DDInter458 DDInter25
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus _Beauveria nivea_. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
Acyclovir is a nucleotide analog antiviral used to treat herpes simplex, _Varicella zoster_, herpes zoster, herpes labialis, and acute herpetic keratitis[L7303,L7315,L7318,L7321,L7324,L7327]. Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old. Acyclovir was granted FDA approval on 29 March 1982.
Cyclosporine {u} (Compound) binds {v} (Gene) SLC22A6
SLC22A6 {u} (Gene) is bound by {v} (Compound) Acyclovir
Cyclosporine {u} (Compound) upregulates {v} (Gene) HYOU1
HYOU1 {u} (Gene) is upregulated by {v} (Compound) Acyclovir
Cyclosporine {u} (Compound) downregulates {v} (Gene) PUF60
PUF60 {u} (Gene) is downregulated by {v} (Compound) Acyclovir
Cyclosporine {u} (Compound) upregulates {v} (Gene) AARS
AARS {u} (Gene) is downregulated by {v} (Compound) Acyclovir
Cyclosporine {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Acyclovir
Cyclosporine {u} (Compound) binds {v} (Gene) SLC22A6
SLC22A6 {u} (Gene) is bound by {v} (Compound) Ganciclovir
Ganciclovir {u} (Compound) resembles {v} (Compound) Acyclovir
Cyclosporine {u} (Compound) binds {v} (Gene) SLC10A2
SLC10A2 {u} (Gene) is bound by {v} (Compound) Valaciclovir
Valaciclovir {u} (Compound) resembles {v} (Compound) Acyclovir
Cyclosporine {u} (Compound) upregulates {v} (Gene) HYOU1
HYOU1 {u} (Gene) regulates {v} (Gene) EGF
EGF {u} (Gene) is upregulated by {v} (Compound) Acyclovir
Cyclosporine {u} (Compound) downregulates {v} (Gene) PUF60
PUF60 {u} (Gene) regulates {v} (Gene) TBXA2R
TBXA2R {u} (Gene) is upregulated by {v} (Compound) Acyclovir
Cyclosporine {u} (Compound) downregulates {v} (Gene) SDHB
SDHB {u} (Gene) is regulated by {v} (Gene) ORC1
ORC1 {u} (Gene) is upregulated by {v} (Compound) Acyclovir
Cyclosporine (Compound) binds SLC22A6 (Gene) and SLC22A6 (Gene) is bound by Acyclovir (Compound)
Cyclosporine (Compound) upregulates HYOU1 (Gene) and HYOU1 (Gene) is upregulated by Acyclovir (Compound)
Cyclosporine (Compound) downregulates PUF60 (Gene) and PUF60 (Gene) is downregulated by Acyclovir (Compound)
Cyclosporine (Compound) upregulates AARS (Gene) and AARS (Gene) is downregulated by Acyclovir (Compound)
Cyclosporine (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Acyclovir (Compound)
Cyclosporine (Compound) binds SLC22A6 (Gene) and SLC22A6 (Gene) is bound by Ganciclovir (Compound) and Ganciclovir (Compound) resembles Acyclovir (Compound)
Cyclosporine (Compound) binds SLC10A2 (Gene) and SLC10A2 (Gene) is bound by Valaciclovir (Compound) and Valaciclovir (Compound) resembles Acyclovir (Compound)
Cyclosporine (Compound) upregulates HYOU1 (Gene) and HYOU1 (Gene) regulates EGF (Gene) and EGF (Gene) is upregulated by Acyclovir (Compound)
Cyclosporine (Compound) downregulates PUF60 (Gene) and PUF60 (Gene) regulates TBXA2R (Gene) and TBXA2R (Gene) is upregulated by Acyclovir (Compound)
Cyclosporine (Compound) downregulates SDHB (Gene) and SDHB (Gene) is regulated by ORC1 (Gene) and ORC1 (Gene) is upregulated by Acyclovir (Compound)