DDInter480 DDInter1180
Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. Darifenacin blocks M3 muscarinic acetylcholine receptors, which mediate bladder muscle contractions. This block reduces the urgency to urinate and so it should not be used in people with urinary retention. It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments.
Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Darifenacin {u} (Compound) resembles {v} (Compound) Fentanyl
Darifenacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mepenzolate
Darifenacin {u} (Compound) binds {v} (Gene) CHRM5
Darifenacin {u} (Compound) upregulates {v} (Gene) MYB
Darifenacin {u} (Compound) is included by {v} (Pharmacologic Class) Cholinergic Muscarinic Antagonists
Darifenacin {u} (Compound) downregulates {v} (Gene) RNF167
Darifenacin {u} (Compound) causes {v} (Side Effect) Oedema peripheral
Darifenacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fluconazole
Darifenacin {u} may lead to a major life threatening interaction when taken with {v} Tamoxifen
Darifenacin {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clidinium
Darifenacin (Compound) resembles Fentanyl (Compound)
Darifenacin may cause a moderate interaction that could exacerbate diseases when taken with Mepenzolate
Darifenacin (Compound) binds CHRM5 (Gene)
Darifenacin (Compound) upregulates MYB (Gene)
Darifenacin (Compound) is included by Cholinergic Muscarinic Antagonists (Pharmacologic Class)
Darifenacin (Compound) downregulates RNF167 (Gene)
Darifenacin (Compound) causes Oedema peripheral (Side Effect)
Darifenacin may cause a moderate interaction that could exacerbate diseases when taken with Fluconazole
Darifenacin may lead to a major life threatening interaction when taken with Tamoxifen
Darifenacin (Compound) resembles Clidinium (Compound) and Darifenacin may cause a moderate interaction that could exacerbate diseases when taken with Clidinium