DDInter458 DDInter744
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus _Beauveria nivea_. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
A fluorinated cytosine analog that is used as an antifungal agent.
Cyclosporine {u} (Compound) downregulates {v} (Gene) DNMT1
DNMT1 {u} (Gene) is bound by {v} (Compound) Flucytosine
Cyclosporine {u} (Compound) upregulates {v} (Gene) COPB2
COPB2 {u} (Gene) is upregulated by {v} (Compound) Flucytosine
Cyclosporine {u} (Compound) downregulates {v} (Gene) GRWD1
GRWD1 {u} (Gene) is downregulated by {v} (Compound) Flucytosine
Cyclosporine {u} (Compound) upregulates {v} (Gene) TRIB1
TRIB1 {u} (Gene) is downregulated by {v} (Compound) Flucytosine
Cyclosporine {u} (Compound) causes {v} (Side Effect) Anorexia
Anorexia {u} (Side Effect) is caused by {v} (Compound) Flucytosine
Cyclosporine {u} (Compound) downregulates {v} (Gene) DNMT1
DNMT1 {u} (Gene) is regulated by {v} (Gene) POLD4
POLD4 {u} (Gene) is upregulated by {v} (Compound) Flucytosine
Cyclosporine {u} (Compound) upregulates {v} (Gene) COPB2
COPB2 {u} (Gene) is regulated by {v} (Gene) TIPARP
TIPARP {u} (Gene) is upregulated by {v} (Compound) Flucytosine
Cyclosporine {u} (Compound) downregulates {v} (Gene) GRWD1
GRWD1 {u} (Gene) regulates {v} (Gene) LIG1
LIG1 {u} (Gene) is downregulated by {v} (Compound) Flucytosine
Cyclosporine {u} (Compound) downregulates {v} (Gene) LIG1
LIG1 {u} (Gene) regulates {v} (Gene) DNMT1
DNMT1 {u} (Gene) is bound by {v} (Compound) Flucytosine
Cyclosporine {u} (Compound) downregulates {v} (Gene) MRPL12
MRPL12 {u} (Gene) is regulated by {v} (Gene) DNMT1
DNMT1 {u} (Gene) is bound by {v} (Compound) Flucytosine
Cyclosporine (Compound) downregulates DNMT1 (Gene) and DNMT1 (Gene) is bound by Flucytosine (Compound)
Cyclosporine (Compound) upregulates COPB2 (Gene) and COPB2 (Gene) is upregulated by Flucytosine (Compound)
Cyclosporine (Compound) downregulates GRWD1 (Gene) and GRWD1 (Gene) is downregulated by Flucytosine (Compound)
Cyclosporine (Compound) upregulates TRIB1 (Gene) and TRIB1 (Gene) is downregulated by Flucytosine (Compound)
Cyclosporine (Compound) causes Anorexia (Side Effect) and Anorexia (Side Effect) is caused by Flucytosine (Compound)
Cyclosporine (Compound) downregulates DNMT1 (Gene) and DNMT1 (Gene) is regulated by POLD4 (Gene) and POLD4 (Gene) is upregulated by Flucytosine (Compound)
Cyclosporine (Compound) upregulates COPB2 (Gene) and COPB2 (Gene) is regulated by TIPARP (Gene) and TIPARP (Gene) is upregulated by Flucytosine (Compound)
Cyclosporine (Compound) downregulates GRWD1 (Gene) and GRWD1 (Gene) regulates LIG1 (Gene) and LIG1 (Gene) is downregulated by Flucytosine (Compound)
Cyclosporine (Compound) downregulates LIG1 (Gene) and LIG1 (Gene) regulates DNMT1 (Gene) and DNMT1 (Gene) is bound by Flucytosine (Compound)
Cyclosporine (Compound) downregulates MRPL12 (Gene) and MRPL12 (Gene) is regulated by DNMT1 (Gene) and DNMT1 (Gene) is bound by Flucytosine (Compound)