DDInter573 DDInter1662
A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before beneficial effects are noticed. Sertraline displays enhanced safety or tolerability than other classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and other undesirable effects.[A1846,A187075,T28]
Dipyridamole {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Sertraline
Dipyridamole {u} (Compound) causes {v} (Side Effect) Anaphylactic shock
Anaphylactic shock {u} (Side Effect) is caused by {v} (Compound) Sertraline
Dipyridamole {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Maprotiline
Maprotiline {u} (Compound) resembles {v} (Compound) Sertraline
Dipyridamole {u} (Compound) causes {v} (Side Effect) Feeling abnormal
Feeling abnormal {u} (Side Effect) is caused by {v} (Compound) Maprotiline
Maprotiline {u} (Compound) resembles {v} (Compound) Sertraline
Dipyridamole {u} (Compound) binds {v} (Gene) ADA
ADA {u} (Gene) is associated with {v} (Disease) autistic disorder
autistic disorder {u} (Disease) is palliated by {v} (Compound) Sertraline
Dipyridamole {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) regulates {v} (Gene) ALDOC
ALDOC {u} (Gene) is upregulated by {v} (Compound) Sertraline
Dipyridamole {u} (Compound) binds {v} (Gene) ABCC5
ABCC5 {u} (Gene) is regulated by {v} (Gene) NSDHL
NSDHL {u} (Gene) is upregulated by {v} (Compound) Sertraline
Dipyridamole {u} (Compound) binds {v} (Gene) ADA
ADA {u} (Gene) regulates {v} (Gene) IFRD2
IFRD2 {u} (Gene) is downregulated by {v} (Compound) Sertraline
Dipyridamole {u} (Compound) upregulates {v} (Gene) CDK6
CDK6 {u} (Gene) regulates {v} (Gene) MCOLN1
MCOLN1 {u} (Gene) is upregulated by {v} (Compound) Sertraline
Dipyridamole {u} (Compound) palliates {v} (Disease) coronary artery disease
coronary artery disease {u} (Disease) is associated with {v} (Gene) BIRC5
BIRC5 {u} (Gene) is downregulated by {v} (Compound) Sertraline
Dipyridamole (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Sertraline (Compound)
Dipyridamole (Compound) causes Anaphylactic shock (Side Effect) and Anaphylactic shock (Side Effect) is caused by Sertraline (Compound)
Dipyridamole (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Maprotiline (Compound) and Maprotiline (Compound) resembles Sertraline (Compound)
Dipyridamole (Compound) causes Feeling abnormal (Side Effect) and Feeling abnormal (Side Effect) is caused by Maprotiline (Compound) and Maprotiline (Compound) resembles Sertraline (Compound)
Dipyridamole (Compound) binds ADA (Gene) and ADA (Gene) is associated with autistic disorder (Disease) and autistic disorder (Disease) is palliated by Sertraline (Compound)
Dipyridamole (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) regulates ALDOC (Gene) and ALDOC (Gene) is upregulated by Sertraline (Compound)
Dipyridamole (Compound) binds ABCC5 (Gene) and ABCC5 (Gene) is regulated by NSDHL (Gene) and NSDHL (Gene) is upregulated by Sertraline (Compound)
Dipyridamole (Compound) binds ADA (Gene) and ADA (Gene) regulates IFRD2 (Gene) and IFRD2 (Gene) is downregulated by Sertraline (Compound)
Dipyridamole (Compound) upregulates CDK6 (Gene) and CDK6 (Gene) regulates MCOLN1 (Gene) and MCOLN1 (Gene) is upregulated by Sertraline (Compound)
Dipyridamole (Compound) palliates coronary artery disease (Disease) and coronary artery disease (Disease) is associated with BIRC5 (Gene) and BIRC5 (Gene) is downregulated by Sertraline (Compound)