DDInter367 DDInter1627
Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight. Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are considered the main forms of vitamin d and are found in various types of food for daily intake. Structurally, ergocalciferol differs from cholecalciferol in that it possesses a double bond between C22 and C23 and has an additional methyl group at C24. Finally, ergocalciferol is pharmacologically less potent than cholecalciferol, which makes vitamin D3 the preferred agent for medical use. Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus levels in a
Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. Clinical trials suggest its efficacy in the treatment of partial seizures.
Cholecalciferol {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Rufinamide
Cholecalciferol {u} (Compound) resembles {v} (Compound) Calcitriol
Calcitriol {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Rufinamide
Cholecalciferol {u} may lead to a major life threatening interaction when taken with {v} Paricalcitol
Paricalcitol {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Rufinamide
Cholecalciferol {u} (Compound) resembles {v} (Compound) Calcitriol
Calcitriol {u} (Compound) upregulates {v} (Gene) CES1
CES1 {u} (Gene) is bound by {v} (Compound) Rufinamide
Cholecalciferol {u} (Compound) resembles {v} (Compound) Calcipotriol
Calcipotriol {u} (Compound) causes {v} (Side Effect) Rash
Rash {u} (Side Effect) is caused by {v} (Compound) Rufinamide
Cholecalciferol {u} may lead to a major life threatening interaction when taken with {v} Paricalcitol
Paricalcitol {u} (Compound) causes {v} (Side Effect) Mental disorder
Mental disorder {u} (Side Effect) is caused by {v} (Compound) Rufinamide
Cholecalciferol {u} (Compound) treats {v} (Disease) ulcerative colitis
ulcerative colitis {u} (Disease) is associated with {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Rufinamide
Cholecalciferol {u} (Compound) binds {v} (Gene) CYP11A1
CYP11A1 {u} (Gene) is associated with {v} (Disease) epilepsy syndrome
epilepsy syndrome {u} (Disease) is treated by {v} (Compound) Rufinamide
Cholecalciferol {u} (Compound) palliates {v} (Disease) chronic kidney failure
chronic kidney failure {u} (Disease) is associated with {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Rufinamide
Cholecalciferol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Orlistat
Orlistat {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Rufinamide
Cholecalciferol (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Rufinamide (Compound)
Cholecalciferol (Compound) resembles Calcitriol (Compound) and Calcitriol (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Rufinamide (Compound)
Cholecalciferol may lead to a major life threatening interaction when taken with Paricalcitol and Paricalcitol (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Rufinamide (Compound)
Cholecalciferol (Compound) resembles Calcitriol (Compound) and Calcitriol (Compound) upregulates CES1 (Gene) and CES1 (Gene) is bound by Rufinamide (Compound)
Cholecalciferol (Compound) resembles Calcipotriol (Compound) and Calcipotriol (Compound) causes Rash (Side Effect) and Rash (Side Effect) is caused by Rufinamide (Compound)
Cholecalciferol may lead to a major life threatening interaction when taken with Paricalcitol and Paricalcitol (Compound) causes Mental disorder (Side Effect) and Mental disorder (Side Effect) is caused by Rufinamide (Compound)
Cholecalciferol (Compound) treats ulcerative colitis (Disease) and ulcerative colitis (Disease) is associated with ALB (Gene) and ALB (Gene) is bound by Rufinamide (Compound)
Cholecalciferol (Compound) binds CYP11A1 (Gene) and CYP11A1 (Gene) is associated with epilepsy syndrome (Disease) and epilepsy syndrome (Disease) is treated by Rufinamide (Compound)
Cholecalciferol (Compound) palliates chronic kidney failure (Disease) and chronic kidney failure (Disease) is associated with ALB (Gene) and ALB (Gene) is bound by Rufinamide (Compound)
Cholecalciferol may cause a minor interaction that can limit clinical effects when taken with Orlistat and Orlistat (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Rufinamide (Compound)