DDInter298 DDInter666
Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma. Early clinical studies of carboplatin were performed in 1982. Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.
Eribulin is a microtubule inhibitor indicated for the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic disease. Eribulin was isolated from the marine sponge Halichondria okadai. Eribulin is also being investigated for use in the treatment of advanced solid tumors .
Carboplatin {u} (Compound) treats {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Eribulin
Carboplatin {u} (Compound) treats {v} (Disease) esophageal cancer
esophageal cancer {u} (Disease) is treated by {v} (Compound) Cisplatin
Cisplatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eribulin
Carboplatin {u} (Compound) treats {v} (Disease) breast cancer
breast cancer {u} (Disease) is associated with {v} (Gene) TUBB3
TUBB3 {u} (Gene) is bound by {v} (Compound) Eribulin
Carboplatin {u} (Compound) treats {v} (Disease) ovarian cancer
ovarian cancer {u} (Disease) resembles {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Eribulin
Carboplatin {u} (Compound) treats {v} (Disease) bone cancer
bone cancer {u} (Disease) resembles {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Eribulin
Carboplatin {u} (Compound) binds {v} (Gene) GSTM1
GSTM1 {u} (Gene) is bound by {v} (Compound) Cisplatin
Cisplatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eribulin
Carboplatin {u} (Compound) binds {v} (Gene) GSTM1
GSTM1 {u} (Gene) is associated with {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Eribulin
Carboplatin {u} (Compound) binds {v} (Gene) SOD1
SOD1 {u} (Gene) regulates {v} (Gene) TUBB4B
TUBB4B {u} (Gene) is bound by {v} (Compound) Eribulin
Carboplatin {u} (Compound) treats {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Toremifene
Toremifene {u} may lead to a major life threatening interaction when taken with {v} Eribulin
Carboplatin {u} (Compound) binds {v} (Gene) SLC31A2
SLC31A2 {u} (Gene) is upregulated by {v} (Compound) Teniposide
Teniposide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eribulin
Carboplatin (Compound) treats breast cancer (Disease) and breast cancer (Disease) is treated by Eribulin (Compound)
Carboplatin (Compound) treats esophageal cancer (Disease) and esophageal cancer (Disease) is treated by Cisplatin (Compound) and Cisplatin may cause a moderate interaction that could exacerbate diseases when taken with Eribulin
Carboplatin (Compound) treats breast cancer (Disease) and breast cancer (Disease) is associated with TUBB3 (Gene) and TUBB3 (Gene) is bound by Eribulin (Compound)
Carboplatin (Compound) treats ovarian cancer (Disease) and ovarian cancer (Disease) resembles breast cancer (Disease) and breast cancer (Disease) is treated by Eribulin (Compound)
Carboplatin (Compound) treats bone cancer (Disease) and bone cancer (Disease) resembles breast cancer (Disease) and breast cancer (Disease) is treated by Eribulin (Compound)
Carboplatin (Compound) binds GSTM1 (Gene) and GSTM1 (Gene) is bound by Cisplatin (Compound) and Cisplatin may cause a moderate interaction that could exacerbate diseases when taken with Eribulin
Carboplatin (Compound) binds GSTM1 (Gene) and GSTM1 (Gene) is associated with breast cancer (Disease) and breast cancer (Disease) is treated by Eribulin (Compound)
Carboplatin (Compound) binds SOD1 (Gene) and SOD1 (Gene) regulates TUBB4B (Gene) and TUBB4B (Gene) is bound by Eribulin (Compound)
Carboplatin (Compound) treats breast cancer (Disease) and breast cancer (Disease) is treated by Toremifene (Compound) and Toremifene may lead to a major life threatening interaction when taken with Eribulin
Carboplatin (Compound) binds SLC31A2 (Gene) and SLC31A2 (Gene) is upregulated by Teniposide (Compound) and Teniposide may cause a moderate interaction that could exacerbate diseases when taken with Eribulin