DDInter1244 DDInter790
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine], and [oxycodone]. Morphine was granted FDA approval in 1941.
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of water from the body. Furosemide has a fast onset and short duration of action and has been used safely and effectively in both pediatric and adult patients. The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential. In addition to oral formulations, the solution for intravenous and intramuscular administration is also available, which is typically limited to patients who are unable to take oral medication or for patients in emergency clinical situations.
Morphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Morphine {u} (Compound) palliates {v} (Disease) coronary artery disease
coronary artery disease {u} (Disease) is treated by {v} (Compound) Furosemide
Morphine {u} (Compound) causes {v} (Side Effect) Drowsiness
Drowsiness {u} (Side Effect) is caused by {v} (Compound) Furosemide
Morphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Bumetanide
Bumetanide {u} (Compound) resembles {v} (Compound) Furosemide
Morphine {u} (Compound) palliates {v} (Disease) coronary artery disease
coronary artery disease {u} (Disease) is associated with {v} (Gene) CA5B
CA5B {u} (Gene) is bound by {v} (Compound) Furosemide
Morphine {u} (Compound) causes {v} (Side Effect) Drowsiness
Drowsiness {u} (Side Effect) is caused by {v} (Compound) Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Morphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Furosemide
Morphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxcarbazepine
Oxcarbazepine {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Morphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) binds {v} (Gene) CA5A
CA5A {u} (Gene) is bound by {v} (Compound) Furosemide
Morphine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Morphine may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) resembles Furosemide (Compound)
Morphine (Compound) palliates coronary artery disease (Disease) and coronary artery disease (Disease) is treated by Furosemide (Compound)
Morphine (Compound) causes Drowsiness (Side Effect) and Drowsiness (Side Effect) is caused by Furosemide (Compound)
Morphine may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) resembles Bumetanide (Compound) and Bumetanide (Compound) resembles Furosemide (Compound)
Morphine (Compound) palliates coronary artery disease (Disease) and coronary artery disease (Disease) is associated with CA5B (Gene) and CA5B (Gene) is bound by Furosemide (Compound)
Morphine (Compound) causes Drowsiness (Side Effect) and Drowsiness (Side Effect) is caused by Indapamide (Compound) and Indapamide (Compound) resembles Furosemide (Compound)
Morphine may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) treats hypertension (Disease) and hypertension (Disease) is treated by Furosemide (Compound)
Morphine may cause a moderate interaction that could exacerbate diseases when taken with Oxcarbazepine and Oxcarbazepine (Compound) resembles Indapamide (Compound) and Indapamide (Compound) resembles Furosemide (Compound)
Morphine may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) binds CA5A (Gene) and CA5A (Gene) is bound by Furosemide (Compound)
Morphine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Indapamide (Compound) and Indapamide (Compound) resembles Furosemide (Compound)