DDInter405 DDInter134
Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed. It is not known if the drug extends life expectancy. Its potential use in acute myeloid leukaemia (AML) and juvenile myelomonocytic leukaemia (JMML) has been investigated.
Atovaquone is a hydroxynaphthoquinone, or an analog of ubiquinone, that has antimicrobial and antipneumocystis activity. It is being used in antimalarial protocols.
Clofarabine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acarbose
Acarbose {u} may cause a minor interaction that can limit clinical effects when taken with {v} Anisindione
Anisindione {u} (Compound) resembles {v} (Compound) Atovaquone
Clofarabine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Simvastatin
Simvastatin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Anisindione
Anisindione {u} (Compound) resembles {v} (Compound) Atovaquone
Clofarabine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Olsalazine
Olsalazine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Anisindione
Anisindione {u} (Compound) resembles {v} (Compound) Atovaquone
Clofarabine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Simvastatin
Simvastatin {u} (Compound) binds {v} (Gene) CYP2C9
CYP2C9 {u} (Gene) is bound by {v} (Compound) Atovaquone
Clofarabine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Chenodeoxycholic acid
Chenodeoxycholic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Anisindione
Anisindione {u} (Compound) resembles {v} (Compound) Atovaquone
Clofarabine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Erlotinib
Erlotinib {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Anisindione
Anisindione {u} (Compound) resembles {v} (Compound) Atovaquone
Clofarabine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Gefitinib
Gefitinib {u} (Compound) binds {v} (Gene) CYP2C9
CYP2C9 {u} (Gene) is bound by {v} (Compound) Atovaquone
Clofarabine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mercaptopurine
Mercaptopurine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Anisindione
Anisindione {u} (Compound) resembles {v} (Compound) Atovaquone
Clofarabine {u} may lead to a major life threatening interaction when taken with {v} Teriflunomide
Teriflunomide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Anisindione
Anisindione {u} (Compound) resembles {v} (Compound) Atovaquone
Clofarabine {u} may lead to a major life threatening interaction when taken with {v} Leflunomide
Leflunomide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Anisindione
Anisindione {u} (Compound) resembles {v} (Compound) Atovaquone
Clofarabine may cause a moderate interaction that could exacerbate diseases when taken with Acarbose and Acarbose may cause a minor interaction that can limit clinical effects when taken with Anisindione and Anisindione (Compound) resembles Atovaquone (Compound)
Clofarabine may cause a moderate interaction that could exacerbate diseases when taken with Simvastatin and Simvastatin may cause a minor interaction that can limit clinical effects when taken with Anisindione and Anisindione (Compound) resembles Atovaquone (Compound)
Clofarabine may cause a moderate interaction that could exacerbate diseases when taken with Olsalazine and Olsalazine may cause a minor interaction that can limit clinical effects when taken with Anisindione and Anisindione (Compound) resembles Atovaquone (Compound)
Clofarabine may cause a moderate interaction that could exacerbate diseases when taken with Simvastatin and Simvastatin (Compound) binds CYP2C9 (Gene) and CYP2C9 (Gene) is bound by Atovaquone (Compound)
Clofarabine may cause a moderate interaction that could exacerbate diseases when taken with Chenodeoxycholic acid and Chenodeoxycholic acid may cause a moderate interaction that could exacerbate diseases when taken with Anisindione and Anisindione (Compound) resembles Atovaquone (Compound)
Clofarabine may cause a moderate interaction that could exacerbate diseases when taken with Erlotinib and Erlotinib may cause a moderate interaction that could exacerbate diseases when taken with Anisindione and Anisindione (Compound) resembles Atovaquone (Compound)
Clofarabine may cause a moderate interaction that could exacerbate diseases when taken with Gefitinib and Gefitinib (Compound) binds CYP2C9 (Gene) and CYP2C9 (Gene) is bound by Atovaquone (Compound)
Clofarabine may cause a moderate interaction that could exacerbate diseases when taken with Mercaptopurine and Mercaptopurine may cause a moderate interaction that could exacerbate diseases when taken with Anisindione and Anisindione (Compound) resembles Atovaquone (Compound)
Clofarabine may lead to a major life threatening interaction when taken with Teriflunomide and Teriflunomide may cause a moderate interaction that could exacerbate diseases when taken with Anisindione and Anisindione (Compound) resembles Atovaquone (Compound)
Clofarabine may lead to a major life threatening interaction when taken with Leflunomide and Leflunomide may cause a moderate interaction that could exacerbate diseases when taken with Anisindione and Anisindione (Compound) resembles Atovaquone (Compound)