DDInter395 DDInter1845
An ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders (From AMA Drug Evaluations Annual, 1994, p311). Tranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine with the chiral centers both located on the cylopropane ring. An irreversible monoamine oxidase inhibitor that is used as an antidepressant (INN tranylcypromine).
Clemastine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ethotoin
Ethotoin {u} (Compound) resembles {v} (Compound) Tranylcypromine
Clemastine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phensuximide
Phensuximide {u} (Compound) resembles {v} (Compound) Tranylcypromine
Clemastine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Tranylcypromine
Clemastine {u} (Compound) causes {v} (Side Effect) Asthenia
Asthenia {u} (Side Effect) is caused by {v} (Compound) Tranylcypromine
Clemastine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ethotoin
Ethotoin {u} (Compound) resembles {v} (Compound) Phenmetrazine
Phenmetrazine {u} (Compound) resembles {v} (Compound) Tranylcypromine
Clemastine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phensuximide
Phensuximide {u} (Compound) resembles {v} (Compound) Ethotoin
Ethotoin {u} (Compound) resembles {v} (Compound) Tranylcypromine
Clemastine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenelzine
Phenelzine {u} may lead to a major life threatening interaction when taken with {v} Phentermine
Phentermine {u} (Compound) resembles {v} (Compound) Tranylcypromine
Clemastine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Benzyl alcohol
Benzyl alcohol {u} (Compound) resembles {v} (Compound) Tranylcypromine
Clemastine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Phentermine
Phentermine {u} (Compound) resembles {v} (Compound) Tranylcypromine
Clemastine {u} (Compound) causes {v} (Side Effect) Asthenia
Asthenia {u} (Side Effect) is caused by {v} (Compound) Phentermine
Phentermine {u} (Compound) resembles {v} (Compound) Tranylcypromine
Clemastine may cause a moderate interaction that could exacerbate diseases when taken with Ethotoin and Ethotoin (Compound) resembles Tranylcypromine (Compound)
Clemastine may cause a moderate interaction that could exacerbate diseases when taken with Phensuximide and Phensuximide (Compound) resembles Tranylcypromine (Compound)
Clemastine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Tranylcypromine (Compound)
Clemastine (Compound) causes Asthenia (Side Effect) and Asthenia (Side Effect) is caused by Tranylcypromine (Compound)
Clemastine may cause a moderate interaction that could exacerbate diseases when taken with Ethotoin and Ethotoin (Compound) resembles Phenmetrazine (Compound) and Phenmetrazine (Compound) resembles Tranylcypromine (Compound)
Clemastine may cause a moderate interaction that could exacerbate diseases when taken with Phensuximide and Phensuximide (Compound) resembles Ethotoin (Compound) and Ethotoin (Compound) resembles Tranylcypromine (Compound)
Clemastine may cause a moderate interaction that could exacerbate diseases when taken with Phenelzine and Phenelzine may lead to a major life threatening interaction when taken with Phentermine and Phentermine (Compound) resembles Tranylcypromine (Compound)
Clemastine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Benzyl alcohol (Compound) and Benzyl alcohol (Compound) resembles Tranylcypromine (Compound)
Clemastine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Phentermine (Compound) and Phentermine (Compound) resembles Tranylcypromine (Compound)
Clemastine (Compound) causes Asthenia (Side Effect) and Asthenia (Side Effect) is caused by Phentermine (Compound) and Phentermine (Compound) resembles Tranylcypromine (Compound)