DDInter1244 DDInter781
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine], and [oxycodone]. Morphine was granted FDA approval in 1941.
Fosinopril is a phosphinic acid-containing ester prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly hydrolyzed to fosinoprilat, its principle active metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Fosinopril may be used to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and microalbuminuria or overt nephropathy.
Morphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Enalapril
Enalapril {u} (Compound) resembles {v} (Compound) Fosinopril
Morphine {u} (Compound) causes {v} (Side Effect) Urticaria
Urticaria {u} (Side Effect) is caused by {v} (Compound) Fosinopril
Morphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Enalapril
Enalapril {u} (Compound) resembles {v} (Compound) Spirapril
Spirapril {u} (Compound) resembles {v} (Compound) Fosinopril
Morphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Trandolapril
Trandolapril {u} (Compound) resembles {v} (Compound) Enalapril
Enalapril {u} (Compound) resembles {v} (Compound) Fosinopril
Morphine {u} (Compound) causes {v} (Side Effect) Urticaria
Urticaria {u} (Side Effect) is caused by {v} (Compound) Enalapril
Enalapril {u} (Compound) resembles {v} (Compound) Fosinopril
Morphine {u} (Compound) causes {v} (Side Effect) Chills
Chills {u} (Side Effect) is caused by {v} (Compound) Cilazapril
Cilazapril {u} (Compound) resembles {v} (Compound) Fosinopril
Morphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Quinapril
Quinapril {u} (Compound) resembles {v} (Compound) Enalapril
Enalapril {u} (Compound) resembles {v} (Compound) Fosinopril
Morphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Quinapril
Quinapril {u} (Compound) resembles {v} (Compound) Spirapril
Spirapril {u} (Compound) resembles {v} (Compound) Fosinopril
Morphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Captopril
Captopril {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Fosinopril
Morphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Captopril
Captopril {u} (Compound) binds {v} (Gene) SLC15A1
SLC15A1 {u} (Gene) is bound by {v} (Compound) Fosinopril
Morphine may cause a moderate interaction that could exacerbate diseases when taken with Enalapril and Enalapril (Compound) resembles Fosinopril (Compound)
Morphine (Compound) causes Urticaria (Side Effect) and Urticaria (Side Effect) is caused by Fosinopril (Compound)
Morphine may cause a moderate interaction that could exacerbate diseases when taken with Enalapril and Enalapril (Compound) resembles Spirapril (Compound) and Spirapril (Compound) resembles Fosinopril (Compound)
Morphine may cause a moderate interaction that could exacerbate diseases when taken with Trandolapril and Trandolapril (Compound) resembles Enalapril (Compound) and Enalapril (Compound) resembles Fosinopril (Compound)
Morphine (Compound) causes Urticaria (Side Effect) and Urticaria (Side Effect) is caused by Enalapril (Compound) and Enalapril (Compound) resembles Fosinopril (Compound)
Morphine (Compound) causes Chills (Side Effect) and Chills (Side Effect) is caused by Cilazapril (Compound) and Cilazapril (Compound) resembles Fosinopril (Compound)
Morphine may cause a moderate interaction that could exacerbate diseases when taken with Quinapril and Quinapril (Compound) resembles Enalapril (Compound) and Enalapril (Compound) resembles Fosinopril (Compound)
Morphine may cause a moderate interaction that could exacerbate diseases when taken with Quinapril and Quinapril (Compound) resembles Spirapril (Compound) and Spirapril (Compound) resembles Fosinopril (Compound)
Morphine may cause a moderate interaction that could exacerbate diseases when taken with Captopril and Captopril (Compound) treats hypertension (Disease) and hypertension (Disease) is treated by Fosinopril (Compound)
Morphine may cause a moderate interaction that could exacerbate diseases when taken with Captopril and Captopril (Compound) binds SLC15A1 (Gene) and SLC15A1 (Gene) is bound by Fosinopril (Compound)