DDInter1239 DDInter1180
An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder. Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors. It has only low to moderate affinity for cholinergic and alpha-adrenergic receptors. Some electrophysiologic data from animals indicate that molindone has certain characteristics that resemble those of clozapine. (From AMA Drug Evaluations Annual, 1994, p283)
Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Molindone {u} (Compound) binds {v} (Gene) DRD2
Molindone {u} (Compound) upregulates {v} (Gene) TSKU
Molindone {u} (Compound) downregulates {v} (Gene) UGDH
Molindone {u} (Compound) causes {v} (Side Effect) Movements involuntary
Molindone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Brompheniramine
Molindone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Picosulfuric acid
Molindone {u} may lead to a major life threatening interaction when taken with {v} Iohexol
Molindone (Compound) binds DRD2 (Gene)
Molindone (Compound) upregulates TSKU (Gene)
Molindone (Compound) downregulates UGDH (Gene)
Molindone (Compound) causes Movements involuntary (Side Effect)
Molindone may cause a moderate interaction that could exacerbate diseases when taken with Brompheniramine
Molindone may cause a moderate interaction that could exacerbate diseases when taken with Picosulfuric acid
Molindone may lead to a major life threatening interaction when taken with Iohexol