DDInter1837 DDInter1610
Toremifene is a selective estrogen receptor modulator (SERM) and a nonsteroidal antiestrogen used to treat estrogen receptor positive breast cancer. Like [tamoxifen], toremifene is part of the first-generation triphenylethylene derivative chemical class of SERMs. Toremifene possesses tissue-specific actions: it has estrogenic (agonist) activity on the cardiovascular system and on bone tissue and it has weak estrogenic effects on uterine tissue, however, it also has antiestrogenic (estrogen-antagonist) activity on breast tissue.
Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type. Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase.
Toremifene {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Rivastigmine
Toremifene {u} (Compound) upregulates {v} (Gene) GHR
GHR {u} (Gene) is upregulated by {v} (Compound) Rivastigmine
Toremifene {u} (Compound) downregulates {v} (Gene) CDC20
CDC20 {u} (Gene) is downregulated by {v} (Compound) Rivastigmine
Toremifene {u} (Compound) upregulates {v} (Gene) STXBP2
STXBP2 {u} (Gene) is downregulated by {v} (Compound) Rivastigmine
Toremifene {u} (Compound) causes {v} (Side Effect) Pruritus
Pruritus {u} (Side Effect) is caused by {v} (Compound) Rivastigmine
Toremifene {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Pyridostigmine
Pyridostigmine {u} (Compound) resembles {v} (Compound) Rivastigmine
Toremifene {u} (Compound) upregulates {v} (Gene) GHR
GHR {u} (Gene) interacts with {v} (Gene) STUB1
STUB1 {u} (Gene) is downregulated by {v} (Compound) Rivastigmine
Toremifene {u} (Compound) upregulates {v} (Gene) ST6GALNAC2
ST6GALNAC2 {u} (Gene) is regulated by {v} (Gene) GDPD5
GDPD5 {u} (Gene) is upregulated by {v} (Compound) Rivastigmine
Toremifene {u} (Compound) downregulates {v} (Gene) CDC20
CDC20 {u} (Gene) is regulated by {v} (Gene) GDPD5
GDPD5 {u} (Gene) is upregulated by {v} (Compound) Rivastigmine
Toremifene {u} (Compound) causes {v} (Side Effect) Pruritus
Pruritus {u} (Side Effect) is caused by {v} (Compound) Tapentadol
Tapentadol {u} (Compound) resembles {v} (Compound) Rivastigmine
Toremifene (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Rivastigmine (Compound)
Toremifene (Compound) upregulates GHR (Gene) and GHR (Gene) is upregulated by Rivastigmine (Compound)
Toremifene (Compound) downregulates CDC20 (Gene) and CDC20 (Gene) is downregulated by Rivastigmine (Compound)
Toremifene (Compound) upregulates STXBP2 (Gene) and STXBP2 (Gene) is downregulated by Rivastigmine (Compound)
Toremifene (Compound) causes Pruritus (Side Effect) and Pruritus (Side Effect) is caused by Rivastigmine (Compound)
Toremifene (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Pyridostigmine (Compound) and Pyridostigmine (Compound) resembles Rivastigmine (Compound)
Toremifene (Compound) upregulates GHR (Gene) and GHR (Gene) interacts with STUB1 (Gene) and STUB1 (Gene) is downregulated by Rivastigmine (Compound)
Toremifene (Compound) upregulates ST6GALNAC2 (Gene) and ST6GALNAC2 (Gene) is regulated by GDPD5 (Gene) and GDPD5 (Gene) is upregulated by Rivastigmine (Compound)
Toremifene (Compound) downregulates CDC20 (Gene) and CDC20 (Gene) is regulated by GDPD5 (Gene) and GDPD5 (Gene) is upregulated by Rivastigmine (Compound)
Toremifene (Compound) causes Pruritus (Side Effect) and Pruritus (Side Effect) is caused by Tapentadol (Compound) and Tapentadol (Compound) resembles Rivastigmine (Compound)