DDInter504 DDInter23
Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipramine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. Secondary amine TCAs, such as desipramine and nortriptyline, are more potent inhibitors of norepinephrine reuptake than tertiary amine TCAs, such as amitriptyline and doxepine. TCAs also down-regulate cerebral cortical &beta;-adrenergic receptors and sensitize post-synaptic serotonergic receptors with chronic use
Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever. As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby preventing the symptoms associated with histamine release such as pruritis, vasodilation, hypotension, edema, bronchoconstriction, and tachycardia. Acrivastine is currently available in combination with pseudoephedrine as the FDA-approved product Semprex-D.
Desipramine {u} (Compound) resembles {v} (Compound) Maprotiline
Maprotiline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acrivastine
Desipramine {u} (Compound) resembles {v} (Compound) Protriptyline
Protriptyline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acrivastine
Desipramine {u} (Compound) resembles {v} (Compound) Maprotiline
Maprotiline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Atropine
Atropine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acrivastine
Desipramine {u} (Compound) resembles {v} (Compound) Doxepin
Doxepin {u} may lead to a major life threatening interaction when taken with {v} Cyclobenzaprine
Cyclobenzaprine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acrivastine
Desipramine {u} (Compound) resembles {v} (Compound) Methdilazine
Methdilazine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Hyaluronidase
Hyaluronidase {u} may cause a minor interaction that can limit clinical effects when taken with {v} Acrivastine
Desipramine {u} (Compound) resembles {v} (Compound) Chlorpromazine
Chlorpromazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Atropine
Atropine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acrivastine
Desipramine {u} (Compound) resembles {v} (Compound) Promazine
Promazine {u} (Compound) resembles {v} (Compound) Cyclobenzaprine
Cyclobenzaprine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acrivastine
Desipramine {u} (Compound) resembles {v} (Compound) Protriptyline
Protriptyline {u} (Compound) resembles {v} (Compound) Cyclobenzaprine
Cyclobenzaprine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acrivastine
Desipramine {u} (Compound) resembles {v} (Compound) Protriptyline
Protriptyline {u} (Compound) resembles {v} (Compound) Maprotiline
Maprotiline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acrivastine
Desipramine {u} (Compound) resembles {v} (Compound) Clomipramine
Clomipramine {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Doxepin
Doxepin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acrivastine
Desipramine (Compound) resembles Maprotiline (Compound) and Maprotiline may cause a moderate interaction that could exacerbate diseases when taken with Acrivastine
Desipramine (Compound) resembles Protriptyline (Compound) and Protriptyline may cause a moderate interaction that could exacerbate diseases when taken with Acrivastine
Desipramine (Compound) resembles Maprotiline (Compound) and Maprotiline may cause a moderate interaction that could exacerbate diseases when taken with Atropine and Atropine may cause a moderate interaction that could exacerbate diseases when taken with Acrivastine
Desipramine (Compound) resembles Doxepin (Compound) and Doxepin may lead to a major life threatening interaction when taken with Cyclobenzaprine and Cyclobenzaprine may cause a moderate interaction that could exacerbate diseases when taken with Acrivastine
Desipramine (Compound) resembles Methdilazine (Compound) and Methdilazine may cause a minor interaction that can limit clinical effects when taken with Hyaluronidase and Hyaluronidase may cause a minor interaction that can limit clinical effects when taken with Acrivastine
Desipramine (Compound) resembles Chlorpromazine (Compound) and Chlorpromazine may cause a moderate interaction that could exacerbate diseases when taken with Atropine and Atropine may cause a moderate interaction that could exacerbate diseases when taken with Acrivastine
Desipramine (Compound) resembles Promazine (Compound) and Promazine (Compound) resembles Cyclobenzaprine (Compound) and Cyclobenzaprine may cause a moderate interaction that could exacerbate diseases when taken with Acrivastine
Desipramine (Compound) resembles Protriptyline (Compound) and Protriptyline (Compound) resembles Cyclobenzaprine (Compound) and Cyclobenzaprine may cause a moderate interaction that could exacerbate diseases when taken with Acrivastine
Desipramine (Compound) resembles Protriptyline (Compound) and Protriptyline (Compound) resembles Maprotiline (Compound) and Maprotiline may cause a moderate interaction that could exacerbate diseases when taken with Acrivastine
Desipramine (Compound) resembles Clomipramine (Compound) and Clomipramine (Compound) resembles Doxepin (Compound) and Clomipramine may cause a moderate interaction that could exacerbate diseases when taken with Doxepin and Doxepin may cause a moderate interaction that could exacerbate diseases when taken with Acrivastine