DDInter35 DDInter178
A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Bendamustine is a nitrogen mustard drug indicated for use in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed during or within six months of treatment with rituximab or a rituximab-containing regimen. Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases resulting in cell death. It is active against both active and quiescent cells, although the exact mechanism of action is unknown.
Albendazole {u} (Compound) resembles {v} (Compound) Mebendazole
Albendazole {u} (Compound) binds {v} (Gene) ABCB1
Albendazole {u} (Compound) upregulates {v} (Gene) KIF14
Albendazole {u} (Compound) is included by {v} (Pharmacologic Class) Cytochrome P450 1A Inducers
Albendazole {u} (Compound) downregulates {v} (Gene) GNPDA1
Albendazole {u} (Compound) causes {v} (Side Effect) Acute hepatic failure
Albendazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cimetidine
Albendazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Dexamethasone
Albendazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Carbamazepine
Albendazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nevirapine
Albendazole (Compound) resembles Mebendazole (Compound)
Albendazole (Compound) binds ABCB1 (Gene)
Albendazole (Compound) upregulates KIF14 (Gene)
Albendazole (Compound) is included by Cytochrome P450 1A Inducers (Pharmacologic Class)
Albendazole (Compound) downregulates GNPDA1 (Gene)
Albendazole (Compound) causes Acute hepatic failure (Side Effect)
Albendazole may cause a minor interaction that can limit clinical effects when taken with Cimetidine
Albendazole may cause a minor interaction that can limit clinical effects when taken with Dexamethasone
Albendazole may cause a moderate interaction that could exacerbate diseases when taken with Carbamazepine
Albendazole may cause a moderate interaction that could exacerbate diseases when taken with Nevirapine