DDInter548 DDInter195
A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed) The FDA withdrew its approval for the use of all oral and parenteral drug products containing 25 milligrams or more of diethylstilbestrol per unit dose.
Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.
Diethylstilbestrol {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Betamethasone
Diethylstilbestrol {u} (Compound) downregulates {v} (Gene) RPS4Y1
RPS4Y1 {u} (Gene) is downregulated by {v} (Compound) Betamethasone
Diethylstilbestrol {u} (Compound) resembles {v} (Compound) Ritodrine
Ritodrine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Betamethasone
Diethylstilbestrol {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Budesonide
Budesonide {u} (Compound) resembles {v} (Compound) Betamethasone
Diethylstilbestrol {u} (Compound) binds {v} (Gene) CYP19A1
CYP19A1 {u} (Gene) is bound by {v} (Compound) Testolactone
Testolactone {u} (Compound) resembles {v} (Compound) Betamethasone
Diethylstilbestrol {u} (Compound) downregulates {v} (Gene) RPS4Y1
RPS4Y1 {u} (Gene) is downregulated by {v} (Compound) Fluocinolone Acetonide
Fluocinolone Acetonide {u} (Compound) resembles {v} (Compound) Betamethasone
Diethylstilbestrol {u} (Compound) resembles {v} (Compound) Dienestrol
Dienestrol {u} (Compound) resembles {v} (Compound) Ritodrine
Ritodrine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Betamethasone
Diethylstilbestrol {u} (Compound) resembles {v} (Compound) Ritodrine
Ritodrine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Budesonide
Budesonide {u} (Compound) resembles {v} (Compound) Betamethasone
Diethylstilbestrol {u} (Compound) resembles {v} (Compound) Tamoxifen
Tamoxifen {u} (Compound) treats {v} (Disease) breast cancer
breast cancer {u} (Disease) is palliated by {v} (Compound) Betamethasone
Diethylstilbestrol {u} (Compound) resembles {v} (Compound) Dienestrol
Dienestrol {u} (Compound) upregulates {v} (Gene) NR3C1
NR3C1 {u} (Gene) is bound by {v} (Compound) Betamethasone
Diethylstilbestrol (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Betamethasone (Compound)
Diethylstilbestrol (Compound) downregulates RPS4Y1 (Gene) and RPS4Y1 (Gene) is downregulated by Betamethasone (Compound)
Diethylstilbestrol (Compound) resembles Ritodrine (Compound) and Ritodrine may cause a minor interaction that can limit clinical effects when taken with Betamethasone
Diethylstilbestrol (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Budesonide (Compound) and Budesonide (Compound) resembles Betamethasone (Compound)
Diethylstilbestrol (Compound) binds CYP19A1 (Gene) and CYP19A1 (Gene) is bound by Testolactone (Compound) and Testolactone (Compound) resembles Betamethasone (Compound)
Diethylstilbestrol (Compound) downregulates RPS4Y1 (Gene) and RPS4Y1 (Gene) is downregulated by Fluocinolone Acetonide (Compound) and Fluocinolone Acetonide (Compound) resembles Betamethasone (Compound)
Diethylstilbestrol (Compound) resembles Dienestrol (Compound) and Dienestrol (Compound) resembles Ritodrine (Compound) and Ritodrine may cause a minor interaction that can limit clinical effects when taken with Betamethasone
Diethylstilbestrol (Compound) resembles Ritodrine (Compound) and Ritodrine may cause a minor interaction that can limit clinical effects when taken with Budesonide and Budesonide (Compound) resembles Betamethasone (Compound)
Diethylstilbestrol (Compound) resembles Tamoxifen (Compound) and Tamoxifen (Compound) treats breast cancer (Disease) and breast cancer (Disease) is palliated by Betamethasone (Compound)
Diethylstilbestrol (Compound) resembles Dienestrol (Compound) and Dienestrol (Compound) upregulates NR3C1 (Gene) and NR3C1 (Gene) is bound by Betamethasone (Compound)