DDInter1642 DDInter57
Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.
An alkylating agent proposed as an antineoplastic. It also acts as a chemosterilant for male houseflies and other insects.
Altretamine {u} (Compound) treats {v} (Disease) ovarian cancer
Altretamine {u} (Compound) upregulates {v} (Gene) ST6GALNAC2
Altretamine {u} (Compound) is included by {v} (Pharmacologic Class) Alkylating Activity
Altretamine {u} (Compound) downregulates {v} (Gene) KRT7
Altretamine {u} (Compound) causes {v} (Side Effect) Leukopenia
Altretamine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Delafloxacin
Altretamine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Moxifloxacin
Altretamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Zidovudine
Altretamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Palifermin
Altretamine {u} may lead to a major life threatening interaction when taken with {v} Samarium (153Sm) lexidronam
Altretamine (Compound) treats ovarian cancer (Disease)
Altretamine (Compound) upregulates ST6GALNAC2 (Gene)
Altretamine (Compound) is included by Alkylating Activity (Pharmacologic Class)
Altretamine (Compound) downregulates KRT7 (Gene)
Altretamine (Compound) causes Leukopenia (Side Effect)
Altretamine may cause a minor interaction that can limit clinical effects when taken with Delafloxacin
Altretamine may cause a minor interaction that can limit clinical effects when taken with Moxifloxacin
Altretamine may cause a moderate interaction that could exacerbate diseases when taken with Zidovudine
Altretamine may cause a moderate interaction that could exacerbate diseases when taken with Palifermin
Altretamine may lead to a major life threatening interaction when taken with Samarium (153Sm) lexidronam