DDInter130 DDInter278
Atenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. Sir James Black, a Scottish pharmacologist, pioneered the use of beta-blockers for the management of angina pectoris in 1958 for which he received the Nobel Prize. Beta-blockers quickly became popular in clinical use and where subsequently investigated for use in myocardial infarction, arrhythmias, and hypertension during the 1960s. Later they continued to be investigated for use in heart failure throughout the 1970-1980s. Atenolol itself was developed early on in this history by Alvogen Malta under the trade name Tenormin and received FDA approval in September, 1981.[label] Despite being one of the most widely prescribed beta blockers, evidence suggests atenolol may not significantly reduce mortality, and only modestly reduce the risk of cardiovascular disease in patients with hypertension.[A235850,A235855] A Cochrane review
Calcium lactate is a salt that consists of two lactate anions for each calcium cation (Ca2+). It is prepared commercially by the neutralization of lactic acid with calcium carbonate or calcium hydroxide. Approved by the FDA as a direct food substance affirmed as generally recognized as safe, calcium lactate is used as a firming agent, flavoring agent, leavening agent, stabilizer, and thickener . Calcium lactate is also found in daily dietary supplements as a source of calcium. It is also available in various hydrate forms, where calcium lactate pentahydrate is the most common.
Atenolol {u} (Compound) resembles {v} (Compound) Oxprenolol
Atenolol {u} (Compound) resembles {v} (Compound) Chlorphenesin
Atenolol {u} (Compound) binds {v} (Gene) ADRB2
Atenolol {u} (Compound) upregulates {v} (Gene) UBQLN2
Atenolol {u} (Compound) causes {v} (Side Effect) Dry mouth
Atenolol (Compound) resembles Oxprenolol (Compound)
Atenolol (Compound) resembles Chlorphenesin (Compound)
Atenolol (Compound) binds ADRB2 (Gene)
Atenolol (Compound) upregulates UBQLN2 (Gene)
Atenolol (Compound) causes Dry mouth (Side Effect)