DDInter533 DDInter537
A commonly used x-ray contrast medium. As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation from a variety of causes. Diclofenac was the product of rational drug design based on the structures of [phenylbutazone], [mefenamic acid], and [indomethacin]. The addition of two chlorine groups in the ortho position of the phenyl ring locks the ring in maximal torsion which appears to be related to increased potency. It is often used in combination with [misoprostol] to prevent NSAID-induced gastric ulcers. Diclofenac was first approved by the FDA in July 1988 under the trade name Voltaren, marketed by Novartis (previously Ciba-Geigy).
Diatrizoate {u} (Compound) causes {v} (Side Effect) Chest pain
Chest pain {u} (Side Effect) is caused by {v} (Compound) Diclofenac
Diatrizoate {u} (Compound) causes {v} (Side Effect) Chest pain
Chest pain {u} (Side Effect) is caused by {v} (Compound) Clonidine
Clonidine {u} (Compound) resembles {v} (Compound) Diclofenac
Diatrizoate {u} (Compound) causes {v} (Side Effect) Injury
Injury {u} (Side Effect) is caused by {v} (Compound) Donepezil
Donepezil {u} may cause a minor interaction that can limit clinical effects when taken with {v} Diclofenac
Diatrizoate {u} (Compound) causes {v} (Side Effect) Stinging
Stinging {u} (Side Effect) is caused by {v} (Compound) Bromfenac
Bromfenac {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Diclofenac
Diatrizoate {u} (Compound) causes {v} (Side Effect) Coma
Coma {u} (Side Effect) is caused by {v} (Compound) Lorazepam
Lorazepam {u} (Compound) resembles {v} (Compound) Diclofenac
Diatrizoate {u} (Compound) causes {v} (Side Effect) Azotaemia
Azotaemia {u} (Side Effect) is caused by {v} (Compound) Voriconazole
Voriconazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Diclofenac
Diatrizoate {u} (Compound) causes {v} (Side Effect) Laryngeal oedema
Laryngeal oedema {u} (Side Effect) is caused by {v} (Compound) Nizatidine
Nizatidine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Diclofenac
Diatrizoate {u} (Compound) resembles {v} (Compound) Iodipamide
Iodipamide {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Diclofenac
Diatrizoate {u} (Compound) is included by {v} (Pharmacologic Class) X-Ray Contrast Activity
X-Ray Contrast Activity {u} (Pharmacologic Class) includes {v} (Compound) Iohexol
Iohexol {u} may lead to a major life threatening interaction when taken with {v} Diclofenac
Diatrizoate {u} (Compound) resembles {v} (Compound) Iodipamide
Iodipamide {u} (Compound) causes {v} (Side Effect) Laryngospasm
Laryngospasm {u} (Side Effect) is caused by {v} (Compound) Diclofenac
Diatrizoate (Compound) causes Chest pain (Side Effect) and Chest pain (Side Effect) is caused by Diclofenac (Compound)
Diatrizoate (Compound) causes Chest pain (Side Effect) and Chest pain (Side Effect) is caused by Clonidine (Compound) and Clonidine (Compound) resembles Diclofenac (Compound)
Diatrizoate (Compound) causes Injury (Side Effect) and Injury (Side Effect) is caused by Donepezil (Compound) and Donepezil may cause a minor interaction that can limit clinical effects when taken with Diclofenac
Diatrizoate (Compound) causes Stinging (Side Effect) and Stinging (Side Effect) is caused by Bromfenac (Compound) and Bromfenac may cause a moderate interaction that could exacerbate diseases when taken with Diclofenac
Diatrizoate (Compound) causes Coma (Side Effect) and Coma (Side Effect) is caused by Lorazepam (Compound) and Lorazepam (Compound) resembles Diclofenac (Compound)
Diatrizoate (Compound) causes Azotaemia (Side Effect) and Azotaemia (Side Effect) is caused by Voriconazole (Compound) and Voriconazole may cause a moderate interaction that could exacerbate diseases when taken with Diclofenac
Diatrizoate (Compound) causes Laryngeal oedema (Side Effect) and Laryngeal oedema (Side Effect) is caused by Nizatidine (Compound) and Nizatidine may cause a minor interaction that can limit clinical effects when taken with Diclofenac
Diatrizoate (Compound) resembles Iodipamide (Compound) and Iodipamide (Compound) binds ALB (Gene) and ALB (Gene) is bound by Diclofenac (Compound)
Diatrizoate (Compound) is included by X-Ray Contrast Activity (Pharmacologic Class) and X-Ray Contrast Activity (Pharmacologic Class) includes Iohexol (Compound) and Iohexol may lead to a major life threatening interaction when taken with Diclofenac
Diatrizoate (Compound) resembles Iodipamide (Compound) and Iodipamide (Compound) causes Laryngospasm (Side Effect) and Laryngospasm (Side Effect) is caused by Diclofenac (Compound)