DDInter779 DDInter704
An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and not on the mTORC2 protein.
Foscarnet {u} may lead to a major life threatening interaction when taken with {v} Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Everolimus
Foscarnet {u} (Compound) causes {v} (Side Effect) Pneumothorax
Pneumothorax {u} (Side Effect) is caused by {v} (Compound) Everolimus
Foscarnet {u} may lead to a major life threatening interaction when taken with {v} Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Pimecrolimus
Pimecrolimus {u} (Compound) resembles {v} (Compound) Everolimus
Foscarnet {u} (Compound) causes {v} (Side Effect) Pneumothorax
Pneumothorax {u} (Side Effect) is caused by {v} (Compound) Tacrolimus
Tacrolimus {u} (Compound) resembles {v} (Compound) Everolimus
Foscarnet {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Pimecrolimus
Pimecrolimus {u} (Compound) resembles {v} (Compound) Everolimus
Foscarnet {u} (Compound) binds {v} (Gene) SLC22A6
SLC22A6 {u} (Gene) covaries with {v} (Gene) HMOX1
HMOX1 {u} (Gene) is upregulated by {v} (Compound) Everolimus
Foscarnet {u} may lead to a major life threatening interaction when taken with {v} Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Temsirolimus {u} (Compound) resembles {v} (Compound) Everolimus
Foscarnet {u} (Compound) binds {v} (Gene) SLC16A1
SLC16A1 {u} (Gene) regulates {v} (Gene) DTYMK
DTYMK {u} (Gene) is downregulated by {v} (Compound) Everolimus
Foscarnet {u} (Compound) binds {v} (Gene) SLC16A1
SLC16A1 {u} (Gene) regulates {v} (Gene) PNP
PNP {u} (Gene) is upregulated by {v} (Compound) Everolimus
Foscarnet {u} may lead to a major life threatening interaction when taken with {v} Sirolimus
Sirolimus {u} (Compound) binds {v} (Gene) FKBP1A
FKBP1A {u} (Gene) is bound by {v} (Compound) Everolimus
Foscarnet may lead to a major life threatening interaction when taken with Sirolimus and Sirolimus (Compound) resembles Everolimus (Compound)
Foscarnet (Compound) causes Pneumothorax (Side Effect) and Pneumothorax (Side Effect) is caused by Everolimus (Compound)
Foscarnet may lead to a major life threatening interaction when taken with Sirolimus and Sirolimus (Compound) resembles Pimecrolimus (Compound) and Pimecrolimus (Compound) resembles Everolimus (Compound)
Foscarnet (Compound) causes Pneumothorax (Side Effect) and Pneumothorax (Side Effect) is caused by Tacrolimus (Compound) and Tacrolimus (Compound) resembles Everolimus (Compound)
Foscarnet (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Pimecrolimus (Compound) and Pimecrolimus (Compound) resembles Everolimus (Compound)
Foscarnet (Compound) binds SLC22A6 (Gene) and SLC22A6 (Gene) covaries with HMOX1 (Gene) and HMOX1 (Gene) is upregulated by Everolimus (Compound)
Foscarnet may lead to a major life threatening interaction when taken with Sirolimus and Sirolimus (Compound) resembles Temsirolimus (Compound) and Temsirolimus (Compound) resembles Everolimus (Compound)
Foscarnet (Compound) binds SLC16A1 (Gene) and SLC16A1 (Gene) regulates DTYMK (Gene) and DTYMK (Gene) is downregulated by Everolimus (Compound)
Foscarnet (Compound) binds SLC16A1 (Gene) and SLC16A1 (Gene) regulates PNP (Gene) and PNP (Gene) is upregulated by Everolimus (Compound)
Foscarnet may lead to a major life threatening interaction when taken with Sirolimus and Sirolimus (Compound) binds FKBP1A (Gene) and FKBP1A (Gene) is bound by Everolimus (Compound)