DDInter554 DDInter1180
Digoxin is one of the oldest cardiovascular medications used today. It is a common agent used to manage atrial fibrillation and the symptoms of heart failure. Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954. This drug originates from the foxglove plant, also known as the _Digitalis_ plant, studied by William Withering, an English physician and botanist in the 1780s.[A178237,A178240] Prior to this, a Welsh family, historically referred to as the _Physicians of Myddvai_, formulated drugs from this plant. They were one of the first to prescribe cardiac glycosides, according to ancient literature dating as early as the 1250s.
Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Digoxin {u} (Compound) resembles {v} (Compound) Deslanoside
Digoxin {u} (Compound) resembles {v} (Compound) Acetyldigitoxin
Digoxin {u} (Compound) binds {v} (Gene) ATP1A3
Digoxin {u} (Compound) upregulates {v} (Gene) RRN3
Digoxin {u} (Compound) palliates {v} (Disease) dilated cardiomyopathy
Digoxin {u} (Compound) is included by {v} (Pharmacologic Class) Cardiac Glycosides
Digoxin {u} (Compound) downregulates {v} (Gene) C17orf62
Digoxin {u} (Compound) causes {v} (Side Effect) Thrombocytopenia
Digoxin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium oxide
Digoxin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ticlopidine
Digoxin (Compound) resembles Deslanoside (Compound)
Digoxin (Compound) resembles Acetyldigitoxin (Compound)
Digoxin (Compound) binds ATP1A3 (Gene)
Digoxin (Compound) upregulates RRN3 (Gene)
Digoxin (Compound) palliates dilated cardiomyopathy (Disease)
Digoxin (Compound) is included by Cardiac Glycosides (Pharmacologic Class)
Digoxin (Compound) downregulates C17orf62 (Gene)
Digoxin (Compound) causes Thrombocytopenia (Side Effect)
Digoxin may cause a minor interaction that can limit clinical effects when taken with Magnesium oxide
Digoxin may cause a minor interaction that can limit clinical effects when taken with Ticlopidine