DDInter850 DDInter576
Halazepam is a _benzodiazepine_ derivative drug exerting anxiolytic, anticonvulsant, sedative, a muscle relaxing effects.[A1212, A178114] It has been shown to be less toxic than chlordiazepoxide or diazepam. This drug is no longer marketed in the United States, and was withdrawn by _Schering_, its manufacturer, in 2009.[L6226, L6229]
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.
Halazepam {u} (Compound) resembles {v} (Compound) Oxazepam
Oxazepam {u} (Compound) binds {v} (Gene) CYP3A5
CYP3A5 {u} (Gene) is bound by {v} (Compound) Disulfiram
Halazepam {u} (Compound) resembles {v} (Compound) Triazolam
Triazolam {u} (Compound) binds {v} (Gene) CYP3A5
CYP3A5 {u} (Gene) is bound by {v} (Compound) Disulfiram
Halazepam {u} (Compound) resembles {v} (Compound) Oxazepam
Oxazepam {u} (Compound) causes {v} (Side Effect) Paraesthesia
Paraesthesia {u} (Side Effect) is caused by {v} (Compound) Disulfiram
Halazepam {u} (Compound) resembles {v} (Compound) Clobazam
Clobazam {u} (Compound) causes {v} (Side Effect) Psychotic disorder
Psychotic disorder {u} (Side Effect) is caused by {v} (Compound) Disulfiram
Halazepam {u} (Compound) resembles {v} (Compound) Alprazolam
Alprazolam {u} (Compound) downregulates {v} (Gene) MYC
MYC {u} (Gene) is upregulated by {v} (Compound) Disulfiram
Halazepam {u} (Compound) resembles {v} (Compound) Alprazolam
Alprazolam {u} (Compound) upregulates {v} (Gene) KDM5A
KDM5A {u} (Gene) is upregulated by {v} (Compound) Disulfiram
Halazepam {u} (Compound) resembles {v} (Compound) Chlordiazepoxide
Chlordiazepoxide {u} (Compound) palliates {v} (Disease) alcohol dependence
alcohol dependence {u} (Disease) is treated by {v} (Compound) Disulfiram
Halazepam {u} (Compound) resembles {v} (Compound) Alprazolam
Alprazolam {u} (Compound) downregulates {v} (Gene) CD320
CD320 {u} (Gene) is downregulated by {v} (Compound) Disulfiram
Halazepam {u} (Compound) binds {v} (Gene) GABRG1
GABRG1 {u} (Gene) is associated with {v} (Disease) alcohol dependence
alcohol dependence {u} (Disease) is treated by {v} (Compound) Disulfiram
Halazepam {u} (Compound) binds {v} (Gene) GABRG1
GABRG1 {u} (Gene) covaries with {v} (Gene) and {u} (Gene) regulates {v} (Gene) CRIP1
CRIP1 {u} (Gene) is upregulated by {v} (Compound) Disulfiram
Halazepam (Compound) resembles Oxazepam (Compound) and Oxazepam (Compound) binds CYP3A5 (Gene) and CYP3A5 (Gene) is bound by Disulfiram (Compound)
Halazepam (Compound) resembles Triazolam (Compound) and Triazolam (Compound) binds CYP3A5 (Gene) and CYP3A5 (Gene) is bound by Disulfiram (Compound)
Halazepam (Compound) resembles Oxazepam (Compound) and Oxazepam (Compound) causes Paraesthesia (Side Effect) and Paraesthesia (Side Effect) is caused by Disulfiram (Compound)
Halazepam (Compound) resembles Clobazam (Compound) and Clobazam (Compound) causes Psychotic disorder (Side Effect) and Psychotic disorder (Side Effect) is caused by Disulfiram (Compound)
Halazepam (Compound) resembles Alprazolam (Compound) and Alprazolam (Compound) downregulates MYC (Gene) and MYC (Gene) is upregulated by Disulfiram (Compound)
Halazepam (Compound) resembles Alprazolam (Compound) and Alprazolam (Compound) upregulates KDM5A (Gene) and KDM5A (Gene) is upregulated by Disulfiram (Compound)
Halazepam (Compound) resembles Chlordiazepoxide (Compound) and Chlordiazepoxide (Compound) palliates alcohol dependence (Disease) and alcohol dependence (Disease) is treated by Disulfiram (Compound)
Halazepam (Compound) resembles Alprazolam (Compound) and Alprazolam (Compound) downregulates CD320 (Gene) and CD320 (Gene) is downregulated by Disulfiram (Compound)
Halazepam (Compound) binds GABRG1 (Gene) and GABRG1 (Gene) is associated with alcohol dependence (Disease) and alcohol dependence (Disease) is treated by Disulfiram (Compound)
Halazepam (Compound) binds GABRG1 (Gene) and GABRG1 (Gene) covaries with CRIP1 (Gene) and GABRG1 (Gene) regulates CRIP1 (Gene) and CRIP1 (Gene) is upregulated by Disulfiram (Compound)