DDInter1662 DDInter645
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before beneficial effects are noticed. Sertraline displays enhanced safety or tolerability than other classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and other undesirable effects.[A1846,A187075,T28]
Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies. Enoxaparin markedly reduces the incidence of venous thromboembolism in hospitalized patients when compared to unfractionated [heparin], without increasing the risk of serious bleeding.[A228178,A228313]
Sertraline {u} (Compound) causes {v} (Side Effect) Oedema peripheral
Oedema peripheral {u} (Side Effect) is caused by {v} (Compound) Enoxaparin
Sertraline {u} (Compound) causes {v} (Side Effect) Oedema peripheral
Oedema peripheral {u} (Side Effect) is caused by {v} (Compound) Citalopram
Citalopram {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Enoxaparin
Sertraline {u} (Compound) downregulates {v} (Gene) TXNDC9
TXNDC9 {u} (Gene) is regulated by {v} (Gene) SERPINC1
SERPINC1 {u} (Gene) is bound by {v} (Compound) Enoxaparin
Sertraline {u} (Compound) upregulates {v} (Gene) FDPS
FDPS {u} (Gene) is regulated by {v} (Gene) SERPINC1
SERPINC1 {u} (Gene) is bound by {v} (Compound) Enoxaparin
Sertraline {u} (Compound) downregulates {v} (Gene) TXNDC9
TXNDC9 {u} (Gene) is downregulated by {v} (Compound) Sibutramine
Sibutramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Enoxaparin
Sertraline {u} (Compound) upregulates {v} (Gene) FDPS
FDPS {u} (Gene) is upregulated by {v} (Compound) Sunitinib
Sunitinib {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Enoxaparin
Sertraline {u} (Compound) downregulates {v} (Gene) TXNDC9
TXNDC9 {u} (Gene) is downregulated by {v} (Compound) Ketoprofen
Ketoprofen {u} may lead to a major life threatening interaction when taken with {v} Enoxaparin
Sertraline {u} (Compound) upregulates {v} (Gene) FDPS
FDPS {u} (Gene) is downregulated by {v} (Compound) Omacetaxine mepesuccinate
Omacetaxine mepesuccinate {u} may lead to a major life threatening interaction when taken with {v} Enoxaparin
Sertraline {u} (Compound) downregulates {v} (Gene) TXNDC9
TXNDC9 {u} (Gene) is downregulated by {v} (Compound) Dasatinib
Dasatinib {u} may lead to a major life threatening interaction when taken with {v} Enoxaparin
Sertraline {u} (Compound) causes {v} (Side Effect) Oedema peripheral
Oedema peripheral {u} (Side Effect) is caused by {v} (Compound) Milnacipran
Milnacipran {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Enoxaparin
Sertraline (Compound) causes Oedema peripheral (Side Effect) and Oedema peripheral (Side Effect) is caused by Enoxaparin (Compound)
Sertraline (Compound) causes Oedema peripheral (Side Effect) and Oedema peripheral (Side Effect) is caused by Citalopram (Compound) and Citalopram may cause a moderate interaction that could exacerbate diseases when taken with Enoxaparin
Sertraline (Compound) downregulates TXNDC9 (Gene) and TXNDC9 (Gene) is regulated by SERPINC1 (Gene) and SERPINC1 (Gene) is bound by Enoxaparin (Compound)
Sertraline (Compound) upregulates FDPS (Gene) and FDPS (Gene) is regulated by SERPINC1 (Gene) and SERPINC1 (Gene) is bound by Enoxaparin (Compound)
Sertraline (Compound) downregulates TXNDC9 (Gene) and TXNDC9 (Gene) is downregulated by Sibutramine (Compound) and Sibutramine may cause a moderate interaction that could exacerbate diseases when taken with Enoxaparin
Sertraline (Compound) upregulates FDPS (Gene) and FDPS (Gene) is upregulated by Sunitinib (Compound) and Sunitinib may cause a moderate interaction that could exacerbate diseases when taken with Enoxaparin
Sertraline (Compound) downregulates TXNDC9 (Gene) and TXNDC9 (Gene) is downregulated by Ketoprofen (Compound) and Ketoprofen may lead to a major life threatening interaction when taken with Enoxaparin
Sertraline (Compound) upregulates FDPS (Gene) and FDPS (Gene) is downregulated by Omacetaxine mepesuccinate (Compound) and Omacetaxine mepesuccinate may lead to a major life threatening interaction when taken with Enoxaparin
Sertraline (Compound) downregulates TXNDC9 (Gene) and TXNDC9 (Gene) is downregulated by Dasatinib (Compound) and Dasatinib may lead to a major life threatening interaction when taken with Enoxaparin
Sertraline (Compound) causes Oedema peripheral (Side Effect) and Oedema peripheral (Side Effect) is caused by Milnacipran (Compound) and Milnacipran may cause a moderate interaction that could exacerbate diseases when taken with Enoxaparin