DDInter853 DDInter1180
Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2), particularly within the mesolimbic and mesocortical systems of the brain. Haloperidol is indicated for the treatment of the manifestations of several psychotic disorders including schizophrenia, acute psychosis, Tourette syndrome, and other severe behavioural states. It is also used off-label for the management of chorea associated with Huntington's disease and for the treatment of intractable hiccups as it is a potent antiemetic. Dopamine-antagonizing medications such as haloperidol are though to improve psychotic symptoms and states that are caused by an over-production of dopamine, such as schizophrenia, which is
Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Haloperidol {u} (Compound) resembles {v} (Compound) Bepotastine
Haloperidol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Loperamide
Haloperidol {u} (Compound) resembles {v} (Compound) Sertindole
Haloperidol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cetirizine
Haloperidol {u} (Compound) binds {v} (Gene) CYP2C9
Haloperidol {u} (Compound) palliates {v} (Disease) schizophrenia
Haloperidol {u} (Compound) downregulates {v} (Gene) CDC20
Haloperidol {u} (Compound) causes {v} (Side Effect) Extrapyramidal disorder
Haloperidol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metronidazole
Haloperidol {u} may lead to a major life threatening interaction when taken with {v} Anagrelide
Haloperidol (Compound) resembles Bepotastine (Compound)
Haloperidol may cause a moderate interaction that could exacerbate diseases when taken with Loperamide
Haloperidol (Compound) resembles Sertindole (Compound)
Haloperidol may cause a moderate interaction that could exacerbate diseases when taken with Cetirizine
Haloperidol (Compound) binds CYP2C9 (Gene)
Haloperidol (Compound) palliates schizophrenia (Disease)
Haloperidol (Compound) downregulates CDC20 (Gene)
Haloperidol (Compound) causes Extrapyramidal disorder (Side Effect)
Haloperidol may cause a minor interaction that can limit clinical effects when taken with Metronidazole
Haloperidol may lead to a major life threatening interaction when taken with Anagrelide