DDInter89 DDInter1252
Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Mycophenolic acid is a potent immunosuppressant agent that inhibits _de novo_ purine biosynthesis. It was derived from _Penicillium stoloniferum_, and has also shown antibacterial, antifungal and antiviral properties.. Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. This regimen can be used in place of the older anti-proliferative [azathioprine] due to its stronger immunosuppressive potency. However, mycophenolic acid treatment is more expensive and requires therapeutic drug monitoring to optimize efficacy and minimize toxicity.[A249180,A249185] Mycophenolic acid is available as enteric-coated tablets of delayed-release, in an effort to improve upper gastrointestinal adverse events by delaying mycophenolic acid release until it reaches the small intestine. [Mycophenolate mofetil], a prodrug of mycophenolic acid, is also prescribed to transplant recipients to prevent organ rejection.
Ampicillin {u} (Compound) downregulates {v} (Gene) NT5DC2
NT5DC2 {u} (Gene) is downregulated by {v} (Compound) Mycophenolic acid
Ampicillin {u} (Compound) causes {v} (Side Effect) Stomatitis
Stomatitis {u} (Side Effect) is caused by {v} (Compound) Mycophenolic acid
Ampicillin {u} (Compound) resembles {v} (Compound) Cefamandole
Cefamandole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mycophenolic acid
Ampicillin {u} (Compound) resembles {v} (Compound) Cefaclor
Cefaclor {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mycophenolic acid
Ampicillin {u} (Compound) resembles {v} (Compound) Nafcillin
Nafcillin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mycophenolic acid
Ampicillin {u} (Compound) resembles {v} (Compound) Benzylpenicillin
Benzylpenicillin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mycophenolic acid
Ampicillin {u} (Compound) downregulates {v} (Gene) NT5DC2
NT5DC2 {u} (Gene) is downregulated by {v} (Compound) Mycophenolate mofetil
Mycophenolate mofetil {u} (Compound) resembles {v} (Compound) Mycophenolic acid
Ampicillin {u} (Compound) causes {v} (Side Effect) Stomatitis
Stomatitis {u} (Side Effect) is caused by {v} (Compound) Mycophenolate mofetil
Mycophenolate mofetil {u} (Compound) resembles {v} (Compound) Mycophenolic acid
Ampicillin {u} (Compound) causes {v} (Side Effect) Tongue discolouration
Tongue discolouration {u} (Side Effect) is caused by {v} (Compound) Clarithromycin
Clarithromycin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mycophenolic acid
Ampicillin {u} (Compound) resembles {v} (Compound) Cefamandole
Cefamandole {u} (Compound) resembles {v} (Compound) Cefprozil
Cefprozil {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mycophenolic acid
Ampicillin (Compound) downregulates NT5DC2 (Gene) and NT5DC2 (Gene) is downregulated by Mycophenolic acid (Compound)
Ampicillin (Compound) causes Stomatitis (Side Effect) and Stomatitis (Side Effect) is caused by Mycophenolic acid (Compound)
Ampicillin (Compound) resembles Cefamandole (Compound) and Cefamandole may cause a moderate interaction that could exacerbate diseases when taken with Mycophenolic acid
Ampicillin (Compound) resembles Cefaclor (Compound) and Cefaclor may cause a moderate interaction that could exacerbate diseases when taken with Mycophenolic acid
Ampicillin (Compound) resembles Nafcillin (Compound) and Nafcillin may cause a moderate interaction that could exacerbate diseases when taken with Mycophenolic acid
Ampicillin (Compound) resembles Benzylpenicillin (Compound) and Benzylpenicillin may cause a moderate interaction that could exacerbate diseases when taken with Mycophenolic acid
Ampicillin (Compound) downregulates NT5DC2 (Gene) and NT5DC2 (Gene) is downregulated by Mycophenolate mofetil (Compound) and Mycophenolate mofetil (Compound) resembles Mycophenolic acid (Compound)
Ampicillin (Compound) causes Stomatitis (Side Effect) and Stomatitis (Side Effect) is caused by Mycophenolate mofetil (Compound) and Mycophenolate mofetil (Compound) resembles Mycophenolic acid (Compound)
Ampicillin (Compound) causes Tongue discolouration (Side Effect) and Tongue discolouration (Side Effect) is caused by Clarithromycin (Compound) and Clarithromycin may cause a moderate interaction that could exacerbate diseases when taken with Mycophenolic acid
Ampicillin (Compound) resembles Cefamandole (Compound) and Cefamandole (Compound) resembles Cefprozil (Compound) and Cefprozil may cause a moderate interaction that could exacerbate diseases when taken with Mycophenolic acid