DDInter740 DDInter1917
Flecainide is a Class I anti-arrhythmic agent like [encainide] and [propafenone]. Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter.[L8878,L5056] Flecainide was granted FDA approval on 31 October 1985.
Vandetanib is an oral once-daily kinase inhibitor of tumour angiogenesis and tumour cell proliferation with the potential for use in a broad range of tumour types. On April 6 2011, vandetanib was approved by the FDA to treat nonresectable, locally advanced, or metastatic medullary thyroid cancer in adult patients.
Flecainide {u} (Compound) causes {v} (Side Effect) Pain
Pain {u} (Side Effect) is caused by {v} (Compound) Vandetanib
Flecainide {u} (Compound) resembles {v} (Compound) Mefloquine
Mefloquine {u} may lead to a major life threatening interaction when taken with {v} Vandetanib
Flecainide {u} (Compound) causes {v} (Side Effect) Pain
Pain {u} (Side Effect) is caused by {v} (Compound) Erlotinib
Erlotinib {u} (Compound) resembles {v} (Compound) Vandetanib
Flecainide {u} (Compound) causes {v} (Side Effect) Paraesthesia
Paraesthesia {u} (Side Effect) is caused by {v} (Compound) Esomeprazole
Esomeprazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Vandetanib
Flecainide {u} (Compound) causes {v} (Side Effect) Corneal deposits
Corneal deposits {u} (Side Effect) is caused by {v} (Compound) Rifabutin
Rifabutin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Vandetanib
Flecainide {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Clozapine
Clozapine {u} may lead to a major life threatening interaction when taken with {v} Vandetanib
Flecainide {u} (Compound) resembles {v} (Compound) Mefloquine
Mefloquine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Vandetanib
Flecainide {u} (Compound) causes {v} (Side Effect) Corneal deposits
Corneal deposits {u} (Side Effect) is caused by {v} (Compound) Trifluoperazine
Trifluoperazine {u} may lead to a major life threatening interaction when taken with {v} Vandetanib
Flecainide {u} (Compound) causes {v} (Side Effect) Balance disorder
Balance disorder {u} (Side Effect) is caused by {v} (Compound) Dalfampridine
Dalfampridine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Vandetanib
Flecainide {u} (Compound) binds {v} (Gene) SCN4A
SCN4A {u} (Gene) is bound by {v} (Compound) Phenytoin
Phenytoin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Vandetanib
Flecainide (Compound) causes Pain (Side Effect) and Pain (Side Effect) is caused by Vandetanib (Compound)
Flecainide (Compound) resembles Mefloquine (Compound) and Mefloquine may lead to a major life threatening interaction when taken with Vandetanib
Flecainide (Compound) causes Pain (Side Effect) and Pain (Side Effect) is caused by Erlotinib (Compound) and Erlotinib (Compound) resembles Vandetanib (Compound)
Flecainide (Compound) causes Paraesthesia (Side Effect) and Paraesthesia (Side Effect) is caused by Esomeprazole (Compound) and Esomeprazole may cause a minor interaction that can limit clinical effects when taken with Vandetanib
Flecainide (Compound) causes Corneal deposits (Side Effect) and Corneal deposits (Side Effect) is caused by Rifabutin (Compound) and Rifabutin may cause a moderate interaction that could exacerbate diseases when taken with Vandetanib
Flecainide (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Clozapine (Compound) and Clozapine may lead to a major life threatening interaction when taken with Vandetanib
Flecainide (Compound) resembles Mefloquine (Compound) and Mefloquine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Vandetanib (Compound)
Flecainide (Compound) causes Corneal deposits (Side Effect) and Corneal deposits (Side Effect) is caused by Trifluoperazine (Compound) and Trifluoperazine may lead to a major life threatening interaction when taken with Vandetanib
Flecainide (Compound) causes Balance disorder (Side Effect) and Balance disorder (Side Effect) is caused by Dalfampridine (Compound) and Dalfampridine may cause a moderate interaction that could exacerbate diseases when taken with Vandetanib
Flecainide (Compound) binds SCN4A (Gene) and SCN4A (Gene) is bound by Phenytoin (Compound) and Phenytoin may cause a moderate interaction that could exacerbate diseases when taken with Vandetanib