DDInter192 DDInter1544
A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. It is no longer marketed in the United States, as it has been implicated in causing ventricular arrhythmias (ie. Torsade de pointes).
Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties. The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies. Prucalopride was developed by Shire Development LLC and approved for use in Europe in 2009, in Canada on December 7, 2011 and by the FDA on December 17, 2018.
Bepridil {u} (Compound) resembles {v} (Compound) Diphenidol
Bepridil {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Diphenhydramine
Bepridil {u} (Compound) resembles {v} (Compound) Fentanyl
Bepridil {u} (Compound) treats {v} (Disease) hypertension
Bepridil {u} (Compound) binds {v} (Gene) CACNA1D
Bepridil {u} (Compound) causes {v} (Side Effect) Insomnia
Bepridil {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metronidazole
Bepridil {u} may cause a minor interaction that can limit clinical effects when taken with {v} Naloxegol
Bepridil {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Calcium glubionate anhydrous
Bepridil {u} may lead to a major life threatening interaction when taken with {v} Eliglustat
Bepridil (Compound) resembles Diphenidol (Compound)
Bepridil may cause a moderate interaction that could exacerbate diseases when taken with Diphenhydramine
Bepridil (Compound) resembles Fentanyl (Compound)
Bepridil (Compound) treats hypertension (Disease)
Bepridil (Compound) binds CACNA1D (Gene)
Bepridil (Compound) causes Insomnia (Side Effect)
Bepridil may cause a minor interaction that can limit clinical effects when taken with Metronidazole
Bepridil may cause a minor interaction that can limit clinical effects when taken with Naloxegol
Bepridil may cause a moderate interaction that could exacerbate diseases when taken with Calcium glubionate anhydrous
Bepridil may lead to a major life threatening interaction when taken with Eliglustat