DDInter1066 DDInter1860
Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication. In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local anesthesia for a large variety of surgical procedures [F4349, L5930, L5948]. It ultimately elicits its numbing activity by blocking sodium channels so that the neurons of local tissues that have the medication applied on are transiently incapable of signaling the brain regarding sensations [F4349, L5930, L5948]. In doing so, however, it can block or decrease muscle contractile, resulting in effects like vasodilation, hypotension, and irregular heart rate, among others [F4349, L5930, L5948]. As a result, lidocaine is also considered a class Ib anti-arrhythmic agent [L
Withdrawn in the United Kingdom due to risk of psychiatric adverse drug reactions. This drug continues to be available in the U.S. Internationally, triazolam is a Schedule IV drug under the Convention on Psychotropic Substances.
Lidocaine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Halazepam
Halazepam {u} (Compound) resembles {v} (Compound) Triazolam
Lidocaine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lorazepam
Lorazepam {u} (Compound) resembles {v} (Compound) Triazolam
Lidocaine {u} (Compound) binds {v} (Gene) CYP3A5
CYP3A5 {u} (Gene) is bound by {v} (Compound) Triazolam
Lidocaine {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Triazolam
Lidocaine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Halazepam
Halazepam {u} (Compound) resembles {v} (Compound) Camazepam
Camazepam {u} (Compound) resembles {v} (Compound) Triazolam
Lidocaine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Quazepam
Quazepam {u} (Compound) resembles {v} (Compound) Flunitrazepam
Flunitrazepam {u} (Compound) resembles {v} (Compound) Triazolam
Lidocaine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lorazepam
Lorazepam {u} (Compound) resembles {v} (Compound) Camazepam
Camazepam {u} (Compound) resembles {v} (Compound) Triazolam
Lidocaine {u} (Compound) binds {v} (Gene) CYP3A5
CYP3A5 {u} (Gene) is bound by {v} (Compound) Midazolam
Midazolam {u} (Compound) resembles {v} (Compound) Triazolam
Lidocaine {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Flunitrazepam
Flunitrazepam {u} (Compound) resembles {v} (Compound) Triazolam
Lidocaine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Temazepam
Temazepam {u} (Compound) resembles {v} (Compound) Flunitrazepam
Flunitrazepam {u} (Compound) resembles {v} (Compound) Triazolam
Lidocaine may cause a moderate interaction that could exacerbate diseases when taken with Halazepam and Halazepam (Compound) resembles Triazolam (Compound)
Lidocaine may cause a moderate interaction that could exacerbate diseases when taken with Lorazepam and Lorazepam (Compound) resembles Triazolam (Compound)
Lidocaine (Compound) binds CYP3A5 (Gene) and CYP3A5 (Gene) is bound by Triazolam (Compound)
Lidocaine (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Triazolam (Compound)
Lidocaine may cause a moderate interaction that could exacerbate diseases when taken with Halazepam and Halazepam (Compound) resembles Camazepam (Compound) and Camazepam (Compound) resembles Triazolam (Compound)
Lidocaine may cause a moderate interaction that could exacerbate diseases when taken with Quazepam and Quazepam (Compound) resembles Flunitrazepam (Compound) and Flunitrazepam (Compound) resembles Triazolam (Compound)
Lidocaine may cause a moderate interaction that could exacerbate diseases when taken with Lorazepam and Lorazepam (Compound) resembles Camazepam (Compound) and Camazepam (Compound) resembles Triazolam (Compound)
Lidocaine (Compound) binds CYP3A5 (Gene) and CYP3A5 (Gene) is bound by Midazolam (Compound) and Midazolam (Compound) resembles Triazolam (Compound)
Lidocaine (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Flunitrazepam (Compound) and Flunitrazepam (Compound) resembles Triazolam (Compound)
Lidocaine may cause a moderate interaction that could exacerbate diseases when taken with Temazepam and Temazepam (Compound) resembles Flunitrazepam (Compound) and Flunitrazepam (Compound) resembles Triazolam (Compound)