DDInter154 DDInter738
Azelastine is a phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position. It has a role as a H1-receptor antagonist, an anti-allergic agent, an anti-asthmatic drug, a bronchodilator agent, a platelet aggregation inhibitor and an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. It is a member of phthalazines, a tertiary amino compound and a member of monochlorobenzenes.
A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
Azelastine {u} (Compound) resembles {v} (Compound) Cloperastine
Cloperastine {u} (Compound) resembles {v} (Compound) Flavoxate
Azelastine {u} (Compound) causes {v} (Side Effect) Vertigo
Vertigo {u} (Side Effect) is caused by {v} (Compound) Flavoxate
Azelastine {u} (Compound) resembles {v} (Compound) Clemastine
Clemastine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Flavoxate
Azelastine {u} (Compound) resembles {v} (Compound) Cloperastine
Cloperastine {u} (Compound) resembles {v} (Compound) Pipazethate
Pipazethate {u} (Compound) resembles {v} (Compound) Flavoxate
Azelastine {u} (Compound) causes {v} (Side Effect) Vertigo
Vertigo {u} (Side Effect) is caused by {v} (Compound) Raloxifene
Raloxifene {u} (Compound) resembles {v} (Compound) Flavoxate
Azelastine {u} (Compound) causes {v} (Side Effect) Feeling abnormal
Feeling abnormal {u} (Side Effect) is caused by {v} (Compound) Propantheline
Propantheline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Flavoxate
Azelastine {u} (Compound) causes {v} (Side Effect) Nervousness
Nervousness {u} (Side Effect) is caused by {v} (Compound) Cyclizine
Cyclizine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Flavoxate
Azelastine {u} (Compound) binds {v} (Gene) CYP2C8
CYP2C8 {u} (Gene) is bound by {v} (Compound) Raloxifene
Raloxifene {u} (Compound) resembles {v} (Compound) Flavoxate
Azelastine {u} (Compound) resembles {v} (Compound) Clemastine
Clemastine {u} (Compound) resembles {v} (Compound) Cloperastine
Cloperastine {u} (Compound) resembles {v} (Compound) Flavoxate
Azelastine {u} (Compound) binds {v} (Gene) CYP2C8
CYP2C8 {u} (Gene) is bound by {v} (Compound) Brompheniramine
Brompheniramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Flavoxate
Azelastine (Compound) resembles Cloperastine (Compound) and Cloperastine (Compound) resembles Flavoxate (Compound)
Azelastine (Compound) causes Vertigo (Side Effect) and Vertigo (Side Effect) is caused by Flavoxate (Compound)
Azelastine (Compound) resembles Clemastine (Compound) and Clemastine may cause a moderate interaction that could exacerbate diseases when taken with Flavoxate
Azelastine (Compound) resembles Cloperastine (Compound) and Cloperastine (Compound) resembles Pipazethate (Compound) and Pipazethate (Compound) resembles Flavoxate (Compound)
Azelastine (Compound) causes Vertigo (Side Effect) and Vertigo (Side Effect) is caused by Raloxifene (Compound) and Raloxifene (Compound) resembles Flavoxate (Compound)
Azelastine (Compound) causes Feeling abnormal (Side Effect) and Feeling abnormal (Side Effect) is caused by Propantheline (Compound) and Propantheline may cause a moderate interaction that could exacerbate diseases when taken with Flavoxate
Azelastine (Compound) causes Nervousness (Side Effect) and Nervousness (Side Effect) is caused by Cyclizine (Compound) and Cyclizine may cause a moderate interaction that could exacerbate diseases when taken with Flavoxate
Azelastine (Compound) binds CYP2C8 (Gene) and CYP2C8 (Gene) is bound by Raloxifene (Compound) and Raloxifene (Compound) resembles Flavoxate (Compound)
Azelastine (Compound) resembles Clemastine (Compound) and Clemastine (Compound) resembles Cloperastine (Compound) and Cloperastine (Compound) resembles Flavoxate (Compound)
Azelastine (Compound) binds CYP2C8 (Gene) and CYP2C8 (Gene) is bound by Brompheniramine (Compound) and Brompheniramine may cause a moderate interaction that could exacerbate diseases when taken with Flavoxate