DDInter1875 DDInter1692
A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against pneumocystis pneumonia in AIDS patients. Myelosuppression is its dose-limiting toxic effect.
Sodium dihydrogenphosphate is a sodium phosphate.
Trimetrexate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Picosulfuric acid
Picosulfuric acid {u} may cause a minor interaction that can limit clinical effects when taken with {v} Linaclotide
Linaclotide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Sodium phosphate, monobasic
Trimetrexate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Idelalisib
Idelalisib {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Linaclotide
Linaclotide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Sodium phosphate, monobasic
Trimetrexate {u} (Compound) causes {v} (Side Effect) Asthenia
Asthenia {u} (Side Effect) is caused by {v} (Compound) Pseudoephedrine
Pseudoephedrine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Sodium phosphate, monobasic
Trimetrexate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Picosulfuric acid
Picosulfuric acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lactulose
Lactulose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sodium phosphate, monobasic
Trimetrexate {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Lactulose
Lactulose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sodium phosphate, monobasic
Trimetrexate {u} may lead to a major life threatening interaction when taken with {v} Clozapine
Clozapine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lactulose
Lactulose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sodium phosphate, monobasic
Trimetrexate {u} may cause a minor interaction that can limit clinical effects when taken with {v} Fluconazole
Fluconazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lactulose
Lactulose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sodium phosphate, monobasic
Trimetrexate may cause a moderate interaction that could exacerbate diseases when taken with Picosulfuric acid and Picosulfuric acid may cause a minor interaction that can limit clinical effects when taken with Linaclotide and Linaclotide may cause a minor interaction that can limit clinical effects when taken with Sodium phosphate, monobasic
Trimetrexate may cause a moderate interaction that could exacerbate diseases when taken with Idelalisib and Idelalisib may cause a moderate interaction that could exacerbate diseases when taken with Linaclotide and Linaclotide may cause a minor interaction that can limit clinical effects when taken with Sodium phosphate, monobasic
Trimetrexate (Compound) causes Asthenia (Side Effect) and Asthenia (Side Effect) is caused by Pseudoephedrine (Compound) and Pseudoephedrine may cause a minor interaction that can limit clinical effects when taken with Sodium phosphate, monobasic
Trimetrexate may cause a moderate interaction that could exacerbate diseases when taken with Picosulfuric acid and Picosulfuric acid may cause a moderate interaction that could exacerbate diseases when taken with Lactulose and Lactulose may cause a moderate interaction that could exacerbate diseases when taken with Sodium phosphate, monobasic
Trimetrexate (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Lactulose (Compound) and Lactulose may cause a moderate interaction that could exacerbate diseases when taken with Sodium phosphate, monobasic
Trimetrexate may lead to a major life threatening interaction when taken with Clozapine and Clozapine may cause a moderate interaction that could exacerbate diseases when taken with Lactulose and Lactulose may cause a moderate interaction that could exacerbate diseases when taken with Sodium phosphate, monobasic
Trimetrexate may cause a minor interaction that can limit clinical effects when taken with Fluconazole and Fluconazole may cause a moderate interaction that could exacerbate diseases when taken with Lactulose and Lactulose may cause a moderate interaction that could exacerbate diseases when taken with Sodium phosphate, monobasic