DDInter699 DDInter105
Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Etodolac {u} (Compound) binds {v} (Gene) CYP2C9
Etodolac {u} (Compound) upregulates {v} (Gene) SERPINA3
Etodolac {u} (Compound) palliates {v} (Disease) osteoarthritis
Etodolac {u} (Compound) is included by {v} (Pharmacologic Class) Nonsteroidal Anti-inflammatory Compounds
Etodolac {u} (Compound) downregulates {v} (Gene) RAI14
Etodolac {u} (Compound) causes {v} (Side Effect) Rhinitis
Etodolac {u} may cause a minor interaction that can limit clinical effects when taken with {v} Linaclotide
Etodolac {u} may cause a minor interaction that can limit clinical effects when taken with {v} Nizatidine
Etodolac {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Anistreplase
Etodolac {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sodium sulfate
Etodolac (Compound) binds CYP2C9 (Gene)
Etodolac (Compound) upregulates SERPINA3 (Gene)
Etodolac (Compound) palliates osteoarthritis (Disease)
Etodolac (Compound) is included by Nonsteroidal Anti-inflammatory Compounds (Pharmacologic Class)
Etodolac (Compound) downregulates RAI14 (Gene)
Etodolac (Compound) causes Rhinitis (Side Effect)
Etodolac may cause a minor interaction that can limit clinical effects when taken with Linaclotide
Etodolac may cause a minor interaction that can limit clinical effects when taken with Nizatidine
Etodolac may cause a moderate interaction that could exacerbate diseases when taken with Anistreplase
Etodolac may cause a moderate interaction that could exacerbate diseases when taken with Sodium sulfate