DDInter1627 DDInter1053
Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. Clinical trials suggest its efficacy in the treatment of partial seizures.
Levocetirizine is a selective histamine H<sub>1</sub> antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of [cetirizine]. Levocetirizine has greater affinity for the histamine H<sub>1</sub> receptor than cetirizine. Levocetirizine was granted FDA approval in 1995.
Rufinamide {u} (Compound) treats {v} (Disease) epilepsy syndrome
epilepsy syndrome {u} (Disease) is treated by {v} (Compound) Levetiracetam
Levetiracetam {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Levocetirizine
Rufinamide {u} (Compound) binds {v} (Gene) SCN7A
SCN7A {u} (Gene) is bound by {v} (Compound) Ethotoin
Ethotoin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Levocetirizine
Rufinamide {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Theophylline
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Levocetirizine
Rufinamide {u} (Compound) causes {v} (Side Effect) Mental disorder
Mental disorder {u} (Side Effect) is caused by {v} (Compound) Tapentadol
Tapentadol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Levocetirizine
Rufinamide {u} (Compound) causes {v} (Side Effect) Rash
Rash {u} (Side Effect) is caused by {v} (Compound) Theophylline
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Levocetirizine
Rufinamide {u} (Compound) causes {v} (Side Effect) Atrioventricular block first degree
Atrioventricular block first degree {u} (Side Effect) is caused by {v} (Compound) Lurasidone
Lurasidone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Levocetirizine
Rufinamide {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Lurasidone
Lurasidone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Levocetirizine
Rufinamide (Compound) treats epilepsy syndrome (Disease) and epilepsy syndrome (Disease) is treated by Levetiracetam (Compound) and Levetiracetam may cause a moderate interaction that could exacerbate diseases when taken with Levocetirizine
Rufinamide (Compound) binds SCN7A (Gene) and SCN7A (Gene) is bound by Ethotoin (Compound) and Ethotoin may cause a moderate interaction that could exacerbate diseases when taken with Levocetirizine
Rufinamide (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Theophylline (Compound) and Theophylline may cause a minor interaction that can limit clinical effects when taken with Levocetirizine
Rufinamide (Compound) causes Mental disorder (Side Effect) and Mental disorder (Side Effect) is caused by Tapentadol (Compound) and Tapentadol may cause a moderate interaction that could exacerbate diseases when taken with Levocetirizine
Rufinamide (Compound) causes Rash (Side Effect) and Rash (Side Effect) is caused by Theophylline (Compound) and Theophylline may cause a minor interaction that can limit clinical effects when taken with Levocetirizine
Rufinamide (Compound) causes Atrioventricular block first degree (Side Effect) and Atrioventricular block first degree (Side Effect) is caused by Lurasidone (Compound) and Lurasidone may cause a moderate interaction that could exacerbate diseases when taken with Levocetirizine
Rufinamide (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Lurasidone (Compound) and Lurasidone may cause a moderate interaction that could exacerbate diseases when taken with Levocetirizine