DDInter1791 DDInter534
A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly for asthma, bronchospasm, and COPD.
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome. (From Martindale, The Extra Pharmacopoeia, 30th ed, p589) Given diazepam's storied history as a commonly used and effective medication for a variety of indications, contemporary advancements in the formulation and administration of the agent include the development and US FDA approval of an auto-injectable formulation for the rapid treatment of uncontrolled seizures in 2015-2016 . Combining diazepam, a proven effective therapy for acute repetitive seizures, with an auto-injector designed for subcutaneous administration that is quickly and easily administered offers the potential for complete, consistent drug absorption and rapid onset of effect . This current development is subsequently an important addition to the rescue therapy tool chest for patients with epilepsy .
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Quazepam
Quazepam {u} (Compound) resembles {v} (Compound) Diazepam
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Oxazepam
Oxazepam {u} (Compound) resembles {v} (Compound) Diazepam
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Lorazepam
Lorazepam {u} (Compound) resembles {v} (Compound) Diazepam
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Temazepam
Temazepam {u} (Compound) resembles {v} (Compound) Diazepam
Theophylline {u} (Compound) binds {v} (Gene) CYP2C9
CYP2C9 {u} (Gene) is bound by {v} (Compound) Diazepam
Theophylline {u} (Compound) causes {v} (Side Effect) Phlebitis
Phlebitis {u} (Side Effect) is caused by {v} (Compound) Diazepam
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Quazepam
Quazepam {u} (Compound) resembles {v} (Compound) Flunitrazepam
Flunitrazepam {u} (Compound) resembles {v} (Compound) Diazepam
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Oxazepam
Oxazepam {u} (Compound) resembles {v} (Compound) Bromazepam
Bromazepam {u} (Compound) resembles {v} (Compound) Diazepam
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Lorazepam
Lorazepam {u} (Compound) resembles {v} (Compound) Quazepam
Quazepam {u} (Compound) resembles {v} (Compound) Diazepam
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Chlordiazepoxide
Chlordiazepoxide {u} (Compound) resembles {v} (Compound) Oxazepam
Oxazepam {u} (Compound) resembles {v} (Compound) Diazepam
Theophylline may cause a minor interaction that can limit clinical effects when taken with Quazepam and Quazepam (Compound) resembles Diazepam (Compound)
Theophylline may cause a minor interaction that can limit clinical effects when taken with Oxazepam and Oxazepam (Compound) resembles Diazepam (Compound)
Theophylline may cause a minor interaction that can limit clinical effects when taken with Lorazepam and Lorazepam (Compound) resembles Diazepam (Compound)
Theophylline may cause a minor interaction that can limit clinical effects when taken with Temazepam and Temazepam (Compound) resembles Diazepam (Compound)
Theophylline (Compound) binds CYP2C9 (Gene) and CYP2C9 (Gene) is bound by Diazepam (Compound)
Theophylline (Compound) causes Phlebitis (Side Effect) and Phlebitis (Side Effect) is caused by Diazepam (Compound)
Theophylline may cause a minor interaction that can limit clinical effects when taken with Quazepam and Quazepam (Compound) resembles Flunitrazepam (Compound) and Flunitrazepam (Compound) resembles Diazepam (Compound)
Theophylline may cause a minor interaction that can limit clinical effects when taken with Oxazepam and Oxazepam (Compound) resembles Bromazepam (Compound) and Bromazepam (Compound) resembles Diazepam (Compound)
Theophylline may cause a minor interaction that can limit clinical effects when taken with Lorazepam and Lorazepam (Compound) resembles Quazepam (Compound) and Quazepam (Compound) resembles Diazepam (Compound)
Theophylline may cause a minor interaction that can limit clinical effects when taken with Chlordiazepoxide and Chlordiazepoxide (Compound) resembles Oxazepam (Compound) and Oxazepam (Compound) resembles Diazepam (Compound)