DDInter1299 DDInter534
Nitazoxanide belongs to the class of drugs known as _thiazolides_. Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and microaerophilic bacteria, in addition to viruses. This drug is effective in the treatment of gastrointestinal infections including Cryptosporidium parvum or Giardia lamblia in healthy subjects. It is generally well tolerated. Nitazoxanide is a first-line, standard treatment for illness caused by C. parvum or G. lamblia infection in healthy (not immunosuppressed) adults and children and may also be considered in the treatment of illnesses caused by other protozoa or helminths. Recently, this drug has been studied as a broad-spectrum antiviral agent due to its ability
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome. (From Martindale, The Extra Pharmacopoeia, 30th ed, p589) Given diazepam's storied history as a commonly used and effective medication for a variety of indications, contemporary advancements in the formulation and administration of the agent include the development and US FDA approval of an auto-injectable formulation for the rapid treatment of uncontrolled seizures in 2015-2016 . Combining diazepam, a proven effective therapy for acute repetitive seizures, with an auto-injector designed for subcutaneous administration that is quickly and easily administered offers the potential for complete, consistent drug absorption and rapid onset of effect . This current development is subsequently an important addition to the rescue therapy tool chest for patients with epilepsy .
Nitazoxanide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Quazepam
Quazepam {u} (Compound) resembles {v} (Compound) Diazepam
Nitazoxanide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxazepam
Oxazepam {u} (Compound) resembles {v} (Compound) Diazepam
Nitazoxanide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lorazepam
Lorazepam {u} (Compound) resembles {v} (Compound) Diazepam
Nitazoxanide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Temazepam
Temazepam {u} (Compound) resembles {v} (Compound) Diazepam
Nitazoxanide {u} (Compound) causes {v} (Side Effect) Thirst
Thirst {u} (Side Effect) is caused by {v} (Compound) Diazepam
Nitazoxanide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Quazepam
Quazepam {u} (Compound) resembles {v} (Compound) Flunitrazepam
Flunitrazepam {u} (Compound) resembles {v} (Compound) Diazepam
Nitazoxanide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxazepam
Oxazepam {u} (Compound) resembles {v} (Compound) Bromazepam
Bromazepam {u} (Compound) resembles {v} (Compound) Diazepam
Nitazoxanide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lorazepam
Lorazepam {u} (Compound) resembles {v} (Compound) Quazepam
Quazepam {u} (Compound) resembles {v} (Compound) Diazepam
Nitazoxanide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Temazepam
Temazepam {u} (Compound) resembles {v} (Compound) Quazepam
Quazepam {u} (Compound) resembles {v} (Compound) Diazepam
Nitazoxanide {u} (Compound) causes {v} (Side Effect) Thirst
Thirst {u} (Side Effect) is caused by {v} (Compound) Clonazepam
Clonazepam {u} (Compound) resembles {v} (Compound) Diazepam
Nitazoxanide may cause a moderate interaction that could exacerbate diseases when taken with Quazepam and Quazepam (Compound) resembles Diazepam (Compound)
Nitazoxanide may cause a moderate interaction that could exacerbate diseases when taken with Oxazepam and Oxazepam (Compound) resembles Diazepam (Compound)
Nitazoxanide may cause a moderate interaction that could exacerbate diseases when taken with Lorazepam and Lorazepam (Compound) resembles Diazepam (Compound)
Nitazoxanide may cause a moderate interaction that could exacerbate diseases when taken with Temazepam and Temazepam (Compound) resembles Diazepam (Compound)
Nitazoxanide (Compound) causes Thirst (Side Effect) and Thirst (Side Effect) is caused by Diazepam (Compound)
Nitazoxanide may cause a moderate interaction that could exacerbate diseases when taken with Quazepam and Quazepam (Compound) resembles Flunitrazepam (Compound) and Flunitrazepam (Compound) resembles Diazepam (Compound)
Nitazoxanide may cause a moderate interaction that could exacerbate diseases when taken with Oxazepam and Oxazepam (Compound) resembles Bromazepam (Compound) and Bromazepam (Compound) resembles Diazepam (Compound)
Nitazoxanide may cause a moderate interaction that could exacerbate diseases when taken with Lorazepam and Lorazepam (Compound) resembles Quazepam (Compound) and Quazepam (Compound) resembles Diazepam (Compound)
Nitazoxanide may cause a moderate interaction that could exacerbate diseases when taken with Temazepam and Temazepam (Compound) resembles Quazepam (Compound) and Quazepam (Compound) resembles Diazepam (Compound)
Nitazoxanide (Compound) causes Thirst (Side Effect) and Thirst (Side Effect) is caused by Clonazepam (Compound) and Clonazepam (Compound) resembles Diazepam (Compound)