DDInter596 DDInter1756
Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed molecular mechanisms have yet to be understood, doxorubicin is generally thought to exert its effect through DNA intercalation, which eventually leads to DNA damage and the generation of reactive oxygen species. Thanks to its efficacy and broad effect, doxorubicin was approved by the FDA in 1974 to treat a variety of cancer, including but not limited to breast, lung, gastric, ovarian, thyroid, non-Hodgkin’s and Hodgkin’s lymphoma, multiple myel
Telavancin is a semi-synthetic derivative of vanocymycin that has bactericidal activity against Methicillin-resistant Staphylococcus aureus (MRSA) and other gram-positive bacteria. MRSA is an important pathogen capable of causing hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP), and skin and subcutaneous tissue infections among others.
Doxorubicin {u} (Compound) causes {v} (Side Effect) Phlebitis
Phlebitis {u} (Side Effect) is caused by {v} (Compound) Telavancin
Doxorubicin {u} (Compound) resembles {v} (Compound) Idarubicin
Idarubicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Telavancin
Doxorubicin {u} (Compound) causes {v} (Side Effect) Phlebitis
Phlebitis {u} (Side Effect) is caused by {v} (Compound) Vancomycin
Vancomycin {u} (Compound) resembles {v} (Compound) Telavancin
Doxorubicin {u} (Compound) causes {v} (Side Effect) Rash
Rash {u} (Side Effect) is caused by {v} (Compound) Oritavancin
Oritavancin {u} (Compound) resembles {v} (Compound) Telavancin
Doxorubicin {u} (Compound) causes {v} (Side Effect) Hyperkalaemia
Hyperkalaemia {u} (Side Effect) is caused by {v} (Compound) Doxepin
Doxepin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Telavancin
Doxorubicin {u} (Compound) resembles {v} (Compound) Idarubicin
Idarubicin {u} (Compound) causes {v} (Side Effect) Phlebitis
Phlebitis {u} (Side Effect) is caused by {v} (Compound) Telavancin
Doxorubicin {u} (Compound) causes {v} (Side Effect) Diarrhoea
Diarrhoea {u} (Side Effect) is caused by {v} (Compound) Metronidazole
Metronidazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Telavancin
Doxorubicin {u} (Compound) causes {v} (Side Effect) Abscess
Abscess {u} (Side Effect) is caused by {v} (Compound) Degarelix
Degarelix {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Telavancin
Doxorubicin {u} (Compound) causes {v} (Side Effect) Phlebitis
Phlebitis {u} (Side Effect) is caused by {v} (Compound) Dolasetron
Dolasetron {u} may lead to a major life threatening interaction when taken with {v} Telavancin
Doxorubicin {u} (Compound) causes {v} (Side Effect) Abscess
Abscess {u} (Side Effect) is caused by {v} (Compound) Crizotinib
Crizotinib {u} may lead to a major life threatening interaction when taken with {v} Telavancin
Doxorubicin (Compound) causes Phlebitis (Side Effect) and Phlebitis (Side Effect) is caused by Telavancin (Compound)
Doxorubicin (Compound) resembles Idarubicin (Compound) and Idarubicin may cause a moderate interaction that could exacerbate diseases when taken with Telavancin
Doxorubicin (Compound) causes Phlebitis (Side Effect) and Phlebitis (Side Effect) is caused by Vancomycin (Compound) and Vancomycin (Compound) resembles Telavancin (Compound)
Doxorubicin (Compound) causes Rash (Side Effect) and Rash (Side Effect) is caused by Oritavancin (Compound) and Oritavancin (Compound) resembles Telavancin (Compound)
Doxorubicin (Compound) causes Hyperkalaemia (Side Effect) and Hyperkalaemia (Side Effect) is caused by Doxepin (Compound) and Doxepin may cause a moderate interaction that could exacerbate diseases when taken with Telavancin
Doxorubicin (Compound) resembles Idarubicin (Compound) and Idarubicin (Compound) causes Phlebitis (Side Effect) and Phlebitis (Side Effect) is caused by Telavancin (Compound)
Doxorubicin (Compound) causes Diarrhoea (Side Effect) and Diarrhoea (Side Effect) is caused by Metronidazole (Compound) and Metronidazole may cause a minor interaction that can limit clinical effects when taken with Telavancin
Doxorubicin (Compound) causes Abscess (Side Effect) and Abscess (Side Effect) is caused by Degarelix (Compound) and Degarelix may cause a moderate interaction that could exacerbate diseases when taken with Telavancin
Doxorubicin (Compound) causes Phlebitis (Side Effect) and Phlebitis (Side Effect) is caused by Dolasetron (Compound) and Dolasetron may lead to a major life threatening interaction when taken with Telavancin
Doxorubicin (Compound) causes Abscess (Side Effect) and Abscess (Side Effect) is caused by Crizotinib (Compound) and Crizotinib may lead to a major life threatening interaction when taken with Telavancin