DDInter1867 DDInter1768
A phenothiazine used as an antipsychotic agent and as an antiemetic.
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell wall synthesis pathway.[A1279,A1281,L9068] Terbinafine hydrochloride was granted FDA approval on 30 December 1992.
Triflupromazine {u} (Compound) upregulates {v} (Gene) SQLE
SQLE {u} (Gene) is bound by {v} (Compound) Terbinafine
Triflupromazine {u} (Compound) upregulates {v} (Gene) NPC1
NPC1 {u} (Gene) is upregulated by {v} (Compound) Terbinafine
Triflupromazine {u} (Compound) downregulates {v} (Gene) PIN1
PIN1 {u} (Gene) is downregulated by {v} (Compound) Terbinafine
Triflupromazine {u} (Compound) upregulates {v} (Gene) GRN
GRN {u} (Gene) is downregulated by {v} (Compound) Terbinafine
Triflupromazine {u} (Compound) resembles {v} (Compound) Alimemazine
Alimemazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Terbinafine
Triflupromazine {u} (Compound) resembles {v} (Compound) Trifluoperazine
Trifluoperazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Terbinafine
Triflupromazine {u} (Compound) resembles {v} (Compound) Thioridazine
Thioridazine {u} may lead to a major life threatening interaction when taken with {v} Terbinafine
Triflupromazine {u} (Compound) upregulates {v} (Gene) SQLE
SQLE {u} (Gene) is bound by {v} (Compound) Naftifine
Naftifine {u} (Compound) resembles {v} (Compound) Terbinafine
Triflupromazine {u} (Compound) upregulates {v} (Gene) NPC1
NPC1 {u} (Gene) regulates {v} (Gene) FOXO4
FOXO4 {u} (Gene) is upregulated by {v} (Compound) Terbinafine
Triflupromazine {u} (Compound) downregulates {v} (Gene) PIN1
PIN1 {u} (Gene) regulates {v} (Gene) RHOA
RHOA {u} (Gene) is upregulated by {v} (Compound) Terbinafine
Triflupromazine (Compound) upregulates SQLE (Gene) and SQLE (Gene) is bound by Terbinafine (Compound)
Triflupromazine (Compound) upregulates NPC1 (Gene) and NPC1 (Gene) is upregulated by Terbinafine (Compound)
Triflupromazine (Compound) downregulates PIN1 (Gene) and PIN1 (Gene) is downregulated by Terbinafine (Compound)
Triflupromazine (Compound) upregulates GRN (Gene) and GRN (Gene) is downregulated by Terbinafine (Compound)
Triflupromazine (Compound) resembles Alimemazine (Compound) and Alimemazine may cause a moderate interaction that could exacerbate diseases when taken with Terbinafine
Triflupromazine (Compound) resembles Trifluoperazine (Compound) and Trifluoperazine may cause a moderate interaction that could exacerbate diseases when taken with Terbinafine
Triflupromazine (Compound) resembles Thioridazine (Compound) and Thioridazine may lead to a major life threatening interaction when taken with Terbinafine
Triflupromazine (Compound) upregulates SQLE (Gene) and SQLE (Gene) is bound by Naftifine (Compound) and Naftifine (Compound) resembles Terbinafine (Compound)
Triflupromazine (Compound) upregulates NPC1 (Gene) and NPC1 (Gene) regulates FOXO4 (Gene) and FOXO4 (Gene) is upregulated by Terbinafine (Compound)
Triflupromazine (Compound) downregulates PIN1 (Gene) and PIN1 (Gene) regulates RHOA (Gene) and RHOA (Gene) is upregulated by Terbinafine (Compound)