DDInter1866 DDInter154
A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.
Azelastine is a phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position. It has a role as a H1-receptor antagonist, an anti-allergic agent, an anti-asthmatic drug, a bronchodilator agent, a platelet aggregation inhibitor and an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. It is a member of phthalazines, a tertiary amino compound and a member of monochlorobenzenes.
Trifluoperazine {u} (Compound) resembles {v} (Compound) Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) Azelastine
Trifluoperazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clemastine
Clemastine {u} (Compound) resembles {v} (Compound) Azelastine
Trifluoperazine {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Azelastine
Trifluoperazine {u} (Compound) upregulates {v} (Gene) AGR2
AGR2 {u} (Gene) is upregulated by {v} (Compound) Azelastine
Trifluoperazine {u} (Compound) downregulates {v} (Gene) NOSIP
NOSIP {u} (Gene) is downregulated by {v} (Compound) Azelastine
Trifluoperazine {u} (Compound) causes {v} (Side Effect) Headache
Headache {u} (Side Effect) is caused by {v} (Compound) Azelastine
Trifluoperazine {u} (Compound) resembles {v} (Compound) Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) Prazepam
Prazepam {u} (Compound) resembles {v} (Compound) Azelastine
Trifluoperazine {u} (Compound) resembles {v} (Compound) Clozapine
Clozapine {u} (Compound) resembles {v} (Compound) Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) Azelastine
Trifluoperazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clemastine
Clemastine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) Azelastine
Trifluoperazine {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Meclizine
Meclizine {u} (Compound) resembles {v} (Compound) Azelastine
Trifluoperazine (Compound) resembles Loxapine (Compound) and Loxapine (Compound) resembles Azelastine (Compound)
Trifluoperazine may cause a moderate interaction that could exacerbate diseases when taken with Clemastine and Clemastine (Compound) resembles Azelastine (Compound)
Trifluoperazine (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Azelastine (Compound)
Trifluoperazine (Compound) upregulates AGR2 (Gene) and AGR2 (Gene) is upregulated by Azelastine (Compound)
Trifluoperazine (Compound) downregulates NOSIP (Gene) and NOSIP (Gene) is downregulated by Azelastine (Compound)
Trifluoperazine (Compound) causes Headache (Side Effect) and Headache (Side Effect) is caused by Azelastine (Compound)
Trifluoperazine (Compound) resembles Loxapine (Compound) and Loxapine (Compound) resembles Prazepam (Compound) and Prazepam (Compound) resembles Azelastine (Compound)
Trifluoperazine (Compound) resembles Clozapine (Compound) and Clozapine (Compound) resembles Loxapine (Compound) and Loxapine (Compound) resembles Azelastine (Compound)
Trifluoperazine may cause a moderate interaction that could exacerbate diseases when taken with Clemastine and Clemastine may cause a moderate interaction that could exacerbate diseases when taken with Loxapine and Loxapine (Compound) resembles Azelastine (Compound)
Trifluoperazine (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Meclizine (Compound) and Meclizine (Compound) resembles Azelastine (Compound)