DDInter981 DDInter1344
Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor. It is used in the treatment of major depression, dysthymic disorder, atypical disorder, panic disorder and the phobic disorders. It was first introduced by Roche pharmaceuticals, further developed by Validus pharms Inc and first FDA approved as a prescription drug on July 1st, 1959.
Opium is the first substance of the diverse group of the opiates. It has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years by the Sumerians. During the years, opium was used as a sedative and hypnotic, but it was determined to be addictive. Opium is extracted from _Papaver somniferum_, which is more known as poppies. This plant is an integrant of the Papaveraceae family, and it is characterized by solitary leaves and capsulated fruits. Therefore, opium is a sticky brown resin obtained by collecting and drying the latex that exudes from the poppy pods. Once extracted, opium contains two main groups of alkaloids; the psychoactive constituents which are in the category of phenanthrenes and alkaloids that have no central nervous system effect in the category of isoquinolines. Morphine is the most prevalent and principal alkaloid in opium, and it is responsible for most of the harmful effects of opium. Opium has gradually been superseded by a variety of synthetic opioids and general anesthetics. Some of the isolated derivatives of opium are morphine, noscapine, strychnine, veratrine, colchicine, codeine, and quinine. Opium is a prohibited drug of abuse in most countries, but the illegal production of this drug and its derivatives keeps being registered. There is some legal production of opium in different countries for the obtention of alkaloids by extraction.
Isocarboxazid {u} (Compound) resembles {v} (Compound) Phenacemide
Phenacemide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Isocarboxazid {u} (Compound) resembles {v} (Compound) Lacosamide
Lacosamide {u} (Compound) resembles {v} (Compound) Phenacemide
Phenacemide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Isocarboxazid {u} (Compound) resembles {v} (Compound) Phenacemide
Phenacemide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Carbinoxamine
Carbinoxamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Isocarboxazid {u} (Compound) resembles {v} (Compound) Benzyl alcohol
Benzyl alcohol {u} (Compound) resembles {v} (Compound) Selegiline
Selegiline {u} may lead to a major life threatening interaction when taken with {v} Opium
Isocarboxazid {u} (Compound) resembles {v} (Compound) Phenacemide
Phenacemide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mepyramine
Mepyramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Isocarboxazid {u} (Compound) resembles {v} (Compound) Metamfetamine
Metamfetamine {u} (Compound) resembles {v} (Compound) Phenacemide
Phenacemide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Isocarboxazid {u} (Compound) resembles {v} (Compound) Lacosamide
Lacosamide {u} (Compound) resembles {v} (Compound) Phenelzine
Phenelzine {u} may lead to a major life threatening interaction when taken with {v} Opium
Isocarboxazid {u} (Compound) resembles {v} (Compound) Bethanidine
Bethanidine {u} (Compound) resembles {v} (Compound) Selegiline
Selegiline {u} may lead to a major life threatening interaction when taken with {v} Opium
Isocarboxazid {u} (Compound) resembles {v} (Compound) Metamfetamine
Metamfetamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methdilazine
Methdilazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Isocarboxazid {u} (Compound) binds {v} (Gene) MAOB
MAOB {u} (Gene) is bound by {v} (Compound) Selegiline
Selegiline {u} may lead to a major life threatening interaction when taken with {v} Opium
Isocarboxazid (Compound) resembles Phenacemide (Compound) and Phenacemide may cause a moderate interaction that could exacerbate diseases when taken with Opium
Isocarboxazid (Compound) resembles Lacosamide (Compound) and Lacosamide (Compound) resembles Phenacemide (Compound) and Phenacemide may cause a moderate interaction that could exacerbate diseases when taken with Opium
Isocarboxazid (Compound) resembles Phenacemide (Compound) and Phenacemide may cause a moderate interaction that could exacerbate diseases when taken with Carbinoxamine and Carbinoxamine may cause a moderate interaction that could exacerbate diseases when taken with Opium
Isocarboxazid (Compound) resembles Benzyl alcohol (Compound) and Benzyl alcohol (Compound) resembles Selegiline (Compound) and Selegiline may lead to a major life threatening interaction when taken with Opium
Isocarboxazid (Compound) resembles Phenacemide (Compound) and Phenacemide may cause a moderate interaction that could exacerbate diseases when taken with Mepyramine and Mepyramine may cause a moderate interaction that could exacerbate diseases when taken with Opium
Isocarboxazid (Compound) resembles Metamfetamine (Compound) and Metamfetamine (Compound) resembles Phenacemide (Compound) and Phenacemide may cause a moderate interaction that could exacerbate diseases when taken with Opium
Isocarboxazid (Compound) resembles Lacosamide (Compound) and Lacosamide (Compound) resembles Phenelzine (Compound) and Phenelzine may lead to a major life threatening interaction when taken with Opium
Isocarboxazid (Compound) resembles Bethanidine (Compound) and Bethanidine (Compound) resembles Selegiline (Compound) and Selegiline may lead to a major life threatening interaction when taken with Opium
Isocarboxazid (Compound) resembles Metamfetamine (Compound) and Metamfetamine may cause a moderate interaction that could exacerbate diseases when taken with Methdilazine and Methdilazine may cause a moderate interaction that could exacerbate diseases when taken with Opium
Isocarboxazid (Compound) binds MAOB (Gene) and MAOB (Gene) is bound by Selegiline (Compound) and Selegiline may lead to a major life threatening interaction when taken with Opium