DDInter1396 DDInter954
An oligosaccharide antibiotic produced by various streptomyces. [PubChem]
Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy. Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its mode of beta decay. As a result of beta decay, approximately 10% of its energy and radiation dose is via gamma radiation, while the other 90% (beta radiation) causes tissue damage without contributing to any ability to see or image the isotope. Low levels of beta radiation are also known for causing cancer as this dose is highly mutagenic. For this reason, less toxic iodine isotopes such as I-123 are more frequently used in nuclear imaging, while I-131 is reserved for its tissue destroying effects. Because the thyroid gland naturally takes up iodine from the body, therapeutic methods using radioisotopes can take advantage of this mechanism for localization of drug to the site of malignancy. Therapeutic solutions of Sodium Iodide-131 are indicated for the treatment of hyperthyroidism and thyroid carcinomas that take up iodine. Palliative effects may be observed in patients with advanced thyroid malignancy if the metastatic lesions take up iodine. It is also indicated for use in performance of the radioactive iodide (RAI) uptake test to evaluate thyroid function.
Paromomycin {u} (Compound) resembles {v} (Compound) Lactulose
Lactulose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Primaquine
Primaquine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iodide I-131
Paromomycin {u} (Compound) resembles {v} (Compound) Kanamycin
Kanamycin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ticarcillin
Ticarcillin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iodide I-131
Paromomycin {u} (Compound) resembles {v} (Compound) Kanamycin
Kanamycin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenyl salicylate
Phenyl salicylate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iodide I-131
Paromomycin {u} (Compound) resembles {v} (Compound) Acarbose
Acarbose {u} may cause a minor interaction that can limit clinical effects when taken with {v} Anisindione
Anisindione {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iodide I-131
Paromomycin {u} (Compound) resembles {v} (Compound) Neomycin
Neomycin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Warfarin
Warfarin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iodide I-131
Paromomycin {u} (Compound) resembles {v} (Compound) Kanamycin
Kanamycin {u} may lead to a major life threatening interaction when taken with {v} Iothalamic acid
Iothalamic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iodide I-131
Paromomycin {u} (Compound) upregulates {v} (Gene) WRB
WRB {u} (Gene) is upregulated by {v} (Compound) Propylthiouracil
Propylthiouracil {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iodide I-131
Paromomycin {u} (Compound) resembles {v} (Compound) Neomycin
Neomycin {u} may lead to a major life threatening interaction when taken with {v} Iothalamic acid
Iothalamic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iodide I-131
Paromomycin {u} (Compound) resembles {v} (Compound) Kanamycin
Kanamycin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mezlocillin
Mezlocillin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iodide I-131
Paromomycin {u} (Compound) resembles {v} (Compound) Lactulose
Lactulose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Deflazacort
Deflazacort {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iodide I-131
Paromomycin (Compound) resembles Lactulose (Compound) and Lactulose may cause a moderate interaction that could exacerbate diseases when taken with Primaquine and Primaquine may cause a moderate interaction that could exacerbate diseases when taken with Iodide I-131
Paromomycin (Compound) resembles Kanamycin (Compound) and Kanamycin may cause a moderate interaction that could exacerbate diseases when taken with Ticarcillin and Ticarcillin may cause a moderate interaction that could exacerbate diseases when taken with Iodide I-131
Paromomycin (Compound) resembles Kanamycin (Compound) and Kanamycin may cause a moderate interaction that could exacerbate diseases when taken with Phenyl salicylate and Phenyl salicylate may cause a moderate interaction that could exacerbate diseases when taken with Iodide I-131
Paromomycin (Compound) resembles Acarbose (Compound) and Acarbose may cause a minor interaction that can limit clinical effects when taken with Anisindione and Anisindione may cause a moderate interaction that could exacerbate diseases when taken with Iodide I-131
Paromomycin (Compound) resembles Neomycin (Compound) and Neomycin may cause a moderate interaction that could exacerbate diseases when taken with Warfarin and Warfarin may cause a moderate interaction that could exacerbate diseases when taken with Iodide I-131
Paromomycin (Compound) resembles Kanamycin (Compound) and Kanamycin may lead to a major life threatening interaction when taken with Iothalamic acid and Iothalamic acid may cause a moderate interaction that could exacerbate diseases when taken with Iodide I-131
Paromomycin (Compound) upregulates WRB (Gene) and WRB (Gene) is upregulated by Propylthiouracil (Compound) and Propylthiouracil may cause a moderate interaction that could exacerbate diseases when taken with Iodide I-131
Paromomycin (Compound) resembles Neomycin (Compound) and Neomycin may lead to a major life threatening interaction when taken with Iothalamic acid and Iothalamic acid may cause a moderate interaction that could exacerbate diseases when taken with Iodide I-131
Paromomycin (Compound) resembles Kanamycin (Compound) and Kanamycin may cause a moderate interaction that could exacerbate diseases when taken with Mezlocillin and Mezlocillin may cause a moderate interaction that could exacerbate diseases when taken with Iodide I-131
Paromomycin (Compound) resembles Lactulose (Compound) and Lactulose may cause a moderate interaction that could exacerbate diseases when taken with Deflazacort and Deflazacort may cause a moderate interaction that could exacerbate diseases when taken with Iodide I-131