DDInter1642 DDInter350
Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Chlorambucil {u} (Compound) resembles {v} (Compound) Melphalan
Chlorambucil {u} (Compound) treats {v} (Disease) ovarian cancer
Chlorambucil {u} (Compound) binds {v} (Gene) SLCO1A2
Chlorambucil {u} (Compound) upregulates {v} (Gene) DDB2
Chlorambucil {u} (Compound) is included by {v} (Pharmacologic Class) Alkylating Activity
Chlorambucil {u} (Compound) downregulates {v} (Gene) CENPA
Chlorambucil {u} (Compound) causes {v} (Side Effect) Hyperuricaemia
Chlorambucil (Compound) resembles Melphalan (Compound)
Chlorambucil (Compound) treats ovarian cancer (Disease)
Chlorambucil (Compound) binds SLCO1A2 (Gene)
Chlorambucil (Compound) upregulates DDB2 (Gene)
Chlorambucil (Compound) is included by Alkylating Activity (Pharmacologic Class)
Chlorambucil (Compound) downregulates CENPA (Gene)
Chlorambucil (Compound) causes Hyperuricaemia (Side Effect)