DDInter1191 DDInter1759
Methylprednisolone is a [prednisolone] derivative glucocorticoid with higher potency than [prednisone]. It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with long-term immunosuppression. The efficacy of methylprednisolone in novel coronavirus pneumonia is being investigated further in clinical trials.
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arterial blood pressure.[A1489,A1490] Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects.
Methylprednisolone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Azilsartan medoxomil
Azilsartan medoxomil {u} (Compound) resembles {v} (Compound) Telmisartan
Methylprednisolone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Losartan
Losartan {u} (Compound) resembles {v} (Compound) Telmisartan
Methylprednisolone {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Telmisartan
Methylprednisolone {u} (Compound) causes {v} (Side Effect) Rash
Rash {u} (Side Effect) is caused by {v} (Compound) Telmisartan
Methylprednisolone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Azilsartan medoxomil
Azilsartan medoxomil {u} (Compound) resembles {v} (Compound) Candesartan
Candesartan {u} (Compound) resembles {v} (Compound) Telmisartan
Methylprednisolone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Losartan
Losartan {u} (Compound) resembles {v} (Compound) Candesartan
Candesartan {u} (Compound) resembles {v} (Compound) Telmisartan
Methylprednisolone {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Candesartan
Candesartan {u} (Compound) resembles {v} (Compound) Telmisartan
Methylprednisolone {u} (Compound) causes {v} (Side Effect) Rash
Rash {u} (Side Effect) is caused by {v} (Compound) Candesartan
Candesartan {u} (Compound) resembles {v} (Compound) Telmisartan
Methylprednisolone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Losartan
Losartan {u} (Compound) resembles {v} (Compound) Olmesartan
Olmesartan {u} (Compound) resembles {v} (Compound) Telmisartan
Methylprednisolone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Azilsartan medoxomil
Azilsartan medoxomil {u} (Compound) binds {v} (Gene) AGTR1
AGTR1 {u} (Gene) is bound by {v} (Compound) Telmisartan
Methylprednisolone may cause a moderate interaction that could exacerbate diseases when taken with Azilsartan medoxomil and Azilsartan medoxomil (Compound) resembles Telmisartan (Compound)
Methylprednisolone may cause a moderate interaction that could exacerbate diseases when taken with Losartan and Losartan (Compound) resembles Telmisartan (Compound)
Methylprednisolone (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Telmisartan (Compound)
Methylprednisolone (Compound) causes Rash (Side Effect) and Rash (Side Effect) is caused by Telmisartan (Compound)
Methylprednisolone may cause a moderate interaction that could exacerbate diseases when taken with Azilsartan medoxomil and Azilsartan medoxomil (Compound) resembles Candesartan (Compound) and Candesartan (Compound) resembles Telmisartan (Compound)
Methylprednisolone may cause a moderate interaction that could exacerbate diseases when taken with Losartan and Losartan (Compound) resembles Candesartan (Compound) and Candesartan (Compound) resembles Telmisartan (Compound)
Methylprednisolone (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Candesartan (Compound) and Candesartan (Compound) resembles Telmisartan (Compound)
Methylprednisolone (Compound) causes Rash (Side Effect) and Rash (Side Effect) is caused by Candesartan (Compound) and Candesartan (Compound) resembles Telmisartan (Compound)
Methylprednisolone may cause a moderate interaction that could exacerbate diseases when taken with Losartan and Losartan (Compound) resembles Olmesartan (Compound) and Olmesartan (Compound) resembles Telmisartan (Compound)
Methylprednisolone may cause a moderate interaction that could exacerbate diseases when taken with Azilsartan medoxomil and Azilsartan medoxomil (Compound) binds AGTR1 (Gene) and AGTR1 (Gene) is bound by Telmisartan (Compound)