DDInter522 DDInter1625
An antimitotic agent with immunosuppressive properties. Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex. [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy.
Rubella virus vaccine is a live attenuated virus vaccine for active immunization against rubella (German measles) that is subcutaneously administered. It is prepared from RA 27/3 strain of live attenuated rubella virus. Rubella is a common childhood disease, caused by rubella virus (togavirus).
Dexrazoxane {u} (Compound) binds {v} (Gene) TOP2B
Dexrazoxane {u} (Compound) upregulates {v} (Gene) CNOT4
Dexrazoxane {u} (Compound) downregulates {v} (Gene) PCNA
Dexrazoxane {u} (Compound) causes {v} (Side Effect) Febrile neutropenia
Dexrazoxane {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Human adenovirus e serotype 4 strain cl-68578 antigen
Dexrazoxane {u} may lead to a major life threatening interaction when taken with {v} Measles virus vaccine live attenuated
Dexrazoxane (Compound) binds TOP2B (Gene)
Dexrazoxane (Compound) upregulates CNOT4 (Gene)
Dexrazoxane (Compound) downregulates PCNA (Gene)
Dexrazoxane (Compound) causes Febrile neutropenia (Side Effect)
Dexrazoxane may cause a moderate interaction that could exacerbate diseases when taken with Human adenovirus e serotype 4 strain cl-68578 antigen
Dexrazoxane may lead to a major life threatening interaction when taken with Measles virus vaccine live attenuated