DDInter1513 DDInter131
Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Atezolizumab is a humanized monoclonal antibody used to prevent the interaction of PD-L1 and PD-1, removing inhibition of immune responses seen in some cancers.[A18493,L7489] This medication is reserved for patients whose tumors express PD-L1, cannot receive platinum-based chemotherapy, or whose tumors do not respond to platinum-based chemotherapy. Atezolizumab was granted FDA approval on 18 October 2016. In November 2022, the manufacturer (Genentech) voluntarily withdrew the use of atezolizumab for the treatment of urothelial carcinoma, previously approved under the FDA's Accelerated Approval Program. The rest of atezolizumab indications remain unaffected.
Prednisolone {u} (Compound) resembles {v} (Compound) Fluprednidene Acetate
Prednisolone {u} (Compound) resembles {v} (Compound) Hydrocortamate
Prednisolone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Testosterone
Prednisolone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fluoxymesterone
Prednisolone {u} (Compound) treats {v} (Disease) chronic obstructive pulmonary disease
Prednisolone {u} (Compound) binds {v} (Gene) NR3C1
Prednisolone {u} (Compound) upregulates {v} (Gene) NFKBIA
Prednisolone {u} (Compound) palliates {v} (Disease) idiopathic pulmonary fibrosis
Prednisolone {u} (Compound) is included by {v} (Pharmacologic Class) Corticosteroid Hormone Receptor Agonists
Prednisolone {u} (Compound) downregulates {v} (Gene) FHL2
Prednisolone (Compound) resembles Fluprednidene Acetate (Compound)
Prednisolone (Compound) resembles Hydrocortamate (Compound)
Prednisolone may cause a moderate interaction that could exacerbate diseases when taken with Testosterone
Prednisolone may cause a moderate interaction that could exacerbate diseases when taken with Fluoxymesterone
Prednisolone (Compound) treats chronic obstructive pulmonary disease (Disease)
Prednisolone (Compound) binds NR3C1 (Gene)
Prednisolone (Compound) upregulates NFKBIA (Gene)
Prednisolone (Compound) palliates idiopathic pulmonary fibrosis (Disease)
Prednisolone (Compound) is included by Corticosteroid Hormone Receptor Agonists (Pharmacologic Class)
Prednisolone (Compound) downregulates FHL2 (Gene)