DDInter258 DDInter909
A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Imatinib is a small molecule kinase inhibitor that revolutionized the treatment of cancer, particularly chronic myeloid leukemia, in 2001. It was deemed a "miracle drug" due to its clinical success, as oncologist Dr. Brian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more and typically occurred in the first four weeks of therapy".. The discovery of imatinib also established a new group of therapy called "targeted therapy", since treatment can be tailored specifically to the unique cancer genetics of each patient. Imatinib was approved on February 1st ,2001 by the FDA and November 7th, 2001 by the EMA; however, its European approval has been withdrawn in October 2023.[A263036,L49746,L49751]
Butorphanol {u} (Compound) causes {v} (Side Effect) Eye disorder
Eye disorder {u} (Side Effect) is caused by {v} (Compound) Imatinib
Butorphanol {u} (Compound) resembles {v} (Compound) Dextromethorphan
Dextromethorphan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Imatinib
Butorphanol {u} (Compound) resembles {v} (Compound) Naltrexone
Naltrexone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Imatinib
Butorphanol {u} (Compound) causes {v} (Side Effect) Eye disorder
Eye disorder {u} (Side Effect) is caused by {v} (Compound) Citalopram
Citalopram {u} may cause a minor interaction that can limit clinical effects when taken with {v} Imatinib
Butorphanol {u} (Compound) causes {v} (Side Effect) Headache
Headache {u} (Side Effect) is caused by {v} (Compound) Meclizine
Meclizine {u} (Compound) resembles {v} (Compound) Imatinib
Butorphanol {u} (Compound) causes {v} (Side Effect) Hypotension
Hypotension {u} (Side Effect) is caused by {v} (Compound) Donepezil
Donepezil {u} may cause a minor interaction that can limit clinical effects when taken with {v} Imatinib
Butorphanol {u} (Compound) causes {v} (Side Effect) Hypoxia
Hypoxia {u} (Side Effect) is caused by {v} (Compound) Secobarbital
Secobarbital {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Imatinib
Butorphanol {u} (Compound) resembles {v} (Compound) Dextromethorphan
Dextromethorphan {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Imatinib
Butorphanol {u} (Compound) resembles {v} (Compound) Levallorphan
Levallorphan {u} (Compound) resembles {v} (Compound) Dextromethorphan
Dextromethorphan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Imatinib
Butorphanol {u} (Compound) resembles {v} (Compound) Naltrexone
Naltrexone {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Imatinib
Butorphanol (Compound) causes Eye disorder (Side Effect) and Eye disorder (Side Effect) is caused by Imatinib (Compound)
Butorphanol (Compound) resembles Dextromethorphan (Compound) and Dextromethorphan may cause a moderate interaction that could exacerbate diseases when taken with Imatinib
Butorphanol (Compound) resembles Naltrexone (Compound) and Naltrexone may cause a moderate interaction that could exacerbate diseases when taken with Imatinib
Butorphanol (Compound) causes Eye disorder (Side Effect) and Eye disorder (Side Effect) is caused by Citalopram (Compound) and Citalopram may cause a minor interaction that can limit clinical effects when taken with Imatinib
Butorphanol (Compound) causes Headache (Side Effect) and Headache (Side Effect) is caused by Meclizine (Compound) and Meclizine (Compound) resembles Imatinib (Compound)
Butorphanol (Compound) causes Hypotension (Side Effect) and Hypotension (Side Effect) is caused by Donepezil (Compound) and Donepezil may cause a minor interaction that can limit clinical effects when taken with Imatinib
Butorphanol (Compound) causes Hypoxia (Side Effect) and Hypoxia (Side Effect) is caused by Secobarbital (Compound) and Secobarbital may cause a moderate interaction that could exacerbate diseases when taken with Imatinib
Butorphanol (Compound) resembles Dextromethorphan (Compound) and Dextromethorphan (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Imatinib (Compound)
Butorphanol (Compound) resembles Levallorphan (Compound) and Levallorphan (Compound) resembles Dextromethorphan (Compound) and Dextromethorphan may cause a moderate interaction that could exacerbate diseases when taken with Imatinib
Butorphanol (Compound) resembles Naltrexone (Compound) and Naltrexone (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Imatinib (Compound)