DDInter1458 DDInter690
Phenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist and norepinephrine reuptake inhibitor. It has been used as a decongestant and appetite suppressant. Currently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic strokes.
A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.
Phenylpropanolamine {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Ethanol
Phenylpropanolamine {u} may lead to a major life threatening interaction when taken with {v} Fluvoxamine
Fluvoxamine {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Ethanol
Phenylpropanolamine {u} (Compound) resembles {v} (Compound) Benzyl alcohol
Benzyl alcohol {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Ethanol
Phenylpropanolamine {u} may lead to a major life threatening interaction when taken with {v} Fluoxetine
Fluoxetine {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Ethanol
Phenylpropanolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Perphenazine
Perphenazine {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Ethanol
Phenylpropanolamine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Colchicine
Colchicine {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Ethanol
Phenylpropanolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amitriptyline
Amitriptyline {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Ethanol
Phenylpropanolamine {u} (Compound) resembles {v} (Compound) and {u} may lead to a major life threatening interaction when taken with {v} Phenelzine
Phenelzine {u} (Compound) binds {v} (Gene) CYP2C19
CYP2C19 {u} (Gene) is bound by {v} (Compound) Ethanol
Phenylpropanolamine {u} (Compound) treats {v} (Disease) obesity
obesity {u} (Disease) is associated with {v} (Gene) ADH1B
ADH1B {u} (Gene) is bound by {v} (Compound) Ethanol
Phenylpropanolamine {u} (Compound) downregulates {v} (Gene) PLOD3
PLOD3 {u} (Gene) is regulated by {v} (Gene) CYP1A1
CYP1A1 {u} (Gene) is bound by {v} (Compound) Ethanol
Phenylpropanolamine (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Ethanol (Compound)
Phenylpropanolamine may lead to a major life threatening interaction when taken with Fluvoxamine and Fluvoxamine (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Ethanol (Compound)
Phenylpropanolamine (Compound) resembles Benzyl alcohol (Compound) and Benzyl alcohol (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Ethanol (Compound)
Phenylpropanolamine may lead to a major life threatening interaction when taken with Fluoxetine and Fluoxetine (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Ethanol (Compound)
Phenylpropanolamine may cause a moderate interaction that could exacerbate diseases when taken with Perphenazine and Perphenazine (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Ethanol (Compound)
Phenylpropanolamine may cause a minor interaction that can limit clinical effects when taken with Colchicine and Colchicine (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Ethanol (Compound)
Phenylpropanolamine may cause a moderate interaction that could exacerbate diseases when taken with Amitriptyline and Amitriptyline (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Ethanol (Compound)
Phenylpropanolamine (Compound) resembles Phenelzine (Compound) and Phenylpropanolamine may lead to a major life threatening interaction when taken with Phenelzine and Phenelzine (Compound) binds CYP2C19 (Gene) and CYP2C19 (Gene) is bound by Ethanol (Compound)
Phenylpropanolamine (Compound) treats obesity (Disease) and obesity (Disease) is associated with ADH1B (Gene) and ADH1B (Gene) is bound by Ethanol (Compound)
Phenylpropanolamine (Compound) downregulates PLOD3 (Gene) and PLOD3 (Gene) is regulated by CYP1A1 (Gene) and CYP1A1 (Gene) is bound by Ethanol (Compound)