DDInter416 DDInter1187
This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s. Clotrimazole falls under the _imidazole_ category of _azole_ antifungals, possessing broad-spectrum antimycotic activity. It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers. The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain widespread acceptance for the treatment of mycotic outbreaks such as vaginal yeast infections as well as athlete's foot.
A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)
Clotrimazole {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Methylergometrine
Clotrimazole {u} (Compound) causes {v} (Side Effect) Vomiting
Vomiting {u} (Side Effect) is caused by {v} (Compound) Methylergometrine
Clotrimazole {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Pergolide
Pergolide {u} (Compound) resembles {v} (Compound) Methylergometrine
Clotrimazole {u} (Compound) causes {v} (Side Effect) Vomiting
Vomiting {u} (Side Effect) is caused by {v} (Compound) Pergolide
Pergolide {u} (Compound) resembles {v} (Compound) Methylergometrine
Clotrimazole {u} (Compound) causes {v} (Side Effect) Muscle spasms
Muscle spasms {u} (Side Effect) is caused by {v} (Compound) Ergometrine
Ergometrine {u} (Compound) resembles {v} (Compound) Methylergometrine
Clotrimazole {u} (Compound) resembles {v} (Compound) Methadone
Methadone {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Methylergometrine
Clotrimazole {u} (Compound) resembles {v} (Compound) Diphenoxylate
Diphenoxylate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pergolide
Pergolide {u} (Compound) resembles {v} (Compound) Methylergometrine
Clotrimazole {u} (Compound) resembles {v} (Compound) Methadone
Methadone {u} (Compound) causes {v} (Side Effect) Anaphylactic shock
Anaphylactic shock {u} (Side Effect) is caused by {v} (Compound) Methylergometrine
Clotrimazole {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Ergometrine
Ergometrine {u} (Compound) resembles {v} (Compound) Methylergometrine
Clotrimazole {u} (Compound) causes {v} (Side Effect) Muscle spasms
Muscle spasms {u} (Side Effect) is caused by {v} (Compound) Sirolimus
Sirolimus {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methylergometrine
Clotrimazole (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Methylergometrine (Compound)
Clotrimazole (Compound) causes Vomiting (Side Effect) and Vomiting (Side Effect) is caused by Methylergometrine (Compound)
Clotrimazole (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Pergolide (Compound) and Pergolide (Compound) resembles Methylergometrine (Compound)
Clotrimazole (Compound) causes Vomiting (Side Effect) and Vomiting (Side Effect) is caused by Pergolide (Compound) and Pergolide (Compound) resembles Methylergometrine (Compound)
Clotrimazole (Compound) causes Muscle spasms (Side Effect) and Muscle spasms (Side Effect) is caused by Ergometrine (Compound) and Ergometrine (Compound) resembles Methylergometrine (Compound)
Clotrimazole (Compound) resembles Methadone (Compound) and Methadone (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Methylergometrine (Compound)
Clotrimazole (Compound) resembles Diphenoxylate (Compound) and Diphenoxylate may cause a moderate interaction that could exacerbate diseases when taken with Pergolide and Pergolide (Compound) resembles Methylergometrine (Compound)
Clotrimazole (Compound) resembles Methadone (Compound) and Methadone (Compound) causes Anaphylactic shock (Side Effect) and Anaphylactic shock (Side Effect) is caused by Methylergometrine (Compound)
Clotrimazole (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Ergometrine (Compound) and Ergometrine (Compound) resembles Methylergometrine (Compound)
Clotrimazole (Compound) causes Muscle spasms (Side Effect) and Muscle spasms (Side Effect) is caused by Sirolimus (Compound) and Sirolimus may cause a moderate interaction that could exacerbate diseases when taken with Methylergometrine