DDInter475 DDInter119
A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)
Armodafinil is the enantiopure of the wakefulness-promoting agent modafinil (Provigil), and is indicated to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea (OSA), narcolepsy, or shift work disorder (SWD). Research has shown that armodafinil significantly improves driving simulator performance in patients with SWD. Armodafinil consists of the (−)-R-enantiomer of the racemic modafinil. Armodafinil is produced by the pharmaceutical company Cephalon Inc. (a wholly owned subsidiary of Teva Pharmaceutical Industries Ltd.) and was approved by the U.S. Food and Drug Administration (FDA) in June 2007.
Dapsone {u} (Compound) resembles {v} (Compound) Silver sulfadiazine
Dapsone {u} (Compound) resembles {v} (Compound) Sulfamethizole
Dapsone {u} (Compound) treats {v} (Disease) leprosy
Dapsone {u} (Compound) binds {v} (Gene) CYP2E1
Dapsone {u} (Compound) upregulates {v} (Gene) SRC
Dapsone {u} (Compound) is included by {v} (Pharmacologic Class) Sulfones
Dapsone {u} (Compound) downregulates {v} (Gene) CSRP1
Dapsone {u} (Compound) causes {v} (Side Effect) Erythema
Dapsone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Modafinil
Dapsone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Somapacitan
Dapsone (Compound) resembles Silver sulfadiazine (Compound)
Dapsone (Compound) resembles Sulfamethizole (Compound)
Dapsone (Compound) treats leprosy (Disease)
Dapsone (Compound) binds CYP2E1 (Gene)
Dapsone (Compound) upregulates SRC (Gene)
Dapsone (Compound) is included by Sulfones (Pharmacologic Class)
Dapsone (Compound) downregulates CSRP1 (Gene)
Dapsone (Compound) causes Erythema (Side Effect)
Dapsone may cause a minor interaction that can limit clinical effects when taken with Modafinil
Dapsone may cause a moderate interaction that could exacerbate diseases when taken with Somapacitan