DDInter1948 DDInter105
Vortioxetine is an antidepressant medication indicated for the treatment of major depressive disorder (MDD). It is classified as a serotonin modulator and stimulator (SMS) as it has a multimodal mechanism of action towards the serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin receptors and inhibits the reuptake of serotonin. More specifically, vortioxetine acts via the following biological mechanisms: as a serotonin reuptake inhibitor (SRI) through inhibition of the serotonin transporter, as a partial agonist of the 5-HT1B receptor, an agonist of 5-HT1A, and an antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors. SMSs were developed because there are many different subtypes of serotonin receptors, however, not all of these receptors appear to be involved in the antidepressant effects of SRIs. Some serotonin receptors seem to play a relatively neutral or insignificant role in the regulation
A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Vortioxetine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Elagolix
Vortioxetine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Anistreplase
Vortioxetine {u} may lead to a major life threatening interaction when taken with {v} Doxepin
Vortioxetine {u} may lead to a major life threatening interaction when taken with {v} Dacomitinib
Vortioxetine may cause a moderate interaction that could exacerbate diseases when taken with Elagolix
Vortioxetine may cause a moderate interaction that could exacerbate diseases when taken with Anistreplase
Vortioxetine may lead to a major life threatening interaction when taken with Doxepin
Vortioxetine may lead to a major life threatening interaction when taken with Dacomitinib