DDInter195 DDInter782
Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.
In April 2018, the U.S. Food and Drug Administration (FDA) and the Swiss company Helsinn approved the intravenous formulation of AKYNZEO® (NEPA, a fixed antiemetic combination of fosnetupitant, 235mg, and palonosetron, 0.25mg) as an alternative treatment option for patients experiencing chemotherapy-induced nausea and vomiting . Fosnetupitant is the pro-drug form of netupitant [FDA label]. Generally, 25% to 30% of patients with a diagnosis of cancer receive chemotherapy as a treatment modality and 70% to 80% of these patients undergoing chemotherapy treatment may experience nausea and vomiting as major side effects. Considered one of the most distressing side effects of chemotherapy, nausea and vomiting has an immense impact on the quality of life of patients receiving certain antineoplastic therapies .
Betamethasone {u} (Compound) resembles {v} (Compound) Mometasone
Betamethasone {u} (Compound) resembles {v} (Compound) Fludrocortisone
Betamethasone {u} (Compound) treats {v} (Disease) allergic rhinitis
Betamethasone {u} (Compound) binds {v} (Gene) CYP3A4
Betamethasone {u} (Compound) upregulates {v} (Gene) GSPT1
Betamethasone {u} (Compound) palliates {v} (Disease) kidney cancer
Betamethasone {u} (Compound) is included by {v} (Pharmacologic Class) Corticosteroid Hormone Receptor Agonists
Betamethasone {u} (Compound) downregulates {v} (Gene) DDIT3
Betamethasone {u} (Compound) causes {v} (Side Effect) Blindness
Betamethasone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Orciprenaline
Betamethasone (Compound) resembles Mometasone (Compound)
Betamethasone (Compound) resembles Fludrocortisone (Compound)
Betamethasone (Compound) treats allergic rhinitis (Disease)
Betamethasone (Compound) binds CYP3A4 (Gene)
Betamethasone (Compound) upregulates GSPT1 (Gene)
Betamethasone (Compound) palliates kidney cancer (Disease)
Betamethasone (Compound) is included by Corticosteroid Hormone Receptor Agonists (Pharmacologic Class)
Betamethasone (Compound) downregulates DDIT3 (Gene)
Betamethasone (Compound) causes Blindness (Side Effect)
Betamethasone may cause a minor interaction that can limit clinical effects when taken with Orciprenaline