DDInter1252 DDInter1396
Mycophenolic acid is a potent immunosuppressant agent that inhibits _de novo_ purine biosynthesis. It was derived from _Penicillium stoloniferum_, and has also shown antibacterial, antifungal and antiviral properties.. Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. This regimen can be used in place of the older anti-proliferative [azathioprine] due to its stronger immunosuppressive potency. However, mycophenolic acid treatment is more expensive and requires therapeutic drug monitoring to optimize efficacy and minimize toxicity.[A249180,A249185] Mycophenolic acid is available as enteric-coated tablets of delayed-release, in an effort to improve upper gastrointestinal adverse events by delaying mycophenolic
An oligosaccharide antibiotic produced by various streptomyces. [PubChem]
Mycophenolic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Kanamycin
Kanamycin {u} (Compound) resembles {v} (Compound) Paromomycin
Mycophenolic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Neomycin
Neomycin {u} (Compound) resembles {v} (Compound) Paromomycin
Mycophenolic acid {u} (Compound) upregulates {v} (Gene) UBQLN2
UBQLN2 {u} (Gene) is upregulated by {v} (Compound) Paromomycin
Mycophenolic acid {u} (Compound) downregulates {v} (Gene) CDC20
CDC20 {u} (Gene) is downregulated by {v} (Compound) Paromomycin
Mycophenolic acid {u} (Compound) causes {v} (Side Effect) Diarrhoea
Diarrhoea {u} (Side Effect) is caused by {v} (Compound) Paromomycin
Mycophenolic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Kanamycin
Kanamycin {u} (Compound) resembles {v} (Compound) Tobramycin
Tobramycin {u} (Compound) resembles {v} (Compound) Paromomycin
Mycophenolic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Neomycin
Neomycin {u} (Compound) resembles {v} (Compound) Tobramycin
Tobramycin {u} (Compound) resembles {v} (Compound) Paromomycin
Mycophenolic acid {u} (Compound) upregulates {v} (Gene) UBQLN2
UBQLN2 {u} (Gene) regulates {v} (Gene) CDC20
CDC20 {u} (Gene) is downregulated by {v} (Compound) Paromomycin
Mycophenolic acid {u} (Compound) downregulates {v} (Gene) CDC20
CDC20 {u} (Gene) is regulated by {v} (Gene) UBQLN2
UBQLN2 {u} (Gene) is upregulated by {v} (Compound) Paromomycin
Mycophenolic acid {u} (Compound) causes {v} (Side Effect) Diarrhoea
Diarrhoea {u} (Side Effect) is caused by {v} (Compound) Tobramycin
Tobramycin {u} (Compound) resembles {v} (Compound) Paromomycin
Mycophenolic acid may cause a moderate interaction that could exacerbate diseases when taken with Kanamycin and Kanamycin (Compound) resembles Paromomycin (Compound)
Mycophenolic acid may cause a moderate interaction that could exacerbate diseases when taken with Neomycin and Neomycin (Compound) resembles Paromomycin (Compound)
Mycophenolic acid (Compound) upregulates UBQLN2 (Gene) and UBQLN2 (Gene) is upregulated by Paromomycin (Compound)
Mycophenolic acid (Compound) downregulates CDC20 (Gene) and CDC20 (Gene) is downregulated by Paromomycin (Compound)
Mycophenolic acid (Compound) causes Diarrhoea (Side Effect) and Diarrhoea (Side Effect) is caused by Paromomycin (Compound)
Mycophenolic acid may cause a moderate interaction that could exacerbate diseases when taken with Kanamycin and Kanamycin (Compound) resembles Tobramycin (Compound) and Tobramycin (Compound) resembles Paromomycin (Compound)
Mycophenolic acid may cause a moderate interaction that could exacerbate diseases when taken with Neomycin and Neomycin (Compound) resembles Tobramycin (Compound) and Tobramycin (Compound) resembles Paromomycin (Compound)
Mycophenolic acid (Compound) upregulates UBQLN2 (Gene) and UBQLN2 (Gene) regulates CDC20 (Gene) and CDC20 (Gene) is downregulated by Paromomycin (Compound)
Mycophenolic acid (Compound) downregulates CDC20 (Gene) and CDC20 (Gene) is regulated by UBQLN2 (Gene) and UBQLN2 (Gene) is upregulated by Paromomycin (Compound)
Mycophenolic acid (Compound) causes Diarrhoea (Side Effect) and Diarrhoea (Side Effect) is caused by Tobramycin (Compound) and Tobramycin (Compound) resembles Paromomycin (Compound)