DDInter806 DDInter255
An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought about. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.
Ganciclovir {u} (Compound) downregulates {v} (Gene) GDF15
GDF15 {u} (Gene) is downregulated by {v} (Compound) Busulfan
Ganciclovir {u} (Compound) causes {v} (Side Effect) Dermatitis bullous
Dermatitis bullous {u} (Side Effect) is caused by {v} (Compound) Busulfan
Ganciclovir {u} (Compound) downregulates {v} (Gene) GDF15
GDF15 {u} (Gene) is regulated by {v} (Gene) MCOLN1
MCOLN1 {u} (Gene) is upregulated by {v} (Compound) Busulfan
Ganciclovir {u} (Compound) downregulates {v} (Gene) RPS4Y1
RPS4Y1 {u} (Gene) is regulated by {v} (Gene) MGST2
MGST2 {u} (Gene) is bound by {v} (Compound) Busulfan
Ganciclovir {u} (Compound) resembles {v} (Compound) Penciclovir
Penciclovir {u} (Compound) upregulates {v} (Gene) WRB
WRB {u} (Gene) is downregulated by {v} (Compound) Busulfan
Ganciclovir {u} (Compound) resembles {v} (Compound) Valaciclovir
Valaciclovir {u} (Compound) causes {v} (Side Effect) Stomatitis
Stomatitis {u} (Side Effect) is caused by {v} (Compound) Busulfan
Ganciclovir {u} (Compound) resembles {v} (Compound) Penciclovir
Penciclovir {u} (Compound) downregulates {v} (Gene) RPS4Y1
RPS4Y1 {u} (Gene) is downregulated by {v} (Compound) Busulfan
Ganciclovir {u} (Compound) resembles {v} (Compound) Acyclovir
Acyclovir {u} (Compound) upregulates {v} (Gene) TBXA2R
TBXA2R {u} (Gene) is upregulated by {v} (Compound) Busulfan
Ganciclovir {u} (Compound) resembles {v} (Compound) Valganciclovir
Valganciclovir {u} (Compound) causes {v} (Side Effect) Anorexia
Anorexia {u} (Side Effect) is caused by {v} (Compound) Busulfan
Ganciclovir {u} (Compound) binds {v} (Gene) SLC22A1
SLC22A1 {u} (Gene) is associated with {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is treated by {v} (Compound) Busulfan
Ganciclovir (Compound) downregulates GDF15 (Gene) and GDF15 (Gene) is downregulated by Busulfan (Compound)
Ganciclovir (Compound) causes Dermatitis bullous (Side Effect) and Dermatitis bullous (Side Effect) is caused by Busulfan (Compound)
Ganciclovir (Compound) downregulates GDF15 (Gene) and GDF15 (Gene) is regulated by MCOLN1 (Gene) and MCOLN1 (Gene) is upregulated by Busulfan (Compound)
Ganciclovir (Compound) downregulates RPS4Y1 (Gene) and RPS4Y1 (Gene) is regulated by MGST2 (Gene) and MGST2 (Gene) is bound by Busulfan (Compound)
Ganciclovir (Compound) resembles Penciclovir (Compound) and Penciclovir (Compound) upregulates WRB (Gene) and WRB (Gene) is downregulated by Busulfan (Compound)
Ganciclovir (Compound) resembles Valaciclovir (Compound) and Valaciclovir (Compound) causes Stomatitis (Side Effect) and Stomatitis (Side Effect) is caused by Busulfan (Compound)
Ganciclovir (Compound) resembles Penciclovir (Compound) and Penciclovir (Compound) downregulates RPS4Y1 (Gene) and RPS4Y1 (Gene) is downregulated by Busulfan (Compound)
Ganciclovir (Compound) resembles Acyclovir (Compound) and Acyclovir (Compound) upregulates TBXA2R (Gene) and TBXA2R (Gene) is upregulated by Busulfan (Compound)
Ganciclovir (Compound) resembles Valganciclovir (Compound) and Valganciclovir (Compound) causes Anorexia (Side Effect) and Anorexia (Side Effect) is caused by Busulfan (Compound)
Ganciclovir (Compound) binds SLC22A1 (Gene) and SLC22A1 (Gene) is associated with hematologic cancer (Disease) and hematologic cancer (Disease) is treated by Busulfan (Compound)