DDInter592 DDInter1376
Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and hypertension. Other members of this drug class include [Prazosin], [Terazosin], [Tamsulosin], and [Alfuzosin]. Because of its long-lasting effects, doxazosin can be administered once a day. It is marketed by Pfizer and was initially approved by the FDA in 1990.
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26, 2020.[L12573,L12582] The US approval was followed by the approval in Canada on October 2, 2020. In November 2021, ozanimod was also approved by the European Commission for the treatment of adults with relapsing remitting multiple sclerosis.[L39377,L39382] MS is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Inflammatory bowel disease also a chronic inflammatory condition and can cause persistent abdominal pain, diarrhea, bloody stools, and vomiting. In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard in MS therapy. Studies involving patients with inflammatory bowel disease have also shown promising results.[A189318,A189342]
Doxazosin {u} (Compound) resembles {v} (Compound) Donepezil
Doxazosin {u} (Compound) resembles {v} (Compound) Prazosin
Doxazosin {u} (Compound) treats {v} (Disease) hypertension
Doxazosin {u} (Compound) binds {v} (Gene) ABCB1
Doxazosin {u} (Compound) upregulates {v} (Gene) DENND2D
Doxazosin {u} (Compound) causes {v} (Side Effect) Ear pain
Doxazosin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Bupropion
Doxazosin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Morphine
Doxazosin (Compound) resembles Donepezil (Compound)
Doxazosin (Compound) resembles Prazosin (Compound)
Doxazosin (Compound) treats hypertension (Disease)
Doxazosin (Compound) binds ABCB1 (Gene)
Doxazosin (Compound) upregulates DENND2D (Gene)
Doxazosin (Compound) causes Ear pain (Side Effect)
Doxazosin may cause a moderate interaction that could exacerbate diseases when taken with Bupropion
Doxazosin may cause a moderate interaction that could exacerbate diseases when taken with Morphine