DDInter1855 DDInter1376
Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis. Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain, or first line as a topical treatment of corticosteroid responsive dermatoses. Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and triamcinolone diacetate.[L8246,L8249,L8252,L8255,L8258,L8261,L8264] Triamcinolone was granted FDA approval on 3 December 1957. In October 2021, a suspension of triamcinolone acetonide was approved for suprachoroidal injection - the first suprachoroidal injection to receive FDA approval - for the treatment of patients with macular
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26, 2020.[L12573,L12582] The US approval was followed by the approval in Canada on October 2, 2020. In November 2021, ozanimod was also approved by the European Commission for the treatment of adults with relapsing remitting multiple sclerosis.[L39377,L39382] MS is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Inflammatory bowel disease also a chronic inflammatory condition and can cause persistent abdominal pain, diarrhea, bloody stools, and vomiting. In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard in MS therapy. Studies involving patients with inflammatory bowel disease have also shown promising results.[A189318,A189342]
Triamcinolone {u} (Compound) resembles {v} (Compound) Prednisone
Triamcinolone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fluoxymesterone
Triamcinolone {u} (Compound) resembles {v} (Compound) Budesonide
Triamcinolone {u} (Compound) treats {v} (Disease) multiple sclerosis
Triamcinolone {u} (Compound) binds {v} (Gene) SERPINA6
Triamcinolone {u} (Compound) upregulates {v} (Gene) CDKN1A
Triamcinolone {u} (Compound) palliates {v} (Disease) brain cancer
Triamcinolone {u} (Compound) is included by {v} (Pharmacologic Class) Corticosteroid Hormone Receptor Agonists
Triamcinolone {u} (Compound) downregulates {v} (Gene) GDF15
Triamcinolone {u} (Compound) causes {v} (Side Effect) Acute coronary syndrome
Triamcinolone (Compound) resembles Prednisone (Compound)
Triamcinolone may cause a moderate interaction that could exacerbate diseases when taken with Fluoxymesterone
Triamcinolone (Compound) resembles Budesonide (Compound)
Triamcinolone (Compound) treats multiple sclerosis (Disease)
Triamcinolone (Compound) binds SERPINA6 (Gene)
Triamcinolone (Compound) upregulates CDKN1A (Gene)
Triamcinolone (Compound) palliates brain cancer (Disease)
Triamcinolone (Compound) is included by Corticosteroid Hormone Receptor Agonists (Pharmacologic Class)
Triamcinolone (Compound) downregulates GDF15 (Gene)
Triamcinolone (Compound) causes Acute coronary syndrome (Side Effect)