DDInter1662 DDInter45
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before beneficial effects are noticed. Sertraline displays enhanced safety or tolerability than other classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and other undesirable effects.[A1846,A187075,T28]
A phenothiazine derivative that is used as an antipruritic.
Sertraline {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Alimemazine
Sertraline {u} (Compound) upregulates {v} (Gene) IDI1
IDI1 {u} (Gene) is upregulated by {v} (Compound) Alimemazine
Sertraline {u} (Compound) downregulates {v} (Gene) CYCS
CYCS {u} (Gene) is downregulated by {v} (Compound) Alimemazine
Sertraline {u} (Compound) causes {v} (Side Effect) Tremor
Tremor {u} (Side Effect) is caused by {v} (Compound) Alimemazine
Sertraline {u} (Compound) resembles {v} (Compound) Maprotiline
Maprotiline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Alimemazine
Sertraline {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Orphenadrine
Orphenadrine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Alimemazine
Sertraline {u} (Compound) upregulates {v} (Gene) IDI1
IDI1 {u} (Gene) is regulated by {v} (Gene) CCDC86
CCDC86 {u} (Gene) is downregulated by {v} (Compound) Alimemazine
Sertraline {u} (Compound) upregulates {v} (Gene) ACAT2
ACAT2 {u} (Gene) is upregulated by {v} (Compound) Chlorprothixene
Chlorprothixene {u} (Compound) resembles {v} (Compound) Alimemazine
Sertraline {u} (Compound) upregulates {v} (Gene) FOXO4
FOXO4 {u} (Gene) is upregulated by {v} (Compound) Promazine
Promazine {u} (Compound) resembles {v} (Compound) Alimemazine
Sertraline {u} (Compound) downregulates {v} (Gene) CYCS
CYCS {u} (Gene) is downregulated by {v} (Compound) Triflupromazine
Triflupromazine {u} (Compound) resembles {v} (Compound) Alimemazine
Sertraline (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Alimemazine (Compound)
Sertraline (Compound) upregulates IDI1 (Gene) and IDI1 (Gene) is upregulated by Alimemazine (Compound)
Sertraline (Compound) downregulates CYCS (Gene) and CYCS (Gene) is downregulated by Alimemazine (Compound)
Sertraline (Compound) causes Tremor (Side Effect) and Tremor (Side Effect) is caused by Alimemazine (Compound)
Sertraline (Compound) resembles Maprotiline (Compound) and Maprotiline may cause a moderate interaction that could exacerbate diseases when taken with Alimemazine
Sertraline (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Orphenadrine (Compound) and Orphenadrine may cause a moderate interaction that could exacerbate diseases when taken with Alimemazine
Sertraline (Compound) upregulates IDI1 (Gene) and IDI1 (Gene) is regulated by CCDC86 (Gene) and CCDC86 (Gene) is downregulated by Alimemazine (Compound)
Sertraline (Compound) upregulates ACAT2 (Gene) and ACAT2 (Gene) is upregulated by Chlorprothixene (Compound) and Chlorprothixene (Compound) resembles Alimemazine (Compound)
Sertraline (Compound) upregulates FOXO4 (Gene) and FOXO4 (Gene) is upregulated by Promazine (Compound) and Promazine (Compound) resembles Alimemazine (Compound)
Sertraline (Compound) downregulates CYCS (Gene) and CYCS (Gene) is downregulated by Triflupromazine (Compound) and Triflupromazine (Compound) resembles Alimemazine (Compound)