DDInter1545 DDInter1376
Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described in dogs in 1927.
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26, 2020.[L12573,L12582] The US approval was followed by the approval in Canada on October 2, 2020. In November 2021, ozanimod was also approved by the European Commission for the treatment of adults with relapsing remitting multiple sclerosis.[L39377,L39382] MS is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Inflammatory bowel disease also a chronic inflammatory condition and can cause persistent abdominal pain, diarrhea, bloody stools, and vomiting. In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard in MS therapy. Studies involving patients with inflammatory bowel disease have also shown promising results.[A189318,A189342]
Pseudoephedrine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phentermine
Pseudoephedrine {u} (Compound) resembles {v} (Compound) Mephentermine
Pseudoephedrine {u} (Compound) resembles {v} (Compound) Bethanidine
Pseudoephedrine {u} (Compound) binds {v} (Gene) ADRA1A
Pseudoephedrine {u} (Compound) palliates {v} (Disease) allergic rhinitis
Pseudoephedrine {u} (Compound) is included by {v} (Pharmacologic Class) Adrenergic alpha-Agonists
Pseudoephedrine {u} (Compound) downregulates {v} (Gene) COG2
Pseudoephedrine {u} (Compound) causes {v} (Side Effect) Chest pain
Pseudoephedrine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ammonium chloride
Pseudoephedrine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Methionine
Pseudoephedrine may cause a moderate interaction that could exacerbate diseases when taken with Phentermine
Pseudoephedrine (Compound) resembles Mephentermine (Compound)
Pseudoephedrine (Compound) resembles Bethanidine (Compound)
Pseudoephedrine (Compound) binds ADRA1A (Gene)
Pseudoephedrine (Compound) palliates allergic rhinitis (Disease)
Pseudoephedrine (Compound) is included by Adrenergic alpha-Agonists (Pharmacologic Class)
Pseudoephedrine (Compound) downregulates COG2 (Gene)
Pseudoephedrine (Compound) causes Chest pain (Side Effect)
Pseudoephedrine may cause a minor interaction that can limit clinical effects when taken with Ammonium chloride
Pseudoephedrine may cause a minor interaction that can limit clinical effects when taken with Methionine