DDInter350 DDInter1156
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
Chlorambucil {u} (Compound) treats {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is treated by {v} (Compound) Mercaptopurine
Chlorambucil {u} (Compound) causes {v} (Side Effect) Hypersensitivity
Hypersensitivity {u} (Side Effect) is caused by {v} (Compound) Mercaptopurine
Chlorambucil {u} (Compound) resembles {v} (Compound) Melphalan
Melphalan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mercaptopurine
Chlorambucil {u} (Compound) treats {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is treated by {v} (Compound) Methotrexate
Methotrexate {u} may cause a minor interaction that can limit clinical effects when taken with {v} Mercaptopurine
Chlorambucil {u} (Compound) causes {v} (Side Effect) Hypersensitivity
Hypersensitivity {u} (Side Effect) is caused by {v} (Compound) Trovafloxacin
Trovafloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Mercaptopurine
Chlorambucil {u} (Compound) causes {v} (Side Effect) Drug fever
Drug fever {u} (Side Effect) is caused by {v} (Compound) Trimethoprim
Trimethoprim {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mercaptopurine
Chlorambucil {u} (Compound) treats {v} (Disease) ovarian cancer
ovarian cancer {u} (Disease) is treated by {v} (Compound) Epirubicin
Epirubicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mercaptopurine
Chlorambucil {u} (Compound) resembles {v} (Compound) Melphalan
Melphalan {u} (Compound) treats {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is treated by {v} (Compound) Mercaptopurine
Chlorambucil {u} (Compound) causes {v} (Side Effect) Alopecia
Alopecia {u} (Side Effect) is caused by {v} (Compound) Sparfloxacin
Sparfloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Mercaptopurine
Chlorambucil {u} (Compound) treats {v} (Disease) breast cancer
breast cancer {u} (Disease) downregulates {v} (Gene) AOX1
AOX1 {u} (Gene) is bound by {v} (Compound) Mercaptopurine
Chlorambucil (Compound) treats hematologic cancer (Disease) and hematologic cancer (Disease) is treated by Mercaptopurine (Compound)
Chlorambucil (Compound) causes Hypersensitivity (Side Effect) and Hypersensitivity (Side Effect) is caused by Mercaptopurine (Compound)
Chlorambucil (Compound) resembles Melphalan (Compound) and Melphalan may cause a moderate interaction that could exacerbate diseases when taken with Mercaptopurine
Chlorambucil (Compound) treats hematologic cancer (Disease) and hematologic cancer (Disease) is treated by Methotrexate (Compound) and Methotrexate may cause a minor interaction that can limit clinical effects when taken with Mercaptopurine
Chlorambucil (Compound) causes Hypersensitivity (Side Effect) and Hypersensitivity (Side Effect) is caused by Trovafloxacin (Compound) and Trovafloxacin may cause a minor interaction that can limit clinical effects when taken with Mercaptopurine
Chlorambucil (Compound) causes Drug fever (Side Effect) and Drug fever (Side Effect) is caused by Trimethoprim (Compound) and Trimethoprim may cause a moderate interaction that could exacerbate diseases when taken with Mercaptopurine
Chlorambucil (Compound) treats ovarian cancer (Disease) and ovarian cancer (Disease) is treated by Epirubicin (Compound) and Epirubicin may cause a moderate interaction that could exacerbate diseases when taken with Mercaptopurine
Chlorambucil (Compound) resembles Melphalan (Compound) and Melphalan (Compound) treats hematologic cancer (Disease) and hematologic cancer (Disease) is treated by Mercaptopurine (Compound)
Chlorambucil (Compound) causes Alopecia (Side Effect) and Alopecia (Side Effect) is caused by Sparfloxacin (Compound) and Sparfloxacin may cause a minor interaction that can limit clinical effects when taken with Mercaptopurine
Chlorambucil (Compound) treats breast cancer (Disease) and breast cancer (Disease) downregulates AOX1 (Gene) and AOX1 (Gene) is bound by Mercaptopurine (Compound)