DDInter1200 DDInter1180
Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US. Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.
Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Metoprolol {u} (Compound) resembles {v} (Compound) Oxprenolol
Metoprolol {u} (Compound) resembles {v} (Compound) Metipranolol
Metoprolol {u} (Compound) treats {v} (Disease) hypertension
Metoprolol {u} (Compound) binds {v} (Gene) SLC22A2
Metoprolol {u} (Compound) upregulates {v} (Gene) HOOK2
Metoprolol {u} (Compound) downregulates {v} (Gene) LAP3
Metoprolol {u} (Compound) causes {v} (Side Effect) Coma
Metoprolol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Levothyroxine
Metoprolol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Glucagon
Metoprolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pasireotide
Metoprolol (Compound) resembles Oxprenolol (Compound)
Metoprolol (Compound) resembles Metipranolol (Compound)
Metoprolol (Compound) treats hypertension (Disease)
Metoprolol (Compound) binds SLC22A2 (Gene)
Metoprolol (Compound) upregulates HOOK2 (Gene)
Metoprolol (Compound) downregulates LAP3 (Gene)
Metoprolol (Compound) causes Coma (Side Effect)
Metoprolol may cause a minor interaction that can limit clinical effects when taken with Levothyroxine
Metoprolol may cause a minor interaction that can limit clinical effects when taken with Glucagon
Metoprolol may cause a moderate interaction that could exacerbate diseases when taken with Pasireotide