DDInter695 DDInter154
An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
Azelastine is a phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position. It has a role as a H1-receptor antagonist, an anti-allergic agent, an anti-asthmatic drug, a bronchodilator agent, a platelet aggregation inhibitor and an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. It is a member of phthalazines, a tertiary amino compound and a member of monochlorobenzenes.
Ethosuximide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clemastine
Clemastine {u} (Compound) resembles {v} (Compound) Azelastine
Ethosuximide {u} (Compound) binds {v} (Gene) CYP2E1
CYP2E1 {u} (Gene) is bound by {v} (Compound) Azelastine
Ethosuximide {u} (Compound) causes {v} (Side Effect) Headache
Headache {u} (Side Effect) is caused by {v} (Compound) Azelastine
Ethosuximide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clemastine
Clemastine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) Azelastine
Ethosuximide {u} (Compound) binds {v} (Gene) CYP2E1
CYP2E1 {u} (Gene) is bound by {v} (Compound) Clozapine
Clozapine {u} (Compound) resembles {v} (Compound) Azelastine
Ethosuximide {u} (Compound) binds {v} (Gene) CYP3A5
CYP3A5 {u} (Gene) regulates {v} (Gene) EPCAM
EPCAM {u} (Gene) is upregulated by {v} (Compound) Azelastine
Ethosuximide {u} (Compound) causes {v} (Side Effect) Headache
Headache {u} (Side Effect) is caused by {v} (Compound) Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) Azelastine
Ethosuximide {u} (Compound) resembles {v} (Compound) Methyprylon
Methyprylon {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Azelastine
Ethosuximide {u} (Compound) upregulates {v} (Gene) ZNF586
ZNF586 {u} (Gene) is regulated by {v} (Gene) NOSIP
NOSIP {u} (Gene) is downregulated by {v} (Compound) Azelastine
Ethosuximide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clemastine
Clemastine {u} (Compound) resembles {v} (Compound) Buclizine
Buclizine {u} (Compound) resembles {v} (Compound) Azelastine
Ethosuximide may cause a moderate interaction that could exacerbate diseases when taken with Clemastine and Clemastine (Compound) resembles Azelastine (Compound)
Ethosuximide (Compound) binds CYP2E1 (Gene) and CYP2E1 (Gene) is bound by Azelastine (Compound)
Ethosuximide (Compound) causes Headache (Side Effect) and Headache (Side Effect) is caused by Azelastine (Compound)
Ethosuximide may cause a moderate interaction that could exacerbate diseases when taken with Clemastine and Clemastine may cause a moderate interaction that could exacerbate diseases when taken with Loxapine and Loxapine (Compound) resembles Azelastine (Compound)
Ethosuximide (Compound) binds CYP2E1 (Gene) and CYP2E1 (Gene) is bound by Clozapine (Compound) and Clozapine (Compound) resembles Azelastine (Compound)
Ethosuximide (Compound) binds CYP3A5 (Gene) and CYP3A5 (Gene) regulates EPCAM (Gene) and EPCAM (Gene) is upregulated by Azelastine (Compound)
Ethosuximide (Compound) causes Headache (Side Effect) and Headache (Side Effect) is caused by Loxapine (Compound) and Loxapine (Compound) resembles Azelastine (Compound)
Ethosuximide (Compound) resembles Methyprylon (Compound) and Methyprylon (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Azelastine (Compound)
Ethosuximide (Compound) upregulates ZNF586 (Gene) and ZNF586 (Gene) is regulated by NOSIP (Gene) and NOSIP (Gene) is downregulated by Azelastine (Compound)
Ethosuximide may cause a moderate interaction that could exacerbate diseases when taken with Clemastine and Clemastine (Compound) resembles Buclizine (Compound) and Buclizine (Compound) resembles Azelastine (Compound)