DDInter903 DDInter856
Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families.
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated heparin is more specific than LMWH for thrombin. Furthermore, the effects of UH can typically be reversed by using protamine sulfate.
Icosapent {u} (Compound) resembles {v} (Compound) Icosapent ethyl
Icosapent {u} (Compound) resembles {v} (Compound) Alpha-Linolenic Acid
Icosapent {u} (Compound) binds {v} (Gene) FABP7
Icosapent {u} (Compound) upregulates {v} (Gene) SPDEF
Icosapent {u} (Compound) downregulates {v} (Gene) ACOT9
Icosapent {u} (Compound) causes {v} (Side Effect) Dyspepsia
Icosapent {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Enoxaparin
Icosapent {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Reteplase
Icosapent (Compound) resembles Icosapent ethyl (Compound)
Icosapent (Compound) resembles Alpha-Linolenic Acid (Compound)
Icosapent (Compound) binds FABP7 (Gene)
Icosapent (Compound) upregulates SPDEF (Gene)
Icosapent (Compound) downregulates ACOT9 (Gene)
Icosapent (Compound) causes Dyspepsia (Side Effect)
Icosapent may cause a moderate interaction that could exacerbate diseases when taken with Enoxaparin
Icosapent may cause a moderate interaction that could exacerbate diseases when taken with Reteplase