DDInter1474 DDInter856
Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated heparin is more specific than LMWH for thrombin. Furthermore, the effects of UH can typically be reversed by using protamine sulfate.
Piperacillin {u} (Compound) resembles {v} (Compound) Meticillin
Piperacillin {u} (Compound) resembles {v} (Compound) Flucloxacillin
Piperacillin {u} (Compound) binds {v} (Gene) SLC22A6
Piperacillin {u} (Compound) upregulates {v} (Gene) TBP
Piperacillin {u} (Compound) downregulates {v} (Gene) RFC2
Piperacillin {u} (Compound) causes {v} (Side Effect) Eczema
Piperacillin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Clarithromycin
Piperacillin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Gentamicin
Piperacillin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Doxycycline
Piperacillin {u} may lead to a major life threatening interaction when taken with {v} Vancomycin
Piperacillin (Compound) resembles Meticillin (Compound)
Piperacillin (Compound) resembles Flucloxacillin (Compound)
Piperacillin (Compound) binds SLC22A6 (Gene)
Piperacillin (Compound) upregulates TBP (Gene)
Piperacillin (Compound) downregulates RFC2 (Gene)
Piperacillin (Compound) causes Eczema (Side Effect)
Piperacillin may cause a minor interaction that can limit clinical effects when taken with Clarithromycin
Piperacillin may cause a moderate interaction that could exacerbate diseases when taken with Gentamicin
Piperacillin may cause a moderate interaction that could exacerbate diseases when taken with Doxycycline
Piperacillin may lead to a major life threatening interaction when taken with Vancomycin