DDInter1340 DDInter411
Originally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class, and its approval was followed by the formulation of many other proton pump inhibitor drugs. Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults [FDA label].
A benzodiazepine used to treat various seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop.[FDA Label][L5572,F3763,F3787,F3796] The agent has also been indicated for treating panic disorder.[FDA Label][A175438,L5572,F3763,F3787,F3796] The mechanism of action appears to involve the enhancement of gamma-aminobutyric acid receptor responses.[FDA Label][A175438,A175441,L5572,F3763,F3787,F3796] Since being first patented in 1960 and then released for sale from Roche in the US in 1975,[T469,T472] clonazepam has experienced a storied history in the treatment of the aforementioned medical conditions. Now available as a generic medication, the agent continues to see exceptionally high use as millions of prescriptions are written for the medication internationally every year. Unfortunately, however, like most benzodiazepines, clonazepam use has also been associated with recreational use and drug abuse.[FDA Label][L5572,F3763,F3787,F3796]
Omeprazole {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Clonazepam
Omeprazole {u} (Compound) causes {v} (Side Effect) Increased appetite
Increased appetite {u} (Side Effect) is caused by {v} (Compound) Clonazepam
Omeprazole {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Nitrazepam
Nitrazepam {u} (Compound) resembles {v} (Compound) Clonazepam
Omeprazole {u} (Compound) causes {v} (Side Effect) Increased appetite
Increased appetite {u} (Side Effect) is caused by {v} (Compound) Diazepam
Diazepam {u} (Compound) resembles {v} (Compound) Clonazepam
Omeprazole {u} (Compound) causes {v} (Side Effect) Vision blurred
Vision blurred {u} (Side Effect) is caused by {v} (Compound) Nitrazepam
Nitrazepam {u} (Compound) resembles {v} (Compound) Clonazepam
Omeprazole {u} (Compound) causes {v} (Side Effect) Polyuria
Polyuria {u} (Side Effect) is caused by {v} (Compound) Theophylline
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Clonazepam
Omeprazole {u} (Compound) causes {v} (Side Effect) Vaginal inflammation
Vaginal inflammation {u} (Side Effect) is caused by {v} (Compound) Cetirizine
Cetirizine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clonazepam
Omeprazole {u} (Compound) resembles {v} (Compound) Pantoprazole
Pantoprazole {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Clonazepam
Omeprazole {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Diazepam
Diazepam {u} (Compound) resembles {v} (Compound) Clonazepam
Omeprazole {u} (Compound) causes {v} (Side Effect) Vaginal inflammation
Vaginal inflammation {u} (Side Effect) is caused by {v} (Compound) Bupropion
Bupropion {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clonazepam
Omeprazole (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Clonazepam (Compound)
Omeprazole (Compound) causes Increased appetite (Side Effect) and Increased appetite (Side Effect) is caused by Clonazepam (Compound)
Omeprazole (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Nitrazepam (Compound) and Nitrazepam (Compound) resembles Clonazepam (Compound)
Omeprazole (Compound) causes Increased appetite (Side Effect) and Increased appetite (Side Effect) is caused by Diazepam (Compound) and Diazepam (Compound) resembles Clonazepam (Compound)
Omeprazole (Compound) causes Vision blurred (Side Effect) and Vision blurred (Side Effect) is caused by Nitrazepam (Compound) and Nitrazepam (Compound) resembles Clonazepam (Compound)
Omeprazole (Compound) causes Polyuria (Side Effect) and Polyuria (Side Effect) is caused by Theophylline (Compound) and Theophylline may cause a minor interaction that can limit clinical effects when taken with Clonazepam
Omeprazole (Compound) causes Vaginal inflammation (Side Effect) and Vaginal inflammation (Side Effect) is caused by Cetirizine (Compound) and Cetirizine may cause a moderate interaction that could exacerbate diseases when taken with Clonazepam
Omeprazole (Compound) resembles Pantoprazole (Compound) and Pantoprazole (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Clonazepam (Compound)
Omeprazole (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Diazepam (Compound) and Diazepam (Compound) resembles Clonazepam (Compound)
Omeprazole (Compound) causes Vaginal inflammation (Side Effect) and Vaginal inflammation (Side Effect) is caused by Bupropion (Compound) and Bupropion may cause a moderate interaction that could exacerbate diseases when taken with Clonazepam