DDInter1759 DDInter669
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arterial blood pressure.[A1489,A1490] Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects.
Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes mellitus. It works to block glucose reabsorption from the glomerulus. Ertugliflozin was first approved by the FDA in December 2017.[A261951, L1132] It was also approved by the European Commission in March 2018.
Telmisartan {u} (Compound) resembles {v} (Compound) Olmesartan
Olmesartan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ertugliflozin
Telmisartan {u} (Compound) resembles {v} (Compound) Olmesartan
Olmesartan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Betamethasone
Betamethasone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ertugliflozin
Telmisartan {u} (Compound) resembles {v} (Compound) Losartan
Losartan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Betamethasone
Betamethasone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ertugliflozin
Telmisartan {u} (Compound) resembles {v} (Compound) Candesartan
Candesartan {u} (Compound) resembles {v} (Compound) Azilsartan medoxomil
Azilsartan medoxomil {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ertugliflozin
Telmisartan {u} (Compound) resembles {v} (Compound) Losartan
Losartan {u} (Compound) resembles {v} (Compound) Olmesartan
Olmesartan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ertugliflozin
Telmisartan {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Nicardipine
Nicardipine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ertugliflozin
Telmisartan {u} (Compound) binds {v} (Gene) ABCG2
ABCG2 {u} (Gene) is bound by {v} (Compound) Conjugated estrogens
Conjugated estrogens {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ertugliflozin
Telmisartan {u} (Compound) treats {v} (Disease) coronary artery disease
coronary artery disease {u} (Disease) is palliated by {v} (Compound) Isosorbide mononitrate
Isosorbide mononitrate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ertugliflozin
Telmisartan {u} (Compound) is included by {v} (Pharmacologic Class) Angiotensin 2 Receptor Antagonists
Angiotensin 2 Receptor Antagonists {u} (Pharmacologic Class) includes {v} (Compound) Eprosartan
Eprosartan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ertugliflozin
Telmisartan {u} (Compound) binds {v} (Gene) PPARG
PPARG {u} (Gene) is upregulated by {v} (Compound) Triamcinolone
Triamcinolone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ertugliflozin
Telmisartan (Compound) resembles Olmesartan (Compound) and Olmesartan may cause a moderate interaction that could exacerbate diseases when taken with Ertugliflozin
Telmisartan (Compound) resembles Olmesartan (Compound) and Olmesartan may cause a moderate interaction that could exacerbate diseases when taken with Betamethasone and Betamethasone may cause a moderate interaction that could exacerbate diseases when taken with Ertugliflozin
Telmisartan (Compound) resembles Losartan (Compound) and Losartan may cause a moderate interaction that could exacerbate diseases when taken with Betamethasone and Betamethasone may cause a moderate interaction that could exacerbate diseases when taken with Ertugliflozin
Telmisartan (Compound) resembles Candesartan (Compound) and Candesartan (Compound) resembles Azilsartan medoxomil (Compound) and Azilsartan medoxomil may cause a moderate interaction that could exacerbate diseases when taken with Ertugliflozin
Telmisartan (Compound) resembles Losartan (Compound) and Losartan (Compound) resembles Olmesartan (Compound) and Olmesartan may cause a moderate interaction that could exacerbate diseases when taken with Ertugliflozin
Telmisartan (Compound) treats hypertension (Disease) and hypertension (Disease) is treated by Nicardipine (Compound) and Nicardipine may cause a moderate interaction that could exacerbate diseases when taken with Ertugliflozin
Telmisartan (Compound) binds ABCG2 (Gene) and ABCG2 (Gene) is bound by Conjugated estrogens (Compound) and Conjugated estrogens may cause a moderate interaction that could exacerbate diseases when taken with Ertugliflozin
Telmisartan (Compound) treats coronary artery disease (Disease) and coronary artery disease (Disease) is palliated by Isosorbide mononitrate (Compound) and Isosorbide mononitrate may cause a moderate interaction that could exacerbate diseases when taken with Ertugliflozin
Telmisartan (Compound) is included by Angiotensin 2 Receptor Antagonists (Pharmacologic Class) and Angiotensin 2 Receptor Antagonists (Pharmacologic Class) includes Eprosartan (Compound) and Eprosartan may cause a moderate interaction that could exacerbate diseases when taken with Ertugliflozin
Telmisartan (Compound) binds PPARG (Gene) and PPARG (Gene) is upregulated by Triamcinolone (Compound) and Triamcinolone may cause a moderate interaction that could exacerbate diseases when taken with Ertugliflozin