DDInter721 DDInter899
An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase. It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in November 2013 for the treatment of mantle cell lymphoma (MCL) under accelerated approval; however, in April 2023, the drug manufacturer withdrew the accelerated approvals for ibrutinib in the US. Ibrutinib was approved by the EMA in October 2014 and by Health Canada in November 2014. It is currently approved for the treatment of various conditions, such as chronic lymphocytic leukemia (CLL), Waldenström's Macroglobulinemia, and chronic graft versus host disease (cGVHD) in August 2017. Notably, ibrutinib became the first FDA-approved cGVHD treatment for children in August 2017.
Fenoprofen {u} (Compound) resembles {v} (Compound) Fenbufen
Fenoprofen {u} (Compound) binds {v} (Gene) ALB
Fenoprofen {u} (Compound) palliates {v} (Disease) osteoarthritis
Fenoprofen {u} (Compound) is included by {v} (Pharmacologic Class) Nonsteroidal Anti-inflammatory Compounds
Fenoprofen {u} (Compound) causes {v} (Side Effect) Dyspepsia
Fenoprofen (Compound) resembles Fenbufen (Compound)
Fenoprofen (Compound) binds ALB (Gene)
Fenoprofen (Compound) palliates osteoarthritis (Disease)
Fenoprofen (Compound) is included by Nonsteroidal Anti-inflammatory Compounds (Pharmacologic Class)
Fenoprofen (Compound) causes Dyspepsia (Side Effect)