DDInter1031 DDInter1118
Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients. Treatment options for chronic Hepatitis C have advanced significantly since 2011, with the development of Direct Acting Antivirals (DAAs) such as ledipasvir. More specifically, ledipasvir is an inhibitor of the Hepatitis C Virus (HCV) Non-Structural Protein 5A (NS5A), which is required for viral RNA replication and assembly of HCV virions. Although its exact mechanism of action is unknown, it is postulated to prevent hyperphosphorylation of NS5A which is required
Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used commercially as a fire retardant. It can also be used topically as a deodorant or for the relief of canker sores (aphthous ulcers).
Magnesium hydroxide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Quazepam
Magnesium hydroxide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Diclofenamide
Magnesium hydroxide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Deutetrabenazine
Magnesium hydroxide {u} may lead to a major life threatening interaction when taken with {v} Erdafitinib
Magnesium hydroxide {u} may lead to a major life threatening interaction when taken with {v} Tolevamer
Magnesium hydroxide may cause a minor interaction that can limit clinical effects when taken with Quazepam
Magnesium hydroxide may cause a moderate interaction that could exacerbate diseases when taken with Diclofenamide
Magnesium hydroxide may cause a moderate interaction that could exacerbate diseases when taken with Deutetrabenazine
Magnesium hydroxide may lead to a major life threatening interaction when taken with Erdafitinib
Magnesium hydroxide may lead to a major life threatening interaction when taken with Tolevamer