DDInter1448 DDInter981
Phentolamine is a reversible, non-selective alpha-adrenergic blocker that induces vasodilation. While initially introduced to the market for the treatment of hypertension, this clinical use was halted due to cardiovascular and gastrointestinal adverse effects with the prolonged use of large oral doses of phentolamine.[A261781, A261786] It has several therapeutic uses, including the treatment of hypertensive episodes, prevention of norepinephrine-induced extravasation, diagnosis of pheochromocytoma, reversal of soft-tissue anesthesia, and treatment of pharmacologically-induced mydriasis.[L48420, L48415, L48390] Phentolamine is administered intravenously, intramuscularly, submucosally, and topically.
Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor. It is used in the treatment of major depression, dysthymic disorder, atypical disorder, panic disorder and the phobic disorders. It was first introduced by Roche pharmaceuticals, further developed by Validus pharms Inc and first FDA approved as a prescription drug on July 1st, 1959.
Phentolamine {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Isocarboxazid
Phentolamine {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Lacosamide
Lacosamide {u} (Compound) resembles {v} (Compound) Isocarboxazid
Phentolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenelzine
Phenelzine {u} (Compound) resembles {v} (Compound) Phenacemide
Phenacemide {u} (Compound) resembles {v} (Compound) Isocarboxazid
Phentolamine {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Metamfetamine
Metamfetamine {u} (Compound) resembles {v} (Compound) Isocarboxazid
Phentolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Guanfacine
Guanfacine {u} (Compound) resembles {v} (Compound) Phenacemide
Phenacemide {u} (Compound) resembles {v} (Compound) Isocarboxazid
Phentolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nabilone
Nabilone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenacemide
Phenacemide {u} (Compound) resembles {v} (Compound) Isocarboxazid
Phentolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Guanfacine
Guanfacine {u} (Compound) causes {v} (Side Effect) Somnolence
Somnolence {u} (Side Effect) is caused by {v} (Compound) Isocarboxazid
Phentolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenelzine
Phenelzine {u} (Compound) resembles {v} (Compound) Benzyl alcohol
Benzyl alcohol {u} (Compound) resembles {v} (Compound) Isocarboxazid
Phentolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Diphenhydramine
Diphenhydramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenacemide
Phenacemide {u} (Compound) resembles {v} (Compound) Isocarboxazid
Phentolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nabilone
Nabilone {u} (Compound) causes {v} (Side Effect) Amblyopia
Amblyopia {u} (Side Effect) is caused by {v} (Compound) Isocarboxazid
Phentolamine (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Isocarboxazid (Compound)
Phentolamine (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Lacosamide (Compound) and Lacosamide (Compound) resembles Isocarboxazid (Compound)
Phentolamine may cause a moderate interaction that could exacerbate diseases when taken with Phenelzine and Phenelzine (Compound) resembles Phenacemide (Compound) and Phenacemide (Compound) resembles Isocarboxazid (Compound)
Phentolamine (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Metamfetamine (Compound) and Metamfetamine (Compound) resembles Isocarboxazid (Compound)
Phentolamine may cause a moderate interaction that could exacerbate diseases when taken with Guanfacine and Guanfacine (Compound) resembles Phenacemide (Compound) and Phenacemide (Compound) resembles Isocarboxazid (Compound)
Phentolamine may cause a moderate interaction that could exacerbate diseases when taken with Nabilone and Nabilone may cause a moderate interaction that could exacerbate diseases when taken with Phenacemide and Phenacemide (Compound) resembles Isocarboxazid (Compound)
Phentolamine may cause a moderate interaction that could exacerbate diseases when taken with Guanfacine and Guanfacine (Compound) causes Somnolence (Side Effect) and Somnolence (Side Effect) is caused by Isocarboxazid (Compound)
Phentolamine may cause a moderate interaction that could exacerbate diseases when taken with Phenelzine and Phenelzine (Compound) resembles Benzyl alcohol (Compound) and Benzyl alcohol (Compound) resembles Isocarboxazid (Compound)
Phentolamine may cause a moderate interaction that could exacerbate diseases when taken with Diphenhydramine and Diphenhydramine may cause a moderate interaction that could exacerbate diseases when taken with Phenacemide and Phenacemide (Compound) resembles Isocarboxazid (Compound)
Phentolamine may cause a moderate interaction that could exacerbate diseases when taken with Nabilone and Nabilone (Compound) causes Amblyopia (Side Effect) and Amblyopia (Side Effect) is caused by Isocarboxazid (Compound)