DDInter1439 DDInter1376
Phendimetrazine is a weight loss medication. Phendimetrazine is chemically related to amphetamines and is a Schedule III drug under the Convention on Psychotropic Substances and in the US since 1970.
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26, 2020.[L12573,L12582] The US approval was followed by the approval in Canada on October 2, 2020. In November 2021, ozanimod was also approved by the European Commission for the treatment of adults with relapsing remitting multiple sclerosis.[L39377,L39382] MS is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Inflammatory bowel disease also a chronic inflammatory condition and can cause persistent abdominal pain, diarrhea, bloody stools, and vomiting. In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard in MS therapy. Studies involving patients with inflammatory bowel disease have also shown promising results.[A189318,A189342]
Phendimetrazine {u} (Compound) resembles {v} (Compound) Phenmetrazine
Phendimetrazine {u} (Compound) treats {v} (Disease) obesity
Phendimetrazine {u} (Compound) binds {v} (Gene) SLC6A3
Phendimetrazine {u} (Compound) is included by {v} (Pharmacologic Class) Increased Sympathetic Activity
Phendimetrazine {u} (Compound) causes {v} (Side Effect) Tremor
Phendimetrazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Glipizide
Phendimetrazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Linagliptin
Phendimetrazine {u} may lead to a major life threatening interaction when taken with {v} Fenfluramine
Phendimetrazine {u} may lead to a major life threatening interaction when taken with {v} Methylene blue
Phendimetrazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} and {u} may lead to a major life threatening interaction when taken with {v} Iobenguane
Phendimetrazine (Compound) resembles Phenmetrazine (Compound)
Phendimetrazine (Compound) treats obesity (Disease)
Phendimetrazine (Compound) binds SLC6A3 (Gene)
Phendimetrazine (Compound) is included by Increased Sympathetic Activity (Pharmacologic Class)
Phendimetrazine (Compound) causes Tremor (Side Effect)
Phendimetrazine may cause a moderate interaction that could exacerbate diseases when taken with Glipizide
Phendimetrazine may cause a moderate interaction that could exacerbate diseases when taken with Linagliptin
Phendimetrazine may lead to a major life threatening interaction when taken with Fenfluramine
Phendimetrazine may lead to a major life threatening interaction when taken with Methylene blue
Phendimetrazine may cause a moderate interaction that could exacerbate diseases when taken with Iobenguane and Phendimetrazine may lead to a major life threatening interaction when taken with Iobenguane