DDInter245 DDInter1960
Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Ziconotide (also known as SNX-111) is a neurotoxic peptide derived from the cone snail _Conus magus_ comprising 25 amino acids with three disulphide bonds.[A202835, L13389] Other such peptides, collectively termed conotoxins, exist, and some have shown efficacy in binding specific subsets of calcium channels; ziconotide is used in part because it can be synthesized without loss of proper bond formation or structural elements.[A202829, A202832] Ziconotide is used to manage severe chronic pain refractory to other methods, through its ability to inhibit N-type calcium channels involved in nociceptive signalling.[A202829, A202835, A202838, A202841, A202850, A202859, L13389] Ziconotide was granted FDA approval on December 28, 2004 for marketing by TerSera therapeutics LLC. under the name Prialt. To date, ziconotide is the only calcium channel blocking peptide approved for use by the FDA.
Brompheniramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tripelennamine
Brompheniramine {u} (Compound) resembles {v} (Compound) Captodiame
Brompheniramine {u} (Compound) resembles {v} (Compound) Pheniramine
Brompheniramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clofedanol
Brompheniramine {u} (Compound) binds {v} (Gene) CYP3A4
Brompheniramine {u} (Compound) downregulates {v} (Gene) IER3
Brompheniramine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Hyaluronidase
Brompheniramine {u} may lead to a major life threatening interaction when taken with {v} Potassium chloride
Brompheniramine {u} may lead to a major life threatening interaction when taken with {v} Zonisamide
Brompheniramine {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Carbinoxamine
Brompheniramine may cause a moderate interaction that could exacerbate diseases when taken with Tripelennamine
Brompheniramine (Compound) resembles Captodiame (Compound)
Brompheniramine (Compound) resembles Pheniramine (Compound)
Brompheniramine may cause a moderate interaction that could exacerbate diseases when taken with Clofedanol
Brompheniramine (Compound) binds CYP3A4 (Gene)
Brompheniramine (Compound) downregulates IER3 (Gene)
Brompheniramine may cause a minor interaction that can limit clinical effects when taken with Hyaluronidase
Brompheniramine may lead to a major life threatening interaction when taken with Potassium chloride
Brompheniramine may lead to a major life threatening interaction when taken with Zonisamide
Brompheniramine (Compound) resembles Carbinoxamine (Compound) and Brompheniramine may cause a moderate interaction that could exacerbate diseases when taken with Carbinoxamine