DDInter1886 DDInter1544
Trospium is an antispasmodic agent used to treat the symptoms of overactive bladder, a condition that causes the bladder muscles to contract uncontrollably. An overactive bladder leads to an increased urge to urinate, frequent urination, and sometimes, loss of control over urination. Trospium is manufactured by _Indevus Pharmaceutical Inc._ and was granted FDA approval in 2007.
Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties. The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies. Prucalopride was developed by Shire Development LLC and approved for use in Europe in 2009, in Canada on December 7, 2011 and by the FDA on December 17, 2018.
Trospium {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mepenzolate
Trospium {u} (Compound) resembles {v} (Compound) Homatropine Methylbromide
Trospium {u} (Compound) binds {v} (Gene) CHRM3
Trospium {u} (Compound) is included by {v} (Pharmacologic Class) Cholinergic Muscarinic Antagonists
Trospium {u} (Compound) causes {v} (Side Effect) Delirium
Trospium {u} may cause a minor interaction that can limit clinical effects when taken with {v} Polythiazide
Trospium {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Botulinum toxin type A
Trospium {u} may lead to a major life threatening interaction when taken with {v} Potassium chloride
Trospium {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Darifenacin
Trospium may cause a moderate interaction that could exacerbate diseases when taken with Mepenzolate
Trospium (Compound) resembles Homatropine Methylbromide (Compound)
Trospium (Compound) binds CHRM3 (Gene)
Trospium (Compound) is included by Cholinergic Muscarinic Antagonists (Pharmacologic Class)
Trospium (Compound) causes Delirium (Side Effect)
Trospium may cause a minor interaction that can limit clinical effects when taken with Polythiazide
Trospium may cause a moderate interaction that could exacerbate diseases when taken with Botulinum toxin type A
Trospium may lead to a major life threatening interaction when taken with Potassium chloride
Trospium (Compound) resembles Darifenacin (Compound) and Trospium may cause a moderate interaction that could exacerbate diseases when taken with Darifenacin