DDInter1867 DDInter1635
A phenothiazine used as an antipsychotic agent and as an antiemetic.
Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.[L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 adrenergic receptor agonist, [salbutamol]. Salmeterol was first described in the literature in 1988. Salmeterol's structure is similar to salbutamol's with an aralkyloxy-alkyl substitution on the amine. Salmeterol was granted FDA approval on 4 February 1994.
Triflupromazine {u} (Compound) upregulates {v} (Gene) HMGCS1
HMGCS1 {u} (Gene) is upregulated by {v} (Compound) Salmeterol
Triflupromazine {u} (Compound) downregulates {v} (Gene) CDC20
CDC20 {u} (Gene) is downregulated by {v} (Compound) Salmeterol
Triflupromazine {u} (Compound) resembles {v} (Compound) Clomipramine
Clomipramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Salmeterol
Triflupromazine {u} (Compound) resembles {v} (Compound) Promazine
Promazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Salmeterol
Triflupromazine {u} (Compound) upregulates {v} (Gene) HMGCS1
HMGCS1 {u} (Gene) is regulated by {v} (Gene) EDEM1
EDEM1 {u} (Gene) is upregulated by {v} (Compound) Salmeterol
Triflupromazine {u} (Compound) upregulates {v} (Gene) INSIG1
INSIG1 {u} (Gene) regulates {v} (Gene) ADRB2
ADRB2 {u} (Gene) is bound by {v} (Compound) Salmeterol
Triflupromazine {u} (Compound) upregulates {v} (Gene) FDPS
FDPS {u} (Gene) regulates {v} (Gene) CDC20
CDC20 {u} (Gene) is downregulated by {v} (Compound) Salmeterol
Triflupromazine {u} (Compound) upregulates {v} (Gene) FDFT1
FDFT1 {u} (Gene) regulates {v} (Gene) HMGCR
HMGCR {u} (Gene) is upregulated by {v} (Compound) Salmeterol
Triflupromazine {u} (Compound) upregulates {v} (Gene) HMGCR
HMGCR {u} (Gene) interacts with {v} (Gene) and {u} (Gene) regulates {v} (Gene) INSIG1
INSIG1 {u} (Gene) is upregulated by {v} (Compound) Salmeterol
Triflupromazine {u} (Compound) downregulates {v} (Gene) CDC20
CDC20 {u} (Gene) is regulated by {v} (Gene) CYP3A5
CYP3A5 {u} (Gene) is bound by {v} (Compound) Salmeterol
Triflupromazine (Compound) upregulates HMGCS1 (Gene) and HMGCS1 (Gene) is upregulated by Salmeterol (Compound)
Triflupromazine (Compound) downregulates CDC20 (Gene) and CDC20 (Gene) is downregulated by Salmeterol (Compound)
Triflupromazine (Compound) resembles Clomipramine (Compound) and Clomipramine may cause a moderate interaction that could exacerbate diseases when taken with Salmeterol
Triflupromazine (Compound) resembles Promazine (Compound) and Promazine may cause a moderate interaction that could exacerbate diseases when taken with Salmeterol
Triflupromazine (Compound) upregulates HMGCS1 (Gene) and HMGCS1 (Gene) is regulated by EDEM1 (Gene) and EDEM1 (Gene) is upregulated by Salmeterol (Compound)
Triflupromazine (Compound) upregulates INSIG1 (Gene) and INSIG1 (Gene) regulates ADRB2 (Gene) and ADRB2 (Gene) is bound by Salmeterol (Compound)
Triflupromazine (Compound) upregulates FDPS (Gene) and FDPS (Gene) regulates CDC20 (Gene) and CDC20 (Gene) is downregulated by Salmeterol (Compound)
Triflupromazine (Compound) upregulates FDFT1 (Gene) and FDFT1 (Gene) regulates HMGCR (Gene) and HMGCR (Gene) is upregulated by Salmeterol (Compound)
Triflupromazine (Compound) upregulates HMGCR (Gene) and HMGCR (Gene) interacts with INSIG1 (Gene) and HMGCR (Gene) regulates INSIG1 (Gene) and INSIG1 (Gene) is upregulated by Salmeterol (Compound)
Triflupromazine (Compound) downregulates CDC20 (Gene) and CDC20 (Gene) is regulated by CYP3A5 (Gene) and CYP3A5 (Gene) is bound by Salmeterol (Compound)