DDInter1811 DDInter1956
A nitroimidazole antitrichomonal agent effective against _Trichomonas vaginalis_, _Entamoeba histolytica_, and _Giardia lamblia_ infections.
A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the elongation of DNA chains, thus resulting in the termination of viral DNA growth. The compound is a potent inhibitor of HIV replication at low concentrations, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Its principal toxic side effect is axonal degeneration resulting in peripheral neuropathy.
Tinidazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Didanosine
Didanosine {u} (Compound) resembles {v} (Compound) Zalcitabine
Tinidazole {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Zalcitabine
Tinidazole {u} (Compound) downregulates {v} (Gene) GDF15
GDF15 {u} (Gene) is downregulated by {v} (Compound) Zalcitabine
Tinidazole {u} (Compound) causes {v} (Side Effect) Decreased appetite
Decreased appetite {u} (Side Effect) is caused by {v} (Compound) Zalcitabine
Tinidazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Didanosine
Didanosine {u} (Compound) binds {v} (Gene) SLC22A6
SLC22A6 {u} (Gene) is bound by {v} (Compound) Zalcitabine
Tinidazole {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Cytarabine
Cytarabine {u} (Compound) resembles {v} (Compound) Zalcitabine
Tinidazole {u} (Compound) downregulates {v} (Gene) GDF15
GDF15 {u} (Gene) is regulated by {v} (Gene) DCK
DCK {u} (Gene) is bound by {v} (Compound) Zalcitabine
Tinidazole {u} (Compound) causes {v} (Side Effect) Decreased appetite
Decreased appetite {u} (Side Effect) is caused by {v} (Compound) Gemcitabine
Gemcitabine {u} (Compound) resembles {v} (Compound) Zalcitabine
Tinidazole {u} (Compound) causes {v} (Side Effect) Candida infection
Candida infection {u} (Side Effect) is caused by {v} (Compound) Decitabine
Decitabine {u} (Compound) resembles {v} (Compound) Zalcitabine
Tinidazole {u} (Compound) resembles {v} (Compound) Metronidazole
Metronidazole {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Zalcitabine
Tinidazole may cause a moderate interaction that could exacerbate diseases when taken with Didanosine and Didanosine (Compound) resembles Zalcitabine (Compound)
Tinidazole (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Zalcitabine (Compound)
Tinidazole (Compound) downregulates GDF15 (Gene) and GDF15 (Gene) is downregulated by Zalcitabine (Compound)
Tinidazole (Compound) causes Decreased appetite (Side Effect) and Decreased appetite (Side Effect) is caused by Zalcitabine (Compound)
Tinidazole may cause a moderate interaction that could exacerbate diseases when taken with Didanosine and Didanosine (Compound) binds SLC22A6 (Gene) and SLC22A6 (Gene) is bound by Zalcitabine (Compound)
Tinidazole (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Cytarabine (Compound) and Cytarabine (Compound) resembles Zalcitabine (Compound)
Tinidazole (Compound) downregulates GDF15 (Gene) and GDF15 (Gene) is regulated by DCK (Gene) and DCK (Gene) is bound by Zalcitabine (Compound)
Tinidazole (Compound) causes Decreased appetite (Side Effect) and Decreased appetite (Side Effect) is caused by Gemcitabine (Compound) and Gemcitabine (Compound) resembles Zalcitabine (Compound)
Tinidazole (Compound) causes Candida infection (Side Effect) and Candida infection (Side Effect) is caused by Decitabine (Compound) and Decitabine (Compound) resembles Zalcitabine (Compound)
Tinidazole (Compound) resembles Metronidazole (Compound) and Metronidazole (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Zalcitabine (Compound)