DDInter1300 DDInter790
Nitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase. It is used in the treatment of hereditary tyrosinemia type 1. It is sold under the brand name Orfadin.
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of water from the body. Furosemide has a fast onset and short duration of action and has been used safely and effectively in both pediatric and adult patients. The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential. In addition to oral formulations, the solution for intravenous and intramuscular administration is also available, which is typically limited to patients who are unable to take oral medication or for patients in emergency clinical situations.
Nitisinone {u} (Compound) causes {v} (Side Effect) Agitation
Agitation {u} (Side Effect) is caused by {v} (Compound) Furosemide
Nitisinone {u} (Compound) causes {v} (Side Effect) Agitation
Agitation {u} (Side Effect) is caused by {v} (Compound) Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Nitisinone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxcarbazepine
Oxcarbazepine {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Nitisinone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxcarbazepine
Oxcarbazepine {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Furosemide
Nitisinone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxcarbazepine
Oxcarbazepine {u} (Compound) causes {v} (Side Effect) Irritability
Irritability {u} (Side Effect) is caused by {v} (Compound) Furosemide
Nitisinone {u} (Compound) resembles {v} (Compound) Flutamide
Flutamide {u} (Compound) causes {v} (Side Effect) Vomiting
Vomiting {u} (Side Effect) is caused by {v} (Compound) Furosemide
Nitisinone {u} (Compound) resembles {v} (Compound) Nilutamide
Nilutamide {u} (Compound) causes {v} (Side Effect) Blood creatinine increased
Blood creatinine increased {u} (Side Effect) is caused by {v} (Compound) Furosemide
Nitisinone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Modafinil
Modafinil {u} (Compound) causes {v} (Side Effect) Constipation
Constipation {u} (Side Effect) is caused by {v} (Compound) Furosemide
Nitisinone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nateglinide
Nateglinide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Nitisinone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nevirapine
Nevirapine {u} (Compound) causes {v} (Side Effect) Pancreatitis
Pancreatitis {u} (Side Effect) is caused by {v} (Compound) Furosemide
Nitisinone (Compound) causes Agitation (Side Effect) and Agitation (Side Effect) is caused by Furosemide (Compound)
Nitisinone (Compound) causes Agitation (Side Effect) and Agitation (Side Effect) is caused by Indapamide (Compound) and Indapamide (Compound) resembles Furosemide (Compound)
Nitisinone may cause a moderate interaction that could exacerbate diseases when taken with Oxcarbazepine and Oxcarbazepine (Compound) resembles Indapamide (Compound) and Indapamide (Compound) resembles Furosemide (Compound)
Nitisinone may cause a moderate interaction that could exacerbate diseases when taken with Oxcarbazepine and Oxcarbazepine (Compound) binds ALB (Gene) and ALB (Gene) is bound by Furosemide (Compound)
Nitisinone may cause a moderate interaction that could exacerbate diseases when taken with Oxcarbazepine and Oxcarbazepine (Compound) causes Irritability (Side Effect) and Irritability (Side Effect) is caused by Furosemide (Compound)
Nitisinone (Compound) resembles Flutamide (Compound) and Flutamide (Compound) causes Vomiting (Side Effect) and Vomiting (Side Effect) is caused by Furosemide (Compound)
Nitisinone (Compound) resembles Nilutamide (Compound) and Nilutamide (Compound) causes Blood creatinine increased (Side Effect) and Blood creatinine increased (Side Effect) is caused by Furosemide (Compound)
Nitisinone may cause a minor interaction that can limit clinical effects when taken with Modafinil and Modafinil (Compound) causes Constipation (Side Effect) and Constipation (Side Effect) is caused by Furosemide (Compound)
Nitisinone may cause a moderate interaction that could exacerbate diseases when taken with Nateglinide and Nateglinide may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) resembles Furosemide (Compound)
Nitisinone may cause a moderate interaction that could exacerbate diseases when taken with Nevirapine and Nevirapine (Compound) causes Pancreatitis (Side Effect) and Pancreatitis (Side Effect) is caused by Furosemide (Compound)