DDInter1662 DDInter1016
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before beneficial effects are noticed. Sertraline displays enhanced safety or tolerability than other classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and other undesirable effects.[A1846,A187075,T28]
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose]. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. [sucrose]). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in patients with cirrhosis.[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.
Sertraline {u} (Compound) resembles {v} (Compound) Maprotiline
Sertraline {u} (Compound) binds {v} (Gene) CYP3A4
Sertraline {u} (Compound) upregulates {v} (Gene) CYP51A1
Sertraline {u} (Compound) palliates {v} (Disease) schizophrenia
Sertraline {u} (Compound) downregulates {v} (Gene) MRPL19
Sertraline {u} (Compound) causes {v} (Side Effect) Anaphylactic shock
Sertraline (Compound) resembles Maprotiline (Compound)
Sertraline (Compound) binds CYP3A4 (Gene)
Sertraline (Compound) upregulates CYP51A1 (Gene)
Sertraline (Compound) palliates schizophrenia (Disease)
Sertraline (Compound) downregulates MRPL19 (Gene)
Sertraline (Compound) causes Anaphylactic shock (Side Effect)