DDInter763 DDInter698
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis. Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen.
Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid]. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and [risedronic acid]. Etidronic acid was granted FDA approval on 1 September 1977.
Flurbiprofen {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Risedronic acid
Risedronic acid {u} (Compound) resembles {v} (Compound) Etidronic acid
Flurbiprofen {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ibandronate
Ibandronate {u} (Compound) resembles {v} (Compound) Etidronic acid
Flurbiprofen {u} (Compound) downregulates {v} (Gene) ACAT2
ACAT2 {u} (Gene) is downregulated by {v} (Compound) Etidronic acid
Flurbiprofen {u} (Compound) causes {v} (Side Effect) Confusional state
Confusional state {u} (Side Effect) is caused by {v} (Compound) Etidronic acid
Flurbiprofen {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Risedronic acid
Risedronic acid {u} (Compound) resembles {v} (Compound) Ibandronate
Ibandronate {u} (Compound) resembles {v} (Compound) Etidronic acid
Flurbiprofen {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ibandronate
Ibandronate {u} (Compound) resembles {v} (Compound) Risedronic acid
Risedronic acid {u} (Compound) resembles {v} (Compound) Etidronic acid
Flurbiprofen {u} (Compound) downregulates {v} (Gene) ACAT2
ACAT2 {u} (Gene) regulates {v} (Gene) SERPINA3
SERPINA3 {u} (Gene) is upregulated by {v} (Compound) Etidronic acid
Flurbiprofen {u} (Compound) causes {v} (Side Effect) Confusional state
Confusional state {u} (Side Effect) is caused by {v} (Compound) Pamidronic acid
Pamidronic acid {u} (Compound) resembles {v} (Compound) Etidronic acid
Flurbiprofen {u} (Compound) binds {v} (Gene) PTGS2
PTGS2 {u} (Gene) is bound by {v} (Compound) Risedronic acid
Risedronic acid {u} (Compound) resembles {v} (Compound) Etidronic acid
Flurbiprofen {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ibandronate
Ibandronate {u} (Compound) resembles {v} (Compound) Pamidronic acid
Pamidronic acid {u} (Compound) resembles {v} (Compound) Etidronic acid
Flurbiprofen may cause a moderate interaction that could exacerbate diseases when taken with Risedronic acid and Risedronic acid (Compound) resembles Etidronic acid (Compound)
Flurbiprofen may cause a moderate interaction that could exacerbate diseases when taken with Ibandronate and Ibandronate (Compound) resembles Etidronic acid (Compound)
Flurbiprofen (Compound) downregulates ACAT2 (Gene) and ACAT2 (Gene) is downregulated by Etidronic acid (Compound)
Flurbiprofen (Compound) causes Confusional state (Side Effect) and Confusional state (Side Effect) is caused by Etidronic acid (Compound)
Flurbiprofen may cause a moderate interaction that could exacerbate diseases when taken with Risedronic acid and Risedronic acid (Compound) resembles Ibandronate (Compound) and Ibandronate (Compound) resembles Etidronic acid (Compound)
Flurbiprofen may cause a moderate interaction that could exacerbate diseases when taken with Ibandronate and Ibandronate (Compound) resembles Risedronic acid (Compound) and Risedronic acid (Compound) resembles Etidronic acid (Compound)
Flurbiprofen (Compound) downregulates ACAT2 (Gene) and ACAT2 (Gene) regulates SERPINA3 (Gene) and SERPINA3 (Gene) is upregulated by Etidronic acid (Compound)
Flurbiprofen (Compound) causes Confusional state (Side Effect) and Confusional state (Side Effect) is caused by Pamidronic acid (Compound) and Pamidronic acid (Compound) resembles Etidronic acid (Compound)
Flurbiprofen (Compound) binds PTGS2 (Gene) and PTGS2 (Gene) is bound by Risedronic acid (Compound) and Risedronic acid (Compound) resembles Etidronic acid (Compound)
Flurbiprofen may cause a moderate interaction that could exacerbate diseases when taken with Ibandronate and Ibandronate (Compound) resembles Pamidronic acid (Compound) and Pamidronic acid (Compound) resembles Etidronic acid (Compound)