DDInter118 DDInter1180
Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and antagonism of alpha-adrenergic and 5-HT2A receptors.[L45859,A4393] Aripiprazole was given FDA approval on November 15, 2002.
Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Aripiprazole {u} (Compound) resembles {v} (Compound) Nefazodone
Aripiprazole {u} (Compound) resembles {v} (Compound) Trazodone
Aripiprazole {u} (Compound) binds {v} (Gene) ADRA1B
Aripiprazole {u} (Compound) upregulates {v} (Gene) AARS
Aripiprazole {u} (Compound) palliates {v} (Disease) bipolar disorder
Aripiprazole {u} (Compound) downregulates {v} (Gene) PCNA
Aripiprazole {u} (Compound) causes {v} (Side Effect) Orthostatic hypotension
Aripiprazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metronidazole
Aripiprazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Abarelix
Aripiprazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Triclabendazole
Aripiprazole (Compound) resembles Nefazodone (Compound)
Aripiprazole (Compound) resembles Trazodone (Compound)
Aripiprazole (Compound) binds ADRA1B (Gene)
Aripiprazole (Compound) upregulates AARS (Gene)
Aripiprazole (Compound) palliates bipolar disorder (Disease)
Aripiprazole (Compound) downregulates PCNA (Gene)
Aripiprazole (Compound) causes Orthostatic hypotension (Side Effect)
Aripiprazole may cause a minor interaction that can limit clinical effects when taken with Metronidazole
Aripiprazole may cause a moderate interaction that could exacerbate diseases when taken with Abarelix
Aripiprazole may cause a moderate interaction that could exacerbate diseases when taken with Triclabendazole