DDInter458 DDInter306
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus _Beauveria nivea_. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc. It is typically administered intravenously. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal cell wall.
Cyclosporine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Caspofungin
Cyclosporine {u} (Compound) causes {v} (Side Effect) Lacrimation increased
Lacrimation increased {u} (Side Effect) is caused by {v} (Compound) Caspofungin
Cyclosporine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Enzalutamide
Enzalutamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Caspofungin
Cyclosporine {u} (Compound) causes {v} (Side Effect) Lacrimation increased
Lacrimation increased {u} (Side Effect) is caused by {v} (Compound) Epirubicin
Epirubicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Caspofungin
Cyclosporine {u} (Compound) causes {v} (Side Effect) Chills
Chills {u} (Side Effect) is caused by {v} (Compound) Anidulafungin
Anidulafungin {u} (Compound) resembles {v} (Compound) Caspofungin
Cyclosporine {u} (Compound) causes {v} (Side Effect) Malaise
Malaise {u} (Side Effect) is caused by {v} (Compound) Naltrexone
Naltrexone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Caspofungin
Cyclosporine {u} (Compound) causes {v} (Side Effect) Arthralgia
Arthralgia {u} (Side Effect) is caused by {v} (Compound) Micafungin
Micafungin {u} (Compound) resembles {v} (Compound) Caspofungin
Cyclosporine {u} (Compound) causes {v} (Side Effect) Gastritis
Gastritis {u} (Side Effect) is caused by {v} (Compound) Leflunomide
Leflunomide {u} may lead to a major life threatening interaction when taken with {v} Caspofungin
Cyclosporine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Bexarotene
Bexarotene {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Caspofungin
Cyclosporine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Dexamethasone
Dexamethasone {u} may lead to a major life threatening interaction when taken with {v} Caspofungin
Cyclosporine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Caspofungin (Compound)
Cyclosporine (Compound) causes Lacrimation increased (Side Effect) and Lacrimation increased (Side Effect) is caused by Caspofungin (Compound)
Cyclosporine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Enzalutamide (Compound) and Enzalutamide may cause a moderate interaction that could exacerbate diseases when taken with Caspofungin
Cyclosporine (Compound) causes Lacrimation increased (Side Effect) and Lacrimation increased (Side Effect) is caused by Epirubicin (Compound) and Epirubicin may cause a moderate interaction that could exacerbate diseases when taken with Caspofungin
Cyclosporine (Compound) causes Chills (Side Effect) and Chills (Side Effect) is caused by Anidulafungin (Compound) and Anidulafungin (Compound) resembles Caspofungin (Compound)
Cyclosporine (Compound) causes Malaise (Side Effect) and Malaise (Side Effect) is caused by Naltrexone (Compound) and Naltrexone may cause a moderate interaction that could exacerbate diseases when taken with Caspofungin
Cyclosporine (Compound) causes Arthralgia (Side Effect) and Arthralgia (Side Effect) is caused by Micafungin (Compound) and Micafungin (Compound) resembles Caspofungin (Compound)
Cyclosporine (Compound) causes Gastritis (Side Effect) and Gastritis (Side Effect) is caused by Leflunomide (Compound) and Leflunomide may lead to a major life threatening interaction when taken with Caspofungin
Cyclosporine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Bexarotene (Compound) and Bexarotene may cause a moderate interaction that could exacerbate diseases when taken with Caspofungin
Cyclosporine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Dexamethasone (Compound) and Dexamethasone may lead to a major life threatening interaction when taken with Caspofungin