DDInter458 DDInter958
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus _Beauveria nivea_. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents.
Cyclosporine {u} (Compound) upregulates {v} (Gene) XBP1
XBP1 {u} (Gene) is upregulated by {v} (Compound) Iodixanol
Cyclosporine {u} (Compound) downregulates {v} (Gene) CCDC86
CCDC86 {u} (Gene) is downregulated by {v} (Compound) Iodixanol
Cyclosporine {u} (Compound) causes {v} (Side Effect) Vertigo
Vertigo {u} (Side Effect) is caused by {v} (Compound) Iodixanol
Cyclosporine {u} (Compound) upregulates {v} (Gene) XBP1
XBP1 {u} (Gene) regulates {v} (Gene) BAMBI
BAMBI {u} (Gene) is upregulated by {v} (Compound) Iodixanol
Cyclosporine {u} (Compound) downregulates {v} (Gene) CCDC86
CCDC86 {u} (Gene) is regulated by {v} (Gene) CDK6
CDK6 {u} (Gene) is upregulated by {v} (Compound) Iodixanol
Cyclosporine {u} (Compound) downregulates {v} (Gene) ITGAE
ITGAE {u} (Gene) is downregulated by {v} (Compound) Iohexol
Iohexol {u} (Compound) resembles {v} (Compound) Iodixanol
Cyclosporine {u} (Compound) causes {v} (Side Effect) Vertigo
Vertigo {u} (Side Effect) is caused by {v} (Compound) Polythiazide
Polythiazide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iodixanol
Cyclosporine {u} (Compound) causes {v} (Side Effect) Dyspepsia
Dyspepsia {u} (Side Effect) is caused by {v} (Compound) Diclofenamide
Diclofenamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iodixanol
Cyclosporine {u} (Compound) causes {v} (Side Effect) Toxicity to various agents
Toxicity to various agents {u} (Side Effect) is caused by {v} (Compound) Iohexol
Iohexol {u} (Compound) resembles {v} (Compound) Iodixanol
Cyclosporine {u} (Compound) upregulates {v} (Gene) XBP1
XBP1 {u} (Gene) is regulated by {v} (Gene) ITGAE
ITGAE {u} (Gene) is downregulated by {v} (Compound) Iodixanol
Cyclosporine (Compound) upregulates XBP1 (Gene) and XBP1 (Gene) is upregulated by Iodixanol (Compound)
Cyclosporine (Compound) downregulates CCDC86 (Gene) and CCDC86 (Gene) is downregulated by Iodixanol (Compound)
Cyclosporine (Compound) causes Vertigo (Side Effect) and Vertigo (Side Effect) is caused by Iodixanol (Compound)
Cyclosporine (Compound) upregulates XBP1 (Gene) and XBP1 (Gene) regulates BAMBI (Gene) and BAMBI (Gene) is upregulated by Iodixanol (Compound)
Cyclosporine (Compound) downregulates CCDC86 (Gene) and CCDC86 (Gene) is regulated by CDK6 (Gene) and CDK6 (Gene) is upregulated by Iodixanol (Compound)
Cyclosporine (Compound) downregulates ITGAE (Gene) and ITGAE (Gene) is downregulated by Iohexol (Compound) and Iohexol (Compound) resembles Iodixanol (Compound)
Cyclosporine (Compound) causes Vertigo (Side Effect) and Vertigo (Side Effect) is caused by Polythiazide (Compound) and Polythiazide may cause a moderate interaction that could exacerbate diseases when taken with Iodixanol
Cyclosporine (Compound) causes Dyspepsia (Side Effect) and Dyspepsia (Side Effect) is caused by Diclofenamide (Compound) and Diclofenamide may cause a moderate interaction that could exacerbate diseases when taken with Iodixanol
Cyclosporine (Compound) causes Toxicity to various agents (Side Effect) and Toxicity to various agents (Side Effect) is caused by Iohexol (Compound) and Iohexol (Compound) resembles Iodixanol (Compound)
Cyclosporine (Compound) upregulates XBP1 (Gene) and XBP1 (Gene) is regulated by ITGAE (Gene) and ITGAE (Gene) is downregulated by Iodixanol (Compound)