DDInter721 DDInter1033
An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous. Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.
Fenoprofen {u} (Compound) causes {v} (Side Effect) Erythema multiforme
Erythema multiforme {u} (Side Effect) is caused by {v} (Compound) Leflunomide
Fenoprofen {u} (Compound) resembles {v} (Compound) Warfarin
Warfarin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Leflunomide
Fenoprofen {u} (Compound) resembles {v} (Compound) Atomoxetine
Atomoxetine {u} may lead to a major life threatening interaction when taken with {v} Leflunomide
Fenoprofen {u} (Compound) causes {v} (Side Effect) Erythema multiforme
Erythema multiforme {u} (Side Effect) is caused by {v} (Compound) Losartan
Losartan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Leflunomide
Fenoprofen {u} (Compound) causes {v} (Side Effect) Discomfort
Discomfort {u} (Side Effect) is caused by {v} (Compound) Telbivudine
Telbivudine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Leflunomide
Fenoprofen {u} (Compound) resembles {v} (Compound) Warfarin
Warfarin {u} (Compound) binds {v} (Gene) CYP2C9
CYP2C9 {u} (Gene) is bound by {v} (Compound) Leflunomide
Fenoprofen {u} (Compound) resembles {v} (Compound) Atomoxetine
Atomoxetine {u} (Compound) causes {v} (Side Effect) Cardiac disorder
Cardiac disorder {u} (Side Effect) is caused by {v} (Compound) Leflunomide
Fenoprofen {u} (Compound) resembles {v} (Compound) Fenbufen
Fenbufen {u} (Compound) resembles {v} (Compound) Ketorolac
Ketorolac {u} may lead to a major life threatening interaction when taken with {v} Leflunomide
Fenoprofen {u} (Compound) causes {v} (Side Effect) Cystitis
Cystitis {u} (Side Effect) is caused by {v} (Compound) Isotretinoin
Isotretinoin {u} may lead to a major life threatening interaction when taken with {v} Leflunomide
Fenoprofen {u} (Compound) causes {v} (Side Effect) Aphthous stomatitis
Aphthous stomatitis {u} (Side Effect) is caused by {v} (Compound) Captopril
Captopril {u} may lead to a major life threatening interaction when taken with {v} Leflunomide
Fenoprofen (Compound) causes Erythema multiforme (Side Effect) and Erythema multiforme (Side Effect) is caused by Leflunomide (Compound)
Fenoprofen (Compound) resembles Warfarin (Compound) and Warfarin may cause a moderate interaction that could exacerbate diseases when taken with Leflunomide
Fenoprofen (Compound) resembles Atomoxetine (Compound) and Atomoxetine may lead to a major life threatening interaction when taken with Leflunomide
Fenoprofen (Compound) causes Erythema multiforme (Side Effect) and Erythema multiforme (Side Effect) is caused by Losartan (Compound) and Losartan may cause a moderate interaction that could exacerbate diseases when taken with Leflunomide
Fenoprofen (Compound) causes Discomfort (Side Effect) and Discomfort (Side Effect) is caused by Telbivudine (Compound) and Telbivudine may cause a moderate interaction that could exacerbate diseases when taken with Leflunomide
Fenoprofen (Compound) resembles Warfarin (Compound) and Warfarin (Compound) binds CYP2C9 (Gene) and CYP2C9 (Gene) is bound by Leflunomide (Compound)
Fenoprofen (Compound) resembles Atomoxetine (Compound) and Atomoxetine (Compound) causes Cardiac disorder (Side Effect) and Cardiac disorder (Side Effect) is caused by Leflunomide (Compound)
Fenoprofen (Compound) resembles Fenbufen (Compound) and Fenbufen (Compound) resembles Ketorolac (Compound) and Ketorolac may lead to a major life threatening interaction when taken with Leflunomide
Fenoprofen (Compound) causes Cystitis (Side Effect) and Cystitis (Side Effect) is caused by Isotretinoin (Compound) and Isotretinoin may lead to a major life threatening interaction when taken with Leflunomide
Fenoprofen (Compound) causes Aphthous stomatitis (Side Effect) and Aphthous stomatitis (Side Effect) is caused by Captopril (Compound) and Captopril may lead to a major life threatening interaction when taken with Leflunomide