DDInter986 DDInter178
Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Bendamustine is a nitrogen mustard drug indicated for use in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed during or within six months of treatment with rituximab or a rituximab-containing regimen. Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases resulting in cell death. It is active against both active and quiescent cells, although the exact mechanism of action is unknown.
Isoniazid {u} (Compound) binds {v} (Gene) CYP3A4
Isoniazid {u} (Compound) causes {v} (Side Effect) Pyridoxine deficiency
Isoniazid {u} may cause a minor interaction that can limit clinical effects when taken with {v} Methylprednisolone
Isoniazid {u} may cause a minor interaction that can limit clinical effects when taken with {v} Fludrocortisone
Isoniazid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pioglitazone
Isoniazid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Theophylline
Isoniazid {u} may lead to a major life threatening interaction when taken with {v} Leflunomide
Isoniazid (Compound) binds CYP3A4 (Gene)
Isoniazid (Compound) causes Pyridoxine deficiency (Side Effect)
Isoniazid may cause a minor interaction that can limit clinical effects when taken with Methylprednisolone
Isoniazid may cause a minor interaction that can limit clinical effects when taken with Fludrocortisone
Isoniazid may cause a moderate interaction that could exacerbate diseases when taken with Pioglitazone
Isoniazid may cause a moderate interaction that could exacerbate diseases when taken with Theophylline
Isoniazid may lead to a major life threatening interaction when taken with Leflunomide