DDInter1429 DDInter1016
Perflutren, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of lipid-coated microspheres filled with octafluoropropane(OFP) gas. When exposed to ultrasound waves, the microspheres resonate and "echo" strong signals back to the ultrasound machine. The difference in density between the gas-filled bubbles and the blood around them creates an increased level of contrast visible in the resulting ultrasound image. During echocardiography, activated Perflutren enhances images of the inner edges or borders of the heart, producing an improved image that may enable physicians to better diagnose patients.
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose]. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. [sucrose]). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in patients with cirrhosis.[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.
Perflutren {u} (Compound) resembles {v} (Compound) Sevoflurane
Perflutren {u} (Compound) is included by {v} (Pharmacologic Class) Ultrasound Contrast Activity
Perflutren {u} (Compound) causes {v} (Side Effect) Haemoglobin
Perflutren {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metronidazole
Perflutren {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lactulose
Perflutren {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mefloquine
Perflutren {u} may lead to a major life threatening interaction when taken with {v} Cabozantinib
Perflutren {u} may lead to a major life threatening interaction when taken with {v} Anagrelide
Perflutren (Compound) resembles Sevoflurane (Compound)
Perflutren (Compound) is included by Ultrasound Contrast Activity (Pharmacologic Class)
Perflutren (Compound) causes Haemoglobin (Side Effect)
Perflutren may cause a minor interaction that can limit clinical effects when taken with Metronidazole
Perflutren may cause a moderate interaction that could exacerbate diseases when taken with Lactulose
Perflutren may cause a moderate interaction that could exacerbate diseases when taken with Mefloquine
Perflutren may lead to a major life threatening interaction when taken with Cabozantinib
Perflutren may lead to a major life threatening interaction when taken with Anagrelide