DDInter1768 DDInter556
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell wall synthesis pathway.[A1279,A1281,L9068] Terbinafine hydrochloride was granted FDA approval on 30 December 1992.
Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough. It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more effective antitussive agent to help reduce the spread of airborne infectious diseases such as tuburculosis. It was marketed in 1911.
Terbinafine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Galantamine
Galantamine {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Terbinafine {u} may lead to a major life threatening interaction when taken with {v} Dextromethorphan
Dextromethorphan {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Terbinafine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Morphine
Morphine {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Terbinafine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Dihydrocodeine
Terbinafine {u} (Compound) causes {v} (Side Effect) Confusional state
Confusional state {u} (Side Effect) is caused by {v} (Compound) Dihydrocodeine
Terbinafine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Galantamine
Galantamine {u} (Compound) resembles {v} (Compound) Hydrocodone
Hydrocodone {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Terbinafine {u} may lead to a major life threatening interaction when taken with {v} Dextromethorphan
Dextromethorphan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxymorphone
Oxymorphone {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Terbinafine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Morphine
Morphine {u} (Compound) resembles {v} (Compound) Galantamine
Galantamine {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Terbinafine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Galantamine
Galantamine {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Terbinafine {u} (Compound) causes {v} (Side Effect) Confusional state
Confusional state {u} (Side Effect) is caused by {v} (Compound) Galantamine
Galantamine {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Terbinafine may cause a moderate interaction that could exacerbate diseases when taken with Galantamine and Galantamine (Compound) resembles Dihydrocodeine (Compound)
Terbinafine may lead to a major life threatening interaction when taken with Dextromethorphan and Dextromethorphan (Compound) resembles Dihydrocodeine (Compound)
Terbinafine may cause a moderate interaction that could exacerbate diseases when taken with Morphine and Morphine (Compound) resembles Dihydrocodeine (Compound)
Terbinafine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Dihydrocodeine (Compound)
Terbinafine (Compound) causes Confusional state (Side Effect) and Confusional state (Side Effect) is caused by Dihydrocodeine (Compound)
Terbinafine may cause a moderate interaction that could exacerbate diseases when taken with Galantamine and Galantamine (Compound) resembles Hydrocodone (Compound) and Hydrocodone (Compound) resembles Dihydrocodeine (Compound)
Terbinafine may lead to a major life threatening interaction when taken with Dextromethorphan and Dextromethorphan may cause a moderate interaction that could exacerbate diseases when taken with Oxymorphone and Oxymorphone (Compound) resembles Dihydrocodeine (Compound)
Terbinafine may cause a moderate interaction that could exacerbate diseases when taken with Morphine and Morphine (Compound) resembles Galantamine (Compound) and Galantamine (Compound) resembles Dihydrocodeine (Compound)
Terbinafine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Galantamine (Compound) and Galantamine (Compound) resembles Dihydrocodeine (Compound)
Terbinafine (Compound) causes Confusional state (Side Effect) and Confusional state (Side Effect) is caused by Galantamine (Compound) and Galantamine (Compound) resembles Dihydrocodeine (Compound)