DDInter1647 DDInter556
Scopolamine is a tropane alkaloid isolated from members of the _Solanaceae_ family of plants, similar to [atropine] and [hyoscyamine], all of which structurally mimic the natural neurotransmitter [acetylcholine].[A228423, A228763] Scopolamine was first synthesized in 1959, but to date, synthesis remains less efficient than extracting scopolamine from plants. As an acetylcholine analogue, scopolamine can antagonize muscarinic acetylcholine receptors (mAChRs) in the central nervous system and throughout the body, inducing several therapeutic and adverse effects related to alteration of parasympathetic nervous system and cholinergic signalling.[A228758, L31578] Due to its dose-dependent adverse effects, scopolamine was the first drug to be offered commercially as a transdermal delivery system, Scopoderm TTS®, in 1981.[A228423,
Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough. It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more effective antitussive agent to help reduce the spread of airborne infectious diseases such as tuburculosis. It was marketed in 1911.
Scopolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Galantamine
Galantamine {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Scopolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxymorphone
Oxymorphone {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Scopolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Morphine
Morphine {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Scopolamine {u} (Compound) causes {v} (Side Effect) Somnolence
Somnolence {u} (Side Effect) is caused by {v} (Compound) Dihydrocodeine
Scopolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Galantamine
Galantamine {u} (Compound) resembles {v} (Compound) Hydrocodone
Hydrocodone {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Scopolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxymorphone
Oxymorphone {u} (Compound) resembles {v} (Compound) Hydrocodone
Hydrocodone {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Scopolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Morphine
Morphine {u} (Compound) resembles {v} (Compound) Galantamine
Galantamine {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Scopolamine {u} (Compound) causes {v} (Side Effect) Somnolence
Somnolence {u} (Side Effect) is caused by {v} (Compound) Galantamine
Galantamine {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Scopolamine {u} (Compound) causes {v} (Side Effect) Pruritus
Pruritus {u} (Side Effect) is caused by {v} (Compound) Oxymorphone
Oxymorphone {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Scopolamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxymorphone
Oxymorphone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dextromethorphan
Dextromethorphan {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Scopolamine may cause a moderate interaction that could exacerbate diseases when taken with Galantamine and Galantamine (Compound) resembles Dihydrocodeine (Compound)
Scopolamine may cause a moderate interaction that could exacerbate diseases when taken with Oxymorphone and Oxymorphone (Compound) resembles Dihydrocodeine (Compound)
Scopolamine may cause a moderate interaction that could exacerbate diseases when taken with Morphine and Morphine (Compound) resembles Dihydrocodeine (Compound)
Scopolamine (Compound) causes Somnolence (Side Effect) and Somnolence (Side Effect) is caused by Dihydrocodeine (Compound)
Scopolamine may cause a moderate interaction that could exacerbate diseases when taken with Galantamine and Galantamine (Compound) resembles Hydrocodone (Compound) and Hydrocodone (Compound) resembles Dihydrocodeine (Compound)
Scopolamine may cause a moderate interaction that could exacerbate diseases when taken with Oxymorphone and Oxymorphone (Compound) resembles Hydrocodone (Compound) and Hydrocodone (Compound) resembles Dihydrocodeine (Compound)
Scopolamine may cause a moderate interaction that could exacerbate diseases when taken with Morphine and Morphine (Compound) resembles Galantamine (Compound) and Galantamine (Compound) resembles Dihydrocodeine (Compound)
Scopolamine (Compound) causes Somnolence (Side Effect) and Somnolence (Side Effect) is caused by Galantamine (Compound) and Galantamine (Compound) resembles Dihydrocodeine (Compound)
Scopolamine (Compound) causes Pruritus (Side Effect) and Pruritus (Side Effect) is caused by Oxymorphone (Compound) and Oxymorphone (Compound) resembles Dihydrocodeine (Compound)
Scopolamine may cause a moderate interaction that could exacerbate diseases when taken with Oxymorphone and Oxymorphone may cause a moderate interaction that could exacerbate diseases when taken with Dextromethorphan and Dextromethorphan (Compound) resembles Dihydrocodeine (Compound)