DDInter1313 DDInter1016
A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose]. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. [sucrose]). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in patients with cirrhosis.[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.
Norfloxacin {u} (Compound) resembles {v} (Compound) Nalidixic acid
Norfloxacin {u} (Compound) resembles {v} (Compound) Gemifloxacin
Norfloxacin {u} (Compound) binds {v} (Gene) CYP1A1
Norfloxacin {u} (Compound) upregulates {v} (Gene) GHR
Norfloxacin {u} (Compound) is included by {v} (Pharmacologic Class) Quinolones
Norfloxacin {u} (Compound) downregulates {v} (Gene) PRR7
Norfloxacin {u} (Compound) causes {v} (Side Effect) Paraesthesia
Norfloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Melphalan
Norfloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ifosfamide
Norfloxacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Degarelix
Norfloxacin (Compound) resembles Nalidixic acid (Compound)
Norfloxacin (Compound) resembles Gemifloxacin (Compound)
Norfloxacin (Compound) binds CYP1A1 (Gene)
Norfloxacin (Compound) upregulates GHR (Gene)
Norfloxacin (Compound) is included by Quinolones (Pharmacologic Class)
Norfloxacin (Compound) downregulates PRR7 (Gene)
Norfloxacin (Compound) causes Paraesthesia (Side Effect)
Norfloxacin may cause a minor interaction that can limit clinical effects when taken with Melphalan
Norfloxacin may cause a minor interaction that can limit clinical effects when taken with Ifosfamide
Norfloxacin may cause a moderate interaction that could exacerbate diseases when taken with Degarelix