DDInter1420 DDInter698
Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid]. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and [risedronic acid]. Etidronic acid was granted FDA approval on 1 September 1977.
Pentamidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ibandronate
Ibandronate {u} (Compound) resembles {v} (Compound) Etidronic acid
Pentamidine {u} (Compound) downregulates {v} (Gene) ACAT2
ACAT2 {u} (Gene) is downregulated by {v} (Compound) Etidronic acid
Pentamidine {u} (Compound) causes {v} (Side Effect) Confusional state
Confusional state {u} (Side Effect) is caused by {v} (Compound) Etidronic acid
Pentamidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ibandronate
Ibandronate {u} (Compound) resembles {v} (Compound) Risedronic acid
Risedronic acid {u} (Compound) resembles {v} (Compound) Etidronic acid
Pentamidine {u} (Compound) downregulates {v} (Gene) ACAT2
ACAT2 {u} (Gene) regulates {v} (Gene) SERPINA3
SERPINA3 {u} (Gene) is upregulated by {v} (Compound) Etidronic acid
Pentamidine {u} (Compound) downregulates {v} (Gene) JMJD6
JMJD6 {u} (Gene) is regulated by {v} (Gene) XBP1
XBP1 {u} (Gene) is upregulated by {v} (Compound) Etidronic acid
Pentamidine {u} (Compound) causes {v} (Side Effect) Confusional state
Confusional state {u} (Side Effect) is caused by {v} (Compound) Pamidronic acid
Pamidronic acid {u} (Compound) resembles {v} (Compound) Etidronic acid
Pentamidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ibandronate
Ibandronate {u} (Compound) resembles {v} (Compound) Pamidronic acid
Pamidronic acid {u} (Compound) resembles {v} (Compound) Etidronic acid
Pentamidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pamidronic acid
Pamidronic acid {u} (Compound) resembles {v} (Compound) Clodronate
Clodronate {u} (Compound) resembles {v} (Compound) Etidronic acid
Pentamidine {u} (Compound) downregulates {v} (Gene) ACAT2
ACAT2 {u} (Gene) regulates {v} (Gene) MRPS16
MRPS16 {u} (Gene) is downregulated by {v} (Compound) Etidronic acid
Pentamidine may cause a moderate interaction that could exacerbate diseases when taken with Ibandronate and Ibandronate (Compound) resembles Etidronic acid (Compound)
Pentamidine (Compound) downregulates ACAT2 (Gene) and ACAT2 (Gene) is downregulated by Etidronic acid (Compound)
Pentamidine (Compound) causes Confusional state (Side Effect) and Confusional state (Side Effect) is caused by Etidronic acid (Compound)
Pentamidine may cause a moderate interaction that could exacerbate diseases when taken with Ibandronate and Ibandronate (Compound) resembles Risedronic acid (Compound) and Risedronic acid (Compound) resembles Etidronic acid (Compound)
Pentamidine (Compound) downregulates ACAT2 (Gene) and ACAT2 (Gene) regulates SERPINA3 (Gene) and SERPINA3 (Gene) is upregulated by Etidronic acid (Compound)
Pentamidine (Compound) downregulates JMJD6 (Gene) and JMJD6 (Gene) is regulated by XBP1 (Gene) and XBP1 (Gene) is upregulated by Etidronic acid (Compound)
Pentamidine (Compound) causes Confusional state (Side Effect) and Confusional state (Side Effect) is caused by Pamidronic acid (Compound) and Pamidronic acid (Compound) resembles Etidronic acid (Compound)
Pentamidine may cause a moderate interaction that could exacerbate diseases when taken with Ibandronate and Ibandronate (Compound) resembles Pamidronic acid (Compound) and Pamidronic acid (Compound) resembles Etidronic acid (Compound)
Pentamidine may cause a moderate interaction that could exacerbate diseases when taken with Pamidronic acid and Pamidronic acid (Compound) resembles Clodronate (Compound) and Clodronate (Compound) resembles Etidronic acid (Compound)
Pentamidine (Compound) downregulates ACAT2 (Gene) and ACAT2 (Gene) regulates MRPS16 (Gene) and MRPS16 (Gene) is downregulated by Etidronic acid (Compound)