DDInter1144 DDInter1147
Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem cell transplant. It is also used to treat uveal melanoma with unresectable hepatic metastases.
Meningococcal group C polysaccharide is group-specific polysaccharide antigens extracted and purified from *Neisseria meningitidis* serogroup C. *N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup C.
Melphalan {u} (Compound) resembles {v} (Compound) L-Phenylalanine
Melphalan {u} (Compound) resembles {v} (Compound) Levodopa
Melphalan {u} (Compound) treats {v} (Disease) ovarian cancer
Melphalan {u} (Compound) binds {v} (Gene) SLC7A5
Melphalan {u} (Compound) upregulates {v} (Gene) DDB2
Melphalan {u} (Compound) is included by {v} (Pharmacologic Class) Alkylating Activity
Melphalan {u} (Compound) causes {v} (Side Effect) Radiation myelopathy
Melphalan {u} may cause a minor interaction that can limit clinical effects when taken with {v} Norfloxacin
Melphalan {u} may cause a minor interaction that can limit clinical effects when taken with {v} Bortezomib
Melphalan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Efalizumab
Melphalan (Compound) resembles L-Phenylalanine (Compound)
Melphalan (Compound) resembles Levodopa (Compound)
Melphalan (Compound) treats ovarian cancer (Disease)
Melphalan (Compound) binds SLC7A5 (Gene)
Melphalan (Compound) upregulates DDB2 (Gene)
Melphalan (Compound) is included by Alkylating Activity (Pharmacologic Class)
Melphalan (Compound) causes Radiation myelopathy (Side Effect)
Melphalan may cause a minor interaction that can limit clinical effects when taken with Norfloxacin
Melphalan may cause a minor interaction that can limit clinical effects when taken with Bortezomib
Melphalan may cause a moderate interaction that could exacerbate diseases when taken with Efalizumab