DDInter1938 DDInter806
Vincristine is a vinca alkaloid with formula C46H56N4O10 found in the Madagascar periwinkle, Catharanthus roseus. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer. It has a role as a tubulin modulator, a microtubule-destabilising agent, a plant metabolite, an antineoplastic agent and a drug. It is a methyl ester, an acetate ester, a tertiary alcohol, a member of formamides, an organic heteropentacyclic compound, an organic heterotetracyclic compound, a tertiary amino compound and a vinca alkaloid. It is a conjugate base of a vincristine(2+). It derives from a hydride of a vincaleukoblastine.
An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Vincristine {u} (Compound) upregulates {v} (Gene) DHDDS
DHDDS {u} (Gene) is upregulated by {v} (Compound) Ganciclovir
Vincristine {u} (Compound) downregulates {v} (Gene) CDC25B
CDC25B {u} (Gene) is downregulated by {v} (Compound) Ganciclovir
Vincristine {u} (Compound) causes {v} (Side Effect) Connective tissue disorder
Connective tissue disorder {u} (Side Effect) is caused by {v} (Compound) Ganciclovir
Vincristine {u} (Compound) resembles {v} (Compound) Vinblastine
Vinblastine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ganciclovir
Vincristine {u} (Compound) resembles {v} (Compound) Vinorelbine
Vinorelbine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ganciclovir
Vincristine {u} (Compound) upregulates {v} (Gene) DHDDS
DHDDS {u} (Gene) is upregulated by {v} (Compound) Teniposide
Teniposide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ganciclovir
Vincristine {u} (Compound) downregulates {v} (Gene) CDC25B
CDC25B {u} (Gene) regulates {v} (Gene) CANT1
CANT1 {u} (Gene) is downregulated by {v} (Compound) Ganciclovir
Vincristine {u} (Compound) downregulates {v} (Gene) GDF15
GDF15 {u} (Gene) is downregulated by {v} (Compound) Leflunomide
Leflunomide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ganciclovir
Vincristine {u} (Compound) causes {v} (Side Effect) Connective tissue disorder
Connective tissue disorder {u} (Side Effect) is caused by {v} (Compound) Valganciclovir
Valganciclovir {u} (Compound) resembles {v} (Compound) Ganciclovir
Vincristine {u} (Compound) causes {v} (Side Effect) Convulsion
Convulsion {u} (Side Effect) is caused by {v} (Compound) Valaciclovir
Valaciclovir {u} (Compound) resembles {v} (Compound) Ganciclovir
Vincristine (Compound) upregulates DHDDS (Gene) and DHDDS (Gene) is upregulated by Ganciclovir (Compound)
Vincristine (Compound) downregulates CDC25B (Gene) and CDC25B (Gene) is downregulated by Ganciclovir (Compound)
Vincristine (Compound) causes Connective tissue disorder (Side Effect) and Connective tissue disorder (Side Effect) is caused by Ganciclovir (Compound)
Vincristine (Compound) resembles Vinblastine (Compound) and Vinblastine may cause a moderate interaction that could exacerbate diseases when taken with Ganciclovir
Vincristine (Compound) resembles Vinorelbine (Compound) and Vinorelbine may cause a moderate interaction that could exacerbate diseases when taken with Ganciclovir
Vincristine (Compound) upregulates DHDDS (Gene) and DHDDS (Gene) is upregulated by Teniposide (Compound) and Teniposide may cause a moderate interaction that could exacerbate diseases when taken with Ganciclovir
Vincristine (Compound) downregulates CDC25B (Gene) and CDC25B (Gene) regulates CANT1 (Gene) and CANT1 (Gene) is downregulated by Ganciclovir (Compound)
Vincristine (Compound) downregulates GDF15 (Gene) and GDF15 (Gene) is downregulated by Leflunomide (Compound) and Leflunomide may cause a moderate interaction that could exacerbate diseases when taken with Ganciclovir
Vincristine (Compound) causes Connective tissue disorder (Side Effect) and Connective tissue disorder (Side Effect) is caused by Valganciclovir (Compound) and Valganciclovir (Compound) resembles Ganciclovir (Compound)
Vincristine (Compound) causes Convulsion (Side Effect) and Convulsion (Side Effect) is caused by Valaciclovir (Compound) and Valaciclovir (Compound) resembles Ganciclovir (Compound)