DDInter806 DDInter178
An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Bendamustine is a nitrogen mustard drug indicated for use in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed during or within six months of treatment with rituximab or a rituximab-containing regimen. Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases resulting in cell death. It is active against both active and quiescent cells, although the exact mechanism of action is unknown.
Ganciclovir {u} (Compound) resembles {v} (Compound) Penciclovir
Ganciclovir {u} (Compound) resembles {v} (Compound) Valaciclovir
Ganciclovir {u} (Compound) binds {v} (Gene) SLC22A8
Ganciclovir {u} (Compound) upregulates {v} (Gene) PAK1
Ganciclovir {u} (Compound) is included by {v} (Pharmacologic Class) DNA Polymerase Inhibitors
Ganciclovir {u} (Compound) downregulates {v} (Gene) CANT1
Ganciclovir {u} (Compound) causes {v} (Side Effect) Creatinine increased
Ganciclovir {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eribulin
Ganciclovir {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Irinotecan
Ganciclovir {u} may lead to a major life threatening interaction when taken with {v} Certolizumab pegol
Ganciclovir (Compound) resembles Penciclovir (Compound)
Ganciclovir (Compound) resembles Valaciclovir (Compound)
Ganciclovir (Compound) binds SLC22A8 (Gene)
Ganciclovir (Compound) upregulates PAK1 (Gene)
Ganciclovir (Compound) is included by DNA Polymerase Inhibitors (Pharmacologic Class)
Ganciclovir (Compound) downregulates CANT1 (Gene)
Ganciclovir (Compound) causes Creatinine increased (Side Effect)
Ganciclovir may cause a moderate interaction that could exacerbate diseases when taken with Eribulin
Ganciclovir may cause a moderate interaction that could exacerbate diseases when taken with Irinotecan
Ganciclovir may lead to a major life threatening interaction when taken with Certolizumab pegol