DDInter216 DDInter1676
Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and is a useful alternative to non-selective β-blocker drugs in the treatment of hypertension such as [Carvedilol] and [Labetalol]. It may be used alone or in combination with other drugs to manage hypertension and can be useful in patients with chronic obstructive pulmonary disease (COPD) due to its receptor selectivity.
Siponimod, also known as _Mayzent_, by Novartis, is a new drug formulated for the management of Multiple Sclerosis (MS). It was approved by the FDA on March 26, 2019 and by Health Canada on February 20, 2020. This drug is considered a _sphingosine-1-phosphate (S1P) receptor modulator_ and is thought to play a role in suppressing the central nervous system inflammation that is associated with MS [FDA label]. Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system that is chronic and inflammatory, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of life. Symptoms may include but are not limited to fatigue, gait changes, bowel or bladder dysfunction, abnormal muscle twitching, vision disturbance, and depressing or mood swings. MS is one of the most common causes of neurological disability in young adults and is found to occur more frequently in women than in men.[A176474,L5792]
Bisoprolol {u} (Compound) resembles {v} (Compound) Acebutolol
Bisoprolol {u} (Compound) resembles {v} (Compound) Bevantolol
Bisoprolol {u} (Compound) binds {v} (Gene) CYP2D6
Bisoprolol {u} (Compound) causes {v} (Side Effect) Oropharyngeal pain
Bisoprolol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Kaolin
Bisoprolol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Sucralfate
Bisoprolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sunitinib
Bisoprolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Betamethasone
Bisoprolol {u} may lead to a major life threatening interaction when taken with {v} Dolasetron
Bisoprolol {u} may lead to a major life threatening interaction when taken with {v} Theophylline
Bisoprolol (Compound) resembles Acebutolol (Compound)
Bisoprolol (Compound) resembles Bevantolol (Compound)
Bisoprolol (Compound) binds CYP2D6 (Gene)
Bisoprolol (Compound) causes Oropharyngeal pain (Side Effect)
Bisoprolol may cause a minor interaction that can limit clinical effects when taken with Kaolin
Bisoprolol may cause a minor interaction that can limit clinical effects when taken with Sucralfate
Bisoprolol may cause a moderate interaction that could exacerbate diseases when taken with Sunitinib
Bisoprolol may cause a moderate interaction that could exacerbate diseases when taken with Betamethasone
Bisoprolol may lead to a major life threatening interaction when taken with Dolasetron
Bisoprolol may lead to a major life threatening interaction when taken with Theophylline