DDInter1570 DDInter246
Chronic angina is a common cardiovascular condition affecting millions worldwide and causes significant disability while interfering with daily activities. Ranolazine is a well-tolerated piperazine derivative used for the management of this condition, offering relief from uncomfortable and debilitating symptoms. With a mechanism of action different from drugs used to treat the same condition, ranolazine is a promising anti-anginal therapy. It was originally approved by the FDA in 2006.
Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994. It is also available in a combination product with [formoterol].
Ranolazine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Budesonide
Ranolazine {u} (Compound) causes {v} (Side Effect) Confusional state
Confusional state {u} (Side Effect) is caused by {v} (Compound) Budesonide
Ranolazine {u} (Compound) resembles {v} (Compound) Carvedilol
Carvedilol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Budesonide
Ranolazine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Paramethasone
Paramethasone {u} (Compound) resembles {v} (Compound) Budesonide
Ranolazine {u} (Compound) causes {v} (Side Effect) Confusional state
Confusional state {u} (Side Effect) is caused by {v} (Compound) Methylprednisolone
Methylprednisolone {u} (Compound) resembles {v} (Compound) Budesonide
Ranolazine {u} (Compound) causes {v} (Side Effect) Somnolence
Somnolence {u} (Side Effect) is caused by {v} (Compound) Orciprenaline
Orciprenaline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Budesonide
Ranolazine {u} (Compound) resembles {v} (Compound) Guaifenesin
Guaifenesin {u} (Compound) resembles {v} (Compound) Penbutolol
Penbutolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Budesonide
Ranolazine {u} (Compound) resembles {v} (Compound) Carvedilol
Carvedilol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Betamethasone
Betamethasone {u} (Compound) resembles {v} (Compound) Budesonide
Ranolazine {u} (Compound) causes {v} (Side Effect) Confusional state
Confusional state {u} (Side Effect) is caused by {v} (Compound) Ticagrelor
Ticagrelor {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Budesonide
Ranolazine {u} (Compound) causes {v} (Side Effect) Dysuria
Dysuria {u} (Side Effect) is caused by {v} (Compound) Reserpine
Reserpine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Budesonide
Ranolazine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Budesonide (Compound)
Ranolazine (Compound) causes Confusional state (Side Effect) and Confusional state (Side Effect) is caused by Budesonide (Compound)
Ranolazine (Compound) resembles Carvedilol (Compound) and Carvedilol may cause a moderate interaction that could exacerbate diseases when taken with Budesonide
Ranolazine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Paramethasone (Compound) and Paramethasone (Compound) resembles Budesonide (Compound)
Ranolazine (Compound) causes Confusional state (Side Effect) and Confusional state (Side Effect) is caused by Methylprednisolone (Compound) and Methylprednisolone (Compound) resembles Budesonide (Compound)
Ranolazine (Compound) causes Somnolence (Side Effect) and Somnolence (Side Effect) is caused by Orciprenaline (Compound) and Orciprenaline may cause a minor interaction that can limit clinical effects when taken with Budesonide
Ranolazine (Compound) resembles Guaifenesin (Compound) and Guaifenesin (Compound) resembles Penbutolol (Compound) and Penbutolol may cause a moderate interaction that could exacerbate diseases when taken with Budesonide
Ranolazine (Compound) resembles Carvedilol (Compound) and Carvedilol may cause a moderate interaction that could exacerbate diseases when taken with Betamethasone and Betamethasone (Compound) resembles Budesonide (Compound)
Ranolazine (Compound) causes Confusional state (Side Effect) and Confusional state (Side Effect) is caused by Ticagrelor (Compound) and Ticagrelor may cause a moderate interaction that could exacerbate diseases when taken with Budesonide
Ranolazine (Compound) causes Dysuria (Side Effect) and Dysuria (Side Effect) is caused by Reserpine (Compound) and Reserpine may cause a moderate interaction that could exacerbate diseases when taken with Budesonide