DDInter1515 DDInter131
A synthetic anti-inflammatory glucocorticoid derived from [cortisone]. It is biologically inert and converted to [prednisolone] in the liver. Prednisone was granted FDA approval on 21 February 1955.
Atezolizumab is a humanized monoclonal antibody used to prevent the interaction of PD-L1 and PD-1, removing inhibition of immune responses seen in some cancers.[A18493,L7489] This medication is reserved for patients whose tumors express PD-L1, cannot receive platinum-based chemotherapy, or whose tumors do not respond to platinum-based chemotherapy. Atezolizumab was granted FDA approval on 18 October 2016. In November 2022, the manufacturer (Genentech) voluntarily withdrew the use of atezolizumab for the treatment of urothelial carcinoma, previously approved under the FDA's Accelerated Approval Program. The rest of atezolizumab indications remain unaffected.
Prednisone {u} (Compound) resembles {v} (Compound) Triamcinolone
Prednisone {u} (Compound) resembles {v} (Compound) Testolactone
Prednisone {u} (Compound) treats {v} (Disease) psoriasis
Prednisone {u} (Compound) binds {v} (Gene) CYP3A4
Prednisone {u} (Compound) upregulates {v} (Gene) VAPB
Prednisone {u} (Compound) palliates {v} (Disease) osteoarthritis
Prednisone {u} (Compound) is included by {v} (Pharmacologic Class) Corticosteroid Hormone Receptor Agonists
Prednisone {u} (Compound) downregulates {v} (Gene) ZDHHC6
Prednisone {u} (Compound) causes {v} (Side Effect) Arthralgia
Prednisone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Aluminum hydroxide
Prednisone (Compound) resembles Triamcinolone (Compound)
Prednisone (Compound) resembles Testolactone (Compound)
Prednisone (Compound) treats psoriasis (Disease)
Prednisone (Compound) binds CYP3A4 (Gene)
Prednisone (Compound) upregulates VAPB (Gene)
Prednisone (Compound) palliates osteoarthritis (Disease)
Prednisone (Compound) is included by Corticosteroid Hormone Receptor Agonists (Pharmacologic Class)
Prednisone (Compound) downregulates ZDHHC6 (Gene)
Prednisone (Compound) causes Arthralgia (Side Effect)
Prednisone may cause a minor interaction that can limit clinical effects when taken with Aluminum hydroxide