DDInter1815 DDInter1180
Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma.[A180163,L7084,L7087,L7090,L7093] Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation.[A180163,L7084,L7087,L7090,L7093] Tiotropium is more specific for the subset of muscarinic receptors commonly found in the lungs than [ipratropium]. Tiotropium was granted FDA approval on 30 January 2004.
Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Tiotropium {u} (Compound) resembles {v} (Compound) Methylscopolamine bromide
Tiotropium {u} (Compound) treats {v} (Disease) asthma
Tiotropium {u} (Compound) binds {v} (Gene) CHRM2
Tiotropium {u} (Compound) causes {v} (Side Effect) Oropharyngeal candidiasis
Tiotropium {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cimetidine
Tiotropium {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Propiomazine
Tiotropium {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenindamine
Tiotropium {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Aclidinium
Tiotropium (Compound) resembles Methylscopolamine bromide (Compound)
Tiotropium (Compound) treats asthma (Disease)
Tiotropium (Compound) binds CHRM2 (Gene)
Tiotropium (Compound) causes Oropharyngeal candidiasis (Side Effect)
Tiotropium may cause a minor interaction that can limit clinical effects when taken with Cimetidine
Tiotropium may cause a moderate interaction that could exacerbate diseases when taken with Propiomazine
Tiotropium may cause a moderate interaction that could exacerbate diseases when taken with Phenindamine
Tiotropium (Compound) resembles Aclidinium (Compound) and Tiotropium may cause a moderate interaction that could exacerbate diseases when taken with Aclidinium