DDInter1570 DDInter655
Chronic angina is a common cardiovascular condition affecting millions worldwide and causes significant disability while interfering with daily activities. Ranolazine is a well-tolerated piperazine derivative used for the management of this condition, offering relief from uncomfortable and debilitating symptoms. With a mechanism of action different from drugs used to treat the same condition, ranolazine is a promising anti-anginal therapy. It was originally approved by the FDA in 2006.
An anthracycline which is the 4&#39;-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Ranolazine {u} (Compound) upregulates {v} (Gene) HIST2H2BE
HIST2H2BE {u} (Gene) is upregulated by {v} (Compound) Epirubicin
Ranolazine {u} (Compound) causes {v} (Side Effect) Anxiety
Anxiety {u} (Side Effect) is caused by {v} (Compound) Epirubicin
Ranolazine {u} (Compound) upregulates {v} (Gene) HIST2H2BE
HIST2H2BE {u} (Gene) is upregulated by {v} (Compound) Doxorubicin
Doxorubicin {u} (Compound) resembles {v} (Compound) Epirubicin
Ranolazine {u} (Compound) causes {v} (Side Effect) Anxiety
Anxiety {u} (Side Effect) is caused by {v} (Compound) Doxorubicin
Doxorubicin {u} (Compound) resembles {v} (Compound) Epirubicin
Ranolazine {u} (Compound) resembles {v} (Compound) Guaifenesin
Guaifenesin {u} (Compound) causes {v} (Side Effect) Discomfort
Discomfort {u} (Side Effect) is caused by {v} (Compound) Epirubicin
Ranolazine {u} (Compound) upregulates {v} (Gene) HIST2H2BE
HIST2H2BE {u} (Gene) interacts with {v} (Gene) YWHAG
YWHAG {u} (Gene) is bound by {v} (Compound) Epirubicin
Ranolazine {u} (Compound) upregulates {v} (Gene) NR1H2
NR1H2 {u} (Gene) is regulated by {v} (Gene) SCNN1A
SCNN1A {u} (Gene) is upregulated by {v} (Compound) Epirubicin
Ranolazine {u} (Compound) upregulates {v} (Gene) WDR7
WDR7 {u} (Gene) is regulated by {v} (Gene) DHCR7
DHCR7 {u} (Gene) is bound by {v} (Compound) Epirubicin
Ranolazine {u} (Compound) causes {v} (Side Effect) Anxiety
Anxiety {u} (Side Effect) is caused by {v} (Compound) Trovafloxacin
Trovafloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Epirubicin
Ranolazine {u} (Compound) causes {v} (Side Effect) Pain in extremity
Pain in extremity {u} (Side Effect) is caused by {v} (Compound) Fluvastatin
Fluvastatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Epirubicin
Ranolazine (Compound) upregulates HIST2H2BE (Gene) and HIST2H2BE (Gene) is upregulated by Epirubicin (Compound)
Ranolazine (Compound) causes Anxiety (Side Effect) and Anxiety (Side Effect) is caused by Epirubicin (Compound)
Ranolazine (Compound) upregulates HIST2H2BE (Gene) and HIST2H2BE (Gene) is upregulated by Doxorubicin (Compound) and Doxorubicin (Compound) resembles Epirubicin (Compound)
Ranolazine (Compound) causes Anxiety (Side Effect) and Anxiety (Side Effect) is caused by Doxorubicin (Compound) and Doxorubicin (Compound) resembles Epirubicin (Compound)
Ranolazine (Compound) resembles Guaifenesin (Compound) and Guaifenesin (Compound) causes Discomfort (Side Effect) and Discomfort (Side Effect) is caused by Epirubicin (Compound)
Ranolazine (Compound) upregulates HIST2H2BE (Gene) and HIST2H2BE (Gene) interacts with YWHAG (Gene) and YWHAG (Gene) is bound by Epirubicin (Compound)
Ranolazine (Compound) upregulates NR1H2 (Gene) and NR1H2 (Gene) is regulated by SCNN1A (Gene) and SCNN1A (Gene) is upregulated by Epirubicin (Compound)
Ranolazine (Compound) upregulates WDR7 (Gene) and WDR7 (Gene) is regulated by DHCR7 (Gene) and DHCR7 (Gene) is bound by Epirubicin (Compound)
Ranolazine (Compound) causes Anxiety (Side Effect) and Anxiety (Side Effect) is caused by Trovafloxacin (Compound) and Trovafloxacin may cause a minor interaction that can limit clinical effects when taken with Epirubicin
Ranolazine (Compound) causes Pain in extremity (Side Effect) and Pain in extremity (Side Effect) is caused by Fluvastatin (Compound) and Fluvastatin may cause a moderate interaction that could exacerbate diseases when taken with Epirubicin