DDInter675 DDInter20
Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate of heart contractions. Esmolol prevents the action of two naturally occurring substances: epinephrine and norepinephrine. The FDA withdrew its approval for the use of all parenteral dosage form drug products containing esmolol hydrochloride that supply 250 milligrams/milliliter of concentrated esmolol per 10-milliliter ampule. Other esmolol formulations are still available for use.
Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) [FDA label]. Interestingly, the results of various studies have demonstrated that long-term use of acetylsalicylic acid may decrease the risk of various cancers, including colorectal, esophageal, breast, lung, prostate, liver and skin cancer . Aspirin is classified as a _non-selective cyclooxygenase (COX) inhibitor_ [A32682, A177268] and is available in many doses and forms, including chewable tablets, suppositories, extended release formulations, and others . Acetylsalicylic acid is a very common cause of accidental poisoning in young children. It should be kept out of reach from young children, toddlers, and infants [FDA label].
Esmolol {u} (Compound) causes {v} (Side Effect) Convulsion
Convulsion {u} (Side Effect) is caused by {v} (Compound) Acetylsalicylic acid
Esmolol {u} (Compound) resembles {v} (Compound) Metoprolol
Metoprolol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Acetylsalicylic acid
Esmolol {u} (Compound) resembles {v} (Compound) Acebutolol
Acebutolol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Acetylsalicylic acid
Esmolol {u} (Compound) resembles {v} (Compound) Pindolol
Pindolol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Acetylsalicylic acid
Esmolol {u} (Compound) resembles {v} (Compound) Ibuprofen
Ibuprofen {u} may lead to a major life threatening interaction when taken with {v} Acetylsalicylic acid
Esmolol {u} (Compound) causes {v} (Side Effect) Convulsion
Convulsion {u} (Side Effect) is caused by {v} (Compound) Mefenamic acid
Mefenamic acid {u} (Compound) resembles {v} (Compound) Acetylsalicylic acid
Esmolol {u} (Compound) causes {v} (Side Effect) Agitation
Agitation {u} (Side Effect) is caused by {v} (Compound) Pantoprazole
Pantoprazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Acetylsalicylic acid
Esmolol {u} (Compound) resembles {v} (Compound) Metoprolol
Metoprolol {u} (Compound) binds {v} (Gene) CYP2C19
CYP2C19 {u} (Gene) is bound by {v} (Compound) Acetylsalicylic acid
Esmolol {u} (Compound) resembles {v} (Compound) Bisoprolol
Bisoprolol {u} (Compound) causes {v} (Side Effect) Polyuria
Polyuria {u} (Side Effect) is caused by {v} (Compound) Acetylsalicylic acid
Esmolol {u} (Compound) resembles {v} (Compound) Acebutolol
Acebutolol {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Acetylsalicylic acid
Esmolol (Compound) causes Convulsion (Side Effect) and Convulsion (Side Effect) is caused by Acetylsalicylic acid (Compound)
Esmolol (Compound) resembles Metoprolol (Compound) and Metoprolol may cause a minor interaction that can limit clinical effects when taken with Acetylsalicylic acid
Esmolol (Compound) resembles Acebutolol (Compound) and Acebutolol may cause a minor interaction that can limit clinical effects when taken with Acetylsalicylic acid
Esmolol (Compound) resembles Pindolol (Compound) and Pindolol may cause a minor interaction that can limit clinical effects when taken with Acetylsalicylic acid
Esmolol (Compound) resembles Ibuprofen (Compound) and Ibuprofen may lead to a major life threatening interaction when taken with Acetylsalicylic acid
Esmolol (Compound) causes Convulsion (Side Effect) and Convulsion (Side Effect) is caused by Mefenamic acid (Compound) and Mefenamic acid (Compound) resembles Acetylsalicylic acid (Compound)
Esmolol (Compound) causes Agitation (Side Effect) and Agitation (Side Effect) is caused by Pantoprazole (Compound) and Pantoprazole may cause a minor interaction that can limit clinical effects when taken with Acetylsalicylic acid
Esmolol (Compound) resembles Metoprolol (Compound) and Metoprolol (Compound) binds CYP2C19 (Gene) and CYP2C19 (Gene) is bound by Acetylsalicylic acid (Compound)
Esmolol (Compound) resembles Bisoprolol (Compound) and Bisoprolol (Compound) causes Polyuria (Side Effect) and Polyuria (Side Effect) is caused by Acetylsalicylic acid (Compound)
Esmolol (Compound) resembles Acebutolol (Compound) and Acebutolol (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Acetylsalicylic acid (Compound)