DDInter89 DDInter1174
Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and non-Hodgkin's lymphoma.[A180322,L7144,L7147,L7150,L7180] Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and severe psoriasis only if first line treatment has failed or patients are intolerant of those treatments. Methotrexate was granted FDA approval on 7 December 1953.
Ampicillin {u} (Compound) binds {v} (Gene) SLC16A1
SLC16A1 {u} (Gene) is bound by {v} (Compound) Methotrexate
Ampicillin {u} (Compound) causes {v} (Side Effect) Anaemia
Anaemia {u} (Side Effect) is caused by {v} (Compound) Methotrexate
Ampicillin {u} (Compound) resembles {v} (Compound) Carbenicillin
Carbenicillin {u} may lead to a major life threatening interaction when taken with {v} Methotrexate
Ampicillin {u} (Compound) resembles {v} (Compound) Nafcillin
Nafcillin {u} may lead to a major life threatening interaction when taken with {v} Methotrexate
Ampicillin {u} (Compound) resembles {v} (Compound) Dicloxacillin
Dicloxacillin {u} may lead to a major life threatening interaction when taken with {v} Methotrexate
Ampicillin {u} (Compound) binds {v} (Gene) SLC16A1
SLC16A1 {u} (Gene) regulates {v} (Gene) TYMS
TYMS {u} (Gene) is bound by {v} (Compound) Methotrexate
Ampicillin {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is associated with {v} (Disease) stomach cancer
stomach cancer {u} (Disease) is treated by {v} (Compound) Methotrexate
Ampicillin {u} (Compound) causes {v} (Side Effect) Anaemia
Anaemia {u} (Side Effect) is caused by {v} (Compound) Raltitrexed
Raltitrexed {u} (Compound) resembles {v} (Compound) Methotrexate
Ampicillin {u} (Compound) causes {v} (Side Effect) Glossitis
Glossitis {u} (Side Effect) is caused by {v} (Compound) Lamotrigine
Lamotrigine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Methotrexate
Ampicillin {u} (Compound) causes {v} (Side Effect) Dermatitis exfoliative
Dermatitis exfoliative {u} (Side Effect) is caused by {v} (Compound) Hydroxychloroquine
Hydroxychloroquine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Methotrexate
Ampicillin (Compound) binds SLC16A1 (Gene) and SLC16A1 (Gene) is bound by Methotrexate (Compound)
Ampicillin (Compound) causes Anaemia (Side Effect) and Anaemia (Side Effect) is caused by Methotrexate (Compound)
Ampicillin (Compound) resembles Carbenicillin (Compound) and Carbenicillin may lead to a major life threatening interaction when taken with Methotrexate
Ampicillin (Compound) resembles Nafcillin (Compound) and Nafcillin may lead to a major life threatening interaction when taken with Methotrexate
Ampicillin (Compound) resembles Dicloxacillin (Compound) and Dicloxacillin may lead to a major life threatening interaction when taken with Methotrexate
Ampicillin (Compound) binds SLC16A1 (Gene) and SLC16A1 (Gene) regulates TYMS (Gene) and TYMS (Gene) is bound by Methotrexate (Compound)
Ampicillin (Compound) binds ALB (Gene) and ALB (Gene) is associated with stomach cancer (Disease) and stomach cancer (Disease) is treated by Methotrexate (Compound)
Ampicillin (Compound) causes Anaemia (Side Effect) and Anaemia (Side Effect) is caused by Raltitrexed (Compound) and Raltitrexed (Compound) resembles Methotrexate (Compound)
Ampicillin (Compound) causes Glossitis (Side Effect) and Glossitis (Side Effect) is caused by Lamotrigine (Compound) and Lamotrigine may cause a minor interaction that can limit clinical effects when taken with Methotrexate
Ampicillin (Compound) causes Dermatitis exfoliative (Side Effect) and Dermatitis exfoliative (Side Effect) is caused by Hydroxychloroquine (Compound) and Hydroxychloroquine may cause a minor interaction that can limit clinical effects when taken with Methotrexate