DDInter915 DDInter985
Indacaterol is a novel, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist developed for Novartis for the once-daily management of asthma and chronic obstructive pulmonary disease. It was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011. It is marketed in Europe as Onbrez and in America as Arcapta Neohaler. Indacaterol is provided as its maleate salt form. Indacaterol is also a chiral molecule but only the pure R-enantiomer is dispensed.
Isometheptene is a sympathomimetic drug that causes vasoconstriction. It is used for treating migraines and tension headaches.
Indacaterol {u} (Compound) resembles {v} (Compound) Procaterol
Procaterol {u} (Compound) downregulates {v} (Gene) ATG3
ATG3 {u} (Gene) is upregulated by {v} (Compound) Isometheptene
Indacaterol {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) regulates {v} (Gene) ST6GALNAC2
ST6GALNAC2 {u} (Gene) is upregulated by {v} (Compound) Isometheptene
Indacaterol {u} (Compound) resembles {v} (Compound) Procaterol
Procaterol {u} (Compound) upregulates {v} (Gene) PAK1
PAK1 {u} (Gene) is upregulated by {v} (Compound) Isometheptene
Indacaterol {u} (Compound) treats {v} (Disease) asthma
asthma {u} (Disease) is treated by {v} (Compound) Formoterol
Formoterol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Isometheptene
Indacaterol {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Reserpine
Reserpine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Isometheptene
Indacaterol {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Levomilnacipran
Levomilnacipran {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Isometheptene
Indacaterol {u} (Compound) is included by {v} (Pharmacologic Class) Adrenergic beta2-Agonists
Adrenergic beta2-Agonists {u} (Pharmacologic Class) includes {v} (Compound) Salbutamol
Salbutamol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Isometheptene
Indacaterol {u} (Compound) causes {v} (Side Effect) Cardiac disorder
Cardiac disorder {u} (Side Effect) is caused by {v} (Compound) Dexmethylphenidate
Dexmethylphenidate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Isometheptene
Indacaterol {u} (Compound) causes {v} (Side Effect) Atrial fibrillation
Atrial fibrillation {u} (Side Effect) is caused by {v} (Compound) Selegiline
Selegiline {u} may lead to a major life threatening interaction when taken with {v} Isometheptene
Indacaterol {u} (Compound) binds {v} (Gene) ADRB1
ADRB1 {u} (Gene) is bound by {v} (Compound) Bromocriptine
Bromocriptine {u} may lead to a major life threatening interaction when taken with {v} Isometheptene
Indacaterol (Compound) resembles Procaterol (Compound) and Procaterol (Compound) downregulates ATG3 (Gene) and ATG3 (Gene) is upregulated by Isometheptene (Compound)
Indacaterol (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) regulates ST6GALNAC2 (Gene) and ST6GALNAC2 (Gene) is upregulated by Isometheptene (Compound)
Indacaterol (Compound) resembles Procaterol (Compound) and Procaterol (Compound) upregulates PAK1 (Gene) and PAK1 (Gene) is upregulated by Isometheptene (Compound)
Indacaterol (Compound) treats asthma (Disease) and asthma (Disease) is treated by Formoterol (Compound) and Formoterol may cause a moderate interaction that could exacerbate diseases when taken with Isometheptene
Indacaterol (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Reserpine (Compound) and Reserpine may cause a moderate interaction that could exacerbate diseases when taken with Isometheptene
Indacaterol (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Levomilnacipran (Compound) and Levomilnacipran may cause a moderate interaction that could exacerbate diseases when taken with Isometheptene
Indacaterol (Compound) is included by Adrenergic beta2-Agonists (Pharmacologic Class) and Adrenergic beta2-Agonists (Pharmacologic Class) includes Salbutamol (Compound) and Salbutamol may cause a moderate interaction that could exacerbate diseases when taken with Isometheptene
Indacaterol (Compound) causes Cardiac disorder (Side Effect) and Cardiac disorder (Side Effect) is caused by Dexmethylphenidate (Compound) and Dexmethylphenidate may cause a moderate interaction that could exacerbate diseases when taken with Isometheptene
Indacaterol (Compound) causes Atrial fibrillation (Side Effect) and Atrial fibrillation (Side Effect) is caused by Selegiline (Compound) and Selegiline may lead to a major life threatening interaction when taken with Isometheptene
Indacaterol (Compound) binds ADRB1 (Gene) and ADRB1 (Gene) is bound by Bromocriptine (Compound) and Bromocriptine may lead to a major life threatening interaction when taken with Isometheptene