DDInter130 DDInter195
Atenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. Sir James Black, a Scottish pharmacologist, pioneered the use of beta-blockers for the management of angina pectoris in 1958 for which he received the Nobel Prize. Beta-blockers quickly became popular in clinical use and where subsequently investigated for use in myocardial infarction, arrhythmias, and hypertension during the 1960s. Later they continued to be investigated for use in heart failure throughout the 1970-1980s. Atenolol itself was developed early on in this history by Alvogen Malta under the trade name Tenormin and received FDA approval in September, 1981.[label] Despite being one of the most widely prescribed beta blockers, evidence suggests atenolol may not significantly reduce mortality, and only modestly reduce the risk of cardiovascular disease in patients with hypertension.[A235850,A235855] A Cochrane review
Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.
Atenolol {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Betamethasone
Atenolol {u} (Compound) causes {v} (Side Effect) Feeling abnormal
Feeling abnormal {u} (Side Effect) is caused by {v} (Compound) Betamethasone
Atenolol {u} (Compound) resembles {v} (Compound) Bisoprolol
Bisoprolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Betamethasone
Atenolol {u} (Compound) resembles {v} (Compound) Acebutolol
Acebutolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Betamethasone
Atenolol {u} (Compound) resembles {v} (Compound) Metoprolol
Metoprolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Betamethasone
Atenolol {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Fluticasone furoate
Fluticasone furoate {u} (Compound) resembles {v} (Compound) Betamethasone
Atenolol {u} (Compound) causes {v} (Side Effect) Feeling abnormal
Feeling abnormal {u} (Side Effect) is caused by {v} (Compound) Budesonide
Budesonide {u} (Compound) resembles {v} (Compound) Betamethasone
Atenolol {u} (Compound) causes {v} (Side Effect) Cardiomegaly
Cardiomegaly {u} (Side Effect) is caused by {v} (Compound) Fludrocortisone
Fludrocortisone {u} (Compound) resembles {v} (Compound) Betamethasone
Atenolol {u} (Compound) resembles {v} (Compound) Bisoprolol
Bisoprolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Budesonide
Budesonide {u} (Compound) resembles {v} (Compound) Betamethasone
Atenolol {u} (Compound) resembles {v} (Compound) Acebutolol
Acebutolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Budesonide
Budesonide {u} (Compound) resembles {v} (Compound) Betamethasone
Atenolol (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Betamethasone (Compound)
Atenolol (Compound) causes Feeling abnormal (Side Effect) and Feeling abnormal (Side Effect) is caused by Betamethasone (Compound)
Atenolol (Compound) resembles Bisoprolol (Compound) and Bisoprolol may cause a moderate interaction that could exacerbate diseases when taken with Betamethasone
Atenolol (Compound) resembles Acebutolol (Compound) and Acebutolol may cause a moderate interaction that could exacerbate diseases when taken with Betamethasone
Atenolol (Compound) resembles Metoprolol (Compound) and Metoprolol may cause a moderate interaction that could exacerbate diseases when taken with Betamethasone
Atenolol (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Fluticasone furoate (Compound) and Fluticasone furoate (Compound) resembles Betamethasone (Compound)
Atenolol (Compound) causes Feeling abnormal (Side Effect) and Feeling abnormal (Side Effect) is caused by Budesonide (Compound) and Budesonide (Compound) resembles Betamethasone (Compound)
Atenolol (Compound) causes Cardiomegaly (Side Effect) and Cardiomegaly (Side Effect) is caused by Fludrocortisone (Compound) and Fludrocortisone (Compound) resembles Betamethasone (Compound)
Atenolol (Compound) resembles Bisoprolol (Compound) and Bisoprolol may cause a moderate interaction that could exacerbate diseases when taken with Budesonide and Budesonide (Compound) resembles Betamethasone (Compound)
Atenolol (Compound) resembles Acebutolol (Compound) and Acebutolol may cause a moderate interaction that could exacerbate diseases when taken with Budesonide and Budesonide (Compound) resembles Betamethasone (Compound)