DDInter1867 DDInter650
A phenothiazine used as an antipsychotic agent and as an antiemetic.
Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with [pseudoephedrine]. Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons, inhibiting norepinephrine reuptake and displacing more norepinephrine from storage vesicles.[A193650,L12972] Ephedrine is used for its vasoconstrictive, positive chronotropic, and positive inotropic effects. Ephedrine and [phenylephrine] are still used to treat hypotension, but their use in other indications has decreased due to the development of more selective adrenergic agonists.[A193701,A193704,L12975] Ephedrine was granted a type 7 FDA Approval on 29 April 2016.
Triflupromazine {u} (Compound) binds {v} (Gene) BCHE
BCHE {u} (Gene) is bound by {v} (Compound) Ephedrine
Triflupromazine {u} (Compound) resembles {v} (Compound) Promazine
Promazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ephedrine
Triflupromazine {u} (Compound) resembles {v} (Compound) Methotrimeprazine
Methotrimeprazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ephedrine
Triflupromazine {u} (Compound) resembles {v} (Compound) Clomipramine
Clomipramine {u} may lead to a major life threatening interaction when taken with {v} Ephedrine
Triflupromazine {u} (Compound) binds {v} (Gene) BCHE
BCHE {u} (Gene) is bound by {v} (Compound) Chlorpromazine
Chlorpromazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ephedrine
Triflupromazine {u} (Compound) resembles {v} (Compound) Promazine
Promazine {u} (Compound) binds {v} (Gene) ADRA1A
ADRA1A {u} (Gene) is bound by {v} (Compound) Ephedrine
Triflupromazine {u} (Compound) resembles {v} (Compound) Methdilazine
Methdilazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amphetamine
Amphetamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ephedrine
Triflupromazine {u} (Compound) resembles {v} (Compound) Perphenazine
Perphenazine {u} (Compound) causes {v} (Side Effect) Psychotic disorder
Psychotic disorder {u} (Side Effect) is caused by {v} (Compound) Ephedrine
Triflupromazine {u} (Compound) resembles {v} (Compound) Thioridazine
Thioridazine {u} (Compound) upregulates {v} (Gene) ADRB2
ADRB2 {u} (Gene) is bound by {v} (Compound) Ephedrine
Triflupromazine {u} (Compound) resembles {v} (Compound) Pipotiazine
Pipotiazine {u} (Compound) resembles {v} (Compound) Methotrimeprazine
Methotrimeprazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ephedrine
Triflupromazine (Compound) binds BCHE (Gene) and BCHE (Gene) is bound by Ephedrine (Compound)
Triflupromazine (Compound) resembles Promazine (Compound) and Promazine may cause a moderate interaction that could exacerbate diseases when taken with Ephedrine
Triflupromazine (Compound) resembles Methotrimeprazine (Compound) and Methotrimeprazine may cause a moderate interaction that could exacerbate diseases when taken with Ephedrine
Triflupromazine (Compound) resembles Clomipramine (Compound) and Clomipramine may lead to a major life threatening interaction when taken with Ephedrine
Triflupromazine (Compound) binds BCHE (Gene) and BCHE (Gene) is bound by Chlorpromazine (Compound) and Chlorpromazine may cause a moderate interaction that could exacerbate diseases when taken with Ephedrine
Triflupromazine (Compound) resembles Promazine (Compound) and Promazine (Compound) binds ADRA1A (Gene) and ADRA1A (Gene) is bound by Ephedrine (Compound)
Triflupromazine (Compound) resembles Methdilazine (Compound) and Methdilazine may cause a moderate interaction that could exacerbate diseases when taken with Amphetamine and Amphetamine may cause a moderate interaction that could exacerbate diseases when taken with Ephedrine
Triflupromazine (Compound) resembles Perphenazine (Compound) and Perphenazine (Compound) causes Psychotic disorder (Side Effect) and Psychotic disorder (Side Effect) is caused by Ephedrine (Compound)
Triflupromazine (Compound) resembles Thioridazine (Compound) and Thioridazine (Compound) upregulates ADRB2 (Gene) and ADRB2 (Gene) is bound by Ephedrine (Compound)
Triflupromazine (Compound) resembles Pipotiazine (Compound) and Pipotiazine (Compound) resembles Methotrimeprazine (Compound) and Methotrimeprazine may cause a moderate interaction that could exacerbate diseases when taken with Ephedrine