DDInter99 DDInter899
Human tissue plasminogen activator, purified, glycosylated, 527 residues purified from CHO cells. Eminase is a lyophilized (freeze-dried) formulation of anistreplase, the p-anisoyl derivative of the primary Lys-plasminogen-streptokinase activator complex (a complex of Lys-plasminogen and streptokinase). A p-anisoyl group is chemically conjugated to a complex of bacterial-derived streptokinase and human Plasma-derived Lys-plasminogen proteins.
Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase. It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in November 2013 for the treatment of mantle cell lymphoma (MCL) under accelerated approval; however, in April 2023, the drug manufacturer withdrew the accelerated approvals for ibrutinib in the US. Ibrutinib was approved by the EMA in October 2014 and by Health Canada in November 2014. It is currently approved for the treatment of various conditions, such as chronic lymphocytic leukemia (CLL), Waldenström's Macroglobulinemia, and chronic graft versus host disease (cGVHD) in August 2017. Notably, ibrutinib became the first FDA-approved cGVHD treatment for children in August 2017.
Anistreplase {u} may cause a minor interaction that can limit clinical effects when taken with {v} Chamomile
Anistreplase {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Etodolac
Anistreplase {u} may lead to a major life threatening interaction when taken with {v} Tirofiban
Anistreplase {u} may lead to a major life threatening interaction when taken with {v} Lepirudin
Anistreplase may cause a minor interaction that can limit clinical effects when taken with Chamomile
Anistreplase may cause a moderate interaction that could exacerbate diseases when taken with Etodolac
Anistreplase may lead to a major life threatening interaction when taken with Tirofiban
Anistreplase may lead to a major life threatening interaction when taken with Lepirudin