DDInter79 DDInter278
Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called _dihydropyridine calcium channel blockers_. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities than other calcium channel blockers. Amlodipine is commonly used in the treatment of high blood pressure and angina. Amlodipine has antioxidant properties and an ability to enhance the production of nitric oxide (NO), an important vasodilator that decreases blood pressure. The option for single daily dosing of amlodipine is an attractive feature of this drug [FDA label].
Calcium lactate is a salt that consists of two lactate anions for each calcium cation (Ca2+). It is prepared commercially by the neutralization of lactic acid with calcium carbonate or calcium hydroxide. Approved by the FDA as a direct food substance affirmed as generally recognized as safe, calcium lactate is used as a firming agent, flavoring agent, leavening agent, stabilizer, and thickener . Calcium lactate is also found in daily dietary supplements as a source of calcium. It is also available in various hydrate forms, where calcium lactate pentahydrate is the most common.
Amlodipine {u} (Compound) resembles {v} (Compound) Nilvadipine
Amlodipine {u} (Compound) resembles {v} (Compound) Isradipine
Amlodipine {u} (Compound) treats {v} (Disease) hypertension
Amlodipine {u} (Compound) binds {v} (Gene) CACNA1B
Amlodipine {u} (Compound) upregulates {v} (Gene) ACLY
Amlodipine {u} (Compound) palliates {v} (Disease) coronary artery disease
Amlodipine {u} (Compound) is included by {v} (Pharmacologic Class) Dihydropyridines
Amlodipine {u} (Compound) downregulates {v} (Gene) NOLC1
Amlodipine {u} (Compound) causes {v} (Side Effect) Weight increased
Amlodipine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Darolutamide
Amlodipine (Compound) resembles Nilvadipine (Compound)
Amlodipine (Compound) resembles Isradipine (Compound)
Amlodipine (Compound) treats hypertension (Disease)
Amlodipine (Compound) binds CACNA1B (Gene)
Amlodipine (Compound) upregulates ACLY (Gene)
Amlodipine (Compound) palliates coronary artery disease (Disease)
Amlodipine (Compound) is included by Dihydropyridines (Pharmacologic Class)
Amlodipine (Compound) downregulates NOLC1 (Gene)
Amlodipine (Compound) causes Weight increased (Side Effect)
Amlodipine may cause a minor interaction that can limit clinical effects when taken with Darolutamide