DDInter297 DDInter1610
Carbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. The product label for carbinoxamine as an over the counter cough and cold medicine is being modified to state "do not use" in children under 4 years of age in order to prevent and reduce misuse, as many unapproved carbinoxamine-containing preparations contained inappropriate labeling, which promoted unapproved uses (including management of congestion, cough, the common cold, and the use in children under 2 years of age), which can potentially cause serious health risks.
Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type. Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase.
Carbinoxamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tapentadol
Tapentadol {u} (Compound) resembles {v} (Compound) Rivastigmine
Carbinoxamine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Rivastigmine
Carbinoxamine {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Rivastigmine
Carbinoxamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tapentadol
Tapentadol {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Rivastigmine
Carbinoxamine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Pyridostigmine
Pyridostigmine {u} (Compound) resembles {v} (Compound) Rivastigmine
Carbinoxamine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Tapentadol
Tapentadol {u} (Compound) resembles {v} (Compound) Rivastigmine
Carbinoxamine {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Tapentadol
Tapentadol {u} (Compound) resembles {v} (Compound) Rivastigmine
Carbinoxamine {u} (Compound) causes {v} (Side Effect) Pollakiuria
Pollakiuria {u} (Side Effect) is caused by {v} (Compound) Pyridostigmine
Pyridostigmine {u} (Compound) resembles {v} (Compound) Rivastigmine
Carbinoxamine {u} (Compound) resembles {v} (Compound) Bisacodyl
Bisacodyl {u} (Compound) downregulates {v} (Gene) IFRD2
IFRD2 {u} (Gene) is downregulated by {v} (Compound) Rivastigmine
Carbinoxamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tapentadol
Tapentadol {u} (Compound) causes {v} (Side Effect) Pruritus
Pruritus {u} (Side Effect) is caused by {v} (Compound) Rivastigmine
Carbinoxamine may cause a moderate interaction that could exacerbate diseases when taken with Tapentadol and Tapentadol (Compound) resembles Rivastigmine (Compound)
Carbinoxamine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Rivastigmine (Compound)
Carbinoxamine (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Rivastigmine (Compound)
Carbinoxamine may cause a moderate interaction that could exacerbate diseases when taken with Tapentadol and Tapentadol (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Rivastigmine (Compound)
Carbinoxamine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Pyridostigmine (Compound) and Pyridostigmine (Compound) resembles Rivastigmine (Compound)
Carbinoxamine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Tapentadol (Compound) and Tapentadol (Compound) resembles Rivastigmine (Compound)
Carbinoxamine (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Tapentadol (Compound) and Tapentadol (Compound) resembles Rivastigmine (Compound)
Carbinoxamine (Compound) causes Pollakiuria (Side Effect) and Pollakiuria (Side Effect) is caused by Pyridostigmine (Compound) and Pyridostigmine (Compound) resembles Rivastigmine (Compound)
Carbinoxamine (Compound) resembles Bisacodyl (Compound) and Bisacodyl (Compound) downregulates IFRD2 (Gene) and IFRD2 (Gene) is downregulated by Rivastigmine (Compound)
Carbinoxamine may cause a moderate interaction that could exacerbate diseases when taken with Tapentadol and Tapentadol (Compound) causes Pruritus (Side Effect) and Pruritus (Side Effect) is caused by Rivastigmine (Compound)