DDInter1340 DDInter1304
Originally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class, and its approval was followed by the formulation of many other proton pump inhibitor drugs. Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults [FDA label].
Nitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced relief from chest pain.[A180166,A180172] Its use as a treatment for angina dates back to 1879 and is still used to treat and prevent angina. Nitroglycerin causes vasodilation in both arteries and veins. Nitroglycerin is used in a variety of different conditions, including angina pectoris due to coronary artery disease,[L7102,L7141,L38369,L42320] peri-operative hypertension, congestive heart failure, and chronic anal fissure. It is also used to induce intraoperative hypotension.
Omeprazole {u} (Compound) causes {v} (Side Effect) Visual impairment
Visual impairment {u} (Side Effect) is caused by {v} (Compound) Nitroglycerin
Omeprazole {u} (Compound) causes {v} (Side Effect) Visual impairment
Visual impairment {u} (Side Effect) is caused by {v} (Compound) Trospium
Trospium {u} may cause a minor interaction that can limit clinical effects when taken with {v} Nitroglycerin
Omeprazole {u} (Compound) causes {v} (Side Effect) Visual disturbance
Visual disturbance {u} (Side Effect) is caused by {v} (Compound) Morphine
Morphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nitroglycerin
Omeprazole {u} (Compound) causes {v} (Side Effect) Immune system disorder
Immune system disorder {u} (Side Effect) is caused by {v} (Compound) Dicyclomine
Dicyclomine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Nitroglycerin
Omeprazole {u} (Compound) palliates {v} (Disease) esophageal cancer
esophageal cancer {u} (Disease) is associated with {v} (Gene) ALDH2
ALDH2 {u} (Gene) is bound by {v} (Compound) Nitroglycerin
Omeprazole {u} (Compound) causes {v} (Side Effect) Visual disturbance
Visual disturbance {u} (Side Effect) is caused by {v} (Compound) Bupropion
Bupropion {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nitroglycerin
Omeprazole {u} (Compound) binds {v} (Gene) ATP4A
ATP4A {u} (Gene) is associated with {v} (Disease) coronary artery disease
coronary artery disease {u} (Disease) is palliated by {v} (Compound) Nitroglycerin
Omeprazole {u} (Compound) resembles {v} (Compound) Pantoprazole
Pantoprazole {u} (Compound) causes {v} (Side Effect) Visual impairment
Visual impairment {u} (Side Effect) is caused by {v} (Compound) Nitroglycerin
Omeprazole {u} (Compound) binds {v} (Gene) CYP2C19
CYP2C19 {u} (Gene) is bound by {v} (Compound) Acetylsalicylic acid
Acetylsalicylic acid {u} may cause a minor interaction that can limit clinical effects when taken with {v} Nitroglycerin
Omeprazole {u} (Compound) resembles {v} (Compound) Lansoprazole
Lansoprazole {u} (Compound) causes {v} (Side Effect) Visual impairment
Visual impairment {u} (Side Effect) is caused by {v} (Compound) Nitroglycerin
Omeprazole (Compound) causes Visual impairment (Side Effect) and Visual impairment (Side Effect) is caused by Nitroglycerin (Compound)
Omeprazole (Compound) causes Visual impairment (Side Effect) and Visual impairment (Side Effect) is caused by Trospium (Compound) and Trospium may cause a minor interaction that can limit clinical effects when taken with Nitroglycerin
Omeprazole (Compound) causes Visual disturbance (Side Effect) and Visual disturbance (Side Effect) is caused by Morphine (Compound) and Morphine may cause a moderate interaction that could exacerbate diseases when taken with Nitroglycerin
Omeprazole (Compound) causes Immune system disorder (Side Effect) and Immune system disorder (Side Effect) is caused by Dicyclomine (Compound) and Dicyclomine may cause a minor interaction that can limit clinical effects when taken with Nitroglycerin
Omeprazole (Compound) palliates esophageal cancer (Disease) and esophageal cancer (Disease) is associated with ALDH2 (Gene) and ALDH2 (Gene) is bound by Nitroglycerin (Compound)
Omeprazole (Compound) causes Visual disturbance (Side Effect) and Visual disturbance (Side Effect) is caused by Bupropion (Compound) and Bupropion may cause a moderate interaction that could exacerbate diseases when taken with Nitroglycerin
Omeprazole (Compound) binds ATP4A (Gene) and ATP4A (Gene) is associated with coronary artery disease (Disease) and coronary artery disease (Disease) is palliated by Nitroglycerin (Compound)
Omeprazole (Compound) resembles Pantoprazole (Compound) and Pantoprazole (Compound) causes Visual impairment (Side Effect) and Visual impairment (Side Effect) is caused by Nitroglycerin (Compound)
Omeprazole (Compound) binds CYP2C19 (Gene) and CYP2C19 (Gene) is bound by Acetylsalicylic acid (Compound) and Acetylsalicylic acid may cause a minor interaction that can limit clinical effects when taken with Nitroglycerin
Omeprazole (Compound) resembles Lansoprazole (Compound) and Lansoprazole (Compound) causes Visual impairment (Side Effect) and Visual impairment (Side Effect) is caused by Nitroglycerin (Compound)