DDInter644 DDInter1853
A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin A] (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant, and free radical-scavenging activities. It has been used in dermatology for many years to treat various skin conditions ranging from acne to wrinkles [A257474,A258185] and activates nuclear receptors to regulate epithelial cell growth and differentiation.[A257474,A257629,A257609] Tretinoin is given orally to treat acute promyelocytic leukemia and topically to treat skin conditions such as acne.[L45389,L34869,L45384]
Enoxacin {u} (Compound) upregulates {v} (Gene) HERC6
HERC6 {u} (Gene) is upregulated by {v} (Compound) Tretinoin
Enoxacin {u} (Compound) upregulates {v} (Gene) CEBPA
CEBPA {u} (Gene) is downregulated by {v} (Compound) Tretinoin
Enoxacin {u} (Compound) upregulates {v} (Gene) HERC6
HERC6 {u} (Gene) is upregulated by {v} (Compound) Isotretinoin
Isotretinoin {u} (Compound) resembles {v} (Compound) Tretinoin
Enoxacin {u} (Compound) resembles {v} (Compound) Levofloxacin
Levofloxacin {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Tretinoin
Enoxacin {u} (Compound) upregulates {v} (Gene) CEBPA
CEBPA {u} (Gene) is downregulated by {v} (Compound) Isotretinoin
Isotretinoin {u} (Compound) resembles {v} (Compound) Tretinoin
Enoxacin {u} (Compound) resembles {v} (Compound) Besifloxacin
Besifloxacin {u} (Compound) causes {v} (Side Effect) Headache
Headache {u} (Side Effect) is caused by {v} (Compound) Tretinoin
Enoxacin {u} (Compound) resembles {v} (Compound) Levofloxacin
Levofloxacin {u} (Compound) downregulates {v} (Gene) ALAS1
ALAS1 {u} (Gene) is upregulated by {v} (Compound) Tretinoin
Enoxacin {u} (Compound) upregulates {v} (Gene) HERC6
HERC6 {u} (Gene) is regulated by {v} (Gene) CYP1A1
CYP1A1 {u} (Gene) is bound by {v} (Compound) Tretinoin
Enoxacin {u} (Compound) resembles {v} (Compound) Levofloxacin
Levofloxacin {u} (Compound) downregulates {v} (Gene) TRIB3
TRIB3 {u} (Gene) is downregulated by {v} (Compound) Tretinoin
Enoxacin {u} (Compound) upregulates {v} (Gene) CEBPA
CEBPA {u} (Gene) interacts with {v} (Gene) RARB
RARB {u} (Gene) is bound by {v} (Compound) Tretinoin
Enoxacin (Compound) upregulates HERC6 (Gene) and HERC6 (Gene) is upregulated by Tretinoin (Compound)
Enoxacin (Compound) upregulates CEBPA (Gene) and CEBPA (Gene) is downregulated by Tretinoin (Compound)
Enoxacin (Compound) upregulates HERC6 (Gene) and HERC6 (Gene) is upregulated by Isotretinoin (Compound) and Isotretinoin (Compound) resembles Tretinoin (Compound)
Enoxacin (Compound) resembles Levofloxacin (Compound) and Levofloxacin (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Tretinoin (Compound)
Enoxacin (Compound) upregulates CEBPA (Gene) and CEBPA (Gene) is downregulated by Isotretinoin (Compound) and Isotretinoin (Compound) resembles Tretinoin (Compound)
Enoxacin (Compound) resembles Besifloxacin (Compound) and Besifloxacin (Compound) causes Headache (Side Effect) and Headache (Side Effect) is caused by Tretinoin (Compound)
Enoxacin (Compound) resembles Levofloxacin (Compound) and Levofloxacin (Compound) downregulates ALAS1 (Gene) and ALAS1 (Gene) is upregulated by Tretinoin (Compound)
Enoxacin (Compound) upregulates HERC6 (Gene) and HERC6 (Gene) is regulated by CYP1A1 (Gene) and CYP1A1 (Gene) is bound by Tretinoin (Compound)
Enoxacin (Compound) resembles Levofloxacin (Compound) and Levofloxacin (Compound) downregulates TRIB3 (Gene) and TRIB3 (Gene) is downregulated by Tretinoin (Compound)
Enoxacin (Compound) upregulates CEBPA (Gene) and CEBPA (Gene) interacts with RARB (Gene) and RARB (Gene) is bound by Tretinoin (Compound)