DDInter856 DDInter322
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated hepar
Cefoperazone is a semisynthetic broad-spectrum cephalosporin proposed to be effective against <i>Pseudomonas</i> infections. It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections caused by susceptible organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and bacterial septicemia. While its clinical use has been discontinued in the U.S., cefoperazone is available in several European countries most commonly under the product name, Sulperazon.
Cefoperazone {u} (Compound) resembles {v} (Compound) Cefpiramide
Cefoperazone {u} (Compound) resembles {v} (Compound) Cefmetazole
Cefoperazone {u} (Compound) binds {v} (Gene) SLC22A7
Cefoperazone {u} (Compound) is included by {v} (Pharmacologic Class) Cephalosporins
Cefoperazone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Chloramphenicol
Cefoperazone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Picosulfuric acid
Cefoperazone (Compound) resembles Cefpiramide (Compound)
Cefoperazone (Compound) resembles Cefmetazole (Compound)
Cefoperazone (Compound) binds SLC22A7 (Gene)
Cefoperazone (Compound) is included by Cephalosporins (Pharmacologic Class)
Cefoperazone may cause a moderate interaction that could exacerbate diseases when taken with Chloramphenicol
Cefoperazone may cause a moderate interaction that could exacerbate diseases when taken with Picosulfuric acid