DDInter1205 DDInter154
An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. (Martindale, The Extra Pharmacopoeia, 30th ed)
Azelastine is a phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position. It has a role as a H1-receptor antagonist, an anti-allergic agent, an anti-asthmatic drug, a bronchodilator agent, a platelet aggregation inhibitor and an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. It is a member of phthalazines, a tertiary amino compound and a member of monochlorobenzenes.
Metyrosine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clemastine
Clemastine {u} (Compound) resembles {v} (Compound) Azelastine
Metyrosine {u} (Compound) causes {v} (Side Effect) Feeling abnormal
Feeling abnormal {u} (Side Effect) is caused by {v} (Compound) Azelastine
Metyrosine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clemastine
Clemastine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) Azelastine
Metyrosine {u} (Compound) causes {v} (Side Effect) Feeling abnormal
Feeling abnormal {u} (Side Effect) is caused by {v} (Compound) Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) Azelastine
Metyrosine {u} (Compound) resembles {v} (Compound) Ibuprofen
Ibuprofen {u} (Compound) binds {v} (Gene) CYP2C8
CYP2C8 {u} (Gene) is bound by {v} (Compound) Azelastine
Metyrosine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clemastine
Clemastine {u} (Compound) resembles {v} (Compound) Buclizine
Buclizine {u} (Compound) resembles {v} (Compound) Azelastine
Metyrosine {u} (Compound) resembles {v} (Compound) Carbidopa
Carbidopa {u} (Compound) upregulates {v} (Gene) EPCAM
EPCAM {u} (Gene) is upregulated by {v} (Compound) Azelastine
Metyrosine {u} (Compound) resembles {v} (Compound) Carbidopa
Carbidopa {u} (Compound) downregulates {v} (Gene) NME1
NME1 {u} (Gene) is downregulated by {v} (Compound) Azelastine
Metyrosine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clemastine
Clemastine {u} (Compound) resembles {v} (Compound) Cloperastine
Cloperastine {u} (Compound) resembles {v} (Compound) Azelastine
Metyrosine {u} (Compound) binds {v} (Gene) TH
TH {u} (Gene) regulates {v} (Gene) WIF1
WIF1 {u} (Gene) is upregulated by {v} (Compound) Azelastine
Metyrosine may cause a moderate interaction that could exacerbate diseases when taken with Clemastine and Clemastine (Compound) resembles Azelastine (Compound)
Metyrosine (Compound) causes Feeling abnormal (Side Effect) and Feeling abnormal (Side Effect) is caused by Azelastine (Compound)
Metyrosine may cause a moderate interaction that could exacerbate diseases when taken with Clemastine and Clemastine may cause a moderate interaction that could exacerbate diseases when taken with Loxapine and Loxapine (Compound) resembles Azelastine (Compound)
Metyrosine (Compound) causes Feeling abnormal (Side Effect) and Feeling abnormal (Side Effect) is caused by Loxapine (Compound) and Loxapine (Compound) resembles Azelastine (Compound)
Metyrosine (Compound) resembles Ibuprofen (Compound) and Ibuprofen (Compound) binds CYP2C8 (Gene) and CYP2C8 (Gene) is bound by Azelastine (Compound)
Metyrosine may cause a moderate interaction that could exacerbate diseases when taken with Clemastine and Clemastine (Compound) resembles Buclizine (Compound) and Buclizine (Compound) resembles Azelastine (Compound)
Metyrosine (Compound) resembles Carbidopa (Compound) and Carbidopa (Compound) upregulates EPCAM (Gene) and EPCAM (Gene) is upregulated by Azelastine (Compound)
Metyrosine (Compound) resembles Carbidopa (Compound) and Carbidopa (Compound) downregulates NME1 (Gene) and NME1 (Gene) is downregulated by Azelastine (Compound)
Metyrosine may cause a moderate interaction that could exacerbate diseases when taken with Clemastine and Clemastine (Compound) resembles Cloperastine (Compound) and Cloperastine (Compound) resembles Azelastine (Compound)
Metyrosine (Compound) binds TH (Gene) and TH (Gene) regulates WIF1 (Gene) and WIF1 (Gene) is upregulated by Azelastine (Compound)