DDInter1938 DDInter1710
Vincristine is a vinca alkaloid with formula C46H56N4O10 found in the Madagascar periwinkle, Catharanthus roseus. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer. It has a role as a tubulin modulator, a microtubule-destabilising agent, a plant metabolite, an antineoplastic agent and a drug. It is a methyl ester, an acetate ester, a tertiary alcohol, a member of formamides, an organic heteropentacyclic compound, an organic heterotetracyclic compound, a tertiary amino compound and a vinca alkaloid. It is a conjugate base of a vincristine(2+). It derives from a hydride of a vincaleukoblastine.
A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Vincristine {u} (Compound) upregulates {v} (Gene) WIF1
WIF1 {u} (Gene) is upregulated by {v} (Compound) Stavudine
Vincristine {u} (Compound) upregulates {v} (Gene) ACOT9
ACOT9 {u} (Gene) is downregulated by {v} (Compound) Stavudine
Vincristine {u} (Compound) downregulates {v} (Gene) UBQLN2
UBQLN2 {u} (Gene) is downregulated by {v} (Compound) Stavudine
Vincristine {u} (Compound) causes {v} (Side Effect) Gastrointestinal pain
Gastrointestinal pain {u} (Side Effect) is caused by {v} (Compound) Stavudine
Vincristine {u} (Compound) resembles {v} (Compound) Vinorelbine
Vinorelbine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Stavudine
Vincristine {u} (Compound) resembles {v} (Compound) Vinblastine
Vinblastine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Stavudine
Vincristine {u} (Compound) upregulates {v} (Gene) WIF1
WIF1 {u} (Gene) is upregulated by {v} (Compound) Floxuridine
Floxuridine {u} (Compound) resembles {v} (Compound) Stavudine
Vincristine {u} (Compound) upregulates {v} (Gene) ACOT9
ACOT9 {u} (Gene) regulates {v} (Gene) MAL
MAL {u} (Gene) is upregulated by {v} (Compound) Stavudine
Vincristine {u} (Compound) downregulates {v} (Gene) UBQLN2
UBQLN2 {u} (Gene) is downregulated by {v} (Compound) Trifluridine
Trifluridine {u} (Compound) resembles {v} (Compound) Stavudine
Vincristine {u} (Compound) causes {v} (Side Effect) Gastrointestinal pain
Gastrointestinal pain {u} (Side Effect) is caused by {v} (Compound) Telbivudine
Telbivudine {u} (Compound) resembles {v} (Compound) Stavudine
Vincristine (Compound) upregulates WIF1 (Gene) and WIF1 (Gene) is upregulated by Stavudine (Compound)
Vincristine (Compound) upregulates ACOT9 (Gene) and ACOT9 (Gene) is downregulated by Stavudine (Compound)
Vincristine (Compound) downregulates UBQLN2 (Gene) and UBQLN2 (Gene) is downregulated by Stavudine (Compound)
Vincristine (Compound) causes Gastrointestinal pain (Side Effect) and Gastrointestinal pain (Side Effect) is caused by Stavudine (Compound)
Vincristine (Compound) resembles Vinorelbine (Compound) and Vinorelbine may cause a moderate interaction that could exacerbate diseases when taken with Stavudine
Vincristine (Compound) resembles Vinblastine (Compound) and Vinblastine may cause a moderate interaction that could exacerbate diseases when taken with Stavudine
Vincristine (Compound) upregulates WIF1 (Gene) and WIF1 (Gene) is upregulated by Floxuridine (Compound) and Floxuridine (Compound) resembles Stavudine (Compound)
Vincristine (Compound) upregulates ACOT9 (Gene) and ACOT9 (Gene) regulates MAL (Gene) and MAL (Gene) is upregulated by Stavudine (Compound)
Vincristine (Compound) downregulates UBQLN2 (Gene) and UBQLN2 (Gene) is downregulated by Trifluridine (Compound) and Trifluridine (Compound) resembles Stavudine (Compound)
Vincristine (Compound) causes Gastrointestinal pain (Side Effect) and Gastrointestinal pain (Side Effect) is caused by Telbivudine (Compound) and Telbivudine (Compound) resembles Stavudine (Compound)