DDInter341 DDInter576
On August 8, 2001 the U.S. Food and Drug Administration (FDA) announced that Bayer Pharmaceutical Division voluntarily withdrew Baycol from the U.S. market, due to reports of fatal rhabdomyolysis, a severe adverse reaction from this cholesterol-lowering (lipid-lowering) product. It has also been withdrawn from the Canadian market.[A669,L43942]
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.
Cerivastatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxaliplatin
Oxaliplatin {u} (Compound) binds {v} (Gene) CYP2E1
CYP2E1 {u} (Gene) is bound by {v} (Compound) Disulfiram
Cerivastatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Epirubicin
Epirubicin {u} (Compound) upregulates {v} (Gene) CTSL
CTSL {u} (Gene) is upregulated by {v} (Compound) Disulfiram
Cerivastatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Vinorelbine
Vinorelbine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Disulfiram
Cerivastatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Epirubicin
Epirubicin {u} (Compound) downregulates {v} (Gene) FHL2
FHL2 {u} (Gene) is upregulated by {v} (Compound) Disulfiram
Cerivastatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Vinorelbine
Vinorelbine {u} (Compound) upregulates {v} (Gene) FHL2
FHL2 {u} (Gene) is upregulated by {v} (Compound) Disulfiram
Cerivastatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Hydroxychloroquine
Hydroxychloroquine {u} (Compound) causes {v} (Side Effect) Psychotic disorder
Psychotic disorder {u} (Side Effect) is caused by {v} (Compound) Disulfiram
Cerivastatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lapatinib
Lapatinib {u} (Compound) downregulates {v} (Gene) CCDC86
CCDC86 {u} (Gene) is downregulated by {v} (Compound) Disulfiram
Cerivastatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cabazitaxel
Cabazitaxel {u} (Compound) binds {v} (Gene) TUBB6
TUBB6 {u} (Gene) is upregulated by {v} (Compound) Disulfiram
Cerivastatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lapatinib
Lapatinib {u} (Compound) upregulates {v} (Gene) CCNB2
CCNB2 {u} (Gene) is downregulated by {v} (Compound) Disulfiram
Cerivastatin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lapatinib
Lapatinib {u} (Compound) binds {v} (Gene) PIK3C2B
PIK3C2B {u} (Gene) is downregulated by {v} (Compound) Disulfiram
Cerivastatin may cause a moderate interaction that could exacerbate diseases when taken with Oxaliplatin and Oxaliplatin (Compound) binds CYP2E1 (Gene) and CYP2E1 (Gene) is bound by Disulfiram (Compound)
Cerivastatin may cause a moderate interaction that could exacerbate diseases when taken with Epirubicin and Epirubicin (Compound) upregulates CTSL (Gene) and CTSL (Gene) is upregulated by Disulfiram (Compound)
Cerivastatin may cause a moderate interaction that could exacerbate diseases when taken with Vinorelbine and Vinorelbine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Disulfiram (Compound)
Cerivastatin may cause a moderate interaction that could exacerbate diseases when taken with Epirubicin and Epirubicin (Compound) downregulates FHL2 (Gene) and FHL2 (Gene) is upregulated by Disulfiram (Compound)
Cerivastatin may cause a moderate interaction that could exacerbate diseases when taken with Vinorelbine and Vinorelbine (Compound) upregulates FHL2 (Gene) and FHL2 (Gene) is upregulated by Disulfiram (Compound)
Cerivastatin may cause a moderate interaction that could exacerbate diseases when taken with Hydroxychloroquine and Hydroxychloroquine (Compound) causes Psychotic disorder (Side Effect) and Psychotic disorder (Side Effect) is caused by Disulfiram (Compound)
Cerivastatin may cause a moderate interaction that could exacerbate diseases when taken with Lapatinib and Lapatinib (Compound) downregulates CCDC86 (Gene) and CCDC86 (Gene) is downregulated by Disulfiram (Compound)
Cerivastatin may cause a moderate interaction that could exacerbate diseases when taken with Cabazitaxel and Cabazitaxel (Compound) binds TUBB6 (Gene) and TUBB6 (Gene) is upregulated by Disulfiram (Compound)
Cerivastatin may cause a moderate interaction that could exacerbate diseases when taken with Lapatinib and Lapatinib (Compound) upregulates CCNB2 (Gene) and CCNB2 (Gene) is downregulated by Disulfiram (Compound)
Cerivastatin may cause a moderate interaction that could exacerbate diseases when taken with Lapatinib and Lapatinib (Compound) binds PIK3C2B (Gene) and PIK3C2B (Gene) is downregulated by Disulfiram (Compound)