DDInter305 DDInter1180
Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker.[L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension.[L7889,L7892] The dual action of carvedilol is advantageous in combination therapies as moderate doses of 2 drugs have a decreased incidence of adverse effects compared to high dose monotherapy in the treatment of moderate hypertension. Carvedilol was granted FDA approval on 14 September 1995.
Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Carvedilol {u} (Compound) resembles {v} (Compound) Propafenone
Carvedilol {u} (Compound) resembles {v} (Compound) Bopindolol
Carvedilol {u} (Compound) treats {v} (Disease) hypertension
Carvedilol {u} (Compound) binds {v} (Gene) CYP1A1
Carvedilol {u} (Compound) upregulates {v} (Gene) INSIG1
Carvedilol {u} (Compound) is included by {v} (Pharmacologic Class) Adrenergic beta1-Antagonists
Carvedilol {u} (Compound) downregulates {v} (Gene) CDC20
Carvedilol {u} (Compound) causes {v} (Side Effect) Angina unstable
Carvedilol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Kaolin
Carvedilol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Levothyroxine
Carvedilol (Compound) resembles Propafenone (Compound)
Carvedilol (Compound) resembles Bopindolol (Compound)
Carvedilol (Compound) treats hypertension (Disease)
Carvedilol (Compound) binds CYP1A1 (Gene)
Carvedilol (Compound) upregulates INSIG1 (Gene)
Carvedilol (Compound) is included by Adrenergic beta1-Antagonists (Pharmacologic Class)
Carvedilol (Compound) downregulates CDC20 (Gene)
Carvedilol (Compound) causes Angina unstable (Side Effect)
Carvedilol may cause a minor interaction that can limit clinical effects when taken with Kaolin
Carvedilol may cause a minor interaction that can limit clinical effects when taken with Levothyroxine