DDInter392 DDInter350
An antineoplastic agent used in the treatment of lymphoproliferative diseases including hairy-cell leukemia.
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Cladribine {u} may lead to a major life threatening interaction when taken with {v} Melphalan
Melphalan {u} (Compound) resembles {v} (Compound) Chlorambucil
Cladribine {u} (Compound) treats {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is treated by {v} (Compound) Chlorambucil
Cladribine {u} (Compound) upregulates {v} (Gene) DDB2
DDB2 {u} (Gene) is upregulated by {v} (Compound) Chlorambucil
Cladribine {u} (Compound) downregulates {v} (Gene) CENPA
CENPA {u} (Gene) is downregulated by {v} (Compound) Chlorambucil
Cladribine {u} (Compound) causes {v} (Side Effect) Hyperuricaemia
Hyperuricaemia {u} (Side Effect) is caused by {v} (Compound) Chlorambucil
Cladribine {u} may lead to a major life threatening interaction when taken with {v} Melphalan
Melphalan {u} (Compound) treats {v} (Disease) ovarian cancer
ovarian cancer {u} (Disease) is treated by {v} (Compound) Chlorambucil
Cladribine {u} (Compound) treats {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is treated by {v} (Compound) Melphalan
Melphalan {u} (Compound) resembles {v} (Compound) Chlorambucil
Cladribine {u} (Compound) upregulates {v} (Gene) DDB2
DDB2 {u} (Gene) is upregulated by {v} (Compound) Melphalan
Melphalan {u} (Compound) resembles {v} (Compound) Chlorambucil
Cladribine {u} (Compound) upregulates {v} (Gene) PHLDA3
PHLDA3 {u} (Gene) interacts with {v} (Gene) LBR
LBR {u} (Gene) is downregulated by {v} (Compound) Chlorambucil
Cladribine {u} (Compound) upregulates {v} (Gene) FDXR
FDXR {u} (Gene) is regulated by {v} (Gene) CDKN1A
CDKN1A {u} (Gene) is upregulated by {v} (Compound) Chlorambucil
Cladribine may lead to a major life threatening interaction when taken with Melphalan and Melphalan (Compound) resembles Chlorambucil (Compound)
Cladribine (Compound) treats hematologic cancer (Disease) and hematologic cancer (Disease) is treated by Chlorambucil (Compound)
Cladribine (Compound) upregulates DDB2 (Gene) and DDB2 (Gene) is upregulated by Chlorambucil (Compound)
Cladribine (Compound) downregulates CENPA (Gene) and CENPA (Gene) is downregulated by Chlorambucil (Compound)
Cladribine (Compound) causes Hyperuricaemia (Side Effect) and Hyperuricaemia (Side Effect) is caused by Chlorambucil (Compound)
Cladribine may lead to a major life threatening interaction when taken with Melphalan and Melphalan (Compound) treats ovarian cancer (Disease) and ovarian cancer (Disease) is treated by Chlorambucil (Compound)
Cladribine (Compound) treats hematologic cancer (Disease) and hematologic cancer (Disease) is treated by Melphalan (Compound) and Melphalan (Compound) resembles Chlorambucil (Compound)
Cladribine (Compound) upregulates DDB2 (Gene) and DDB2 (Gene) is upregulated by Melphalan (Compound) and Melphalan (Compound) resembles Chlorambucil (Compound)
Cladribine (Compound) upregulates PHLDA3 (Gene) and PHLDA3 (Gene) interacts with LBR (Gene) and LBR (Gene) is downregulated by Chlorambucil (Compound)
Cladribine (Compound) upregulates FDXR (Gene) and FDXR (Gene) is regulated by CDKN1A (Gene) and CDKN1A (Gene) is upregulated by Chlorambucil (Compound)