DDInter1704 DDInter1016
Sotalol is a methanesulfonanilide developed in 1960. It was the first of the class III anti arrhythmic drugs. Sotalol was first approved as an oral tablet on 30 October 1992. A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous injection indicated for life threatening ventricular arrhythmias and maintaining normal sinus rhythm in atrial fibrillation or flutter.[Label,L6373,L6376]
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose]. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. [sucrose]). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in patients with cirrhosis.[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.
Sotalol {u} (Compound) resembles {v} (Compound) Atenolol
Sotalol {u} (Compound) binds {v} (Gene) ADRB1
Sotalol {u} (Compound) is included by {v} (Pharmacologic Class) Cardiac Rhythm Alteration
Sotalol {u} (Compound) causes {v} (Side Effect) Ache
Sotalol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Sucralfate
Sotalol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Kaolin
Sotalol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Insulin degludec
Sotalol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Thiethylperazine
Sotalol {u} may lead to a major life threatening interaction when taken with {v} Picosulfuric acid
Sotalol {u} may lead to a major life threatening interaction when taken with {v} Terfenadine
Sotalol (Compound) resembles Atenolol (Compound)
Sotalol (Compound) binds ADRB1 (Gene)
Sotalol (Compound) is included by Cardiac Rhythm Alteration (Pharmacologic Class)
Sotalol (Compound) causes Ache (Side Effect)
Sotalol may cause a minor interaction that can limit clinical effects when taken with Sucralfate
Sotalol may cause a minor interaction that can limit clinical effects when taken with Kaolin
Sotalol may cause a moderate interaction that could exacerbate diseases when taken with Insulin degludec
Sotalol may cause a moderate interaction that could exacerbate diseases when taken with Thiethylperazine
Sotalol may lead to a major life threatening interaction when taken with Picosulfuric acid
Sotalol may lead to a major life threatening interaction when taken with Terfenadine