DDInter605 DDInter1139
Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond. Drotrecogin alfa was withdrawn from the market after a major study indicated that it was not effective in improving outcomes in patients with sepsis.
A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Drotrecogin alfa {u} may lead to a major life threatening interaction when taken with {v} Ketoprofen
Ketoprofen {u} (Compound) resembles {v} (Compound) Mefenamic acid
Drotrecogin alfa {u} may lead to a major life threatening interaction when taken with {v} Acetylsalicylic acid
Acetylsalicylic acid {u} (Compound) resembles {v} (Compound) Mefenamic acid
Drotrecogin alfa {u} may lead to a major life threatening interaction when taken with {v} Ketoprofen
Ketoprofen {u} (Compound) resembles {v} (Compound) Oxybenzone
Oxybenzone {u} (Compound) resembles {v} (Compound) Mefenamic acid
Drotrecogin alfa {u} may lead to a major life threatening interaction when taken with {v} Flurbiprofen
Flurbiprofen {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ketoprofen
Ketoprofen {u} (Compound) resembles {v} (Compound) Mefenamic acid
Drotrecogin alfa {u} may lead to a major life threatening interaction when taken with {v} Meclofenamic acid
Meclofenamic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Flurbiprofen
Flurbiprofen {u} (Compound) resembles {v} (Compound) Mefenamic acid
Drotrecogin alfa {u} may cause a minor interaction that can limit clinical effects when taken with {v} Capsicum
Capsicum {u} may cause a minor interaction that can limit clinical effects when taken with {v} Acetylsalicylic acid
Acetylsalicylic acid {u} (Compound) resembles {v} (Compound) Mefenamic acid
Drotrecogin alfa {u} may lead to a major life threatening interaction when taken with {v} Ketoprofen
Ketoprofen {u} (Compound) resembles {v} (Compound) Nepafenac
Nepafenac {u} (Compound) resembles {v} (Compound) Mefenamic acid
Drotrecogin alfa {u} may lead to a major life threatening interaction when taken with {v} Meclofenamic acid
Meclofenamic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acetylsalicylic acid
Acetylsalicylic acid {u} (Compound) resembles {v} (Compound) Mefenamic acid
Drotrecogin alfa {u} may lead to a major life threatening interaction when taken with {v} Acetylsalicylic acid
Acetylsalicylic acid {u} (Compound) resembles {v} (Compound) Salsalate
Salsalate {u} (Compound) resembles {v} (Compound) Mefenamic acid
Drotrecogin alfa {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Escitalopram
Escitalopram {u} (Compound) causes {v} (Side Effect) Haemoglobin
Haemoglobin {u} (Side Effect) is caused by {v} (Compound) Mefenamic acid
Drotrecogin alfa may lead to a major life threatening interaction when taken with Ketoprofen and Ketoprofen (Compound) resembles Mefenamic acid (Compound)
Drotrecogin alfa may lead to a major life threatening interaction when taken with Acetylsalicylic acid and Acetylsalicylic acid (Compound) resembles Mefenamic acid (Compound)
Drotrecogin alfa may lead to a major life threatening interaction when taken with Ketoprofen and Ketoprofen (Compound) resembles Oxybenzone (Compound) and Oxybenzone (Compound) resembles Mefenamic acid (Compound)
Drotrecogin alfa may lead to a major life threatening interaction when taken with Flurbiprofen and Flurbiprofen may cause a moderate interaction that could exacerbate diseases when taken with Ketoprofen and Ketoprofen (Compound) resembles Mefenamic acid (Compound)
Drotrecogin alfa may lead to a major life threatening interaction when taken with Meclofenamic acid and Meclofenamic acid may cause a moderate interaction that could exacerbate diseases when taken with Flurbiprofen and Flurbiprofen (Compound) resembles Mefenamic acid (Compound)
Drotrecogin alfa may cause a minor interaction that can limit clinical effects when taken with Capsicum and Capsicum may cause a minor interaction that can limit clinical effects when taken with Acetylsalicylic acid and Acetylsalicylic acid (Compound) resembles Mefenamic acid (Compound)
Drotrecogin alfa may lead to a major life threatening interaction when taken with Ketoprofen and Ketoprofen (Compound) resembles Nepafenac (Compound) and Nepafenac (Compound) resembles Mefenamic acid (Compound)
Drotrecogin alfa may lead to a major life threatening interaction when taken with Meclofenamic acid and Meclofenamic acid may cause a moderate interaction that could exacerbate diseases when taken with Acetylsalicylic acid and Acetylsalicylic acid (Compound) resembles Mefenamic acid (Compound)
Drotrecogin alfa may lead to a major life threatening interaction when taken with Acetylsalicylic acid and Acetylsalicylic acid (Compound) resembles Salsalate (Compound) and Salsalate (Compound) resembles Mefenamic acid (Compound)
Drotrecogin alfa may cause a moderate interaction that could exacerbate diseases when taken with Escitalopram and Escitalopram (Compound) causes Haemoglobin (Side Effect) and Haemoglobin (Side Effect) is caused by Mefenamic acid (Compound)