DDInter1888 DDInter593
An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit inefficiently, in mammals.
Doxepin is a psychotropic agent with antidepressant and anxiolytic properties. It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to [cidoxepin]. Doxepin commonly produces a 5:1 (E):(Z) racemic mixture. In a strict sense, doxepin is not a tricyclic antidepressant but it is commonly associated with the class since it shares a lot of properties with members of the drug family including [amitriptyline], [clomipramine], [desipramine], [imipramine], [nortriptyline], [protriptyline] and [trimipramine]. Doxepin was developed by Pfizer and FDA approved in 1969 as an antidepressant. However, in 2010 it was approved for the treatment of insomnia. The latter indication was presented by Pernix Therapeutics.
Tryptophan {u} (Compound) resembles {v} (Compound) Levodopa
Levodopa {u} may cause a minor interaction that can limit clinical effects when taken with {v} Doxepin
Tryptophan {u} (Compound) resembles {v} (Compound) Oxitriptan
Oxitriptan {u} may lead to a major life threatening interaction when taken with {v} Doxepin
Tryptophan {u} (Compound) resembles {v} (Compound) Levodopa
Levodopa {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Promethazine
Promethazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Doxepin
Tryptophan {u} (Compound) resembles {v} (Compound) L-Phenylalanine
L-Phenylalanine {u} (Compound) resembles {v} (Compound) Oxitriptan
Oxitriptan {u} may lead to a major life threatening interaction when taken with {v} Doxepin
Tryptophan {u} (Compound) resembles {v} (Compound) Oxitriptan
Oxitriptan {u} (Compound) resembles {v} (Compound) Levodopa
Levodopa {u} may cause a minor interaction that can limit clinical effects when taken with {v} Doxepin
Tryptophan {u} (Compound) resembles {v} (Compound) Levodopa
Levodopa {u} (Compound) binds {v} (Gene) DRD2
DRD2 {u} (Gene) is bound by {v} (Compound) Doxepin
Tryptophan {u} (Compound) resembles {v} (Compound) L-Histidine
L-Histidine {u} (Compound) resembles {v} (Compound) Oxitriptan
Oxitriptan {u} may lead to a major life threatening interaction when taken with {v} Doxepin
Tryptophan {u} (Compound) resembles {v} (Compound) Oxitriptan
Oxitriptan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ifosfamide
Ifosfamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Doxepin
Tryptophan {u} (Compound) resembles {v} (Compound) L-Tyrosine
L-Tyrosine {u} (Compound) resembles {v} (Compound) Liothyronine
Liothyronine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Doxepin
Tryptophan {u} (Compound) resembles {v} (Compound) L-Histidine
L-Histidine {u} (Compound) resembles {v} (Compound) Levodopa
Levodopa {u} may cause a minor interaction that can limit clinical effects when taken with {v} Doxepin
Tryptophan (Compound) resembles Levodopa (Compound) and Levodopa may cause a minor interaction that can limit clinical effects when taken with Doxepin
Tryptophan (Compound) resembles Oxitriptan (Compound) and Oxitriptan may lead to a major life threatening interaction when taken with Doxepin
Tryptophan (Compound) resembles Levodopa (Compound) and Levodopa may cause a moderate interaction that could exacerbate diseases when taken with Promethazine and Promethazine may cause a moderate interaction that could exacerbate diseases when taken with Doxepin
Tryptophan (Compound) resembles L-Phenylalanine (Compound) and L-Phenylalanine (Compound) resembles Oxitriptan (Compound) and Oxitriptan may lead to a major life threatening interaction when taken with Doxepin
Tryptophan (Compound) resembles Oxitriptan (Compound) and Oxitriptan (Compound) resembles Levodopa (Compound) and Levodopa may cause a minor interaction that can limit clinical effects when taken with Doxepin
Tryptophan (Compound) resembles Levodopa (Compound) and Levodopa (Compound) binds DRD2 (Gene) and DRD2 (Gene) is bound by Doxepin (Compound)
Tryptophan (Compound) resembles L-Histidine (Compound) and L-Histidine (Compound) resembles Oxitriptan (Compound) and Oxitriptan may lead to a major life threatening interaction when taken with Doxepin
Tryptophan (Compound) resembles Oxitriptan (Compound) and Oxitriptan may cause a moderate interaction that could exacerbate diseases when taken with Ifosfamide and Ifosfamide may cause a moderate interaction that could exacerbate diseases when taken with Doxepin
Tryptophan (Compound) resembles L-Tyrosine (Compound) and L-Tyrosine (Compound) resembles Liothyronine (Compound) and Liothyronine may cause a moderate interaction that could exacerbate diseases when taken with Doxepin
Tryptophan (Compound) resembles L-Histidine (Compound) and L-Histidine (Compound) resembles Levodopa (Compound) and Levodopa may cause a minor interaction that can limit clinical effects when taken with Doxepin