DDInter698 DDInter273
Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid]. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and [risedronic acid]. Etidronic acid was granted FDA approval on 1 September 1977.
Calcium citrate is a salt typically used as a source of calcium in a variety of over the counter supplements.
Etidronic acid {u} (Compound) resembles {v} (Compound) Alendronic acid
Alendronic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Calcium citrate
Etidronic acid {u} (Compound) resembles {v} (Compound) Alendronic acid
Alendronic acid {u} (Compound) resembles {v} (Compound) Ibandronate
Ibandronate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Calcium citrate
Etidronic acid {u} (Compound) resembles {v} (Compound) Ibandronate
Ibandronate {u} (Compound) resembles {v} (Compound) Alendronic acid
Alendronic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Calcium citrate
Etidronic acid {u} (Compound) causes {v} (Side Effect) Headache
Headache {u} (Side Effect) is caused by {v} (Compound) Acebutolol
Acebutolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Calcium citrate
Etidronic acid {u} (Compound) resembles {v} (Compound) Alendronic acid
Alendronic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Aluminum hydroxide
Aluminum hydroxide {u} may lead to a major life threatening interaction when taken with {v} Calcium citrate
Etidronic acid {u} (Compound) resembles {v} (Compound) Clodronate
Clodronate {u} (Compound) resembles {v} (Compound) Alendronic acid
Alendronic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Calcium citrate
Etidronic acid {u} (Compound) treats {v} (Disease) Paget's disease of bone
Paget's disease of bone {u} (Disease) is treated by {v} (Compound) Alendronic acid
Alendronic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Calcium citrate
Etidronic acid {u} (Compound) binds {v} (Gene) PTPRS
PTPRS {u} (Gene) is bound by {v} (Compound) Alendronic acid
Alendronic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Calcium citrate
Etidronic acid {u} (Compound) upregulates {v} (Gene) PLSCR1
PLSCR1 {u} (Gene) is upregulated by {v} (Compound) Nisoldipine
Nisoldipine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Calcium citrate
Etidronic acid {u} (Compound) upregulates {v} (Gene) XBP1
XBP1 {u} (Gene) is downregulated by {v} (Compound) Digitoxin
Digitoxin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Calcium citrate
Etidronic acid (Compound) resembles Alendronic acid (Compound) and Alendronic acid may cause a moderate interaction that could exacerbate diseases when taken with Calcium citrate
Etidronic acid (Compound) resembles Alendronic acid (Compound) and Alendronic acid (Compound) resembles Ibandronate (Compound) and Ibandronate may cause a moderate interaction that could exacerbate diseases when taken with Calcium citrate
Etidronic acid (Compound) resembles Ibandronate (Compound) and Ibandronate (Compound) resembles Alendronic acid (Compound) and Alendronic acid may cause a moderate interaction that could exacerbate diseases when taken with Calcium citrate
Etidronic acid (Compound) causes Headache (Side Effect) and Headache (Side Effect) is caused by Acebutolol (Compound) and Acebutolol may cause a moderate interaction that could exacerbate diseases when taken with Calcium citrate
Etidronic acid (Compound) resembles Alendronic acid (Compound) and Alendronic acid may cause a moderate interaction that could exacerbate diseases when taken with Aluminum hydroxide and Aluminum hydroxide may lead to a major life threatening interaction when taken with Calcium citrate
Etidronic acid (Compound) resembles Clodronate (Compound) and Clodronate (Compound) resembles Alendronic acid (Compound) and Alendronic acid may cause a moderate interaction that could exacerbate diseases when taken with Calcium citrate
Etidronic acid (Compound) treats Paget's disease of bone (Disease) and Paget's disease of bone (Disease) is treated by Alendronic acid (Compound) and Alendronic acid may cause a moderate interaction that could exacerbate diseases when taken with Calcium citrate
Etidronic acid (Compound) binds PTPRS (Gene) and PTPRS (Gene) is bound by Alendronic acid (Compound) and Alendronic acid may cause a moderate interaction that could exacerbate diseases when taken with Calcium citrate
Etidronic acid (Compound) upregulates PLSCR1 (Gene) and PLSCR1 (Gene) is upregulated by Nisoldipine (Compound) and Nisoldipine may cause a moderate interaction that could exacerbate diseases when taken with Calcium citrate
Etidronic acid (Compound) upregulates XBP1 (Gene) and XBP1 (Gene) is downregulated by Digitoxin (Compound) and Digitoxin may cause a moderate interaction that could exacerbate diseases when taken with Calcium citrate