DDInter948 DDInter900
Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and this drug was first launched against rheumatoid arthritis in the UK in 1969 and USA in 1974. It was the first available over-the-counter NSAID. On the available products, ibuprofen is administered as a racemic mixture. Once administered, the R-enantiomer undergoes extensive interconversion to the S-enantiomer _in vivo_ by the activity of the alpha-methylacyl-CoA racemase. In particular, it is generally proposed that the S-enantiomer is capable of eliciting stronger pharmacological activity than the R-enantiomer.
Ibuprofen {u} (Compound) resembles {v} (Compound) Carprofen
Ibuprofen {u} (Compound) resembles {v} (Compound) Metyrosine
Ibuprofen {u} (Compound) binds {v} (Gene) SLCO2B1
Ibuprofen {u} (Compound) palliates {v} (Disease) osteoarthritis
Ibuprofen {u} (Compound) is included by {v} (Pharmacologic Class) Nonsteroidal Anti-inflammatory Compounds
Ibuprofen {u} (Compound) causes {v} (Side Effect) Urethral disorder
Ibuprofen {u} may cause a minor interaction that can limit clinical effects when taken with {v} Clove
Ibuprofen {u} may cause a minor interaction that can limit clinical effects when taken with {v} Tacrine
Ibuprofen {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indomethacin
Ibuprofen {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Bedaquiline
Ibuprofen (Compound) resembles Carprofen (Compound)
Ibuprofen (Compound) resembles Metyrosine (Compound)
Ibuprofen (Compound) binds SLCO2B1 (Gene)
Ibuprofen (Compound) palliates osteoarthritis (Disease)
Ibuprofen (Compound) is included by Nonsteroidal Anti-inflammatory Compounds (Pharmacologic Class)
Ibuprofen (Compound) causes Urethral disorder (Side Effect)
Ibuprofen may cause a minor interaction that can limit clinical effects when taken with Clove
Ibuprofen may cause a minor interaction that can limit clinical effects when taken with Tacrine
Ibuprofen may cause a moderate interaction that could exacerbate diseases when taken with Indomethacin
Ibuprofen may cause a moderate interaction that could exacerbate diseases when taken with Bedaquiline