DDInter993 DDInter533
Isradipine belongs to the dihydropyridine (DHP) class of calcium channel blockers (CCBs), the most widely used class of CCBs. It is structurally related to felodipine, nifedipine, and nimodipine and is the most potent calcium-channel blocking agent of the DHP class. Isradipine binds to calcium channels with high affinity and specificity and inhibits calcium flux into cardiac and arterial smooth muscle cells. It exhibits greater selectivity towards arterial smooth muscle cells owing to alternative splicing of the alpha-1 subunit of the channel and increased prevalence of inactive channels in smooth muscle cells. Isradipine may be used to treat mild to moderate essential hypertension.
A commonly used x-ray contrast medium. As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Isradipine {u} (Compound) causes {v} (Side Effect) Cramp muscle
Cramp muscle {u} (Side Effect) is caused by {v} (Compound) Diatrizoate
Isradipine {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Iodipamide {u} (Compound) resembles {v} (Compound) Diatrizoate
Isradipine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Gadopentetic acid
Gadopentetic acid {u} (Compound) causes {v} (Side Effect) Thrombophlebitis
Thrombophlebitis {u} (Side Effect) is caused by {v} (Compound) Diatrizoate
Isradipine {u} may lead to a major life threatening interaction when taken with {v} Dolasetron
Dolasetron {u} (Compound) causes {v} (Side Effect) Thrombophlebitis
Thrombophlebitis {u} (Side Effect) is caused by {v} (Compound) Diatrizoate
Isradipine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Octreotide
Octreotide {u} (Compound) causes {v} (Side Effect) Thrombophlebitis
Thrombophlebitis {u} (Side Effect) is caused by {v} (Compound) Diatrizoate
Isradipine {u} (Compound) resembles {v} (Compound) Nifedipine
Nifedipine {u} (Compound) causes {v} (Side Effect) Cramp muscle
Cramp muscle {u} (Side Effect) is caused by {v} (Compound) Diatrizoate
Isradipine {u} (Compound) resembles {v} (Compound) Nimodipine
Nimodipine {u} (Compound) causes {v} (Side Effect) Cramp muscle
Cramp muscle {u} (Side Effect) is caused by {v} (Compound) Diatrizoate
Isradipine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Simvastatin
Simvastatin {u} (Compound) causes {v} (Side Effect) Cramp muscle
Cramp muscle {u} (Side Effect) is caused by {v} (Compound) Diatrizoate
Isradipine (Compound) causes Cramp muscle (Side Effect) and Cramp muscle (Side Effect) is caused by Diatrizoate (Compound)
Isradipine (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Iodipamide (Compound) and Iodipamide (Compound) resembles Diatrizoate (Compound)
Isradipine may cause a moderate interaction that could exacerbate diseases when taken with Gadopentetic acid and Gadopentetic acid (Compound) causes Thrombophlebitis (Side Effect) and Thrombophlebitis (Side Effect) is caused by Diatrizoate (Compound)
Isradipine may lead to a major life threatening interaction when taken with Dolasetron and Dolasetron (Compound) causes Thrombophlebitis (Side Effect) and Thrombophlebitis (Side Effect) is caused by Diatrizoate (Compound)
Isradipine may cause a moderate interaction that could exacerbate diseases when taken with Octreotide and Octreotide (Compound) causes Thrombophlebitis (Side Effect) and Thrombophlebitis (Side Effect) is caused by Diatrizoate (Compound)
Isradipine (Compound) resembles Nifedipine (Compound) and Nifedipine (Compound) causes Cramp muscle (Side Effect) and Cramp muscle (Side Effect) is caused by Diatrizoate (Compound)
Isradipine (Compound) resembles Nimodipine (Compound) and Nimodipine (Compound) causes Cramp muscle (Side Effect) and Cramp muscle (Side Effect) is caused by Diatrizoate (Compound)
Isradipine may cause a minor interaction that can limit clinical effects when taken with Simvastatin and Simvastatin (Compound) causes Cramp muscle (Side Effect) and Cramp muscle (Side Effect) is caused by Diatrizoate (Compound)