DDInter405 DDInter434
Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed. It is not known if the drug extends life expectancy. Its potential use in acute myeloid leukaemia (AML) and juvenile myelomonocytic leukaemia (JMML) has been investigated.
Colistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms. Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aeruginosa.
Clofarabine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Bacitracin
Bacitracin {u} (Compound) resembles {v} (Compound) Colistimethate
Clofarabine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Polymyxin B
Polymyxin B {u} (Compound) resembles {v} (Compound) Colistimethate
Clofarabine {u} (Compound) causes {v} (Side Effect) Mental disorder
Mental disorder {u} (Side Effect) is caused by {v} (Compound) Colistimethate
Clofarabine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Bacitracin
Bacitracin {u} (Compound) resembles {v} (Compound) Colistin
Colistin {u} (Compound) resembles {v} (Compound) Colistimethate
Clofarabine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Polymyxin B
Polymyxin B {u} (Compound) resembles {v} (Compound) Bacitracin
Bacitracin {u} (Compound) resembles {v} (Compound) Colistimethate
Clofarabine {u} (Compound) causes {v} (Side Effect) Headache
Headache {u} (Side Effect) is caused by {v} (Compound) Polymyxin B
Polymyxin B {u} (Compound) resembles {v} (Compound) Colistimethate
Clofarabine {u} (Compound) causes {v} (Side Effect) Dermatitis
Dermatitis {u} (Side Effect) is caused by {v} (Compound) Bacitracin
Bacitracin {u} (Compound) resembles {v} (Compound) Colistimethate
Clofarabine {u} (Compound) upregulates {v} (Gene) PTGS2
PTGS2 {u} (Gene) is upregulated by {v} (Compound) Bacitracin
Bacitracin {u} (Compound) resembles {v} (Compound) Colistimethate
Clofarabine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Polymyxin B
Polymyxin B {u} (Compound) resembles {v} (Compound) Colistin
Colistin {u} (Compound) resembles {v} (Compound) Colistimethate
Clofarabine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Bacitracin
Bacitracin {u} (Compound) causes {v} (Side Effect) Dermatitis
Dermatitis {u} (Side Effect) is caused by {v} (Compound) Colistimethate
Clofarabine may cause a moderate interaction that could exacerbate diseases when taken with Bacitracin and Bacitracin (Compound) resembles Colistimethate (Compound)
Clofarabine may cause a moderate interaction that could exacerbate diseases when taken with Polymyxin B and Polymyxin B (Compound) resembles Colistimethate (Compound)
Clofarabine (Compound) causes Mental disorder (Side Effect) and Mental disorder (Side Effect) is caused by Colistimethate (Compound)
Clofarabine may cause a moderate interaction that could exacerbate diseases when taken with Bacitracin and Bacitracin (Compound) resembles Colistin (Compound) and Colistin (Compound) resembles Colistimethate (Compound)
Clofarabine may cause a moderate interaction that could exacerbate diseases when taken with Polymyxin B and Polymyxin B (Compound) resembles Bacitracin (Compound) and Bacitracin (Compound) resembles Colistimethate (Compound)
Clofarabine (Compound) causes Headache (Side Effect) and Headache (Side Effect) is caused by Polymyxin B (Compound) and Polymyxin B (Compound) resembles Colistimethate (Compound)
Clofarabine (Compound) causes Dermatitis (Side Effect) and Dermatitis (Side Effect) is caused by Bacitracin (Compound) and Bacitracin (Compound) resembles Colistimethate (Compound)
Clofarabine (Compound) upregulates PTGS2 (Gene) and PTGS2 (Gene) is upregulated by Bacitracin (Compound) and Bacitracin (Compound) resembles Colistimethate (Compound)
Clofarabine may cause a moderate interaction that could exacerbate diseases when taken with Polymyxin B and Polymyxin B (Compound) resembles Colistin (Compound) and Colistin (Compound) resembles Colistimethate (Compound)
Clofarabine may cause a moderate interaction that could exacerbate diseases when taken with Bacitracin and Bacitracin (Compound) causes Dermatitis (Side Effect) and Dermatitis (Side Effect) is caused by Colistimethate (Compound)