DDInter1791 DDInter1620
A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly for asthma, bronchospasm, and COPD.
Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Tocainide
Tocainide {u} (Compound) resembles {v} (Compound) Ropivacaine
Theophylline {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Ropivacaine
Theophylline {u} (Compound) causes {v} (Side Effect) Rash
Rash {u} (Side Effect) is caused by {v} (Compound) Ropivacaine
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Tocainide
Tocainide {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lidocaine
Lidocaine {u} (Compound) resembles {v} (Compound) Ropivacaine
Theophylline {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Lidocaine
Lidocaine {u} (Compound) resembles {v} (Compound) Ropivacaine
Theophylline {u} (Compound) causes {v} (Side Effect) Rash
Rash {u} (Side Effect) is caused by {v} (Compound) Lidocaine
Lidocaine {u} (Compound) resembles {v} (Compound) Ropivacaine
Theophylline {u} (Compound) resembles {v} (Compound) Dyphylline
Dyphylline {u} (Compound) causes {v} (Side Effect) Tachycardia
Tachycardia {u} (Side Effect) is caused by {v} (Compound) Ropivacaine
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Tocainide
Tocainide {u} (Compound) resembles {v} (Compound) Levobupivacaine
Levobupivacaine {u} (Compound) resembles {v} (Compound) Ropivacaine
Theophylline {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Bupivacaine
Bupivacaine {u} (Compound) resembles {v} (Compound) Ropivacaine
Theophylline {u} (Compound) causes {v} (Side Effect) Haematuria
Haematuria {u} (Side Effect) is caused by {v} (Compound) Bupivacaine
Bupivacaine {u} (Compound) resembles {v} (Compound) Ropivacaine
Theophylline may cause a minor interaction that can limit clinical effects when taken with Tocainide and Tocainide (Compound) resembles Ropivacaine (Compound)
Theophylline (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Ropivacaine (Compound)
Theophylline (Compound) causes Rash (Side Effect) and Rash (Side Effect) is caused by Ropivacaine (Compound)
Theophylline may cause a minor interaction that can limit clinical effects when taken with Tocainide and Tocainide (Compound) resembles Lidocaine (Compound) and Tocainide may cause a moderate interaction that could exacerbate diseases when taken with Lidocaine and Lidocaine (Compound) resembles Ropivacaine (Compound)
Theophylline (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Lidocaine (Compound) and Lidocaine (Compound) resembles Ropivacaine (Compound)
Theophylline (Compound) causes Rash (Side Effect) and Rash (Side Effect) is caused by Lidocaine (Compound) and Lidocaine (Compound) resembles Ropivacaine (Compound)
Theophylline (Compound) resembles Dyphylline (Compound) and Dyphylline (Compound) causes Tachycardia (Side Effect) and Tachycardia (Side Effect) is caused by Ropivacaine (Compound)
Theophylline may cause a minor interaction that can limit clinical effects when taken with Tocainide and Tocainide (Compound) resembles Levobupivacaine (Compound) and Levobupivacaine (Compound) resembles Ropivacaine (Compound)
Theophylline (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Bupivacaine (Compound) and Bupivacaine (Compound) resembles Ropivacaine (Compound)
Theophylline (Compound) causes Haematuria (Side Effect) and Haematuria (Side Effect) is caused by Bupivacaine (Compound) and Bupivacaine (Compound) resembles Ropivacaine (Compound)