DDInter268 DDInter265
Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D<sub>3</sub>, 1,25-dihydroxyvitamin D<sub>3</sub>. It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to (vitamin D3) in the skin, which is then converted to in the liver and kidneys. undergoes hydroxylation to form calcitriol via 1α-hydroxylase (CYP27B1) activity. Calcitriol is considered to be the most potent metabolite of vitamin D in humans. Renal production of calcitriol is stimulated in response to PTH
The major circulating metabolite of vitamin D3 (cholecalciferol). It is produced in the liver and is the best indicator of the body's vitamin D stores. It is effective in the treatment of rickets and osteomalacia, both in azotemic and non-azotemic patients. Calcifediol also has mineralizing properties.
Calcitriol {u} (Compound) resembles {v} (Compound) Calcifediol
Calcitriol {u} (Compound) resembles {v} (Compound) Calcipotriol
Calcipotriol {u} (Compound) resembles {v} (Compound) Calcifediol
Calcitriol {u} (Compound) resembles {v} (Compound) Dihydrotachysterol
Dihydrotachysterol {u} may lead to a major life threatening interaction when taken with {v} Calcifediol
Calcitriol {u} (Compound) binds {v} (Gene) CYP24A1
CYP24A1 {u} (Gene) is bound by {v} (Compound) Calcifediol
Calcitriol {u} (Compound) resembles {v} (Compound) Cholecalciferol
Cholecalciferol {u} (Compound) resembles {v} (Compound) and {u} may lead to a major life threatening interaction when taken with {v} Calcifediol
Calcitriol {u} (Compound) resembles {v} (Compound) Calcipotriol
Calcipotriol {u} (Compound) resembles {v} (Compound) Dihydrotachysterol
Dihydrotachysterol {u} may lead to a major life threatening interaction when taken with {v} Calcifediol
Calcitriol {u} (Compound) resembles {v} (Compound) Dihydrotachysterol
Dihydrotachysterol {u} (Compound) resembles {v} (Compound) Calcipotriol
Calcipotriol {u} (Compound) resembles {v} (Compound) Calcifediol
Calcitriol {u} (Compound) resembles {v} (Compound) Alfacalcidol
Alfacalcidol {u} (Compound) resembles {v} (Compound) Calcipotriol
Calcipotriol {u} (Compound) resembles {v} (Compound) Calcifediol
Calcitriol {u} (Compound) binds {v} (Gene) CYP24A1
CYP24A1 {u} (Gene) is bound by {v} (Compound) Calcipotriol
Calcipotriol {u} (Compound) resembles {v} (Compound) Calcifediol
Calcitriol {u} (Compound) treats {v} (Disease) psoriasis
psoriasis {u} (Disease) is treated by {v} (Compound) Calcipotriol
Calcipotriol {u} (Compound) resembles {v} (Compound) Calcifediol
Calcitriol (Compound) resembles Calcifediol (Compound)
Calcitriol (Compound) resembles Calcipotriol (Compound) and Calcipotriol (Compound) resembles Calcifediol (Compound)
Calcitriol (Compound) resembles Dihydrotachysterol (Compound) and Dihydrotachysterol may lead to a major life threatening interaction when taken with Calcifediol
Calcitriol (Compound) binds CYP24A1 (Gene) and CYP24A1 (Gene) is bound by Calcifediol (Compound)
Calcitriol (Compound) resembles Cholecalciferol (Compound) and Cholecalciferol (Compound) resembles Calcifediol (Compound) and Cholecalciferol may lead to a major life threatening interaction when taken with Calcifediol
Calcitriol (Compound) resembles Calcipotriol (Compound) and Calcipotriol (Compound) resembles Dihydrotachysterol (Compound) and Dihydrotachysterol may lead to a major life threatening interaction when taken with Calcifediol
Calcitriol (Compound) resembles Dihydrotachysterol (Compound) and Dihydrotachysterol (Compound) resembles Calcipotriol (Compound) and Calcipotriol (Compound) resembles Calcifediol (Compound)
Calcitriol (Compound) resembles Alfacalcidol (Compound) and Alfacalcidol (Compound) resembles Calcipotriol (Compound) and Calcipotriol (Compound) resembles Calcifediol (Compound)
Calcitriol (Compound) binds CYP24A1 (Gene) and CYP24A1 (Gene) is bound by Calcipotriol (Compound) and Calcipotriol (Compound) resembles Calcifediol (Compound)
Calcitriol (Compound) treats psoriasis (Disease) and psoriasis (Disease) is treated by Calcipotriol (Compound) and Calcipotriol (Compound) resembles Calcifediol (Compound)