DDInter1340 DDInter1360
Originally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class, and its approval was followed by the formulation of many other proton pump inhibitor drugs. Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults [FDA label].
Oxcarbazepine is an anti-epileptic medication used in the treatment of partial onset seizures that was first approved for use in the United States in 2000.[L8627,L8630,L8633] It is a structural derivative of [carbamazepine] and exerts a majority of its activity via a pharmacologically active metabolite, MHD, which exists as a racemate in the blood - a pro-drug of the more active (S)-enantiomer is also marketed as a separate anti-epileptic under the name [eslicarbazepine]. Compared to other anti-epileptic drugs, which are generally metabolized via the cytochrome P450 system, oxcarbazepine has a reduced propensity for involvement in drug-drug interactions owing to its primarily reductive metabolism.
Omeprazole {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Oxcarbazepine
Omeprazole {u} (Compound) causes {v} (Side Effect) Multiple fractures
Multiple fractures {u} (Side Effect) is caused by {v} (Compound) Oxcarbazepine
Omeprazole {u} (Compound) resembles {v} (Compound) Lansoprazole
Lansoprazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxcarbazepine
Omeprazole {u} (Compound) resembles {v} (Compound) Pantoprazole
Pantoprazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxcarbazepine
Omeprazole {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Oxcarbazepine
Omeprazole {u} (Compound) causes {v} (Side Effect) Multiple fractures
Multiple fractures {u} (Side Effect) is caused by {v} (Compound) Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Oxcarbazepine
Omeprazole {u} (Compound) causes {v} (Side Effect) Hot flush
Hot flush {u} (Side Effect) is caused by {v} (Compound) Doxepin
Doxepin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxcarbazepine
Omeprazole {u} (Compound) causes {v} (Side Effect) Ulcerative stomatitis
Ulcerative stomatitis {u} (Side Effect) is caused by {v} (Compound) Lansoprazole
Lansoprazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxcarbazepine
Omeprazole {u} (Compound) causes {v} (Side Effect) Apathy
Apathy {u} (Side Effect) is caused by {v} (Compound) Clobazam
Clobazam {u} (Compound) resembles {v} (Compound) Oxcarbazepine
Omeprazole {u} (Compound) causes {v} (Side Effect) Encephalopathy
Encephalopathy {u} (Side Effect) is caused by {v} (Compound) Bortezomib
Bortezomib {u} may cause a minor interaction that can limit clinical effects when taken with {v} Oxcarbazepine
Omeprazole (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Oxcarbazepine (Compound)
Omeprazole (Compound) causes Multiple fractures (Side Effect) and Multiple fractures (Side Effect) is caused by Oxcarbazepine (Compound)
Omeprazole (Compound) resembles Lansoprazole (Compound) and Lansoprazole may cause a moderate interaction that could exacerbate diseases when taken with Oxcarbazepine
Omeprazole (Compound) resembles Pantoprazole (Compound) and Pantoprazole may cause a moderate interaction that could exacerbate diseases when taken with Oxcarbazepine
Omeprazole (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Indapamide (Compound) and Indapamide (Compound) resembles Oxcarbazepine (Compound)
Omeprazole (Compound) causes Multiple fractures (Side Effect) and Multiple fractures (Side Effect) is caused by Indapamide (Compound) and Indapamide (Compound) resembles Oxcarbazepine (Compound)
Omeprazole (Compound) causes Hot flush (Side Effect) and Hot flush (Side Effect) is caused by Doxepin (Compound) and Doxepin may cause a moderate interaction that could exacerbate diseases when taken with Oxcarbazepine
Omeprazole (Compound) causes Ulcerative stomatitis (Side Effect) and Ulcerative stomatitis (Side Effect) is caused by Lansoprazole (Compound) and Lansoprazole may cause a moderate interaction that could exacerbate diseases when taken with Oxcarbazepine
Omeprazole (Compound) causes Apathy (Side Effect) and Apathy (Side Effect) is caused by Clobazam (Compound) and Clobazam (Compound) resembles Oxcarbazepine (Compound)
Omeprazole (Compound) causes Encephalopathy (Side Effect) and Encephalopathy (Side Effect) is caused by Bortezomib (Compound) and Bortezomib may cause a minor interaction that can limit clinical effects when taken with Oxcarbazepine