DDInter812 DDInter122
Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias.[A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not responded adequately to weight loss, diet, exercise, and other medications. Gemfibrozil was granted FDA approval on 21 December 1981.
Artesunate is indicated for the initial treatment of severe malaria. The World Health Organization recommends artesunate as first line treatment for severe malaria. Artesunate was developed out of a need for a more hydrophilic derivative of [artemisinin]. Artesunate was granted FDA approval on 26 May 2020.
Gemfibrozil {u} (Compound) resembles {v} (Compound) Bupranolol
Gemfibrozil {u} (Compound) treats {v} (Disease) coronary artery disease
Gemfibrozil {u} (Compound) binds {v} (Gene) CYP3A4
Gemfibrozil {u} (Compound) upregulates {v} (Gene) SRC
Gemfibrozil {u} (Compound) is included by {v} (Pharmacologic Class) PPAR alpha
Gemfibrozil {u} (Compound) downregulates {v} (Gene) GOLT1B
Gemfibrozil {u} (Compound) causes {v} (Side Effect) Urticaria
Gemfibrozil {u} may cause a minor interaction that can limit clinical effects when taken with {v} Brigatinib
Gemfibrozil {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acetohexamide
Gemfibrozil {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Enzalutamide
Gemfibrozil (Compound) resembles Bupranolol (Compound)
Gemfibrozil (Compound) treats coronary artery disease (Disease)
Gemfibrozil (Compound) binds CYP3A4 (Gene)
Gemfibrozil (Compound) upregulates SRC (Gene)
Gemfibrozil (Compound) is included by PPAR alpha (Pharmacologic Class)
Gemfibrozil (Compound) downregulates GOLT1B (Gene)
Gemfibrozil (Compound) causes Urticaria (Side Effect)
Gemfibrozil may cause a minor interaction that can limit clinical effects when taken with Brigatinib
Gemfibrozil may cause a moderate interaction that could exacerbate diseases when taken with Acetohexamide
Gemfibrozil may cause a moderate interaction that could exacerbate diseases when taken with Enzalutamide