DDInter944 DDInter576
Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated. This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced from individual alpha interferon genes.
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.
Interferon alfa-n1 {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cyclophosphamide
Cyclophosphamide {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Disulfiram
Interferon alfa-n1 {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cabazitaxel
Cabazitaxel {u} (Compound) binds {v} (Gene) CYP3A5
CYP3A5 {u} (Gene) is bound by {v} (Compound) Disulfiram
Interferon alfa-n1 {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ethambutol
Ethambutol {u} (Compound) downregulates {v} (Gene) TARBP1
TARBP1 {u} (Gene) is downregulated by {v} (Compound) Disulfiram
Interferon alfa-n1 {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ethambutol
Ethambutol {u} (Compound) causes {v} (Side Effect) Paraesthesia
Paraesthesia {u} (Side Effect) is caused by {v} (Compound) Disulfiram
Interferon alfa-n1 {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cabazitaxel
Cabazitaxel {u} (Compound) binds {v} (Gene) TUBB6
TUBB6 {u} (Gene) is upregulated by {v} (Compound) Disulfiram
Interferon alfa-n1 {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cyclophosphamide
Cyclophosphamide {u} (Compound) downregulates {v} (Gene) MTHFD2
MTHFD2 {u} (Gene) is upregulated by {v} (Compound) Disulfiram
Interferon alfa-n1 {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cyclophosphamide
Cyclophosphamide {u} (Compound) downregulates {v} (Gene) CNDP2
CNDP2 {u} (Gene) is downregulated by {v} (Compound) Disulfiram
Interferon alfa-n1 {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Hydroxychloroquine
Hydroxychloroquine {u} (Compound) upregulates {v} (Gene) PAK1
PAK1 {u} (Gene) is upregulated by {v} (Compound) Disulfiram
Interferon alfa-n1 {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cyclophosphamide
Cyclophosphamide {u} (Compound) causes {v} (Side Effect) Paraesthesia
Paraesthesia {u} (Side Effect) is caused by {v} (Compound) Disulfiram
Interferon alfa-n1 {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Topotecan
Topotecan {u} (Compound) downregulates {v} (Gene) FHL2
FHL2 {u} (Gene) is upregulated by {v} (Compound) Disulfiram
Interferon alfa-n1 may cause a minor interaction that can limit clinical effects when taken with Cyclophosphamide and Cyclophosphamide (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Disulfiram (Compound)
Interferon alfa-n1 may cause a moderate interaction that could exacerbate diseases when taken with Cabazitaxel and Cabazitaxel (Compound) binds CYP3A5 (Gene) and CYP3A5 (Gene) is bound by Disulfiram (Compound)
Interferon alfa-n1 may cause a moderate interaction that could exacerbate diseases when taken with Ethambutol and Ethambutol (Compound) downregulates TARBP1 (Gene) and TARBP1 (Gene) is downregulated by Disulfiram (Compound)
Interferon alfa-n1 may cause a moderate interaction that could exacerbate diseases when taken with Ethambutol and Ethambutol (Compound) causes Paraesthesia (Side Effect) and Paraesthesia (Side Effect) is caused by Disulfiram (Compound)
Interferon alfa-n1 may cause a moderate interaction that could exacerbate diseases when taken with Cabazitaxel and Cabazitaxel (Compound) binds TUBB6 (Gene) and TUBB6 (Gene) is upregulated by Disulfiram (Compound)
Interferon alfa-n1 may cause a minor interaction that can limit clinical effects when taken with Cyclophosphamide and Cyclophosphamide (Compound) downregulates MTHFD2 (Gene) and MTHFD2 (Gene) is upregulated by Disulfiram (Compound)
Interferon alfa-n1 may cause a minor interaction that can limit clinical effects when taken with Cyclophosphamide and Cyclophosphamide (Compound) downregulates CNDP2 (Gene) and CNDP2 (Gene) is downregulated by Disulfiram (Compound)
Interferon alfa-n1 may cause a moderate interaction that could exacerbate diseases when taken with Hydroxychloroquine and Hydroxychloroquine (Compound) upregulates PAK1 (Gene) and PAK1 (Gene) is upregulated by Disulfiram (Compound)
Interferon alfa-n1 may cause a minor interaction that can limit clinical effects when taken with Cyclophosphamide and Cyclophosphamide (Compound) causes Paraesthesia (Side Effect) and Paraesthesia (Side Effect) is caused by Disulfiram (Compound)
Interferon alfa-n1 may cause a moderate interaction that could exacerbate diseases when taken with Topotecan and Topotecan (Compound) downregulates FHL2 (Gene) and FHL2 (Gene) is upregulated by Disulfiram (Compound)