DDInter293 DDInter1652
Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965. Aside from the above uses, this drug is also given to control the symptoms of bipolar 1. Interestingly, carbamazepine was the first anticonvulsant used to treat individuals with bipolar disorder.
Secukinumab is a fully human monoclonal IgG1/κ antibody against interleukin-17A (IL-17A), a proinflammatory cytokine implicated in various chronic immune-mediated inflammatory disorders, such as plaque psoriasis. By blocking the actions of IL-17A, secukinumab works to inhibit the pro-inflammatory pathways that drive immune-mediated inflammatory disorders. Following its first global approval in Japan in December 2014, secukinumab was approved by the European Commission on January 15, 2015, and by the FDA a few days after (January 21, 2015). It is currently approved to treat a number of chronic inflammatory conditions, such as plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, and hidradenitis suppurativa.[L39600,L42280,L48771]
Carbamazepine {u} (Compound) resembles {v} (Compound) Magnesium salicylate
Carbamazepine {u} (Compound) resembles {v} (Compound) Modafinil
Carbamazepine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methdilazine
Carbamazepine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cyproheptadine
Carbamazepine {u} (Compound) treats {v} (Disease) epilepsy syndrome
Carbamazepine {u} (Compound) binds {v} (Gene) SCN9A
Carbamazepine {u} (Compound) upregulates {v} (Gene) PLCB3
Carbamazepine {u} (Compound) palliates {v} (Disease) bipolar disorder
Carbamazepine {u} (Compound) is included by {v} (Pharmacologic Class) Cytochrome P450 1A2 Inducers
Carbamazepine {u} (Compound) downregulates {v} (Gene) TIMM9
Carbamazepine (Compound) resembles Magnesium salicylate (Compound)
Carbamazepine (Compound) resembles Modafinil (Compound)
Carbamazepine may cause a moderate interaction that could exacerbate diseases when taken with Methdilazine
Carbamazepine may cause a moderate interaction that could exacerbate diseases when taken with Cyproheptadine
Carbamazepine (Compound) treats epilepsy syndrome (Disease)
Carbamazepine (Compound) binds SCN9A (Gene)
Carbamazepine (Compound) upregulates PLCB3 (Gene)
Carbamazepine (Compound) palliates bipolar disorder (Disease)
Carbamazepine (Compound) is included by Cytochrome P450 1A2 Inducers (Pharmacologic Class)
Carbamazepine (Compound) downregulates TIMM9 (Gene)