DDInter1705 DDInter278
Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. DNA gyrase is an essential enzyme which controls DNA topology and assists in DNA replication, repair, deactivation, and transcription.
Calcium lactate is a salt that consists of two lactate anions for each calcium cation (Ca2+). It is prepared commercially by the neutralization of lactic acid with calcium carbonate or calcium hydroxide. Approved by the FDA as a direct food substance affirmed as generally recognized as safe, calcium lactate is used as a firming agent, flavoring agent, leavening agent, stabilizer, and thickener . Calcium lactate is also found in daily dietary supplements as a source of calcium. It is also available in various hydrate forms, where calcium lactate pentahydrate is the most common.
Sparfloxacin {u} (Compound) resembles {v} (Compound) Lomefloxacin
Sparfloxacin {u} (Compound) binds {v} (Gene) SLC22A5
Sparfloxacin {u} (Compound) upregulates {v} (Gene) KCTD5
Sparfloxacin {u} (Compound) downregulates {v} (Gene) PKIG
Sparfloxacin {u} (Compound) causes {v} (Side Effect) Atrial flutter
Sparfloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Temozolomide
Sparfloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Paclitaxel
Sparfloxacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Zinc sulfate
Sparfloxacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ibuprofen
Sparfloxacin {u} may lead to a major life threatening interaction when taken with {v} Vandetanib
Sparfloxacin (Compound) resembles Lomefloxacin (Compound)
Sparfloxacin (Compound) binds SLC22A5 (Gene)
Sparfloxacin (Compound) upregulates KCTD5 (Gene)
Sparfloxacin (Compound) downregulates PKIG (Gene)
Sparfloxacin (Compound) causes Atrial flutter (Side Effect)
Sparfloxacin may cause a minor interaction that can limit clinical effects when taken with Temozolomide
Sparfloxacin may cause a minor interaction that can limit clinical effects when taken with Paclitaxel
Sparfloxacin may cause a moderate interaction that could exacerbate diseases when taken with Zinc sulfate
Sparfloxacin may cause a moderate interaction that could exacerbate diseases when taken with Ibuprofen
Sparfloxacin may lead to a major life threatening interaction when taken with Vandetanib