DDInter1200 DDInter278
Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US. Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.
Calcium lactate is a salt that consists of two lactate anions for each calcium cation (Ca2+). It is prepared commercially by the neutralization of lactic acid with calcium carbonate or calcium hydroxide. Approved by the FDA as a direct food substance affirmed as generally recognized as safe, calcium lactate is used as a firming agent, flavoring agent, leavening agent, stabilizer, and thickener . Calcium lactate is also found in daily dietary supplements as a source of calcium. It is also available in various hydrate forms, where calcium lactate pentahydrate is the most common.
Metoprolol {u} (Compound) resembles {v} (Compound) Oxprenolol
Metoprolol {u} (Compound) resembles {v} (Compound) Metipranolol
Metoprolol {u} (Compound) treats {v} (Disease) hypertension
Metoprolol {u} (Compound) binds {v} (Gene) SLC22A2
Metoprolol {u} (Compound) upregulates {v} (Gene) HOOK2
Metoprolol {u} (Compound) downregulates {v} (Gene) LAP3
Metoprolol {u} (Compound) causes {v} (Side Effect) Coma
Metoprolol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Levothyroxine
Metoprolol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Glucagon
Metoprolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pasireotide
Metoprolol (Compound) resembles Oxprenolol (Compound)
Metoprolol (Compound) resembles Metipranolol (Compound)
Metoprolol (Compound) treats hypertension (Disease)
Metoprolol (Compound) binds SLC22A2 (Gene)
Metoprolol (Compound) upregulates HOOK2 (Gene)
Metoprolol (Compound) downregulates LAP3 (Gene)
Metoprolol (Compound) causes Coma (Side Effect)
Metoprolol may cause a minor interaction that can limit clinical effects when taken with Levothyroxine
Metoprolol may cause a minor interaction that can limit clinical effects when taken with Glucagon
Metoprolol may cause a moderate interaction that could exacerbate diseases when taken with Pasireotide