DDInter571 DDInter1627
A meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine. Its unesterified metabolite difenoxin has similar properties and is used similarly. It has little or no analgesic activity. This medication is classified as a Schedule V under the Controlled Substances Act by the Food and Drug Administration (FDA) and the DEA in the United States when used in preparations. When diphenoxylate is used alone, it is classified as a Schedule II.
Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. Clinical trials suggest its efficacy in the treatment of partial seizures.
Diphenoxylate {u} (Compound) resembles {v} (Compound) Methadone
Methadone {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Rufinamide
Diphenoxylate {u} (Compound) resembles {v} (Compound) Sulfinpyrazone
Sulfinpyrazone {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Rufinamide
Diphenoxylate {u} (Compound) resembles {v} (Compound) Methadone
Methadone {u} (Compound) causes {v} (Side Effect) Rash
Rash {u} (Side Effect) is caused by {v} (Compound) Rufinamide
Diphenoxylate {u} (Compound) resembles {v} (Compound) Darifenacin
Darifenacin {u} (Compound) causes {v} (Side Effect) Mental disorder
Mental disorder {u} (Side Effect) is caused by {v} (Compound) Rufinamide
Diphenoxylate {u} (Compound) binds {v} (Gene) OPRM1
OPRM1 {u} (Gene) is associated with {v} (Disease) epilepsy syndrome
epilepsy syndrome {u} (Disease) is treated by {v} (Compound) Rufinamide
Diphenoxylate {u} (Compound) downregulates {v} (Gene) HIST1H2BK
HIST1H2BK {u} (Gene) is regulated by {v} (Gene) CES1
CES1 {u} (Gene) is bound by {v} (Compound) Rufinamide
Diphenoxylate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ketamine
Ketamine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Rufinamide
Diphenoxylate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Droperidol
Droperidol {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Rufinamide
Diphenoxylate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ketamine
Ketamine {u} (Compound) causes {v} (Side Effect) Rash
Rash {u} (Side Effect) is caused by {v} (Compound) Rufinamide
Diphenoxylate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenobarbital
Phenobarbital {u} (Compound) treats {v} (Disease) epilepsy syndrome
epilepsy syndrome {u} (Disease) is treated by {v} (Compound) Rufinamide
Diphenoxylate (Compound) resembles Methadone (Compound) and Methadone (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Rufinamide (Compound)
Diphenoxylate (Compound) resembles Sulfinpyrazone (Compound) and Sulfinpyrazone (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Rufinamide (Compound)
Diphenoxylate (Compound) resembles Methadone (Compound) and Methadone (Compound) causes Rash (Side Effect) and Rash (Side Effect) is caused by Rufinamide (Compound)
Diphenoxylate (Compound) resembles Darifenacin (Compound) and Darifenacin (Compound) causes Mental disorder (Side Effect) and Mental disorder (Side Effect) is caused by Rufinamide (Compound)
Diphenoxylate (Compound) binds OPRM1 (Gene) and OPRM1 (Gene) is associated with epilepsy syndrome (Disease) and epilepsy syndrome (Disease) is treated by Rufinamide (Compound)
Diphenoxylate (Compound) downregulates HIST1H2BK (Gene) and HIST1H2BK (Gene) is regulated by CES1 (Gene) and CES1 (Gene) is bound by Rufinamide (Compound)
Diphenoxylate may cause a moderate interaction that could exacerbate diseases when taken with Ketamine and Ketamine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Rufinamide (Compound)
Diphenoxylate may cause a moderate interaction that could exacerbate diseases when taken with Droperidol and Droperidol (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Rufinamide (Compound)
Diphenoxylate may cause a moderate interaction that could exacerbate diseases when taken with Ketamine and Ketamine (Compound) causes Rash (Side Effect) and Rash (Side Effect) is caused by Rufinamide (Compound)
Diphenoxylate may cause a moderate interaction that could exacerbate diseases when taken with Phenobarbital and Phenobarbital (Compound) treats epilepsy syndrome (Disease) and epilepsy syndrome (Disease) is treated by Rufinamide (Compound)