DDInter1845 DDInter427
A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders (From AMA Drug Evaluations Annual, 1994, p311). Tranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine with the chiral centers both located on the cylopropane ring. An irreversible monoamine oxidase inhibitor that is used as an antidepressant (INN tranylcypromine).
Cocaine can cause developmental toxicity and female reproductive toxicity according to an independent committee of scientific and health experts.
Tranylcypromine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Cocaine
Tranylcypromine {u} (Compound) causes {v} (Side Effect) Agitation
Agitation {u} (Side Effect) is caused by {v} (Compound) Cocaine
Tranylcypromine {u} (Compound) resembles {v} (Compound) Phendimetrazine
Phendimetrazine {u} may lead to a major life threatening interaction when taken with {v} Cocaine
Tranylcypromine {u} (Compound) resembles {v} (Compound) Amphetamine
Amphetamine {u} may lead to a major life threatening interaction when taken with {v} Cocaine
Tranylcypromine {u} (Compound) resembles {v} (Compound) Phenelzine
Phenelzine {u} may lead to a major life threatening interaction when taken with {v} Cocaine
Tranylcypromine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Bupivacaine
Bupivacaine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cocaine
Tranylcypromine {u} (Compound) causes {v} (Side Effect) Agitation
Agitation {u} (Side Effect) is caused by {v} (Compound) Atropine
Atropine {u} (Compound) resembles {v} (Compound) Cocaine
Tranylcypromine {u} (Compound) causes {v} (Side Effect) Tremor
Tremor {u} (Side Effect) is caused by {v} (Compound) Mepivacaine
Mepivacaine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cocaine
Tranylcypromine {u} (Compound) resembles {v} (Compound) Phendimetrazine
Phendimetrazine {u} (Compound) binds {v} (Gene) SLC6A3
SLC6A3 {u} (Gene) is bound by {v} (Compound) Cocaine
Tranylcypromine {u} (Compound) resembles {v} (Compound) Phentermine
Phentermine {u} (Compound) resembles {v} (Compound) Amphetamine
Amphetamine {u} may lead to a major life threatening interaction when taken with {v} Cocaine
Tranylcypromine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Cocaine (Compound)
Tranylcypromine (Compound) causes Agitation (Side Effect) and Agitation (Side Effect) is caused by Cocaine (Compound)
Tranylcypromine (Compound) resembles Phendimetrazine (Compound) and Phendimetrazine may lead to a major life threatening interaction when taken with Cocaine
Tranylcypromine (Compound) resembles Amphetamine (Compound) and Amphetamine may lead to a major life threatening interaction when taken with Cocaine
Tranylcypromine (Compound) resembles Phenelzine (Compound) and Phenelzine may lead to a major life threatening interaction when taken with Cocaine
Tranylcypromine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Bupivacaine (Compound) and Bupivacaine may cause a moderate interaction that could exacerbate diseases when taken with Cocaine
Tranylcypromine (Compound) causes Agitation (Side Effect) and Agitation (Side Effect) is caused by Atropine (Compound) and Atropine (Compound) resembles Cocaine (Compound)
Tranylcypromine (Compound) causes Tremor (Side Effect) and Tremor (Side Effect) is caused by Mepivacaine (Compound) and Mepivacaine may cause a moderate interaction that could exacerbate diseases when taken with Cocaine
Tranylcypromine (Compound) resembles Phendimetrazine (Compound) and Phendimetrazine (Compound) binds SLC6A3 (Gene) and SLC6A3 (Gene) is bound by Cocaine (Compound)
Tranylcypromine (Compound) resembles Phentermine (Compound) and Phentermine (Compound) resembles Amphetamine (Compound) and Amphetamine may lead to a major life threatening interaction when taken with Cocaine