DDInter717 DDInter258
Dravet syndrome is a pediatric encephalopathy that typically manifests within the first year of life following exposure to elevated temperatures. It is characterized by recurrent pharmacoresistant seizures, which increase in frequency and severity with disease progression. Concomitantly with these seizures, patients typically display delayed development and neurocognitive impairment.[A214694, A214709, A214712, A214715] Fenfluramine is a serotonergic phenethylamine originally used as an appetite suppressant until concerns regarding cardiotoxicity in obese patients lead to its withdrawal from the market in 1997.[A214694, A214718, A11906] Through its ability to modulate neurotransmission, fenfluramine has reemerged as an effective therapy against pharmacoresistant seizures, such as those involved in Dravet syndrome.[A214688, A214691, A214700] Fenfluramine was granted initial FDA approval in 1973 prior to its withdrawal
A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Fenfluramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dezocine
Dezocine {u} (Compound) resembles {v} (Compound) Butorphanol
Fenfluramine {u} may lead to a major life threatening interaction when taken with {v} Pentazocine
Pentazocine {u} (Compound) resembles {v} (Compound) Butorphanol
Fenfluramine {u} may lead to a major life threatening interaction when taken with {v} Dextromethorphan
Dextromethorphan {u} (Compound) resembles {v} (Compound) Butorphanol
Fenfluramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dezocine
Dezocine {u} (Compound) resembles {v} (Compound) Levallorphan
Levallorphan {u} (Compound) resembles {v} (Compound) Butorphanol
Fenfluramine {u} may lead to a major life threatening interaction when taken with {v} Pentazocine
Pentazocine {u} (Compound) resembles {v} (Compound) Levallorphan
Levallorphan {u} (Compound) resembles {v} (Compound) Butorphanol
Fenfluramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nalbuphine
Nalbuphine {u} (Compound) resembles {v} (Compound) and {u} may lead to a major life threatening interaction when taken with {v} Naltrexone
Naltrexone {u} (Compound) resembles {v} (Compound) Butorphanol
Fenfluramine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Naloxone
Naloxone {u} (Compound) resembles {v} (Compound) Levallorphan
Levallorphan {u} (Compound) resembles {v} (Compound) Butorphanol
Fenfluramine {u} may lead to a major life threatening interaction when taken with {v} Dextromethorphan
Dextromethorphan {u} (Compound) resembles {v} (Compound) Levallorphan
Levallorphan {u} (Compound) resembles {v} (Compound) Butorphanol
Fenfluramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dezocine
Dezocine {u} may lead to a major life threatening interaction when taken with {v} Naltrexone
Naltrexone {u} (Compound) resembles {v} (Compound) Butorphanol
Fenfluramine {u} may lead to a major life threatening interaction when taken with {v} Pentazocine
Pentazocine {u} may lead to a major life threatening interaction when taken with {v} Naltrexone
Naltrexone {u} (Compound) resembles {v} (Compound) Butorphanol
Fenfluramine may cause a moderate interaction that could exacerbate diseases when taken with Dezocine and Dezocine (Compound) resembles Butorphanol (Compound)
Fenfluramine may lead to a major life threatening interaction when taken with Pentazocine and Pentazocine (Compound) resembles Butorphanol (Compound)
Fenfluramine may lead to a major life threatening interaction when taken with Dextromethorphan and Dextromethorphan (Compound) resembles Butorphanol (Compound)
Fenfluramine may cause a moderate interaction that could exacerbate diseases when taken with Dezocine and Dezocine (Compound) resembles Levallorphan (Compound) and Levallorphan (Compound) resembles Butorphanol (Compound)
Fenfluramine may lead to a major life threatening interaction when taken with Pentazocine and Pentazocine (Compound) resembles Levallorphan (Compound) and Levallorphan (Compound) resembles Butorphanol (Compound)
Fenfluramine may cause a moderate interaction that could exacerbate diseases when taken with Nalbuphine and Nalbuphine (Compound) resembles Naltrexone (Compound) and Nalbuphine may lead to a major life threatening interaction when taken with Naltrexone and Naltrexone (Compound) resembles Butorphanol (Compound)
Fenfluramine may cause a minor interaction that can limit clinical effects when taken with Naloxone and Naloxone (Compound) resembles Levallorphan (Compound) and Levallorphan (Compound) resembles Butorphanol (Compound)
Fenfluramine may lead to a major life threatening interaction when taken with Dextromethorphan and Dextromethorphan (Compound) resembles Levallorphan (Compound) and Levallorphan (Compound) resembles Butorphanol (Compound)
Fenfluramine may cause a moderate interaction that could exacerbate diseases when taken with Dezocine and Dezocine may lead to a major life threatening interaction when taken with Naltrexone and Naltrexone (Compound) resembles Butorphanol (Compound)
Fenfluramine may lead to a major life threatening interaction when taken with Pentazocine and Pentazocine may lead to a major life threatening interaction when taken with Naltrexone and Naltrexone (Compound) resembles Butorphanol (Compound)