DDInter790 DDInter1713
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of water from the body. Furosemide has a fast onset and short duration of action and has been used safely and effectively in both pediatric and adult patients. The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential. In addition to oral formulations, the solution for intravenous and intramuscular administration is also available, which is typically limited to patients who are unable to take oral medication or for patients in emergency clinical situations.
Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and used in practice in the 1940s.[A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of streptomycin and its antibacterial activity.[A233325,A232294] Although streptomycin was the first antibiotic determined to be effective against mycobacterium tuberculosis, it has fallen out of favor due to resistance and is now primarily used as adjunctive treatment in cases of multi-drug resistant tuberculosis.
Furosemide {u} (Compound) binds {v} (Gene) SLC22A6
SLC22A6 {u} (Gene) is bound by {v} (Compound) Streptomycin
Furosemide {u} (Compound) causes {v} (Side Effect) Renal failure
Renal failure {u} (Side Effect) is caused by {v} (Compound) Streptomycin
Furosemide {u} (Compound) binds {v} (Gene) SLC22A6
SLC22A6 {u} (Gene) is bound by {v} (Compound) Piroxicam
Piroxicam {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Streptomycin
Furosemide {u} (Compound) causes {v} (Side Effect) Renal failure
Renal failure {u} (Side Effect) is caused by {v} (Compound) Ceftaroline fosamil
Ceftaroline fosamil {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Streptomycin
Furosemide {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Amikacin
Amikacin {u} (Compound) resembles {v} (Compound) Streptomycin
Furosemide {u} (Compound) causes {v} (Side Effect) Urticaria
Urticaria {u} (Side Effect) is caused by {v} (Compound) Lidocaine
Lidocaine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Streptomycin
Furosemide {u} (Compound) causes {v} (Side Effect) Dermatitis exfoliative
Dermatitis exfoliative {u} (Side Effect) is caused by {v} (Compound) Etodolac
Etodolac {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Streptomycin
Furosemide {u} (Compound) causes {v} (Side Effect) Ototoxicity
Ototoxicity {u} (Side Effect) is caused by {v} (Compound) Capreomycin
Capreomycin {u} may lead to a major life threatening interaction when taken with {v} Streptomycin
Furosemide {u} (Compound) causes {v} (Side Effect) Ototoxicity
Ototoxicity {u} (Side Effect) is caused by {v} (Compound) Kanamycin
Kanamycin {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Streptomycin
Furosemide {u} (Compound) resembles {v} (Compound) Bumetanide
Bumetanide {u} (Compound) binds {v} (Gene) SLC22A6
SLC22A6 {u} (Gene) is bound by {v} (Compound) Streptomycin
Furosemide (Compound) binds SLC22A6 (Gene) and SLC22A6 (Gene) is bound by Streptomycin (Compound)
Furosemide (Compound) causes Renal failure (Side Effect) and Renal failure (Side Effect) is caused by Streptomycin (Compound)
Furosemide (Compound) binds SLC22A6 (Gene) and SLC22A6 (Gene) is bound by Piroxicam (Compound) and Piroxicam may cause a moderate interaction that could exacerbate diseases when taken with Streptomycin
Furosemide (Compound) causes Renal failure (Side Effect) and Renal failure (Side Effect) is caused by Ceftaroline fosamil (Compound) and Ceftaroline fosamil may cause a moderate interaction that could exacerbate diseases when taken with Streptomycin
Furosemide (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Amikacin (Compound) and Amikacin (Compound) resembles Streptomycin (Compound)
Furosemide (Compound) causes Urticaria (Side Effect) and Urticaria (Side Effect) is caused by Lidocaine (Compound) and Lidocaine may cause a minor interaction that can limit clinical effects when taken with Streptomycin
Furosemide (Compound) causes Dermatitis exfoliative (Side Effect) and Dermatitis exfoliative (Side Effect) is caused by Etodolac (Compound) and Etodolac may cause a moderate interaction that could exacerbate diseases when taken with Streptomycin
Furosemide (Compound) causes Ototoxicity (Side Effect) and Ototoxicity (Side Effect) is caused by Capreomycin (Compound) and Capreomycin may lead to a major life threatening interaction when taken with Streptomycin
Furosemide (Compound) causes Ototoxicity (Side Effect) and Ototoxicity (Side Effect) is caused by Kanamycin (Compound) and Kanamycin (Compound) resembles Streptomycin (Compound) and Kanamycin may cause a moderate interaction that could exacerbate diseases when taken with Streptomycin
Furosemide (Compound) resembles Bumetanide (Compound) and Bumetanide (Compound) binds SLC22A6 (Gene) and SLC22A6 (Gene) is bound by Streptomycin (Compound)