DDInter1324 DDInter1147
Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is not tumour-specific and can also be found in normal B-cells. Ofatumumab was first approved by the FDA in 2009. It is used in the treatment of recurrent, progressive, or recurrent chronic lymphocytic leukemia (CLL) or CLL in treatment-naive patients in whom fludarabine-based therapy is considered inappropriate. Ofatumumab is used as monotherapy or in combination with other medications, depending on the patient profile and previous treatment history. Although it has a similar molecular mechanism of action as [rituximab], another CD-
Meningococcal group C polysaccharide is group-specific polysaccharide antigens extracted and purified from *Neisseria meningitidis* serogroup C. *N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup C.
Ofatumumab {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ocrelizumab
Ofatumumab {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Topotecan
Ofatumumab {u} may lead to a major life threatening interaction when taken with {v} Teriflunomide
Ofatumumab {u} may lead to a major life threatening interaction when taken with {v} Etanercept
Ofatumumab may cause a moderate interaction that could exacerbate diseases when taken with Ocrelizumab
Ofatumumab may cause a moderate interaction that could exacerbate diseases when taken with Topotecan
Ofatumumab may lead to a major life threatening interaction when taken with Teriflunomide
Ofatumumab may lead to a major life threatening interaction when taken with Etanercept