DDInter553 DDInter1676
A cardiac glycoside sometimes used in place of digoxin. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting. (From Martindale, The Extra Pharmacopoeia, 30th ed, p665)
Siponimod, also known as _Mayzent_, by Novartis, is a new drug formulated for the management of Multiple Sclerosis (MS). It was approved by the FDA on March 26, 2019 and by Health Canada on February 20, 2020. This drug is considered a _sphingosine-1-phosphate (S1P) receptor modulator_ and is thought to play a role in suppressing the central nervous system inflammation that is associated with MS [FDA label]. Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system that is chronic and inflammatory, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of life. Symptoms may include but are not limited to fatigue, gait changes, bowel or bladder dysfunction, abnormal muscle twitching, vision disturbance, and depressing or mood swings. MS is one of the most common causes of neurological disability in young adults and is found to occur more frequently in women than in men.[A176474,L5792]
Digitoxin {u} (Compound) resembles {v} (Compound) Digoxin
Digitoxin {u} (Compound) resembles {v} (Compound) Deslanoside
Digitoxin {u} (Compound) binds {v} (Gene) CYP3A4
Digitoxin {u} (Compound) upregulates {v} (Gene) PTBP2
Digitoxin {u} (Compound) downregulates {v} (Gene) ZDHHC6
Digitoxin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium oxide
Digitoxin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium hydroxide
Digitoxin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Teriparatide
Digitoxin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pseudoephedrine
Digitoxin {u} may lead to a major life threatening interaction when taken with {v} Calcium gluconate
Digitoxin (Compound) resembles Digoxin (Compound)
Digitoxin (Compound) resembles Deslanoside (Compound)
Digitoxin (Compound) binds CYP3A4 (Gene)
Digitoxin (Compound) upregulates PTBP2 (Gene)
Digitoxin (Compound) downregulates ZDHHC6 (Gene)
Digitoxin may cause a minor interaction that can limit clinical effects when taken with Magnesium oxide
Digitoxin may cause a minor interaction that can limit clinical effects when taken with Magnesium hydroxide
Digitoxin may cause a moderate interaction that could exacerbate diseases when taken with Teriparatide
Digitoxin may cause a moderate interaction that could exacerbate diseases when taken with Pseudoephedrine
Digitoxin may lead to a major life threatening interaction when taken with Calcium gluconate