DDInter363 DDInter1676
The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
Siponimod, also known as _Mayzent_, by Novartis, is a new drug formulated for the management of Multiple Sclerosis (MS). It was approved by the FDA on March 26, 2019 and by Health Canada on February 20, 2020. This drug is considered a _sphingosine-1-phosphate (S1P) receptor modulator_ and is thought to play a role in suppressing the central nervous system inflammation that is associated with MS [FDA label]. Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system that is chronic and inflammatory, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of life. Symptoms may include but are not limited to fatigue, gait changes, bowel or bladder dysfunction, abnormal muscle twitching, vision disturbance, and depressing or mood swings. MS is one of the most common causes of neurological disability in young adults and is found to occur more frequently in women than in men.[A176474,L5792]
Chlorpromazine {u} (Compound) resembles {v} (Compound) Prochlorperazine
Chlorpromazine {u} (Compound) resembles {v} (Compound) Ethopropazine
Chlorpromazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Carbinoxamine
Chlorpromazine {u} (Compound) binds {v} (Gene) HTR2C
Chlorpromazine {u} (Compound) upregulates {v} (Gene) AARS
Chlorpromazine {u} (Compound) palliates {v} (Disease) bipolar disorder
Chlorpromazine {u} (Compound) is included by {v} (Pharmacologic Class) Phenothiazines
Chlorpromazine {u} (Compound) downregulates {v} (Gene) EED
Chlorpromazine {u} (Compound) causes {v} (Side Effect) Convulsion
Chlorpromazine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium oxide
Chlorpromazine (Compound) resembles Prochlorperazine (Compound)
Chlorpromazine (Compound) resembles Ethopropazine (Compound)
Chlorpromazine may cause a moderate interaction that could exacerbate diseases when taken with Carbinoxamine
Chlorpromazine (Compound) binds HTR2C (Gene)
Chlorpromazine (Compound) upregulates AARS (Gene)
Chlorpromazine (Compound) palliates bipolar disorder (Disease)
Chlorpromazine (Compound) is included by Phenothiazines (Pharmacologic Class)
Chlorpromazine (Compound) downregulates EED (Gene)
Chlorpromazine (Compound) causes Convulsion (Side Effect)
Chlorpromazine may cause a minor interaction that can limit clinical effects when taken with Magnesium oxide