DDInter885 DDInter131
Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. Hydrocortisone was granted FDA approval on 5 August 1952.
Atezolizumab is a humanized monoclonal antibody used to prevent the interaction of PD-L1 and PD-1, removing inhibition of immune responses seen in some cancers.[A18493,L7489] This medication is reserved for patients whose tumors express PD-L1, cannot receive platinum-based chemotherapy, or whose tumors do not respond to platinum-based chemotherapy. Atezolizumab was granted FDA approval on 18 October 2016. In November 2022, the manufacturer (Genentech) voluntarily withdrew the use of atezolizumab for the treatment of urothelial carcinoma, previously approved under the FDA's Accelerated Approval Program. The rest of atezolizumab indications remain unaffected.
Hydrocortisone {u} (Compound) resembles {v} (Compound) Loteprednol
Hydrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eplerenone
Hydrocortisone {u} (Compound) resembles {v} (Compound) Fludrocortisone
Hydrocortisone {u} (Compound) treats {v} (Disease) gout
Hydrocortisone {u} (Compound) binds {v} (Gene) CYP11B1
Hydrocortisone {u} (Compound) upregulates {v} (Gene) PRKCD
Hydrocortisone {u} (Compound) palliates {v} (Disease) prostate cancer
Hydrocortisone {u} (Compound) is included by {v} (Pharmacologic Class) Corticosteroid Hormone Receptor Agonists
Hydrocortisone {u} (Compound) downregulates {v} (Gene) AMIGO2
Hydrocortisone {u} (Compound) causes {v} (Side Effect) Papilloedema
Hydrocortisone (Compound) resembles Loteprednol (Compound)
Hydrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Eplerenone
Hydrocortisone (Compound) resembles Fludrocortisone (Compound)
Hydrocortisone (Compound) treats gout (Disease)
Hydrocortisone (Compound) binds CYP11B1 (Gene)
Hydrocortisone (Compound) upregulates PRKCD (Gene)
Hydrocortisone (Compound) palliates prostate cancer (Disease)
Hydrocortisone (Compound) is included by Corticosteroid Hormone Receptor Agonists (Pharmacologic Class)
Hydrocortisone (Compound) downregulates AMIGO2 (Gene)
Hydrocortisone (Compound) causes Papilloedema (Side Effect)