DDInter320 DDInter856
A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated heparin is more specific than LMWH for thrombin. Furthermore, the effects of UH can typically be reversed by using protamine sulfate.
Cefmetazole {u} (Compound) resembles {v} (Compound) Cefmenoxime
Cefmetazole {u} (Compound) resembles {v} (Compound) Latamoxef
Cefmetazole {u} (Compound) binds {v} (Gene) SLC15A1
Cefmetazole {u} (Compound) downregulates {v} (Gene) HMG20B
Cefmetazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Neomycin
Cefmetazole (Compound) resembles Cefmenoxime (Compound)
Cefmetazole (Compound) resembles Latamoxef (Compound)
Cefmetazole (Compound) binds SLC15A1 (Gene)
Cefmetazole (Compound) downregulates HMG20B (Gene)
Cefmetazole may cause a moderate interaction that could exacerbate diseases when taken with Neomycin