DDInter381 DDInter688
Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe. It is used to treat hyperparathyroidism due to parathyroid tumours or renal failure.
Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on hemodialysis in February, 2017.
Cinacalcet {u} (Compound) palliates {v} (Disease) chronic kidney failure
chronic kidney failure {u} (Disease) is palliated by {v} (Compound) Torasemide
Torasemide {u} may lead to a major life threatening interaction when taken with {v} Etelcalcetide
Cinacalcet {u} (Compound) causes {v} (Side Effect) Rash
Rash {u} (Side Effect) is caused by {v} (Compound) Torasemide
Torasemide {u} may lead to a major life threatening interaction when taken with {v} Etelcalcetide
Cinacalcet {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Pentamidine
Pentamidine {u} may lead to a major life threatening interaction when taken with {v} Etelcalcetide
Cinacalcet {u} (Compound) resembles {v} (Compound) Fluoxetine
Fluoxetine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pentamidine
Pentamidine {u} may lead to a major life threatening interaction when taken with {v} Etelcalcetide
Cinacalcet (Compound) palliates chronic kidney failure (Disease) and chronic kidney failure (Disease) is palliated by Torasemide (Compound) and Torasemide may lead to a major life threatening interaction when taken with Etelcalcetide
Cinacalcet (Compound) causes Rash (Side Effect) and Rash (Side Effect) is caused by Torasemide (Compound) and Torasemide may lead to a major life threatening interaction when taken with Etelcalcetide
Cinacalcet (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Pentamidine (Compound) and Pentamidine may lead to a major life threatening interaction when taken with Etelcalcetide
Cinacalcet (Compound) resembles Fluoxetine (Compound) and Fluoxetine may cause a moderate interaction that could exacerbate diseases when taken with Pentamidine and Pentamidine may lead to a major life threatening interaction when taken with Etelcalcetide