DDInter383 DDInter255
Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.
Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought about. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.
Cinoxacin {u} (Compound) causes {v} (Side Effect) Erythema multiforme
Erythema multiforme {u} (Side Effect) is caused by {v} (Compound) Busulfan
Cinoxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Idarubicin
Idarubicin {u} (Compound) treats {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is treated by {v} (Compound) Busulfan
Cinoxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Epirubicin
Epirubicin {u} (Compound) treats {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is treated by {v} (Compound) Busulfan
Cinoxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Idarubicin
Idarubicin {u} (Compound) upregulates {v} (Gene) MCOLN1
MCOLN1 {u} (Gene) is upregulated by {v} (Compound) Busulfan
Cinoxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Epirubicin
Epirubicin {u} (Compound) upregulates {v} (Gene) MCOLN1
MCOLN1 {u} (Gene) is upregulated by {v} (Compound) Busulfan
Cinoxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Bleomycin
Bleomycin {u} (Compound) causes {v} (Side Effect) Cystitis haemorrhagic
Cystitis haemorrhagic {u} (Side Effect) is caused by {v} (Compound) Busulfan
Cinoxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Procarbazine
Procarbazine {u} (Compound) is included by {v} (Pharmacologic Class) Alkylating Activity
Alkylating Activity {u} (Pharmacologic Class) includes {v} (Compound) Busulfan
Cinoxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ifosfamide
Ifosfamide {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Busulfan
Cinoxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Procarbazine
Procarbazine {u} (Compound) downregulates {v} (Gene) TIMM9
TIMM9 {u} (Gene) is downregulated by {v} (Compound) Busulfan
Cinoxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ifosfamide
Ifosfamide {u} (Compound) upregulates {v} (Gene) NNT
NNT {u} (Gene) is downregulated by {v} (Compound) Busulfan
Cinoxacin (Compound) causes Erythema multiforme (Side Effect) and Erythema multiforme (Side Effect) is caused by Busulfan (Compound)
Cinoxacin may cause a minor interaction that can limit clinical effects when taken with Idarubicin and Idarubicin (Compound) treats hematologic cancer (Disease) and hematologic cancer (Disease) is treated by Busulfan (Compound)
Cinoxacin may cause a minor interaction that can limit clinical effects when taken with Epirubicin and Epirubicin (Compound) treats hematologic cancer (Disease) and hematologic cancer (Disease) is treated by Busulfan (Compound)
Cinoxacin may cause a minor interaction that can limit clinical effects when taken with Idarubicin and Idarubicin (Compound) upregulates MCOLN1 (Gene) and MCOLN1 (Gene) is upregulated by Busulfan (Compound)
Cinoxacin may cause a minor interaction that can limit clinical effects when taken with Epirubicin and Epirubicin (Compound) upregulates MCOLN1 (Gene) and MCOLN1 (Gene) is upregulated by Busulfan (Compound)
Cinoxacin may cause a minor interaction that can limit clinical effects when taken with Bleomycin and Bleomycin (Compound) causes Cystitis haemorrhagic (Side Effect) and Cystitis haemorrhagic (Side Effect) is caused by Busulfan (Compound)
Cinoxacin may cause a minor interaction that can limit clinical effects when taken with Procarbazine and Procarbazine (Compound) is included by Alkylating Activity (Pharmacologic Class) and Alkylating Activity (Pharmacologic Class) includes Busulfan (Compound)
Cinoxacin may cause a minor interaction that can limit clinical effects when taken with Ifosfamide and Ifosfamide (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Busulfan (Compound)
Cinoxacin may cause a minor interaction that can limit clinical effects when taken with Procarbazine and Procarbazine (Compound) downregulates TIMM9 (Gene) and TIMM9 (Gene) is downregulated by Busulfan (Compound)
Cinoxacin may cause a minor interaction that can limit clinical effects when taken with Ifosfamide and Ifosfamide (Compound) upregulates NNT (Gene) and NNT (Gene) is downregulated by Busulfan (Compound)