DDInter154 DDInter357
Azelastine is a phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position. It has a role as a H1-receptor antagonist, an anti-allergic agent, an anti-asthmatic drug, a bronchodilator agent, a platelet aggregation inhibitor and an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. It is a member of phthalazines, a tertiary amino compound and a member of monochlorobenzenes.
A non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
Azelastine {u} (Compound) upregulates {v} (Gene) RPP38
RPP38 {u} (Gene) is upregulated by {v} (Compound) Chlormezanone
Azelastine {u} (Compound) downregulates {v} (Gene) DLD
DLD {u} (Gene) is downregulated by {v} (Compound) Chlormezanone
Azelastine {u} (Compound) resembles {v} (Compound) Clemastine
Clemastine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Chlormezanone
Azelastine {u} (Compound) upregulates {v} (Gene) RPP38
RPP38 {u} (Gene) interacts with {v} (Gene) ABL1
ABL1 {u} (Gene) is upregulated by {v} (Compound) Chlormezanone
Azelastine {u} (Compound) downregulates {v} (Gene) DLD
DLD {u} (Gene) is regulated by {v} (Gene) RPP38
RPP38 {u} (Gene) is upregulated by {v} (Compound) Chlormezanone
Azelastine {u} (Compound) upregulates {v} (Gene) MAL
MAL {u} (Gene) is regulated by {v} (Gene) RPP38
RPP38 {u} (Gene) is upregulated by {v} (Compound) Chlormezanone
Azelastine {u} (Compound) resembles {v} (Compound) Clemastine
Clemastine {u} (Compound) downregulates {v} (Gene) DLD
DLD {u} (Gene) is downregulated by {v} (Compound) Chlormezanone
Azelastine {u} (Compound) upregulates {v} (Gene) RPP38
RPP38 {u} (Gene) regulates {v} (Gene) DLD
DLD {u} (Gene) is downregulated by {v} (Compound) Chlormezanone
Azelastine {u} (Compound) resembles {v} (Compound) Clemastine
Clemastine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ifosfamide
Ifosfamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Chlormezanone
Azelastine {u} (Compound) upregulates {v} (Gene) RPP38
RPP38 {u} (Gene) is upregulated by {v} (Compound) Cyproheptadine
Cyproheptadine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Chlormezanone
Azelastine (Compound) upregulates RPP38 (Gene) and RPP38 (Gene) is upregulated by Chlormezanone (Compound)
Azelastine (Compound) downregulates DLD (Gene) and DLD (Gene) is downregulated by Chlormezanone (Compound)
Azelastine (Compound) resembles Clemastine (Compound) and Clemastine may cause a moderate interaction that could exacerbate diseases when taken with Chlormezanone
Azelastine (Compound) upregulates RPP38 (Gene) and RPP38 (Gene) interacts with ABL1 (Gene) and ABL1 (Gene) is upregulated by Chlormezanone (Compound)
Azelastine (Compound) downregulates DLD (Gene) and DLD (Gene) is regulated by RPP38 (Gene) and RPP38 (Gene) is upregulated by Chlormezanone (Compound)
Azelastine (Compound) upregulates MAL (Gene) and MAL (Gene) is regulated by RPP38 (Gene) and RPP38 (Gene) is upregulated by Chlormezanone (Compound)
Azelastine (Compound) resembles Clemastine (Compound) and Clemastine (Compound) downregulates DLD (Gene) and DLD (Gene) is downregulated by Chlormezanone (Compound)
Azelastine (Compound) upregulates RPP38 (Gene) and RPP38 (Gene) regulates DLD (Gene) and DLD (Gene) is downregulated by Chlormezanone (Compound)
Azelastine (Compound) resembles Clemastine (Compound) and Clemastine may cause a moderate interaction that could exacerbate diseases when taken with Ifosfamide and Ifosfamide may cause a moderate interaction that could exacerbate diseases when taken with Chlormezanone
Azelastine (Compound) upregulates RPP38 (Gene) and RPP38 (Gene) is upregulated by Cyproheptadine (Compound) and Cyproheptadine may cause a moderate interaction that could exacerbate diseases when taken with Chlormezanone