DDInter1872 DDInter1376
A nicotinic antagonist that has been used as a ganglionic blocker in hypertension, as an adjunct to anesthesia, and to induce hypotension during surgery.
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26, 2020.[L12573,L12582] The US approval was followed by the approval in Canada on October 2, 2020. In November 2021, ozanimod was also approved by the European Commission for the treatment of adults with relapsing remitting multiple sclerosis.[L39377,L39382] MS is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Inflammatory bowel disease also a chronic inflammatory condition and can cause persistent abdominal pain, diarrhea, bloody stools, and vomiting. In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard in MS therapy. Studies involving patients with inflammatory bowel disease have also shown promising results.[A189318,A189342]
Trimethaphan {u} (Compound) resembles {v} (Compound) Alverine
Trimethaphan {u} (Compound) binds {v} (Gene) BCHE
Trimethaphan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Doxepin
Trimethaphan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iloprost
Trimethaphan (Compound) resembles Alverine (Compound)
Trimethaphan (Compound) binds BCHE (Gene)
Trimethaphan may cause a moderate interaction that could exacerbate diseases when taken with Doxepin
Trimethaphan may cause a moderate interaction that could exacerbate diseases when taken with Iloprost