DDInter1259 DDInter1378
Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Paclitaxel can cause developmental toxicity, female reproductive toxicity and male reproductive toxicity according to state or federal government labeling requirements.
Nalidixic acid {u} (Compound) downregulates {v} (Gene) SLC5A6
SLC5A6 {u} (Gene) is downregulated by {v} (Compound) Paclitaxel
Nalidixic acid {u} (Compound) causes {v} (Side Effect) Swelling
Swelling {u} (Side Effect) is caused by {v} (Compound) Paclitaxel
Nalidixic acid {u} (Compound) resembles {v} (Compound) Enoxacin
Enoxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Paclitaxel
Nalidixic acid {u} (Compound) resembles {v} (Compound) Norfloxacin
Norfloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Paclitaxel
Nalidixic acid {u} (Compound) downregulates {v} (Gene) SLC5A6
SLC5A6 {u} (Gene) regulates {v} (Gene) MMP1
MMP1 {u} (Gene) is upregulated by {v} (Compound) Paclitaxel
Nalidixic acid {u} (Compound) causes {v} (Side Effect) Swelling
Swelling {u} (Side Effect) is caused by {v} (Compound) Docetaxel
Docetaxel {u} (Compound) resembles {v} (Compound) Paclitaxel
Nalidixic acid {u} (Compound) causes {v} (Side Effect) Arthralgia
Arthralgia {u} (Side Effect) is caused by {v} (Compound) Cabazitaxel
Cabazitaxel {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Paclitaxel
Nalidixic acid {u} (Compound) causes {v} (Side Effect) Urticaria
Urticaria {u} (Side Effect) is caused by {v} (Compound) Sparfloxacin
Sparfloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Paclitaxel
Nalidixic acid {u} (Compound) resembles {v} (Compound) Enoxacin
Enoxacin {u} (Compound) downregulates {v} (Gene) DLD
DLD {u} (Gene) is downregulated by {v} (Compound) Paclitaxel
Nalidixic acid {u} (Compound) resembles {v} (Compound) Norfloxacin
Norfloxacin {u} (Compound) binds {v} (Gene) CYP3A5
CYP3A5 {u} (Gene) is bound by {v} (Compound) Paclitaxel
Nalidixic acid (Compound) downregulates SLC5A6 (Gene) and SLC5A6 (Gene) is downregulated by Paclitaxel (Compound)
Nalidixic acid (Compound) causes Swelling (Side Effect) and Swelling (Side Effect) is caused by Paclitaxel (Compound)
Nalidixic acid (Compound) resembles Enoxacin (Compound) and Enoxacin may cause a minor interaction that can limit clinical effects when taken with Paclitaxel
Nalidixic acid (Compound) resembles Norfloxacin (Compound) and Norfloxacin may cause a minor interaction that can limit clinical effects when taken with Paclitaxel
Nalidixic acid (Compound) downregulates SLC5A6 (Gene) and SLC5A6 (Gene) regulates MMP1 (Gene) and MMP1 (Gene) is upregulated by Paclitaxel (Compound)
Nalidixic acid (Compound) causes Swelling (Side Effect) and Swelling (Side Effect) is caused by Docetaxel (Compound) and Docetaxel (Compound) resembles Paclitaxel (Compound)
Nalidixic acid (Compound) causes Arthralgia (Side Effect) and Arthralgia (Side Effect) is caused by Cabazitaxel (Compound) and Cabazitaxel may cause a moderate interaction that could exacerbate diseases when taken with Paclitaxel
Nalidixic acid (Compound) causes Urticaria (Side Effect) and Urticaria (Side Effect) is caused by Sparfloxacin (Compound) and Sparfloxacin may cause a minor interaction that can limit clinical effects when taken with Paclitaxel
Nalidixic acid (Compound) resembles Enoxacin (Compound) and Enoxacin (Compound) downregulates DLD (Gene) and DLD (Gene) is downregulated by Paclitaxel (Compound)
Nalidixic acid (Compound) resembles Norfloxacin (Compound) and Norfloxacin (Compound) binds CYP3A5 (Gene) and CYP3A5 (Gene) is bound by Paclitaxel (Compound)