DDInter258 DDInter1448
A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Phentolamine is a reversible, non-selective alpha-adrenergic blocker that induces vasodilation. While initially introduced to the market for the treatment of hypertension, this clinical use was halted due to cardiovascular and gastrointestinal adverse effects with the prolonged use of large oral doses of phentolamine.[A261781, A261786] It has several therapeutic uses, including the treatment of hypertensive episodes, prevention of norepinephrine-induced extravasation, diagnosis of pheochromocytoma, reversal of soft-tissue anesthesia, and treatment of pharmacologically-induced mydriasis.[L48420, L48415, L48390] Phentolamine is administered intravenously, intramuscularly, submucosally, and topically.
Butorphanol {u} (Compound) causes {v} (Side Effect) Tachycardia
Tachycardia {u} (Side Effect) is caused by {v} (Compound) Phentolamine
Butorphanol {u} (Compound) resembles {v} (Compound) Nalbuphine
Nalbuphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phentolamine
Butorphanol {u} (Compound) resembles {v} (Compound) Pentazocine
Pentazocine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phentolamine
Butorphanol {u} (Compound) causes {v} (Side Effect) Tachycardia
Tachycardia {u} (Side Effect) is caused by {v} (Compound) Dronabinol
Dronabinol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phentolamine
Butorphanol {u} (Compound) causes {v} (Side Effect) Vomiting
Vomiting {u} (Side Effect) is caused by {v} (Compound) Fenoldopam
Fenoldopam {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phentolamine
Butorphanol {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Naphazoline
Naphazoline {u} (Compound) resembles {v} (Compound) Phentolamine
Butorphanol {u} (Compound) resembles {v} (Compound) Nalbuphine
Nalbuphine {u} (Compound) causes {v} (Side Effect) Tachycardia
Tachycardia {u} (Side Effect) is caused by {v} (Compound) Phentolamine
Butorphanol {u} (Compound) resembles {v} (Compound) Levallorphan
Levallorphan {u} (Compound) resembles {v} (Compound) Pentazocine
Pentazocine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phentolamine
Butorphanol {u} (Compound) resembles {v} (Compound) Pentazocine
Pentazocine {u} (Compound) binds {v} (Gene) SIGMAR1
SIGMAR1 {u} (Gene) is bound by {v} (Compound) Phentolamine
Butorphanol {u} (Compound) resembles {v} (Compound) Naltrexone
Naltrexone {u} may lead to a major life threatening interaction when taken with {v} Oxycodone
Oxycodone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phentolamine
Butorphanol (Compound) causes Tachycardia (Side Effect) and Tachycardia (Side Effect) is caused by Phentolamine (Compound)
Butorphanol (Compound) resembles Nalbuphine (Compound) and Nalbuphine may cause a moderate interaction that could exacerbate diseases when taken with Phentolamine
Butorphanol (Compound) resembles Pentazocine (Compound) and Pentazocine may cause a moderate interaction that could exacerbate diseases when taken with Phentolamine
Butorphanol (Compound) causes Tachycardia (Side Effect) and Tachycardia (Side Effect) is caused by Dronabinol (Compound) and Dronabinol may cause a moderate interaction that could exacerbate diseases when taken with Phentolamine
Butorphanol (Compound) causes Vomiting (Side Effect) and Vomiting (Side Effect) is caused by Fenoldopam (Compound) and Fenoldopam may cause a moderate interaction that could exacerbate diseases when taken with Phentolamine
Butorphanol (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Naphazoline (Compound) and Naphazoline (Compound) resembles Phentolamine (Compound)
Butorphanol (Compound) resembles Nalbuphine (Compound) and Nalbuphine (Compound) causes Tachycardia (Side Effect) and Tachycardia (Side Effect) is caused by Phentolamine (Compound)
Butorphanol (Compound) resembles Levallorphan (Compound) and Levallorphan (Compound) resembles Pentazocine (Compound) and Pentazocine may cause a moderate interaction that could exacerbate diseases when taken with Phentolamine
Butorphanol (Compound) resembles Pentazocine (Compound) and Pentazocine (Compound) binds SIGMAR1 (Gene) and SIGMAR1 (Gene) is bound by Phentolamine (Compound)
Butorphanol (Compound) resembles Naltrexone (Compound) and Naltrexone may lead to a major life threatening interaction when taken with Oxycodone and Oxycodone may cause a moderate interaction that could exacerbate diseases when taken with Phentolamine