DDInter1646 DDInter119
Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.
Armodafinil is the enantiopure of the wakefulness-promoting agent modafinil (Provigil), and is indicated to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea (OSA), narcolepsy, or shift work disorder (SWD). Research has shown that armodafinil significantly improves driving simulator performance in patients with SWD. Armodafinil consists of the (−)-R-enantiomer of the racemic modafinil. Armodafinil is produced by the pharmaceutical company Cephalon Inc. (a wholly owned subsidiary of Teva Pharmaceutical Industries Ltd.) and was approved by the U.S. Food and Drug Administration (FDA) in June 2007.
Saxagliptin {u} (Compound) resembles {v} (Compound) Vildagliptin
Saxagliptin {u} (Compound) binds {v} (Gene) DPP8
Saxagliptin {u} (Compound) causes {v} (Side Effect) Upper respiratory tract infection
Saxagliptin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Modafinil
Saxagliptin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Midostaurin
Saxagliptin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Hydroflumethiazide
Saxagliptin {u} may lead to a major life threatening interaction when taken with {v} Bexarotene
Saxagliptin (Compound) resembles Vildagliptin (Compound)
Saxagliptin (Compound) binds DPP8 (Gene)
Saxagliptin (Compound) causes Upper respiratory tract infection (Side Effect)
Saxagliptin may cause a minor interaction that can limit clinical effects when taken with Modafinil
Saxagliptin may cause a moderate interaction that could exacerbate diseases when taken with Midostaurin
Saxagliptin may cause a moderate interaction that could exacerbate diseases when taken with Hydroflumethiazide
Saxagliptin may lead to a major life threatening interaction when taken with Bexarotene