DDInter150 DDInter1473
Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index.[A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of renal transplant rejection. Azathiprine was granted FDA approval on 20 March 1968.
Pipecuronium is a piperazinyl androstane derivative which is a non-depolarizing neuromuscular blocking agent.
Azathioprine {u} (Compound) causes {v} (Side Effect) Rash
Rash {u} (Side Effect) is caused by {v} (Compound) Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Azathioprine {u} (Compound) causes {v} (Side Effect) Rash
Rash {u} (Side Effect) is caused by {v} (Compound) Rocuronium
Rocuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Azathioprine {u} (Compound) treats {v} (Disease) multiple sclerosis
multiple sclerosis {u} (Disease) is associated with {v} (Gene) BCHE
BCHE {u} (Gene) is bound by {v} (Compound) Pipecuronium
Azathioprine (Compound) causes Rash (Side Effect) and Rash (Side Effect) is caused by Pancuronium (Compound) and Pancuronium (Compound) resembles Pipecuronium (Compound)
Azathioprine (Compound) causes Rash (Side Effect) and Rash (Side Effect) is caused by Rocuronium (Compound) and Rocuronium (Compound) resembles Pipecuronium (Compound)
Azathioprine (Compound) treats multiple sclerosis (Disease) and multiple sclerosis (Disease) is associated with BCHE (Gene) and BCHE (Gene) is bound by Pipecuronium (Compound)