DDInter1826 DDInter809
A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. It was first introduced by Bristol-Myers Squibb in 1999 under the brand name Tequin® for the treatment of respiratory tract infections. Gatifloxacin is available as tablets and in various aqueous solutions for intravenous therapy. It is also available as eye drops under the brand name Zymar® marketed by Allergan. The FDA withdrew its approval for the use of non-ophthalmic drug products containing gatifloxacin due to the high prevalence of gatifloxacin-associated dysglycemia adverse event reports and the high incidence of hyperglycemic and hypoglycemic episodes in patients taking gatifloxacin compared to those on macrolide antibiotics.[L43942,L44037]
Tolazamide {u} (Compound) downregulates {v} (Gene) GDF15
GDF15 {u} (Gene) is downregulated by {v} (Compound) Gatifloxacin
Tolazamide {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Gatifloxacin
Tolazamide {u} (Compound) resembles {v} (Compound) Tolbutamide
Tolbutamide {u} may lead to a major life threatening interaction when taken with {v} Gatifloxacin
Tolazamide {u} (Compound) downregulates {v} (Gene) GDF15
GDF15 {u} (Gene) is regulated by {v} (Gene) SSBP2
SSBP2 {u} (Gene) is upregulated by {v} (Compound) Gatifloxacin
Tolazamide {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Lomefloxacin
Lomefloxacin {u} (Compound) resembles {v} (Compound) Gatifloxacin
Tolazamide {u} (Compound) causes {v} (Side Effect) Alcohol intolerance
Alcohol intolerance {u} (Side Effect) is caused by {v} (Compound) Tolbutamide
Tolbutamide {u} may lead to a major life threatening interaction when taken with {v} Gatifloxacin
Tolazamide {u} (Compound) resembles {v} (Compound) Tolbutamide
Tolbutamide {u} may lead to a major life threatening interaction when taken with {v} Lomefloxacin
Lomefloxacin {u} (Compound) resembles {v} (Compound) Gatifloxacin
Tolazamide {u} (Compound) resembles {v} (Compound) Sulfacetamide
Sulfacetamide {u} (Compound) resembles {v} (Compound) Tolbutamide
Tolbutamide {u} may lead to a major life threatening interaction when taken with {v} Gatifloxacin
Tolazamide {u} (Compound) causes {v} (Side Effect) Alcohol intolerance
Alcohol intolerance {u} (Side Effect) is caused by {v} (Compound) Glimepiride
Glimepiride {u} may lead to a major life threatening interaction when taken with {v} Gatifloxacin
Tolazamide {u} (Compound) resembles {v} (Compound) Glisoxepide
Glisoxepide {u} (Compound) resembles {v} (Compound) Glimepiride
Glimepiride {u} may lead to a major life threatening interaction when taken with {v} Gatifloxacin
Tolazamide (Compound) downregulates GDF15 (Gene) and GDF15 (Gene) is downregulated by Gatifloxacin (Compound)
Tolazamide (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Gatifloxacin (Compound)
Tolazamide (Compound) resembles Tolbutamide (Compound) and Tolbutamide may lead to a major life threatening interaction when taken with Gatifloxacin
Tolazamide (Compound) downregulates GDF15 (Gene) and GDF15 (Gene) is regulated by SSBP2 (Gene) and SSBP2 (Gene) is upregulated by Gatifloxacin (Compound)
Tolazamide (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Lomefloxacin (Compound) and Lomefloxacin (Compound) resembles Gatifloxacin (Compound)
Tolazamide (Compound) causes Alcohol intolerance (Side Effect) and Alcohol intolerance (Side Effect) is caused by Tolbutamide (Compound) and Tolbutamide may lead to a major life threatening interaction when taken with Gatifloxacin
Tolazamide (Compound) resembles Tolbutamide (Compound) and Tolbutamide may lead to a major life threatening interaction when taken with Lomefloxacin and Lomefloxacin (Compound) resembles Gatifloxacin (Compound)
Tolazamide (Compound) resembles Sulfacetamide (Compound) and Sulfacetamide (Compound) resembles Tolbutamide (Compound) and Tolbutamide may lead to a major life threatening interaction when taken with Gatifloxacin
Tolazamide (Compound) causes Alcohol intolerance (Side Effect) and Alcohol intolerance (Side Effect) is caused by Glimepiride (Compound) and Glimepiride may lead to a major life threatening interaction when taken with Gatifloxacin
Tolazamide (Compound) resembles Glisoxepide (Compound) and Glisoxepide (Compound) resembles Glimepiride (Compound) and Glimepiride may lead to a major life threatening interaction when taken with Gatifloxacin