DDInter258 DDInter1647
A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Scopolamine is a tropane alkaloid isolated from members of the _Solanaceae_ family of plants, similar to [atropine] and [hyoscyamine], all of which structurally mimic the natural neurotransmitter [acetylcholine].[A228423, A228763] Scopolamine was first synthesized in 1959, but to date, synthesis remains less efficient than extracting scopolamine from plants. As an acetylcholine analogue, scopolamine can antagonize muscarinic acetylcholine receptors (mAChRs) in the central nervous system and throughout the body, inducing several therapeutic and adverse effects related to alteration of parasympathetic nervous system and cholinergic signalling.[A228758, L31578] Due to its dose-dependent adverse effects, scopolamine was the first drug to be offered commercially as a transdermal delivery system, Scopoderm TTS®, in 1981.[A228423, A228758] As a result of its anticholinergic effects, scopolamine is being investigated for diverse therapeutic applications; currently, it is approved for the prevention of nausea and vomiting associated with motion sickness and surgical procedures.[A228773, L31578] Scopolamine was first approved by the FDA on December 31, 1979, and is currently available as both oral tablets and a transdermal delivery system.
Butorphanol {u} (Compound) causes {v} (Side Effect) Photophobia
Photophobia {u} (Side Effect) is caused by {v} (Compound) Scopolamine
Butorphanol {u} (Compound) resembles {v} (Compound) Nalbuphine
Nalbuphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Scopolamine
Butorphanol {u} (Compound) resembles {v} (Compound) Pentazocine
Pentazocine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Scopolamine
Butorphanol {u} (Compound) causes {v} (Side Effect) Photophobia
Photophobia {u} (Side Effect) is caused by {v} (Compound) Hyoscyamine
Hyoscyamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Scopolamine
Butorphanol {u} (Compound) causes {v} (Side Effect) Drug withdrawal syndrome
Drug withdrawal syndrome {u} (Side Effect) is caused by {v} (Compound) Paliperidone
Paliperidone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Scopolamine
Butorphanol {u} (Compound) resembles {v} (Compound) Nalbuphine
Nalbuphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Hyoscyamine
Hyoscyamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Scopolamine
Butorphanol {u} (Compound) resembles {v} (Compound) Levallorphan
Levallorphan {u} (Compound) resembles {v} (Compound) Pentazocine
Pentazocine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Scopolamine
Butorphanol {u} (Compound) resembles {v} (Compound) Pentazocine
Pentazocine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Hyoscyamine
Hyoscyamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Scopolamine
Butorphanol {u} (Compound) causes {v} (Side Effect) Photophobia
Photophobia {u} (Side Effect) is caused by {v} (Compound) Indapamide
Indapamide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Scopolamine
Butorphanol {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Methylscopolamine bromide
Methylscopolamine bromide {u} (Compound) resembles {v} (Compound) Scopolamine
Butorphanol (Compound) causes Photophobia (Side Effect) and Photophobia (Side Effect) is caused by Scopolamine (Compound)
Butorphanol (Compound) resembles Nalbuphine (Compound) and Nalbuphine may cause a moderate interaction that could exacerbate diseases when taken with Scopolamine
Butorphanol (Compound) resembles Pentazocine (Compound) and Pentazocine may cause a moderate interaction that could exacerbate diseases when taken with Scopolamine
Butorphanol (Compound) causes Photophobia (Side Effect) and Photophobia (Side Effect) is caused by Hyoscyamine (Compound) and Hyoscyamine may cause a moderate interaction that could exacerbate diseases when taken with Scopolamine
Butorphanol (Compound) causes Drug withdrawal syndrome (Side Effect) and Drug withdrawal syndrome (Side Effect) is caused by Paliperidone (Compound) and Paliperidone may cause a moderate interaction that could exacerbate diseases when taken with Scopolamine
Butorphanol (Compound) resembles Nalbuphine (Compound) and Nalbuphine may cause a moderate interaction that could exacerbate diseases when taken with Hyoscyamine and Hyoscyamine may cause a moderate interaction that could exacerbate diseases when taken with Scopolamine
Butorphanol (Compound) resembles Levallorphan (Compound) and Levallorphan (Compound) resembles Pentazocine (Compound) and Pentazocine may cause a moderate interaction that could exacerbate diseases when taken with Scopolamine
Butorphanol (Compound) resembles Pentazocine (Compound) and Pentazocine may cause a moderate interaction that could exacerbate diseases when taken with Hyoscyamine and Hyoscyamine may cause a moderate interaction that could exacerbate diseases when taken with Scopolamine
Butorphanol (Compound) causes Photophobia (Side Effect) and Photophobia (Side Effect) is caused by Indapamide (Compound) and Indapamide may cause a minor interaction that can limit clinical effects when taken with Scopolamine
Butorphanol (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Methylscopolamine bromide (Compound) and Methylscopolamine bromide (Compound) resembles Scopolamine (Compound)