DDInter1620 DDInter881
Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.
Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents. The action of hyaluronidase was first described in 1936, and named in 1939. Early research into hyaluronidase identified it as a "spreading factor" which allowed for increased permeability of the connective tissue. Hyaluronidase has been used in surgical settings for at least the past 60 years to improve the diffusion of local anesthetics. Hyaluronidase was first used in prescription products in the United States on 5 May 2004.
Ropivacaine {u} (Compound) resembles {v} (Compound) Mepivacaine
Mepivacaine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Hyaluronidase
Ropivacaine {u} (Compound) resembles {v} (Compound) Bupivacaine
Bupivacaine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Hyaluronidase
Ropivacaine {u} (Compound) resembles {v} (Compound) Mepivacaine
Mepivacaine {u} (Compound) resembles {v} (Compound) Bupivacaine
Bupivacaine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Hyaluronidase
Ropivacaine {u} (Compound) resembles {v} (Compound) Bupivacaine
Bupivacaine {u} (Compound) resembles {v} (Compound) Mepivacaine
Mepivacaine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Hyaluronidase
Ropivacaine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Mepyramine
Mepyramine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Hyaluronidase
Ropivacaine {u} (Compound) resembles {v} (Compound) Lidocaine
Lidocaine {u} may lead to a major life threatening interaction when taken with {v} Prilocaine
Prilocaine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Hyaluronidase
Ropivacaine {u} (Compound) resembles {v} (Compound) Mepivacaine
Mepivacaine {u} (Compound) resembles {v} (Compound) Lidocaine
Lidocaine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Hyaluronidase
Ropivacaine {u} (Compound) resembles {v} (Compound) Lidocaine
Lidocaine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Dexamethasone
Dexamethasone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Hyaluronidase
Ropivacaine {u} (Compound) is included by {v} (Pharmacologic Class) Local Anesthesia
Local Anesthesia {u} (Pharmacologic Class) includes {v} (Compound) Articaine
Articaine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Hyaluronidase
Ropivacaine {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Articaine
Articaine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Hyaluronidase
Ropivacaine (Compound) resembles Mepivacaine (Compound) and Mepivacaine may cause a minor interaction that can limit clinical effects when taken with Hyaluronidase
Ropivacaine (Compound) resembles Bupivacaine (Compound) and Bupivacaine may cause a minor interaction that can limit clinical effects when taken with Hyaluronidase
Ropivacaine (Compound) resembles Mepivacaine (Compound) and Mepivacaine (Compound) resembles Bupivacaine (Compound) and Bupivacaine may cause a minor interaction that can limit clinical effects when taken with Hyaluronidase
Ropivacaine (Compound) resembles Bupivacaine (Compound) and Bupivacaine (Compound) resembles Mepivacaine (Compound) and Mepivacaine may cause a minor interaction that can limit clinical effects when taken with Hyaluronidase
Ropivacaine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Mepyramine (Compound) and Mepyramine may cause a minor interaction that can limit clinical effects when taken with Hyaluronidase
Ropivacaine (Compound) resembles Lidocaine (Compound) and Lidocaine may lead to a major life threatening interaction when taken with Prilocaine and Prilocaine may cause a minor interaction that can limit clinical effects when taken with Hyaluronidase
Ropivacaine (Compound) resembles Mepivacaine (Compound) and Mepivacaine (Compound) resembles Lidocaine (Compound) and Lidocaine may cause a minor interaction that can limit clinical effects when taken with Hyaluronidase
Ropivacaine (Compound) resembles Lidocaine (Compound) and Lidocaine may cause a minor interaction that can limit clinical effects when taken with Dexamethasone and Dexamethasone may cause a minor interaction that can limit clinical effects when taken with Hyaluronidase
Ropivacaine (Compound) is included by Local Anesthesia (Pharmacologic Class) and Local Anesthesia (Pharmacologic Class) includes Articaine (Compound) and Articaine may cause a minor interaction that can limit clinical effects when taken with Hyaluronidase
Ropivacaine (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Articaine (Compound) and Articaine may cause a minor interaction that can limit clinical effects when taken with Hyaluronidase