DDInter1253 DDInter536
Nabilone (marketed as Cesamet) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). Although structurally distinct from THC, nabilone mimics THC's structure and pharmacological activity through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, however it is considered to be twice as active as Δ⁹-THC. Nabilone is approved by the FDA for the treatment of nausea and vomiting associated with cancer chemotherapy in patients who have failed to respond adequately to conventional antiemetic treatments [FDA Label]. Tetrahydrocannabinol (THC) and cannabidiol (CBD) are the two most abundant cannabinoids found naturally in the resin of the marijuana plant, both of which are pharmacologically active due to their interaction with cannabinoid receptors that are
Dichloralphenazone is a sedative composed of chloral hydrate and phenazone. It is typically found in combination products Nodolor and Midrin containing [isometheptene] and [acetaminophen] used for the relief of tension and vascular headaches. It is a US Schedule IV drug and its clinical use is limited.
Nabilone {u} (Compound) resembles {v} (Compound) Dronabinol
Nabilone {u} (Compound) binds {v} (Gene) CNR2
Nabilone {u} (Compound) is included by {v} (Pharmacologic Class) Cannabinoids
Nabilone {u} (Compound) causes {v} (Side Effect) Lightheadedness
Nabilone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pindolol
Nabilone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Thiethylperazine
Nabilone {u} may lead to a major life threatening interaction when taken with {v} Levacetylmethadol
Nabilone (Compound) resembles Dronabinol (Compound)
Nabilone (Compound) binds CNR2 (Gene)
Nabilone (Compound) is included by Cannabinoids (Pharmacologic Class)
Nabilone (Compound) causes Lightheadedness (Side Effect)
Nabilone may cause a moderate interaction that could exacerbate diseases when taken with Pindolol
Nabilone may cause a moderate interaction that could exacerbate diseases when taken with Thiethylperazine
Nabilone may lead to a major life threatening interaction when taken with Levacetylmethadol