DDInter48 DDInter1112
Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints. This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals. Allopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and is frequently used in the treatment of chronic gout. It was initially approved by the FDA in 1966 and is now formulated by several manufacturers.
Magaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Magaldrate has been discontinued in the US market.
Allopurinol {u} (Compound) treats {v} (Disease) gout
gout {u} (Disease) is treated by {v} (Compound) Hydrocortisone
Hydrocortisone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magaldrate
Allopurinol {u} (Compound) causes {v} (Side Effect) Feeling abnormal
Feeling abnormal {u} (Side Effect) is caused by {v} (Compound) Hydrocortisone
Hydrocortisone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magaldrate
Allopurinol {u} (Compound) treats {v} (Disease) gout
gout {u} (Disease) is palliated by {v} (Compound) Acetylsalicylic acid
Acetylsalicylic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Magaldrate
Allopurinol {u} (Compound) causes {v} (Side Effect) Rash maculo-papular
Rash maculo-papular {u} (Side Effect) is caused by {v} (Compound) Phenytoin
Phenytoin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Magaldrate
Allopurinol {u} (Compound) causes {v} (Side Effect) Rash maculo-papular
Rash maculo-papular {u} (Side Effect) is caused by {v} (Compound) Raltegravir
Raltegravir {u} may lead to a major life threatening interaction when taken with {v} Magaldrate
Allopurinol {u} (Compound) causes {v} (Side Effect) Abdominal pain
Abdominal pain {u} (Side Effect) is caused by {v} (Compound) Bisacodyl
Bisacodyl {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Magaldrate
Allopurinol {u} (Compound) binds {v} (Gene) SLC22A8
SLC22A8 {u} (Gene) is bound by {v} (Compound) Valproic acid
Valproic acid {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magaldrate
Allopurinol {u} (Compound) binds {v} (Gene) SLC22A7
SLC22A7 {u} (Gene) is bound by {v} (Compound) Minocycline
Minocycline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Magaldrate
Allopurinol (Compound) treats gout (Disease) and gout (Disease) is treated by Hydrocortisone (Compound) and Hydrocortisone may cause a minor interaction that can limit clinical effects when taken with Magaldrate
Allopurinol (Compound) causes Feeling abnormal (Side Effect) and Feeling abnormal (Side Effect) is caused by Hydrocortisone (Compound) and Hydrocortisone may cause a minor interaction that can limit clinical effects when taken with Magaldrate
Allopurinol (Compound) treats gout (Disease) and gout (Disease) is palliated by Acetylsalicylic acid (Compound) and Acetylsalicylic acid may cause a moderate interaction that could exacerbate diseases when taken with Magaldrate
Allopurinol (Compound) causes Rash maculo-papular (Side Effect) and Rash maculo-papular (Side Effect) is caused by Phenytoin (Compound) and Phenytoin may cause a moderate interaction that could exacerbate diseases when taken with Magaldrate
Allopurinol (Compound) causes Rash maculo-papular (Side Effect) and Rash maculo-papular (Side Effect) is caused by Raltegravir (Compound) and Raltegravir may lead to a major life threatening interaction when taken with Magaldrate
Allopurinol (Compound) causes Abdominal pain (Side Effect) and Abdominal pain (Side Effect) is caused by Bisacodyl (Compound) and Bisacodyl may cause a moderate interaction that could exacerbate diseases when taken with Magaldrate
Allopurinol (Compound) binds SLC22A8 (Gene) and SLC22A8 (Gene) is bound by Valproic acid (Compound) and Valproic acid may cause a minor interaction that can limit clinical effects when taken with Magaldrate
Allopurinol (Compound) binds SLC22A7 (Gene) and SLC22A7 (Gene) is bound by Minocycline (Compound) and Minocycline may cause a moderate interaction that could exacerbate diseases when taken with Magaldrate