DDInter1912 DDInter178
Valganciclovir hydrochloride (Valcyte, manufactured by Roche) is an antiviral medication used to treat cytomegalovirus infections. As the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases.
Bendamustine is a nitrogen mustard drug indicated for use in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed during or within six months of treatment with rituximab or a rituximab-containing regimen. Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases resulting in cell death. It is active against both active and quiescent cells, although the exact mechanism of action is unknown.
Valganciclovir {u} (Compound) resembles {v} (Compound) Penciclovir
Valganciclovir {u} (Compound) resembles {v} (Compound) Acyclovir
Valganciclovir {u} (Compound) binds {v} (Gene) SLC15A1
Valganciclovir {u} (Compound) is included by {v} (Pharmacologic Class) Nucleoside Analog
Valganciclovir {u} (Compound) causes {v} (Side Effect) Anorexia
Valganciclovir {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Bexarotene
Valganciclovir {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acalabrutinib
Valganciclovir {u} may lead to a major life threatening interaction when taken with {v} Certolizumab pegol
Valganciclovir {u} may lead to a major life threatening interaction when taken with {v} Infliximab
Valganciclovir (Compound) resembles Penciclovir (Compound)
Valganciclovir (Compound) resembles Acyclovir (Compound)
Valganciclovir (Compound) binds SLC15A1 (Gene)
Valganciclovir (Compound) is included by Nucleoside Analog (Pharmacologic Class)
Valganciclovir (Compound) causes Anorexia (Side Effect)
Valganciclovir may cause a moderate interaction that could exacerbate diseases when taken with Bexarotene
Valganciclovir may cause a moderate interaction that could exacerbate diseases when taken with Acalabrutinib
Valganciclovir may lead to a major life threatening interaction when taken with Certolizumab pegol
Valganciclovir may lead to a major life threatening interaction when taken with Infliximab