DDInter644 DDInter336
A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in the colon. It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval in 1998. Interestingly, selective COX-2 inhibitors (especially celecoxib), have been evaluated as potential cancer chemopreventive and therapeutic drugs in clinical trials for a variety of malignancies.
Enoxacin {u} (Compound) resembles {v} (Compound) Levofloxacin
Levofloxacin {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Celecoxib
Enoxacin {u} (Compound) resembles {v} (Compound) Besifloxacin
Besifloxacin {u} (Compound) causes {v} (Side Effect) Headache
Headache {u} (Side Effect) is caused by {v} (Compound) Celecoxib
Enoxacin {u} (Compound) resembles {v} (Compound) Levofloxacin
Levofloxacin {u} (Compound) upregulates {v} (Gene) ERAP2
ERAP2 {u} (Gene) is upregulated by {v} (Compound) Celecoxib
Enoxacin {u} (Compound) resembles {v} (Compound) Trovafloxacin
Trovafloxacin {u} (Compound) causes {v} (Side Effect) Fatigue
Fatigue {u} (Side Effect) is caused by {v} (Compound) Celecoxib
Enoxacin {u} (Compound) resembles {v} (Compound) Ciprofloxacin
Ciprofloxacin {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Celecoxib
Enoxacin {u} (Compound) resembles {v} (Compound) Gatifloxacin
Gatifloxacin {u} (Compound) downregulates {v} (Gene) RBM34
RBM34 {u} (Gene) is downregulated by {v} (Compound) Celecoxib
Enoxacin {u} (Compound) binds {v} (Gene) TOP2A
TOP2A {u} (Gene) is associated with {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is palliated by {v} (Compound) Celecoxib
Enoxacin {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Etoricoxib
Etoricoxib {u} (Compound) resembles {v} (Compound) Celecoxib
Enoxacin {u} (Compound) binds {v} (Gene) TOP2A
TOP2A {u} (Gene) is regulated by {v} (Gene) PDPK1
PDPK1 {u} (Gene) is bound by {v} (Compound) Celecoxib
Enoxacin {u} (Compound) upregulates {v} (Gene) PRKCH
PRKCH {u} (Gene) interacts with {v} (Gene) PDPK1
PDPK1 {u} (Gene) is bound by {v} (Compound) Celecoxib
Enoxacin (Compound) resembles Levofloxacin (Compound) and Levofloxacin (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Celecoxib (Compound)
Enoxacin (Compound) resembles Besifloxacin (Compound) and Besifloxacin (Compound) causes Headache (Side Effect) and Headache (Side Effect) is caused by Celecoxib (Compound)
Enoxacin (Compound) resembles Levofloxacin (Compound) and Levofloxacin (Compound) upregulates ERAP2 (Gene) and ERAP2 (Gene) is upregulated by Celecoxib (Compound)
Enoxacin (Compound) resembles Trovafloxacin (Compound) and Trovafloxacin (Compound) causes Fatigue (Side Effect) and Fatigue (Side Effect) is caused by Celecoxib (Compound)
Enoxacin (Compound) resembles Ciprofloxacin (Compound) and Ciprofloxacin (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Celecoxib (Compound)
Enoxacin (Compound) resembles Gatifloxacin (Compound) and Gatifloxacin (Compound) downregulates RBM34 (Gene) and RBM34 (Gene) is downregulated by Celecoxib (Compound)
Enoxacin (Compound) binds TOP2A (Gene) and TOP2A (Gene) is associated with hematologic cancer (Disease) and hematologic cancer (Disease) is palliated by Celecoxib (Compound)
Enoxacin (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Etoricoxib (Compound) and Etoricoxib (Compound) resembles Celecoxib (Compound)
Enoxacin (Compound) binds TOP2A (Gene) and TOP2A (Gene) is regulated by PDPK1 (Gene) and PDPK1 (Gene) is bound by Celecoxib (Compound)
Enoxacin (Compound) upregulates PRKCH (Gene) and PRKCH (Gene) interacts with PDPK1 (Gene) and PDPK1 (Gene) is bound by Celecoxib (Compound)