DDInter948 DDInter1946
Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. The increased affinity of voriconazole for 14-alpha sterol demethylase makes it useful against some [fluconazole]-resistant organisms. Voriconazole was approved by the FDA under the trade name Vfend on May 24, 2002.
Voriconazole {u} (Compound) binds {v} (Gene) CYP2B6
Voriconazole {u} (Compound) upregulates {v} (Gene) SELL
Voriconazole {u} (Compound) is included by {v} (Pharmacologic Class) Cytochrome P450 2C9 Inhibitors
Voriconazole {u} (Compound) causes {v} (Side Effect) Arthralgia
Voriconazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Darolutamide
Voriconazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cimetidine
Voriconazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methotrexate
Voriconazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Avatrombopag
Voriconazole {u} may lead to a major life threatening interaction when taken with {v} Dasatinib
Voriconazole {u} may lead to a major life threatening interaction when taken with {v} Acetohexamide
Voriconazole (Compound) binds CYP2B6 (Gene)
Voriconazole (Compound) upregulates SELL (Gene)
Voriconazole (Compound) is included by Cytochrome P450 2C9 Inhibitors (Pharmacologic Class)
Voriconazole (Compound) causes Arthralgia (Side Effect)
Voriconazole may cause a minor interaction that can limit clinical effects when taken with Darolutamide
Voriconazole may cause a minor interaction that can limit clinical effects when taken with Cimetidine
Voriconazole may cause a moderate interaction that could exacerbate diseases when taken with Methotrexate
Voriconazole may cause a moderate interaction that could exacerbate diseases when taken with Avatrombopag
Voriconazole may lead to a major life threatening interaction when taken with Dasatinib
Voriconazole may lead to a major life threatening interaction when taken with Acetohexamide