DDInter699 DDInter690
Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.
Etodolac {u} (Compound) binds {v} (Gene) CYP2C9
CYP2C9 {u} (Gene) is bound by {v} (Compound) Ethanol
Etodolac {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clopidogrel
Clopidogrel {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Ethanol
Etodolac {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ticlopidine
Ticlopidine {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Ethanol
Etodolac {u} may lead to a major life threatening interaction when taken with {v} Regorafenib
Regorafenib {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Ethanol
Etodolac {u} may cause a minor interaction that can limit clinical effects when taken with {v} Famotidine
Famotidine {u} (Compound) binds {v} (Gene) CYP2C19
CYP2C19 {u} (Gene) is bound by {v} (Compound) Ethanol
Etodolac {u} may lead to a major life threatening interaction when taken with {v} Warfarin
Warfarin {u} (Compound) binds {v} (Gene) CYP2C19
CYP2C19 {u} (Gene) is bound by {v} (Compound) Ethanol
Etodolac {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cimetidine
Cimetidine {u} (Compound) binds {v} (Gene) CYP2C19
CYP2C19 {u} (Gene) is bound by {v} (Compound) Ethanol
Etodolac {u} (Compound) binds {v} (Gene) UGT2B7
UGT2B7 {u} (Gene) interacts with {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Ethanol
Etodolac {u} (Compound) upregulates {v} (Gene) SERPINA3
SERPINA3 {u} (Gene) interacts with {v} (Gene) ADH1B
ADH1B {u} (Gene) is bound by {v} (Compound) Ethanol
Etodolac {u} (Compound) upregulates {v} (Gene) MAL
MAL {u} (Gene) is regulated by {v} (Gene) CYP2E1
CYP2E1 {u} (Gene) is bound by {v} (Compound) Ethanol
Etodolac (Compound) binds CYP2C9 (Gene) and CYP2C9 (Gene) is bound by Ethanol (Compound)
Etodolac may cause a moderate interaction that could exacerbate diseases when taken with Clopidogrel and Clopidogrel (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Ethanol (Compound)
Etodolac may cause a moderate interaction that could exacerbate diseases when taken with Ticlopidine and Ticlopidine (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Ethanol (Compound)
Etodolac may lead to a major life threatening interaction when taken with Regorafenib and Regorafenib (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Ethanol (Compound)
Etodolac may cause a minor interaction that can limit clinical effects when taken with Famotidine and Famotidine (Compound) binds CYP2C19 (Gene) and CYP2C19 (Gene) is bound by Ethanol (Compound)
Etodolac may lead to a major life threatening interaction when taken with Warfarin and Warfarin (Compound) binds CYP2C19 (Gene) and CYP2C19 (Gene) is bound by Ethanol (Compound)
Etodolac may cause a minor interaction that can limit clinical effects when taken with Cimetidine and Cimetidine (Compound) binds CYP2C19 (Gene) and CYP2C19 (Gene) is bound by Ethanol (Compound)
Etodolac (Compound) binds UGT2B7 (Gene) and UGT2B7 (Gene) interacts with CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Ethanol (Compound)
Etodolac (Compound) upregulates SERPINA3 (Gene) and SERPINA3 (Gene) interacts with ADH1B (Gene) and ADH1B (Gene) is bound by Ethanol (Compound)
Etodolac (Compound) upregulates MAL (Gene) and MAL (Gene) is regulated by CYP2E1 (Gene) and CYP2E1 (Gene) is bound by Ethanol (Compound)