DDInter1619 DDInter517
Ropinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label],. It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. In 2005, it was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome. In 2008, the extended-release capsules of ropinirole were approved, allowing for less frequent dosing, therefore increased compliance, and offering a similar side effect profile and efficacy to previous formulations of ropinirole.
Dexbrompheniramine maleate is an antihistamine agent that is used for the treatment of allergic conditions, such as hay fever or urticaria.
Ropinirole {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Carbinoxamine
Carbinoxamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dexbrompheniramine
Ropinirole {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Carbinoxamine
Carbinoxamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dexbrompheniramine
Ropinirole {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Bisacodyl
Bisacodyl {u} (Compound) resembles {v} (Compound) Dexbrompheniramine
Ropinirole {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Valproic acid
Valproic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dexbrompheniramine
Ropinirole {u} (Compound) causes {v} (Side Effect) Feeling abnormal
Feeling abnormal {u} (Side Effect) is caused by {v} (Compound) Valproic acid
Valproic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dexbrompheniramine
Ropinirole {u} (Compound) palliates {v} (Disease) Parkinson's disease
Parkinson's disease {u} (Disease) is palliated by {v} (Compound) Diphenhydramine
Diphenhydramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dexbrompheniramine
Ropinirole {u} (Compound) palliates {v} (Disease) Parkinson's disease
Parkinson's disease {u} (Disease) is palliated by {v} (Compound) Tolcapone
Tolcapone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dexbrompheniramine
Ropinirole {u} (Compound) binds {v} (Gene) DRD3
DRD3 {u} (Gene) is bound by {v} (Compound) Captodiame
Captodiame {u} (Compound) resembles {v} (Compound) Dexbrompheniramine
Ropinirole {u} (Compound) downregulates {v} (Gene) UBQLN2
UBQLN2 {u} (Gene) is upregulated by {v} (Compound) Chloropyramine
Chloropyramine {u} (Compound) resembles {v} (Compound) Dexbrompheniramine
Ropinirole {u} (Compound) upregulates {v} (Gene) RRP8
RRP8 {u} (Gene) is upregulated by {v} (Compound) Bisacodyl
Bisacodyl {u} (Compound) resembles {v} (Compound) Dexbrompheniramine
Ropinirole (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Carbinoxamine (Compound) and Carbinoxamine may cause a moderate interaction that could exacerbate diseases when taken with Dexbrompheniramine
Ropinirole (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Carbinoxamine (Compound) and Carbinoxamine may cause a moderate interaction that could exacerbate diseases when taken with Dexbrompheniramine
Ropinirole (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Bisacodyl (Compound) and Bisacodyl (Compound) resembles Dexbrompheniramine (Compound)
Ropinirole (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Valproic acid (Compound) and Valproic acid may cause a moderate interaction that could exacerbate diseases when taken with Dexbrompheniramine
Ropinirole (Compound) causes Feeling abnormal (Side Effect) and Feeling abnormal (Side Effect) is caused by Valproic acid (Compound) and Valproic acid may cause a moderate interaction that could exacerbate diseases when taken with Dexbrompheniramine
Ropinirole (Compound) palliates Parkinson's disease (Disease) and Parkinson's disease (Disease) is palliated by Diphenhydramine (Compound) and Diphenhydramine may cause a moderate interaction that could exacerbate diseases when taken with Dexbrompheniramine
Ropinirole (Compound) palliates Parkinson's disease (Disease) and Parkinson's disease (Disease) is palliated by Tolcapone (Compound) and Tolcapone may cause a moderate interaction that could exacerbate diseases when taken with Dexbrompheniramine
Ropinirole (Compound) binds DRD3 (Gene) and DRD3 (Gene) is bound by Captodiame (Compound) and Captodiame (Compound) resembles Dexbrompheniramine (Compound)
Ropinirole (Compound) downregulates UBQLN2 (Gene) and UBQLN2 (Gene) is upregulated by Chloropyramine (Compound) and Chloropyramine (Compound) resembles Dexbrompheniramine (Compound)
Ropinirole (Compound) upregulates RRP8 (Gene) and RRP8 (Gene) is upregulated by Bisacodyl (Compound) and Bisacodyl (Compound) resembles Dexbrompheniramine (Compound)