DDInter948 DDInter1821
Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury . It may also be caused by musculoskeletal injury . Regardless of the cause, muscle spasticity can be an extremely painful and debilitating condition. Initially approved by the FDA in 1996, tizanidine is an Alpha-2 adrenergic receptor agonist reducing spasticity by the presynaptic inhibition of excitatory neurotransmitters that cause firing of neurons promoting muscle spasm [FDA label].
Tizanidine {u} (Compound) resembles {v} (Compound) Brimonidine
Tizanidine {u} (Compound) binds {v} (Gene) CYP1A2
Tizanidine {u} (Compound) upregulates {v} (Gene) CDK6
Tizanidine {u} (Compound) palliates {v} (Disease) multiple sclerosis
Tizanidine {u} (Compound) is included by {v} (Pharmacologic Class) Adrenergic alpha2-Agonists
Tizanidine {u} (Compound) downregulates {v} (Gene) USP22
Tizanidine {u} (Compound) causes {v} (Side Effect) Autonomic nervous system imbalance
Tizanidine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metronidazole
Tizanidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Promethazine
Tizanidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Interferon beta-1a
Tizanidine (Compound) resembles Brimonidine (Compound)
Tizanidine (Compound) binds CYP1A2 (Gene)
Tizanidine (Compound) upregulates CDK6 (Gene)
Tizanidine (Compound) palliates multiple sclerosis (Disease)
Tizanidine (Compound) is included by Adrenergic alpha2-Agonists (Pharmacologic Class)
Tizanidine (Compound) downregulates USP22 (Gene)
Tizanidine (Compound) causes Autonomic nervous system imbalance (Side Effect)
Tizanidine may cause a minor interaction that can limit clinical effects when taken with Metronidazole
Tizanidine may cause a moderate interaction that could exacerbate diseases when taken with Promethazine
Tizanidine may cause a moderate interaction that could exacerbate diseases when taken with Interferon beta-1a