DDInter790 DDInter1665
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of water from the body. Furosemide has a fast onset and short duration of action and has been used safely and effectively in both pediatric and adult patients. The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential. In addition to oral formulations, the solution for intravenous and intramuscular administration is also available, which is typically limited to patients who are unable to take oral medication or for patients in emergency clinical situations.
Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the United States. In October 2010, Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease.
Furosemide {u} (Compound) causes {v} (Side Effect) Thirst
Thirst {u} (Side Effect) is caused by {v} (Compound) Sibutramine
Furosemide {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sibutramine
Furosemide {u} (Compound) causes {v} (Side Effect) Thirst
Thirst {u} (Side Effect) is caused by {v} (Compound) Fluconazole
Fluconazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Sibutramine
Furosemide {u} (Compound) causes {v} (Side Effect) Apathy
Apathy {u} (Side Effect) is caused by {v} (Compound) Primidone
Primidone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sibutramine
Furosemide {u} (Compound) causes {v} (Side Effect) Photosensitivity
Photosensitivity {u} (Side Effect) is caused by {v} (Compound) Danazol
Danazol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Sibutramine
Furosemide {u} (Compound) resembles {v} (Compound) Bumetanide
Bumetanide {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sibutramine
Furosemide {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Sibutramine
Furosemide {u} (Compound) causes {v} (Side Effect) Mental disability
Mental disability {u} (Side Effect) is caused by {v} (Compound) Phenobarbital
Phenobarbital {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sibutramine
Furosemide {u} (Compound) treats {v} (Disease) coronary artery disease
coronary artery disease {u} (Disease) is treated by {v} (Compound) Tirofiban
Tirofiban {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sibutramine
Furosemide {u} (Compound) resembles {v} (Compound) Bumetanide
Bumetanide {u} (Compound) causes {v} (Side Effect) Leukopenia
Leukopenia {u} (Side Effect) is caused by {v} (Compound) Sibutramine
Furosemide (Compound) causes Thirst (Side Effect) and Thirst (Side Effect) is caused by Sibutramine (Compound)
Furosemide (Compound) resembles Indapamide (Compound) and Indapamide may cause a moderate interaction that could exacerbate diseases when taken with Sibutramine
Furosemide (Compound) causes Thirst (Side Effect) and Thirst (Side Effect) is caused by Fluconazole (Compound) and Fluconazole may cause a minor interaction that can limit clinical effects when taken with Sibutramine
Furosemide (Compound) causes Apathy (Side Effect) and Apathy (Side Effect) is caused by Primidone (Compound) and Primidone may cause a moderate interaction that could exacerbate diseases when taken with Sibutramine
Furosemide (Compound) causes Photosensitivity (Side Effect) and Photosensitivity (Side Effect) is caused by Danazol (Compound) and Danazol may cause a minor interaction that can limit clinical effects when taken with Sibutramine
Furosemide (Compound) resembles Bumetanide (Compound) and Bumetanide (Compound) resembles Indapamide (Compound) and Indapamide may cause a moderate interaction that could exacerbate diseases when taken with Sibutramine
Furosemide (Compound) resembles Indapamide (Compound) and Indapamide (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Sibutramine (Compound)
Furosemide (Compound) causes Mental disability (Side Effect) and Mental disability (Side Effect) is caused by Phenobarbital (Compound) and Phenobarbital may cause a moderate interaction that could exacerbate diseases when taken with Sibutramine
Furosemide (Compound) treats coronary artery disease (Disease) and coronary artery disease (Disease) is treated by Tirofiban (Compound) and Tirofiban may cause a moderate interaction that could exacerbate diseases when taken with Sibutramine
Furosemide (Compound) resembles Bumetanide (Compound) and Bumetanide (Compound) causes Leukopenia (Side Effect) and Leukopenia (Side Effect) is caused by Sibutramine (Compound)