DDInter258 DDInter535
A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.[A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity. Diazoxide is commonly used in the treatment of hyperinsulinaemic hypoglycemia due to its ability to inhibit insulin release. Diazoxide also exhibits hypotensive activity and reduces arteriolar smooth muscle and vascular resistance. When administered intravenously, diazoxide can be used to treat hypertensive emergencies; however, this specific form of diazoxide is no longer available in the US. Diazoxide is usually well tolerated, and some of its more common side effects include fluid retention and electrolyte disturbances. In September 2015, the FDA issued a safety alert regarding post-marketing reports of pulmonary hypertension occurring in infants and neonates.[A255647,L44612]
Butorphanol {u} (Compound) causes {v} (Side Effect) Anorexia
Anorexia {u} (Side Effect) is caused by {v} (Compound) Diazoxide
Butorphanol {u} (Compound) causes {v} (Side Effect) Anorexia
Anorexia {u} (Side Effect) is caused by {v} (Compound) Chlorothiazide
Chlorothiazide {u} (Compound) resembles {v} (Compound) Diazoxide
Butorphanol {u} (Compound) resembles {v} (Compound) Naltrexone
Naltrexone {u} (Compound) downregulates {v} (Gene) MTHFD2
MTHFD2 {u} (Gene) is downregulated by {v} (Compound) Diazoxide
Butorphanol {u} (Compound) resembles {v} (Compound) Pentazocine
Pentazocine {u} (Compound) causes {v} (Side Effect) Eosinophilia
Eosinophilia {u} (Side Effect) is caused by {v} (Compound) Diazoxide
Butorphanol {u} (Compound) resembles {v} (Compound) Buprenorphine
Buprenorphine {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Diazoxide
Butorphanol {u} (Compound) resembles {v} (Compound) Levorphanol
Levorphanol {u} (Compound) upregulates {v} (Gene) DDX42
DDX42 {u} (Gene) is upregulated by {v} (Compound) Diazoxide
Butorphanol {u} (Compound) resembles {v} (Compound) Levorphanol
Levorphanol {u} (Compound) downregulates {v} (Gene) RBM34
RBM34 {u} (Gene) is downregulated by {v} (Compound) Diazoxide
Butorphanol {u} (Compound) resembles {v} (Compound) Dextromethorphan
Dextromethorphan {u} (Compound) upregulates {v} (Gene) MTHFD2
MTHFD2 {u} (Gene) is downregulated by {v} (Compound) Diazoxide
Butorphanol (Compound) causes Anorexia (Side Effect) and Anorexia (Side Effect) is caused by Diazoxide (Compound)
Butorphanol (Compound) causes Anorexia (Side Effect) and Anorexia (Side Effect) is caused by Chlorothiazide (Compound) and Chlorothiazide (Compound) resembles Diazoxide (Compound)
Butorphanol (Compound) resembles Naltrexone (Compound) and Naltrexone (Compound) downregulates MTHFD2 (Gene) and MTHFD2 (Gene) is downregulated by Diazoxide (Compound)
Butorphanol (Compound) resembles Pentazocine (Compound) and Pentazocine (Compound) causes Eosinophilia (Side Effect) and Eosinophilia (Side Effect) is caused by Diazoxide (Compound)
Butorphanol (Compound) resembles Buprenorphine (Compound) and Buprenorphine (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Diazoxide (Compound)
Butorphanol (Compound) resembles Levorphanol (Compound) and Levorphanol (Compound) upregulates DDX42 (Gene) and DDX42 (Gene) is upregulated by Diazoxide (Compound)
Butorphanol (Compound) resembles Levorphanol (Compound) and Levorphanol (Compound) downregulates RBM34 (Gene) and RBM34 (Gene) is downregulated by Diazoxide (Compound)
Butorphanol (Compound) resembles Dextromethorphan (Compound) and Dextromethorphan (Compound) upregulates MTHFD2 (Gene) and MTHFD2 (Gene) is downregulated by Diazoxide (Compound)