DDInter458 DDInter1663
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus _Beauveria nivea_. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Cyclosporine {u} (Compound) causes {v} (Side Effect) Dermatitis
Dermatitis {u} (Side Effect) is caused by {v} (Compound) Sevelamer
Cyclosporine {u} (Compound) causes {v} (Side Effect) Dermatitis
Dermatitis {u} (Side Effect) is caused by {v} (Compound) Mycophenolic acid
Mycophenolic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sevelamer
Cyclosporine {u} (Compound) treats {v} (Disease) psoriasis
psoriasis {u} (Disease) is treated by {v} (Compound) Mycophenolic acid
Mycophenolic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sevelamer
Cyclosporine {u} (Compound) upregulates {v} (Gene) COL11A1
COL11A1 {u} (Gene) is upregulated by {v} (Compound) Mycophenolic acid
Mycophenolic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sevelamer
Cyclosporine {u} (Compound) causes {v} (Side Effect) Abdominal distension
Abdominal distension {u} (Side Effect) is caused by {v} (Compound) Moxifloxacin
Moxifloxacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sevelamer
Cyclosporine {u} (Compound) treats {v} (Disease) psoriasis
psoriasis {u} (Disease) is treated by {v} (Compound) Cholecalciferol
Cholecalciferol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sevelamer
Cyclosporine {u} (Compound) downregulates {v} (Gene) CCNE2
CCNE2 {u} (Gene) is upregulated by {v} (Compound) Mycophenolic acid
Mycophenolic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sevelamer
Cyclosporine {u} (Compound) binds {v} (Gene) FKBP1B
FKBP1B {u} (Gene) is upregulated by {v} (Compound) Mycophenolic acid
Mycophenolic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sevelamer
Cyclosporine {u} (Compound) upregulates {v} (Gene) CTSL
CTSL {u} (Gene) is downregulated by {v} (Compound) Gatifloxacin
Gatifloxacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sevelamer
Cyclosporine {u} (Compound) downregulates {v} (Gene) LMNB2
LMNB2 {u} (Gene) is downregulated by {v} (Compound) Mycophenolic acid
Mycophenolic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sevelamer
Cyclosporine (Compound) causes Dermatitis (Side Effect) and Dermatitis (Side Effect) is caused by Sevelamer (Compound)
Cyclosporine (Compound) causes Dermatitis (Side Effect) and Dermatitis (Side Effect) is caused by Mycophenolic acid (Compound) and Mycophenolic acid may cause a moderate interaction that could exacerbate diseases when taken with Sevelamer
Cyclosporine (Compound) treats psoriasis (Disease) and psoriasis (Disease) is treated by Mycophenolic acid (Compound) and Mycophenolic acid may cause a moderate interaction that could exacerbate diseases when taken with Sevelamer
Cyclosporine (Compound) upregulates COL11A1 (Gene) and COL11A1 (Gene) is upregulated by Mycophenolic acid (Compound) and Mycophenolic acid may cause a moderate interaction that could exacerbate diseases when taken with Sevelamer
Cyclosporine (Compound) causes Abdominal distension (Side Effect) and Abdominal distension (Side Effect) is caused by Moxifloxacin (Compound) and Moxifloxacin may cause a moderate interaction that could exacerbate diseases when taken with Sevelamer
Cyclosporine (Compound) treats psoriasis (Disease) and psoriasis (Disease) is treated by Cholecalciferol (Compound) and Cholecalciferol may cause a moderate interaction that could exacerbate diseases when taken with Sevelamer
Cyclosporine (Compound) downregulates CCNE2 (Gene) and CCNE2 (Gene) is upregulated by Mycophenolic acid (Compound) and Mycophenolic acid may cause a moderate interaction that could exacerbate diseases when taken with Sevelamer
Cyclosporine (Compound) binds FKBP1B (Gene) and FKBP1B (Gene) is upregulated by Mycophenolic acid (Compound) and Mycophenolic acid may cause a moderate interaction that could exacerbate diseases when taken with Sevelamer
Cyclosporine (Compound) upregulates CTSL (Gene) and CTSL (Gene) is downregulated by Gatifloxacin (Compound) and Gatifloxacin may cause a moderate interaction that could exacerbate diseases when taken with Sevelamer
Cyclosporine (Compound) downregulates LMNB2 (Gene) and LMNB2 (Gene) is downregulated by Mycophenolic acid (Compound) and Mycophenolic acid may cause a moderate interaction that could exacerbate diseases when taken with Sevelamer