DDInter1259 DDInter904
Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Nalidixic acid {u} (Compound) downregulates {v} (Gene) HTATSF1
HTATSF1 {u} (Gene) is upregulated by {v} (Compound) Idarubicin
Nalidixic acid {u} (Compound) upregulates {v} (Gene) HERC6
HERC6 {u} (Gene) is upregulated by {v} (Compound) Idarubicin
Nalidixic acid {u} (Compound) causes {v} (Side Effect) Gastrointestinal pain
Gastrointestinal pain {u} (Side Effect) is caused by {v} (Compound) Idarubicin
Nalidixic acid {u} (Compound) resembles {v} (Compound) Enoxacin
Enoxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Idarubicin
Nalidixic acid {u} (Compound) resembles {v} (Compound) Norfloxacin
Norfloxacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Idarubicin
Nalidixic acid {u} (Compound) downregulates {v} (Gene) HTATSF1
HTATSF1 {u} (Gene) is regulated by {v} (Gene) SOX2
SOX2 {u} (Gene) is upregulated by {v} (Compound) Idarubicin
Nalidixic acid {u} (Compound) upregulates {v} (Gene) HERC6
HERC6 {u} (Gene) is upregulated by {v} (Compound) Doxorubicin
Doxorubicin {u} (Compound) resembles {v} (Compound) Idarubicin
Nalidixic acid {u} (Compound) causes {v} (Side Effect) Gastrointestinal pain
Gastrointestinal pain {u} (Side Effect) is caused by {v} (Compound) Valrubicin
Valrubicin {u} (Compound) resembles {v} (Compound) Idarubicin
Nalidixic acid {u} (Compound) resembles {v} (Compound) Enoxacin
Enoxacin {u} (Compound) upregulates {v} (Gene) HERC6
HERC6 {u} (Gene) is upregulated by {v} (Compound) Idarubicin
Nalidixic acid {u} (Compound) resembles {v} (Compound) Lomefloxacin
Lomefloxacin {u} (Compound) causes {v} (Side Effect) Chills
Chills {u} (Side Effect) is caused by {v} (Compound) Idarubicin
Nalidixic acid (Compound) downregulates HTATSF1 (Gene) and HTATSF1 (Gene) is upregulated by Idarubicin (Compound)
Nalidixic acid (Compound) upregulates HERC6 (Gene) and HERC6 (Gene) is upregulated by Idarubicin (Compound)
Nalidixic acid (Compound) causes Gastrointestinal pain (Side Effect) and Gastrointestinal pain (Side Effect) is caused by Idarubicin (Compound)
Nalidixic acid (Compound) resembles Enoxacin (Compound) and Enoxacin may cause a minor interaction that can limit clinical effects when taken with Idarubicin
Nalidixic acid (Compound) resembles Norfloxacin (Compound) and Norfloxacin may cause a moderate interaction that could exacerbate diseases when taken with Idarubicin
Nalidixic acid (Compound) downregulates HTATSF1 (Gene) and HTATSF1 (Gene) is regulated by SOX2 (Gene) and SOX2 (Gene) is upregulated by Idarubicin (Compound)
Nalidixic acid (Compound) upregulates HERC6 (Gene) and HERC6 (Gene) is upregulated by Doxorubicin (Compound) and Doxorubicin (Compound) resembles Idarubicin (Compound)
Nalidixic acid (Compound) causes Gastrointestinal pain (Side Effect) and Gastrointestinal pain (Side Effect) is caused by Valrubicin (Compound) and Valrubicin (Compound) resembles Idarubicin (Compound)
Nalidixic acid (Compound) resembles Enoxacin (Compound) and Enoxacin (Compound) upregulates HERC6 (Gene) and HERC6 (Gene) is upregulated by Idarubicin (Compound)
Nalidixic acid (Compound) resembles Lomefloxacin (Compound) and Lomefloxacin (Compound) causes Chills (Side Effect) and Chills (Side Effect) is caused by Idarubicin (Compound)