DDInter1133 DDInter1625
A vesicant and necrotizing irritant destructive to mucous membranes, mechlorethamine is an alkylating drug. It was formerly used as a war gas. The hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. It causes severe gastrointestinal and bone marrow damage. The FDA granted marketing approval for the orphan drug Valchlor (mechlorethamine) gel on August 23, 2013 for the topical treatment of stage IA and IB mycosis fungoides-type cutaneous T-cell lymphoma (CTCL) in patients who have received prior skin-directed therapy. Each tube of Valchlor contains 0.016% of mechlorethamine which is equivalent to 0.02% mechlorethamine HCl.
Rubella virus vaccine is a live attenuated virus vaccine for active immunization against rubella (German measles) that is subcutaneously administered. It is prepared from RA 27/3 strain of live attenuated rubella virus. Rubella is a common childhood disease, caused by rubella virus (togavirus).
Mechlorethamine {u} (Compound) resembles {v} (Compound) Cyclophosphamide
Mechlorethamine {u} (Compound) treats {v} (Disease) hematologic cancer
Mechlorethamine {u} (Compound) is included by {v} (Pharmacologic Class) Alkylating Activity
Mechlorethamine {u} (Compound) causes {v} (Side Effect) Thrombosis
Mechlorethamine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Delafloxacin
Mechlorethamine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Warfarin
Mechlorethamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Daunorubicin
Mechlorethamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ustekinumab
Mechlorethamine {u} may lead to a major life threatening interaction when taken with {v} Clozapine
Mechlorethamine {u} may lead to a major life threatening interaction when taken with {v} Leflunomide
Mechlorethamine (Compound) resembles Cyclophosphamide (Compound)
Mechlorethamine (Compound) treats hematologic cancer (Disease)
Mechlorethamine (Compound) is included by Alkylating Activity (Pharmacologic Class)
Mechlorethamine (Compound) causes Thrombosis (Side Effect)
Mechlorethamine may cause a minor interaction that can limit clinical effects when taken with Delafloxacin
Mechlorethamine may cause a minor interaction that can limit clinical effects when taken with Warfarin
Mechlorethamine may cause a moderate interaction that could exacerbate diseases when taken with Daunorubicin
Mechlorethamine may cause a moderate interaction that could exacerbate diseases when taken with Ustekinumab
Mechlorethamine may lead to a major life threatening interaction when taken with Clozapine
Mechlorethamine may lead to a major life threatening interaction when taken with Leflunomide