DDInter901 DDInter1016
Ibutilide is a Class III antiarrhythmic agent available in intravenous formulations. It is indicated for the conversion of acute atrial flutter and recent onset atrial fibrillation to normal sinus rhythm (NSR).
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose]. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. [sucrose]). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in patients with cirrhosis.[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.
Ibutilide {u} (Compound) resembles {v} (Compound) Dronedarone
Ibutilide {u} (Compound) binds {v} (Gene) KCNH7
Ibutilide {u} (Compound) causes {v} (Side Effect) Bradycardia
Ibutilide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metronidazole
Ibutilide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Thalidomide
Ibutilide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lidocaine
Ibutilide {u} may lead to a major life threatening interaction when taken with {v} Mefloquine
Ibutilide {u} may lead to a major life threatening interaction when taken with {v} Anagrelide
Ibutilide (Compound) resembles Dronedarone (Compound)
Ibutilide (Compound) binds KCNH7 (Gene)
Ibutilide (Compound) causes Bradycardia (Side Effect)
Ibutilide may cause a minor interaction that can limit clinical effects when taken with Metronidazole
Ibutilide may cause a moderate interaction that could exacerbate diseases when taken with Thalidomide
Ibutilide may cause a moderate interaction that could exacerbate diseases when taken with Lidocaine
Ibutilide may lead to a major life threatening interaction when taken with Mefloquine
Ibutilide may lead to a major life threatening interaction when taken with Anagrelide