DDInter916 DDInter278
The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension. Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. Treatment for hypertension should include a number of lifestyle changes (ie. reduced sodium intake) along with pharmacotherapy - it should be noted that treatment with several antihypertensive agents may be required in order to achieve blood pressure targets. Thiazide-like diuretics such as indapamide are a valuable tool for the treatment of hypertension and continue to grow in popularity, falling behind only ACE inhibitors in terms of prescription frequency. When compared to [hydrochlorothiazide] (another commonly prescribed diuretic), indapamide has been shown to be superior at lowering systolic blood pressure, reducing left ventricular mass index, lowering oxidative stress, inhibiting platelet aggregation, and reducing microalbuminuria associated with diabetes. Interestingly,
Calcium lactate is a salt that consists of two lactate anions for each calcium cation (Ca2+). It is prepared commercially by the neutralization of lactic acid with calcium carbonate or calcium hydroxide. Approved by the FDA as a direct food substance affirmed as generally recognized as safe, calcium lactate is used as a firming agent, flavoring agent, leavening agent, stabilizer, and thickener . Calcium lactate is also found in daily dietary supplements as a source of calcium. It is also available in various hydrate forms, where calcium lactate pentahydrate is the most common.
Indapamide {u} (Compound) resembles {v} (Compound) Metolazone
Indapamide {u} (Compound) resembles {v} (Compound) Oxcarbazepine
Indapamide {u} (Compound) treats {v} (Disease) hypertension
Indapamide {u} (Compound) binds {v} (Gene) CA5A
Indapamide {u} (Compound) is included by {v} (Pharmacologic Class) Increased Diuresis
Indapamide {u} (Compound) causes {v} (Side Effect) Blister
Indapamide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Mepenzolate
Indapamide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Atropine
Indapamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Calcifediol
Indapamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Saxagliptin
Indapamide (Compound) resembles Metolazone (Compound)
Indapamide (Compound) resembles Oxcarbazepine (Compound)
Indapamide (Compound) treats hypertension (Disease)
Indapamide (Compound) binds CA5A (Gene)
Indapamide (Compound) is included by Increased Diuresis (Pharmacologic Class)
Indapamide (Compound) causes Blister (Side Effect)
Indapamide may cause a minor interaction that can limit clinical effects when taken with Mepenzolate
Indapamide may cause a minor interaction that can limit clinical effects when taken with Atropine
Indapamide may cause a moderate interaction that could exacerbate diseases when taken with Calcifediol
Indapamide may cause a moderate interaction that could exacerbate diseases when taken with Saxagliptin