DDInter1956 DDInter1119
A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the elongation of DNA chains, thus resulting in the termination of viral DNA growth. The compound is a potent inhibitor of HIV replication at low concentrations, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Its principal toxic side effect is axonal degeneration resulting in peripheral neuropathy.
Magnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.
Zalcitabine {u} (Compound) causes {v} (Side Effect) Photophobia
Photophobia {u} (Side Effect) is caused by {v} (Compound) Lisinopril
Lisinopril {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium oxide
Zalcitabine {u} (Compound) causes {v} (Side Effect) Somnolence
Somnolence {u} (Side Effect) is caused by {v} (Compound) Nebivolol
Nebivolol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium oxide
Zalcitabine {u} (Compound) causes {v} (Side Effect) Haemoptysis
Haemoptysis {u} (Side Effect) is caused by {v} (Compound) Sparfloxacin
Sparfloxacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Magnesium oxide
Zalcitabine {u} (Compound) causes {v} (Side Effect) Photophobia
Photophobia {u} (Side Effect) is caused by {v} (Compound) Hydroxychloroquine
Hydroxychloroquine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Magnesium oxide
Zalcitabine {u} (Compound) causes {v} (Side Effect) Blood creatinine increased
Blood creatinine increased {u} (Side Effect) is caused by {v} (Compound) Dolutegravir
Dolutegravir {u} may lead to a major life threatening interaction when taken with {v} Magnesium oxide
Zalcitabine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Thioridazine
Thioridazine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium oxide
Zalcitabine {u} (Compound) upregulates {v} (Gene) TRAPPC6A
TRAPPC6A {u} (Gene) is upregulated by {v} (Compound) Thioridazine
Thioridazine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium oxide
Zalcitabine {u} (Compound) downregulates {v} (Gene) PCNA
PCNA {u} (Gene) is downregulated by {v} (Compound) Thioridazine
Thioridazine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium oxide
Zalcitabine {u} (Compound) upregulates {v} (Gene) TRAPPC6A
TRAPPC6A {u} (Gene) is upregulated by {v} (Compound) Ponatinib
Ponatinib {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium oxide
Zalcitabine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Nebivolol
Nebivolol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium oxide
Zalcitabine (Compound) causes Photophobia (Side Effect) and Photophobia (Side Effect) is caused by Lisinopril (Compound) and Lisinopril may cause a minor interaction that can limit clinical effects when taken with Magnesium oxide
Zalcitabine (Compound) causes Somnolence (Side Effect) and Somnolence (Side Effect) is caused by Nebivolol (Compound) and Nebivolol may cause a minor interaction that can limit clinical effects when taken with Magnesium oxide
Zalcitabine (Compound) causes Haemoptysis (Side Effect) and Haemoptysis (Side Effect) is caused by Sparfloxacin (Compound) and Sparfloxacin may cause a moderate interaction that could exacerbate diseases when taken with Magnesium oxide
Zalcitabine (Compound) causes Photophobia (Side Effect) and Photophobia (Side Effect) is caused by Hydroxychloroquine (Compound) and Hydroxychloroquine may cause a moderate interaction that could exacerbate diseases when taken with Magnesium oxide
Zalcitabine (Compound) causes Blood creatinine increased (Side Effect) and Blood creatinine increased (Side Effect) is caused by Dolutegravir (Compound) and Dolutegravir may lead to a major life threatening interaction when taken with Magnesium oxide
Zalcitabine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Thioridazine (Compound) and Thioridazine may cause a minor interaction that can limit clinical effects when taken with Magnesium oxide
Zalcitabine (Compound) upregulates TRAPPC6A (Gene) and TRAPPC6A (Gene) is upregulated by Thioridazine (Compound) and Thioridazine may cause a minor interaction that can limit clinical effects when taken with Magnesium oxide
Zalcitabine (Compound) downregulates PCNA (Gene) and PCNA (Gene) is downregulated by Thioridazine (Compound) and Thioridazine may cause a minor interaction that can limit clinical effects when taken with Magnesium oxide
Zalcitabine (Compound) upregulates TRAPPC6A (Gene) and TRAPPC6A (Gene) is upregulated by Ponatinib (Compound) and Ponatinib may cause a minor interaction that can limit clinical effects when taken with Magnesium oxide
Zalcitabine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Nebivolol (Compound) and Nebivolol may cause a minor interaction that can limit clinical effects when taken with Magnesium oxide