DDInter1838 DDInter856
Murine IgG2a lambda monoclonal antibody against CD20 antigen (2 heavy chains of 451 residues, 2 lambda chains of 220 residues). It is produced in an antibiotic-free culture of mammalian cells. It can be covalently linked to Iodine 131 (a radioactive isotope of iodine).
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated heparin is more specific than LMWH for thrombin. Furthermore, the effects of UH can typically be reversed by using protamine sulfate.
Tositumomab {u} may cause a minor interaction that can limit clinical effects when taken with {v} Capsicum
Tositumomab {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Duloxetine
Tositumomab {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Anakinra
Tositumomab {u} may lead to a major life threatening interaction when taken with {v} Measles virus vaccine live attenuated
Tositumomab {u} may lead to a major life threatening interaction when taken with {v} Bivalirudin
Tositumomab {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} and {u} may lead to a major life threatening interaction when taken with {v} Ketorolac
Tositumomab may cause a minor interaction that can limit clinical effects when taken with Capsicum
Tositumomab may cause a moderate interaction that could exacerbate diseases when taken with Duloxetine
Tositumomab may cause a moderate interaction that could exacerbate diseases when taken with Anakinra
Tositumomab may lead to a major life threatening interaction when taken with Measles virus vaccine live attenuated
Tositumomab may lead to a major life threatening interaction when taken with Bivalirudin
Tositumomab may cause a moderate interaction that could exacerbate diseases when taken with Ketorolac and Tositumomab may lead to a major life threatening interaction when taken with Ketorolac