DDInter1199 DDInter1016
A quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose]. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. [sucrose]). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in patients with cirrhosis.[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.
Metolazone {u} (Compound) resembles {v} (Compound) Indapamide
Metolazone {u} (Compound) resembles {v} (Compound) Benzthiazide
Metolazone {u} (Compound) treats {v} (Disease) hypertension
Metolazone {u} (Compound) binds {v} (Gene) CA9
Metolazone {u} (Compound) is included by {v} (Pharmacologic Class) Increased Diuresis
Metolazone {u} (Compound) downregulates {v} (Gene) SLC38A1
Metolazone {u} (Compound) causes {v} (Side Effect) Back pain
Metolazone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Scopolamine
Metolazone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Doxycycline
Metolazone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Toremifene
Metolazone (Compound) resembles Indapamide (Compound)
Metolazone (Compound) resembles Benzthiazide (Compound)
Metolazone (Compound) treats hypertension (Disease)
Metolazone (Compound) binds CA9 (Gene)
Metolazone (Compound) is included by Increased Diuresis (Pharmacologic Class)
Metolazone (Compound) downregulates SLC38A1 (Gene)
Metolazone (Compound) causes Back pain (Side Effect)
Metolazone may cause a minor interaction that can limit clinical effects when taken with Scopolamine
Metolazone may cause a minor interaction that can limit clinical effects when taken with Doxycycline
Metolazone may cause a moderate interaction that could exacerbate diseases when taken with Toremifene