DDInter48 DDInter83
Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints. This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals. Allopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and is frequently used in the treatment of chronic gout. It was initially approved by the FDA in 1966 and is now formulated by several manufacturers.
Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum concentrations than ampicillin. Amoxicillin was granted FDA approval on 18 January 1974.
Allopurinol {u} (Compound) causes {v} (Side Effect) Pruritus
Pruritus {u} (Side Effect) is caused by {v} (Compound) Amoxicillin
Allopurinol {u} (Compound) causes {v} (Side Effect) Pruritus
Pruritus {u} (Side Effect) is caused by {v} (Compound) Nafcillin
Nafcillin {u} (Compound) resembles {v} (Compound) Amoxicillin
Allopurinol {u} (Compound) causes {v} (Side Effect) Flatulence
Flatulence {u} (Side Effect) is caused by {v} (Compound) Carbenicillin
Carbenicillin {u} (Compound) resembles {v} (Compound) Amoxicillin
Allopurinol {u} (Compound) causes {v} (Side Effect) Infection
Infection {u} (Side Effect) is caused by {v} (Compound) Clarithromycin
Clarithromycin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Amoxicillin
Allopurinol {u} (Compound) causes {v} (Side Effect) Epilepsy
Epilepsy {u} (Side Effect) is caused by {v} (Compound) Estradiol
Estradiol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amoxicillin
Allopurinol {u} (Compound) causes {v} (Side Effect) Coma
Coma {u} (Side Effect) is caused by {v} (Compound) Amiloride
Amiloride {u} may cause a minor interaction that can limit clinical effects when taken with {v} Amoxicillin
Allopurinol {u} (Compound) causes {v} (Side Effect) Allergic cutaneous angiitis
Allergic cutaneous angiitis {u} (Side Effect) is caused by {v} (Compound) Methotrexate
Methotrexate {u} may lead to a major life threatening interaction when taken with {v} Amoxicillin
Allopurinol {u} (Compound) binds {v} (Gene) SLC22A8
SLC22A8 {u} (Gene) is bound by {v} (Compound) Cephalexin
Cephalexin {u} (Compound) resembles {v} (Compound) Amoxicillin
Allopurinol {u} (Compound) binds {v} (Gene) SLC22A8
SLC22A8 {u} (Gene) is bound by {v} (Compound) Cefadroxil
Cefadroxil {u} (Compound) resembles {v} (Compound) Amoxicillin
Allopurinol {u} (Compound) binds {v} (Gene) SLC22A8
SLC22A8 {u} (Gene) is bound by {v} (Compound) Probenecid
Probenecid {u} may cause a minor interaction that can limit clinical effects when taken with {v} Amoxicillin
Allopurinol (Compound) causes Pruritus (Side Effect) and Pruritus (Side Effect) is caused by Amoxicillin (Compound)
Allopurinol (Compound) causes Pruritus (Side Effect) and Pruritus (Side Effect) is caused by Nafcillin (Compound) and Nafcillin (Compound) resembles Amoxicillin (Compound)
Allopurinol (Compound) causes Flatulence (Side Effect) and Flatulence (Side Effect) is caused by Carbenicillin (Compound) and Carbenicillin (Compound) resembles Amoxicillin (Compound)
Allopurinol (Compound) causes Infection (Side Effect) and Infection (Side Effect) is caused by Clarithromycin (Compound) and Clarithromycin may cause a minor interaction that can limit clinical effects when taken with Amoxicillin
Allopurinol (Compound) causes Epilepsy (Side Effect) and Epilepsy (Side Effect) is caused by Estradiol (Compound) and Estradiol may cause a moderate interaction that could exacerbate diseases when taken with Amoxicillin
Allopurinol (Compound) causes Coma (Side Effect) and Coma (Side Effect) is caused by Amiloride (Compound) and Amiloride may cause a minor interaction that can limit clinical effects when taken with Amoxicillin
Allopurinol (Compound) causes Allergic cutaneous angiitis (Side Effect) and Allergic cutaneous angiitis (Side Effect) is caused by Methotrexate (Compound) and Methotrexate may lead to a major life threatening interaction when taken with Amoxicillin
Allopurinol (Compound) binds SLC22A8 (Gene) and SLC22A8 (Gene) is bound by Cephalexin (Compound) and Cephalexin (Compound) resembles Amoxicillin (Compound)
Allopurinol (Compound) binds SLC22A8 (Gene) and SLC22A8 (Gene) is bound by Cefadroxil (Compound) and Cefadroxil (Compound) resembles Amoxicillin (Compound)
Allopurinol (Compound) binds SLC22A8 (Gene) and SLC22A8 (Gene) is bound by Probenecid (Compound) and Probenecid may cause a minor interaction that can limit clinical effects when taken with Amoxicillin