DDInter790 DDInter120
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of water from the body. Furosemide has a fast onset and short duration of action and has been used safely and effectively in both pediatric and adult patients. The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential. In addition to oral formulations, the solution for intravenous and intramuscular administration is also available, which is typically limited to patients who are unable to take oral medication or for patients in emergency clinical situations.
Arsenic trioxide is a chemotherapeutic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents. It is suspected that arsenic trisulfide induces cancer cells to undergo apoptosis. In general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous adverse effects. The enzyme thioredoxin reductase has recently been identified as a target for arsenic trioxide.
Furosemide {u} (Compound) binds {v} (Gene) ABCC2
ABCC2 {u} (Gene) is bound by {v} (Compound) Arsenic trioxide
Furosemide {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} may lead to a major life threatening interaction when taken with {v} Arsenic trioxide
Furosemide {u} (Compound) binds {v} (Gene) ABCC2
ABCC2 {u} (Gene) is bound by {v} (Compound) Daunorubicin
Daunorubicin {u} may lead to a major life threatening interaction when taken with {v} Arsenic trioxide
Furosemide {u} (Compound) resembles {v} (Compound) Bumetanide
Bumetanide {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} may lead to a major life threatening interaction when taken with {v} Arsenic trioxide
Furosemide {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Arsenic trioxide
Furosemide {u} (Compound) treats {v} (Disease) coronary artery disease
coronary artery disease {u} (Disease) is associated with {v} (Gene) CCND1
CCND1 {u} (Gene) is bound by {v} (Compound) Arsenic trioxide
Furosemide {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Magnesium citrate
Magnesium citrate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Arsenic trioxide
Furosemide {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Chlorothiazide
Chlorothiazide {u} may lead to a major life threatening interaction when taken with {v} Arsenic trioxide
Furosemide {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Formoterol
Formoterol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Arsenic trioxide
Furosemide {u} (Compound) binds {v} (Gene) ABCC2
ABCC2 {u} (Gene) is bound by {v} (Compound) Sparfloxacin
Sparfloxacin {u} may lead to a major life threatening interaction when taken with {v} Arsenic trioxide
Furosemide (Compound) binds ABCC2 (Gene) and ABCC2 (Gene) is bound by Arsenic trioxide (Compound)
Furosemide (Compound) resembles Indapamide (Compound) and Indapamide may lead to a major life threatening interaction when taken with Arsenic trioxide
Furosemide (Compound) binds ABCC2 (Gene) and ABCC2 (Gene) is bound by Daunorubicin (Compound) and Daunorubicin may lead to a major life threatening interaction when taken with Arsenic trioxide
Furosemide (Compound) resembles Bumetanide (Compound) and Bumetanide (Compound) resembles Indapamide (Compound) and Indapamide may lead to a major life threatening interaction when taken with Arsenic trioxide
Furosemide (Compound) resembles Indapamide (Compound) and Indapamide (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Arsenic trioxide (Compound)
Furosemide (Compound) treats coronary artery disease (Disease) and coronary artery disease (Disease) is associated with CCND1 (Gene) and CCND1 (Gene) is bound by Arsenic trioxide (Compound)
Furosemide (Compound) resembles Indapamide (Compound) and Indapamide may cause a moderate interaction that could exacerbate diseases when taken with Magnesium citrate and Magnesium citrate may cause a moderate interaction that could exacerbate diseases when taken with Arsenic trioxide
Furosemide (Compound) treats hypertension (Disease) and hypertension (Disease) is treated by Chlorothiazide (Compound) and Chlorothiazide may lead to a major life threatening interaction when taken with Arsenic trioxide
Furosemide (Compound) resembles Indapamide (Compound) and Indapamide may cause a moderate interaction that could exacerbate diseases when taken with Formoterol and Formoterol may cause a moderate interaction that could exacerbate diseases when taken with Arsenic trioxide
Furosemide (Compound) binds ABCC2 (Gene) and ABCC2 (Gene) is bound by Sparfloxacin (Compound) and Sparfloxacin may lead to a major life threatening interaction when taken with Arsenic trioxide