DDInter350 DDInter485
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.
Chlorambucil {u} (Compound) treats {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is treated by {v} (Compound) Daunorubicin
Chlorambucil {u} (Compound) upregulates {v} (Gene) GPC1
GPC1 {u} (Gene) is upregulated by {v} (Compound) Daunorubicin
Chlorambucil {u} (Compound) downregulates {v} (Gene) AURKA
AURKA {u} (Gene) is downregulated by {v} (Compound) Daunorubicin
Chlorambucil {u} (Compound) upregulates {v} (Gene) FHL2
FHL2 {u} (Gene) is downregulated by {v} (Compound) Daunorubicin
Chlorambucil {u} (Compound) causes {v} (Side Effect) Abdominal pain
Abdominal pain {u} (Side Effect) is caused by {v} (Compound) Daunorubicin
Chlorambucil {u} (Compound) resembles {v} (Compound) Melphalan
Melphalan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Daunorubicin
Chlorambucil {u} (Compound) treats {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is treated by {v} (Compound) Doxorubicin
Doxorubicin {u} (Compound) resembles {v} (Compound) Daunorubicin
Chlorambucil {u} (Compound) upregulates {v} (Gene) GPC1
GPC1 {u} (Gene) is upregulated by {v} (Compound) Doxorubicin
Doxorubicin {u} (Compound) resembles {v} (Compound) Daunorubicin
Chlorambucil {u} (Compound) downregulates {v} (Gene) AURKA
AURKA {u} (Gene) is bound by {v} (Compound) and {u} (Gene) is downregulated by {v} (Compound) Doxorubicin
Doxorubicin {u} (Compound) resembles {v} (Compound) Daunorubicin
Chlorambucil {u} (Compound) downregulates {v} (Gene) CENPA
CENPA {u} (Gene) is downregulated by {v} (Compound) Doxorubicin
Doxorubicin {u} (Compound) resembles {v} (Compound) Daunorubicin
Chlorambucil (Compound) treats hematologic cancer (Disease) and hematologic cancer (Disease) is treated by Daunorubicin (Compound)
Chlorambucil (Compound) upregulates GPC1 (Gene) and GPC1 (Gene) is upregulated by Daunorubicin (Compound)
Chlorambucil (Compound) downregulates AURKA (Gene) and AURKA (Gene) is downregulated by Daunorubicin (Compound)
Chlorambucil (Compound) upregulates FHL2 (Gene) and FHL2 (Gene) is downregulated by Daunorubicin (Compound)
Chlorambucil (Compound) causes Abdominal pain (Side Effect) and Abdominal pain (Side Effect) is caused by Daunorubicin (Compound)
Chlorambucil (Compound) resembles Melphalan (Compound) and Melphalan may cause a moderate interaction that could exacerbate diseases when taken with Daunorubicin
Chlorambucil (Compound) treats hematologic cancer (Disease) and hematologic cancer (Disease) is treated by Doxorubicin (Compound) and Doxorubicin (Compound) resembles Daunorubicin (Compound)
Chlorambucil (Compound) upregulates GPC1 (Gene) and GPC1 (Gene) is upregulated by Doxorubicin (Compound) and Doxorubicin (Compound) resembles Daunorubicin (Compound)
Chlorambucil (Compound) downregulates AURKA (Gene) and AURKA (Gene) is bound by Doxorubicin (Compound) and AURKA (Gene) is downregulated by Doxorubicin (Compound) and Doxorubicin (Compound) resembles Daunorubicin (Compound)
Chlorambucil (Compound) downregulates CENPA (Gene) and CENPA (Gene) is downregulated by Doxorubicin (Compound) and Doxorubicin (Compound) resembles Daunorubicin (Compound)