DDInter1783 DDInter832
Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the bacterial 50S ribosomal subunit and may alter the cytoplasmic membrane causing intracellular components to leak from bacterial cells. The FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml. Other formulations of tetracycline continue to be used.
A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Tetracycline {u} (Compound) resembles {v} (Compound) Demeclocycline
Tetracycline {u} (Compound) binds {v} (Gene) ALB
Tetracycline {u} (Compound) is included by {v} (Pharmacologic Class) Tetracyclines
Tetracycline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Diclofenamide
Tetracycline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Triamterene
Tetracycline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Magnesium carbonate
Tetracycline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Digoxin
Tetracycline {u} may lead to a major life threatening interaction when taken with {v} Methoxyflurane
Tetracycline {u} may lead to a major life threatening interaction when taken with {v} Acitretin
Tetracycline (Compound) resembles Demeclocycline (Compound)
Tetracycline (Compound) binds ALB (Gene)
Tetracycline (Compound) is included by Tetracyclines (Pharmacologic Class)
Tetracycline may cause a minor interaction that can limit clinical effects when taken with Diclofenamide
Tetracycline may cause a minor interaction that can limit clinical effects when taken with Triamterene
Tetracycline may cause a moderate interaction that could exacerbate diseases when taken with Magnesium carbonate
Tetracycline may cause a moderate interaction that could exacerbate diseases when taken with Digoxin
Tetracycline may lead to a major life threatening interaction when taken with Methoxyflurane
Tetracycline may lead to a major life threatening interaction when taken with Acitretin