DDInter1870 DDInter1180
Trihexyphenidyl is a centrally acting muscarinic antagonist used for treatment of parkinsonism and drug-induced extrapyramidal disorders.[L31773,L31778] Its discovery was published in 1949 in a study looking for drugs with antispasmodic activity. Trihexyphenidyl is rarely used in the treatment of parkinsonism, and is not a first line treatment due to significant adverse effects. It has largely been replaced by drugs such as [levodopa]. Trihexyphenidyl was granted FDA approval on 13 May 1949.
Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Trihexyphenidyl {u} (Compound) resembles {v} (Compound) Diphenidol
Trihexyphenidyl {u} (Compound) resembles {v} (Compound) Biperiden
Trihexyphenidyl {u} (Compound) binds {v} (Gene) CHRM1
Trihexyphenidyl {u} (Compound) palliates {v} (Disease) Parkinson's disease
Trihexyphenidyl {u} (Compound) causes {v} (Side Effect) Nervousness
Trihexyphenidyl {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eluxadoline
Trihexyphenidyl {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Morphine
Trihexyphenidyl {u} may lead to a major life threatening interaction when taken with {v} Potassium chloride
Trihexyphenidyl {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Glycopyrronium
Trihexyphenidyl (Compound) resembles Diphenidol (Compound)
Trihexyphenidyl (Compound) resembles Biperiden (Compound)
Trihexyphenidyl (Compound) binds CHRM1 (Gene)
Trihexyphenidyl (Compound) palliates Parkinson's disease (Disease)
Trihexyphenidyl (Compound) causes Nervousness (Side Effect)
Trihexyphenidyl may cause a moderate interaction that could exacerbate diseases when taken with Eluxadoline
Trihexyphenidyl may cause a moderate interaction that could exacerbate diseases when taken with Morphine
Trihexyphenidyl may lead to a major life threatening interaction when taken with Potassium chloride
Trihexyphenidyl (Compound) resembles Glycopyrronium (Compound) and Trihexyphenidyl may cause a moderate interaction that could exacerbate diseases when taken with Glycopyrronium