DDInter89 DDInter856
Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated heparin is more specific than LMWH for thrombin. Furthermore, the effects of UH can typically be reversed by using protamine sulfate.
Ampicillin {u} (Compound) resembles {v} (Compound) Cefradine
Ampicillin {u} (Compound) resembles {v} (Compound) Mezlocillin
Ampicillin {u} (Compound) binds {v} (Gene) ALB
Ampicillin {u} (Compound) upregulates {v} (Gene) TF
Ampicillin {u} (Compound) is included by {v} (Pharmacologic Class) Penicillins
Ampicillin {u} (Compound) downregulates {v} (Gene) NT5DC2
Ampicillin {u} (Compound) causes {v} (Side Effect) Black hairy tongue
Ampicillin (Compound) resembles Cefradine (Compound)
Ampicillin (Compound) resembles Mezlocillin (Compound)
Ampicillin (Compound) binds ALB (Gene)
Ampicillin (Compound) upregulates TF (Gene)
Ampicillin (Compound) is included by Penicillins (Pharmacologic Class)
Ampicillin (Compound) downregulates NT5DC2 (Gene)
Ampicillin (Compound) causes Black hairy tongue (Side Effect)