DDInter513 DDInter1473
Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like [hydrocortisone] and [prednisolone]. Dexamethasone was granted FDA approval on 30 October 1958. In a press release for the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial on 16 June 2020, dexamethasone was recommended for use in COVID-19 patients with severe respiratory symptoms. Dexamethasone reduced deaths by approximately one third in patients requiring ventilation and by one fifth in those requiring oxygen.
Pipecuronium is a piperazinyl androstane derivative which is a non-depolarizing neuromuscular blocking agent.
Dexamethasone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Dexamethasone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Rocuronium
Rocuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Dexamethasone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Rocuronium
Rocuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Dexamethasone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Rocuronium
Rocuronium {u} (Compound) resembles {v} (Compound) Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Dexamethasone {u} (Compound) upregulates {v} (Gene) WRB
WRB {u} (Gene) is upregulated by {v} (Compound) Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Dexamethasone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Vecuronium
Vecuronium {u} (Compound) resembles {v} (Compound) Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Dexamethasone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Vecuronium
Vecuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Dexamethasone {u} (Compound) downregulates {v} (Gene) GDF15
GDF15 {u} (Gene) is downregulated by {v} (Compound) Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Dexamethasone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pancuronium
Pancuronium {u} (Compound) binds {v} (Gene) CHRNB1
CHRNB1 {u} (Gene) is bound by {v} (Compound) Pipecuronium
Dexamethasone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Rocuronium
Rocuronium {u} (Compound) binds {v} (Gene) CHRNB1
CHRNB1 {u} (Gene) is bound by {v} (Compound) Pipecuronium
Dexamethasone may cause a moderate interaction that could exacerbate diseases when taken with Pancuronium and Pancuronium (Compound) resembles Pipecuronium (Compound)
Dexamethasone may cause a moderate interaction that could exacerbate diseases when taken with Rocuronium and Rocuronium (Compound) resembles Pipecuronium (Compound)
Dexamethasone may cause a moderate interaction that could exacerbate diseases when taken with Pancuronium and Pancuronium (Compound) resembles Rocuronium (Compound) and Rocuronium (Compound) resembles Pipecuronium (Compound)
Dexamethasone may cause a moderate interaction that could exacerbate diseases when taken with Rocuronium and Rocuronium (Compound) resembles Pancuronium (Compound) and Pancuronium (Compound) resembles Pipecuronium (Compound)
Dexamethasone (Compound) upregulates WRB (Gene) and WRB (Gene) is upregulated by Pancuronium (Compound) and Pancuronium (Compound) resembles Pipecuronium (Compound)
Dexamethasone may cause a moderate interaction that could exacerbate diseases when taken with Vecuronium and Vecuronium (Compound) resembles Pancuronium (Compound) and Pancuronium (Compound) resembles Pipecuronium (Compound)
Dexamethasone may cause a moderate interaction that could exacerbate diseases when taken with Pancuronium and Pancuronium (Compound) resembles Vecuronium (Compound) and Vecuronium (Compound) resembles Pipecuronium (Compound)
Dexamethasone (Compound) downregulates GDF15 (Gene) and GDF15 (Gene) is downregulated by Pancuronium (Compound) and Pancuronium (Compound) resembles Pipecuronium (Compound)
Dexamethasone may cause a moderate interaction that could exacerbate diseases when taken with Pancuronium and Pancuronium (Compound) binds CHRNB1 (Gene) and CHRNB1 (Gene) is bound by Pipecuronium (Compound)
Dexamethasone may cause a moderate interaction that could exacerbate diseases when taken with Rocuronium and Rocuronium (Compound) binds CHRNB1 (Gene) and CHRNB1 (Gene) is bound by Pipecuronium (Compound)