DDInter676 DDInter119
Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome. It can also be found in quadruple regimens for the treatment of _H. pylori_ infections along with other antibiotics including,, and, for example.[A177271, F4498] Its efficacy is considered similar to other medications within the PPI class including,,,, and. Esomeprazole is the s-isomer of, which is a racemate of the S- and R-enantiomer. Esomeprazole has been shown to inhibit acid secretion to a similar extent as, without any significant differences between the two compounds _in vitro_. Esome
Armodafinil is the enantiopure of the wakefulness-promoting agent modafinil (Provigil), and is indicated to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea (OSA), narcolepsy, or shift work disorder (SWD). Research has shown that armodafinil significantly improves driving simulator performance in patients with SWD. Armodafinil consists of the (−)-R-enantiomer of the racemic modafinil. Armodafinil is produced by the pharmaceutical company Cephalon Inc. (a wholly owned subsidiary of Teva Pharmaceutical Industries Ltd.) and was approved by the U.S. Food and Drug Administration (FDA) in June 2007.
Esomeprazole {u} (Compound) resembles {v} (Compound) Lansoprazole
Esomeprazole {u} (Compound) resembles {v} (Compound) Omeprazole
Esomeprazole {u} (Compound) treats {v} (Disease) Barrett's esophagus
Esomeprazole {u} (Compound) binds {v} (Gene) ATP4A
Esomeprazole {u} (Compound) upregulates {v} (Gene) TIPARP
Esomeprazole {u} (Compound) palliates {v} (Disease) prostate cancer
Esomeprazole {u} (Compound) is included by {v} (Pharmacologic Class) Cytochrome P450 2C19 Inhibitors
Esomeprazole {u} (Compound) downregulates {v} (Gene) TRAPPC3
Esomeprazole {u} (Compound) causes {v} (Side Effect) Muscle spasms
Esomeprazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Choline salicylate
Esomeprazole (Compound) resembles Lansoprazole (Compound)
Esomeprazole (Compound) resembles Omeprazole (Compound)
Esomeprazole (Compound) treats Barrett's esophagus (Disease)
Esomeprazole (Compound) binds ATP4A (Gene)
Esomeprazole (Compound) upregulates TIPARP (Gene)
Esomeprazole (Compound) palliates prostate cancer (Disease)
Esomeprazole (Compound) is included by Cytochrome P450 2C19 Inhibitors (Pharmacologic Class)
Esomeprazole (Compound) downregulates TRAPPC3 (Gene)
Esomeprazole (Compound) causes Muscle spasms (Side Effect)
Esomeprazole may cause a minor interaction that can limit clinical effects when taken with Choline salicylate