DDInter154 DDInter1798
Azelastine is a phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position. It has a role as a H1-receptor antagonist, an anti-allergic agent, an anti-asthmatic drug, a bronchodilator agent, a platelet aggregation inhibitor and an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. It is a member of phthalazines, a tertiary amino compound and a member of monochlorobenzenes.
A thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics.
Azelastine {u} (Compound) resembles {v} (Compound) Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) Thiothixene
Azelastine {u} (Compound) binds {v} (Gene) HRH1
HRH1 {u} (Gene) is bound by {v} (Compound) Thiothixene
Azelastine {u} (Compound) upregulates {v} (Gene) SESN1
SESN1 {u} (Gene) is upregulated by {v} (Compound) Thiothixene
Azelastine {u} (Compound) downregulates {v} (Gene) PDHX
PDHX {u} (Gene) is downregulated by {v} (Compound) Thiothixene
Azelastine {u} (Compound) causes {v} (Side Effect) Cough
Cough {u} (Side Effect) is caused by {v} (Compound) Thiothixene
Azelastine {u} (Compound) resembles {v} (Compound) Loxapine
Loxapine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Doxepin
Doxepin {u} (Compound) resembles {v} (Compound) Thiothixene
Azelastine {u} (Compound) resembles {v} (Compound) Clozapine
Clozapine {u} may lead to a major life threatening interaction when taken with {v} Doxepin
Doxepin {u} (Compound) resembles {v} (Compound) Thiothixene
Azelastine {u} (Compound) binds {v} (Gene) HRH1
HRH1 {u} (Gene) is bound by {v} (Compound) Doxepin
Doxepin {u} (Compound) resembles {v} (Compound) Thiothixene
Azelastine {u} (Compound) upregulates {v} (Gene) SESN1
SESN1 {u} (Gene) is upregulated by {v} (Compound) Thioridazine
Thioridazine {u} (Compound) resembles {v} (Compound) Thiothixene
Azelastine {u} (Compound) downregulates {v} (Gene) PDHX
PDHX {u} (Gene) is downregulated by {v} (Compound) Thioridazine
Thioridazine {u} (Compound) resembles {v} (Compound) Thiothixene
Azelastine (Compound) resembles Loxapine (Compound) and Loxapine (Compound) resembles Thiothixene (Compound)
Azelastine (Compound) binds HRH1 (Gene) and HRH1 (Gene) is bound by Thiothixene (Compound)
Azelastine (Compound) upregulates SESN1 (Gene) and SESN1 (Gene) is upregulated by Thiothixene (Compound)
Azelastine (Compound) downregulates PDHX (Gene) and PDHX (Gene) is downregulated by Thiothixene (Compound)
Azelastine (Compound) causes Cough (Side Effect) and Cough (Side Effect) is caused by Thiothixene (Compound)
Azelastine (Compound) resembles Loxapine (Compound) and Loxapine may cause a moderate interaction that could exacerbate diseases when taken with Doxepin and Doxepin (Compound) resembles Thiothixene (Compound)
Azelastine (Compound) resembles Clozapine (Compound) and Clozapine may lead to a major life threatening interaction when taken with Doxepin and Doxepin (Compound) resembles Thiothixene (Compound)
Azelastine (Compound) binds HRH1 (Gene) and HRH1 (Gene) is bound by Doxepin (Compound) and Doxepin (Compound) resembles Thiothixene (Compound)
Azelastine (Compound) upregulates SESN1 (Gene) and SESN1 (Gene) is upregulated by Thioridazine (Compound) and Thioridazine (Compound) resembles Thiothixene (Compound)
Azelastine (Compound) downregulates PDHX (Gene) and PDHX (Gene) is downregulated by Thioridazine (Compound) and Thioridazine (Compound) resembles Thiothixene (Compound)