DDInter896 DDInter1845
Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine]. It is commonly extracted from plants in the _Solanaceae_ or nightshade family. Research into the action of hyoscyamine in published literature dates back to 1826. Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic properties.[L31548,L31553] Although hyoscyamine is marketed in the United States, it is not FDA approved.[L31548,L31553]
A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders (From AMA Drug Evaluations Annual, 1994, p311). Tranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine with the chiral centers both located on the cylopropane ring. An irreversible monoamine oxidase inhibitor that is used as an antidepressant (INN tranylcypromine).
Hyoscyamine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Phenelzine
Phenelzine {u} (Compound) resembles {v} (Compound) Tranylcypromine
Hyoscyamine {u} (Compound) causes {v} (Side Effect) Oedema
Oedema {u} (Side Effect) is caused by {v} (Compound) Tranylcypromine
Hyoscyamine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Phenelzine
Phenelzine {u} may lead to a major life threatening interaction when taken with {v} Phentermine
Phentermine {u} (Compound) resembles {v} (Compound) Tranylcypromine
Hyoscyamine {u} (Compound) causes {v} (Side Effect) Oedema
Oedema {u} (Side Effect) is caused by {v} (Compound) Phentermine
Phentermine {u} (Compound) resembles {v} (Compound) Tranylcypromine
Hyoscyamine {u} (Compound) causes {v} (Side Effect) Anxiety
Anxiety {u} (Side Effect) is caused by {v} (Compound) Dextroamphetamine
Dextroamphetamine {u} (Compound) resembles {v} (Compound) Tranylcypromine
Hyoscyamine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Phenelzine
Phenelzine {u} (Compound) resembles {v} (Compound) Dextroamphetamine
Dextroamphetamine {u} (Compound) resembles {v} (Compound) Tranylcypromine
Hyoscyamine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Phenelzine
Phenelzine {u} (Compound) resembles {v} (Compound) Phenol
Phenol {u} (Compound) resembles {v} (Compound) Tranylcypromine
Hyoscyamine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Phenelzine
Phenelzine {u} (Compound) resembles {v} (Compound) and {u} may lead to a major life threatening interaction when taken with {v} Phenylpropanolamine
Phenylpropanolamine {u} (Compound) resembles {v} (Compound) Tranylcypromine
Hyoscyamine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Phenelzine
Phenelzine {u} (Compound) binds {v} (Gene) CYP2C19
CYP2C19 {u} (Gene) is bound by {v} (Compound) Tranylcypromine
Hyoscyamine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Phenelzine
Phenelzine {u} (Compound) causes {v} (Side Effect) Oedema
Oedema {u} (Side Effect) is caused by {v} (Compound) Tranylcypromine
Hyoscyamine may cause a minor interaction that can limit clinical effects when taken with Phenelzine and Phenelzine (Compound) resembles Tranylcypromine (Compound)
Hyoscyamine (Compound) causes Oedema (Side Effect) and Oedema (Side Effect) is caused by Tranylcypromine (Compound)
Hyoscyamine may cause a minor interaction that can limit clinical effects when taken with Phenelzine and Phenelzine may lead to a major life threatening interaction when taken with Phentermine and Phentermine (Compound) resembles Tranylcypromine (Compound)
Hyoscyamine (Compound) causes Oedema (Side Effect) and Oedema (Side Effect) is caused by Phentermine (Compound) and Phentermine (Compound) resembles Tranylcypromine (Compound)
Hyoscyamine (Compound) causes Anxiety (Side Effect) and Anxiety (Side Effect) is caused by Dextroamphetamine (Compound) and Dextroamphetamine (Compound) resembles Tranylcypromine (Compound)
Hyoscyamine may cause a minor interaction that can limit clinical effects when taken with Phenelzine and Phenelzine (Compound) resembles Dextroamphetamine (Compound) and Dextroamphetamine (Compound) resembles Tranylcypromine (Compound)
Hyoscyamine may cause a minor interaction that can limit clinical effects when taken with Phenelzine and Phenelzine (Compound) resembles Phenol (Compound) and Phenol (Compound) resembles Tranylcypromine (Compound)
Hyoscyamine may cause a minor interaction that can limit clinical effects when taken with Phenelzine and Phenelzine (Compound) resembles Phenylpropanolamine (Compound) and Phenelzine may lead to a major life threatening interaction when taken with Phenylpropanolamine and Phenylpropanolamine (Compound) resembles Tranylcypromine (Compound)
Hyoscyamine may cause a minor interaction that can limit clinical effects when taken with Phenelzine and Phenelzine (Compound) binds CYP2C19 (Gene) and CYP2C19 (Gene) is bound by Tranylcypromine (Compound)
Hyoscyamine may cause a minor interaction that can limit clinical effects when taken with Phenelzine and Phenelzine (Compound) causes Oedema (Side Effect) and Oedema (Side Effect) is caused by Tranylcypromine (Compound)