DDInter1513 DDInter1676
Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Siponimod, also known as _Mayzent_, by Novartis, is a new drug formulated for the management of Multiple Sclerosis (MS). It was approved by the FDA on March 26, 2019 and by Health Canada on February 20, 2020. This drug is considered a _sphingosine-1-phosphate (S1P) receptor modulator_ and is thought to play a role in suppressing the central nervous system inflammation that is associated with MS [FDA label]. Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system that is chronic and inflammatory, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of life. Symptoms may include but are not limited to fatigue, gait changes, bowel or bladder dysfunction, abnormal muscle twitching, vision disturbance, and depressing or mood swings. MS is one of the most common causes of neurological disability in young adults and is found to occur more frequently in women than in men.[A176474,L5792]
Prednisolone {u} (Compound) resembles {v} (Compound) Fluprednidene Acetate
Prednisolone {u} (Compound) resembles {v} (Compound) Hydrocortamate
Prednisolone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Testosterone
Prednisolone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fluoxymesterone
Prednisolone {u} (Compound) treats {v} (Disease) chronic obstructive pulmonary disease
Prednisolone {u} (Compound) binds {v} (Gene) NR3C1
Prednisolone {u} (Compound) upregulates {v} (Gene) NFKBIA
Prednisolone {u} (Compound) palliates {v} (Disease) idiopathic pulmonary fibrosis
Prednisolone {u} (Compound) is included by {v} (Pharmacologic Class) Corticosteroid Hormone Receptor Agonists
Prednisolone {u} (Compound) downregulates {v} (Gene) FHL2
Prednisolone (Compound) resembles Fluprednidene Acetate (Compound)
Prednisolone (Compound) resembles Hydrocortamate (Compound)
Prednisolone may cause a moderate interaction that could exacerbate diseases when taken with Testosterone
Prednisolone may cause a moderate interaction that could exacerbate diseases when taken with Fluoxymesterone
Prednisolone (Compound) treats chronic obstructive pulmonary disease (Disease)
Prednisolone (Compound) binds NR3C1 (Gene)
Prednisolone (Compound) upregulates NFKBIA (Gene)
Prednisolone (Compound) palliates idiopathic pulmonary fibrosis (Disease)
Prednisolone (Compound) is included by Corticosteroid Hormone Receptor Agonists (Pharmacologic Class)
Prednisolone (Compound) downregulates FHL2 (Gene)