DDInter1397 DDInter960
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham.[L7712,L7715] A unique feature of this drug is that it is highly potent and selective in its inhibition of serotonin reuptake and has little effect on other neurotransmitters. Because of its potent inhibition of serotonin reuptake, paroxetine is more likely to cause withdrawal effects upon cessation. Paroxetine is well tolerated in most patients with a similar adverse effect profile to other members of its drug class. The controlled release formulation was designed to decrease the likelihood of nausea that is sometimes associated with paroxetine.[L7700,L7742]
Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Paroxetine {u} (Compound) downregulates {v} (Gene) PRR7
PRR7 {u} (Gene) is downregulated by {v} (Compound) Iohexol
Paroxetine {u} (Compound) causes {v} (Side Effect) Hypersensitivity
Hypersensitivity {u} (Side Effect) is caused by {v} (Compound) Iohexol
Paroxetine {u} (Compound) downregulates {v} (Gene) PRR7
PRR7 {u} (Gene) is downregulated by {v} (Compound) Trichlormethiazide
Trichlormethiazide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iohexol
Paroxetine {u} (Compound) downregulates {v} (Gene) ITGAE
ITGAE {u} (Gene) is downregulated by {v} (Compound) Iodixanol
Iodixanol {u} (Compound) resembles {v} (Compound) Iohexol
Paroxetine {u} (Compound) causes {v} (Side Effect) Hypersensitivity
Hypersensitivity {u} (Side Effect) is caused by {v} (Compound) Labetalol
Labetalol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iohexol
Paroxetine {u} (Compound) causes {v} (Side Effect) Dermatitis
Dermatitis {u} (Side Effect) is caused by {v} (Compound) Iodixanol
Iodixanol {u} (Compound) resembles {v} (Compound) Iohexol
Paroxetine {u} (Compound) causes {v} (Side Effect) Endocrine disorder
Endocrine disorder {u} (Side Effect) is caused by {v} (Compound) Escitalopram
Escitalopram {u} may lead to a major life threatening interaction when taken with {v} Iohexol
Paroxetine {u} (Compound) downregulates {v} (Gene) CCDC86
CCDC86 {u} (Gene) is regulated by {v} (Gene) ITGAE
ITGAE {u} (Gene) is downregulated by {v} (Compound) Iohexol
Paroxetine {u} (Compound) downregulates {v} (Gene) ITGAE
ITGAE {u} (Gene) is downregulated by {v} (Compound) Sulfasalazine
Sulfasalazine {u} may lead to a major life threatening interaction when taken with {v} Iohexol
Paroxetine {u} (Compound) causes {v} (Side Effect) Bone disorder
Bone disorder {u} (Side Effect) is caused by {v} (Compound) Dexmethylphenidate
Dexmethylphenidate {u} may lead to a major life threatening interaction when taken with {v} Iohexol
Paroxetine (Compound) downregulates PRR7 (Gene) and PRR7 (Gene) is downregulated by Iohexol (Compound)
Paroxetine (Compound) causes Hypersensitivity (Side Effect) and Hypersensitivity (Side Effect) is caused by Iohexol (Compound)
Paroxetine (Compound) downregulates PRR7 (Gene) and PRR7 (Gene) is downregulated by Trichlormethiazide (Compound) and Trichlormethiazide may cause a moderate interaction that could exacerbate diseases when taken with Iohexol
Paroxetine (Compound) downregulates ITGAE (Gene) and ITGAE (Gene) is downregulated by Iodixanol (Compound) and Iodixanol (Compound) resembles Iohexol (Compound)
Paroxetine (Compound) causes Hypersensitivity (Side Effect) and Hypersensitivity (Side Effect) is caused by Labetalol (Compound) and Labetalol may cause a moderate interaction that could exacerbate diseases when taken with Iohexol
Paroxetine (Compound) causes Dermatitis (Side Effect) and Dermatitis (Side Effect) is caused by Iodixanol (Compound) and Iodixanol (Compound) resembles Iohexol (Compound)
Paroxetine (Compound) causes Endocrine disorder (Side Effect) and Endocrine disorder (Side Effect) is caused by Escitalopram (Compound) and Escitalopram may lead to a major life threatening interaction when taken with Iohexol
Paroxetine (Compound) downregulates CCDC86 (Gene) and CCDC86 (Gene) is regulated by ITGAE (Gene) and ITGAE (Gene) is downregulated by Iohexol (Compound)
Paroxetine (Compound) downregulates ITGAE (Gene) and ITGAE (Gene) is downregulated by Sulfasalazine (Compound) and Sulfasalazine may lead to a major life threatening interaction when taken with Iohexol
Paroxetine (Compound) causes Bone disorder (Side Effect) and Bone disorder (Side Effect) is caused by Dexmethylphenidate (Compound) and Dexmethylphenidate may lead to a major life threatening interaction when taken with Iohexol