DDInter1605 DDInter1082
Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. [Paliperidone], another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone). Schizophrenia and various mood disorders are thought to be caused by an excess of dopaminergic D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways and mesocortical pathways, respectively. Risperidone is thought to reduce this overactivity through inhibition of dopaminergic D2 receptors and serotonergic 5-HT2A receptors in the brain. Risperidone binds with a very high affinity to 5-HT2A receptors, approximately 10-20 fold greater than the drug's
Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM). It is sold by Sanofi-Aventis under the brand name Adlyxin in the US and Lyxumia in the EU. Adlyxin recieved FDA approval July 28, 2016.
Risperidone {u} (Compound) resembles {v} (Compound) Dapiprazole
Risperidone {u} (Compound) binds {v} (Gene) ADRA1B
Risperidone {u} (Compound) upregulates {v} (Gene) UBQLN2
Risperidone {u} (Compound) palliates {v} (Disease) schizophrenia
Risperidone {u} (Compound) downregulates {v} (Gene) ACAT2
Risperidone {u} (Compound) causes {v} (Side Effect) Manic psychosis
Risperidone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ranitidine
Risperidone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cimetidine
Risperidone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ipratropium
Risperidone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Histrelin
Risperidone (Compound) resembles Dapiprazole (Compound)
Risperidone (Compound) binds ADRA1B (Gene)
Risperidone (Compound) upregulates UBQLN2 (Gene)
Risperidone (Compound) palliates schizophrenia (Disease)
Risperidone (Compound) downregulates ACAT2 (Gene)
Risperidone (Compound) causes Manic psychosis (Side Effect)
Risperidone may cause a minor interaction that can limit clinical effects when taken with Ranitidine
Risperidone may cause a minor interaction that can limit clinical effects when taken with Cimetidine
Risperidone may cause a moderate interaction that could exacerbate diseases when taken with Ipratropium
Risperidone may cause a moderate interaction that could exacerbate diseases when taken with Histrelin