DDInter948 DDInter1853
Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin A] (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant, and free radical-scavenging activities. It has been used in dermatology for many years to treat various skin conditions ranging from acne to wrinkles [A257474,A258185] and activates nuclear receptors to regulate epithelial cell growth and differentiation.[A257474,A257629,A257609] Tretinoin is given orally to treat acute promyelocytic leukemia and topically to treat skin conditions such as acne.[L45389,L34869,L45384]
Tretinoin {u} (Compound) resembles {v} (Compound) Isotretinoin
Tretinoin {u} (Compound) treats {v} (Disease) peripheral nervous system neoplasm
Tretinoin {u} (Compound) binds {v} (Gene) CYP1A1
Tretinoin {u} (Compound) upregulates {v} (Gene) DHRS3
Tretinoin {u} (Compound) is included by {v} (Pharmacologic Class) Retinoids
Tretinoin {u} (Compound) downregulates {v} (Gene) ATP6V1D
Tretinoin {u} (Compound) causes {v} (Side Effect) Agranulocytosis
Tretinoin (Compound) resembles Isotretinoin (Compound)
Tretinoin (Compound) treats peripheral nervous system neoplasm (Disease)
Tretinoin (Compound) binds CYP1A1 (Gene)
Tretinoin (Compound) upregulates DHRS3 (Gene)
Tretinoin (Compound) is included by Retinoids (Pharmacologic Class)
Tretinoin (Compound) downregulates ATP6V1D (Gene)
Tretinoin (Compound) causes Agranulocytosis (Side Effect)