DDInter655 DDInter690
An anthracycline which is the 4&#39;-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.
Epirubicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Propofol
Propofol {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Ethanol
Epirubicin {u} may lead to a major life threatening interaction when taken with {v} Methadone
Methadone {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Ethanol
Epirubicin {u} (Compound) resembles {v} (Compound) Doxorubicin
Doxorubicin {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Ethanol
Epirubicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tramadol
Tramadol {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Ethanol
Epirubicin {u} may lead to a major life threatening interaction when taken with {v} Cisapride
Cisapride {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Ethanol
Epirubicin {u} (Compound) upregulates {v} (Gene) ACADS
ACADS {u} (Gene) covaries with {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Ethanol
Epirubicin {u} (Compound) treats {v} (Disease) prostate cancer
prostate cancer {u} (Disease) is associated with {v} (Gene) CYP2C19
CYP2C19 {u} (Gene) is bound by {v} (Compound) Ethanol
Epirubicin {u} (Compound) downregulates {v} (Gene) STUB1
STUB1 {u} (Gene) interacts with {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Ethanol
Epirubicin {u} (Compound) binds {v} (Gene) UGT2B7
UGT2B7 {u} (Gene) interacts with {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Ethanol
Epirubicin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metronidazole
Metronidazole {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Ethanol
Epirubicin may cause a moderate interaction that could exacerbate diseases when taken with Propofol and Propofol (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Ethanol (Compound)
Epirubicin may lead to a major life threatening interaction when taken with Methadone and Methadone (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Ethanol (Compound)
Epirubicin (Compound) resembles Doxorubicin (Compound) and Doxorubicin (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Ethanol (Compound)
Epirubicin may cause a moderate interaction that could exacerbate diseases when taken with Tramadol and Tramadol (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Ethanol (Compound)
Epirubicin may lead to a major life threatening interaction when taken with Cisapride and Cisapride (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Ethanol (Compound)
Epirubicin (Compound) upregulates ACADS (Gene) and ACADS (Gene) covaries with CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Ethanol (Compound)
Epirubicin (Compound) treats prostate cancer (Disease) and prostate cancer (Disease) is associated with CYP2C19 (Gene) and CYP2C19 (Gene) is bound by Ethanol (Compound)
Epirubicin (Compound) downregulates STUB1 (Gene) and STUB1 (Gene) interacts with CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Ethanol (Compound)
Epirubicin (Compound) binds UGT2B7 (Gene) and UGT2B7 (Gene) interacts with CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Ethanol (Compound)
Epirubicin may cause a minor interaction that can limit clinical effects when taken with Metronidazole and Metronidazole (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Ethanol (Compound)