DDInter25 DDInter1763
Acyclovir is a nucleotide analog antiviral used to treat herpes simplex, _Varicella zoster_, herpes zoster, herpes labialis, and acute herpetic keratitis[L7303,L7315,L7318,L7321,L7324,L7327]. Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old. Acyclovir was granted FDA approval on 29 March 1982.
Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). It was developed by Wyeth Pharmaceuticals under the trade name Torisel. Temsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007.
Acyclovir {u} may lead to a major life threatening interaction when taken with {v} Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Acyclovir {u} (Compound) downregulates {v} (Gene) LRP10
LRP10 {u} (Gene) is upregulated by {v} (Compound) Temsirolimus
Acyclovir {u} (Compound) upregulates {v} (Gene) SNX13
SNX13 {u} (Gene) is upregulated by {v} (Compound) Temsirolimus
Acyclovir {u} (Compound) downregulates {v} (Gene) SDHB
SDHB {u} (Gene) is downregulated by {v} (Compound) Temsirolimus
Acyclovir {u} (Compound) causes {v} (Side Effect) Urethral disorder
Urethral disorder {u} (Side Effect) is caused by {v} (Compound) Temsirolimus
Acyclovir {u} may lead to a major life threatening interaction when taken with {v} Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Everolimus
Everolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Acyclovir {u} (Compound) downregulates {v} (Gene) LRP10
LRP10 {u} (Gene) is downregulated by {v} (Compound) Everolimus
Everolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Acyclovir {u} (Compound) upregulates {v} (Gene) SNX13
SNX13 {u} (Gene) is regulated by {v} (Gene) MBTPS1
MBTPS1 {u} (Gene) is upregulated by {v} (Compound) Temsirolimus
Acyclovir {u} (Compound) upregulates {v} (Gene) KLHL9
KLHL9 {u} (Gene) is upregulated by {v} (Compound) Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Acyclovir {u} (Compound) upregulates {v} (Gene) ARNT2
ARNT2 {u} (Gene) is downregulated by {v} (Disease) kidney cancer
kidney cancer {u} (Disease) is treated by {v} (Compound) Temsirolimus
Acyclovir may lead to a major life threatening interaction when taken with Sirolimus and Sirolimus (Compound) resembles Temsirolimus (Compound)
Acyclovir (Compound) downregulates LRP10 (Gene) and LRP10 (Gene) is upregulated by Temsirolimus (Compound)
Acyclovir (Compound) upregulates SNX13 (Gene) and SNX13 (Gene) is upregulated by Temsirolimus (Compound)
Acyclovir (Compound) downregulates SDHB (Gene) and SDHB (Gene) is downregulated by Temsirolimus (Compound)
Acyclovir (Compound) causes Urethral disorder (Side Effect) and Urethral disorder (Side Effect) is caused by Temsirolimus (Compound)
Acyclovir may lead to a major life threatening interaction when taken with Sirolimus and Sirolimus (Compound) resembles Everolimus (Compound) and Everolimus (Compound) resembles Temsirolimus (Compound)
Acyclovir (Compound) downregulates LRP10 (Gene) and LRP10 (Gene) is downregulated by Everolimus (Compound) and Everolimus (Compound) resembles Temsirolimus (Compound)
Acyclovir (Compound) upregulates SNX13 (Gene) and SNX13 (Gene) is regulated by MBTPS1 (Gene) and MBTPS1 (Gene) is upregulated by Temsirolimus (Compound)
Acyclovir (Compound) upregulates KLHL9 (Gene) and KLHL9 (Gene) is upregulated by Sirolimus (Compound) and Sirolimus (Compound) resembles Temsirolimus (Compound)
Acyclovir (Compound) upregulates ARNT2 (Gene) and ARNT2 (Gene) is downregulated by kidney cancer (Disease) and kidney cancer (Disease) is treated by Temsirolimus (Compound)