DDInter1860 DDInter1209
Withdrawn in the United Kingdom due to risk of psychiatric adverse drug reactions. This drug continues to be available in the U.S. Internationally, triazolam is a Schedule IV drug under the Convention on Psychotropic Substances.
Miconazole is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria as well. It is widely used to treat mucosal yeast infections, including both oral and vaginal infections; although intravenous miconazole is no longer available, a wide variety of suppositories, creams, gels, and tablet-based products are available.[L14021, L14024, L14027, L14033, L14396] Miconazole is thought to act primarily through the inhibition of fungal CYP450 14α-lanosterol demethylase activity.[A203636, A203639] Miconazole was first synthesized in 1969 and first granted FDA approval on January 8, 1974, for sale by INSIGHT Pharmaceuticals as a topical cream.[A214523, L14021] It is currently available as a variety of prescription and over the counter products. Despite having been in clinical use for an extended period, resistance to miconazole among susceptible organisms is relatively low.
Triazolam {u} (Compound) binds {v} (Gene) CYP2C9
CYP2C9 {u} (Gene) is bound by {v} (Compound) Miconazole
Triazolam {u} (Compound) causes {v} (Side Effect) Dry mouth
Dry mouth {u} (Side Effect) is caused by {v} (Compound) Miconazole
Triazolam {u} (Compound) resembles {v} (Compound) Alprazolam
Alprazolam {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Miconazole
Triazolam {u} (Compound) binds {v} (Gene) CYP2C9
CYP2C9 {u} (Gene) is bound by {v} (Compound) Tioconazole
Tioconazole {u} (Compound) resembles {v} (Compound) Miconazole
Triazolam {u} (Compound) causes {v} (Side Effect) Dry mouth
Dry mouth {u} (Side Effect) is caused by {v} (Compound) Escitalopram
Escitalopram {u} may cause a minor interaction that can limit clinical effects when taken with {v} Miconazole
Triazolam {u} (Compound) causes {v} (Side Effect) Dermatitis
Dermatitis {u} (Side Effect) is caused by {v} (Compound) Oxiconazole
Oxiconazole {u} (Compound) resembles {v} (Compound) Miconazole
Triazolam {u} (Compound) causes {v} (Side Effect) Glossodynia
Glossodynia {u} (Side Effect) is caused by {v} (Compound) Buspirone
Buspirone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Miconazole
Triazolam {u} (Compound) causes {v} (Side Effect) Hypersensitivity
Hypersensitivity {u} (Side Effect) is caused by {v} (Compound) Triclosan
Triclosan {u} (Compound) resembles {v} (Compound) Miconazole
Triazolam {u} (Compound) resembles {v} (Compound) Alprazolam
Alprazolam {u} (Compound) binds {v} (Gene) CYP2C9
CYP2C9 {u} (Gene) is bound by {v} (Compound) Miconazole
Triazolam {u} (Compound) resembles {v} (Compound) Camazepam
Camazepam {u} (Compound) resembles {v} (Compound) Midazolam
Midazolam {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Miconazole
Triazolam (Compound) binds CYP2C9 (Gene) and CYP2C9 (Gene) is bound by Miconazole (Compound)
Triazolam (Compound) causes Dry mouth (Side Effect) and Dry mouth (Side Effect) is caused by Miconazole (Compound)
Triazolam (Compound) resembles Alprazolam (Compound) and Alprazolam may cause a moderate interaction that could exacerbate diseases when taken with Miconazole
Triazolam (Compound) binds CYP2C9 (Gene) and CYP2C9 (Gene) is bound by Tioconazole (Compound) and Tioconazole (Compound) resembles Miconazole (Compound)
Triazolam (Compound) causes Dry mouth (Side Effect) and Dry mouth (Side Effect) is caused by Escitalopram (Compound) and Escitalopram may cause a minor interaction that can limit clinical effects when taken with Miconazole
Triazolam (Compound) causes Dermatitis (Side Effect) and Dermatitis (Side Effect) is caused by Oxiconazole (Compound) and Oxiconazole (Compound) resembles Miconazole (Compound)
Triazolam (Compound) causes Glossodynia (Side Effect) and Glossodynia (Side Effect) is caused by Buspirone (Compound) and Buspirone may cause a moderate interaction that could exacerbate diseases when taken with Miconazole
Triazolam (Compound) causes Hypersensitivity (Side Effect) and Hypersensitivity (Side Effect) is caused by Triclosan (Compound) and Triclosan (Compound) resembles Miconazole (Compound)
Triazolam (Compound) resembles Alprazolam (Compound) and Alprazolam (Compound) binds CYP2C9 (Gene) and CYP2C9 (Gene) is bound by Miconazole (Compound)
Triazolam (Compound) resembles Camazepam (Compound) and Camazepam (Compound) resembles Midazolam (Compound) and Midazolam may cause a moderate interaction that could exacerbate diseases when taken with Miconazole