DDInter1793 DDInter1747
A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. This piperazine phenothiazine does not prevent vertigo or motion sickness. (From AMA Drug Evaluations Annual, 1994, p457)
Tasimelteon is a selective dual melatonin receptor agonist indicated for the treatment of Non-24-Hour Sleep-Wake Disorder (N24HSWD). Occurring commonly in blind individuals without light perception, this condition is often characterized by periods of night-time insomnia and day-time sleepiness. In blind individuals, a lack of light stimulation causes an extension of the 24-hour circadian cycle and can lead to progressively delayed sleep onset. By activating melatonin receptors MT1 and MT2 in the suprachiasmatic nucleus of the brain, tasimelteon has been shown to improve sleep by resynchronizing the circadian rhythm through its "non-photic" mechanism. Tasimelteon is currently the only drug available for the treatment of N24HSWD and was granted orphan drug status by the FDA in 2010.
Thiethylperazine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium carbonate
Thiethylperazine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Sucralfate
Thiethylperazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sotalol
Thiethylperazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pregabalin
Thiethylperazine {u} may lead to a major life threatening interaction when taken with {v} Iohexol
Thiethylperazine {u} may lead to a major life threatening interaction when taken with {v} Tramadol
Thiethylperazine may cause a minor interaction that can limit clinical effects when taken with Magnesium carbonate
Thiethylperazine may cause a minor interaction that can limit clinical effects when taken with Sucralfate
Thiethylperazine may cause a moderate interaction that could exacerbate diseases when taken with Sotalol
Thiethylperazine may cause a moderate interaction that could exacerbate diseases when taken with Pregabalin
Thiethylperazine may lead to a major life threatening interaction when taken with Iohexol
Thiethylperazine may lead to a major life threatening interaction when taken with Tramadol