DDInter1759 DDInter1252
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arterial blood pressure.[A1489,A1490] Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects.
Mycophenolic acid is a potent immunosuppressant agent that inhibits _de novo_ purine biosynthesis. It was derived from _Penicillium stoloniferum_, and has also shown antibacterial, antifungal and antiviral properties.. Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. This regimen can be used in place of the older anti-proliferative [azathioprine] due to its stronger immunosuppressive potency. However, mycophenolic acid treatment is more expensive and requires therapeutic drug monitoring to optimize efficacy and minimize toxicity.[A249180,A249185] Mycophenolic acid is available as enteric-coated tablets of delayed-release, in an effort to improve upper gastrointestinal adverse events by delaying mycophenolic acid release until it reaches the small intestine. [Mycophenolate mofetil], a prodrug of mycophenolic acid, is also prescribed to transplant recipients to prevent organ rejection.
Telmisartan {u} (Compound) causes {v} (Side Effect) Nervous system disorder
Nervous system disorder {u} (Side Effect) is caused by {v} (Compound) Mycophenolic acid
Telmisartan {u} (Compound) causes {v} (Side Effect) Nervous system disorder
Nervous system disorder {u} (Side Effect) is caused by {v} (Compound) Mycophenolate mofetil
Mycophenolate mofetil {u} (Compound) resembles {v} (Compound) Mycophenolic acid
Telmisartan {u} (Compound) causes {v} (Side Effect) Bone disorder
Bone disorder {u} (Side Effect) is caused by {v} (Compound) Sirolimus
Sirolimus {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mycophenolic acid
Telmisartan {u} (Compound) causes {v} (Side Effect) Influenza like illness
Influenza like illness {u} (Side Effect) is caused by {v} (Compound) Ofloxacin
Ofloxacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mycophenolic acid
Telmisartan {u} (Compound) causes {v} (Side Effect) Cramp muscle
Cramp muscle {u} (Side Effect) is caused by {v} (Compound) Acyclovir
Acyclovir {u} may cause a minor interaction that can limit clinical effects when taken with {v} Mycophenolic acid
Telmisartan {u} (Compound) causes {v} (Side Effect) Arthritis
Arthritis {u} (Side Effect) is caused by {v} (Compound) Iron
Iron {u} may cause a minor interaction that can limit clinical effects when taken with {v} Mycophenolic acid
Telmisartan {u} (Compound) resembles {v} (Compound) Candesartan
Candesartan {u} (Compound) downregulates {v} (Gene) PLOD3
PLOD3 {u} (Gene) is downregulated by {v} (Compound) Mycophenolic acid
Telmisartan {u} (Compound) causes {v} (Side Effect) Blood pressure increased
Blood pressure increased {u} (Side Effect) is caused by {v} (Compound) Etonogestrel
Etonogestrel {u} may lead to a major life threatening interaction when taken with {v} Mycophenolic acid
Telmisartan {u} (Compound) resembles {v} (Compound) Azilsartan medoxomil
Azilsartan medoxomil {u} (Compound) causes {v} (Side Effect) Hyperuricaemia
Hyperuricaemia {u} (Side Effect) is caused by {v} (Compound) Mycophenolic acid
Telmisartan {u} (Compound) causes {v} (Side Effect) Blood pressure increased
Blood pressure increased {u} (Side Effect) is caused by {v} (Compound) Leflunomide
Leflunomide {u} may lead to a major life threatening interaction when taken with {v} Mycophenolic acid
Telmisartan (Compound) causes Nervous system disorder (Side Effect) and Nervous system disorder (Side Effect) is caused by Mycophenolic acid (Compound)
Telmisartan (Compound) causes Nervous system disorder (Side Effect) and Nervous system disorder (Side Effect) is caused by Mycophenolate mofetil (Compound) and Mycophenolate mofetil (Compound) resembles Mycophenolic acid (Compound)
Telmisartan (Compound) causes Bone disorder (Side Effect) and Bone disorder (Side Effect) is caused by Sirolimus (Compound) and Sirolimus may cause a moderate interaction that could exacerbate diseases when taken with Mycophenolic acid
Telmisartan (Compound) causes Influenza like illness (Side Effect) and Influenza like illness (Side Effect) is caused by Ofloxacin (Compound) and Ofloxacin may cause a moderate interaction that could exacerbate diseases when taken with Mycophenolic acid
Telmisartan (Compound) causes Cramp muscle (Side Effect) and Cramp muscle (Side Effect) is caused by Acyclovir (Compound) and Acyclovir may cause a minor interaction that can limit clinical effects when taken with Mycophenolic acid
Telmisartan (Compound) causes Arthritis (Side Effect) and Arthritis (Side Effect) is caused by Iron (Compound) and Iron may cause a minor interaction that can limit clinical effects when taken with Mycophenolic acid
Telmisartan (Compound) resembles Candesartan (Compound) and Candesartan (Compound) downregulates PLOD3 (Gene) and PLOD3 (Gene) is downregulated by Mycophenolic acid (Compound)
Telmisartan (Compound) causes Blood pressure increased (Side Effect) and Blood pressure increased (Side Effect) is caused by Etonogestrel (Compound) and Etonogestrel may lead to a major life threatening interaction when taken with Mycophenolic acid
Telmisartan (Compound) resembles Azilsartan medoxomil (Compound) and Azilsartan medoxomil (Compound) causes Hyperuricaemia (Side Effect) and Hyperuricaemia (Side Effect) is caused by Mycophenolic acid (Compound)
Telmisartan (Compound) causes Blood pressure increased (Side Effect) and Blood pressure increased (Side Effect) is caused by Leflunomide (Compound) and Leflunomide may lead to a major life threatening interaction when taken with Mycophenolic acid