DDInter293 DDInter1376
Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965. Aside from the above uses, this drug is also given to control the symptoms of bipolar 1. Interestingly, carbamazepine was the first anticonvulsant used to treat individuals with bipolar disorder.
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26, 2020.[L12573,L12582] The US approval was followed by the approval in Canada on October 2, 2020. In November 2021, ozanimod was also approved by the European Commission for the treatment of adults with relapsing remitting multiple sclerosis.[L39377,L39382] MS is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Inflammatory bowel disease also a chronic inflammatory condition and can cause persistent abdominal pain, diarrhea, bloody stools, and vomiting. In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard in MS therapy. Studies involving patients with inflammatory bowel disease have also shown promising results.[A189318,A189342]
Carbamazepine {u} (Compound) resembles {v} (Compound) Magnesium salicylate
Carbamazepine {u} (Compound) resembles {v} (Compound) Modafinil
Carbamazepine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methdilazine
Carbamazepine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cyproheptadine
Carbamazepine {u} (Compound) treats {v} (Disease) epilepsy syndrome
Carbamazepine {u} (Compound) binds {v} (Gene) SCN9A
Carbamazepine {u} (Compound) upregulates {v} (Gene) PLCB3
Carbamazepine {u} (Compound) palliates {v} (Disease) bipolar disorder
Carbamazepine {u} (Compound) is included by {v} (Pharmacologic Class) Cytochrome P450 1A2 Inducers
Carbamazepine {u} (Compound) downregulates {v} (Gene) TIMM9
Carbamazepine (Compound) resembles Magnesium salicylate (Compound)
Carbamazepine (Compound) resembles Modafinil (Compound)
Carbamazepine may cause a moderate interaction that could exacerbate diseases when taken with Methdilazine
Carbamazepine may cause a moderate interaction that could exacerbate diseases when taken with Cyproheptadine
Carbamazepine (Compound) treats epilepsy syndrome (Disease)
Carbamazepine (Compound) binds SCN9A (Gene)
Carbamazepine (Compound) upregulates PLCB3 (Gene)
Carbamazepine (Compound) palliates bipolar disorder (Disease)
Carbamazepine (Compound) is included by Cytochrome P450 1A2 Inducers (Pharmacologic Class)
Carbamazepine (Compound) downregulates TIMM9 (Gene)