DDInter1822 DDInter960
Aminoglycosides, many of which are derived directly from _Streptomyces_ spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic _Pseudomonas aeruginosa_ infections in cystic fibrosis patients, as _P. aeruginosa_ is notoriously inherently resistant to many antibiotics.[A232294, A232299, L32739] However, tobramycin can also be administered intravenously and topically to treat a variety of infections caused by susceptible bacteria.[L32744, L32749] Its use is limited in some cases by characteristic toxicities such as nephrotoxicity and ototoxicity, yet it remains a valuable option in the face of growing resistance to front-line antibiotics such as β-lactams and cephalosporins.[A232294, A232349, L
Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Tobramycin {u} (Compound) causes {v} (Side Effect) Injection site pain
Injection site pain {u} (Side Effect) is caused by {v} (Compound) Iohexol
Tobramycin {u} (Compound) resembles {v} (Compound) Neomycin
Neomycin {u} may lead to a major life threatening interaction when taken with {v} Iohexol
Tobramycin {u} (Compound) causes {v} (Side Effect) Injection site pain
Injection site pain {u} (Side Effect) is caused by {v} (Compound) Iodixanol
Iodixanol {u} (Compound) resembles {v} (Compound) Iohexol
Tobramycin {u} (Compound) causes {v} (Side Effect) Hypersensitivity
Hypersensitivity {u} (Side Effect) is caused by {v} (Compound) Labetalol
Labetalol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iohexol
Tobramycin {u} (Compound) resembles {v} (Compound) Neomycin
Neomycin {u} may lead to a major life threatening interaction when taken with {v} Iodixanol
Iodixanol {u} (Compound) resembles {v} (Compound) Iohexol
Tobramycin {u} (Compound) resembles {v} (Compound) Paromomycin
Paromomycin {u} (Compound) resembles {v} (Compound) Kanamycin
Kanamycin {u} may lead to a major life threatening interaction when taken with {v} Iohexol
Tobramycin {u} (Compound) resembles {v} (Compound) Neomycin
Neomycin {u} (Compound) causes {v} (Side Effect) Hypersensitivity
Hypersensitivity {u} (Side Effect) is caused by {v} (Compound) Iohexol
Tobramycin {u} (Compound) resembles {v} (Compound) Amikacin
Amikacin {u} (Compound) resembles {v} (Compound) Neomycin
Neomycin {u} may lead to a major life threatening interaction when taken with {v} Iohexol
Tobramycin {u} (Compound) causes {v} (Side Effect) Injection site pain
Injection site pain {u} (Side Effect) is caused by {v} (Compound) Ketorolac
Ketorolac {u} may lead to a major life threatening interaction when taken with {v} Iohexol
Tobramycin {u} (Compound) causes {v} (Side Effect) Bone disorder
Bone disorder {u} (Side Effect) is caused by {v} (Compound) Dexmethylphenidate
Dexmethylphenidate {u} may lead to a major life threatening interaction when taken with {v} Iohexol
Tobramycin (Compound) causes Injection site pain (Side Effect) and Injection site pain (Side Effect) is caused by Iohexol (Compound)
Tobramycin (Compound) resembles Neomycin (Compound) and Neomycin may lead to a major life threatening interaction when taken with Iohexol
Tobramycin (Compound) causes Injection site pain (Side Effect) and Injection site pain (Side Effect) is caused by Iodixanol (Compound) and Iodixanol (Compound) resembles Iohexol (Compound)
Tobramycin (Compound) causes Hypersensitivity (Side Effect) and Hypersensitivity (Side Effect) is caused by Labetalol (Compound) and Labetalol may cause a moderate interaction that could exacerbate diseases when taken with Iohexol
Tobramycin (Compound) resembles Neomycin (Compound) and Neomycin may lead to a major life threatening interaction when taken with Iodixanol and Iodixanol (Compound) resembles Iohexol (Compound)
Tobramycin (Compound) resembles Paromomycin (Compound) and Paromomycin (Compound) resembles Kanamycin (Compound) and Kanamycin may lead to a major life threatening interaction when taken with Iohexol
Tobramycin (Compound) resembles Neomycin (Compound) and Neomycin (Compound) causes Hypersensitivity (Side Effect) and Hypersensitivity (Side Effect) is caused by Iohexol (Compound)
Tobramycin (Compound) resembles Amikacin (Compound) and Amikacin (Compound) resembles Neomycin (Compound) and Neomycin may lead to a major life threatening interaction when taken with Iohexol
Tobramycin (Compound) causes Injection site pain (Side Effect) and Injection site pain (Side Effect) is caused by Ketorolac (Compound) and Ketorolac may lead to a major life threatening interaction when taken with Iohexol
Tobramycin (Compound) causes Bone disorder (Side Effect) and Bone disorder (Side Effect) is caused by Dexmethylphenidate (Compound) and Dexmethylphenidate may lead to a major life threatening interaction when taken with Iohexol