DDInter815 DDInter1473
Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea_ in 1963. It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability.[A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment of severe gram-negative infections including those caused by _Pseudomonas aeruginosa_.[A233325,A234359,A234364] There is the added benefit of synergy when gentamicin is co-administered with other antibacterials such as beta-lactams. This synergistic activity is not only important for the treatment of complex infections, but can also contribute to dose optimization and reduced adverse effects.[A234359,A234364] Although gentamicin is well-established and may be used in a variety of clinical applications,
Pipecuronium is a piperazinyl androstane derivative which is a non-depolarizing neuromuscular blocking agent.
Gentamicin {u} may lead to a major life threatening interaction when taken with {v} Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Gentamicin {u} may lead to a major life threatening interaction when taken with {v} Rocuronium
Rocuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Gentamicin {u} may lead to a major life threatening interaction when taken with {v} Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Rocuronium
Rocuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Gentamicin {u} may lead to a major life threatening interaction when taken with {v} Rocuronium
Rocuronium {u} (Compound) resembles {v} (Compound) Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Gentamicin {u} (Compound) causes {v} (Side Effect) Anaphylactoid reaction
Anaphylactoid reaction {u} (Side Effect) is caused by {v} (Compound) Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Gentamicin {u} may lead to a major life threatening interaction when taken with {v} Vecuronium
Vecuronium {u} (Compound) resembles {v} (Compound) Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Gentamicin {u} may lead to a major life threatening interaction when taken with {v} Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Vecuronium
Vecuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Gentamicin {u} (Compound) causes {v} (Side Effect) Anaphylactoid reaction
Anaphylactoid reaction {u} (Side Effect) is caused by {v} (Compound) Rocuronium
Rocuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Gentamicin {u} may lead to a major life threatening interaction when taken with {v} Pancuronium
Pancuronium {u} (Compound) binds {v} (Gene) CHRNB1
CHRNB1 {u} (Gene) is bound by {v} (Compound) Pipecuronium
Gentamicin {u} may lead to a major life threatening interaction when taken with {v} Rocuronium
Rocuronium {u} (Compound) binds {v} (Gene) CHRNB1
CHRNB1 {u} (Gene) is bound by {v} (Compound) Pipecuronium
Gentamicin may lead to a major life threatening interaction when taken with Pancuronium and Pancuronium (Compound) resembles Pipecuronium (Compound)
Gentamicin may lead to a major life threatening interaction when taken with Rocuronium and Rocuronium (Compound) resembles Pipecuronium (Compound)
Gentamicin may lead to a major life threatening interaction when taken with Pancuronium and Pancuronium (Compound) resembles Rocuronium (Compound) and Rocuronium (Compound) resembles Pipecuronium (Compound)
Gentamicin may lead to a major life threatening interaction when taken with Rocuronium and Rocuronium (Compound) resembles Pancuronium (Compound) and Pancuronium (Compound) resembles Pipecuronium (Compound)
Gentamicin (Compound) causes Anaphylactoid reaction (Side Effect) and Anaphylactoid reaction (Side Effect) is caused by Pancuronium (Compound) and Pancuronium (Compound) resembles Pipecuronium (Compound)
Gentamicin may lead to a major life threatening interaction when taken with Vecuronium and Vecuronium (Compound) resembles Pancuronium (Compound) and Pancuronium (Compound) resembles Pipecuronium (Compound)
Gentamicin may lead to a major life threatening interaction when taken with Pancuronium and Pancuronium (Compound) resembles Vecuronium (Compound) and Vecuronium (Compound) resembles Pipecuronium (Compound)
Gentamicin (Compound) causes Anaphylactoid reaction (Side Effect) and Anaphylactoid reaction (Side Effect) is caused by Rocuronium (Compound) and Rocuronium (Compound) resembles Pipecuronium (Compound)
Gentamicin may lead to a major life threatening interaction when taken with Pancuronium and Pancuronium (Compound) binds CHRNB1 (Gene) and CHRNB1 (Gene) is bound by Pipecuronium (Compound)
Gentamicin may lead to a major life threatening interaction when taken with Rocuronium and Rocuronium (Compound) binds CHRNB1 (Gene) and CHRNB1 (Gene) is bound by Pipecuronium (Compound)