DDInter1557 DDInter832
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Quinine {u} (Compound) resembles {v} (Compound) Quinidine barbiturate
Quinine {u} (Compound) treats {v} (Disease) malaria
Quinine {u} (Compound) binds {v} (Gene) SLC22A4
Quinine {u} (Compound) upregulates {v} (Gene) CPVL
Quinine {u} (Compound) downregulates {v} (Gene) DNAJA3
Quinine {u} (Compound) causes {v} (Side Effect) Optic neuritis
Quinine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Modafinil
Quinine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Doxycycline
Quinine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fostemsavir
Quinine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Aminoglutethimide
Quinine (Compound) resembles Quinidine barbiturate (Compound)
Quinine (Compound) treats malaria (Disease)
Quinine (Compound) binds SLC22A4 (Gene)
Quinine (Compound) upregulates CPVL (Gene)
Quinine (Compound) downregulates DNAJA3 (Gene)
Quinine (Compound) causes Optic neuritis (Side Effect)
Quinine may cause a minor interaction that can limit clinical effects when taken with Modafinil
Quinine may cause a minor interaction that can limit clinical effects when taken with Doxycycline
Quinine may cause a moderate interaction that could exacerbate diseases when taken with Fostemsavir
Quinine may cause a moderate interaction that could exacerbate diseases when taken with Aminoglutethimide