DDInter1141 DDInter624
17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1. For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with zidovudine or tenofovir is the preferred NNRTI-based regimen. Efavirenz is also used in combination with other antiretroviral agents as part of an expanded postexposure prophylaxis regimen to prevent HIV transmission for those exposed to materials associated with a high risk for HIV transmission.
Megestrol acetate {u} (Compound) resembles {v} (Compound) Difluprednate
Difluprednate {u} (Compound) causes {v} (Side Effect) Headache
Headache {u} (Side Effect) is caused by {v} (Compound) Efavirenz
Megestrol acetate {u} (Compound) resembles {v} (Compound) Ethynodiol
Ethynodiol {u} (Compound) downregulates {v} (Gene) CCDC86
CCDC86 {u} (Gene) is downregulated by {v} (Compound) Efavirenz
Megestrol acetate {u} (Compound) resembles {v} (Compound) Methyltestosterone
Methyltestosterone {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Efavirenz
Megestrol acetate {u} (Compound) resembles {v} (Compound) Methyltestosterone
Methyltestosterone {u} (Compound) downregulates {v} (Gene) RFC2
RFC2 {u} (Gene) is downregulated by {v} (Compound) Efavirenz
Megestrol acetate {u} (Compound) resembles {v} (Compound) Methyltestosterone
Methyltestosterone {u} (Compound) causes {v} (Side Effect) Blood cholesterol increased
Blood cholesterol increased {u} (Side Effect) is caused by {v} (Compound) Efavirenz
Megestrol acetate {u} (Compound) resembles {v} (Compound) Cortisone acetate
Cortisone acetate {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Efavirenz
Megestrol acetate {u} (Compound) resembles {v} (Compound) Prednicarbate
Prednicarbate {u} (Compound) upregulates {v} (Gene) IKBKB
IKBKB {u} (Gene) is upregulated by {v} (Compound) Efavirenz
Megestrol acetate {u} (Compound) binds {v} (Gene) NR3C1
NR3C1 {u} (Gene) regulates {v} (Gene) PFN1
PFN1 {u} (Gene) is downregulated by {v} (Compound) Efavirenz
Megestrol acetate {u} (Compound) binds {v} (Gene) NR3C1
NR3C1 {u} (Gene) regulates {v} (Gene) TBX2
TBX2 {u} (Gene) is upregulated by {v} (Compound) Efavirenz
Megestrol acetate {u} (Compound) palliates {v} (Disease) breast cancer
breast cancer {u} (Disease) is associated with {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Efavirenz
Megestrol acetate (Compound) resembles Difluprednate (Compound) and Difluprednate (Compound) causes Headache (Side Effect) and Headache (Side Effect) is caused by Efavirenz (Compound)
Megestrol acetate (Compound) resembles Ethynodiol (Compound) and Ethynodiol (Compound) downregulates CCDC86 (Gene) and CCDC86 (Gene) is downregulated by Efavirenz (Compound)
Megestrol acetate (Compound) resembles Methyltestosterone (Compound) and Methyltestosterone (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Efavirenz (Compound)
Megestrol acetate (Compound) resembles Methyltestosterone (Compound) and Methyltestosterone (Compound) downregulates RFC2 (Gene) and RFC2 (Gene) is downregulated by Efavirenz (Compound)
Megestrol acetate (Compound) resembles Methyltestosterone (Compound) and Methyltestosterone (Compound) causes Blood cholesterol increased (Side Effect) and Blood cholesterol increased (Side Effect) is caused by Efavirenz (Compound)
Megestrol acetate (Compound) resembles Cortisone acetate (Compound) and Cortisone acetate (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Efavirenz (Compound)
Megestrol acetate (Compound) resembles Prednicarbate (Compound) and Prednicarbate (Compound) upregulates IKBKB (Gene) and IKBKB (Gene) is upregulated by Efavirenz (Compound)
Megestrol acetate (Compound) binds NR3C1 (Gene) and NR3C1 (Gene) regulates PFN1 (Gene) and PFN1 (Gene) is downregulated by Efavirenz (Compound)
Megestrol acetate (Compound) binds NR3C1 (Gene) and NR3C1 (Gene) regulates TBX2 (Gene) and TBX2 (Gene) is upregulated by Efavirenz (Compound)
Megestrol acetate (Compound) palliates breast cancer (Disease) and breast cancer (Disease) is associated with CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Efavirenz (Compound)