DDInter856 DDInter98
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated hepar
Anisindione is a synthetic anticoagulant and an indanedione derivative. Its anticoagulant action is mediated through the inhibition of the vitamin K-mediated gamma-carboxylation of precursor proteins that are critical in forming the formation of active procoagulation factors II, VII, IX, and X, as well as the anticoagulant proteins C and S, in the liver.
Anisindione {u} (Compound) resembles {v} (Compound) Diltiazem
Anisindione {u} (Compound) resembles {v} (Compound) Oxybenzone
Anisindione {u} (Compound) binds {v} (Gene) GGCX
Anisindione {u} may cause a minor interaction that can limit clinical effects when taken with {v} Acarbose
Anisindione {u} may cause a minor interaction that can limit clinical effects when taken with {v} Olsalazine
Anisindione {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Apalutamide
Anisindione {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amoxicillin
Anisindione {u} may lead to a major life threatening interaction when taken with {v} Defibrotide
Anisindione {u} may lead to a major life threatening interaction when taken with {v} Lepirudin
Anisindione {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} and {u} may lead to a major life threatening interaction when taken with {v} Flurbiprofen
Anisindione (Compound) resembles Diltiazem (Compound)
Anisindione (Compound) resembles Oxybenzone (Compound)
Anisindione (Compound) binds GGCX (Gene)
Anisindione may cause a minor interaction that can limit clinical effects when taken with Acarbose
Anisindione may cause a minor interaction that can limit clinical effects when taken with Olsalazine
Anisindione may cause a moderate interaction that could exacerbate diseases when taken with Apalutamide
Anisindione may cause a moderate interaction that could exacerbate diseases when taken with Amoxicillin
Anisindione may lead to a major life threatening interaction when taken with Defibrotide
Anisindione may lead to a major life threatening interaction when taken with Lepirudin
Anisindione may cause a moderate interaction that could exacerbate diseases when taken with Flurbiprofen and Anisindione may lead to a major life threatening interaction when taken with Flurbiprofen