DDInter682 DDInter1082
Estrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. It is produced in vivo from androstenedione or from testosterone via estradiol. It is produced primarily in the ovaries, placenta, and in peripheral tissues (especially adipose tissue) through conversion of adrostenedione. Estrone may be further metabolized to 16-alpha-hydroxyestrone, which may be reduced to estriol by estradiol dehydrogenase.
Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM). It is sold by Sanofi-Aventis under the brand name Adlyxin in the US and Lyxumia in the EU. Adlyxin recieved FDA approval July 28, 2016.
Estrone {u} (Compound) resembles {v} (Compound) Estramustine
Estrone {u} (Compound) resembles {v} (Compound) Levorphanol
Estrone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Exemestane
Estrone {u} (Compound) treats {v} (Disease) prostate cancer
Estrone {u} (Compound) binds {v} (Gene) CYP1A2
Estrone {u} (Compound) upregulates {v} (Gene) CDK6
Estrone {u} (Compound) palliates {v} (Disease) breast cancer
Estrone {u} (Compound) downregulates {v} (Gene) RNH1
Estrone {u} (Compound) causes {v} (Side Effect) Dermatitis hemorrhagic
Estrone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cimetidine
Estrone (Compound) resembles Estramustine (Compound)
Estrone (Compound) resembles Levorphanol (Compound)
Estrone may cause a moderate interaction that could exacerbate diseases when taken with Exemestane
Estrone (Compound) treats prostate cancer (Disease)
Estrone (Compound) binds CYP1A2 (Gene)
Estrone (Compound) upregulates CDK6 (Gene)
Estrone (Compound) palliates breast cancer (Disease)
Estrone (Compound) downregulates RNH1 (Gene)
Estrone (Compound) causes Dermatitis hemorrhagic (Side Effect)
Estrone may cause a minor interaction that can limit clinical effects when taken with Cimetidine