DDInter704 DDInter804
Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and not on the mTORC2 protein.
Gallium nitrate is a nitrate salt of , a heavy metal that has been used as a diagnostic agent. Gallium nitrate is reported to possess antiresorptive and hypocalcemic effects on bone. GANITE, a product of gallium nitrate previously used to treat cancer-related hypercalcemia, was discontinued from marketing in the US for reasons other than safety or effectiveness. Apart from cancer-related hypercalcemia, gallium nitrate has been studied in arthritis, autoimmune disorders, and tumours.
Everolimus {u} (Compound) causes {v} (Side Effect) Tachycardia
Tachycardia {u} (Side Effect) is caused by {v} (Compound) Gallium nitrate
Everolimus {u} (Compound) resembles {v} (Compound) Sirolimus
Sirolimus {u} may lead to a major life threatening interaction when taken with {v} Gallium nitrate
Everolimus {u} (Compound) causes {v} (Side Effect) Tachycardia
Tachycardia {u} (Side Effect) is caused by {v} (Compound) Clofarabine
Clofarabine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Gallium nitrate
Everolimus {u} (Compound) causes {v} (Side Effect) Hypophosphataemia
Hypophosphataemia {u} (Side Effect) is caused by {v} (Compound) Amphotericin B
Amphotericin B {u} may lead to a major life threatening interaction when taken with {v} Gallium nitrate
Everolimus {u} (Compound) upregulates {v} (Gene) UBQLN2
UBQLN2 {u} (Gene) regulates {v} (Gene) RRM2
RRM2 {u} (Gene) is bound by {v} (Compound) Gallium nitrate
Everolimus {u} (Compound) resembles {v} (Compound) Sirolimus
Sirolimus {u} (Compound) causes {v} (Side Effect) Tachycardia
Tachycardia {u} (Side Effect) is caused by {v} (Compound) Gallium nitrate
Everolimus {u} (Compound) downregulates {v} (Gene) B4GAT1
B4GAT1 {u} (Gene) is regulated by {v} (Gene) RRM2
RRM2 {u} (Gene) is bound by {v} (Compound) Gallium nitrate
Everolimus {u} (Compound) upregulates {v} (Gene) UBQLN2
UBQLN2 {u} (Gene) is regulated by {v} (Gene) TF
TF {u} (Gene) is bound by {v} (Compound) Gallium nitrate
Everolimus {u} (Compound) upregulates {v} (Gene) UBQLN2
UBQLN2 {u} (Gene) is downregulated by {v} (Compound) Sulfasalazine
Sulfasalazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Gallium nitrate
Everolimus {u} (Compound) downregulates {v} (Gene) B4GAT1
B4GAT1 {u} (Gene) is downregulated by {v} (Compound) Sirolimus
Sirolimus {u} may lead to a major life threatening interaction when taken with {v} Gallium nitrate
Everolimus (Compound) causes Tachycardia (Side Effect) and Tachycardia (Side Effect) is caused by Gallium nitrate (Compound)
Everolimus (Compound) resembles Sirolimus (Compound) and Sirolimus may lead to a major life threatening interaction when taken with Gallium nitrate
Everolimus (Compound) causes Tachycardia (Side Effect) and Tachycardia (Side Effect) is caused by Clofarabine (Compound) and Clofarabine may cause a moderate interaction that could exacerbate diseases when taken with Gallium nitrate
Everolimus (Compound) causes Hypophosphataemia (Side Effect) and Hypophosphataemia (Side Effect) is caused by Amphotericin B (Compound) and Amphotericin B may lead to a major life threatening interaction when taken with Gallium nitrate
Everolimus (Compound) upregulates UBQLN2 (Gene) and UBQLN2 (Gene) regulates RRM2 (Gene) and RRM2 (Gene) is bound by Gallium nitrate (Compound)
Everolimus (Compound) resembles Sirolimus (Compound) and Sirolimus (Compound) causes Tachycardia (Side Effect) and Tachycardia (Side Effect) is caused by Gallium nitrate (Compound)
Everolimus (Compound) downregulates B4GAT1 (Gene) and B4GAT1 (Gene) is regulated by RRM2 (Gene) and RRM2 (Gene) is bound by Gallium nitrate (Compound)
Everolimus (Compound) upregulates UBQLN2 (Gene) and UBQLN2 (Gene) is regulated by TF (Gene) and TF (Gene) is bound by Gallium nitrate (Compound)
Everolimus (Compound) upregulates UBQLN2 (Gene) and UBQLN2 (Gene) is downregulated by Sulfasalazine (Compound) and Sulfasalazine may cause a moderate interaction that could exacerbate diseases when taken with Gallium nitrate
Everolimus (Compound) downregulates B4GAT1 (Gene) and B4GAT1 (Gene) is downregulated by Sirolimus (Compound) and Sirolimus may lead to a major life threatening interaction when taken with Gallium nitrate