DDInter1253 DDInter125
Nabilone (marketed as Cesamet) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). Although structurally distinct from THC, nabilone mimics THC's structure and pharmacological activity through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, however it is considered to be twice as active as Δ⁹-THC. Nabilone is approved by the FDA for the treatment of nausea and vomiting associated with cancer chemotherapy in patients who have failed to respond adequately to conventional antiemetic treatments [FDA Label]. Tetrahydrocannabinol (THC) and cannabidiol (CBD) are the two most abundant cannabinoids found naturally in the resin of the marijuana plant, both of which are pharmacologically active due to their interaction with cannabinoid receptors that are
Developed by Schering-Plough after its merger with Organon International, asenapine is a sublingually administered, atypical antipsychotic for treatment of schizophrenia and acute mania associated with bipolar disorder. Asenapine also belongs to the dibenzo-oxepino pyrrole class. It is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use. FDA approved on August 13, 2009.
Nabilone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) Asenapine
Nabilone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amoxapine
Amoxapine {u} (Compound) resembles {v} (Compound) Asenapine
Nabilone {u} (Compound) causes {v} (Side Effect) Agitation
Agitation {u} (Side Effect) is caused by {v} (Compound) Asenapine
Nabilone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) Amoxapine
Amoxapine {u} (Compound) resembles {v} (Compound) Asenapine
Nabilone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amoxapine
Amoxapine {u} (Compound) resembles {v} (Compound) Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) Asenapine
Nabilone {u} (Compound) causes {v} (Side Effect) Agitation
Agitation {u} (Side Effect) is caused by {v} (Compound) Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) Asenapine
Nabilone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clobazam
Clobazam {u} (Compound) resembles {v} (Compound) Loxapine
Loxapine {u} (Compound) resembles {v} (Compound) Asenapine
Nabilone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Loxapine
Loxapine {u} (Compound) binds {v} (Gene) HRH2
HRH2 {u} (Gene) is bound by {v} (Compound) Asenapine
Nabilone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amoxapine
Amoxapine {u} (Compound) binds {v} (Gene) HRH1
HRH1 {u} (Gene) is bound by {v} (Compound) Asenapine
Nabilone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clobazam
Clobazam {u} (Compound) causes {v} (Side Effect) Agitation
Agitation {u} (Side Effect) is caused by {v} (Compound) Asenapine
Nabilone may cause a moderate interaction that could exacerbate diseases when taken with Loxapine and Loxapine (Compound) resembles Asenapine (Compound)
Nabilone may cause a moderate interaction that could exacerbate diseases when taken with Amoxapine and Amoxapine (Compound) resembles Asenapine (Compound)
Nabilone (Compound) causes Agitation (Side Effect) and Agitation (Side Effect) is caused by Asenapine (Compound)
Nabilone may cause a moderate interaction that could exacerbate diseases when taken with Loxapine and Loxapine (Compound) resembles Amoxapine (Compound) and Amoxapine (Compound) resembles Asenapine (Compound)
Nabilone may cause a moderate interaction that could exacerbate diseases when taken with Amoxapine and Amoxapine (Compound) resembles Loxapine (Compound) and Loxapine (Compound) resembles Asenapine (Compound)
Nabilone (Compound) causes Agitation (Side Effect) and Agitation (Side Effect) is caused by Loxapine (Compound) and Loxapine (Compound) resembles Asenapine (Compound)
Nabilone may cause a moderate interaction that could exacerbate diseases when taken with Clobazam and Clobazam (Compound) resembles Loxapine (Compound) and Loxapine (Compound) resembles Asenapine (Compound)
Nabilone may cause a moderate interaction that could exacerbate diseases when taken with Loxapine and Loxapine (Compound) binds HRH2 (Gene) and HRH2 (Gene) is bound by Asenapine (Compound)
Nabilone may cause a moderate interaction that could exacerbate diseases when taken with Amoxapine and Amoxapine (Compound) binds HRH1 (Gene) and HRH1 (Gene) is bound by Asenapine (Compound)
Nabilone may cause a moderate interaction that could exacerbate diseases when taken with Clobazam and Clobazam (Compound) causes Agitation (Side Effect) and Agitation (Side Effect) is caused by Asenapine (Compound)