DDInter839 DDInter1016
Goserelin is a synthetic hormone. In men, it stops the production of the hormone testosterone, which may stimulate the growth of cancer cells. In women, goserelin decreases the production of the hormone estradiol (which may stimulate the growth of cancer cells) to levels similar to a postmenopausal state. When the medication is stopped, hormone levels return to normal.
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose]. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. [sucrose]). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in patients with cirrhosis.[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.
Goserelin {u} (Compound) resembles {v} (Compound) Pentagastrin
Goserelin {u} (Compound) resembles {v} (Compound) Cetrorelix
Goserelin {u} (Compound) treats {v} (Disease) breast cancer
Goserelin {u} (Compound) binds {v} (Gene) LHCGR
Goserelin {u} (Compound) upregulates {v} (Gene) SPAG4
Goserelin {u} (Compound) is included by {v} (Pharmacologic Class) Gonadotropin Releasing Hormone Receptor Agonists
Goserelin {u} (Compound) causes {v} (Side Effect) Reaction aggravation
Goserelin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Sulfamethoxazole
Goserelin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Troglitazone
Goserelin {u} may lead to a major life threatening interaction when taken with {v} Dolasetron
Goserelin (Compound) resembles Pentagastrin (Compound)
Goserelin (Compound) resembles Cetrorelix (Compound)
Goserelin (Compound) treats breast cancer (Disease)
Goserelin (Compound) binds LHCGR (Gene)
Goserelin (Compound) upregulates SPAG4 (Gene)
Goserelin (Compound) is included by Gonadotropin Releasing Hormone Receptor Agonists (Pharmacologic Class)
Goserelin (Compound) causes Reaction aggravation (Side Effect)
Goserelin may cause a minor interaction that can limit clinical effects when taken with Sulfamethoxazole
Goserelin may cause a moderate interaction that could exacerbate diseases when taken with Troglitazone
Goserelin may lead to a major life threatening interaction when taken with Dolasetron