DDInter1266 DDInter1513
Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given its overall tolerability and effectiveness, naproxen can be considered a first line treatment for a variety of clinical situations requiring analgesia. Naproxen is available in both immediate and delayed release formulations, in combination with sumatriptan to treat migraines, and in combination with esomeprazole to lower the risk of developing gastric ulcers.
Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Naproxen {u} (Compound) palliates {v} (Disease) systemic lupus erythematosus
systemic lupus erythematosus {u} (Disease) is treated by {v} (Compound) Prednisolone
Naproxen {u} (Compound) treats {v} (Disease) gout
gout {u} (Disease) is treated by {v} (Compound) Prednisolone
Naproxen {u} (Compound) binds {v} (Gene) SLCO1A2
SLCO1A2 {u} (Gene) is bound by {v} (Compound) Prednisolone
Naproxen {u} (Compound) causes {v} (Side Effect) Urticaria
Urticaria {u} (Side Effect) is caused by {v} (Compound) Prednisolone
Naproxen {u} (Compound) resembles {v} (Compound) Nabumetone
Nabumetone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Prednisolone
Naproxen {u} (Compound) resembles {v} (Compound) Ketoprofen
Ketoprofen {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Prednisolone
Naproxen {u} (Compound) palliates {v} (Disease) systemic lupus erythematosus
systemic lupus erythematosus {u} (Disease) is treated by {v} (Compound) Triamcinolone
Triamcinolone {u} (Compound) resembles {v} (Compound) Prednisolone
Naproxen {u} (Compound) treats {v} (Disease) gout
gout {u} (Disease) is treated by {v} (Compound) Hydrocortisone
Hydrocortisone {u} (Compound) resembles {v} (Compound) Prednisolone
Naproxen {u} (Compound) binds {v} (Gene) SLCO1A2
SLCO1A2 {u} (Gene) is bound by {v} (Compound) Testosterone
Testosterone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Prednisolone
Naproxen {u} (Compound) causes {v} (Side Effect) Urticaria
Urticaria {u} (Side Effect) is caused by {v} (Compound) Progesterone
Progesterone {u} (Compound) resembles {v} (Compound) Prednisolone
Naproxen (Compound) palliates systemic lupus erythematosus (Disease) and systemic lupus erythematosus (Disease) is treated by Prednisolone (Compound)
Naproxen (Compound) treats gout (Disease) and gout (Disease) is treated by Prednisolone (Compound)
Naproxen (Compound) binds SLCO1A2 (Gene) and SLCO1A2 (Gene) is bound by Prednisolone (Compound)
Naproxen (Compound) causes Urticaria (Side Effect) and Urticaria (Side Effect) is caused by Prednisolone (Compound)
Naproxen (Compound) resembles Nabumetone (Compound) and Nabumetone may cause a moderate interaction that could exacerbate diseases when taken with Prednisolone
Naproxen (Compound) resembles Ketoprofen (Compound) and Ketoprofen may cause a moderate interaction that could exacerbate diseases when taken with Prednisolone
Naproxen (Compound) palliates systemic lupus erythematosus (Disease) and systemic lupus erythematosus (Disease) is treated by Triamcinolone (Compound) and Triamcinolone (Compound) resembles Prednisolone (Compound)
Naproxen (Compound) treats gout (Disease) and gout (Disease) is treated by Hydrocortisone (Compound) and Hydrocortisone (Compound) resembles Prednisolone (Compound)
Naproxen (Compound) binds SLCO1A2 (Gene) and SLCO1A2 (Gene) is bound by Testosterone (Compound) and Testosterone may cause a moderate interaction that could exacerbate diseases when taken with Prednisolone
Naproxen (Compound) causes Urticaria (Side Effect) and Urticaria (Side Effect) is caused by Progesterone (Compound) and Progesterone (Compound) resembles Prednisolone (Compound)