DDInter1538 DDInter1016
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose]. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. [sucrose]). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in patients with cirrhosis.[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.
Propofol {u} (Compound) resembles {v} (Compound) Fospropofol
Propofol {u} (Compound) treats {v} (Disease) epilepsy syndrome
Propofol {u} (Compound) binds {v} (Gene) CYP2B6
Propofol {u} (Compound) is included by {v} (Pharmacologic Class) General Anesthesia
Propofol {u} (Compound) downregulates {v} (Gene) NPDC1
Propofol {u} (Compound) causes {v} (Side Effect) Bronchospasm
Propofol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Dyphylline
Propofol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metronidazole
Propofol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lapatinib
Propofol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Astemizole
Propofol (Compound) resembles Fospropofol (Compound)
Propofol (Compound) treats epilepsy syndrome (Disease)
Propofol (Compound) binds CYP2B6 (Gene)
Propofol (Compound) is included by General Anesthesia (Pharmacologic Class)
Propofol (Compound) downregulates NPDC1 (Gene)
Propofol (Compound) causes Bronchospasm (Side Effect)
Propofol may cause a minor interaction that can limit clinical effects when taken with Dyphylline
Propofol may cause a minor interaction that can limit clinical effects when taken with Metronidazole
Propofol may cause a moderate interaction that could exacerbate diseases when taken with Lapatinib
Propofol may cause a moderate interaction that could exacerbate diseases when taken with Astemizole