DDInter260 DDInter1448
Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. Cabergoline possesses potent agonist activity on dopamine D2 receptors.
Phentolamine is a reversible, non-selective alpha-adrenergic blocker that induces vasodilation. While initially introduced to the market for the treatment of hypertension, this clinical use was halted due to cardiovascular and gastrointestinal adverse effects with the prolonged use of large oral doses of phentolamine.[A261781, A261786] It has several therapeutic uses, including the treatment of hypertensive episodes, prevention of norepinephrine-induced extravasation, diagnosis of pheochromocytoma, reversal of soft-tissue anesthesia, and treatment of pharmacologically-induced mydriasis.[L48420, L48415, L48390] Phentolamine is administered intravenously, intramuscularly, submucosally, and topically.
Cabergoline {u} (Compound) binds {v} (Gene) ADRA2A
ADRA2A {u} (Gene) is bound by {v} (Compound) Phentolamine
Cabergoline {u} (Compound) downregulates {v} (Gene) RPS4Y1
RPS4Y1 {u} (Gene) is downregulated by {v} (Compound) Phentolamine
Cabergoline {u} (Compound) causes {v} (Side Effect) Diarrhoea
Diarrhoea {u} (Side Effect) is caused by {v} (Compound) Phentolamine
Cabergoline {u} (Compound) binds {v} (Gene) ADRA2A
ADRA2A {u} (Gene) is bound by {v} (Compound) Naphazoline
Naphazoline {u} (Compound) resembles {v} (Compound) Phentolamine
Cabergoline {u} (Compound) binds {v} (Gene) ADRA1B
ADRA1B {u} (Gene) interacts with {v} (Gene) ADRA1A
ADRA1A {u} (Gene) is bound by {v} (Compound) Phentolamine
Cabergoline {u} (Compound) downregulates {v} (Gene) RPS4Y1
RPS4Y1 {u} (Gene) is regulated by {v} (Gene) ADRA2C
ADRA2C {u} (Gene) is bound by {v} (Compound) Phentolamine
Cabergoline {u} (Compound) causes {v} (Side Effect) Diarrhoea
Diarrhoea {u} (Side Effect) is caused by {v} (Compound) Dronabinol
Dronabinol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phentolamine
Cabergoline {u} (Compound) causes {v} (Side Effect) Vomiting
Vomiting {u} (Side Effect) is caused by {v} (Compound) Fenoldopam
Fenoldopam {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phentolamine
Cabergoline {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Naphazoline
Naphazoline {u} (Compound) resembles {v} (Compound) Phentolamine
Cabergoline {u} (Compound) resembles {v} (Compound) Lisuride
Lisuride {u} (Compound) binds {v} (Gene) ADRA1D
ADRA1D {u} (Gene) is bound by {v} (Compound) Phentolamine
Cabergoline (Compound) binds ADRA2A (Gene) and ADRA2A (Gene) is bound by Phentolamine (Compound)
Cabergoline (Compound) downregulates RPS4Y1 (Gene) and RPS4Y1 (Gene) is downregulated by Phentolamine (Compound)
Cabergoline (Compound) causes Diarrhoea (Side Effect) and Diarrhoea (Side Effect) is caused by Phentolamine (Compound)
Cabergoline (Compound) binds ADRA2A (Gene) and ADRA2A (Gene) is bound by Naphazoline (Compound) and Naphazoline (Compound) resembles Phentolamine (Compound)
Cabergoline (Compound) binds ADRA1B (Gene) and ADRA1B (Gene) interacts with ADRA1A (Gene) and ADRA1A (Gene) is bound by Phentolamine (Compound)
Cabergoline (Compound) downregulates RPS4Y1 (Gene) and RPS4Y1 (Gene) is regulated by ADRA2C (Gene) and ADRA2C (Gene) is bound by Phentolamine (Compound)
Cabergoline (Compound) causes Diarrhoea (Side Effect) and Diarrhoea (Side Effect) is caused by Dronabinol (Compound) and Dronabinol may cause a moderate interaction that could exacerbate diseases when taken with Phentolamine
Cabergoline (Compound) causes Vomiting (Side Effect) and Vomiting (Side Effect) is caused by Fenoldopam (Compound) and Fenoldopam may cause a moderate interaction that could exacerbate diseases when taken with Phentolamine
Cabergoline (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Naphazoline (Compound) and Naphazoline (Compound) resembles Phentolamine (Compound)
Cabergoline (Compound) resembles Lisuride (Compound) and Lisuride (Compound) binds ADRA1D (Gene) and ADRA1D (Gene) is bound by Phentolamine (Compound)