DDInter948 DDInter769
Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It is also the first entirely synthetic HMG-CoA reductase inhibitor and is structurally distinct from the fungal derivatives of this therapeutic class. Fluvastatin is a racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin.
Fluvastatin {u} (Compound) resembles {v} (Compound) Pitavastatin
Fluvastatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Rosuvastatin
Fluvastatin {u} (Compound) binds {v} (Gene) UGT2B7
Fluvastatin {u} (Compound) upregulates {v} (Gene) ST6GALNAC2
Fluvastatin {u} (Compound) downregulates {v} (Gene) URB2
Fluvastatin {u} (Compound) causes {v} (Side Effect) Muscular weakness
Fluvastatin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Clopidogrel
Fluvastatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Epirubicin
Fluvastatin {u} may lead to a major life threatening interaction when taken with {v} Teriflunomide
Fluvastatin {u} may lead to a major life threatening interaction when taken with {v} Lenalidomide
Fluvastatin (Compound) resembles Pitavastatin (Compound)
Fluvastatin may cause a moderate interaction that could exacerbate diseases when taken with Rosuvastatin
Fluvastatin (Compound) binds UGT2B7 (Gene)
Fluvastatin (Compound) upregulates ST6GALNAC2 (Gene)
Fluvastatin (Compound) downregulates URB2 (Gene)
Fluvastatin (Compound) causes Muscular weakness (Side Effect)
Fluvastatin may cause a minor interaction that can limit clinical effects when taken with Clopidogrel
Fluvastatin may cause a moderate interaction that could exacerbate diseases when taken with Epirubicin
Fluvastatin may lead to a major life threatening interaction when taken with Teriflunomide
Fluvastatin may lead to a major life threatening interaction when taken with Lenalidomide