DDInter1311 DDInter1458
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
Phenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist and norepinephrine reuptake inhibitor. It has been used as a decongestant and appetite suppressant. Currently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic strokes.
Norepinephrine {u} (Compound) binds {v} (Gene) ADRB2
ADRB2 {u} (Gene) is bound by {v} (Compound) Phenylpropanolamine
Norepinephrine {u} (Compound) causes {v} (Side Effect) Anxiety
Anxiety {u} (Side Effect) is caused by {v} (Compound) Phenylpropanolamine
Norepinephrine {u} (Compound) resembles {v} (Compound) Salbutamol
Salbutamol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenylpropanolamine
Norepinephrine {u} (Compound) resembles {v} (Compound) Phenylephrine
Phenylephrine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenylpropanolamine
Norepinephrine {u} (Compound) resembles {v} (Compound) Epinephrine
Epinephrine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenylpropanolamine
Norepinephrine {u} (Compound) resembles {v} (Compound) Levonordefrin
Levonordefrin {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenylpropanolamine
Norepinephrine {u} (Compound) binds {v} (Gene) ADRB2
ADRB2 {u} (Gene) is associated with {v} (Disease) obesity
obesity {u} (Disease) is treated by {v} (Compound) Phenylpropanolamine
Norepinephrine {u} (Compound) binds {v} (Gene) ADRA2A
ADRA2A {u} (Gene) interacts with {v} (Gene) ADRB1
ADRB1 {u} (Gene) is bound by {v} (Compound) Phenylpropanolamine
Norepinephrine {u} (Compound) binds {v} (Gene) SLC6A2
SLC6A2 {u} (Gene) is bound by {v} (Compound) Phentermine
Phentermine {u} may lead to a major life threatening interaction when taken with {v} Phenylpropanolamine
Norepinephrine {u} (Compound) binds {v} (Gene) ADRA1A
ADRA1A {u} (Gene) is bound by {v} (Compound) Metaraminol
Metaraminol {u} (Compound) resembles {v} (Compound) Phenylpropanolamine
Norepinephrine (Compound) binds ADRB2 (Gene) and ADRB2 (Gene) is bound by Phenylpropanolamine (Compound)
Norepinephrine (Compound) causes Anxiety (Side Effect) and Anxiety (Side Effect) is caused by Phenylpropanolamine (Compound)
Norepinephrine (Compound) resembles Salbutamol (Compound) and Salbutamol may cause a moderate interaction that could exacerbate diseases when taken with Phenylpropanolamine
Norepinephrine (Compound) resembles Phenylephrine (Compound) and Phenylephrine may cause a moderate interaction that could exacerbate diseases when taken with Phenylpropanolamine
Norepinephrine (Compound) resembles Epinephrine (Compound) and Epinephrine may cause a moderate interaction that could exacerbate diseases when taken with Phenylpropanolamine
Norepinephrine (Compound) resembles Levonordefrin (Compound) and Levonordefrin (Compound) resembles Phenylpropanolamine (Compound) and Levonordefrin may cause a moderate interaction that could exacerbate diseases when taken with Phenylpropanolamine
Norepinephrine (Compound) binds ADRB2 (Gene) and ADRB2 (Gene) is associated with obesity (Disease) and obesity (Disease) is treated by Phenylpropanolamine (Compound)
Norepinephrine (Compound) binds ADRA2A (Gene) and ADRA2A (Gene) interacts with ADRB1 (Gene) and ADRB1 (Gene) is bound by Phenylpropanolamine (Compound)
Norepinephrine (Compound) binds SLC6A2 (Gene) and SLC6A2 (Gene) is bound by Phentermine (Compound) and Phentermine may lead to a major life threatening interaction when taken with Phenylpropanolamine
Norepinephrine (Compound) binds ADRA1A (Gene) and ADRA1A (Gene) is bound by Metaraminol (Compound) and Metaraminol (Compound) resembles Phenylpropanolamine (Compound)