DDInter815 DDInter957
Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea_ in 1963. It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability.[A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment of severe gram-negative infections including those caused by _Pseudomonas aeruginosa_.[A233325,A234359,A234364] There is the added benefit of synergy when gentamicin is co-administered with other antibacterials such as beta-lactams. This synergistic activity is not only important for the treatment of complex infections, but can also contribute to dose optimization and reduced adverse effects.[A234359,A234364] Although gentamicin is well-established and may be used in a variety of clinical applications,
Iodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.
Gentamicin {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Gentamicin {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Diatrizoate
Diatrizoate {u} (Compound) resembles {v} (Compound) Iodipamide
Gentamicin {u} (Compound) binds {v} (Gene) LRP2
LRP2 {u} (Gene) interacts with {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Gentamicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Piroxicam
Piroxicam {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Gentamicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ibuprofen
Ibuprofen {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Gentamicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ibuprofen
Ibuprofen {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Gentamicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indomethacin
Indomethacin {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Gentamicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Estradiol
Estradiol {u} (Compound) downregulates {v} (Gene) GRB7
GRB7 {u} (Gene) is downregulated by {v} (Compound) Iodipamide
Gentamicin {u} may lead to a major life threatening interaction when taken with {v} Etacrynic acid
Etacrynic acid {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Gentamicin {u} may lead to a major life threatening interaction when taken with {v} Etacrynic acid
Etacrynic acid {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Gentamicin (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Iodipamide (Compound)
Gentamicin (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Diatrizoate (Compound) and Diatrizoate (Compound) resembles Iodipamide (Compound)
Gentamicin (Compound) binds LRP2 (Gene) and LRP2 (Gene) interacts with ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Gentamicin may cause a moderate interaction that could exacerbate diseases when taken with Piroxicam and Piroxicam (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Gentamicin may cause a moderate interaction that could exacerbate diseases when taken with Ibuprofen and Ibuprofen (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Gentamicin may cause a moderate interaction that could exacerbate diseases when taken with Ibuprofen and Ibuprofen (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Iodipamide (Compound)
Gentamicin may cause a moderate interaction that could exacerbate diseases when taken with Indomethacin and Indomethacin (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Iodipamide (Compound)
Gentamicin may cause a moderate interaction that could exacerbate diseases when taken with Estradiol and Estradiol (Compound) downregulates GRB7 (Gene) and GRB7 (Gene) is downregulated by Iodipamide (Compound)
Gentamicin may lead to a major life threatening interaction when taken with Etacrynic acid and Etacrynic acid (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Gentamicin may lead to a major life threatening interaction when taken with Etacrynic acid and Etacrynic acid (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Iodipamide (Compound)