DDInter1417 DDInter1180
Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker. Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric drug. Penbutolol also demonstrates high binding affinity to the 5-hydroxytryptamine receptor 1A with antagonistic effects. This binding characteristic of penbutolol is being investigated for its implications in Antidepressant Therapy. Penbutolol is contraindicated in patients with cardiogenic shock, sinus bradycardia, second and third degree atrioventricular conduction block, bronchial asthma, and those with known hypersensitivity.
Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Penbutolol {u} (Compound) resembles {v} (Compound) Timolol
Penbutolol {u} (Compound) resembles {v} (Compound) Bupranolol
Penbutolol {u} (Compound) treats {v} (Disease) hypertension
Penbutolol {u} (Compound) binds {v} (Gene) ORM1
Penbutolol {u} (Compound) causes {v} (Side Effect) Insomnia
Penbutolol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Levothyroxine
Penbutolol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium oxide
Penbutolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Calcium citrate
Penbutolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nateglinide
Penbutolol {u} may lead to a major life threatening interaction when taken with {v} Dolasetron
Penbutolol (Compound) resembles Timolol (Compound)
Penbutolol (Compound) resembles Bupranolol (Compound)
Penbutolol (Compound) treats hypertension (Disease)
Penbutolol (Compound) binds ORM1 (Gene)
Penbutolol (Compound) causes Insomnia (Side Effect)
Penbutolol may cause a minor interaction that can limit clinical effects when taken with Levothyroxine
Penbutolol may cause a minor interaction that can limit clinical effects when taken with Magnesium oxide
Penbutolol may cause a moderate interaction that could exacerbate diseases when taken with Calcium citrate
Penbutolol may cause a moderate interaction that could exacerbate diseases when taken with Nateglinide
Penbutolol may lead to a major life threatening interaction when taken with Dolasetron