DDInter1139 DDInter704
A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and not on the mTORC2 protein.
Mefenamic acid {u} (Compound) downregulates {v} (Gene) ZNF586
ZNF586 {u} (Gene) is downregulated by {v} (Compound) Everolimus
Mefenamic acid {u} (Compound) upregulates {v} (Gene) SUV39H1
SUV39H1 {u} (Gene) is downregulated by {v} (Compound) Everolimus
Mefenamic acid {u} (Compound) causes {v} (Side Effect) Gastritis
Gastritis {u} (Side Effect) is caused by {v} (Compound) Everolimus
Mefenamic acid {u} (Compound) downregulates {v} (Gene) ZNF586
ZNF586 {u} (Gene) is upregulated by {v} (Compound) Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Everolimus
Mefenamic acid {u} (Compound) upregulates {v} (Gene) SUV39H1
SUV39H1 {u} (Gene) is downregulated by {v} (Compound) Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Everolimus
Mefenamic acid {u} (Compound) causes {v} (Side Effect) Gastritis
Gastritis {u} (Side Effect) is caused by {v} (Compound) Temsirolimus
Temsirolimus {u} (Compound) resembles {v} (Compound) Everolimus
Mefenamic acid {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Pimecrolimus
Pimecrolimus {u} (Compound) resembles {v} (Compound) Everolimus
Mefenamic acid {u} (Compound) resembles {v} (Compound) Ketoprofen
Ketoprofen {u} (Compound) upregulates {v} (Gene) HMOX1
HMOX1 {u} (Gene) is upregulated by {v} (Compound) Everolimus
Mefenamic acid {u} (Compound) downregulates {v} (Gene) ZNF586
ZNF586 {u} (Gene) is regulated by {v} (Gene) SIRT1
SIRT1 {u} (Gene) is upregulated by {v} (Compound) Everolimus
Mefenamic acid {u} (Compound) upregulates {v} (Gene) SUV39H1
SUV39H1 {u} (Gene) interacts with {v} (Gene) HIST1H3H
HIST1H3H {u} (Gene) is upregulated by {v} (Compound) Everolimus
Mefenamic acid (Compound) downregulates ZNF586 (Gene) and ZNF586 (Gene) is downregulated by Everolimus (Compound)
Mefenamic acid (Compound) upregulates SUV39H1 (Gene) and SUV39H1 (Gene) is downregulated by Everolimus (Compound)
Mefenamic acid (Compound) causes Gastritis (Side Effect) and Gastritis (Side Effect) is caused by Everolimus (Compound)
Mefenamic acid (Compound) downregulates ZNF586 (Gene) and ZNF586 (Gene) is upregulated by Sirolimus (Compound) and Sirolimus (Compound) resembles Everolimus (Compound)
Mefenamic acid (Compound) upregulates SUV39H1 (Gene) and SUV39H1 (Gene) is downregulated by Sirolimus (Compound) and Sirolimus (Compound) resembles Everolimus (Compound)
Mefenamic acid (Compound) causes Gastritis (Side Effect) and Gastritis (Side Effect) is caused by Temsirolimus (Compound) and Temsirolimus (Compound) resembles Everolimus (Compound)
Mefenamic acid (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Pimecrolimus (Compound) and Pimecrolimus (Compound) resembles Everolimus (Compound)
Mefenamic acid (Compound) resembles Ketoprofen (Compound) and Ketoprofen (Compound) upregulates HMOX1 (Gene) and HMOX1 (Gene) is upregulated by Everolimus (Compound)
Mefenamic acid (Compound) downregulates ZNF586 (Gene) and ZNF586 (Gene) is regulated by SIRT1 (Gene) and SIRT1 (Gene) is upregulated by Everolimus (Compound)
Mefenamic acid (Compound) upregulates SUV39H1 (Gene) and SUV39H1 (Gene) interacts with HIST1H3H (Gene) and HIST1H3H (Gene) is upregulated by Everolimus (Compound)