DDInter1156 DDInter178
An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
Bendamustine is a nitrogen mustard drug indicated for use in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed during or within six months of treatment with rituximab or a rituximab-containing regimen. Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases resulting in cell death. It is active against both active and quiescent cells, although the exact mechanism of action is unknown.
Mercaptopurine {u} (Compound) resembles {v} (Compound) Adenine
Mercaptopurine {u} (Compound) treats {v} (Disease) Crohn's disease
Mercaptopurine {u} (Compound) binds {v} (Gene) AOX1
Mercaptopurine {u} (Compound) causes {v} (Side Effect) Candida infection
Mercaptopurine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Trovafloxacin
Mercaptopurine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Sparfloxacin
Mercaptopurine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Warfarin
Mercaptopurine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cannabidiol
Mercaptopurine {u} may lead to a major life threatening interaction when taken with {v} Certolizumab pegol
Mercaptopurine {u} may lead to a major life threatening interaction when taken with {v} Natalizumab
Mercaptopurine (Compound) resembles Adenine (Compound)
Mercaptopurine (Compound) treats Crohn's disease (Disease)
Mercaptopurine (Compound) binds AOX1 (Gene)
Mercaptopurine (Compound) causes Candida infection (Side Effect)
Mercaptopurine may cause a minor interaction that can limit clinical effects when taken with Trovafloxacin
Mercaptopurine may cause a minor interaction that can limit clinical effects when taken with Sparfloxacin
Mercaptopurine may cause a moderate interaction that could exacerbate diseases when taken with Warfarin
Mercaptopurine may cause a moderate interaction that could exacerbate diseases when taken with Cannabidiol
Mercaptopurine may lead to a major life threatening interaction when taken with Certolizumab pegol
Mercaptopurine may lead to a major life threatening interaction when taken with Natalizumab