DDInter75 DDInter405
An antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.
Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed. It is not known if the drug extends life expectancy. Its potential use in acute myeloid leukaemia (AML) and juvenile myelomonocytic leukaemia (JMML) has been investigated.
Aminosalicylic acid {u} (Compound) binds {v} (Gene) and {u} (Compound) upregulates {v} (Gene) PTGS2
PTGS2 {u} (Gene) is upregulated by {v} (Compound) Clofarabine
Aminosalicylic acid {u} (Compound) downregulates {v} (Gene) CDC20
CDC20 {u} (Gene) is downregulated by {v} (Compound) Clofarabine
Aminosalicylic acid {u} (Compound) causes {v} (Side Effect) Pericarditis
Pericarditis {u} (Side Effect) is caused by {v} (Compound) Clofarabine
Aminosalicylic acid {u} (Compound) resembles {v} (Compound) Diflunisal
Diflunisal {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clofarabine
Aminosalicylic acid {u} (Compound) resembles {v} (Compound) Methyldopa
Methyldopa {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clofarabine
Aminosalicylic acid {u} (Compound) binds {v} (Gene) and {u} (Compound) upregulates {v} (Gene) PTGS2
PTGS2 {u} (Gene) is upregulated by {v} (Compound) Azacitidine
Azacitidine {u} (Compound) resembles {v} (Compound) Clofarabine
Aminosalicylic acid {u} (Compound) downregulates {v} (Gene) CDC20
CDC20 {u} (Gene) is downregulated by {v} (Compound) Adenosine monophosphate
Adenosine monophosphate {u} (Compound) resembles {v} (Compound) Clofarabine
Aminosalicylic acid {u} (Compound) causes {v} (Side Effect) Pericarditis
Pericarditis {u} (Side Effect) is caused by {v} (Compound) Ribavirin
Ribavirin {u} (Compound) resembles {v} (Compound) Clofarabine
Aminosalicylic acid {u} (Compound) causes {v} (Side Effect) Urinary tract disorder
Urinary tract disorder {u} (Side Effect) is caused by {v} (Compound) Nelarabine
Nelarabine {u} (Compound) resembles {v} (Compound) Clofarabine
Aminosalicylic acid {u} (Compound) resembles {v} (Compound) Diflunisal
Diflunisal {u} (Compound) binds {v} (Gene) PTGS2
PTGS2 {u} (Gene) is upregulated by {v} (Compound) Clofarabine
Aminosalicylic acid (Compound) binds PTGS2 (Gene) and Aminosalicylic acid (Compound) upregulates PTGS2 (Gene) and PTGS2 (Gene) is upregulated by Clofarabine (Compound)
Aminosalicylic acid (Compound) downregulates CDC20 (Gene) and CDC20 (Gene) is downregulated by Clofarabine (Compound)
Aminosalicylic acid (Compound) causes Pericarditis (Side Effect) and Pericarditis (Side Effect) is caused by Clofarabine (Compound)
Aminosalicylic acid (Compound) resembles Diflunisal (Compound) and Diflunisal may cause a moderate interaction that could exacerbate diseases when taken with Clofarabine
Aminosalicylic acid (Compound) resembles Methyldopa (Compound) and Methyldopa may cause a moderate interaction that could exacerbate diseases when taken with Clofarabine
Aminosalicylic acid (Compound) binds PTGS2 (Gene) and Aminosalicylic acid (Compound) upregulates PTGS2 (Gene) and PTGS2 (Gene) is upregulated by Azacitidine (Compound) and Azacitidine (Compound) resembles Clofarabine (Compound)
Aminosalicylic acid (Compound) downregulates CDC20 (Gene) and CDC20 (Gene) is downregulated by Adenosine monophosphate (Compound) and Adenosine monophosphate (Compound) resembles Clofarabine (Compound)
Aminosalicylic acid (Compound) causes Pericarditis (Side Effect) and Pericarditis (Side Effect) is caused by Ribavirin (Compound) and Ribavirin (Compound) resembles Clofarabine (Compound)
Aminosalicylic acid (Compound) causes Urinary tract disorder (Side Effect) and Urinary tract disorder (Side Effect) is caused by Nelarabine (Compound) and Nelarabine (Compound) resembles Clofarabine (Compound)
Aminosalicylic acid (Compound) resembles Diflunisal (Compound) and Diflunisal (Compound) binds PTGS2 (Gene) and PTGS2 (Gene) is upregulated by Clofarabine (Compound)