DDInter4 DDInter1570
Synthetic decapeptide antagonist to gonadotropin releasing hormone (GnRH). It is marketed by Praecis Pharmaceuticals as Plenaxis. Praecis announced in June 2006 that it was voluntarily withdrawing the drug from the market.
Chronic angina is a common cardiovascular condition affecting millions worldwide and causes significant disability while interfering with daily activities. Ranolazine is a well-tolerated piperazine derivative used for the management of this condition, offering relief from uncomfortable and debilitating symptoms. With a mechanism of action different from drugs used to treat the same condition, ranolazine is a promising anti-anginal therapy. It was originally approved by the FDA in 2006.
Abarelix {u} may lead to a major life threatening interaction when taken with {v} Methadone
Methadone {u} (Compound) resembles {v} (Compound) Eprazinone
Eprazinone {u} (Compound) resembles {v} (Compound) Ranolazine
Abarelix {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Hydroxyzine
Hydroxyzine {u} (Compound) resembles {v} (Compound) Eprazinone
Eprazinone {u} (Compound) resembles {v} (Compound) Ranolazine
Abarelix {u} may lead to a major life threatening interaction when taken with {v} Methadone
Methadone {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Ranolazine
Abarelix {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Hydroxyzine
Hydroxyzine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Ranolazine
Abarelix {u} may lead to a major life threatening interaction when taken with {v} Methadone
Methadone {u} (Compound) causes {v} (Side Effect) Vomiting
Vomiting {u} (Side Effect) is caused by {v} (Compound) Ranolazine
Abarelix {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Hydroxyzine
Hydroxyzine {u} (Compound) causes {v} (Side Effect) Urticaria
Urticaria {u} (Side Effect) is caused by {v} (Compound) Ranolazine
Abarelix {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Chlorpromazine
Chlorpromazine {u} (Compound) resembles {v} (Compound) Acetophenazine
Acetophenazine {u} (Compound) resembles {v} (Compound) Ranolazine
Abarelix {u} may lead to a major life threatening interaction when taken with {v} Thioridazine
Thioridazine {u} (Compound) upregulates {v} (Gene) HIST2H2BE
HIST2H2BE {u} (Gene) is upregulated by {v} (Compound) Ranolazine
Abarelix {u} may lead to a major life threatening interaction when taken with {v} Thioridazine
Thioridazine {u} (Compound) downregulates {v} (Gene) ATP6V1D
ATP6V1D {u} (Gene) is downregulated by {v} (Compound) Ranolazine
Abarelix {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Propafenone
Propafenone {u} (Compound) resembles {v} (Compound) Carvedilol
Carvedilol {u} (Compound) resembles {v} (Compound) Ranolazine
Abarelix may lead to a major life threatening interaction when taken with Methadone and Methadone (Compound) resembles Eprazinone (Compound) and Eprazinone (Compound) resembles Ranolazine (Compound)
Abarelix may cause a moderate interaction that could exacerbate diseases when taken with Hydroxyzine and Hydroxyzine (Compound) resembles Eprazinone (Compound) and Eprazinone (Compound) resembles Ranolazine (Compound)
Abarelix may lead to a major life threatening interaction when taken with Methadone and Methadone (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Ranolazine (Compound)
Abarelix may cause a moderate interaction that could exacerbate diseases when taken with Hydroxyzine and Hydroxyzine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Ranolazine (Compound)
Abarelix may lead to a major life threatening interaction when taken with Methadone and Methadone (Compound) causes Vomiting (Side Effect) and Vomiting (Side Effect) is caused by Ranolazine (Compound)
Abarelix may cause a moderate interaction that could exacerbate diseases when taken with Hydroxyzine and Hydroxyzine (Compound) causes Urticaria (Side Effect) and Urticaria (Side Effect) is caused by Ranolazine (Compound)
Abarelix may cause a moderate interaction that could exacerbate diseases when taken with Chlorpromazine and Chlorpromazine (Compound) resembles Acetophenazine (Compound) and Acetophenazine (Compound) resembles Ranolazine (Compound)
Abarelix may lead to a major life threatening interaction when taken with Thioridazine and Thioridazine (Compound) upregulates HIST2H2BE (Gene) and HIST2H2BE (Gene) is upregulated by Ranolazine (Compound)
Abarelix may lead to a major life threatening interaction when taken with Thioridazine and Thioridazine (Compound) downregulates ATP6V1D (Gene) and ATP6V1D (Gene) is downregulated by Ranolazine (Compound)
Abarelix may cause a moderate interaction that could exacerbate diseases when taken with Propafenone and Propafenone (Compound) resembles Carvedilol (Compound) and Carvedilol (Compound) resembles Ranolazine (Compound)