DDInter458 DDInter1473
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus _Beauveria nivea_. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
Pipecuronium is a piperazinyl androstane derivative which is a non-depolarizing neuromuscular blocking agent.
Cyclosporine {u} (Compound) downregulates {v} (Gene) CDC20
CDC20 {u} (Gene) is downregulated by {v} (Compound) Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Cyclosporine {u} (Compound) causes {v} (Side Effect) Flushing
Flushing {u} (Side Effect) is caused by {v} (Compound) Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Cyclosporine {u} (Compound) causes {v} (Side Effect) Anaphylactoid reaction
Anaphylactoid reaction {u} (Side Effect) is caused by {v} (Compound) Rocuronium
Rocuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Cyclosporine {u} (Compound) binds {v} (Gene) SLCO1A2
SLCO1A2 {u} (Gene) is bound by {v} (Compound) Rocuronium
Rocuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Cyclosporine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Vecuronium
Vecuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Cyclosporine {u} (Compound) upregulates {v} (Gene) WDR45
WDR45 {u} (Gene) covaries with {v} (Gene) CHRM3
CHRM3 {u} (Gene) is bound by {v} (Compound) Pipecuronium
Cyclosporine {u} (Compound) downregulates {v} (Gene) POLE2
POLE2 {u} (Gene) is regulated by {v} (Gene) CHRM3
CHRM3 {u} (Gene) is bound by {v} (Compound) Pipecuronium
Cyclosporine (Compound) downregulates CDC20 (Gene) and CDC20 (Gene) is downregulated by Pancuronium (Compound) and Pancuronium (Compound) resembles Pipecuronium (Compound)
Cyclosporine (Compound) causes Flushing (Side Effect) and Flushing (Side Effect) is caused by Pancuronium (Compound) and Pancuronium (Compound) resembles Pipecuronium (Compound)
Cyclosporine (Compound) causes Anaphylactoid reaction (Side Effect) and Anaphylactoid reaction (Side Effect) is caused by Rocuronium (Compound) and Rocuronium (Compound) resembles Pipecuronium (Compound)
Cyclosporine (Compound) binds SLCO1A2 (Gene) and SLCO1A2 (Gene) is bound by Rocuronium (Compound) and Rocuronium (Compound) resembles Pipecuronium (Compound)
Cyclosporine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Vecuronium (Compound) and Vecuronium (Compound) resembles Pipecuronium (Compound)
Cyclosporine (Compound) upregulates WDR45 (Gene) and WDR45 (Gene) covaries with CHRM3 (Gene) and CHRM3 (Gene) is bound by Pipecuronium (Compound)
Cyclosporine (Compound) downregulates POLE2 (Gene) and POLE2 (Gene) is regulated by CHRM3 (Gene) and CHRM3 (Gene) is bound by Pipecuronium (Compound)