DDInter743 DDInter1570
Fluconazole, commonly known as _Diflucan_, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole]. Fluconazole has many advantages over the other antifungal drugs including the option of oral administration. The side effect profile of this drug is minimal. It has been demonstrated as an efficacious treatment for vaginal yeast infections in one single dose.
Chronic angina is a common cardiovascular condition affecting millions worldwide and causes significant disability while interfering with daily activities. Ranolazine is a well-tolerated piperazine derivative used for the management of this condition, offering relief from uncomfortable and debilitating symptoms. With a mechanism of action different from drugs used to treat the same condition, ranolazine is a promising anti-anginal therapy. It was originally approved by the FDA in 2006.
Fluconazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Carvedilol
Carvedilol {u} (Compound) resembles {v} (Compound) Ranolazine
Fluconazole {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Ranolazine
Fluconazole {u} (Compound) causes {v} (Side Effect) Mediastinal disorder
Mediastinal disorder {u} (Side Effect) is caused by {v} (Compound) Ranolazine
Fluconazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Carvedilol
Carvedilol {u} (Compound) resembles {v} (Compound) Guaifenesin
Guaifenesin {u} (Compound) resembles {v} (Compound) Ranolazine
Fluconazole {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Bupivacaine
Bupivacaine {u} (Compound) resembles {v} (Compound) Ranolazine
Fluconazole {u} (Compound) causes {v} (Side Effect) Mediastinal disorder
Mediastinal disorder {u} (Side Effect) is caused by {v} (Compound) Carvedilol
Carvedilol {u} (Compound) resembles {v} (Compound) Ranolazine
Fluconazole {u} (Compound) causes {v} (Side Effect) Vomiting
Vomiting {u} (Side Effect) is caused by {v} (Compound) Guaifenesin
Guaifenesin {u} (Compound) resembles {v} (Compound) Ranolazine
Fluconazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lidocaine
Lidocaine {u} (Compound) resembles {v} (Compound) Bupivacaine
Bupivacaine {u} (Compound) resembles {v} (Compound) Ranolazine
Fluconazole {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Propranolol
Propranolol {u} (Compound) resembles {v} (Compound) Ranolazine
Fluconazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lidocaine
Lidocaine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Carvedilol
Carvedilol {u} (Compound) resembles {v} (Compound) Ranolazine
Fluconazole may cause a moderate interaction that could exacerbate diseases when taken with Carvedilol and Carvedilol (Compound) resembles Ranolazine (Compound)
Fluconazole (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Ranolazine (Compound)
Fluconazole (Compound) causes Mediastinal disorder (Side Effect) and Mediastinal disorder (Side Effect) is caused by Ranolazine (Compound)
Fluconazole may cause a moderate interaction that could exacerbate diseases when taken with Carvedilol and Carvedilol (Compound) resembles Guaifenesin (Compound) and Guaifenesin (Compound) resembles Ranolazine (Compound)
Fluconazole (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Bupivacaine (Compound) and Bupivacaine (Compound) resembles Ranolazine (Compound)
Fluconazole (Compound) causes Mediastinal disorder (Side Effect) and Mediastinal disorder (Side Effect) is caused by Carvedilol (Compound) and Carvedilol (Compound) resembles Ranolazine (Compound)
Fluconazole (Compound) causes Vomiting (Side Effect) and Vomiting (Side Effect) is caused by Guaifenesin (Compound) and Guaifenesin (Compound) resembles Ranolazine (Compound)
Fluconazole may cause a moderate interaction that could exacerbate diseases when taken with Lidocaine and Lidocaine (Compound) resembles Bupivacaine (Compound) and Bupivacaine (Compound) resembles Ranolazine (Compound)
Fluconazole (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Propranolol (Compound) and Propranolol (Compound) resembles Ranolazine (Compound)
Fluconazole may cause a moderate interaction that could exacerbate diseases when taken with Lidocaine and Lidocaine may cause a moderate interaction that could exacerbate diseases when taken with Carvedilol and Carvedilol (Compound) resembles Ranolazine (Compound)