DDInter1523 DDInter1016
A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose]. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. [sucrose]). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in patients with cirrhosis.[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.
Probucol {u} (Compound) binds {v} (Gene) CES1
Probucol {u} (Compound) upregulates {v} (Gene) RRS1
Probucol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metronidazole
Probucol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxaliplatin
Probucol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Encorafenib
Probucol {u} may lead to a major life threatening interaction when taken with {v} Hydroxychloroquine
Probucol {u} may lead to a major life threatening interaction when taken with {v} Toremifene
Probucol (Compound) binds CES1 (Gene)
Probucol (Compound) upregulates RRS1 (Gene)
Probucol may cause a minor interaction that can limit clinical effects when taken with Metronidazole
Probucol may cause a moderate interaction that could exacerbate diseases when taken with Oxaliplatin
Probucol may cause a moderate interaction that could exacerbate diseases when taken with Encorafenib
Probucol may lead to a major life threatening interaction when taken with Hydroxychloroquine
Probucol may lead to a major life threatening interaction when taken with Toremifene