DDInter1448 DDInter556
Phentolamine is a reversible, non-selective alpha-adrenergic blocker that induces vasodilation. While initially introduced to the market for the treatment of hypertension, this clinical use was halted due to cardiovascular and gastrointestinal adverse effects with the prolonged use of large oral doses of phentolamine.[A261781, A261786] It has several therapeutic uses, including the treatment of hypertensive episodes, prevention of norepinephrine-induced extravasation, diagnosis of pheochromocytoma, reversal of soft-tissue anesthesia, and treatment of pharmacologically-induced mydriasis.[L48420, L48415, L48390] Phentolamine is administered intravenously, intramuscularly, submucosally, and topically.
Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough. It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more effective antitussive agent to help reduce the spread of airborne infectious diseases such as tuburculosis. It was marketed in 1911.
Phentolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Morphine
Morphine {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Phentolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Hydromorphone
Hydromorphone {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Phentolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nalbuphine
Nalbuphine {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Phentolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Diamorphine
Diamorphine {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Phentolamine {u} (Compound) causes {v} (Side Effect) Mediastinal disorder
Mediastinal disorder {u} (Side Effect) is caused by {v} (Compound) Dihydrocodeine
Phentolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Morphine
Morphine {u} (Compound) resembles {v} (Compound) Galantamine
Galantamine {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Phentolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Hydromorphone
Hydromorphone {u} (Compound) resembles {v} (Compound) Oxymorphone
Oxymorphone {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Phentolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nalbuphine
Nalbuphine {u} (Compound) resembles {v} (Compound) Oxymorphone
Oxymorphone {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Phentolamine {u} (Compound) causes {v} (Side Effect) Mediastinal disorder
Mediastinal disorder {u} (Side Effect) is caused by {v} (Compound) Oxymorphone
Oxymorphone {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Phentolamine {u} (Compound) causes {v} (Side Effect) Headache
Headache {u} (Side Effect) is caused by {v} (Compound) Galantamine
Galantamine {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Phentolamine may cause a moderate interaction that could exacerbate diseases when taken with Morphine and Morphine (Compound) resembles Dihydrocodeine (Compound)
Phentolamine may cause a moderate interaction that could exacerbate diseases when taken with Hydromorphone and Hydromorphone (Compound) resembles Dihydrocodeine (Compound)
Phentolamine may cause a moderate interaction that could exacerbate diseases when taken with Nalbuphine and Nalbuphine (Compound) resembles Dihydrocodeine (Compound)
Phentolamine may cause a moderate interaction that could exacerbate diseases when taken with Diamorphine and Diamorphine (Compound) resembles Dihydrocodeine (Compound)
Phentolamine (Compound) causes Mediastinal disorder (Side Effect) and Mediastinal disorder (Side Effect) is caused by Dihydrocodeine (Compound)
Phentolamine may cause a moderate interaction that could exacerbate diseases when taken with Morphine and Morphine (Compound) resembles Galantamine (Compound) and Galantamine (Compound) resembles Dihydrocodeine (Compound)
Phentolamine may cause a moderate interaction that could exacerbate diseases when taken with Hydromorphone and Hydromorphone (Compound) resembles Oxymorphone (Compound) and Oxymorphone (Compound) resembles Dihydrocodeine (Compound)
Phentolamine may cause a moderate interaction that could exacerbate diseases when taken with Nalbuphine and Nalbuphine (Compound) resembles Oxymorphone (Compound) and Oxymorphone (Compound) resembles Dihydrocodeine (Compound)
Phentolamine (Compound) causes Mediastinal disorder (Side Effect) and Mediastinal disorder (Side Effect) is caused by Oxymorphone (Compound) and Oxymorphone (Compound) resembles Dihydrocodeine (Compound)
Phentolamine (Compound) causes Headache (Side Effect) and Headache (Side Effect) is caused by Galantamine (Compound) and Galantamine (Compound) resembles Dihydrocodeine (Compound)