DDInter534 DDInter1513
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome. (From Martindale, The Extra Pharmacopoeia, 30th ed, p589) Given diazepam's storied history as a commonly used and effective medication for a variety of indications, contemporary advancements in the formulation and administration of the agent include the development and US FDA approval of an auto-injectable formulation for the rapid treatment of uncontrolled seizures in 2015-2016. Combining diazepam, a proven effective therapy for acute repetitive seizures
Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Diazepam {u} (Compound) palliates {v} (Disease) multiple sclerosis
multiple sclerosis {u} (Disease) is treated by {v} (Compound) Prednisolone
Diazepam {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Prednisolone
Diazepam {u} (Compound) causes {v} (Side Effect) Hiccups
Hiccups {u} (Side Effect) is caused by {v} (Compound) Prednisolone
Diazepam {u} (Compound) resembles {v} (Compound) Alprazolam
Alprazolam {u} may cause a minor interaction that can limit clinical effects when taken with {v} Prednisolone
Diazepam {u} (Compound) resembles {v} (Compound) Oxcarbazepine
Oxcarbazepine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Prednisolone
Diazepam {u} (Compound) resembles {v} (Compound) Flurbiprofen
Flurbiprofen {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Prednisolone
Diazepam {u} (Compound) palliates {v} (Disease) multiple sclerosis
multiple sclerosis {u} (Disease) is treated by {v} (Compound) Triamcinolone
Triamcinolone {u} (Compound) resembles {v} (Compound) Prednisolone
Diazepam {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Hydrocortamate
Hydrocortamate {u} (Compound) resembles {v} (Compound) Prednisolone
Diazepam {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Progesterone
Progesterone {u} (Compound) resembles {v} (Compound) Prednisolone
Diazepam {u} (Compound) causes {v} (Side Effect) Hiccups
Hiccups {u} (Side Effect) is caused by {v} (Compound) Triamcinolone
Triamcinolone {u} (Compound) resembles {v} (Compound) Prednisolone
Diazepam (Compound) palliates multiple sclerosis (Disease) and multiple sclerosis (Disease) is treated by Prednisolone (Compound)
Diazepam (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Prednisolone (Compound)
Diazepam (Compound) causes Hiccups (Side Effect) and Hiccups (Side Effect) is caused by Prednisolone (Compound)
Diazepam (Compound) resembles Alprazolam (Compound) and Alprazolam may cause a minor interaction that can limit clinical effects when taken with Prednisolone
Diazepam (Compound) resembles Oxcarbazepine (Compound) and Oxcarbazepine may cause a moderate interaction that could exacerbate diseases when taken with Prednisolone
Diazepam (Compound) resembles Flurbiprofen (Compound) and Flurbiprofen may cause a moderate interaction that could exacerbate diseases when taken with Prednisolone
Diazepam (Compound) palliates multiple sclerosis (Disease) and multiple sclerosis (Disease) is treated by Triamcinolone (Compound) and Triamcinolone (Compound) resembles Prednisolone (Compound)
Diazepam (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Hydrocortamate (Compound) and Hydrocortamate (Compound) resembles Prednisolone (Compound)
Diazepam (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Progesterone (Compound) and Progesterone (Compound) resembles Prednisolone (Compound)
Diazepam (Compound) causes Hiccups (Side Effect) and Hiccups (Side Effect) is caused by Triamcinolone (Compound) and Triamcinolone (Compound) resembles Prednisolone (Compound)