DDInter1650 DDInter178
Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. It is commonly known as quinalbarbitone in the United Kingdom.
Bendamustine is a nitrogen mustard drug indicated for use in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed during or within six months of treatment with rituximab or a rituximab-containing regimen. Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases resulting in cell death. It is active against both active and quiescent cells, although the exact mechanism of action is unknown.
Secobarbital {u} (Compound) resembles {v} (Compound) Amobarbital
Secobarbital {u} (Compound) resembles {v} (Compound) Thiopental
Secobarbital {u} (Compound) binds {v} (Gene) GRIK2
Secobarbital {u} (Compound) causes {v} (Side Effect) Hyperkinesia
Secobarbital {u} may cause a minor interaction that can limit clinical effects when taken with {v} Lidocaine
Secobarbital {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cimetidine
Secobarbital {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Irinotecan
Secobarbital {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Theophylline
Secobarbital {u} may lead to a major life threatening interaction when taken with {v} Morphine
Secobarbital {u} may lead to a major life threatening interaction when taken with {v} Hemin
Secobarbital (Compound) resembles Amobarbital (Compound)
Secobarbital (Compound) resembles Thiopental (Compound)
Secobarbital (Compound) binds GRIK2 (Gene)
Secobarbital (Compound) causes Hyperkinesia (Side Effect)
Secobarbital may cause a minor interaction that can limit clinical effects when taken with Lidocaine
Secobarbital may cause a minor interaction that can limit clinical effects when taken with Cimetidine
Secobarbital may cause a moderate interaction that could exacerbate diseases when taken with Irinotecan
Secobarbital may cause a moderate interaction that could exacerbate diseases when taken with Theophylline
Secobarbital may lead to a major life threatening interaction when taken with Morphine
Secobarbital may lead to a major life threatening interaction when taken with Hemin