DDInter350 DDInter1961
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
A dideoxynucleoside compound in which the 3&#39;-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia. [PubChem]
Chlorambucil {u} (Compound) causes {v} (Side Effect) Tremor
Tremor {u} (Side Effect) is caused by {v} (Compound) Zidovudine
Chlorambucil {u} (Compound) resembles {v} (Compound) Melphalan
Melphalan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Zidovudine
Chlorambucil {u} (Compound) causes {v} (Side Effect) Tremor
Tremor {u} (Side Effect) is caused by {v} (Compound) Acyclovir
Acyclovir {u} may cause a minor interaction that can limit clinical effects when taken with {v} Zidovudine
Chlorambucil {u} (Compound) causes {v} (Side Effect) Anorexia
Anorexia {u} (Side Effect) is caused by {v} (Compound) Stavudine
Stavudine {u} (Compound) resembles {v} (Compound) Zidovudine
Chlorambucil {u} (Compound) causes {v} (Side Effect) Cystitis noninfective
Cystitis noninfective {u} (Side Effect) is caused by {v} (Compound) Cabazitaxel
Cabazitaxel {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Zidovudine
Chlorambucil {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Trifluridine
Trifluridine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Zidovudine
Chlorambucil {u} (Compound) treats {v} (Disease) ovarian cancer
ovarian cancer {u} (Disease) downregulates {v} (Gene) TUBA1A
TUBA1A {u} (Gene) is downregulated by {v} (Compound) Zidovudine
Chlorambucil {u} (Compound) resembles {v} (Compound) Melphalan
Melphalan {u} (Compound) causes {v} (Side Effect) Anorexia
Anorexia {u} (Side Effect) is caused by {v} (Compound) Zidovudine
Chlorambucil {u} (Compound) treats {v} (Disease) ovarian cancer
ovarian cancer {u} (Disease) is associated with {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Zidovudine
Chlorambucil {u} (Compound) treats {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Paclitaxel
Paclitaxel {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Zidovudine
Chlorambucil (Compound) causes Tremor (Side Effect) and Tremor (Side Effect) is caused by Zidovudine (Compound)
Chlorambucil (Compound) resembles Melphalan (Compound) and Melphalan may cause a moderate interaction that could exacerbate diseases when taken with Zidovudine
Chlorambucil (Compound) causes Tremor (Side Effect) and Tremor (Side Effect) is caused by Acyclovir (Compound) and Acyclovir may cause a minor interaction that can limit clinical effects when taken with Zidovudine
Chlorambucil (Compound) causes Anorexia (Side Effect) and Anorexia (Side Effect) is caused by Stavudine (Compound) and Stavudine (Compound) resembles Zidovudine (Compound)
Chlorambucil (Compound) causes Cystitis noninfective (Side Effect) and Cystitis noninfective (Side Effect) is caused by Cabazitaxel (Compound) and Cabazitaxel may cause a moderate interaction that could exacerbate diseases when taken with Zidovudine
Chlorambucil (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Trifluridine (Compound) and Trifluridine may cause a moderate interaction that could exacerbate diseases when taken with Zidovudine
Chlorambucil (Compound) treats ovarian cancer (Disease) and ovarian cancer (Disease) downregulates TUBA1A (Gene) and TUBA1A (Gene) is downregulated by Zidovudine (Compound)
Chlorambucil (Compound) resembles Melphalan (Compound) and Melphalan (Compound) causes Anorexia (Side Effect) and Anorexia (Side Effect) is caused by Zidovudine (Compound)
Chlorambucil (Compound) treats ovarian cancer (Disease) and ovarian cancer (Disease) is associated with ABCB1 (Gene) and ABCB1 (Gene) is bound by Zidovudine (Compound)
Chlorambucil (Compound) treats breast cancer (Disease) and breast cancer (Disease) is treated by Paclitaxel (Compound) and Paclitaxel may cause a moderate interaction that could exacerbate diseases when taken with Zidovudine