DDInter885 DDInter1676
Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. Hydrocortisone was granted FDA approval on 5 August 1952.
Siponimod, also known as _Mayzent_, by Novartis, is a new drug formulated for the management of Multiple Sclerosis (MS). It was approved by the FDA on March 26, 2019 and by Health Canada on February 20, 2020. This drug is considered a _sphingosine-1-phosphate (S1P) receptor modulator_ and is thought to play a role in suppressing the central nervous system inflammation that is associated with MS [FDA label]. Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system that is chronic and inflammatory, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of life. Symptoms may include but are not limited to fatigue, gait changes, bowel or bladder dysfunction, abnormal muscle twitching, vision disturbance, and depressing or mood swings. MS is one of the most common causes of neurological disability in young adults and is found to occur more frequently in women than in men.[A176474,L5792]
Hydrocortisone {u} (Compound) resembles {v} (Compound) Loteprednol
Hydrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eplerenone
Hydrocortisone {u} (Compound) resembles {v} (Compound) Fludrocortisone
Hydrocortisone {u} (Compound) treats {v} (Disease) gout
Hydrocortisone {u} (Compound) binds {v} (Gene) CYP11B1
Hydrocortisone {u} (Compound) upregulates {v} (Gene) PRKCD
Hydrocortisone {u} (Compound) palliates {v} (Disease) prostate cancer
Hydrocortisone {u} (Compound) is included by {v} (Pharmacologic Class) Corticosteroid Hormone Receptor Agonists
Hydrocortisone {u} (Compound) downregulates {v} (Gene) AMIGO2
Hydrocortisone {u} (Compound) causes {v} (Side Effect) Papilloedema
Hydrocortisone (Compound) resembles Loteprednol (Compound)
Hydrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Eplerenone
Hydrocortisone (Compound) resembles Fludrocortisone (Compound)
Hydrocortisone (Compound) treats gout (Disease)
Hydrocortisone (Compound) binds CYP11B1 (Gene)
Hydrocortisone (Compound) upregulates PRKCD (Gene)
Hydrocortisone (Compound) palliates prostate cancer (Disease)
Hydrocortisone (Compound) is included by Corticosteroid Hormone Receptor Agonists (Pharmacologic Class)
Hydrocortisone (Compound) downregulates AMIGO2 (Gene)
Hydrocortisone (Compound) causes Papilloedema (Side Effect)