DDInter416 DDInter732
This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s. Clotrimazole falls under the _imidazole_ category of _azole_ antifungals, possessing broad-spectrum antimycotic activity. It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers. The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain widespread acceptance for the treatment of mycotic outbreaks such as vaginal yeast infections as well as athlete's foot.
Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. It is selective for the H<sub>1</sub> receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier - this is in contrast to previous first-generation antihistamines, such as [diphenhydramine], which readily bind to off-targets that contribute to side effects such as sedation. Fexofenadine is the major active metabolite of [terfenadine] and is administered as a racemic mixture in which both enantiomers display approximately equivalent antihistamine activity.
Clotrimazole {u} (Compound) resembles {v} (Compound) Difenoxin
Difenoxin {u} (Compound) resembles {v} (Compound) Fexofenadine
Clotrimazole {u} (Compound) resembles {v} (Compound) Diphenoxylate
Diphenoxylate {u} (Compound) resembles {v} (Compound) Fexofenadine
Clotrimazole {u} (Compound) resembles {v} (Compound) Methadone
Methadone {u} (Compound) resembles {v} (Compound) Fexofenadine
Clotrimazole {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Fexofenadine
Clotrimazole {u} (Compound) causes {v} (Side Effect) Dermatitis
Dermatitis {u} (Side Effect) is caused by {v} (Compound) Fexofenadine
Clotrimazole {u} (Compound) resembles {v} (Compound) Difenoxin
Difenoxin {u} (Compound) resembles {v} (Compound) Diphenoxylate
Diphenoxylate {u} (Compound) resembles {v} (Compound) Fexofenadine
Clotrimazole {u} (Compound) resembles {v} (Compound) Diphenoxylate
Diphenoxylate {u} (Compound) resembles {v} (Compound) Difenoxin
Difenoxin {u} (Compound) resembles {v} (Compound) Fexofenadine
Clotrimazole {u} (Compound) resembles {v} (Compound) Methadone
Methadone {u} (Compound) resembles {v} (Compound) Difenoxin
Difenoxin {u} (Compound) resembles {v} (Compound) Fexofenadine
Clotrimazole {u} (Compound) resembles {v} (Compound) Loperamide
Loperamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pimozide
Pimozide {u} (Compound) resembles {v} (Compound) Fexofenadine
Clotrimazole {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Pimozide
Pimozide {u} (Compound) resembles {v} (Compound) Fexofenadine
Clotrimazole (Compound) resembles Difenoxin (Compound) and Difenoxin (Compound) resembles Fexofenadine (Compound)
Clotrimazole (Compound) resembles Diphenoxylate (Compound) and Diphenoxylate (Compound) resembles Fexofenadine (Compound)
Clotrimazole (Compound) resembles Methadone (Compound) and Methadone (Compound) resembles Fexofenadine (Compound)
Clotrimazole (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Fexofenadine (Compound)
Clotrimazole (Compound) causes Dermatitis (Side Effect) and Dermatitis (Side Effect) is caused by Fexofenadine (Compound)
Clotrimazole (Compound) resembles Difenoxin (Compound) and Difenoxin (Compound) resembles Diphenoxylate (Compound) and Diphenoxylate (Compound) resembles Fexofenadine (Compound)
Clotrimazole (Compound) resembles Diphenoxylate (Compound) and Diphenoxylate (Compound) resembles Difenoxin (Compound) and Difenoxin (Compound) resembles Fexofenadine (Compound)
Clotrimazole (Compound) resembles Methadone (Compound) and Methadone (Compound) resembles Difenoxin (Compound) and Difenoxin (Compound) resembles Fexofenadine (Compound)
Clotrimazole (Compound) resembles Loperamide (Compound) and Loperamide may cause a moderate interaction that could exacerbate diseases when taken with Pimozide and Pimozide (Compound) resembles Fexofenadine (Compound)
Clotrimazole (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Pimozide (Compound) and Pimozide (Compound) resembles Fexofenadine (Compound)