DDInter1123 DDInter1554
Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain and cerebrospinal fluid, into interstitial fluid and plasma. As a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure may be reduced. Mannitol may also be used for the promotion of diuresis before irreversible renal failure becomes established; the promotion of urinary excretion of toxic substances; as an Antiglaucoma agent; and as a renal function diagnostic aid. On October 30, 2020, mannitol was approved by the FDA as add-on maintenance therapy for the control of pulmonary symptoms associated with cystic fibrosis in adult patients and is currently marketed for this indication under the name BRONCHITOL® by Chies
Quinapril is the ethyl ester prodrug of the non-sulfhydryl angiotensin converting enzyme inhibitor quinaprilat.[L8420,L8423] It is used to treat hypertension and heart failure.[L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. Quinapril was granted FDA approval on 19 November 1991. A combination tablet with [hydrochlorothiazide] was also approved on 28 December 1999.
Mannitol {u} (Compound) causes {v} (Side Effect) Skin disorder
Skin disorder {u} (Side Effect) is caused by {v} (Compound) Quinapril
Mannitol {u} (Compound) causes {v} (Side Effect) Skin disorder
Skin disorder {u} (Side Effect) is caused by {v} (Compound) Trandolapril
Trandolapril {u} (Compound) resembles {v} (Compound) Quinapril
Mannitol {u} (Compound) resembles {v} (Compound) Calcium glucoheptonate
Calcium glucoheptonate {u} (Compound) causes {v} (Side Effect) Diarrhoea
Diarrhoea {u} (Side Effect) is caused by {v} (Compound) Quinapril
Mannitol {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Sirolimus
Sirolimus {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Quinapril
Mannitol {u} (Compound) causes {v} (Side Effect) Arthralgia
Arthralgia {u} (Side Effect) is caused by {v} (Compound) Benazepril
Benazepril {u} (Compound) resembles {v} (Compound) Quinapril
Mannitol {u} (Compound) causes {v} (Side Effect) Electrolyte imbalance
Electrolyte imbalance {u} (Side Effect) is caused by {v} (Compound) Dexamethasone
Dexamethasone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Quinapril
Mannitol {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Enalapril
Enalapril {u} (Compound) resembles {v} (Compound) Quinapril
Mannitol {u} (Compound) causes {v} (Side Effect) Electrolyte imbalance
Electrolyte imbalance {u} (Side Effect) is caused by {v} (Compound) Betamethasone
Betamethasone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Quinapril
Mannitol {u} (Compound) causes {v} (Side Effect) Infection
Infection {u} (Side Effect) is caused by {v} (Compound) Sodium bicarbonate
Sodium bicarbonate {u} may cause a minor interaction that can limit clinical effects when taken with {v} Quinapril
Mannitol {u} (Compound) causes {v} (Side Effect) Odynophagia
Odynophagia {u} (Side Effect) is caused by {v} (Compound) Potassium Iodide
Potassium Iodide {u} may lead to a major life threatening interaction when taken with {v} Quinapril
Mannitol (Compound) causes Skin disorder (Side Effect) and Skin disorder (Side Effect) is caused by Quinapril (Compound)
Mannitol (Compound) causes Skin disorder (Side Effect) and Skin disorder (Side Effect) is caused by Trandolapril (Compound) and Trandolapril (Compound) resembles Quinapril (Compound)
Mannitol (Compound) resembles Calcium glucoheptonate (Compound) and Calcium glucoheptonate (Compound) causes Diarrhoea (Side Effect) and Diarrhoea (Side Effect) is caused by Quinapril (Compound)
Mannitol (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Sirolimus (Compound) and Sirolimus may cause a moderate interaction that could exacerbate diseases when taken with Quinapril
Mannitol (Compound) causes Arthralgia (Side Effect) and Arthralgia (Side Effect) is caused by Benazepril (Compound) and Benazepril (Compound) resembles Quinapril (Compound)
Mannitol (Compound) causes Electrolyte imbalance (Side Effect) and Electrolyte imbalance (Side Effect) is caused by Dexamethasone (Compound) and Dexamethasone may cause a moderate interaction that could exacerbate diseases when taken with Quinapril
Mannitol (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Enalapril (Compound) and Enalapril (Compound) resembles Quinapril (Compound)
Mannitol (Compound) causes Electrolyte imbalance (Side Effect) and Electrolyte imbalance (Side Effect) is caused by Betamethasone (Compound) and Betamethasone may cause a moderate interaction that could exacerbate diseases when taken with Quinapril
Mannitol (Compound) causes Infection (Side Effect) and Infection (Side Effect) is caused by Sodium bicarbonate (Compound) and Sodium bicarbonate may cause a minor interaction that can limit clinical effects when taken with Quinapril
Mannitol (Compound) causes Odynophagia (Side Effect) and Odynophagia (Side Effect) is caused by Potassium Iodide (Compound) and Potassium Iodide may lead to a major life threatening interaction when taken with Quinapril