DDInter687 DDInter534
Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1. Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids. It is used to treat or manage a variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and juvenile idiopathic poly-articular arthritis (JIA).
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome. (From Martindale, The Extra Pharmacopoeia, 30th ed, p589) Given diazepam's storied history as a commonly used and effective medication for a variety of indications, contemporary advancements in the formulation and administration of the agent include the development and US FDA approval of an auto-injectable formulation for the rapid treatment of uncontrolled seizures in 2015-2016 . Combining diazepam, a proven effective therapy for acute repetitive seizures, with an auto-injector designed for subcutaneous administration that is quickly and easily administered offers the potential for complete, consistent drug absorption and rapid onset of effect . This current development is subsequently an important addition to the rescue therapy tool chest for patients with epilepsy .
Etanercept {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clonazepam
Clonazepam {u} (Compound) resembles {v} (Compound) Diazepam
Etanercept {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clobazam
Clobazam {u} (Compound) resembles {v} (Compound) Diazepam
Etanercept {u} may lead to a major life threatening interaction when taken with {v} Clozapine
Clozapine {u} (Compound) resembles {v} (Compound) Diazepam
Etanercept {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clonazepam
Clonazepam {u} (Compound) resembles {v} (Compound) Quazepam
Quazepam {u} (Compound) resembles {v} (Compound) Diazepam
Etanercept {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clobazam
Clobazam {u} (Compound) resembles {v} (Compound) Oxazepam
Oxazepam {u} (Compound) resembles {v} (Compound) Diazepam
Etanercept {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ethionamide
Ethionamide {u} (Compound) causes {v} (Side Effect) Dermatitis
Dermatitis {u} (Side Effect) is caused by {v} (Compound) Diazepam
Etanercept {u} may lead to a major life threatening interaction when taken with {v} Clozapine
Clozapine {u} (Compound) resembles {v} (Compound) Oxazepam
Oxazepam {u} (Compound) resembles {v} (Compound) Diazepam
Etanercept {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clonazepam
Clonazepam {u} (Compound) resembles {v} (Compound) Oxazepam
Oxazepam {u} (Compound) resembles {v} (Compound) Diazepam
Etanercept {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Etravirine
Etravirine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Diazepam
Etanercept {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Etravirine
Etravirine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Flurbiprofen
Flurbiprofen {u} (Compound) resembles {v} (Compound) Diazepam
Etanercept may cause a moderate interaction that could exacerbate diseases when taken with Clonazepam and Clonazepam (Compound) resembles Diazepam (Compound)
Etanercept may cause a moderate interaction that could exacerbate diseases when taken with Clobazam and Clobazam (Compound) resembles Diazepam (Compound)
Etanercept may lead to a major life threatening interaction when taken with Clozapine and Clozapine (Compound) resembles Diazepam (Compound)
Etanercept may cause a moderate interaction that could exacerbate diseases when taken with Clonazepam and Clonazepam (Compound) resembles Quazepam (Compound) and Quazepam (Compound) resembles Diazepam (Compound)
Etanercept may cause a moderate interaction that could exacerbate diseases when taken with Clobazam and Clobazam (Compound) resembles Oxazepam (Compound) and Oxazepam (Compound) resembles Diazepam (Compound)
Etanercept may cause a moderate interaction that could exacerbate diseases when taken with Ethionamide and Ethionamide (Compound) causes Dermatitis (Side Effect) and Dermatitis (Side Effect) is caused by Diazepam (Compound)
Etanercept may lead to a major life threatening interaction when taken with Clozapine and Clozapine (Compound) resembles Oxazepam (Compound) and Oxazepam (Compound) resembles Diazepam (Compound)
Etanercept may cause a moderate interaction that could exacerbate diseases when taken with Clonazepam and Clonazepam (Compound) resembles Oxazepam (Compound) and Oxazepam (Compound) resembles Diazepam (Compound)
Etanercept may cause a moderate interaction that could exacerbate diseases when taken with Etravirine and Etravirine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Diazepam (Compound)
Etanercept may cause a moderate interaction that could exacerbate diseases when taken with Etravirine and Etravirine may cause a moderate interaction that could exacerbate diseases when taken with Flurbiprofen and Flurbiprofen (Compound) resembles Diazepam (Compound)