DDInter948 DDInter544
Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
A dideoxynucleoside compound in which the 3&#39;-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative active metabolite.
Didanosine {u} (Compound) resembles {v} (Compound) Entecavir
Didanosine {u} (Compound) resembles {v} (Compound) Zalcitabine
Didanosine {u} (Compound) treats {v} (Disease) acquired immunodeficiency syndrome
Didanosine {u} (Compound) binds {v} (Gene) PNP
Didanosine {u} (Compound) upregulates {v} (Gene) NOTCH1
Didanosine {u} (Compound) is included by {v} (Pharmacologic Class) Nucleoside Reverse Transcriptase Inhibitors
Didanosine {u} (Compound) downregulates {v} (Gene) HMG20B
Didanosine {u} (Compound) causes {v} (Side Effect) Leukoderma
Didanosine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Tetracycline
Didanosine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Minocycline
Didanosine (Compound) resembles Entecavir (Compound)
Didanosine (Compound) resembles Zalcitabine (Compound)
Didanosine (Compound) treats acquired immunodeficiency syndrome (Disease)
Didanosine (Compound) binds PNP (Gene)
Didanosine (Compound) upregulates NOTCH1 (Gene)
Didanosine (Compound) is included by Nucleoside Reverse Transcriptase Inhibitors (Pharmacologic Class)
Didanosine (Compound) downregulates HMG20B (Gene)
Didanosine (Compound) causes Leukoderma (Side Effect)
Didanosine may cause a minor interaction that can limit clinical effects when taken with Tetracycline
Didanosine may cause a minor interaction that can limit clinical effects when taken with Minocycline