DDInter593 DDInter1181
Doxepin is a psychotropic agent with antidepressant and anxiolytic properties. It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to [cidoxepin]. Doxepin commonly produces a 5:1 (E):(Z) racemic mixture. In a strict sense, doxepin is not a tricyclic antidepressant but it is commonly associated with the class since it shares a lot of properties with members of the drug family including [amitriptyline], [clomipramine], [desipramine], [imipramine], [nortriptyline], [protriptyline] and [trimipramine]. Doxepin was developed by Pfizer and FDA approved in 1969 as an antidepressant. However, in 2010 it was approved for the treatment of insomnia. The latter
Mesuximide (or methsuximide) is an anticonvulsant medication. It is sold by Pfizer under the name Petinutin.
Doxepin {u} may lead to a major life threatening interaction when taken with {v} Meperidine
Meperidine {u} (Compound) resembles {v} (Compound) Methsuximide
Doxepin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenobarbital
Phenobarbital {u} (Compound) resembles {v} (Compound) Methsuximide
Doxepin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenytoin
Phenytoin {u} (Compound) resembles {v} (Compound) Methsuximide
Doxepin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clobazam
Clobazam {u} (Compound) resembles {v} (Compound) Methsuximide
Doxepin {u} (Compound) binds {v} (Gene) CYP2C19
CYP2C19 {u} (Gene) is bound by {v} (Compound) Methsuximide
Doxepin {u} (Compound) causes {v} (Side Effect) Somnolence
Somnolence {u} (Side Effect) is caused by {v} (Compound) Methsuximide
Doxepin {u} may lead to a major life threatening interaction when taken with {v} Meperidine
Meperidine {u} (Compound) resembles {v} (Compound) Glutethimide
Glutethimide {u} (Compound) resembles {v} (Compound) Methsuximide
Doxepin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenobarbital
Phenobarbital {u} (Compound) resembles {v} (Compound) Phenytoin
Phenytoin {u} (Compound) resembles {v} (Compound) Methsuximide
Doxepin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenytoin
Phenytoin {u} (Compound) resembles {v} (Compound) Phenobarbital
Phenobarbital {u} (Compound) resembles {v} (Compound) Methsuximide
Doxepin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clobazam
Clobazam {u} (Compound) resembles {v} (Compound) Ketazolam
Ketazolam {u} (Compound) resembles {v} (Compound) Methsuximide
Doxepin may lead to a major life threatening interaction when taken with Meperidine and Meperidine (Compound) resembles Methsuximide (Compound)
Doxepin may cause a moderate interaction that could exacerbate diseases when taken with Phenobarbital and Phenobarbital (Compound) resembles Methsuximide (Compound)
Doxepin may cause a moderate interaction that could exacerbate diseases when taken with Phenytoin and Phenytoin (Compound) resembles Methsuximide (Compound)
Doxepin may cause a moderate interaction that could exacerbate diseases when taken with Clobazam and Clobazam (Compound) resembles Methsuximide (Compound)
Doxepin (Compound) binds CYP2C19 (Gene) and CYP2C19 (Gene) is bound by Methsuximide (Compound)
Doxepin (Compound) causes Somnolence (Side Effect) and Somnolence (Side Effect) is caused by Methsuximide (Compound)
Doxepin may lead to a major life threatening interaction when taken with Meperidine and Meperidine (Compound) resembles Glutethimide (Compound) and Glutethimide (Compound) resembles Methsuximide (Compound)
Doxepin may cause a moderate interaction that could exacerbate diseases when taken with Phenobarbital and Phenobarbital (Compound) resembles Phenytoin (Compound) and Phenytoin (Compound) resembles Methsuximide (Compound)
Doxepin may cause a moderate interaction that could exacerbate diseases when taken with Phenytoin and Phenytoin (Compound) resembles Phenobarbital (Compound) and Phenobarbital (Compound) resembles Methsuximide (Compound)
Doxepin may cause a moderate interaction that could exacerbate diseases when taken with Clobazam and Clobazam (Compound) resembles Ketazolam (Compound) and Ketazolam (Compound) resembles Methsuximide (Compound)