DDInter781 DDInter58
Fosinopril is a phosphinic acid-containing ester prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly hydrolyzed to fosinoprilat, its principle active metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Fosinopril may be used to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and microalbuminuria or overt nephropathy.
Aluminum hydroxide is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects.
Fosinopril {u} (Compound) causes {v} (Side Effect) Infection
Infection {u} (Side Effect) is caused by {v} (Compound) Aluminum hydroxide
Fosinopril {u} (Compound) resembles {v} (Compound) Enalapril
Enalapril {u} may cause a minor interaction that can limit clinical effects when taken with {v} Aluminum hydroxide
Fosinopril {u} (Compound) causes {v} (Side Effect) Infection
Infection {u} (Side Effect) is caused by {v} (Compound) Fludrocortisone
Fludrocortisone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Aluminum hydroxide
Fosinopril {u} (Compound) resembles {v} (Compound) Enalapril
Enalapril {u} (Compound) causes {v} (Side Effect) Oedema
Oedema {u} (Side Effect) is caused by {v} (Compound) Aluminum hydroxide
Fosinopril {u} (Compound) resembles {v} (Compound) Cilazapril
Cilazapril {u} (Compound) causes {v} (Side Effect) Oedema
Oedema {u} (Side Effect) is caused by {v} (Compound) Aluminum hydroxide
Fosinopril {u} (Compound) resembles {v} (Compound) Cilazapril
Cilazapril {u} (Compound) resembles {v} (Compound) Moexipril
Moexipril {u} may cause a minor interaction that can limit clinical effects when taken with {v} Aluminum hydroxide
Fosinopril {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Moexipril
Moexipril {u} may cause a minor interaction that can limit clinical effects when taken with {v} Aluminum hydroxide
Fosinopril {u} (Compound) resembles {v} (Compound) Enalapril
Enalapril {u} (Compound) resembles {v} (Compound) Moexipril
Moexipril {u} may cause a minor interaction that can limit clinical effects when taken with {v} Aluminum hydroxide
Fosinopril {u} (Compound) binds {v} (Gene) SLC15A2
SLC15A2 {u} (Gene) is bound by {v} (Compound) Moexipril
Moexipril {u} may cause a minor interaction that can limit clinical effects when taken with {v} Aluminum hydroxide
Fosinopril {u} (Compound) resembles {v} (Compound) Cilazapril
Cilazapril {u} (Compound) resembles {v} (Compound) Quinapril
Quinapril {u} may cause a minor interaction that can limit clinical effects when taken with {v} Aluminum hydroxide
Fosinopril (Compound) causes Infection (Side Effect) and Infection (Side Effect) is caused by Aluminum hydroxide (Compound)
Fosinopril (Compound) resembles Enalapril (Compound) and Enalapril may cause a minor interaction that can limit clinical effects when taken with Aluminum hydroxide
Fosinopril (Compound) causes Infection (Side Effect) and Infection (Side Effect) is caused by Fludrocortisone (Compound) and Fludrocortisone may cause a minor interaction that can limit clinical effects when taken with Aluminum hydroxide
Fosinopril (Compound) resembles Enalapril (Compound) and Enalapril (Compound) causes Oedema (Side Effect) and Oedema (Side Effect) is caused by Aluminum hydroxide (Compound)
Fosinopril (Compound) resembles Cilazapril (Compound) and Cilazapril (Compound) causes Oedema (Side Effect) and Oedema (Side Effect) is caused by Aluminum hydroxide (Compound)
Fosinopril (Compound) resembles Cilazapril (Compound) and Cilazapril (Compound) resembles Moexipril (Compound) and Moexipril may cause a minor interaction that can limit clinical effects when taken with Aluminum hydroxide
Fosinopril (Compound) treats hypertension (Disease) and hypertension (Disease) is treated by Moexipril (Compound) and Moexipril may cause a minor interaction that can limit clinical effects when taken with Aluminum hydroxide
Fosinopril (Compound) resembles Enalapril (Compound) and Enalapril (Compound) resembles Moexipril (Compound) and Moexipril may cause a minor interaction that can limit clinical effects when taken with Aluminum hydroxide
Fosinopril (Compound) binds SLC15A2 (Gene) and SLC15A2 (Gene) is bound by Moexipril (Compound) and Moexipril may cause a minor interaction that can limit clinical effects when taken with Aluminum hydroxide
Fosinopril (Compound) resembles Cilazapril (Compound) and Cilazapril (Compound) resembles Quinapril (Compound) and Quinapril may cause a minor interaction that can limit clinical effects when taken with Aluminum hydroxide