DDInter593 DDInter1798
Doxepin is a psychotropic agent with antidepressant and anxiolytic properties. It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to [cidoxepin]. Doxepin commonly produces a 5:1 (E):(Z) racemic mixture. In a strict sense, doxepin is not a tricyclic antidepressant but it is commonly associated with the class since it shares a lot of properties with members of the drug family including [amitriptyline], [clomipramine], [desipramine], [imipramine], [nortriptyline], [protriptyline] and [trimipramine]. Doxepin was developed by Pfizer and FDA approved in 1969 as an antidepressant. However, in 2010 it was approved for the treatment of insomnia. The latter
A thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics.
Doxepin {u} (Compound) resembles {v} (Compound) Thiothixene
Doxepin {u} (Compound) resembles {v} (Compound) Olopatadine
Olopatadine {u} (Compound) resembles {v} (Compound) Thiothixene
Doxepin {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amitriptyline
Amitriptyline {u} (Compound) resembles {v} (Compound) Thiothixene
Doxepin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Chlorpromazine
Chlorpromazine {u} (Compound) resembles {v} (Compound) Thiothixene
Doxepin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Quetiapine
Quetiapine {u} (Compound) resembles {v} (Compound) Thiothixene
Doxepin {u} may lead to a major life threatening interaction when taken with {v} Thioridazine
Thioridazine {u} (Compound) resembles {v} (Compound) Thiothixene
Doxepin {u} (Compound) binds {v} (Gene) HRH1
HRH1 {u} (Gene) is bound by {v} (Compound) Thiothixene
Doxepin {u} (Compound) upregulates {v} (Gene) MCOLN1
MCOLN1 {u} (Gene) is upregulated by {v} (Compound) Thiothixene
Doxepin {u} (Compound) causes {v} (Side Effect) Cough
Cough {u} (Side Effect) is caused by {v} (Compound) Thiothixene
Doxepin {u} (Compound) resembles {v} (Compound) Olopatadine
Olopatadine {u} (Compound) resembles {v} (Compound) Acepromazine
Acepromazine {u} (Compound) resembles {v} (Compound) Thiothixene
Doxepin (Compound) resembles Thiothixene (Compound)
Doxepin (Compound) resembles Olopatadine (Compound) and Olopatadine (Compound) resembles Thiothixene (Compound)
Doxepin (Compound) resembles Amitriptyline (Compound) and Doxepin may cause a moderate interaction that could exacerbate diseases when taken with Amitriptyline and Amitriptyline (Compound) resembles Thiothixene (Compound)
Doxepin may cause a moderate interaction that could exacerbate diseases when taken with Chlorpromazine and Chlorpromazine (Compound) resembles Thiothixene (Compound)
Doxepin may cause a moderate interaction that could exacerbate diseases when taken with Quetiapine and Quetiapine (Compound) resembles Thiothixene (Compound)
Doxepin may lead to a major life threatening interaction when taken with Thioridazine and Thioridazine (Compound) resembles Thiothixene (Compound)
Doxepin (Compound) binds HRH1 (Gene) and HRH1 (Gene) is bound by Thiothixene (Compound)
Doxepin (Compound) upregulates MCOLN1 (Gene) and MCOLN1 (Gene) is upregulated by Thiothixene (Compound)
Doxepin (Compound) causes Cough (Side Effect) and Cough (Side Effect) is caused by Thiothixene (Compound)
Doxepin (Compound) resembles Olopatadine (Compound) and Olopatadine (Compound) resembles Acepromazine (Compound) and Acepromazine (Compound) resembles Thiothixene (Compound)