DDInter297 DDInter536
Carbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. The product label for carbinoxamine as an over the counter cough and cold medicine is being modified to state "do not use" in children under 4 years of age in order to prevent and reduce misuse, as many unapproved carbinoxamine-containing preparations contained inappropriate labeling, which promoted unapproved uses (including management of congestion, cough, the common cold, and the use in children under 2 years of age), which can potentially cause serious health risks.
Dichloralphenazone is a sedative composed of chloral hydrate and phenazone. It is typically found in combination products Nodolor and Midrin containing [isometheptene] and [acetaminophen] used for the relief of tension and vascular headaches. It is a US Schedule IV drug and its clinical use is limited.
Carbinoxamine {u} (Compound) resembles {v} (Compound) Bisacodyl
Carbinoxamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Doxylamine
Carbinoxamine {u} (Compound) binds {v} (Gene) CYP2C9
Carbinoxamine {u} (Compound) upregulates {v} (Gene) CDK6
Carbinoxamine {u} (Compound) is included by {v} (Pharmacologic Class) Histamine H1 Receptor Antagonists
Carbinoxamine {u} (Compound) downregulates {v} (Gene) CTNND1
Carbinoxamine {u} (Compound) causes {v} (Side Effect) Dizziness
Carbinoxamine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Hyaluronidase
Carbinoxamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Aclidinium
Carbinoxamine {u} may lead to a major life threatening interaction when taken with {v} Dextropropoxyphene
Carbinoxamine (Compound) resembles Bisacodyl (Compound)
Carbinoxamine may cause a moderate interaction that could exacerbate diseases when taken with Doxylamine
Carbinoxamine (Compound) binds CYP2C9 (Gene)
Carbinoxamine (Compound) upregulates CDK6 (Gene)
Carbinoxamine (Compound) is included by Histamine H1 Receptor Antagonists (Pharmacologic Class)
Carbinoxamine (Compound) downregulates CTNND1 (Gene)
Carbinoxamine (Compound) causes Dizziness (Side Effect)
Carbinoxamine may cause a minor interaction that can limit clinical effects when taken with Hyaluronidase
Carbinoxamine may cause a moderate interaction that could exacerbate diseases when taken with Aclidinium
Carbinoxamine may lead to a major life threatening interaction when taken with Dextropropoxyphene