DDInter650 DDInter1631
Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with [pseudoephedrine]. Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons, inhibiting norepinephrine reuptake and displacing more norepinephrine from storage vesicles.[A193650,L12972] Ephedrine is used for its vasoconstrictive, positive chronotropic, and positive inotropic effects. Ephedrine and [phenylephrine] are still used to treat hypotension, but their use in other indications has decreased due to the development of more selective adrenergic agonists.[A193701,A193704,L12975] Ephedrine was granted a type 7 FDA
Safinamide is for the treatment of parkinson's disease. It was approved in Europe in February 2015, and in the United States on March 21, 2017.
Ephedrine {u} (Compound) resembles {v} (Compound) Metaraminol
Ephedrine {u} (Compound) resembles {v} (Compound) Etomidate
Ephedrine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amphetamine
Ephedrine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Metamfetamine
Ephedrine {u} (Compound) binds {v} (Gene) ADRB2
Ephedrine {u} (Compound) palliates {v} (Disease) allergic rhinitis
Ephedrine {u} (Compound) downregulates {v} (Gene) COG2
Ephedrine {u} (Compound) causes {v} (Side Effect) Delirium
Ephedrine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Diamorphine
Ephedrine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Dexamethasone
Ephedrine (Compound) resembles Metaraminol (Compound)
Ephedrine (Compound) resembles Etomidate (Compound)
Ephedrine may cause a moderate interaction that could exacerbate diseases when taken with Amphetamine
Ephedrine may cause a moderate interaction that could exacerbate diseases when taken with Metamfetamine
Ephedrine (Compound) binds ADRB2 (Gene)
Ephedrine (Compound) palliates allergic rhinitis (Disease)
Ephedrine (Compound) downregulates COG2 (Gene)
Ephedrine (Compound) causes Delirium (Side Effect)
Ephedrine may cause a minor interaction that can limit clinical effects when taken with Diamorphine
Ephedrine may cause a minor interaction that can limit clinical effects when taken with Dexamethasone