DDInter1864 DDInter278
Triethylenetatramine (TETA), also known as trientine, is a potent and selective copper (II)-selective chelator. It is a structural analog of linear polyamine compounds, [spermidine] and [spermine]. TETA was first developed in Germany in 1861 and its chelating properties were first recognized in 1925. Initially approved by the FDA in 1985 as a second-line treatment for Wilson's disease, TETA is currently indicated to treat adults with stable Wilson’s disease who are de-coppered and tolerant to [penicillamine]. TETA has been investigated in clinical trials for the treatment of heart failure in patients with diabetes.[A18804,A19332,A19333,A19334,A19335]
Calcium lactate is a salt that consists of two lactate anions for each calcium cation (Ca2+). It is prepared commercially by the neutralization of lactic acid with calcium carbonate or calcium hydroxide. Approved by the FDA as a direct food substance affirmed as generally recognized as safe, calcium lactate is used as a firming agent, flavoring agent, leavening agent, stabilizer, and thickener . Calcium lactate is also found in daily dietary supplements as a source of calcium. It is also available in various hydrate forms, where calcium lactate pentahydrate is the most common.
Triethylenetetramine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Zinc gluconate
Triethylenetetramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Calcium gluconate
Triethylenetetramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Magnesium oxide
Triethylenetetramine may cause a minor interaction that can limit clinical effects when taken with Zinc gluconate
Triethylenetetramine may cause a moderate interaction that could exacerbate diseases when taken with Calcium gluconate
Triethylenetetramine may cause a moderate interaction that could exacerbate diseases when taken with Magnesium oxide