DDInter263 DDInter1620
Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to [Theophylline] and [Theobromine].[A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in various teas and cacao beans, which are different than coffee beans. Caffeine is also used in a variety of cosmetic products and can be administered topically, orally, by inhalation, or by injection. The caffeine citrate injection, used for apnea of the premature newborn, was initially approved by the FDA in 1999. According to an article from 2017, more than 15 million babies are born prematurely worldwide. This correlates to about 1 in 10 births. Premature birth can lead to apnea and bronchopulmonary dysplasia, a
Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.
Caffeine {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Ropivacaine
Caffeine {u} (Compound) causes {v} (Side Effect) Cardiac disorder
Cardiac disorder {u} (Side Effect) is caused by {v} (Compound) Ropivacaine
Caffeine {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Lidocaine
Lidocaine {u} (Compound) resembles {v} (Compound) Ropivacaine
Caffeine {u} (Compound) causes {v} (Side Effect) Cardiac disorder
Cardiac disorder {u} (Side Effect) is caused by {v} (Compound) Lidocaine
Lidocaine {u} (Compound) resembles {v} (Compound) Ropivacaine
Caffeine {u} (Compound) resembles {v} (Compound) Oxtriphylline
Oxtriphylline {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Ropivacaine
Caffeine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Bupivacaine
Bupivacaine {u} (Compound) resembles {v} (Compound) Ropivacaine
Caffeine {u} (Compound) causes {v} (Side Effect) Skin disorder
Skin disorder {u} (Side Effect) is caused by {v} (Compound) Bupivacaine
Bupivacaine {u} (Compound) resembles {v} (Compound) Ropivacaine
Caffeine {u} (Compound) resembles {v} (Compound) Oxtriphylline
Oxtriphylline {u} (Compound) causes {v} (Side Effect) Injection site reaction
Injection site reaction {u} (Side Effect) is caused by {v} (Compound) Ropivacaine
Caffeine {u} (Compound) resembles {v} (Compound) Dyphylline
Dyphylline {u} (Compound) causes {v} (Side Effect) Tachycardia
Tachycardia {u} (Side Effect) is caused by {v} (Compound) Ropivacaine
Caffeine {u} (Compound) resembles {v} (Compound) Pentoxifylline
Pentoxifylline {u} (Compound) downregulates {v} (Gene) PTK2
PTK2 {u} (Gene) is downregulated by {v} (Compound) Ropivacaine
Caffeine (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Ropivacaine (Compound)
Caffeine (Compound) causes Cardiac disorder (Side Effect) and Cardiac disorder (Side Effect) is caused by Ropivacaine (Compound)
Caffeine (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Lidocaine (Compound) and Lidocaine (Compound) resembles Ropivacaine (Compound)
Caffeine (Compound) causes Cardiac disorder (Side Effect) and Cardiac disorder (Side Effect) is caused by Lidocaine (Compound) and Lidocaine (Compound) resembles Ropivacaine (Compound)
Caffeine (Compound) resembles Oxtriphylline (Compound) and Oxtriphylline (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Ropivacaine (Compound)
Caffeine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Bupivacaine (Compound) and Bupivacaine (Compound) resembles Ropivacaine (Compound)
Caffeine (Compound) causes Skin disorder (Side Effect) and Skin disorder (Side Effect) is caused by Bupivacaine (Compound) and Bupivacaine (Compound) resembles Ropivacaine (Compound)
Caffeine (Compound) resembles Oxtriphylline (Compound) and Oxtriphylline (Compound) causes Injection site reaction (Side Effect) and Injection site reaction (Side Effect) is caused by Ropivacaine (Compound)
Caffeine (Compound) resembles Dyphylline (Compound) and Dyphylline (Compound) causes Tachycardia (Side Effect) and Tachycardia (Side Effect) is caused by Ropivacaine (Compound)
Caffeine (Compound) resembles Pentoxifylline (Compound) and Pentoxifylline (Compound) downregulates PTK2 (Gene) and PTK2 (Gene) is downregulated by Ropivacaine (Compound)