DDInter1091 DDInter119
Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Armodafinil is the enantiopure of the wakefulness-promoting agent modafinil (Provigil), and is indicated to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea (OSA), narcolepsy, or shift work disorder (SWD). Research has shown that armodafinil significantly improves driving simulator performance in patients with SWD. Armodafinil consists of the (−)-R-enantiomer of the racemic modafinil. Armodafinil is produced by the pharmaceutical company Cephalon Inc. (a wholly owned subsidiary of Teva Pharmaceutical Industries Ltd.) and was approved by the U.S. Food and Drug Administration (FDA) in June 2007.
Loratadine {u} (Compound) resembles {v} (Compound) Desloratadine
Loratadine {u} (Compound) resembles {v} (Compound) Ketotifen
Loratadine {u} (Compound) treats {v} (Disease) asthma
Loratadine {u} (Compound) binds {v} (Gene) CYP3A4
Loratadine {u} (Compound) upregulates {v} (Gene) DDIT4
Loratadine {u} (Compound) downregulates {v} (Gene) TUBB6
Loratadine {u} (Compound) causes {v} (Side Effect) Syncope
Loratadine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Clarithromycin
Loratadine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Fluconazole
Loratadine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Terbinafine
Loratadine (Compound) resembles Desloratadine (Compound)
Loratadine (Compound) resembles Ketotifen (Compound)
Loratadine (Compound) treats asthma (Disease)
Loratadine (Compound) binds CYP3A4 (Gene)
Loratadine (Compound) upregulates DDIT4 (Gene)
Loratadine (Compound) downregulates TUBB6 (Gene)
Loratadine (Compound) causes Syncope (Side Effect)
Loratadine may cause a minor interaction that can limit clinical effects when taken with Clarithromycin
Loratadine may cause a minor interaction that can limit clinical effects when taken with Fluconazole
Loratadine may cause a moderate interaction that could exacerbate diseases when taken with Terbinafine