DDInter1311 DDInter1635
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.[L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 adrenergic receptor agonist, [salbutamol]. Salmeterol was first described in the literature in 1988. Salmeterol's structure is similar to salbutamol's with an aralkyloxy-alkyl substitution on the amine. Salmeterol was granted FDA approval on 4 February 1994.
Norepinephrine {u} (Compound) resembles {v} (Compound) Salbutamol
Salbutamol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Salmeterol
Norepinephrine {u} (Compound) resembles {v} (Compound) Arbutamine
Arbutamine {u} (Compound) resembles {v} (Compound) Salmeterol
Norepinephrine {u} (Compound) binds {v} (Gene) ADRB2
ADRB2 {u} (Gene) is bound by {v} (Compound) Salmeterol
Norepinephrine {u} (Compound) causes {v} (Side Effect) Hypertension
Hypertension {u} (Side Effect) is caused by {v} (Compound) Salmeterol
Norepinephrine {u} (Compound) resembles {v} (Compound) Epinephrine
Epinephrine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Salmeterol
Norepinephrine {u} (Compound) resembles {v} (Compound) Phenylephrine
Phenylephrine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Salmeterol
Norepinephrine {u} (Compound) resembles {v} (Compound) Dopamine
Dopamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Salmeterol
Norepinephrine {u} (Compound) resembles {v} (Compound) Salbutamol
Salbutamol {u} may lead to a major life threatening interaction when taken with {v} Labetalol
Labetalol {u} may lead to a major life threatening interaction when taken with {v} Salmeterol
Norepinephrine {u} (Compound) resembles {v} (Compound) Arbutamine
Arbutamine {u} (Compound) resembles {v} (Compound) Labetalol
Labetalol {u} may lead to a major life threatening interaction when taken with {v} Salmeterol
Norepinephrine {u} (Compound) binds {v} (Gene) ADRB2
ADRB2 {u} (Gene) is bound by {v} (Compound) Labetalol
Labetalol {u} may lead to a major life threatening interaction when taken with {v} Salmeterol
Norepinephrine (Compound) resembles Salbutamol (Compound) and Salbutamol may cause a moderate interaction that could exacerbate diseases when taken with Salmeterol
Norepinephrine (Compound) resembles Arbutamine (Compound) and Arbutamine (Compound) resembles Salmeterol (Compound)
Norepinephrine (Compound) binds ADRB2 (Gene) and ADRB2 (Gene) is bound by Salmeterol (Compound)
Norepinephrine (Compound) causes Hypertension (Side Effect) and Hypertension (Side Effect) is caused by Salmeterol (Compound)
Norepinephrine (Compound) resembles Epinephrine (Compound) and Epinephrine may cause a moderate interaction that could exacerbate diseases when taken with Salmeterol
Norepinephrine (Compound) resembles Phenylephrine (Compound) and Phenylephrine may cause a moderate interaction that could exacerbate diseases when taken with Salmeterol
Norepinephrine (Compound) resembles Dopamine (Compound) and Dopamine may cause a moderate interaction that could exacerbate diseases when taken with Salmeterol
Norepinephrine (Compound) resembles Salbutamol (Compound) and Salbutamol may lead to a major life threatening interaction when taken with Labetalol and Labetalol may lead to a major life threatening interaction when taken with Salmeterol
Norepinephrine (Compound) resembles Arbutamine (Compound) and Arbutamine (Compound) resembles Labetalol (Compound) and Labetalol may lead to a major life threatening interaction when taken with Salmeterol
Norepinephrine (Compound) binds ADRB2 (Gene) and ADRB2 (Gene) is bound by Labetalol (Compound) and Labetalol may lead to a major life threatening interaction when taken with Salmeterol