DDInter458 DDInter720
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus _Beauveria nivea_. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
A dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.
Cyclosporine {u} (Compound) causes {v} (Side Effect) Creatinine increased
Creatinine increased {u} (Side Effect) is caused by {v} (Compound) Fenoldopam
Cyclosporine {u} (Compound) causes {v} (Side Effect) Haemorrhage
Haemorrhage {u} (Side Effect) is caused by {v} (Compound) Dexamethasone
Dexamethasone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fenoldopam
Cyclosporine {u} (Compound) causes {v} (Side Effect) Vomiting
Vomiting {u} (Side Effect) is caused by {v} (Compound) Phentolamine
Phentolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fenoldopam
Cyclosporine {u} (Compound) treats {v} (Disease) focal segmental glomerulosclerosis
focal segmental glomerulosclerosis {u} (Disease) resembles {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Fenoldopam
Cyclosporine {u} (Compound) downregulates {v} (Gene) BIRC5
BIRC5 {u} (Gene) is associated with {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Fenoldopam
Cyclosporine {u} (Compound) treats {v} (Disease) focal segmental glomerulosclerosis
focal segmental glomerulosclerosis {u} (Disease) is associated with {v} (Gene) SPP1
SPP1 {u} (Gene) is upregulated by {v} (Compound) Fenoldopam
Cyclosporine {u} (Compound) upregulates {v} (Gene) CXCL2
CXCL2 {u} (Gene) is associated with {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Fenoldopam
Cyclosporine {u} (Compound) binds {v} (Gene) CYP3A5
CYP3A5 {u} (Gene) is associated with {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Fenoldopam
Cyclosporine {u} (Compound) upregulates {v} (Gene) CXCL2
CXCL2 {u} (Gene) is upregulated by {v} (Compound) Treprostinil
Treprostinil {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fenoldopam
Cyclosporine {u} (Compound) binds {v} (Gene) CYP3A5
CYP3A5 {u} (Gene) is bound by {v} (Compound) Dexamethasone
Dexamethasone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fenoldopam
Cyclosporine (Compound) causes Creatinine increased (Side Effect) and Creatinine increased (Side Effect) is caused by Fenoldopam (Compound)
Cyclosporine (Compound) causes Haemorrhage (Side Effect) and Haemorrhage (Side Effect) is caused by Dexamethasone (Compound) and Dexamethasone may cause a moderate interaction that could exacerbate diseases when taken with Fenoldopam
Cyclosporine (Compound) causes Vomiting (Side Effect) and Vomiting (Side Effect) is caused by Phentolamine (Compound) and Phentolamine may cause a moderate interaction that could exacerbate diseases when taken with Fenoldopam
Cyclosporine (Compound) treats focal segmental glomerulosclerosis (Disease) and focal segmental glomerulosclerosis (Disease) resembles hypertension (Disease) and hypertension (Disease) is treated by Fenoldopam (Compound)
Cyclosporine (Compound) downregulates BIRC5 (Gene) and BIRC5 (Gene) is associated with hypertension (Disease) and hypertension (Disease) is treated by Fenoldopam (Compound)
Cyclosporine (Compound) treats focal segmental glomerulosclerosis (Disease) and focal segmental glomerulosclerosis (Disease) is associated with SPP1 (Gene) and SPP1 (Gene) is upregulated by Fenoldopam (Compound)
Cyclosporine (Compound) upregulates CXCL2 (Gene) and CXCL2 (Gene) is associated with hypertension (Disease) and hypertension (Disease) is treated by Fenoldopam (Compound)
Cyclosporine (Compound) binds CYP3A5 (Gene) and CYP3A5 (Gene) is associated with hypertension (Disease) and hypertension (Disease) is treated by Fenoldopam (Compound)
Cyclosporine (Compound) upregulates CXCL2 (Gene) and CXCL2 (Gene) is upregulated by Treprostinil (Compound) and Treprostinil may cause a moderate interaction that could exacerbate diseases when taken with Fenoldopam
Cyclosporine (Compound) binds CYP3A5 (Gene) and CYP3A5 (Gene) is bound by Dexamethasone (Compound) and Dexamethasone may cause a moderate interaction that could exacerbate diseases when taken with Fenoldopam