DDInter1759 DDInter246
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arterial blood pressure.[A1489,A1490] Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects.
Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994. It is also available in a combination product with [formoterol].
Telmisartan {u} (Compound) binds {v} (Gene) PPARG
PPARG {u} (Gene) is upregulated by {v} (Compound) Budesonide
Telmisartan {u} (Compound) causes {v} (Side Effect) Pain
Pain {u} (Side Effect) is caused by {v} (Compound) Budesonide
Telmisartan {u} (Compound) resembles {v} (Compound) Olmesartan
Olmesartan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Budesonide
Telmisartan {u} (Compound) resembles {v} (Compound) Azilsartan medoxomil
Azilsartan medoxomil {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Budesonide
Telmisartan {u} (Compound) binds {v} (Gene) PPARG
PPARG {u} (Gene) is upregulated by {v} (Compound) Triamcinolone
Triamcinolone {u} (Compound) resembles {v} (Compound) Budesonide
Telmisartan {u} (Compound) causes {v} (Side Effect) Pain
Pain {u} (Side Effect) is caused by {v} (Compound) Flunisolide
Flunisolide {u} (Compound) resembles {v} (Compound) Budesonide
Telmisartan {u} (Compound) causes {v} (Side Effect) Arthritis aggravated
Arthritis aggravated {u} (Side Effect) is caused by {v} (Compound) Eprosartan
Eprosartan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Budesonide
Telmisartan {u} (Compound) causes {v} (Side Effect) Somnolence
Somnolence {u} (Side Effect) is caused by {v} (Compound) Orciprenaline
Orciprenaline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Budesonide
Telmisartan {u} (Compound) causes {v} (Side Effect) Disorder sight
Disorder sight {u} (Side Effect) is caused by {v} (Compound) Crizotinib
Crizotinib {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Budesonide
Telmisartan {u} (Compound) resembles {v} (Compound) Olmesartan
Olmesartan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Betamethasone
Betamethasone {u} (Compound) resembles {v} (Compound) Budesonide
Telmisartan (Compound) binds PPARG (Gene) and PPARG (Gene) is upregulated by Budesonide (Compound)
Telmisartan (Compound) causes Pain (Side Effect) and Pain (Side Effect) is caused by Budesonide (Compound)
Telmisartan (Compound) resembles Olmesartan (Compound) and Olmesartan may cause a moderate interaction that could exacerbate diseases when taken with Budesonide
Telmisartan (Compound) resembles Azilsartan medoxomil (Compound) and Azilsartan medoxomil may cause a moderate interaction that could exacerbate diseases when taken with Budesonide
Telmisartan (Compound) binds PPARG (Gene) and PPARG (Gene) is upregulated by Triamcinolone (Compound) and Triamcinolone (Compound) resembles Budesonide (Compound)
Telmisartan (Compound) causes Pain (Side Effect) and Pain (Side Effect) is caused by Flunisolide (Compound) and Flunisolide (Compound) resembles Budesonide (Compound)
Telmisartan (Compound) causes Arthritis aggravated (Side Effect) and Arthritis aggravated (Side Effect) is caused by Eprosartan (Compound) and Eprosartan may cause a moderate interaction that could exacerbate diseases when taken with Budesonide
Telmisartan (Compound) causes Somnolence (Side Effect) and Somnolence (Side Effect) is caused by Orciprenaline (Compound) and Orciprenaline may cause a minor interaction that can limit clinical effects when taken with Budesonide
Telmisartan (Compound) causes Disorder sight (Side Effect) and Disorder sight (Side Effect) is caused by Crizotinib (Compound) and Crizotinib may cause a moderate interaction that could exacerbate diseases when taken with Budesonide
Telmisartan (Compound) resembles Olmesartan (Compound) and Olmesartan may cause a moderate interaction that could exacerbate diseases when taken with Betamethasone and Betamethasone (Compound) resembles Budesonide (Compound)