DDInter581 DDInter396
Dolasetron is an antinauseant and antiemetic agent indicated for the prevention of nausea and vomiting associated with moderately-emetogenic cancer chemotherapy and for the prevention of postoperative nausea and vomiting. Dolasetron is a highly specific and selective serotonin 5-HT3 receptor antagonist. This drug is not shown to have activity at other known serotonin receptors, and has low affinity for dopamine receptors.
Clevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.
Dolasetron {u} may lead to a major life threatening interaction when taken with {v} Nicardipine
Nicardipine {u} (Compound) resembles {v} (Compound) Clevidipine
Dolasetron {u} may lead to a major life threatening interaction when taken with {v} Nifedipine
Nifedipine {u} (Compound) resembles {v} (Compound) Clevidipine
Dolasetron {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Clevidipine
Dolasetron {u} (Compound) causes {v} (Side Effect) Acute coronary syndrome
Acute coronary syndrome {u} (Side Effect) is caused by {v} (Compound) Clevidipine
Dolasetron {u} may lead to a major life threatening interaction when taken with {v} Nicardipine
Nicardipine {u} (Compound) resembles {v} (Compound) Nitrendipine
Nitrendipine {u} (Compound) resembles {v} (Compound) Clevidipine
Dolasetron {u} may lead to a major life threatening interaction when taken with {v} Nifedipine
Nifedipine {u} (Compound) resembles {v} (Compound) Nitrendipine
Nitrendipine {u} (Compound) resembles {v} (Compound) Clevidipine
Dolasetron {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Nicardipine
Nicardipine {u} (Compound) resembles {v} (Compound) Clevidipine
Dolasetron {u} (Compound) causes {v} (Side Effect) Acute coronary syndrome
Acute coronary syndrome {u} (Side Effect) is caused by {v} (Compound) Nicardipine
Nicardipine {u} (Compound) resembles {v} (Compound) Clevidipine
Dolasetron {u} (Compound) upregulates {v} (Gene) MCOLN1
MCOLN1 {u} (Gene) is upregulated by {v} (Compound) Nitrendipine
Nitrendipine {u} (Compound) resembles {v} (Compound) Clevidipine
Dolasetron {u} may lead to a major life threatening interaction when taken with {v} Nicardipine
Nicardipine {u} (Compound) resembles {v} (Compound) Nifedipine
Nifedipine {u} (Compound) resembles {v} (Compound) Clevidipine
Dolasetron may lead to a major life threatening interaction when taken with Nicardipine and Nicardipine (Compound) resembles Clevidipine (Compound)
Dolasetron may lead to a major life threatening interaction when taken with Nifedipine and Nifedipine (Compound) resembles Clevidipine (Compound)
Dolasetron (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Clevidipine (Compound)
Dolasetron (Compound) causes Acute coronary syndrome (Side Effect) and Acute coronary syndrome (Side Effect) is caused by Clevidipine (Compound)
Dolasetron may lead to a major life threatening interaction when taken with Nicardipine and Nicardipine (Compound) resembles Nitrendipine (Compound) and Nitrendipine (Compound) resembles Clevidipine (Compound)
Dolasetron may lead to a major life threatening interaction when taken with Nifedipine and Nifedipine (Compound) resembles Nitrendipine (Compound) and Nitrendipine (Compound) resembles Clevidipine (Compound)
Dolasetron (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Nicardipine (Compound) and Nicardipine (Compound) resembles Clevidipine (Compound)
Dolasetron (Compound) causes Acute coronary syndrome (Side Effect) and Acute coronary syndrome (Side Effect) is caused by Nicardipine (Compound) and Nicardipine (Compound) resembles Clevidipine (Compound)
Dolasetron (Compound) upregulates MCOLN1 (Gene) and MCOLN1 (Gene) is upregulated by Nitrendipine (Compound) and Nitrendipine (Compound) resembles Clevidipine (Compound)
Dolasetron may lead to a major life threatening interaction when taken with Nicardipine and Nicardipine (Compound) resembles Nifedipine (Compound) and Nifedipine (Compound) resembles Clevidipine (Compound)