DDInter1831 DDInter856
A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated heparin is more specific than LMWH for thrombin. Furthermore, the effects of UH can typically be reversed by using protamine sulfate.
Tolmetin {u} (Compound) resembles {v} (Compound) Zolpidem
Tolmetin {u} (Compound) resembles {v} (Compound) Lumiracoxib
Tolmetin {u} (Compound) binds {v} (Gene) SLC22A6
Tolmetin {u} (Compound) upregulates {v} (Gene) MAL
Tolmetin {u} (Compound) palliates {v} (Disease) osteoarthritis
Tolmetin {u} (Compound) is included by {v} (Pharmacologic Class) Nonsteroidal Anti-inflammatory Compounds
Tolmetin {u} (Compound) downregulates {v} (Gene) IARS2
Tolmetin {u} (Compound) causes {v} (Side Effect) Glossitis
Tolmetin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Famotidine
Tolmetin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Abciximab
Tolmetin (Compound) resembles Zolpidem (Compound)
Tolmetin (Compound) resembles Lumiracoxib (Compound)
Tolmetin (Compound) binds SLC22A6 (Gene)
Tolmetin (Compound) upregulates MAL (Gene)
Tolmetin (Compound) palliates osteoarthritis (Disease)
Tolmetin (Compound) is included by Nonsteroidal Anti-inflammatory Compounds (Pharmacologic Class)
Tolmetin (Compound) downregulates IARS2 (Gene)
Tolmetin (Compound) causes Glossitis (Side Effect)
Tolmetin may cause a minor interaction that can limit clinical effects when taken with Famotidine
Tolmetin may cause a moderate interaction that could exacerbate diseases when taken with Abciximab