DDInter641 DDInter1344
Enflurane is a halogenated inhalational anesthetic initially approved by the FDA in 1972. Since this date, it has been withdrawn from the US market.[L13646,L13649] Unlike its other inhalational anesthetic counterparts including [isoflurane] and [halothane], enflurane is known to induce seizure activity. In addition, it is known to cause increased cardio depressant effects when compared to other inhaled anesthetics.
Opium is the first substance of the diverse group of the opiates. It has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years by the Sumerians. During the years, opium was used as a sedative and hypnotic, but it was determined to be addictive. Opium is extracted from _Papaver somniferum_, which is more known as poppies. This plant is an integrant of the Papaveraceae family, and it is characterized by solitary leaves and capsulated fruits. Therefore, opium is a sticky brown resin obtained by collecting and drying the latex that exudes from the poppy pods. Once extracted, opium contains two main groups of alkaloids; the psychoactive constituents which are in the category of phenanthrenes and alkaloids that have no central nervous system effect in the category of isoquinolines. Morphine is the most prevalent and principal alkaloid in opium, and it is responsible for most of the harmful effects of opium. Opium has gradually been superseded by a variety of synthetic opioids and general anesthetics. Some of the isolated derivatives of opium are morphine, noscapine, strychnine, veratrine, colchicine, codeine, and quinine. Opium is a prohibited drug of abuse in most countries, but the illegal production of this drug and its derivatives keeps being registered. There is some legal production of opium in different countries for the obtention of alkaloids by extraction.
Enflurane {u} (Compound) resembles {v} (Compound) Isoflurane
Isoflurane {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Enflurane {u} (Compound) resembles {v} (Compound) Desflurane
Desflurane {u} (Compound) resembles {v} (Compound) Isoflurane
Isoflurane {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Enflurane {u} (Compound) resembles {v} (Compound) Isoflurane
Isoflurane {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Doxepin
Doxepin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Enflurane {u} (Compound) binds {v} (Gene) KCNN4
KCNN4 {u} (Gene) is bound by {v} (Compound) Halothane
Halothane {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Enflurane {u} (Compound) resembles {v} (Compound) Isoflurane
Isoflurane {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Morphine
Morphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Enflurane {u} (Compound) is included by {v} (Pharmacologic Class) General Anesthesia
General Anesthesia {u} (Pharmacologic Class) includes {v} (Compound) Isoflurane
Isoflurane {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Enflurane {u} (Compound) causes {v} (Side Effect) Hyperkalaemia
Hyperkalaemia {u} (Side Effect) is caused by {v} (Compound) Solifenacin
Solifenacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Enflurane {u} (Compound) causes {v} (Side Effect) Hypotension
Hypotension {u} (Side Effect) is caused by {v} (Compound) Selegiline
Selegiline {u} may lead to a major life threatening interaction when taken with {v} Opium
Enflurane {u} (Compound) binds {v} (Gene) CYP2E1
CYP2E1 {u} (Gene) is bound by {v} (Compound) Phenelzine
Phenelzine {u} may lead to a major life threatening interaction when taken with {v} Opium
Enflurane (Compound) resembles Isoflurane (Compound) and Isoflurane may cause a moderate interaction that could exacerbate diseases when taken with Opium
Enflurane (Compound) resembles Desflurane (Compound) and Desflurane (Compound) resembles Isoflurane (Compound) and Isoflurane may cause a moderate interaction that could exacerbate diseases when taken with Opium
Enflurane (Compound) resembles Isoflurane (Compound) and Isoflurane may cause a moderate interaction that could exacerbate diseases when taken with Doxepin and Doxepin may cause a moderate interaction that could exacerbate diseases when taken with Opium
Enflurane (Compound) binds KCNN4 (Gene) and KCNN4 (Gene) is bound by Halothane (Compound) and Halothane may cause a moderate interaction that could exacerbate diseases when taken with Opium
Enflurane (Compound) resembles Isoflurane (Compound) and Isoflurane may cause a moderate interaction that could exacerbate diseases when taken with Morphine and Morphine may cause a moderate interaction that could exacerbate diseases when taken with Opium
Enflurane (Compound) is included by General Anesthesia (Pharmacologic Class) and General Anesthesia (Pharmacologic Class) includes Isoflurane (Compound) and Isoflurane may cause a moderate interaction that could exacerbate diseases when taken with Opium
Enflurane (Compound) causes Hyperkalaemia (Side Effect) and Hyperkalaemia (Side Effect) is caused by Solifenacin (Compound) and Solifenacin may cause a moderate interaction that could exacerbate diseases when taken with Opium
Enflurane (Compound) causes Hypotension (Side Effect) and Hypotension (Side Effect) is caused by Selegiline (Compound) and Selegiline may lead to a major life threatening interaction when taken with Opium
Enflurane (Compound) binds CYP2E1 (Gene) and CYP2E1 (Gene) is bound by Phenelzine (Compound) and Phenelzine may lead to a major life threatening interaction when taken with Opium