DDInter1340 DDInter387
Originally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class, and its approval was followed by the formulation of many other proton pump inhibitor drugs. Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults [FDA label].
Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.
Omeprazole {u} (Compound) palliates {v} (Disease) esophageal cancer
esophageal cancer {u} (Disease) is treated by {v} (Compound) Cisplatin
Omeprazole {u} (Compound) binds {v} (Gene) ABCC3
ABCC3 {u} (Gene) is bound by {v} (Compound) Cisplatin
Omeprazole {u} (Compound) causes {v} (Side Effect) Anaphylactic shock
Anaphylactic shock {u} (Side Effect) is caused by {v} (Compound) Cisplatin
Omeprazole {u} (Compound) resembles {v} (Compound) Lansoprazole
Lansoprazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cisplatin
Omeprazole {u} (Compound) resembles {v} (Compound) Pantoprazole
Pantoprazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cisplatin
Omeprazole {u} (Compound) resembles {v} (Compound) Rabeprazole
Rabeprazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cisplatin
Omeprazole {u} (Compound) palliates {v} (Disease) esophageal cancer
esophageal cancer {u} (Disease) resembles {v} (Disease) lung cancer
lung cancer {u} (Disease) is treated by {v} (Compound) Cisplatin
Omeprazole {u} (Compound) binds {v} (Gene) ABCC3
ABCC3 {u} (Gene) is associated with {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is treated by {v} (Compound) Cisplatin
Omeprazole {u} (Compound) binds {v} (Gene) CYP2C9
CYP2C9 {u} (Gene) is bound by {v} (Compound) Methoxyflurane
Methoxyflurane {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cisplatin
Omeprazole {u} (Compound) causes {v} (Side Effect) Anaphylactic shock
Anaphylactic shock {u} (Side Effect) is caused by {v} (Compound) Norfloxacin
Norfloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cisplatin
Omeprazole (Compound) palliates esophageal cancer (Disease) and esophageal cancer (Disease) is treated by Cisplatin (Compound)
Omeprazole (Compound) binds ABCC3 (Gene) and ABCC3 (Gene) is bound by Cisplatin (Compound)
Omeprazole (Compound) causes Anaphylactic shock (Side Effect) and Anaphylactic shock (Side Effect) is caused by Cisplatin (Compound)
Omeprazole (Compound) resembles Lansoprazole (Compound) and Lansoprazole may cause a moderate interaction that could exacerbate diseases when taken with Cisplatin
Omeprazole (Compound) resembles Pantoprazole (Compound) and Pantoprazole may cause a moderate interaction that could exacerbate diseases when taken with Cisplatin
Omeprazole (Compound) resembles Rabeprazole (Compound) and Rabeprazole may cause a moderate interaction that could exacerbate diseases when taken with Cisplatin
Omeprazole (Compound) palliates esophageal cancer (Disease) and esophageal cancer (Disease) resembles lung cancer (Disease) and lung cancer (Disease) is treated by Cisplatin (Compound)
Omeprazole (Compound) binds ABCC3 (Gene) and ABCC3 (Gene) is associated with hematologic cancer (Disease) and hematologic cancer (Disease) is treated by Cisplatin (Compound)
Omeprazole (Compound) binds CYP2C9 (Gene) and CYP2C9 (Gene) is bound by Methoxyflurane (Compound) and Methoxyflurane may cause a moderate interaction that could exacerbate diseases when taken with Cisplatin
Omeprazole (Compound) causes Anaphylactic shock (Side Effect) and Anaphylactic shock (Side Effect) is caused by Norfloxacin (Compound) and Norfloxacin may cause a minor interaction that can limit clinical effects when taken with Cisplatin