DDInter1936 DDInter1652
Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)
Secukinumab is a fully human monoclonal IgG1/κ antibody against interleukin-17A (IL-17A), a proinflammatory cytokine implicated in various chronic immune-mediated inflammatory disorders, such as plaque psoriasis. By blocking the actions of IL-17A, secukinumab works to inhibit the pro-inflammatory pathways that drive immune-mediated inflammatory disorders. Following its first global approval in Japan in December 2014, secukinumab was approved by the European Commission on January 15, 2015, and by the FDA a few days after (January 21, 2015). It is currently approved to treat a number of chronic inflammatory conditions, such as plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, and hidradenitis suppurativa.[L39600,L42280,L48771]
Vinblastine {u} (Compound) resembles {v} (Compound) Vindesine
Vinblastine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Vinorelbine
Vinblastine {u} (Compound) treats {v} (Disease) kidney cancer
Vinblastine {u} (Compound) binds {v} (Gene) TUBB3
Vinblastine {u} (Compound) upregulates {v} (Gene) OSBPL2
Vinblastine {u} (Compound) is included by {v} (Pharmacologic Class) Vinca Alkaloids
Vinblastine {u} (Compound) downregulates {v} (Gene) TMEM168
Vinblastine {u} (Compound) causes {v} (Side Effect) Paraesthesia
Vinblastine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Lomefloxacin
Vinblastine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Fluorouracil
Vinblastine (Compound) resembles Vindesine (Compound)
Vinblastine may cause a moderate interaction that could exacerbate diseases when taken with Vinorelbine
Vinblastine (Compound) treats kidney cancer (Disease)
Vinblastine (Compound) binds TUBB3 (Gene)
Vinblastine (Compound) upregulates OSBPL2 (Gene)
Vinblastine (Compound) is included by Vinca Alkaloids (Pharmacologic Class)
Vinblastine (Compound) downregulates TMEM168 (Gene)
Vinblastine (Compound) causes Paraesthesia (Side Effect)
Vinblastine may cause a minor interaction that can limit clinical effects when taken with Lomefloxacin
Vinblastine may cause a minor interaction that can limit clinical effects when taken with Fluorouracil