DDInter1522 DDInter833
The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
Glycerol phenylbutyrate is a nitrogen-binding agent. Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol backbone. FDA approved on February 1, 2013.
Probenecid {u} (Compound) causes {v} (Side Effect) Decreased appetite
Decreased appetite {u} (Side Effect) is caused by {v} (Compound) Glycerol phenylbutyrate
Probenecid {u} may cause a minor interaction that can limit clinical effects when taken with {v} Diclofenac
Diclofenac {u} (Compound) causes {v} (Side Effect) Asthenia
Asthenia {u} (Side Effect) is caused by {v} (Compound) Glycerol phenylbutyrate
Probenecid {u} may lead to a major life threatening interaction when taken with {v} Methotrexate
Methotrexate {u} (Compound) causes {v} (Side Effect) Asthenia
Asthenia {u} (Side Effect) is caused by {v} (Compound) Glycerol phenylbutyrate
Probenecid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mycophenolic acid
Mycophenolic acid {u} (Compound) causes {v} (Side Effect) Asthenia
Asthenia {u} (Side Effect) is caused by {v} (Compound) Glycerol phenylbutyrate
Probenecid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Glipizide
Glipizide {u} (Compound) causes {v} (Side Effect) Asthenia
Asthenia {u} (Side Effect) is caused by {v} (Compound) Glycerol phenylbutyrate
Probenecid {u} (Compound) resembles {v} (Compound) Procainamide
Procainamide {u} (Compound) causes {v} (Side Effect) Asthenia
Asthenia {u} (Side Effect) is caused by {v} (Compound) Glycerol phenylbutyrate
Probenecid {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ibuprofen
Ibuprofen {u} (Compound) causes {v} (Side Effect) Asthenia
Asthenia {u} (Side Effect) is caused by {v} (Compound) Glycerol phenylbutyrate
Probenecid {u} (Compound) resembles {v} (Compound) Chlorpropamide
Chlorpropamide {u} (Compound) causes {v} (Side Effect) Decreased appetite
Decreased appetite {u} (Side Effect) is caused by {v} (Compound) Glycerol phenylbutyrate
Probenecid (Compound) causes Decreased appetite (Side Effect) and Decreased appetite (Side Effect) is caused by Glycerol phenylbutyrate (Compound)
Probenecid may cause a minor interaction that can limit clinical effects when taken with Diclofenac and Diclofenac (Compound) causes Asthenia (Side Effect) and Asthenia (Side Effect) is caused by Glycerol phenylbutyrate (Compound)
Probenecid may lead to a major life threatening interaction when taken with Methotrexate and Methotrexate (Compound) causes Asthenia (Side Effect) and Asthenia (Side Effect) is caused by Glycerol phenylbutyrate (Compound)
Probenecid may cause a moderate interaction that could exacerbate diseases when taken with Mycophenolic acid and Mycophenolic acid (Compound) causes Asthenia (Side Effect) and Asthenia (Side Effect) is caused by Glycerol phenylbutyrate (Compound)
Probenecid may cause a moderate interaction that could exacerbate diseases when taken with Glipizide and Glipizide (Compound) causes Asthenia (Side Effect) and Asthenia (Side Effect) is caused by Glycerol phenylbutyrate (Compound)
Probenecid (Compound) resembles Procainamide (Compound) and Procainamide (Compound) causes Asthenia (Side Effect) and Asthenia (Side Effect) is caused by Glycerol phenylbutyrate (Compound)
Probenecid may cause a minor interaction that can limit clinical effects when taken with Ibuprofen and Ibuprofen (Compound) causes Asthenia (Side Effect) and Asthenia (Side Effect) is caused by Glycerol phenylbutyrate (Compound)
Probenecid (Compound) resembles Chlorpropamide (Compound) and Chlorpropamide (Compound) causes Decreased appetite (Side Effect) and Decreased appetite (Side Effect) is caused by Glycerol phenylbutyrate (Compound)