DDInter1717 DDInter790
Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to dyspepsia. It is considered a _cytoprotective agent_, protecting cells in the gastrointestinal tract from damage caused by agents such as gastric acid, bile salts, alcohol, and acetylsalicylic acid (aspirin), among other substances [A177655, F4519]. Sucralfate has been shown to be a well-tolerated and safe drug. It is sold under many brands and is available in both tablet and suspension forms. It was approved by the FDA 1982 in tablet form, and in 1994 for the suspension form [L6073, L6076].
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of water from the body. Furosemide has a fast onset and short duration of action and has been used safely and effectively in both pediatric and adult patients. The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential. In addition to oral formulations, the solution for intravenous and intramuscular administration is also available, which is typically limited to patients who are unable to take oral medication or for patients in emergency clinical situations.
Sucralfate {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Furosemide
Sucralfate {u} (Compound) causes {v} (Side Effect) Hyponatraemia
Hyponatraemia {u} (Side Effect) is caused by {v} (Compound) Furosemide
Sucralfate {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is associated with {v} (Disease) coronary artery disease
coronary artery disease {u} (Disease) is treated by {v} (Compound) Furosemide
Sucralfate {u} (Compound) causes {v} (Side Effect) Hyponatraemia
Hyponatraemia {u} (Side Effect) is caused by {v} (Compound) Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Sucralfate {u} (Compound) binds {v} (Gene) FGG
FGG {u} (Gene) is regulated by {v} (Gene) CA12
CA12 {u} (Gene) is bound by {v} (Compound) Furosemide
Sucralfate {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is associated with {v} (Disease) chronic kidney failure
chronic kidney failure {u} (Disease) is palliated by {v} (Compound) Furosemide
Sucralfate {u} (Compound) binds {v} (Gene) FGA
FGA {u} (Gene) interacts with {v} (Gene) and {u} (Gene) is regulated by {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Furosemide
Sucralfate {u} may cause a minor interaction that can limit clinical effects when taken with {v} Sotalol
Sotalol {u} (Compound) causes {v} (Side Effect) Pain
Pain {u} (Side Effect) is caused by {v} (Compound) Furosemide
Sucralfate {u} may cause a minor interaction that can limit clinical effects when taken with {v} Acebutolol
Acebutolol {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Furosemide
Sucralfate {u} may cause a minor interaction that can limit clinical effects when taken with {v} Diclofenac
Diclofenac {u} (Compound) binds {v} (Gene) SLC22A8
SLC22A8 {u} (Gene) is bound by {v} (Compound) Furosemide
Sucralfate (Compound) binds ALB (Gene) and ALB (Gene) is bound by Furosemide (Compound)
Sucralfate (Compound) causes Hyponatraemia (Side Effect) and Hyponatraemia (Side Effect) is caused by Furosemide (Compound)
Sucralfate (Compound) binds ALB (Gene) and ALB (Gene) is associated with coronary artery disease (Disease) and coronary artery disease (Disease) is treated by Furosemide (Compound)
Sucralfate (Compound) causes Hyponatraemia (Side Effect) and Hyponatraemia (Side Effect) is caused by Indapamide (Compound) and Indapamide (Compound) resembles Furosemide (Compound)
Sucralfate (Compound) binds FGG (Gene) and FGG (Gene) is regulated by CA12 (Gene) and CA12 (Gene) is bound by Furosemide (Compound)
Sucralfate (Compound) binds ALB (Gene) and ALB (Gene) is associated with chronic kidney failure (Disease) and chronic kidney failure (Disease) is palliated by Furosemide (Compound)
Sucralfate (Compound) binds FGA (Gene) and FGA (Gene) interacts with ALB (Gene) and FGA (Gene) is regulated by ALB (Gene) and ALB (Gene) is bound by Furosemide (Compound)
Sucralfate may cause a minor interaction that can limit clinical effects when taken with Sotalol and Sotalol (Compound) causes Pain (Side Effect) and Pain (Side Effect) is caused by Furosemide (Compound)
Sucralfate may cause a minor interaction that can limit clinical effects when taken with Acebutolol and Acebutolol (Compound) treats hypertension (Disease) and hypertension (Disease) is treated by Furosemide (Compound)
Sucralfate may cause a minor interaction that can limit clinical effects when taken with Diclofenac and Diclofenac (Compound) binds SLC22A8 (Gene) and SLC22A8 (Gene) is bound by Furosemide (Compound)