DDInter298 DDInter813
Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma. Early clinical studies of carboplatin were performed in 1982. Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.
Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. It is available in oral formulations. Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are essential for bacterial growth.
Carboplatin {u} (Compound) causes {v} (Side Effect) Pain
Pain {u} (Side Effect) is caused by {v} (Compound) Gemifloxacin
Carboplatin {u} (Compound) causes {v} (Side Effect) Pain
Pain {u} (Side Effect) is caused by {v} (Compound) Levofloxacin
Levofloxacin {u} (Compound) resembles {v} (Compound) Gemifloxacin
Carboplatin {u} (Compound) treats {v} (Disease) esophageal cancer
esophageal cancer {u} (Disease) is treated by {v} (Compound) Cisplatin
Cisplatin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Gemifloxacin
Carboplatin {u} (Compound) causes {v} (Side Effect) Pain
Pain {u} (Side Effect) is caused by {v} (Compound) Trovafloxacin
Trovafloxacin {u} (Compound) resembles {v} (Compound) Gemifloxacin
Carboplatin {u} (Compound) treats {v} (Disease) ovarian cancer
ovarian cancer {u} (Disease) is treated by {v} (Compound) Epirubicin
Epirubicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Gemifloxacin
Carboplatin {u} (Compound) treats {v} (Disease) ovarian cancer
ovarian cancer {u} (Disease) is treated by {v} (Compound) Paclitaxel
Paclitaxel {u} may cause a minor interaction that can limit clinical effects when taken with {v} Gemifloxacin
Carboplatin {u} (Compound) causes {v} (Side Effect) Pain
Pain {u} (Side Effect) is caused by {v} (Compound) Topotecan
Topotecan {u} may cause a minor interaction that can limit clinical effects when taken with {v} Gemifloxacin
Carboplatin {u} (Compound) binds {v} (Gene) GSTM1
GSTM1 {u} (Gene) is bound by {v} (Compound) Cisplatin
Cisplatin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Gemifloxacin
Carboplatin {u} (Compound) binds {v} (Gene) MPO
MPO {u} (Gene) is bound by {v} (Compound) Oxaliplatin
Oxaliplatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Gemifloxacin
Carboplatin {u} (Compound) causes {v} (Side Effect) Pain
Pain {u} (Side Effect) is caused by {v} (Compound) Procarbazine
Procarbazine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Gemifloxacin
Carboplatin (Compound) causes Pain (Side Effect) and Pain (Side Effect) is caused by Gemifloxacin (Compound)
Carboplatin (Compound) causes Pain (Side Effect) and Pain (Side Effect) is caused by Levofloxacin (Compound) and Levofloxacin (Compound) resembles Gemifloxacin (Compound)
Carboplatin (Compound) treats esophageal cancer (Disease) and esophageal cancer (Disease) is treated by Cisplatin (Compound) and Cisplatin may cause a minor interaction that can limit clinical effects when taken with Gemifloxacin
Carboplatin (Compound) causes Pain (Side Effect) and Pain (Side Effect) is caused by Trovafloxacin (Compound) and Trovafloxacin (Compound) resembles Gemifloxacin (Compound)
Carboplatin (Compound) treats ovarian cancer (Disease) and ovarian cancer (Disease) is treated by Epirubicin (Compound) and Epirubicin may cause a moderate interaction that could exacerbate diseases when taken with Gemifloxacin
Carboplatin (Compound) treats ovarian cancer (Disease) and ovarian cancer (Disease) is treated by Paclitaxel (Compound) and Paclitaxel may cause a minor interaction that can limit clinical effects when taken with Gemifloxacin
Carboplatin (Compound) causes Pain (Side Effect) and Pain (Side Effect) is caused by Topotecan (Compound) and Topotecan may cause a minor interaction that can limit clinical effects when taken with Gemifloxacin
Carboplatin (Compound) binds GSTM1 (Gene) and GSTM1 (Gene) is bound by Cisplatin (Compound) and Cisplatin may cause a minor interaction that can limit clinical effects when taken with Gemifloxacin
Carboplatin (Compound) binds MPO (Gene) and MPO (Gene) is bound by Oxaliplatin (Compound) and Oxaliplatin may cause a moderate interaction that could exacerbate diseases when taken with Gemifloxacin
Carboplatin (Compound) causes Pain (Side Effect) and Pain (Side Effect) is caused by Procarbazine (Compound) and Procarbazine may cause a minor interaction that can limit clinical effects when taken with Gemifloxacin