DDInter350 DDInter655
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
An anthracycline which is the 4&#39;-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Chlorambucil {u} (Compound) treats {v} (Disease) ovarian cancer
ovarian cancer {u} (Disease) is treated by {v} (Compound) Epirubicin
Chlorambucil {u} (Compound) upregulates {v} (Gene) GPC1
GPC1 {u} (Gene) is upregulated by {v} (Compound) Epirubicin
Chlorambucil {u} (Compound) downregulates {v} (Gene) CCNB2
CCNB2 {u} (Gene) is downregulated by {v} (Compound) Epirubicin
Chlorambucil {u} (Compound) upregulates {v} (Gene) FHL2
FHL2 {u} (Gene) is downregulated by {v} (Compound) Epirubicin
Chlorambucil {u} (Compound) causes {v} (Side Effect) Pain
Pain {u} (Side Effect) is caused by {v} (Compound) Epirubicin
Chlorambucil {u} (Compound) resembles {v} (Compound) Melphalan
Melphalan {u} may cause a minor interaction that can limit clinical effects when taken with {v} Epirubicin
Chlorambucil {u} (Compound) downregulates {v} (Gene) AURKA
AURKA {u} (Gene) is bound by {v} (Compound) and {u} (Gene) is downregulated by {v} (Compound) Epirubicin
Chlorambucil {u} (Compound) treats {v} (Disease) ovarian cancer
ovarian cancer {u} (Disease) is treated by {v} (Compound) Doxorubicin
Doxorubicin {u} (Compound) resembles {v} (Compound) Epirubicin
Chlorambucil {u} (Compound) upregulates {v} (Gene) GPC1
GPC1 {u} (Gene) is upregulated by {v} (Compound) Doxorubicin
Doxorubicin {u} (Compound) resembles {v} (Compound) Epirubicin
Chlorambucil {u} (Compound) downregulates {v} (Gene) CCNB2
CCNB2 {u} (Gene) is downregulated by {v} (Compound) Doxorubicin
Doxorubicin {u} (Compound) resembles {v} (Compound) Epirubicin
Chlorambucil (Compound) treats ovarian cancer (Disease) and ovarian cancer (Disease) is treated by Epirubicin (Compound)
Chlorambucil (Compound) upregulates GPC1 (Gene) and GPC1 (Gene) is upregulated by Epirubicin (Compound)
Chlorambucil (Compound) downregulates CCNB2 (Gene) and CCNB2 (Gene) is downregulated by Epirubicin (Compound)
Chlorambucil (Compound) upregulates FHL2 (Gene) and FHL2 (Gene) is downregulated by Epirubicin (Compound)
Chlorambucil (Compound) causes Pain (Side Effect) and Pain (Side Effect) is caused by Epirubicin (Compound)
Chlorambucil (Compound) resembles Melphalan (Compound) and Melphalan may cause a minor interaction that can limit clinical effects when taken with Epirubicin
Chlorambucil (Compound) downregulates AURKA (Gene) and AURKA (Gene) is bound by Epirubicin (Compound) and AURKA (Gene) is downregulated by Epirubicin (Compound)
Chlorambucil (Compound) treats ovarian cancer (Disease) and ovarian cancer (Disease) is treated by Doxorubicin (Compound) and Doxorubicin (Compound) resembles Epirubicin (Compound)
Chlorambucil (Compound) upregulates GPC1 (Gene) and GPC1 (Gene) is upregulated by Doxorubicin (Compound) and Doxorubicin (Compound) resembles Epirubicin (Compound)
Chlorambucil (Compound) downregulates CCNB2 (Gene) and CCNB2 (Gene) is downregulated by Doxorubicin (Compound) and Doxorubicin (Compound) resembles Epirubicin (Compound)