DDInter385 DDInter790
In many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias. The FDA issued a warning letter regarding this risk to health care professionals and patients.
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of water from the body. Furosemide has a fast onset and short duration of action and has been used safely and effectively in both pediatric and adult patients. The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential. In addition to oral formulations, the solution for intravenous and intramuscular administration is also available, which is typically limited to patients who are unable to take oral medication or for patients in emergency clinical situations.
Cisapride {u} may lead to a major life threatening interaction when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Cisapride {u} may lead to a major life threatening interaction when taken with {v} Metolazone
Metolazone {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Cisapride {u} may lead to a major life threatening interaction when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Bumetanide
Bumetanide {u} (Compound) resembles {v} (Compound) Furosemide
Cisapride {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxcarbazepine
Oxcarbazepine {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Cisapride {u} may lead to a major life threatening interaction when taken with {v} Metolazone
Metolazone {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Furosemide
Cisapride {u} may lead to a major life threatening interaction when taken with {v} Indapamide
Indapamide {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Furosemide
Cisapride {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Cisapride {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxcarbazepine
Oxcarbazepine {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Furosemide
Cisapride {u} may lead to a major life threatening interaction when taken with {v} Metolazone
Metolazone {u} (Compound) binds {v} (Gene) CA5A
CA5A {u} (Gene) is bound by {v} (Compound) Furosemide
Cisapride {u} may lead to a major life threatening interaction when taken with {v} Indapamide
Indapamide {u} (Compound) binds {v} (Gene) CA5A
CA5A {u} (Gene) is bound by {v} (Compound) Furosemide
Cisapride may lead to a major life threatening interaction when taken with Indapamide and Indapamide (Compound) resembles Furosemide (Compound)
Cisapride may lead to a major life threatening interaction when taken with Metolazone and Metolazone (Compound) resembles Indapamide (Compound) and Indapamide (Compound) resembles Furosemide (Compound)
Cisapride may lead to a major life threatening interaction when taken with Indapamide and Indapamide (Compound) resembles Bumetanide (Compound) and Bumetanide (Compound) resembles Furosemide (Compound)
Cisapride may cause a moderate interaction that could exacerbate diseases when taken with Oxcarbazepine and Oxcarbazepine (Compound) resembles Indapamide (Compound) and Indapamide (Compound) resembles Furosemide (Compound)
Cisapride may lead to a major life threatening interaction when taken with Metolazone and Metolazone (Compound) treats hypertension (Disease) and hypertension (Disease) is treated by Furosemide (Compound)
Cisapride may lead to a major life threatening interaction when taken with Indapamide and Indapamide (Compound) treats hypertension (Disease) and hypertension (Disease) is treated by Furosemide (Compound)
Cisapride (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Indapamide (Compound) and Indapamide (Compound) resembles Furosemide (Compound)
Cisapride may cause a moderate interaction that could exacerbate diseases when taken with Oxcarbazepine and Oxcarbazepine (Compound) binds ALB (Gene) and ALB (Gene) is bound by Furosemide (Compound)
Cisapride may lead to a major life threatening interaction when taken with Metolazone and Metolazone (Compound) binds CA5A (Gene) and CA5A (Gene) is bound by Furosemide (Compound)
Cisapride may lead to a major life threatening interaction when taken with Indapamide and Indapamide (Compound) binds CA5A (Gene) and CA5A (Gene) is bound by Furosemide (Compound)