DDInter11 DDInter1311
Acarbose is a complex oligosaccharide that acts as an inhibitor of several enzymes responsible for the breakdown of complex carbohydrates in the intestines. It inhibits both pancreatic alpha-amylase and membrane-bound alpha-glucosidases - including intestinal glucoamylase, sucrase, maltase, and isomaltase - which are responsible for the metabolism of complex starches and oligo-, tri-, and disaccharides into absorbable simple sugars.[L31633,A37868] By inhibiting the activity of these enzymes, acarbose limits the absorption of dietary carbohydrates and the subsequent postprandial increase in blood glucose and insulin levels. Acarbose is therefore used in conjunction with diet, exercise, and other pharmacotherapies for the management of blood sugar levels in patients with type 2 diabetes.[L31628,L31633] Acarbose is one of only two approved alpha-glucosidase inhibitors (the other being
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
Acarbose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Epinephrine
Epinephrine {u} (Compound) resembles {v} (Compound) Norepinephrine
Acarbose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Salbutamol
Salbutamol {u} (Compound) resembles {v} (Compound) Norepinephrine
Acarbose {u} (Compound) causes {v} (Side Effect) Vomiting
Vomiting {u} (Side Effect) is caused by {v} (Compound) Norepinephrine
Acarbose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Epinephrine
Epinephrine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methyldopa
Methyldopa {u} (Compound) resembles {v} (Compound) Norepinephrine
Acarbose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Salbutamol
Salbutamol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methyldopa
Methyldopa {u} (Compound) resembles {v} (Compound) Norepinephrine
Acarbose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Isoprenaline
Isoprenaline {u} (Compound) resembles {v} (Compound) Methyldopa
Methyldopa {u} (Compound) resembles {v} (Compound) Norepinephrine
Acarbose {u} (Compound) upregulates {v} (Gene) PAK1
PAK1 {u} (Gene) is upregulated by {v} (Compound) Methyldopa
Methyldopa {u} (Compound) resembles {v} (Compound) Norepinephrine
Acarbose {u} (Compound) causes {v} (Side Effect) Vomiting
Vomiting {u} (Side Effect) is caused by {v} (Compound) Methyldopa
Methyldopa {u} (Compound) resembles {v} (Compound) Norepinephrine
Acarbose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Salbutamol
Salbutamol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Epinephrine
Epinephrine {u} (Compound) resembles {v} (Compound) Norepinephrine
Acarbose {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenylephrine
Phenylephrine {u} (Compound) resembles {v} (Compound) Epinephrine
Epinephrine {u} (Compound) resembles {v} (Compound) Norepinephrine
Acarbose may cause a moderate interaction that could exacerbate diseases when taken with Epinephrine and Epinephrine (Compound) resembles Norepinephrine (Compound)
Acarbose may cause a moderate interaction that could exacerbate diseases when taken with Salbutamol and Salbutamol (Compound) resembles Norepinephrine (Compound)
Acarbose (Compound) causes Vomiting (Side Effect) and Vomiting (Side Effect) is caused by Norepinephrine (Compound)
Acarbose may cause a moderate interaction that could exacerbate diseases when taken with Epinephrine and Epinephrine may cause a moderate interaction that could exacerbate diseases when taken with Methyldopa and Methyldopa (Compound) resembles Norepinephrine (Compound)
Acarbose may cause a moderate interaction that could exacerbate diseases when taken with Salbutamol and Salbutamol may cause a moderate interaction that could exacerbate diseases when taken with Methyldopa and Methyldopa (Compound) resembles Norepinephrine (Compound)
Acarbose may cause a moderate interaction that could exacerbate diseases when taken with Isoprenaline and Isoprenaline (Compound) resembles Methyldopa (Compound) and Methyldopa (Compound) resembles Norepinephrine (Compound)
Acarbose (Compound) upregulates PAK1 (Gene) and PAK1 (Gene) is upregulated by Methyldopa (Compound) and Methyldopa (Compound) resembles Norepinephrine (Compound)
Acarbose (Compound) causes Vomiting (Side Effect) and Vomiting (Side Effect) is caused by Methyldopa (Compound) and Methyldopa (Compound) resembles Norepinephrine (Compound)
Acarbose may cause a moderate interaction that could exacerbate diseases when taken with Salbutamol and Salbutamol may cause a moderate interaction that could exacerbate diseases when taken with Epinephrine and Epinephrine (Compound) resembles Norepinephrine (Compound)
Acarbose may cause a moderate interaction that could exacerbate diseases when taken with Phenylephrine and Phenylephrine (Compound) resembles Epinephrine (Compound) and Epinephrine (Compound) resembles Norepinephrine (Compound)