DDInter298 DDInter906
Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma. Early clinical studies of carboplatin were performed in 1982. Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.
Ifosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppressive agent.
Carboplatin {u} (Compound) treats {v} (Disease) testicular cancer
testicular cancer {u} (Disease) is treated by {v} (Compound) Ifosfamide
Carboplatin {u} (Compound) causes {v} (Side Effect) Extravasation
Extravasation {u} (Side Effect) is caused by {v} (Compound) Ifosfamide
Carboplatin {u} (Compound) treats {v} (Disease) testicular cancer
testicular cancer {u} (Disease) resembles {v} (Disease) germ cell cancer
germ cell cancer {u} (Disease) is treated by {v} (Compound) Ifosfamide
Carboplatin {u} (Compound) causes {v} (Side Effect) Extravasation
Extravasation {u} (Side Effect) is caused by {v} (Compound) Radium Ra 223 dichloride
Radium Ra 223 dichloride {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ifosfamide
Carboplatin {u} (Compound) causes {v} (Side Effect) Phlebitis
Phlebitis {u} (Side Effect) is caused by {v} (Compound) Moxifloxacin
Moxifloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ifosfamide
Carboplatin {u} (Compound) treats {v} (Disease) esophageal cancer
esophageal cancer {u} (Disease) is treated by {v} (Compound) Cisplatin
Cisplatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ifosfamide
Carboplatin {u} (Compound) causes {v} (Side Effect) Extravasation
Extravasation {u} (Side Effect) is caused by {v} (Compound) Promethazine
Promethazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ifosfamide
Carboplatin {u} (Compound) treats {v} (Disease) esophageal cancer
esophageal cancer {u} (Disease) is associated with {v} (Gene) CYP2A6
CYP2A6 {u} (Gene) is bound by {v} (Compound) Ifosfamide
Carboplatin {u} (Compound) treats {v} (Disease) ovarian cancer
ovarian cancer {u} (Disease) resembles {v} (Disease) testicular cancer
testicular cancer {u} (Disease) is treated by {v} (Compound) Ifosfamide
Carboplatin {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Sparfloxacin
Sparfloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ifosfamide
Carboplatin (Compound) treats testicular cancer (Disease) and testicular cancer (Disease) is treated by Ifosfamide (Compound)
Carboplatin (Compound) causes Extravasation (Side Effect) and Extravasation (Side Effect) is caused by Ifosfamide (Compound)
Carboplatin (Compound) treats testicular cancer (Disease) and testicular cancer (Disease) resembles germ cell cancer (Disease) and germ cell cancer (Disease) is treated by Ifosfamide (Compound)
Carboplatin (Compound) causes Extravasation (Side Effect) and Extravasation (Side Effect) is caused by Radium Ra 223 dichloride (Compound) and Radium Ra 223 dichloride may cause a moderate interaction that could exacerbate diseases when taken with Ifosfamide
Carboplatin (Compound) causes Phlebitis (Side Effect) and Phlebitis (Side Effect) is caused by Moxifloxacin (Compound) and Moxifloxacin may cause a minor interaction that can limit clinical effects when taken with Ifosfamide
Carboplatin (Compound) treats esophageal cancer (Disease) and esophageal cancer (Disease) is treated by Cisplatin (Compound) and Cisplatin may cause a moderate interaction that could exacerbate diseases when taken with Ifosfamide
Carboplatin (Compound) causes Extravasation (Side Effect) and Extravasation (Side Effect) is caused by Promethazine (Compound) and Promethazine may cause a moderate interaction that could exacerbate diseases when taken with Ifosfamide
Carboplatin (Compound) treats esophageal cancer (Disease) and esophageal cancer (Disease) is associated with CYP2A6 (Gene) and CYP2A6 (Gene) is bound by Ifosfamide (Compound)
Carboplatin (Compound) treats ovarian cancer (Disease) and ovarian cancer (Disease) resembles testicular cancer (Disease) and testicular cancer (Disease) is treated by Ifosfamide (Compound)
Carboplatin (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Sparfloxacin (Compound) and Sparfloxacin may cause a minor interaction that can limit clinical effects when taken with Ifosfamide