DDInter1440 DDInter1376
Phenelzine, with the formula β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant that is effective in the treatment of panic disorder and social anxiety disorder. It was developed by Parke Davis and originally FDA approved on June 9th, 1961. It is currently approved under prescription by the name of Nardil.
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26, 2020.[L12573,L12582] The US approval was followed by the approval in Canada on October 2, 2020. In November 2021, ozanimod was also approved by the European Commission for the treatment of adults with relapsing remitting multiple sclerosis.[L39377,L39382] MS is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Inflammatory bowel disease also a chronic inflammatory condition and can cause persistent abdominal pain, diarrhea, bloody stools, and vomiting. In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard in MS therapy. Studies involving patients with inflammatory bowel disease have also shown promising results.[A189318,A189342]
Phenelzine {u} (Compound) resembles {v} (Compound) Selegiline
Phenelzine {u} may lead to a major life threatening interaction when taken with {v} Phentermine
Phenelzine {u} (Compound) resembles {v} (Compound) Fenproporex
Phenelzine {u} (Compound) binds {v} (Gene) AOC3
Phenelzine {u} (Compound) upregulates {v} (Gene) DENND2D
Phenelzine {u} (Compound) downregulates {v} (Gene) NPC1
Phenelzine {u} (Compound) causes {v} (Side Effect) Lupus-like syndrome
Phenelzine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Scopolamine
Phenelzine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Glycopyrronium
Phenelzine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Repaglinide
Phenelzine (Compound) resembles Selegiline (Compound)
Phenelzine may lead to a major life threatening interaction when taken with Phentermine
Phenelzine (Compound) resembles Fenproporex (Compound)
Phenelzine (Compound) binds AOC3 (Gene)
Phenelzine (Compound) upregulates DENND2D (Gene)
Phenelzine (Compound) downregulates NPC1 (Gene)
Phenelzine (Compound) causes Lupus-like syndrome (Side Effect)
Phenelzine may cause a minor interaction that can limit clinical effects when taken with Scopolamine
Phenelzine may cause a minor interaction that can limit clinical effects when taken with Glycopyrronium
Phenelzine may cause a moderate interaction that could exacerbate diseases when taken with Repaglinide