepezil (Compound)
Moexipril (Compound) treats hypertension (Disease)
Moexipril (Compound) binds SLC15A2 (Gene)
Moexipril (Compound) downregulates RNF167 (Gene)
Moexipril may cause a minor interaction that can limit clinical effects when taken with Aluminum hydroxide
Moexipril may cause a minor interaction that can limit clinical effects when taken with Erythropoietin
Moexipril may cause a moderate interaction that could exacerbate diseases when taken with Methotrexate
Moexipril may cause a moderate interaction that could exacerbate diseases when taken with Nateglinide
Moexipril may lead to a major life threatening interaction when taken with Potassium gluconate