DDInter790 DDInter1783
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of water from the body. Furosemide has a fast onset and short duration of action and has been used safely and effectively in both pediatric and adult patients. The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential. In addition to oral formulations, the solution for intravenous and intramuscular administration is also available, which is typically limited to patients who are unable to take oral medication or for patients in emergency clinical situations.
Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the bacterial 50S ribosomal subunit and may alter the cytoplasmic membrane causing intracellular components to leak from bacterial cells. The FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml. Other formulations of tetracycline continue to be used.
Furosemide {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Tetracycline
Furosemide {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Tetracycline
Furosemide {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Methacycline
Methacycline {u} (Compound) resembles {v} (Compound) Tetracycline
Furosemide {u} (Compound) palliates {v} (Disease) chronic kidney failure
chronic kidney failure {u} (Disease) is associated with {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Tetracycline
Furosemide {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Doxycycline
Doxycycline {u} (Compound) resembles {v} (Compound) Tetracycline
Furosemide {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Etacrynic acid
Etacrynic acid {u} may cause a minor interaction that can limit clinical effects when taken with {v} Tetracycline
Furosemide {u} (Compound) treats {v} (Disease) coronary artery disease
coronary artery disease {u} (Disease) is associated with {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Tetracycline
Furosemide {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Mycophenolate mofetil
Mycophenolate mofetil {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tetracycline
Furosemide {u} (Compound) treats {v} (Disease) coronary artery disease
coronary artery disease {u} (Disease) is palliated by {v} (Compound) Digoxin
Digoxin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tetracycline
Furosemide {u} (Compound) palliates {v} (Disease) chronic kidney failure
chronic kidney failure {u} (Disease) is palliated by {v} (Compound) Torasemide
Torasemide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Tetracycline
Furosemide (Compound) binds ALB (Gene) and ALB (Gene) is bound by Tetracycline (Compound)
Furosemide (Compound) resembles Indapamide (Compound) and Indapamide may cause a minor interaction that can limit clinical effects when taken with Tetracycline
Furosemide (Compound) binds ALB (Gene) and ALB (Gene) is bound by Methacycline (Compound) and Methacycline (Compound) resembles Tetracycline (Compound)
Furosemide (Compound) palliates chronic kidney failure (Disease) and chronic kidney failure (Disease) is associated with ALB (Gene) and ALB (Gene) is bound by Tetracycline (Compound)
Furosemide (Compound) resembles Indapamide (Compound) and Indapamide may cause a minor interaction that can limit clinical effects when taken with Doxycycline and Doxycycline (Compound) resembles Tetracycline (Compound)
Furosemide (Compound) binds ALB (Gene) and ALB (Gene) is bound by Etacrynic acid (Compound) and Etacrynic acid may cause a minor interaction that can limit clinical effects when taken with Tetracycline
Furosemide (Compound) treats coronary artery disease (Disease) and coronary artery disease (Disease) is associated with ALB (Gene) and ALB (Gene) is bound by Tetracycline (Compound)
Furosemide (Compound) binds ALB (Gene) and ALB (Gene) is bound by Mycophenolate mofetil (Compound) and Mycophenolate mofetil may cause a moderate interaction that could exacerbate diseases when taken with Tetracycline
Furosemide (Compound) treats coronary artery disease (Disease) and coronary artery disease (Disease) is palliated by Digoxin (Compound) and Digoxin may cause a moderate interaction that could exacerbate diseases when taken with Tetracycline
Furosemide (Compound) palliates chronic kidney failure (Disease) and chronic kidney failure (Disease) is palliated by Torasemide (Compound) and Torasemide may cause a minor interaction that can limit clinical effects when taken with Tetracycline