DDInter1167 DDInter1476
A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
Pirbuterol is a beta-2 adrenergic bronchodilator. In vitro studies and in vivo pharmacologic studies have demonstrated that pirbuterol has a preferential effect on beta-2 Adrenergic receptors compared with isoproterenol. While it is recognized that beta-2 adrenergic receptors are the predominant receptors in bronchial smooth muscle, data indicate that there is a population of beta-2 receptors in the human heart, existing in a concentration between 10-50%. The precise function of these receptors has not been established. The pharmacologic effects of beta adrenergic agonist drugs, including pirbuterol, are at least in proof attributable to stimulation through beta adrenergic receptors of intracellular adenyl cyclase, the enzyme which catalyzes the conversion of adenosine triphosphate (AlP) to cyclic-3† ,5†-adenosine monophosphate (c-AMP). Increased c-AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.
Methazolamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Salbutamol
Salbutamol {u} (Compound) resembles {v} (Compound) Pirbuterol
Methazolamide {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Pirbuterol
Methazolamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Salbutamol
Salbutamol {u} (Compound) resembles {v} (Compound) Bupranolol
Bupranolol {u} (Compound) resembles {v} (Compound) Pirbuterol
Methazolamide {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Terbutaline
Terbutaline {u} (Compound) resembles {v} (Compound) Pirbuterol
Methazolamide {u} (Compound) causes {v} (Side Effect) Feeling abnormal
Feeling abnormal {u} (Side Effect) is caused by {v} (Compound) Salbutamol
Salbutamol {u} (Compound) resembles {v} (Compound) Pirbuterol
Methazolamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Orciprenaline
Orciprenaline {u} (Compound) resembles {v} (Compound) Terbutaline
Terbutaline {u} (Compound) resembles {v} (Compound) Pirbuterol
Methazolamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Orciprenaline
Orciprenaline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Salbutamol
Salbutamol {u} (Compound) resembles {v} (Compound) Pirbuterol
Methazolamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Orciprenaline
Orciprenaline {u} may lead to a major life threatening interaction when taken with {v} Nadolol
Nadolol {u} (Compound) resembles {v} (Compound) Pirbuterol
Methazolamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Salbutamol
Salbutamol {u} (Compound) resembles {v} (Compound) and {u} may lead to a major life threatening interaction when taken with {v} Nadolol
Nadolol {u} (Compound) resembles {v} (Compound) Pirbuterol
Methazolamide {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Salbutamol
Salbutamol {u} (Compound) resembles {v} (Compound) Pirbuterol
Methazolamide may cause a moderate interaction that could exacerbate diseases when taken with Salbutamol and Salbutamol (Compound) resembles Pirbuterol (Compound)
Methazolamide (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Pirbuterol (Compound)
Methazolamide may cause a moderate interaction that could exacerbate diseases when taken with Salbutamol and Salbutamol (Compound) resembles Bupranolol (Compound) and Bupranolol (Compound) resembles Pirbuterol (Compound)
Methazolamide (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Terbutaline (Compound) and Terbutaline (Compound) resembles Pirbuterol (Compound)
Methazolamide (Compound) causes Feeling abnormal (Side Effect) and Feeling abnormal (Side Effect) is caused by Salbutamol (Compound) and Salbutamol (Compound) resembles Pirbuterol (Compound)
Methazolamide may cause a moderate interaction that could exacerbate diseases when taken with Orciprenaline and Orciprenaline (Compound) resembles Terbutaline (Compound) and Terbutaline (Compound) resembles Pirbuterol (Compound)
Methazolamide may cause a moderate interaction that could exacerbate diseases when taken with Orciprenaline and Orciprenaline may cause a moderate interaction that could exacerbate diseases when taken with Salbutamol and Salbutamol (Compound) resembles Pirbuterol (Compound)
Methazolamide may cause a moderate interaction that could exacerbate diseases when taken with Orciprenaline and Orciprenaline may lead to a major life threatening interaction when taken with Nadolol and Nadolol (Compound) resembles Pirbuterol (Compound)
Methazolamide may cause a moderate interaction that could exacerbate diseases when taken with Salbutamol and Salbutamol (Compound) resembles Nadolol (Compound) and Salbutamol may lead to a major life threatening interaction when taken with Nadolol and Nadolol (Compound) resembles Pirbuterol (Compound)
Methazolamide (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Salbutamol (Compound) and Salbutamol (Compound) resembles Pirbuterol (Compound)