DDInter1158 DDInter957
An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease. Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical agent. Throughout the late seventies and the eighties, important research initiatives developed stable mesalazine formulations like the eudragit-S coating of Asacol brand mesalazine and the Pentasa brand's encapsulation of mesalazine within microgranules. In the present day, contemporary research regarding novel methods to stabilize mesalazine continues and interest in the agent's capacity to decrease inflammatory activity and subsequently potentially reduce the risk of colorectal cancer in conditions like ulcerative colitis is maintained.[A174019,A174022]
Iodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.
Mesalazine {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Mesalazine {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Diatrizoate
Diatrizoate {u} (Compound) resembles {v} (Compound) Iodipamide
Mesalazine {u} (Compound) resembles {v} (Compound) Salicylic acid
Salicylic acid {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Mesalazine {u} (Compound) resembles {v} (Compound) Salicylic acid
Salicylic acid {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Mesalazine {u} (Compound) treats {v} (Disease) ulcerative colitis
ulcerative colitis {u} (Disease) is associated with {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Mesalazine {u} (Compound) downregulates {v} (Gene) MRPS2
MRPS2 {u} (Gene) is regulated by {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Mesalazine {u} (Compound) binds {v} (Gene) CHUK
CHUK {u} (Gene) is regulated by {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Mesalazine {u} (Compound) downregulates {v} (Gene) TERF2IP
TERF2IP {u} (Gene) regulates {v} (Gene) GRB7
GRB7 {u} (Gene) is downregulated by {v} (Compound) Iodipamide
Mesalazine {u} (Compound) downregulates {v} (Gene) TERF2IP
TERF2IP {u} (Gene) is regulated by {v} (Gene) NVL
NVL {u} (Gene) is downregulated by {v} (Compound) Iodipamide
Mesalazine {u} (Compound) upregulates {v} (Gene) MYLK
MYLK {u} (Gene) is regulated by {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Mesalazine (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Iodipamide (Compound)
Mesalazine (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Diatrizoate (Compound) and Diatrizoate (Compound) resembles Iodipamide (Compound)
Mesalazine (Compound) resembles Salicylic acid (Compound) and Salicylic acid (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Mesalazine (Compound) resembles Salicylic acid (Compound) and Salicylic acid (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Iodipamide (Compound)
Mesalazine (Compound) treats ulcerative colitis (Disease) and ulcerative colitis (Disease) is associated with ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Mesalazine (Compound) downregulates MRPS2 (Gene) and MRPS2 (Gene) is regulated by ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Mesalazine (Compound) binds CHUK (Gene) and CHUK (Gene) is regulated by ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Mesalazine (Compound) downregulates TERF2IP (Gene) and TERF2IP (Gene) regulates GRB7 (Gene) and GRB7 (Gene) is downregulated by Iodipamide (Compound)
Mesalazine (Compound) downregulates TERF2IP (Gene) and TERF2IP (Gene) is regulated by NVL (Gene) and NVL (Gene) is downregulated by Iodipamide (Compound)
Mesalazine (Compound) upregulates MYLK (Gene) and MYLK (Gene) is regulated by ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)