DDInter458 DDInter179
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus _Beauveria nivea_. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Cyclosporine {u} (Compound) downregulates {v} (Gene) KIF20A
KIF20A {u} (Gene) is downregulated by {v} (Compound) Bendroflumethiazide
Cyclosporine {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Bendroflumethiazide
Cyclosporine {u} (Compound) downregulates {v} (Gene) KIF20A
KIF20A {u} (Gene) is downregulated by {v} (Compound) Irinotecan
Irinotecan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Bendroflumethiazide
Cyclosporine {u} (Compound) downregulates {v} (Gene) MTERF3
MTERF3 {u} (Gene) is downregulated by {v} (Compound) Treprostinil
Treprostinil {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Bendroflumethiazide
Cyclosporine {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Hydrochlorothiazide
Hydrochlorothiazide {u} (Compound) resembles {v} (Compound) Bendroflumethiazide
Cyclosporine {u} (Compound) binds {v} (Gene) SLC22A6
SLC22A6 {u} (Gene) is bound by {v} (Compound) Hydrochlorothiazide
Hydrochlorothiazide {u} (Compound) resembles {v} (Compound) Bendroflumethiazide
Cyclosporine {u} (Compound) causes {v} (Side Effect) Urine output increased
Urine output increased {u} (Side Effect) is caused by {v} (Compound) Dapagliflozin
Dapagliflozin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Bendroflumethiazide
Cyclosporine {u} (Compound) causes {v} (Side Effect) Gout
Gout {u} (Side Effect) is caused by {v} (Compound) Pantoprazole
Pantoprazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Bendroflumethiazide
Cyclosporine {u} (Compound) upregulates {v} (Gene) CCDC92
CCDC92 {u} (Gene) is upregulated by {v} (Compound) Hydrochlorothiazide
Hydrochlorothiazide {u} (Compound) resembles {v} (Compound) Bendroflumethiazide
Cyclosporine {u} (Compound) binds {v} (Gene) SLC22A6
SLC22A6 {u} (Gene) is bound by {v} (Compound) Cyclothiazide
Cyclothiazide {u} (Compound) resembles {v} (Compound) Bendroflumethiazide
Cyclosporine (Compound) downregulates KIF20A (Gene) and KIF20A (Gene) is downregulated by Bendroflumethiazide (Compound)
Cyclosporine (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Bendroflumethiazide (Compound)
Cyclosporine (Compound) downregulates KIF20A (Gene) and KIF20A (Gene) is downregulated by Irinotecan (Compound) and Irinotecan may cause a moderate interaction that could exacerbate diseases when taken with Bendroflumethiazide
Cyclosporine (Compound) downregulates MTERF3 (Gene) and MTERF3 (Gene) is downregulated by Treprostinil (Compound) and Treprostinil may cause a moderate interaction that could exacerbate diseases when taken with Bendroflumethiazide
Cyclosporine (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Hydrochlorothiazide (Compound) and Hydrochlorothiazide (Compound) resembles Bendroflumethiazide (Compound)
Cyclosporine (Compound) binds SLC22A6 (Gene) and SLC22A6 (Gene) is bound by Hydrochlorothiazide (Compound) and Hydrochlorothiazide (Compound) resembles Bendroflumethiazide (Compound)
Cyclosporine (Compound) causes Urine output increased (Side Effect) and Urine output increased (Side Effect) is caused by Dapagliflozin (Compound) and Dapagliflozin may cause a moderate interaction that could exacerbate diseases when taken with Bendroflumethiazide
Cyclosporine (Compound) causes Gout (Side Effect) and Gout (Side Effect) is caused by Pantoprazole (Compound) and Pantoprazole may cause a moderate interaction that could exacerbate diseases when taken with Bendroflumethiazide
Cyclosporine (Compound) upregulates CCDC92 (Gene) and CCDC92 (Gene) is upregulated by Hydrochlorothiazide (Compound) and Hydrochlorothiazide (Compound) resembles Bendroflumethiazide (Compound)
Cyclosporine (Compound) binds SLC22A6 (Gene) and SLC22A6 (Gene) is bound by Cyclothiazide (Compound) and Cyclothiazide (Compound) resembles Bendroflumethiazide (Compound)