DDInter350 DDInter85
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.
Chlorambucil {u} (Compound) causes {v} (Side Effect) Toxic epidermal necrolysis
Toxic epidermal necrolysis {u} (Side Effect) is caused by {v} (Compound) Amphotericin B
Chlorambucil {u} (Compound) resembles {v} (Compound) Melphalan
Melphalan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amphotericin B
Chlorambucil {u} (Compound) causes {v} (Side Effect) Toxic epidermal necrolysis
Toxic epidermal necrolysis {u} (Side Effect) is caused by {v} (Compound) Voriconazole
Voriconazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Amphotericin B
Chlorambucil {u} (Compound) causes {v} (Side Effect) Hepatotoxicity
Hepatotoxicity {u} (Side Effect) is caused by {v} (Compound) Methotrexate
Methotrexate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amphotericin B
Chlorambucil {u} (Compound) causes {v} (Side Effect) Hypersensitivity
Hypersensitivity {u} (Side Effect) is caused by {v} (Compound) Natamycin
Natamycin {u} (Compound) resembles {v} (Compound) Amphotericin B
Chlorambucil {u} (Compound) treats {v} (Disease) ovarian cancer
ovarian cancer {u} (Disease) is treated by {v} (Compound) Melphalan
Melphalan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amphotericin B
Chlorambucil {u} (Compound) resembles {v} (Compound) Melphalan
Melphalan {u} (Compound) causes {v} (Side Effect) Bronchospasm
Bronchospasm {u} (Side Effect) is caused by {v} (Compound) Amphotericin B
Chlorambucil {u} (Compound) causes {v} (Side Effect) Nephrotic syndrome
Nephrotic syndrome {u} (Side Effect) is caused by {v} (Compound) Esomeprazole
Esomeprazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amphotericin B
Chlorambucil {u} (Compound) causes {v} (Side Effect) Mouth ulceration
Mouth ulceration {u} (Side Effect) is caused by {v} (Compound) Miconazole
Miconazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Amphotericin B
Chlorambucil {u} (Compound) treats {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is treated by {v} (Compound) Clofarabine
Clofarabine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amphotericin B
Chlorambucil (Compound) causes Toxic epidermal necrolysis (Side Effect) and Toxic epidermal necrolysis (Side Effect) is caused by Amphotericin B (Compound)
Chlorambucil (Compound) resembles Melphalan (Compound) and Melphalan may cause a moderate interaction that could exacerbate diseases when taken with Amphotericin B
Chlorambucil (Compound) causes Toxic epidermal necrolysis (Side Effect) and Toxic epidermal necrolysis (Side Effect) is caused by Voriconazole (Compound) and Voriconazole may cause a minor interaction that can limit clinical effects when taken with Amphotericin B
Chlorambucil (Compound) causes Hepatotoxicity (Side Effect) and Hepatotoxicity (Side Effect) is caused by Methotrexate (Compound) and Methotrexate may cause a moderate interaction that could exacerbate diseases when taken with Amphotericin B
Chlorambucil (Compound) causes Hypersensitivity (Side Effect) and Hypersensitivity (Side Effect) is caused by Natamycin (Compound) and Natamycin (Compound) resembles Amphotericin B (Compound)
Chlorambucil (Compound) treats ovarian cancer (Disease) and ovarian cancer (Disease) is treated by Melphalan (Compound) and Melphalan may cause a moderate interaction that could exacerbate diseases when taken with Amphotericin B
Chlorambucil (Compound) resembles Melphalan (Compound) and Melphalan (Compound) causes Bronchospasm (Side Effect) and Bronchospasm (Side Effect) is caused by Amphotericin B (Compound)
Chlorambucil (Compound) causes Nephrotic syndrome (Side Effect) and Nephrotic syndrome (Side Effect) is caused by Esomeprazole (Compound) and Esomeprazole may cause a moderate interaction that could exacerbate diseases when taken with Amphotericin B
Chlorambucil (Compound) causes Mouth ulceration (Side Effect) and Mouth ulceration (Side Effect) is caused by Miconazole (Compound) and Miconazole may cause a minor interaction that can limit clinical effects when taken with Amphotericin B
Chlorambucil (Compound) treats hematologic cancer (Disease) and hematologic cancer (Disease) is treated by Clofarabine (Compound) and Clofarabine may cause a moderate interaction that could exacerbate diseases when taken with Amphotericin B