DDInter458 DDInter1135
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus _Beauveria nivea_. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
Cyclosporine {u} (Compound) binds {v} (Gene) SLC22A6
SLC22A6 {u} (Gene) is bound by {v} (Compound) Meclofenamic acid
Cyclosporine {u} (Compound) upregulates {v} (Gene) DMTF1
DMTF1 {u} (Gene) is upregulated by {v} (Compound) Meclofenamic acid
Cyclosporine {u} (Compound) causes {v} (Side Effect) Abdominal pain
Abdominal pain {u} (Side Effect) is caused by {v} (Compound) Meclofenamic acid
Cyclosporine {u} (Compound) binds {v} (Gene) SLC22A6
SLC22A6 {u} (Gene) is bound by {v} (Compound) Salicylic acid
Salicylic acid {u} (Compound) resembles {v} (Compound) Meclofenamic acid
Cyclosporine {u} (Compound) upregulates {v} (Gene) DMTF1
DMTF1 {u} (Gene) is upregulated by {v} (Compound) Niclosamide
Niclosamide {u} (Compound) resembles {v} (Compound) Meclofenamic acid
Cyclosporine {u} (Compound) causes {v} (Side Effect) Abdominal pain
Abdominal pain {u} (Side Effect) is caused by {v} (Compound) Salsalate
Salsalate {u} (Compound) resembles {v} (Compound) Meclofenamic acid
Cyclosporine {u} (Compound) causes {v} (Side Effect) Fatigue
Fatigue {u} (Side Effect) is caused by {v} (Compound) Cimetidine
Cimetidine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Meclofenamic acid
Cyclosporine {u} (Compound) causes {v} (Side Effect) Nocturia
Nocturia {u} (Side Effect) is caused by {v} (Compound) Glimepiride
Glimepiride {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Meclofenamic acid
Cyclosporine {u} (Compound) binds {v} (Gene) SLC22A6
SLC22A6 {u} (Gene) is bound by {v} (Compound) Acetylsalicylic acid
Acetylsalicylic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Meclofenamic acid
Cyclosporine {u} (Compound) upregulates {v} (Gene) DMTF1
DMTF1 {u} (Gene) is upregulated by {v} (Compound) Treprostinil
Treprostinil {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Meclofenamic acid
Cyclosporine (Compound) binds SLC22A6 (Gene) and SLC22A6 (Gene) is bound by Meclofenamic acid (Compound)
Cyclosporine (Compound) upregulates DMTF1 (Gene) and DMTF1 (Gene) is upregulated by Meclofenamic acid (Compound)
Cyclosporine (Compound) causes Abdominal pain (Side Effect) and Abdominal pain (Side Effect) is caused by Meclofenamic acid (Compound)
Cyclosporine (Compound) binds SLC22A6 (Gene) and SLC22A6 (Gene) is bound by Salicylic acid (Compound) and Salicylic acid (Compound) resembles Meclofenamic acid (Compound)
Cyclosporine (Compound) upregulates DMTF1 (Gene) and DMTF1 (Gene) is upregulated by Niclosamide (Compound) and Niclosamide (Compound) resembles Meclofenamic acid (Compound)
Cyclosporine (Compound) causes Abdominal pain (Side Effect) and Abdominal pain (Side Effect) is caused by Salsalate (Compound) and Salsalate (Compound) resembles Meclofenamic acid (Compound)
Cyclosporine (Compound) causes Fatigue (Side Effect) and Fatigue (Side Effect) is caused by Cimetidine (Compound) and Cimetidine may cause a minor interaction that can limit clinical effects when taken with Meclofenamic acid
Cyclosporine (Compound) causes Nocturia (Side Effect) and Nocturia (Side Effect) is caused by Glimepiride (Compound) and Glimepiride may cause a moderate interaction that could exacerbate diseases when taken with Meclofenamic acid
Cyclosporine (Compound) binds SLC22A6 (Gene) and SLC22A6 (Gene) is bound by Acetylsalicylic acid (Compound) and Acetylsalicylic acid may cause a moderate interaction that could exacerbate diseases when taken with Meclofenamic acid
Cyclosporine (Compound) upregulates DMTF1 (Gene) and DMTF1 (Gene) is upregulated by Treprostinil (Compound) and Treprostinil may cause a moderate interaction that could exacerbate diseases when taken with Meclofenamic acid