DDInter1447 DDInter1867
Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug.[A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine. Phentermine has not been reported an addictive potential which allows this agent to be classified under the Schedule IV drugs (low abuse potential). Phentermine was FDA approved for short-term weight management in 1959 and it became widely used in 1960. This initial product, formed by the combination of phentermine with [fenfluramine] and [dexfenfluramine] was discontinued after finding several reports of abnormal valves in nearly 30% of the consumers.[A174376, T403] Later on, phentermine was approved alone and in combination with topiramate in 2012 as a new alternative that required lower doses of phentermine to
A phenothiazine used as an antipsychotic agent and as an antiemetic.
Phentermine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Perphenazine
Perphenazine {u} (Compound) resembles {v} (Compound) Triflupromazine
Phentermine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Perphenazine
Perphenazine {u} (Compound) resembles {v} (Compound) Pipotiazine
Pipotiazine {u} (Compound) resembles {v} (Compound) Triflupromazine
Phentermine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Pipotiazine
Pipotiazine {u} (Compound) resembles {v} (Compound) Triflupromazine
Phentermine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Perphenazine
Perphenazine {u} (Compound) resembles {v} (Compound) Mequitazine
Mequitazine {u} (Compound) resembles {v} (Compound) Triflupromazine
Phentermine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methdilazine
Methdilazine {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Perphenazine
Perphenazine {u} (Compound) resembles {v} (Compound) Triflupromazine
Phentermine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clomipramine
Clomipramine {u} (Compound) resembles {v} (Compound) Desipramine
Desipramine {u} (Compound) resembles {v} (Compound) Triflupromazine
Phentermine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Desipramine
Desipramine {u} (Compound) resembles {v} (Compound) Triflupromazine
Phentermine {u} may lead to a major life threatening interaction when taken with {v} Benzphetamine
Benzphetamine {u} (Compound) resembles {v} (Compound) Ethopropazine
Ethopropazine {u} (Compound) resembles {v} (Compound) Triflupromazine
Phentermine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methadone
Methadone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methdilazine
Methdilazine {u} (Compound) resembles {v} (Compound) Triflupromazine
Phentermine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Perphenazine
Perphenazine {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methdilazine
Methdilazine {u} (Compound) resembles {v} (Compound) Triflupromazine
Phentermine may cause a moderate interaction that could exacerbate diseases when taken with Perphenazine and Perphenazine (Compound) resembles Triflupromazine (Compound)
Phentermine may cause a moderate interaction that could exacerbate diseases when taken with Perphenazine and Perphenazine (Compound) resembles Pipotiazine (Compound) and Pipotiazine (Compound) resembles Triflupromazine (Compound)
Phentermine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Pipotiazine (Compound) and Pipotiazine (Compound) resembles Triflupromazine (Compound)
Phentermine may cause a moderate interaction that could exacerbate diseases when taken with Perphenazine and Perphenazine (Compound) resembles Mequitazine (Compound) and Mequitazine (Compound) resembles Triflupromazine (Compound)
Phentermine may cause a moderate interaction that could exacerbate diseases when taken with Methdilazine and Methdilazine (Compound) resembles Perphenazine (Compound) and Methdilazine may cause a moderate interaction that could exacerbate diseases when taken with Perphenazine and Perphenazine (Compound) resembles Triflupromazine (Compound)
Phentermine may cause a moderate interaction that could exacerbate diseases when taken with Clomipramine and Clomipramine (Compound) resembles Desipramine (Compound) and Desipramine (Compound) resembles Triflupromazine (Compound)
Phentermine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Desipramine (Compound) and Desipramine (Compound) resembles Triflupromazine (Compound)
Phentermine may lead to a major life threatening interaction when taken with Benzphetamine and Benzphetamine (Compound) resembles Ethopropazine (Compound) and Ethopropazine (Compound) resembles Triflupromazine (Compound)
Phentermine may cause a moderate interaction that could exacerbate diseases when taken with Methadone and Methadone may cause a moderate interaction that could exacerbate diseases when taken with Methdilazine and Methdilazine (Compound) resembles Triflupromazine (Compound)
Phentermine may cause a moderate interaction that could exacerbate diseases when taken with Perphenazine and Perphenazine (Compound) resembles Methdilazine (Compound) and Perphenazine may cause a moderate interaction that could exacerbate diseases when taken with Methdilazine and Methdilazine (Compound) resembles Triflupromazine (Compound)