DDInter834 DDInter1610
Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. They are both quaternary ammonium compounds and long acting muscarinic antagonists. It is one of the most commonly prescribed anticholinergic medications.[A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the treatment of peptic ulcers.[A233570,L33090] Later research, taking advantage of the systemic distribution of muscarinic receptors through the body, found that glycopyrronium could also be used for reducing sweat gland, oral, airway, and gastric secretions; as well as reducing cardiac inhibitory reflexes; and reducing bronchoconstriction in COPD. Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications and is considered to have a wider therapeutic window than [tiotropium]. Glycopy
Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type. Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase.
Glycopyrronium {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pyridostigmine
Pyridostigmine {u} (Compound) resembles {v} (Compound) Rivastigmine
Glycopyrronium {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tapentadol
Tapentadol {u} (Compound) resembles {v} (Compound) Rivastigmine
Glycopyrronium {u} (Compound) causes {v} (Side Effect) Epistaxis
Epistaxis {u} (Side Effect) is caused by {v} (Compound) Rivastigmine
Glycopyrronium {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pyridostigmine
Pyridostigmine {u} (Compound) resembles {v} (Compound) Neostigmine
Neostigmine {u} (Compound) resembles {v} (Compound) Rivastigmine
Glycopyrronium {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tapentadol
Tapentadol {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Rivastigmine
Glycopyrronium {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Neostigmine
Neostigmine {u} (Compound) resembles {v} (Compound) Pyridostigmine
Pyridostigmine {u} (Compound) resembles {v} (Compound) Rivastigmine
Glycopyrronium {u} (Compound) causes {v} (Side Effect) Epistaxis
Epistaxis {u} (Side Effect) is caused by {v} (Compound) Pyridostigmine
Pyridostigmine {u} (Compound) resembles {v} (Compound) Rivastigmine
Glycopyrronium {u} (Compound) causes {v} (Side Effect) Pruritus
Pruritus {u} (Side Effect) is caused by {v} (Compound) Tapentadol
Tapentadol {u} (Compound) resembles {v} (Compound) Rivastigmine
Glycopyrronium {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mepenzolate
Mepenzolate {u} (Compound) upregulates {v} (Gene) WRB
WRB {u} (Gene) is upregulated by {v} (Compound) Rivastigmine
Glycopyrronium {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pyridostigmine
Pyridostigmine {u} (Compound) binds {v} (Gene) ACHE
ACHE {u} (Gene) is bound by {v} (Compound) Rivastigmine
Glycopyrronium may cause a moderate interaction that could exacerbate diseases when taken with Pyridostigmine and Pyridostigmine (Compound) resembles Rivastigmine (Compound)
Glycopyrronium may cause a moderate interaction that could exacerbate diseases when taken with Tapentadol and Tapentadol (Compound) resembles Rivastigmine (Compound)
Glycopyrronium (Compound) causes Epistaxis (Side Effect) and Epistaxis (Side Effect) is caused by Rivastigmine (Compound)
Glycopyrronium may cause a moderate interaction that could exacerbate diseases when taken with Pyridostigmine and Pyridostigmine (Compound) resembles Neostigmine (Compound) and Neostigmine (Compound) resembles Rivastigmine (Compound)
Glycopyrronium may cause a moderate interaction that could exacerbate diseases when taken with Tapentadol and Tapentadol (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Rivastigmine (Compound)
Glycopyrronium may cause a moderate interaction that could exacerbate diseases when taken with Neostigmine and Neostigmine (Compound) resembles Pyridostigmine (Compound) and Pyridostigmine (Compound) resembles Rivastigmine (Compound)
Glycopyrronium (Compound) causes Epistaxis (Side Effect) and Epistaxis (Side Effect) is caused by Pyridostigmine (Compound) and Pyridostigmine (Compound) resembles Rivastigmine (Compound)
Glycopyrronium (Compound) causes Pruritus (Side Effect) and Pruritus (Side Effect) is caused by Tapentadol (Compound) and Tapentadol (Compound) resembles Rivastigmine (Compound)
Glycopyrronium may cause a moderate interaction that could exacerbate diseases when taken with Mepenzolate and Mepenzolate (Compound) upregulates WRB (Gene) and WRB (Gene) is upregulated by Rivastigmine (Compound)
Glycopyrronium may cause a moderate interaction that could exacerbate diseases when taken with Pyridostigmine and Pyridostigmine (Compound) binds ACHE (Gene) and ACHE (Gene) is bound by Rivastigmine (Compound)