DDInter1206 DDInter178
Antiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.
Bendamustine is a nitrogen mustard drug indicated for use in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed during or within six months of treatment with rituximab or a rituximab-containing regimen. Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases resulting in cell death. It is active against both active and quiescent cells, although the exact mechanism of action is unknown.
Mexiletine {u} (Compound) resembles {v} (Compound) Tocainide
Mexiletine {u} (Compound) binds {v} (Gene) AHR
Mexiletine {u} (Compound) upregulates {v} (Gene) CNOT4
Mexiletine {u} (Compound) downregulates {v} (Gene) ITGB1BP1
Mexiletine {u} (Compound) causes {v} (Side Effect) Thrombocytopenia
Mexiletine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ammonium chloride
Mexiletine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Methionine
Mexiletine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Octreotide
Mexiletine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lanreotide
Mexiletine {u} may lead to a major life threatening interaction when taken with {v} Theophylline
Mexiletine (Compound) resembles Tocainide (Compound)
Mexiletine (Compound) binds AHR (Gene)
Mexiletine (Compound) upregulates CNOT4 (Gene)
Mexiletine (Compound) downregulates ITGB1BP1 (Gene)
Mexiletine (Compound) causes Thrombocytopenia (Side Effect)
Mexiletine may cause a minor interaction that can limit clinical effects when taken with Ammonium chloride
Mexiletine may cause a minor interaction that can limit clinical effects when taken with Methionine
Mexiletine may cause a moderate interaction that could exacerbate diseases when taken with Octreotide
Mexiletine may cause a moderate interaction that could exacerbate diseases when taken with Lanreotide
Mexiletine may lead to a major life threatening interaction when taken with Theophylline