DDInter856 DDInter324
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated hepar
A semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative microorganisms.
Cefotetan {u} (Compound) resembles {v} (Compound) Latamoxef
Cefotetan {u} (Compound) resembles {v} (Compound) Cefpiramide
Cefotetan {u} (Compound) binds {v} (Gene) ALB
Cefotetan {u} (Compound) is included by {v} (Pharmacologic Class) Cephalosporins
Cefotetan {u} (Compound) causes {v} (Side Effect) Nephropathy toxic
Cefotetan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Gentamicin
Cefotetan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Picosulfuric acid
Cefotetan (Compound) resembles Latamoxef (Compound)
Cefotetan (Compound) resembles Cefpiramide (Compound)
Cefotetan (Compound) binds ALB (Gene)
Cefotetan (Compound) is included by Cephalosporins (Pharmacologic Class)
Cefotetan (Compound) causes Nephropathy toxic (Side Effect)
Cefotetan may cause a moderate interaction that could exacerbate diseases when taken with Gentamicin
Cefotetan may cause a moderate interaction that could exacerbate diseases when taken with Picosulfuric acid