DDInter38 DDInter957
Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon for this amino acid was deleted during the genetic engineering procedure; c) the molecule has serine substituted for cysteine at amino acid position 125.
Iodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.
Aldesleukin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Losartan
Losartan {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Aldesleukin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Losartan
Losartan {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Aldesleukin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fluorouracil
Fluorouracil {u} (Compound) downregulates {v} (Gene) GRB7
GRB7 {u} (Gene) is downregulated by {v} (Compound) Iodipamide
Aldesleukin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Gatifloxacin
Gatifloxacin {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Aldesleukin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Gatifloxacin
Gatifloxacin {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Aldesleukin {u} may lead to a major life threatening interaction when taken with {v} Iohexol
Iohexol {u} (Compound) is included by {v} (Pharmacologic Class) X-Ray Contrast Activity
X-Ray Contrast Activity {u} (Pharmacologic Class) includes {v} (Compound) Iodipamide
Aldesleukin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iodixanol
Iodixanol {u} (Compound) is included by {v} (Pharmacologic Class) X-Ray Contrast Activity
X-Ray Contrast Activity {u} (Pharmacologic Class) includes {v} (Compound) Iodipamide
Aldesleukin {u} may lead to a major life threatening interaction when taken with {v} Iohexol
Iohexol {u} (Compound) downregulates {v} (Gene) NVL
NVL {u} (Gene) is downregulated by {v} (Compound) Iodipamide
Aldesleukin {u} may lead to a major life threatening interaction when taken with {v} Iohexol
Iohexol {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Aldesleukin may cause a moderate interaction that could exacerbate diseases when taken with Losartan and Losartan (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Aldesleukin may cause a moderate interaction that could exacerbate diseases when taken with Losartan and Losartan (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Iodipamide (Compound)
Aldesleukin may cause a moderate interaction that could exacerbate diseases when taken with Fluorouracil and Fluorouracil (Compound) downregulates GRB7 (Gene) and GRB7 (Gene) is downregulated by Iodipamide (Compound)
Aldesleukin may cause a minor interaction that can limit clinical effects when taken with Gatifloxacin and Gatifloxacin (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Aldesleukin may cause a minor interaction that can limit clinical effects when taken with Gatifloxacin and Gatifloxacin (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Iodipamide (Compound)
Aldesleukin may lead to a major life threatening interaction when taken with Iohexol and Iohexol (Compound) is included by X-Ray Contrast Activity (Pharmacologic Class) and X-Ray Contrast Activity (Pharmacologic Class) includes Iodipamide (Compound)
Aldesleukin may cause a moderate interaction that could exacerbate diseases when taken with Iodixanol and Iodixanol (Compound) is included by X-Ray Contrast Activity (Pharmacologic Class) and X-Ray Contrast Activity (Pharmacologic Class) includes Iodipamide (Compound)
Aldesleukin may lead to a major life threatening interaction when taken with Iohexol and Iohexol (Compound) downregulates NVL (Gene) and NVL (Gene) is downregulated by Iodipamide (Compound)
Aldesleukin may lead to a major life threatening interaction when taken with Iohexol and Iohexol (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Iodipamide (Compound)