DDInter1767 DDInter1376
Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label]. Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate.
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26, 2020.[L12573,L12582] The US approval was followed by the approval in Canada on October 2, 2020. In November 2021, ozanimod was also approved by the European Commission for the treatment of adults with relapsing remitting multiple sclerosis.[L39377,L39382] MS is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Inflammatory bowel disease also a chronic inflammatory condition and can cause persistent abdominal pain, diarrhea, bloody stools, and vomiting. In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard in MS therapy. Studies involving patients with inflammatory bowel disease have also shown promising results.[A189318,A189342]
Terazosin {u} (Compound) resembles {v} (Compound) Prazosin
Terazosin {u} (Compound) treats {v} (Disease) hypertension
Terazosin {u} (Compound) binds {v} (Gene) ADRA1D
Terazosin {u} (Compound) upregulates {v} (Gene) CES1
Terazosin {u} (Compound) downregulates {v} (Gene) PUF60
Terazosin {u} (Compound) causes {v} (Side Effect) Atrial fibrillation
Terazosin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Finasteride
Terazosin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Morphine
Terazosin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dexamethasone
Terazosin (Compound) resembles Prazosin (Compound)
Terazosin (Compound) treats hypertension (Disease)
Terazosin (Compound) binds ADRA1D (Gene)
Terazosin (Compound) upregulates CES1 (Gene)
Terazosin (Compound) downregulates PUF60 (Gene)
Terazosin (Compound) causes Atrial fibrillation (Side Effect)
Terazosin may cause a minor interaction that can limit clinical effects when taken with Finasteride
Terazosin may cause a moderate interaction that could exacerbate diseases when taken with Morphine
Terazosin may cause a moderate interaction that could exacerbate diseases when taken with Dexamethasone