DDInter458 DDInter1366
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus _Beauveria nivea_. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.
Cyclosporine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Oxycodone
Cyclosporine {u} (Compound) causes {v} (Side Effect) Gingivitis
Gingivitis {u} (Side Effect) is caused by {v} (Compound) Oxycodone
Cyclosporine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Hydromorphone
Hydromorphone {u} (Compound) resembles {v} (Compound) Oxycodone
Cyclosporine {u} (Compound) causes {v} (Side Effect) Gingivitis
Gingivitis {u} (Side Effect) is caused by {v} (Compound) Bexarotene
Bexarotene {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxycodone
Cyclosporine {u} (Compound) causes {v} (Side Effect) Mental disability
Mental disability {u} (Side Effect) is caused by {v} (Compound) Naltrexone
Naltrexone {u} may lead to a major life threatening interaction when taken with {v} Oxycodone
Cyclosporine {u} (Compound) causes {v} (Side Effect) Hyperhidrosis
Hyperhidrosis {u} (Side Effect) is caused by {v} (Compound) Hydromorphone
Hydromorphone {u} (Compound) resembles {v} (Compound) Oxycodone
Cyclosporine {u} (Compound) causes {v} (Side Effect) Abnormal vision
Abnormal vision {u} (Side Effect) is caused by {v} (Compound) Dolasetron
Dolasetron {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxycodone
Cyclosporine {u} (Compound) binds {v} (Gene) CYP3A5
CYP3A5 {u} (Gene) is bound by {v} (Compound) Clopidogrel
Clopidogrel {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxycodone
Cyclosporine {u} (Compound) causes {v} (Side Effect) Mental disability
Mental disability {u} (Side Effect) is caused by {v} (Compound) Oxymorphone
Oxymorphone {u} (Compound) resembles {v} (Compound) Oxycodone
Cyclosporine {u} (Compound) causes {v} (Side Effect) Glossitis
Glossitis {u} (Side Effect) is caused by {v} (Compound) Chloramphenicol
Chloramphenicol {u} may lead to a major life threatening interaction when taken with {v} Oxycodone
Cyclosporine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Oxycodone (Compound)
Cyclosporine (Compound) causes Gingivitis (Side Effect) and Gingivitis (Side Effect) is caused by Oxycodone (Compound)
Cyclosporine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Hydromorphone (Compound) and Hydromorphone (Compound) resembles Oxycodone (Compound)
Cyclosporine (Compound) causes Gingivitis (Side Effect) and Gingivitis (Side Effect) is caused by Bexarotene (Compound) and Bexarotene may cause a moderate interaction that could exacerbate diseases when taken with Oxycodone
Cyclosporine (Compound) causes Mental disability (Side Effect) and Mental disability (Side Effect) is caused by Naltrexone (Compound) and Naltrexone may lead to a major life threatening interaction when taken with Oxycodone
Cyclosporine (Compound) causes Hyperhidrosis (Side Effect) and Hyperhidrosis (Side Effect) is caused by Hydromorphone (Compound) and Hydromorphone (Compound) resembles Oxycodone (Compound)
Cyclosporine (Compound) causes Abnormal vision (Side Effect) and Abnormal vision (Side Effect) is caused by Dolasetron (Compound) and Dolasetron may cause a moderate interaction that could exacerbate diseases when taken with Oxycodone
Cyclosporine (Compound) binds CYP3A5 (Gene) and CYP3A5 (Gene) is bound by Clopidogrel (Compound) and Clopidogrel may cause a moderate interaction that could exacerbate diseases when taken with Oxycodone
Cyclosporine (Compound) causes Mental disability (Side Effect) and Mental disability (Side Effect) is caused by Oxymorphone (Compound) and Oxymorphone (Compound) resembles Oxycodone (Compound)
Cyclosporine (Compound) causes Glossitis (Side Effect) and Glossitis (Side Effect) is caused by Chloramphenicol (Compound) and Chloramphenicol may lead to a major life threatening interaction when taken with Oxycodone