DDInter458 DDInter664
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus _Beauveria nivea_. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
An ergot alkaloid with uterine and vascular smooth muscle contractile properties.
Cyclosporine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Ergometrine
Cyclosporine {u} (Compound) upregulates {v} (Gene) DENND2D
DENND2D {u} (Gene) is upregulated by {v} (Compound) Ergometrine
Cyclosporine {u} (Compound) causes {v} (Side Effect) Vertigo
Vertigo {u} (Side Effect) is caused by {v} (Compound) Ergometrine
Cyclosporine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Lisuride
Lisuride {u} (Compound) resembles {v} (Compound) Ergometrine
Cyclosporine {u} (Compound) upregulates {v} (Gene) DENND2D
DENND2D {u} (Gene) regulates {v} (Gene) MAL
MAL {u} (Gene) is upregulated by {v} (Compound) Ergometrine
Cyclosporine {u} (Compound) causes {v} (Side Effect) Vertigo
Vertigo {u} (Side Effect) is caused by {v} (Compound) Lisuride
Lisuride {u} (Compound) resembles {v} (Compound) Ergometrine
Cyclosporine {u} (Compound) upregulates {v} (Gene) DENND2D
DENND2D {u} (Gene) is upregulated by {v} (Compound) Vemurafenib
Vemurafenib {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ergometrine
Cyclosporine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Pazopanib
Pazopanib {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ergometrine
Cyclosporine {u} (Compound) causes {v} (Side Effect) Haematuria
Haematuria {u} (Side Effect) is caused by {v} (Compound) Pazopanib
Pazopanib {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ergometrine
Cyclosporine {u} (Compound) causes {v} (Side Effect) Cramps of lower extremities
Cramps of lower extremities {u} (Side Effect) is caused by {v} (Compound) Bicalutamide
Bicalutamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ergometrine
Cyclosporine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Ergometrine (Compound)
Cyclosporine (Compound) upregulates DENND2D (Gene) and DENND2D (Gene) is upregulated by Ergometrine (Compound)
Cyclosporine (Compound) causes Vertigo (Side Effect) and Vertigo (Side Effect) is caused by Ergometrine (Compound)
Cyclosporine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Lisuride (Compound) and Lisuride (Compound) resembles Ergometrine (Compound)
Cyclosporine (Compound) upregulates DENND2D (Gene) and DENND2D (Gene) regulates MAL (Gene) and MAL (Gene) is upregulated by Ergometrine (Compound)
Cyclosporine (Compound) causes Vertigo (Side Effect) and Vertigo (Side Effect) is caused by Lisuride (Compound) and Lisuride (Compound) resembles Ergometrine (Compound)
Cyclosporine (Compound) upregulates DENND2D (Gene) and DENND2D (Gene) is upregulated by Vemurafenib (Compound) and Vemurafenib may cause a moderate interaction that could exacerbate diseases when taken with Ergometrine
Cyclosporine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Pazopanib (Compound) and Pazopanib may cause a moderate interaction that could exacerbate diseases when taken with Ergometrine
Cyclosporine (Compound) causes Haematuria (Side Effect) and Haematuria (Side Effect) is caused by Pazopanib (Compound) and Pazopanib may cause a moderate interaction that could exacerbate diseases when taken with Ergometrine
Cyclosporine (Compound) causes Cramps of lower extremities (Side Effect) and Cramps of lower extremities (Side Effect) is caused by Bicalutamide (Compound) and Bicalutamide may cause a moderate interaction that could exacerbate diseases when taken with Ergometrine