DDInter1441 DDInter1960
Phenindamine is an antihistamine. Phenindamine blocks the effects of the naturally occurring chemical histamine in your body. Antihistamines such as phenindamine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release. It is used to treat sneezing, runny nose, itching, watery eyes, hives, rashes, itching, and other symptoms of allergies and the common cold. Symptoms of a phenindamine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures.
Ziconotide (also known as SNX-111) is a neurotoxic peptide derived from the cone snail _Conus magus_ comprising 25 amino acids with three disulphide bonds.[A202835, L13389] Other such peptides, collectively termed conotoxins, exist, and some have shown efficacy in binding specific subsets of calcium channels; ziconotide is used in part because it can be synthesized without loss of proper bond formation or structural elements.[A202829, A202832] Ziconotide is used to manage severe chronic pain refractory to other methods, through its ability to inhibit N-type calcium channels involved in nociceptive signalling.[A202829, A202835, A202838, A202841, A202850, A202859, L13389] Ziconotide was granted FDA approval on December 28, 2004 for marketing by TerSera therapeutics LLC. under the name Prialt. To date, ziconotide is the only calcium channel blocking peptide approved for use by the FDA.
Phenindamine {u} (Compound) resembles {v} (Compound) Mirtazapine
Phenindamine {u} (Compound) resembles {v} (Compound) Metixene
Phenindamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Benzatropine
Phenindamine {u} (Compound) binds {v} (Gene) HRH1
Phenindamine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Hyaluronidase
Phenindamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opicapone
Phenindamine {u} may lead to a major life threatening interaction when taken with {v} Zonisamide
Phenindamine {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amitriptyline
Phenindamine (Compound) resembles Mirtazapine (Compound)
Phenindamine (Compound) resembles Metixene (Compound)
Phenindamine may cause a moderate interaction that could exacerbate diseases when taken with Benzatropine
Phenindamine (Compound) binds HRH1 (Gene)
Phenindamine may cause a minor interaction that can limit clinical effects when taken with Hyaluronidase
Phenindamine may cause a moderate interaction that could exacerbate diseases when taken with Opicapone
Phenindamine may lead to a major life threatening interaction when taken with Zonisamide
Phenindamine (Compound) resembles Amitriptyline (Compound) and Phenindamine may cause a moderate interaction that could exacerbate diseases when taken with Amitriptyline