DDInter1782 DDInter396
Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone. ACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production of corticosteroids in the adrenal cortex. Tetracosactide exhibits the same activity as natural ACTH with regard to all its biological activities. The complex results in a product whose absorption in man is effected over a longer period of time as compared to corticotropin. Therefore, therapy may be maintained with less frequent administration.
Clevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.
Tetracosactide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nicardipine
Nicardipine {u} (Compound) resembles {v} (Compound) Clevidipine
Tetracosactide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nicardipine
Nicardipine {u} (Compound) resembles {v} (Compound) Nitrendipine
Nitrendipine {u} (Compound) resembles {v} (Compound) Clevidipine
Tetracosactide {u} may lead to a major life threatening interaction when taken with {v} Infliximab
Infliximab {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nicardipine
Nicardipine {u} (Compound) resembles {v} (Compound) Clevidipine
Tetracosactide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nicardipine
Nicardipine {u} (Compound) resembles {v} (Compound) Nifedipine
Nifedipine {u} (Compound) resembles {v} (Compound) Clevidipine
Tetracosactide {u} may lead to a major life threatening interaction when taken with {v} Fingolimod
Fingolimod {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nicardipine
Nicardipine {u} (Compound) resembles {v} (Compound) Clevidipine
Tetracosactide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Canagliflozin
Canagliflozin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nicardipine
Nicardipine {u} (Compound) resembles {v} (Compound) Clevidipine
Tetracosactide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Anakinra
Anakinra {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nicardipine
Nicardipine {u} (Compound) resembles {v} (Compound) Clevidipine
Tetracosactide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nicardipine
Nicardipine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Clevidipine
Tetracosactide {u} may lead to a major life threatening interaction when taken with {v} Fingolimod
Fingolimod {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Clevidipine
Tetracosactide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Canagliflozin
Canagliflozin {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Clevidipine
Tetracosactide may cause a moderate interaction that could exacerbate diseases when taken with Nicardipine and Nicardipine (Compound) resembles Clevidipine (Compound)
Tetracosactide may cause a moderate interaction that could exacerbate diseases when taken with Nicardipine and Nicardipine (Compound) resembles Nitrendipine (Compound) and Nitrendipine (Compound) resembles Clevidipine (Compound)
Tetracosactide may lead to a major life threatening interaction when taken with Infliximab and Infliximab may cause a moderate interaction that could exacerbate diseases when taken with Nicardipine and Nicardipine (Compound) resembles Clevidipine (Compound)
Tetracosactide may cause a moderate interaction that could exacerbate diseases when taken with Nicardipine and Nicardipine (Compound) resembles Nifedipine (Compound) and Nifedipine (Compound) resembles Clevidipine (Compound)
Tetracosactide may lead to a major life threatening interaction when taken with Fingolimod and Fingolimod may cause a moderate interaction that could exacerbate diseases when taken with Nicardipine and Nicardipine (Compound) resembles Clevidipine (Compound)
Tetracosactide may cause a moderate interaction that could exacerbate diseases when taken with Canagliflozin and Canagliflozin may cause a moderate interaction that could exacerbate diseases when taken with Nicardipine and Nicardipine (Compound) resembles Clevidipine (Compound)
Tetracosactide may cause a moderate interaction that could exacerbate diseases when taken with Anakinra and Anakinra may cause a moderate interaction that could exacerbate diseases when taken with Nicardipine and Nicardipine (Compound) resembles Clevidipine (Compound)
Tetracosactide may cause a moderate interaction that could exacerbate diseases when taken with Nicardipine and Nicardipine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Clevidipine (Compound)
Tetracosactide may lead to a major life threatening interaction when taken with Fingolimod and Fingolimod (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Clevidipine (Compound)
Tetracosactide may cause a moderate interaction that could exacerbate diseases when taken with Canagliflozin and Canagliflozin (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Clevidipine (Compound)