DDInter1710 DDInter576
A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.
Stavudine {u} (Compound) upregulates {v} (Gene) PAK1
PAK1 {u} (Gene) is upregulated by {v} (Compound) Disulfiram
Stavudine {u} (Compound) downregulates {v} (Gene) PIN1
PIN1 {u} (Gene) is downregulated by {v} (Compound) Disulfiram
Stavudine {u} (Compound) causes {v} (Side Effect) Neuropathy
Neuropathy {u} (Side Effect) is caused by {v} (Compound) Disulfiram
Stavudine {u} (Compound) upregulates {v} (Gene) PAK1
PAK1 {u} (Gene) is regulated by {v} (Gene) FHL2
FHL2 {u} (Gene) is upregulated by {v} (Compound) Disulfiram
Stavudine {u} (Compound) upregulates {v} (Gene) MAL
MAL {u} (Gene) is regulated by {v} (Gene) CYP2E1
CYP2E1 {u} (Gene) is bound by {v} (Compound) Disulfiram
Stavudine {u} (Compound) downregulates {v} (Gene) PIN1
PIN1 {u} (Gene) regulates {v} (Gene) FHL2
FHL2 {u} (Gene) is upregulated by {v} (Compound) Disulfiram
Stavudine {u} (Compound) resembles {v} (Compound) Telbivudine
Telbivudine {u} (Compound) causes {v} (Side Effect) Neuropathy peripheral
Neuropathy peripheral {u} (Side Effect) is caused by {v} (Compound) Disulfiram
Stavudine {u} (Compound) downregulates {v} (Gene) PIN1
PIN1 {u} (Gene) is regulated by {v} (Gene) IL11
IL11 {u} (Gene) is upregulated by {v} (Compound) Disulfiram
Stavudine {u} (Compound) downregulates {v} (Gene) CDKN1B
CDKN1B {u} (Gene) interacts with {v} (Gene) MYC
MYC {u} (Gene) is upregulated by {v} (Compound) Disulfiram
Stavudine {u} (Compound) resembles {v} (Compound) Idoxuridine
Idoxuridine {u} (Compound) downregulates {v} (Gene) CD320
CD320 {u} (Gene) is downregulated by {v} (Compound) Disulfiram
Stavudine (Compound) upregulates PAK1 (Gene) and PAK1 (Gene) is upregulated by Disulfiram (Compound)
Stavudine (Compound) downregulates PIN1 (Gene) and PIN1 (Gene) is downregulated by Disulfiram (Compound)
Stavudine (Compound) causes Neuropathy (Side Effect) and Neuropathy (Side Effect) is caused by Disulfiram (Compound)
Stavudine (Compound) upregulates PAK1 (Gene) and PAK1 (Gene) is regulated by FHL2 (Gene) and FHL2 (Gene) is upregulated by Disulfiram (Compound)
Stavudine (Compound) upregulates MAL (Gene) and MAL (Gene) is regulated by CYP2E1 (Gene) and CYP2E1 (Gene) is bound by Disulfiram (Compound)
Stavudine (Compound) downregulates PIN1 (Gene) and PIN1 (Gene) regulates FHL2 (Gene) and FHL2 (Gene) is upregulated by Disulfiram (Compound)
Stavudine (Compound) resembles Telbivudine (Compound) and Telbivudine (Compound) causes Neuropathy peripheral (Side Effect) and Neuropathy peripheral (Side Effect) is caused by Disulfiram (Compound)
Stavudine (Compound) downregulates PIN1 (Gene) and PIN1 (Gene) is regulated by IL11 (Gene) and IL11 (Gene) is upregulated by Disulfiram (Compound)
Stavudine (Compound) downregulates CDKN1B (Gene) and CDKN1B (Gene) interacts with MYC (Gene) and MYC (Gene) is upregulated by Disulfiram (Compound)
Stavudine (Compound) resembles Idoxuridine (Compound) and Idoxuridine (Compound) downregulates CD320 (Gene) and CD320 (Gene) is downregulated by Disulfiram (Compound)