DDInter1230 DDInter832
Mirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994. This drug was first manufactured by Organon Inc., and received FDA approval in 1997 for the treatment of major depressive disorder.[T595, L6157] The effects of this drug may be observed as early as 1 week after beginning therapy.[A178144,L6160] In addition to its beneficial effects in depression, mirtazapine has been reported to be efficacious in the off-label management of various other conditions. It may improve the symptoms of neurological disorders, reverse weight loss caused by medical conditions, improve sleep, and prevent nausea and vomiting after surgery.
A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Mirtazapine {u} (Compound) resembles {v} (Compound) Mianserin
Mirtazapine {u} (Compound) resembles {v} (Compound) Chlorcyclizine
Mirtazapine {u} (Compound) binds {v} (Gene) HTR2C
Mirtazapine {u} (Compound) upregulates {v} (Gene) AGR2
Mirtazapine {u} (Compound) downregulates {v} (Gene) KIF20A
Mirtazapine {u} (Compound) causes {v} (Side Effect) Cardiomegaly
Mirtazapine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metronidazole
Mirtazapine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lapatinib
Mirtazapine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mefloquine
Mirtazapine {u} may lead to a major life threatening interaction when taken with {v} Bupropion
Mirtazapine (Compound) resembles Mianserin (Compound)
Mirtazapine (Compound) resembles Chlorcyclizine (Compound)
Mirtazapine (Compound) binds HTR2C (Gene)
Mirtazapine (Compound) upregulates AGR2 (Gene)
Mirtazapine (Compound) downregulates KIF20A (Gene)
Mirtazapine (Compound) causes Cardiomegaly (Side Effect)
Mirtazapine may cause a minor interaction that can limit clinical effects when taken with Metronidazole
Mirtazapine may cause a moderate interaction that could exacerbate diseases when taken with Lapatinib
Mirtazapine may cause a moderate interaction that could exacerbate diseases when taken with Mefloquine
Mirtazapine may lead to a major life threatening interaction when taken with Bupropion