DDInter1693 DDInter1376
Sodium Sulfate Anhydrous is the anhydrous, sodium salt form of sulfuric acid. Sodium sulfate anhydrous disassociates in water to provide sodium ions and sulfate ions. Sodium ion is the principal cation of the extracellular fluid and plays a large part in the therapy of fluid and electrolyte disturbances. Sodium sulfate anhydrous is an electrolyte replenisher and is used in isosmotic solutions so that administration does not disturb normal electrolyte balance and does not lead to absorption or excretion of water and ions.
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26, 2020.[L12573,L12582] The US approval was followed by the approval in Canada on October 2, 2020. In November 2021, ozanimod was also approved by the European Commission for the treatment of adults with relapsing remitting multiple sclerosis.[L39377,L39382] MS is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Inflammatory bowel disease also a chronic inflammatory condition and can cause persistent abdominal pain, diarrhea, bloody stools, and vomiting. In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard in MS therapy. Studies involving patients with inflammatory bowel disease have also shown promising results.[A189318,A189342]
Sodium sulfate {u} may cause a minor interaction that can limit clinical effects when taken with {v} Digitoxin
Sodium sulfate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxamniquine
Sodium sulfate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fostemsavir
Sodium sulfate {u} may lead to a major life threatening interaction when taken with {v} Dronedarone
Sodium sulfate may cause a minor interaction that can limit clinical effects when taken with Digitoxin
Sodium sulfate may cause a moderate interaction that could exacerbate diseases when taken with Oxamniquine
Sodium sulfate may cause a moderate interaction that could exacerbate diseases when taken with Fostemsavir
Sodium sulfate may lead to a major life threatening interaction when taken with Dronedarone