DDInter68 DDInter957
A pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with diuretics to spare potassium loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705)
Iodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.
Amiloride {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Amiloride {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Diatrizoate
Diatrizoate {u} (Compound) resembles {v} (Compound) Iodipamide
Amiloride {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Irinotecan
Irinotecan {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Amiloride {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Irinotecan
Irinotecan {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Amiloride {u} may cause a minor interaction that can limit clinical effects when taken with {v} Tetracycline
Tetracycline {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Amiloride {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Diclofenac
Diclofenac {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Amiloride {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Diclofenac
Diclofenac {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Amiloride {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is associated with {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Amiloride {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iohexol
Iohexol {u} (Compound) is included by {v} (Pharmacologic Class) X-Ray Contrast Activity
X-Ray Contrast Activity {u} (Pharmacologic Class) includes {v} (Compound) Iodipamide
Amiloride {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iohexol
Iohexol {u} (Compound) downregulates {v} (Gene) NVL
NVL {u} (Gene) is downregulated by {v} (Compound) Iodipamide
Amiloride (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Iodipamide (Compound)
Amiloride (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Diatrizoate (Compound) and Diatrizoate (Compound) resembles Iodipamide (Compound)
Amiloride may cause a moderate interaction that could exacerbate diseases when taken with Irinotecan and Irinotecan (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Amiloride may cause a moderate interaction that could exacerbate diseases when taken with Irinotecan and Irinotecan (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Iodipamide (Compound)
Amiloride may cause a minor interaction that can limit clinical effects when taken with Tetracycline and Tetracycline (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Amiloride may cause a moderate interaction that could exacerbate diseases when taken with Diclofenac and Diclofenac (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Amiloride may cause a moderate interaction that could exacerbate diseases when taken with Diclofenac and Diclofenac (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Iodipamide (Compound)
Amiloride (Compound) treats hypertension (Disease) and hypertension (Disease) is associated with ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Amiloride may cause a moderate interaction that could exacerbate diseases when taken with Iohexol and Iohexol (Compound) is included by X-Ray Contrast Activity (Pharmacologic Class) and X-Ray Contrast Activity (Pharmacologic Class) includes Iodipamide (Compound)
Amiloride may cause a moderate interaction that could exacerbate diseases when taken with Iohexol and Iohexol (Compound) downregulates NVL (Gene) and NVL (Gene) is downregulated by Iodipamide (Compound)