DDInter1031 DDInter1113
Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients. Treatment options for chronic Hepatitis C have advanced significantly since 2011, with the development of Direct Acting Antivirals (DAAs) such as ledipasvir. More specifically, ledipasvir is an inhibitor of the Hepatitis C Virus (HCV) Non-Structural Protein 5A (NS5A), which is required for viral RNA replication and assembly of HCV virions. Although its exact mechanism of action is unknown, it is postulated to prevent hyperphosphorylation of NS5A which is required
Magnesium carbonate, also known as magnesite, is a common over the counter remedy for heartburn and upset stomach caused by overproduction of acid in the stomach [FDA Label].
Magnesium carbonate {u} may cause a minor interaction that can limit clinical effects when taken with {v} Perindopril
Magnesium carbonate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tetracycline
Magnesium carbonate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ferrous sulfate anhydrous
Magnesium carbonate {u} may lead to a major life threatening interaction when taken with {v} Erdafitinib
Magnesium carbonate {u} may lead to a major life threatening interaction when taken with {v} Dolutegravir
Magnesium carbonate may cause a minor interaction that can limit clinical effects when taken with Perindopril
Magnesium carbonate may cause a moderate interaction that could exacerbate diseases when taken with Tetracycline
Magnesium carbonate may cause a moderate interaction that could exacerbate diseases when taken with Ferrous sulfate anhydrous
Magnesium carbonate may lead to a major life threatening interaction when taken with Erdafitinib
Magnesium carbonate may lead to a major life threatening interaction when taken with Dolutegravir