DDInter534 DDInter1441
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome. (From Martindale, The Extra Pharmacopoeia, 30th ed, p589) Given diazepam's storied history as a commonly used and effective medication for a variety of indications, contemporary advancements in the formulation and administration of the agent include the development and US FDA approval of an auto-injectable formulation for the rapid treatment of uncontrolled seizures in 2015-2016. Combining diazepam, a proven effective therapy for acute repetitive seizures
Phenindamine is an antihistamine. Phenindamine blocks the effects of the naturally occurring chemical histamine in your body. Antihistamines such as phenindamine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release. It is used to treat sneezing, runny nose, itching, watery eyes, hives, rashes, itching, and other symptoms of allergies and the common cold. Symptoms of a phenindamine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures.
Diazepam {u} (Compound) resembles {v} (Compound) Oxcarbazepine
Oxcarbazepine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenindamine
Diazepam {u} (Compound) resembles {v} (Compound) Oxazepam
Oxazepam {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenindamine
Diazepam {u} (Compound) resembles {v} (Compound) Oxcarbazepine
Oxcarbazepine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cyclizine
Cyclizine {u} (Compound) resembles {v} (Compound) Phenindamine
Diazepam {u} (Compound) resembles {v} (Compound) Oxazepam
Oxazepam {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Azatadine
Azatadine {u} (Compound) resembles {v} (Compound) Phenindamine
Diazepam {u} (Compound) resembles {v} (Compound) Alprazolam
Alprazolam {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Azatadine
Azatadine {u} (Compound) resembles {v} (Compound) Phenindamine
Diazepam {u} (Compound) binds {v} (Gene) CYP2C9
CYP2C9 {u} (Gene) is bound by {v} (Compound) Mirtazapine
Mirtazapine {u} (Compound) resembles {v} (Compound) Phenindamine
Diazepam {u} (Compound) resembles {v} (Compound) Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cyclizine
Cyclizine {u} (Compound) resembles {v} (Compound) Phenindamine
Diazepam {u} (Compound) resembles {v} (Compound) Oxcarbazepine
Oxcarbazepine {u} (Compound) resembles {v} (Compound) Nortriptyline
Nortriptyline {u} (Compound) resembles {v} (Compound) Phenindamine
Diazepam {u} (Compound) resembles {v} (Compound) Oxazepam
Oxazepam {u} (Compound) resembles {v} (Compound) Phenindione
Phenindione {u} (Compound) resembles {v} (Compound) Phenindamine
Diazepam {u} (Compound) resembles {v} (Compound) Clomipramine
Clomipramine {u} (Compound) resembles {v} (Compound) Nortriptyline
Nortriptyline {u} (Compound) resembles {v} (Compound) Phenindamine
Diazepam (Compound) resembles Oxcarbazepine (Compound) and Oxcarbazepine may cause a moderate interaction that could exacerbate diseases when taken with Phenindamine
Diazepam (Compound) resembles Oxazepam (Compound) and Oxazepam may cause a moderate interaction that could exacerbate diseases when taken with Phenindamine
Diazepam (Compound) resembles Oxcarbazepine (Compound) and Oxcarbazepine may cause a moderate interaction that could exacerbate diseases when taken with Cyclizine and Cyclizine (Compound) resembles Phenindamine (Compound)
Diazepam (Compound) resembles Oxazepam (Compound) and Oxazepam may cause a moderate interaction that could exacerbate diseases when taken with Azatadine and Azatadine (Compound) resembles Phenindamine (Compound)
Diazepam (Compound) resembles Alprazolam (Compound) and Alprazolam may cause a moderate interaction that could exacerbate diseases when taken with Azatadine and Azatadine (Compound) resembles Phenindamine (Compound)
Diazepam (Compound) binds CYP2C9 (Gene) and CYP2C9 (Gene) is bound by Mirtazapine (Compound) and Mirtazapine (Compound) resembles Phenindamine (Compound)
Diazepam (Compound) resembles Loxapine (Compound) and Loxapine (Compound) resembles Cyclizine (Compound) and Loxapine may cause a moderate interaction that could exacerbate diseases when taken with Cyclizine and Cyclizine (Compound) resembles Phenindamine (Compound)
Diazepam (Compound) resembles Oxcarbazepine (Compound) and Oxcarbazepine (Compound) resembles Nortriptyline (Compound) and Nortriptyline (Compound) resembles Phenindamine (Compound)
Diazepam (Compound) resembles Oxazepam (Compound) and Oxazepam (Compound) resembles Phenindione (Compound) and Phenindione (Compound) resembles Phenindamine (Compound)
Diazepam (Compound) resembles Clomipramine (Compound) and Clomipramine (Compound) resembles Nortriptyline (Compound) and Nortriptyline (Compound) resembles Phenindamine (Compound)