DDInter790 DDInter298
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of water from the body. Furosemide has a fast onset and short duration of action and has been used safely and effectively in both pediatric and adult patients. The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential. In addition to oral formulations, the solution for intravenous and intramuscular administration is also available, which is typically limited to patients who are unable to take oral medication or for patients in emergency clinical situations.
Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma. Early clinical studies of carboplatin were performed in 1982. Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.
Furosemide {u} (Compound) binds {v} (Gene) ABCC2
ABCC2 {u} (Gene) is bound by {v} (Compound) Carboplatin
Furosemide {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Carboplatin
Furosemide {u} (Compound) binds {v} (Gene) ABCC2
ABCC2 {u} (Gene) is associated with {v} (Disease) esophageal cancer
esophageal cancer {u} (Disease) is treated by {v} (Compound) Carboplatin
Furosemide {u} (Compound) binds {v} (Gene) CA14
CA14 {u} (Gene) is downregulated by {v} (Disease) ovarian cancer
ovarian cancer {u} (Disease) is treated by {v} (Compound) Carboplatin
Furosemide {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is associated with {v} (Gene) GSTM1
GSTM1 {u} (Gene) is bound by {v} (Compound) Carboplatin
Furosemide {u} (Compound) palliates {v} (Disease) chronic kidney failure
chronic kidney failure {u} (Disease) is associated with {v} (Gene) ABCC2
ABCC2 {u} (Gene) is bound by {v} (Compound) Carboplatin
Furosemide {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Carboplatin
Furosemide (Compound) binds ABCC2 (Gene) and ABCC2 (Gene) is bound by Carboplatin (Compound)
Furosemide (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Carboplatin (Compound)
Furosemide (Compound) binds ABCC2 (Gene) and ABCC2 (Gene) is associated with esophageal cancer (Disease) and esophageal cancer (Disease) is treated by Carboplatin (Compound)
Furosemide (Compound) binds CA14 (Gene) and CA14 (Gene) is downregulated by ovarian cancer (Disease) and ovarian cancer (Disease) is treated by Carboplatin (Compound)
Furosemide (Compound) treats hypertension (Disease) and hypertension (Disease) is associated with GSTM1 (Gene) and GSTM1 (Gene) is bound by Carboplatin (Compound)
Furosemide (Compound) palliates chronic kidney failure (Disease) and chronic kidney failure (Disease) is associated with ABCC2 (Gene) and ABCC2 (Gene) is bound by Carboplatin (Compound)
Furosemide (Compound) resembles Indapamide (Compound) and Indapamide (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Carboplatin (Compound)