DDInter690 DDInter411
A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.
A benzodiazepine used to treat various seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop.[FDA Label][L5572,F3763,F3787,F3796] The agent has also been indicated for treating panic disorder.[FDA Label][A175438,L5572,F3763,F3787,F3796] The mechanism of action appears to involve the enhancement of gamma-aminobutyric acid receptor responses.[FDA Label][A175438,A175441,L5572,F3763,F3787,F3796] Since being first patented in 1960 and then released for sale from Roche in the US in 1975,[T469,T472] clonazepam has experienced a storied history in the treatment of the aforementioned medical conditions. Now available as a generic medication, the agent continues to see exceptionally high use as millions of prescriptions are written for the medication internationally every year. Unfortunately, however, like most benzodiazepines, clonazepam use has also been associated with recreational use and drug abuse.[FDA Label][L5572,F3763,F3787,F3796]
Ethanol {u} (Compound) binds {v} (Gene) GABRA1
GABRA1 {u} (Gene) is bound by {v} (Compound) Clonazepam
Ethanol {u} (Compound) binds {v} (Gene) GABRA1
GABRA1 {u} (Gene) is bound by {v} (Compound) Nitrazepam
Nitrazepam {u} (Compound) resembles {v} (Compound) Clonazepam
Ethanol {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Diphenhydramine
Diphenhydramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clonazepam
Ethanol {u} (Compound) binds {v} (Gene) GABRA1
GABRA1 {u} (Gene) is bound by {v} (Compound) Diazepam
Diazepam {u} (Compound) resembles {v} (Compound) Clonazepam
Ethanol {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Aprepitant
Aprepitant {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clonazepam
Ethanol {u} (Compound) binds {v} (Gene) CYP1A1
CYP1A1 {u} (Gene) is bound by {v} (Compound) Theophylline
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Clonazepam
Ethanol {u} (Compound) binds {v} (Gene) CYP2C19
CYP2C19 {u} (Gene) is associated with {v} (Disease) epilepsy syndrome
epilepsy syndrome {u} (Disease) is treated by {v} (Compound) Clonazepam
Ethanol {u} (Compound) binds {v} (Gene) CYP2E1
CYP2E1 {u} (Gene) is associated with {v} (Disease) Parkinson's disease
Parkinson's disease {u} (Disease) is palliated by {v} (Compound) Clonazepam
Ethanol {u} (Compound) binds {v} (Gene) GABRA1
GABRA1 {u} (Gene) interacts with {v} (Gene) GABRG2
GABRG2 {u} (Gene) is bound by {v} (Compound) Clonazepam
Ethanol {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Morphine
Morphine {u} may lead to a major life threatening interaction when taken with {v} Clonazepam
Ethanol (Compound) binds GABRA1 (Gene) and GABRA1 (Gene) is bound by Clonazepam (Compound)
Ethanol (Compound) binds GABRA1 (Gene) and GABRA1 (Gene) is bound by Nitrazepam (Compound) and Nitrazepam (Compound) resembles Clonazepam (Compound)
Ethanol (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Diphenhydramine (Compound) and Diphenhydramine may cause a moderate interaction that could exacerbate diseases when taken with Clonazepam
Ethanol (Compound) binds GABRA1 (Gene) and GABRA1 (Gene) is bound by Diazepam (Compound) and Diazepam (Compound) resembles Clonazepam (Compound)
Ethanol (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Aprepitant (Compound) and Aprepitant may cause a moderate interaction that could exacerbate diseases when taken with Clonazepam
Ethanol (Compound) binds CYP1A1 (Gene) and CYP1A1 (Gene) is bound by Theophylline (Compound) and Theophylline may cause a minor interaction that can limit clinical effects when taken with Clonazepam
Ethanol (Compound) binds CYP2C19 (Gene) and CYP2C19 (Gene) is associated with epilepsy syndrome (Disease) and epilepsy syndrome (Disease) is treated by Clonazepam (Compound)
Ethanol (Compound) binds CYP2E1 (Gene) and CYP2E1 (Gene) is associated with Parkinson's disease (Disease) and Parkinson's disease (Disease) is palliated by Clonazepam (Compound)
Ethanol (Compound) binds GABRA1 (Gene) and GABRA1 (Gene) interacts with GABRG2 (Gene) and GABRG2 (Gene) is bound by Clonazepam (Compound)
Ethanol (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Morphine (Compound) and Morphine may lead to a major life threatening interaction when taken with Clonazepam