DDInter1432 DDInter1055
An antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.
Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones such as [gatifloxacin] and [moxifloxacin], is a member of the third generation of fluoroquinolones, colloquially referred to as the "respiratory quinolones" due to improved activity against gram-positive bacteria commonly implicated in respiratory infections.[A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and several South American countries soon after.
Perphenazine {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Levofloxacin
Perphenazine {u} (Compound) causes {v} (Side Effect) Dysphagia
Dysphagia {u} (Side Effect) is caused by {v} (Compound) Levofloxacin
Perphenazine {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Enoxacin
Enoxacin {u} (Compound) resembles {v} (Compound) Levofloxacin
Perphenazine {u} (Compound) causes {v} (Side Effect) Dysphagia
Dysphagia {u} (Side Effect) is caused by {v} (Compound) Ciprofloxacin
Ciprofloxacin {u} (Compound) resembles {v} (Compound) Levofloxacin
Perphenazine {u} (Compound) causes {v} (Side Effect) Hyperkinesia
Hyperkinesia {u} (Side Effect) is caused by {v} (Compound) Sparfloxacin
Sparfloxacin {u} (Compound) resembles {v} (Compound) Levofloxacin
Perphenazine {u} (Compound) resembles {v} (Compound) Triflupromazine
Triflupromazine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Levofloxacin
Perphenazine {u} (Compound) resembles {v} (Compound) Hydroxyzine
Hydroxyzine {u} (Compound) causes {v} (Side Effect) Drowsiness
Drowsiness {u} (Side Effect) is caused by {v} (Compound) Levofloxacin
Perphenazine {u} (Compound) resembles {v} (Compound) Propericiazine
Propericiazine {u} (Compound) causes {v} (Side Effect) Aggression
Aggression {u} (Side Effect) is caused by {v} (Compound) Levofloxacin
Perphenazine {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is associated with {v} (Disease) chronic obstructive pulmonary disease
chronic obstructive pulmonary disease {u} (Disease) is palliated by {v} (Compound) Levofloxacin
Perphenazine {u} (Compound) resembles {v} (Compound) Ethopropazine
Ethopropazine {u} (Compound) upregulates {v} (Gene) GPATCH8
GPATCH8 {u} (Gene) is upregulated by {v} (Compound) Levofloxacin
Perphenazine (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Levofloxacin (Compound)
Perphenazine (Compound) causes Dysphagia (Side Effect) and Dysphagia (Side Effect) is caused by Levofloxacin (Compound)
Perphenazine (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Enoxacin (Compound) and Enoxacin (Compound) resembles Levofloxacin (Compound)
Perphenazine (Compound) causes Dysphagia (Side Effect) and Dysphagia (Side Effect) is caused by Ciprofloxacin (Compound) and Ciprofloxacin (Compound) resembles Levofloxacin (Compound)
Perphenazine (Compound) causes Hyperkinesia (Side Effect) and Hyperkinesia (Side Effect) is caused by Sparfloxacin (Compound) and Sparfloxacin (Compound) resembles Levofloxacin (Compound)
Perphenazine (Compound) resembles Triflupromazine (Compound) and Triflupromazine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Levofloxacin (Compound)
Perphenazine (Compound) resembles Hydroxyzine (Compound) and Hydroxyzine (Compound) causes Drowsiness (Side Effect) and Drowsiness (Side Effect) is caused by Levofloxacin (Compound)
Perphenazine (Compound) resembles Propericiazine (Compound) and Propericiazine (Compound) causes Aggression (Side Effect) and Aggression (Side Effect) is caused by Levofloxacin (Compound)
Perphenazine (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is associated with chronic obstructive pulmonary disease (Disease) and chronic obstructive pulmonary disease (Disease) is palliated by Levofloxacin (Compound)
Perphenazine (Compound) resembles Ethopropazine (Compound) and Ethopropazine (Compound) upregulates GPATCH8 (Gene) and GPATCH8 (Gene) is upregulated by Levofloxacin (Compound)