DDInter93 DDInter1340
Anagrelide is a platelet-reducing agent used to lower dangerously elevated platelet levels (i.e. to treat thrombocythemia) in patients with myeloproliferative neoplasms. It is an oral imidazoquinazoline that was first approved for use in the US in 1997. It appears to carry a better response rate than other thrombocythemia treatments (e.g. [busulfan], [hydroxyurea]) and may be better tolerated.
Originally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class, and its approval was followed by the formulation of many other proton pump inhibitor drugs . Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults [FDA label].
Anagrelide {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Omeprazole
Anagrelide {u} (Compound) upregulates {v} (Gene) TIPARP
TIPARP {u} (Gene) is upregulated by {v} (Compound) Omeprazole
Anagrelide {u} (Compound) causes {v} (Side Effect) Urethral disorder
Urethral disorder {u} (Side Effect) is caused by {v} (Compound) Omeprazole
Anagrelide {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Pantoprazole
Pantoprazole {u} (Compound) resembles {v} (Compound) Omeprazole
Anagrelide {u} (Compound) upregulates {v} (Gene) TIPARP
TIPARP {u} (Gene) is upregulated by {v} (Compound) Esomeprazole
Esomeprazole {u} (Compound) resembles {v} (Compound) Omeprazole
Anagrelide {u} (Compound) causes {v} (Side Effect) Urethral disorder
Urethral disorder {u} (Side Effect) is caused by {v} (Compound) Pantoprazole
Pantoprazole {u} (Compound) resembles {v} (Compound) Omeprazole
Anagrelide {u} (Compound) causes {v} (Side Effect) Accidental injury
Accidental injury {u} (Side Effect) is caused by {v} (Compound) Esomeprazole
Esomeprazole {u} (Compound) resembles {v} (Compound) Omeprazole
Anagrelide {u} (Compound) downregulates {v} (Gene) ACAT2
ACAT2 {u} (Gene) is downregulated by {v} (Compound) Pantoprazole
Pantoprazole {u} (Compound) resembles {v} (Compound) Omeprazole
Anagrelide {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Rabeprazole
Rabeprazole {u} (Compound) resembles {v} (Compound) Omeprazole
Anagrelide {u} (Compound) upregulates {v} (Gene) TIPARP
TIPARP {u} (Gene) is regulated by {v} (Gene) CYP1A1
CYP1A1 {u} (Gene) is bound by {v} (Compound) Omeprazole
Anagrelide (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Omeprazole (Compound)
Anagrelide (Compound) upregulates TIPARP (Gene) and TIPARP (Gene) is upregulated by Omeprazole (Compound)
Anagrelide (Compound) causes Urethral disorder (Side Effect) and Urethral disorder (Side Effect) is caused by Omeprazole (Compound)
Anagrelide (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Pantoprazole (Compound) and Pantoprazole (Compound) resembles Omeprazole (Compound)
Anagrelide (Compound) upregulates TIPARP (Gene) and TIPARP (Gene) is upregulated by Esomeprazole (Compound) and Esomeprazole (Compound) resembles Omeprazole (Compound)
Anagrelide (Compound) causes Urethral disorder (Side Effect) and Urethral disorder (Side Effect) is caused by Pantoprazole (Compound) and Pantoprazole (Compound) resembles Omeprazole (Compound)
Anagrelide (Compound) causes Accidental injury (Side Effect) and Accidental injury (Side Effect) is caused by Esomeprazole (Compound) and Esomeprazole (Compound) resembles Omeprazole (Compound)
Anagrelide (Compound) downregulates ACAT2 (Gene) and ACAT2 (Gene) is downregulated by Pantoprazole (Compound) and Pantoprazole (Compound) resembles Omeprazole (Compound)
Anagrelide (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Rabeprazole (Compound) and Rabeprazole (Compound) resembles Omeprazole (Compound)
Anagrelide (Compound) upregulates TIPARP (Gene) and TIPARP (Gene) is regulated by CYP1A1 (Gene) and CYP1A1 (Gene) is bound by Omeprazole (Compound)