DDInter1074 DDInter1674
Liothyronine is a thyroidal hormone T3 which is normally produced by the thyroid gland in a ratio 4:1 when compared with T4: T3. Liothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine with bound iodine. The exogenous liothyronine product was developed by King Pharmaceuticals and FDA approved in 1956.
Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. It has a favourable safety profile as it is not systemically absorbed. Simethicone has been in use since the 1940s but was granted FDA approval in 1952.
Liothyronine {u} (Compound) resembles {v} (Compound) L-Tyrosine
Liothyronine {u} (Compound) treats {v} (Disease) hypothyroidism
Liothyronine {u} (Compound) binds {v} (Gene) SLCO4A1
Liothyronine {u} (Compound) upregulates {v} (Gene) TIPARP
Liothyronine {u} (Compound) is included by {v} (Pharmacologic Class) Triiodothyronine
Liothyronine {u} (Compound) causes {v} (Side Effect) Tachycardia
Liothyronine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Simvastatin
Liothyronine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Lovastatin
Liothyronine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amiodarone
Liothyronine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Calcium acetate
Liothyronine (Compound) resembles L-Tyrosine (Compound)
Liothyronine (Compound) treats hypothyroidism (Disease)
Liothyronine (Compound) binds SLCO4A1 (Gene)
Liothyronine (Compound) upregulates TIPARP (Gene)
Liothyronine (Compound) is included by Triiodothyronine (Pharmacologic Class)
Liothyronine (Compound) causes Tachycardia (Side Effect)
Liothyronine may cause a minor interaction that can limit clinical effects when taken with Simvastatin
Liothyronine may cause a minor interaction that can limit clinical effects when taken with Lovastatin
Liothyronine may cause a moderate interaction that could exacerbate diseases when taken with Amiodarone
Liothyronine may cause a moderate interaction that could exacerbate diseases when taken with Calcium acetate