DDInter948 DDInter157
Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration . It was initially approved by the FDA in 1991 . It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used instead of other macrolides for some sexually transmitted and enteric infections. It is structurally related to erythromycin . Azithromycin [9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin] is a part of the _azalide_ subclass of macrolides, and contains a 15-membered ring, with a methyl-substituted nitrogen instead of a carbonyl group at the 9a position on the aglycone ring, which allows for the prevention of its metabolism. This differentiates azithromycin from other types of macrolides . In March 2020, a small study was funded by the French government to investigate the treatment of COVID-19 with a combination of azithromycin and the anti-malaria drug [hydroxychloroquine]. The results were positive, all patients taking the combination were virologically cured within 6 days of treatment, however, larger studies are required.
Azithromycin {u} (Compound) resembles {v} (Compound) Telithromycin
Azithromycin {u} (Compound) resembles {v} (Compound) Dirithromycin
Azithromycin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clarithromycin
Azithromycin {u} (Compound) binds {v} (Gene) CYP3A4
Azithromycin {u} (Compound) upregulates {v} (Gene) CDH3
Azithromycin {u} (Compound) is included by {v} (Pharmacologic Class) Macrolides
Azithromycin {u} (Compound) downregulates {v} (Gene) TSTA3
Azithromycin {u} (Compound) causes {v} (Side Effect) Face oedema
Azithromycin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Naloxegol
Azithromycin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Asparaginase Escherichia coli
Azithromycin (Compound) resembles Telithromycin (Compound)
Azithromycin (Compound) resembles Dirithromycin (Compound)
Azithromycin may cause a moderate interaction that could exacerbate diseases when taken with Clarithromycin
Azithromycin (Compound) binds CYP3A4 (Gene)
Azithromycin (Compound) upregulates CDH3 (Gene)
Azithromycin (Compound) is included by Macrolides (Pharmacologic Class)
Azithromycin (Compound) downregulates TSTA3 (Gene)
Azithromycin (Compound) causes Face oedema (Side Effect)
Azithromycin may cause a minor interaction that can limit clinical effects when taken with Naloxegol
Azithromycin may cause a moderate interaction that could exacerbate diseases when taken with Asparaginase Escherichia coli