DDInter298 DDInter1086
Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma. Early clinical studies of carboplatin were performed in 1982. Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.
An alkylating agent of value against both hematologic malignancies and solid tumors.
Carboplatin {u} (Compound) treats {v} (Disease) brain cancer
brain cancer {u} (Disease) is treated by {v} (Compound) Lomustine
Carboplatin {u} (Compound) causes {v} (Side Effect) Infection
Infection {u} (Side Effect) is caused by {v} (Compound) Lomustine
Carboplatin {u} (Compound) treats {v} (Disease) brain cancer
brain cancer {u} (Disease) is treated by {v} (Compound) Temozolomide
Temozolomide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lomustine
Carboplatin {u} (Compound) causes {v} (Side Effect) Infection
Infection {u} (Side Effect) is caused by {v} (Compound) Ofloxacin
Ofloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Lomustine
Carboplatin {u} (Compound) causes {v} (Side Effect) Infection
Infection {u} (Side Effect) is caused by {v} (Compound) Floxuridine
Floxuridine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lomustine
Carboplatin {u} (Compound) treats {v} (Disease) brain cancer
brain cancer {u} (Disease) is treated by {v} (Compound) Carmustine
Carmustine {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lomustine
Carboplatin {u} (Compound) causes {v} (Side Effect) Infection
Infection {u} (Side Effect) is caused by {v} (Compound) Radium Ra 223 dichloride
Radium Ra 223 dichloride {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lomustine
Carboplatin {u} (Compound) treats {v} (Disease) bone cancer
bone cancer {u} (Disease) resembles {v} (Disease) brain cancer
brain cancer {u} (Disease) is treated by {v} (Compound) Lomustine
Carboplatin {u} (Compound) treats {v} (Disease) bone cancer
bone cancer {u} (Disease) is associated with {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Lomustine
Carboplatin {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Sparfloxacin
Sparfloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Lomustine
Carboplatin (Compound) treats brain cancer (Disease) and brain cancer (Disease) is treated by Lomustine (Compound)
Carboplatin (Compound) causes Infection (Side Effect) and Infection (Side Effect) is caused by Lomustine (Compound)
Carboplatin (Compound) treats brain cancer (Disease) and brain cancer (Disease) is treated by Temozolomide (Compound) and Temozolomide may cause a moderate interaction that could exacerbate diseases when taken with Lomustine
Carboplatin (Compound) causes Infection (Side Effect) and Infection (Side Effect) is caused by Ofloxacin (Compound) and Ofloxacin may cause a minor interaction that can limit clinical effects when taken with Lomustine
Carboplatin (Compound) causes Infection (Side Effect) and Infection (Side Effect) is caused by Floxuridine (Compound) and Floxuridine may cause a moderate interaction that could exacerbate diseases when taken with Lomustine
Carboplatin (Compound) treats brain cancer (Disease) and brain cancer (Disease) is treated by Carmustine (Compound) and Carmustine (Compound) resembles Lomustine (Compound) and Carmustine may cause a moderate interaction that could exacerbate diseases when taken with Lomustine
Carboplatin (Compound) causes Infection (Side Effect) and Infection (Side Effect) is caused by Radium Ra 223 dichloride (Compound) and Radium Ra 223 dichloride may cause a moderate interaction that could exacerbate diseases when taken with Lomustine
Carboplatin (Compound) treats bone cancer (Disease) and bone cancer (Disease) resembles brain cancer (Disease) and brain cancer (Disease) is treated by Lomustine (Compound)
Carboplatin (Compound) treats bone cancer (Disease) and bone cancer (Disease) is associated with CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Lomustine (Compound)
Carboplatin (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Sparfloxacin (Compound) and Sparfloxacin may cause a minor interaction that can limit clinical effects when taken with Lomustine