DDInter1553 DDInter1016
Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as [clozapine] and [olanzapine].
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose]. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. [sucrose]). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in patients with cirrhosis.[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.
Quetiapine {u} (Compound) resembles {v} (Compound) Trazodone
Quetiapine {u} (Compound) binds {v} (Gene) DRD5
Quetiapine {u} (Compound) upregulates {v} (Gene) SLC11A2
Quetiapine {u} (Compound) palliates {v} (Disease) autistic disorder
Quetiapine {u} (Compound) downregulates {v} (Gene) TM9SF2
Quetiapine {u} (Compound) causes {v} (Side Effect) Salivary hypersecretion
Quetiapine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metronidazole
Quetiapine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sitagliptin
Quetiapine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Diphenhydramine
Quetiapine {u} may lead to a major life threatening interaction when taken with {v} Clarithromycin
Quetiapine (Compound) resembles Trazodone (Compound)
Quetiapine (Compound) binds DRD5 (Gene)
Quetiapine (Compound) upregulates SLC11A2 (Gene)
Quetiapine (Compound) palliates autistic disorder (Disease)
Quetiapine (Compound) downregulates TM9SF2 (Gene)
Quetiapine (Compound) causes Salivary hypersecretion (Side Effect)
Quetiapine may cause a minor interaction that can limit clinical effects when taken with Metronidazole
Quetiapine may cause a moderate interaction that could exacerbate diseases when taken with Sitagliptin
Quetiapine may cause a moderate interaction that could exacerbate diseases when taken with Diphenhydramine
Quetiapine may lead to a major life threatening interaction when taken with Clarithromycin