DDInter1462 DDInter1676
A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.
Siponimod, also known as _Mayzent_, by Novartis, is a new drug formulated for the management of Multiple Sclerosis (MS). It was approved by the FDA on March 26, 2019 and by Health Canada on February 20, 2020. This drug is considered a _sphingosine-1-phosphate (S1P) receptor modulator_ and is thought to play a role in suppressing the central nervous system inflammation that is associated with MS [FDA label]. Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system that is chronic and inflammatory, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of life. Symptoms may include but are not limited to fatigue, gait changes, bowel or bladder dysfunction, abnormal muscle twitching, vision disturbance, and depressing or mood swings. MS is one of the most common causes of neurological disability in young adults and is found to occur more frequently in women than in men.[A176474,L5792]
Physostigmine {u} (Compound) treats {v} (Disease) glaucoma
Physostigmine {u} (Compound) binds {v} (Gene) ACHE
Physostigmine {u} (Compound) causes {v} (Side Effect) Convulsion
Physostigmine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nebivolol
Physostigmine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Succinylcholine
Physostigmine {u} may lead to a major life threatening interaction when taken with {v} Iohexol
Physostigmine {u} may lead to a major life threatening interaction when taken with {v} Tramadol
Physostigmine (Compound) treats glaucoma (Disease)
Physostigmine (Compound) binds ACHE (Gene)
Physostigmine (Compound) causes Convulsion (Side Effect)
Physostigmine may cause a moderate interaction that could exacerbate diseases when taken with Nebivolol
Physostigmine may cause a moderate interaction that could exacerbate diseases when taken with Succinylcholine
Physostigmine may lead to a major life threatening interaction when taken with Iohexol
Physostigmine may lead to a major life threatening interaction when taken with Tramadol