DDInter1276 DDInter1340
Nelfinavir is a potent HIV-1 protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children. Nelfinavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.
Originally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class, and its approval was followed by the formulation of many other proton pump inhibitor drugs . Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults [FDA label].
Nelfinavir {u} may lead to a major life threatening interaction when taken with {v} Pantoprazole
Pantoprazole {u} (Compound) resembles {v} (Compound) Omeprazole
Nelfinavir {u} may lead to a major life threatening interaction when taken with {v} Esomeprazole
Esomeprazole {u} (Compound) resembles {v} (Compound) Omeprazole
Nelfinavir {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Omeprazole
Nelfinavir {u} (Compound) causes {v} (Side Effect) Alanine aminotransferase increased
Alanine aminotransferase increased {u} (Side Effect) is caused by {v} (Compound) Omeprazole
Nelfinavir {u} may lead to a major life threatening interaction when taken with {v} Pantoprazole
Pantoprazole {u} (Compound) resembles {v} (Compound) Esomeprazole
Esomeprazole {u} (Compound) resembles {v} (Compound) Omeprazole
Nelfinavir {u} may lead to a major life threatening interaction when taken with {v} Esomeprazole
Esomeprazole {u} (Compound) resembles {v} (Compound) Pantoprazole
Pantoprazole {u} (Compound) resembles {v} (Compound) Omeprazole
Nelfinavir {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Pantoprazole
Pantoprazole {u} (Compound) resembles {v} (Compound) Omeprazole
Nelfinavir {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Rabeprazole
Rabeprazole {u} (Compound) resembles {v} (Compound) Omeprazole
Nelfinavir {u} (Compound) causes {v} (Side Effect) Alanine aminotransferase increased
Alanine aminotransferase increased {u} (Side Effect) is caused by {v} (Compound) Pantoprazole
Pantoprazole {u} (Compound) resembles {v} (Compound) Omeprazole
Nelfinavir {u} (Compound) causes {v} (Side Effect) Hypoglycaemia
Hypoglycaemia {u} (Side Effect) is caused by {v} (Compound) Esomeprazole
Esomeprazole {u} (Compound) resembles {v} (Compound) Omeprazole
Nelfinavir may lead to a major life threatening interaction when taken with Pantoprazole and Pantoprazole (Compound) resembles Omeprazole (Compound)
Nelfinavir may lead to a major life threatening interaction when taken with Esomeprazole and Esomeprazole (Compound) resembles Omeprazole (Compound)
Nelfinavir (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Omeprazole (Compound)
Nelfinavir (Compound) causes Alanine aminotransferase increased (Side Effect) and Alanine aminotransferase increased (Side Effect) is caused by Omeprazole (Compound)
Nelfinavir may lead to a major life threatening interaction when taken with Pantoprazole and Pantoprazole (Compound) resembles Esomeprazole (Compound) and Esomeprazole (Compound) resembles Omeprazole (Compound)
Nelfinavir may lead to a major life threatening interaction when taken with Esomeprazole and Esomeprazole (Compound) resembles Pantoprazole (Compound) and Pantoprazole (Compound) resembles Omeprazole (Compound)
Nelfinavir (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Pantoprazole (Compound) and Pantoprazole (Compound) resembles Omeprazole (Compound)
Nelfinavir (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Rabeprazole (Compound) and Rabeprazole (Compound) resembles Omeprazole (Compound)
Nelfinavir (Compound) causes Alanine aminotransferase increased (Side Effect) and Alanine aminotransferase increased (Side Effect) is caused by Pantoprazole (Compound) and Pantoprazole (Compound) resembles Omeprazole (Compound)
Nelfinavir (Compound) causes Hypoglycaemia (Side Effect) and Hypoglycaemia (Side Effect) is caused by Esomeprazole (Compound) and Esomeprazole (Compound) resembles Omeprazole (Compound)