DDInter747 DDInter1759
Fludrocortisone is a synthetic mineralocorticoid used in conjunction with [hydrocortisone] to replace missing endogenous corticosteroids in patients with adrenal insufficiency.[A187169,A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and is structurally analogous to [cortisol], differing only by a fluorine atom at the 9-position of the steroid structure - this fluorination is thought to be crucial to fludrocortisone's significant mineralocorticoid potency.
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arterial blood pressure.[A1489,A1490] Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects.
Fludrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Azilsartan medoxomil
Azilsartan medoxomil {u} (Compound) resembles {v} (Compound) Telmisartan
Fludrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Losartan
Losartan {u} (Compound) resembles {v} (Compound) Telmisartan
Fludrocortisone {u} (Compound) causes {v} (Side Effect) Asthenia
Asthenia {u} (Side Effect) is caused by {v} (Compound) Telmisartan
Fludrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Azilsartan medoxomil
Azilsartan medoxomil {u} (Compound) resembles {v} (Compound) Candesartan
Candesartan {u} (Compound) resembles {v} (Compound) Telmisartan
Fludrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Losartan
Losartan {u} (Compound) resembles {v} (Compound) Candesartan
Candesartan {u} (Compound) resembles {v} (Compound) Telmisartan
Fludrocortisone {u} (Compound) causes {v} (Side Effect) Asthenia
Asthenia {u} (Side Effect) is caused by {v} (Compound) Candesartan
Candesartan {u} (Compound) resembles {v} (Compound) Telmisartan
Fludrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Losartan
Losartan {u} (Compound) resembles {v} (Compound) Olmesartan
Olmesartan {u} (Compound) resembles {v} (Compound) Telmisartan
Fludrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Azilsartan medoxomil
Azilsartan medoxomil {u} (Compound) binds {v} (Gene) AGTR1
AGTR1 {u} (Gene) is bound by {v} (Compound) Telmisartan
Fludrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Losartan
Losartan {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Telmisartan
Fludrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Empagliflozin
Empagliflozin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Azilsartan medoxomil
Azilsartan medoxomil {u} (Compound) resembles {v} (Compound) Telmisartan
Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Azilsartan medoxomil and Azilsartan medoxomil (Compound) resembles Telmisartan (Compound)
Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Losartan and Losartan (Compound) resembles Telmisartan (Compound)
Fludrocortisone (Compound) causes Asthenia (Side Effect) and Asthenia (Side Effect) is caused by Telmisartan (Compound)
Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Azilsartan medoxomil and Azilsartan medoxomil (Compound) resembles Candesartan (Compound) and Candesartan (Compound) resembles Telmisartan (Compound)
Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Losartan and Losartan (Compound) resembles Candesartan (Compound) and Candesartan (Compound) resembles Telmisartan (Compound)
Fludrocortisone (Compound) causes Asthenia (Side Effect) and Asthenia (Side Effect) is caused by Candesartan (Compound) and Candesartan (Compound) resembles Telmisartan (Compound)
Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Losartan and Losartan (Compound) resembles Olmesartan (Compound) and Olmesartan (Compound) resembles Telmisartan (Compound)
Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Azilsartan medoxomil and Azilsartan medoxomil (Compound) binds AGTR1 (Gene) and AGTR1 (Gene) is bound by Telmisartan (Compound)
Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Losartan and Losartan (Compound) treats hypertension (Disease) and hypertension (Disease) is treated by Telmisartan (Compound)
Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Empagliflozin and Empagliflozin may cause a moderate interaction that could exacerbate diseases when taken with Azilsartan medoxomil and Azilsartan medoxomil (Compound) resembles Telmisartan (Compound)