DDInter1822 DDInter1464
Aminoglycosides, many of which are derived directly from _Streptomyces_ spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic _Pseudomonas aeruginosa_ infections in cystic fibrosis patients, as _P. aeruginosa_ is notoriously inherently resistant to many antibiotics.[A232294, A232299, L32739] However, tobramycin can also be administered intravenously and topically to treat a variety of infections caused by susceptible bacteria.[L32744, L32749] Its use is limited in some cases by characteristic toxicities such as nephrotoxicity and ototoxicity, yet it remains a valuable option in the face of growing resistance to front-line antibiotics such as β-lactams and cephalosporins.[A232294, A232349, L
Picosulfuric acid is found in laxative products. Sodium picosulfate is a used to treat constipation or induce colon cleansing to prepare the large bowels before colonoscopy or surgery. The combination product containing sodium picosulfate and magnesium citrate was introduced to the Canadian market in 2005 and has been used in European countries for many years.
Tobramycin {u} (Compound) resembles {v} (Compound) Neomycin
Neomycin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Picosulfuric acid
Tobramycin {u} (Compound) resembles {v} (Compound) Neomycin
Neomycin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Digoxin
Digoxin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Picosulfuric acid
Tobramycin {u} (Compound) resembles {v} (Compound) Paromomycin
Paromomycin {u} (Compound) resembles {v} (Compound) Lactulose
Lactulose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Picosulfuric acid
Tobramycin {u} (Compound) resembles {v} (Compound) Lactulose
Lactulose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methylcellulose
Methylcellulose {u} may cause a minor interaction that can limit clinical effects when taken with {v} Picosulfuric acid
Tobramycin {u} (Compound) resembles {v} (Compound) Neomycin
Neomycin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cefoxitin
Cefoxitin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Picosulfuric acid
Tobramycin {u} (Compound) resembles {v} (Compound) Kanamycin
Kanamycin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Piroxicam
Piroxicam {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Picosulfuric acid
Tobramycin {u} (Compound) resembles {v} (Compound) Lactulose
Lactulose {u} may cause a minor interaction that can limit clinical effects when taken with {v} Linaclotide
Linaclotide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Picosulfuric acid
Tobramycin {u} (Compound) resembles {v} (Compound) Arbekacin
Arbekacin {u} (Compound) resembles {v} (Compound) Kanamycin
Kanamycin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Picosulfuric acid
Tobramycin {u} (Compound) resembles {v} (Compound) Lactulose
Lactulose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Entrectinib
Entrectinib {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Picosulfuric acid
Tobramycin {u} (Compound) is included by {v} (Pharmacologic Class) Aminoglycosides
Aminoglycosides {u} (Pharmacologic Class) includes {v} (Compound) Neomycin
Neomycin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Picosulfuric acid
Tobramycin (Compound) resembles Neomycin (Compound) and Neomycin may cause a moderate interaction that could exacerbate diseases when taken with Picosulfuric acid
Tobramycin (Compound) resembles Neomycin (Compound) and Neomycin may cause a minor interaction that can limit clinical effects when taken with Digoxin and Digoxin may cause a minor interaction that can limit clinical effects when taken with Picosulfuric acid
Tobramycin (Compound) resembles Paromomycin (Compound) and Paromomycin (Compound) resembles Lactulose (Compound) and Lactulose may cause a moderate interaction that could exacerbate diseases when taken with Picosulfuric acid
Tobramycin (Compound) resembles Lactulose (Compound) and Lactulose may cause a moderate interaction that could exacerbate diseases when taken with Methylcellulose and Methylcellulose may cause a minor interaction that can limit clinical effects when taken with Picosulfuric acid
Tobramycin (Compound) resembles Neomycin (Compound) and Neomycin may cause a moderate interaction that could exacerbate diseases when taken with Cefoxitin and Cefoxitin may cause a moderate interaction that could exacerbate diseases when taken with Picosulfuric acid
Tobramycin (Compound) resembles Kanamycin (Compound) and Kanamycin may cause a moderate interaction that could exacerbate diseases when taken with Piroxicam and Piroxicam may cause a moderate interaction that could exacerbate diseases when taken with Picosulfuric acid
Tobramycin (Compound) resembles Lactulose (Compound) and Lactulose may cause a minor interaction that can limit clinical effects when taken with Linaclotide and Linaclotide may cause a minor interaction that can limit clinical effects when taken with Picosulfuric acid
Tobramycin (Compound) resembles Arbekacin (Compound) and Arbekacin (Compound) resembles Kanamycin (Compound) and Kanamycin may cause a moderate interaction that could exacerbate diseases when taken with Picosulfuric acid
Tobramycin (Compound) resembles Lactulose (Compound) and Lactulose may cause a moderate interaction that could exacerbate diseases when taken with Entrectinib and Entrectinib may cause a moderate interaction that could exacerbate diseases when taken with Picosulfuric acid
Tobramycin (Compound) is included by Aminoglycosides (Pharmacologic Class) and Aminoglycosides (Pharmacologic Class) includes Neomycin (Compound) and Neomycin may cause a moderate interaction that could exacerbate diseases when taken with Picosulfuric acid