DDInter407 DDInter1960
Clofedanol is a centrally-acting cough suppressant available in Canada under the trade name Ulone. It is not available in the United States.
Ziconotide (also known as SNX-111) is a neurotoxic peptide derived from the cone snail _Conus magus_ comprising 25 amino acids with three disulphide bonds.[A202835, L13389] Other such peptides, collectively termed conotoxins, exist, and some have shown efficacy in binding specific subsets of calcium channels; ziconotide is used in part because it can be synthesized without loss of proper bond formation or structural elements.[A202829, A202832] Ziconotide is used to manage severe chronic pain refractory to other methods, through its ability to inhibit N-type calcium channels involved in nociceptive signalling.[A202829, A202835, A202838, A202841, A202850, A202859, L13389] Ziconotide was granted FDA approval on December 28, 2004 for marketing by TerSera therapeutics LLC. under the name Prialt. To date, ziconotide is the only calcium channel blocking peptide approved for use by the FDA.
Clofedanol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Diphenhydramine
Clofedanol {u} (Compound) resembles {v} (Compound) Dextropropoxyphene
Clofedanol {u} (Compound) resembles {v} (Compound) Toremifene
Clofedanol {u} (Compound) binds {v} (Gene) HRH1
Clofedanol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Suvorexant
Clofedanol {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Carbinoxamine
Clofedanol may cause a moderate interaction that could exacerbate diseases when taken with Diphenhydramine
Clofedanol (Compound) resembles Dextropropoxyphene (Compound)
Clofedanol (Compound) resembles Toremifene (Compound)
Clofedanol (Compound) binds HRH1 (Gene)
Clofedanol may cause a moderate interaction that could exacerbate diseases when taken with Suvorexant
Clofedanol (Compound) resembles Carbinoxamine (Compound) and Clofedanol may cause a moderate interaction that could exacerbate diseases when taken with Carbinoxamine