DDInter1176 DDInter915
An alpha-adrenergic agonist that causes prolonged peripheral vasoconstriction. It has little if any direct effect on the central nervous system.
Indacaterol is a novel, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist developed for Novartis for the once-daily management of asthma and chronic obstructive pulmonary disease. It was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011. It is marketed in Europe as Onbrez and in America as Arcapta Neohaler. Indacaterol is provided as its maleate salt form. Indacaterol is also a chiral molecule but only the pure R-enantiomer is dispensed.
Methoxamine {u} (Compound) resembles {v} (Compound) Midodrine
Midodrine {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Indacaterol
Methoxamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sitagliptin
Sitagliptin {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Indacaterol
Methoxamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenylpropanolamine
Phenylpropanolamine {u} (Compound) binds {v} (Gene) ADRB2
ADRB2 {u} (Gene) is bound by {v} (Compound) Indacaterol
Methoxamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Glimepiride
Glimepiride {u} (Compound) causes {v} (Side Effect) Angina pectoris
Angina pectoris {u} (Side Effect) is caused by {v} (Compound) Indacaterol
Methoxamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sitagliptin
Sitagliptin {u} (Compound) causes {v} (Side Effect) Cardiac disorder
Cardiac disorder {u} (Side Effect) is caused by {v} (Compound) Indacaterol
Methoxamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Salmeterol
Salmeterol {u} (Compound) treats {v} (Disease) asthma
asthma {u} (Disease) is treated by {v} (Compound) Indacaterol
Methoxamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Salmeterol
Salmeterol {u} (Compound) is included by {v} (Pharmacologic Class) Adrenergic beta2-Agonists
Adrenergic beta2-Agonists {u} (Pharmacologic Class) includes {v} (Compound) Indacaterol
Methoxamine {u} may lead to a major life threatening interaction when taken with {v} Doxepin
Doxepin {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Indacaterol
Methoxamine {u} may lead to a major life threatening interaction when taken with {v} Cocaine
Cocaine {u} (Compound) causes {v} (Side Effect) Tremor
Tremor {u} (Side Effect) is caused by {v} (Compound) Indacaterol
Methoxamine (Compound) resembles Midodrine (Compound) and Midodrine (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Indacaterol (Compound)
Methoxamine may cause a moderate interaction that could exacerbate diseases when taken with Sitagliptin and Sitagliptin (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Indacaterol (Compound)
Methoxamine may cause a moderate interaction that could exacerbate diseases when taken with Phenylpropanolamine and Phenylpropanolamine (Compound) binds ADRB2 (Gene) and ADRB2 (Gene) is bound by Indacaterol (Compound)
Methoxamine may cause a moderate interaction that could exacerbate diseases when taken with Glimepiride and Glimepiride (Compound) causes Angina pectoris (Side Effect) and Angina pectoris (Side Effect) is caused by Indacaterol (Compound)
Methoxamine may cause a moderate interaction that could exacerbate diseases when taken with Sitagliptin and Sitagliptin (Compound) causes Cardiac disorder (Side Effect) and Cardiac disorder (Side Effect) is caused by Indacaterol (Compound)
Methoxamine may cause a moderate interaction that could exacerbate diseases when taken with Salmeterol and Salmeterol (Compound) treats asthma (Disease) and asthma (Disease) is treated by Indacaterol (Compound)
Methoxamine may cause a moderate interaction that could exacerbate diseases when taken with Salmeterol and Salmeterol (Compound) is included by Adrenergic beta2-Agonists (Pharmacologic Class) and Adrenergic beta2-Agonists (Pharmacologic Class) includes Indacaterol (Compound)
Methoxamine may lead to a major life threatening interaction when taken with Doxepin and Doxepin (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Indacaterol (Compound)
Methoxamine may lead to a major life threatening interaction when taken with Cocaine and Cocaine (Compound) causes Tremor (Side Effect) and Tremor (Side Effect) is caused by Indacaterol (Compound)