DDInter548 DDInter1074
A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed) The FDA withdrew its approval for the use of all oral and parenteral drug products containing 25 milligrams or more of diethylstilbestrol per unit dose.
Liothyronine is a thyroidal hormone T3 which is normally produced by the thyroid gland in a ratio 4:1 when compared with T4: T3. Liothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine with bound iodine. The exogenous liothyronine product was developed by King Pharmaceuticals and FDA approved in 1956.
Diethylstilbestrol {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Liothyronine
Diethylstilbestrol {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Liotrix
Liotrix {u} (Compound) resembles {v} (Compound) Liothyronine
Diethylstilbestrol {u} (Compound) resembles {v} (Compound) Ritodrine
Ritodrine {u} (Compound) resembles {v} (Compound) Dobutamine
Dobutamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Liothyronine
Diethylstilbestrol {u} (Compound) resembles {v} (Compound) Dienestrol
Dienestrol {u} (Compound) upregulates {v} (Gene) ABCC5
ABCC5 {u} (Gene) is upregulated by {v} (Compound) Liothyronine
Diethylstilbestrol {u} (Compound) resembles {v} (Compound) Ritodrine
Ritodrine {u} (Compound) resembles {v} (Compound) Labetalol
Labetalol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Liothyronine
Diethylstilbestrol {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Simvastatin
Simvastatin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Liothyronine
Diethylstilbestrol {u} (Compound) resembles {v} (Compound) Ritodrine
Ritodrine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Theophylline
Theophylline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Liothyronine
Diethylstilbestrol {u} (Compound) binds {v} (Gene) TTR
TTR {u} (Gene) interacts with {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Liothyronine
Diethylstilbestrol {u} (Compound) binds {v} (Gene) CYP2C8
CYP2C8 {u} (Gene) is bound by {v} (Compound) Warfarin
Warfarin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Liothyronine
Diethylstilbestrol {u} (Compound) resembles {v} (Compound) Tamoxifen
Tamoxifen {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Liothyronine
Diethylstilbestrol (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Liothyronine (Compound)
Diethylstilbestrol (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Liotrix (Compound) and Liotrix (Compound) resembles Liothyronine (Compound)
Diethylstilbestrol (Compound) resembles Ritodrine (Compound) and Ritodrine (Compound) resembles Dobutamine (Compound) and Dobutamine may cause a moderate interaction that could exacerbate diseases when taken with Liothyronine
Diethylstilbestrol (Compound) resembles Dienestrol (Compound) and Dienestrol (Compound) upregulates ABCC5 (Gene) and ABCC5 (Gene) is upregulated by Liothyronine (Compound)
Diethylstilbestrol (Compound) resembles Ritodrine (Compound) and Ritodrine (Compound) resembles Labetalol (Compound) and Labetalol may cause a minor interaction that can limit clinical effects when taken with Liothyronine
Diethylstilbestrol (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Simvastatin (Compound) and Simvastatin may cause a minor interaction that can limit clinical effects when taken with Liothyronine
Diethylstilbestrol (Compound) resembles Ritodrine (Compound) and Ritodrine may cause a moderate interaction that could exacerbate diseases when taken with Theophylline and Theophylline may cause a moderate interaction that could exacerbate diseases when taken with Liothyronine
Diethylstilbestrol (Compound) binds TTR (Gene) and TTR (Gene) interacts with ALB (Gene) and ALB (Gene) is bound by Liothyronine (Compound)
Diethylstilbestrol (Compound) binds CYP2C8 (Gene) and CYP2C8 (Gene) is bound by Warfarin (Compound) and Warfarin may cause a moderate interaction that could exacerbate diseases when taken with Liothyronine
Diethylstilbestrol (Compound) resembles Tamoxifen (Compound) and Tamoxifen (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Liothyronine (Compound)