DDInter1642 DDInter387
Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.
Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.
Cisplatin {u} (Compound) treats {v} (Disease) testicular cancer
Cisplatin {u} (Compound) binds {v} (Gene) SLC31A2
Cisplatin {u} (Compound) is included by {v} (Pharmacologic Class) Platinum-containing Compounds
Cisplatin {u} (Compound) causes {v} (Side Effect) Anaphylactic shock
Cisplatin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Lithium carbonate
Cisplatin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Grepafloxacin
Cisplatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clostridium tetani toxoid antigen (formaldehyde inactivated)
Cisplatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Alefacept
Cisplatin {u} may lead to a major life threatening interaction when taken with {v} Iothalamic acid
Cisplatin {u} may lead to a major life threatening interaction when taken with {v} Cladribine
Cisplatin (Compound) treats testicular cancer (Disease)
Cisplatin (Compound) binds SLC31A2 (Gene)
Cisplatin (Compound) is included by Platinum-containing Compounds (Pharmacologic Class)
Cisplatin (Compound) causes Anaphylactic shock (Side Effect)
Cisplatin may cause a minor interaction that can limit clinical effects when taken with Lithium carbonate
Cisplatin may cause a minor interaction that can limit clinical effects when taken with Grepafloxacin
Cisplatin may cause a moderate interaction that could exacerbate diseases when taken with Clostridium tetani toxoid antigen (formaldehyde inactivated)
Cisplatin may cause a moderate interaction that could exacerbate diseases when taken with Alefacept
Cisplatin may lead to a major life threatening interaction when taken with Iothalamic acid
Cisplatin may lead to a major life threatening interaction when taken with Cladribine