DDInter740 DDInter80
Flecainide is a Class I anti-arrhythmic agent like [encainide] and [propafenone]. Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter.[L8878,L5056] Flecainide was granted FDA approval on 31 October 1985.
Ammonium chloride is an inorganic compound with the formula NH4Cl. It is highly soluble in water producing mildly acidic solutions.
Flecainide {u} (Compound) binds {v} (Gene) SCN4A
SCN4A {u} (Gene) is bound by {v} (Compound) Mexiletine
Mexiletine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ammonium chloride
Flecainide {u} (Compound) causes {v} (Side Effect) Thrombocytopenia
Thrombocytopenia {u} (Side Effect) is caused by {v} (Compound) Mexiletine
Mexiletine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ammonium chloride
Flecainide {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Metamfetamine
Metamfetamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ammonium chloride
Flecainide {u} (Compound) causes {v} (Side Effect) Fatigue
Fatigue {u} (Side Effect) is caused by {v} (Compound) Lisdexamfetamine
Lisdexamfetamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ammonium chloride
Flecainide {u} (Compound) resembles {v} (Compound) Mefloquine
Mefloquine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mexiletine
Mexiletine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ammonium chloride
Flecainide {u} (Compound) resembles {v} (Compound) Mefloquine
Mefloquine {u} may lead to a major life threatening interaction when taken with {v} Methadone
Methadone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ammonium chloride
Flecainide {u} (Compound) resembles {v} (Compound) Mefloquine
Mefloquine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Protriptyline
Protriptyline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ammonium chloride
Flecainide {u} (Compound) resembles {v} (Compound) Mefloquine
Mefloquine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lisdexamfetamine
Lisdexamfetamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ammonium chloride
Flecainide {u} (Compound) upregulates {v} (Gene) DDIT4
DDIT4 {u} (Gene) is upregulated by {v} (Compound) Trimipramine
Trimipramine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ammonium chloride
Flecainide (Compound) binds SCN4A (Gene) and SCN4A (Gene) is bound by Mexiletine (Compound) and Mexiletine may cause a minor interaction that can limit clinical effects when taken with Ammonium chloride
Flecainide (Compound) causes Thrombocytopenia (Side Effect) and Thrombocytopenia (Side Effect) is caused by Mexiletine (Compound) and Mexiletine may cause a minor interaction that can limit clinical effects when taken with Ammonium chloride
Flecainide (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Metamfetamine (Compound) and Metamfetamine may cause a moderate interaction that could exacerbate diseases when taken with Ammonium chloride
Flecainide (Compound) causes Fatigue (Side Effect) and Fatigue (Side Effect) is caused by Lisdexamfetamine (Compound) and Lisdexamfetamine may cause a moderate interaction that could exacerbate diseases when taken with Ammonium chloride
Flecainide (Compound) resembles Mefloquine (Compound) and Mefloquine may cause a moderate interaction that could exacerbate diseases when taken with Mexiletine and Mexiletine may cause a minor interaction that can limit clinical effects when taken with Ammonium chloride
Flecainide (Compound) resembles Mefloquine (Compound) and Mefloquine may lead to a major life threatening interaction when taken with Methadone and Methadone may cause a minor interaction that can limit clinical effects when taken with Ammonium chloride
Flecainide (Compound) resembles Mefloquine (Compound) and Mefloquine may cause a moderate interaction that could exacerbate diseases when taken with Protriptyline and Protriptyline may cause a minor interaction that can limit clinical effects when taken with Ammonium chloride
Flecainide (Compound) resembles Mefloquine (Compound) and Mefloquine may cause a moderate interaction that could exacerbate diseases when taken with Lisdexamfetamine and Lisdexamfetamine may cause a moderate interaction that could exacerbate diseases when taken with Ammonium chloride
Flecainide (Compound) upregulates DDIT4 (Gene) and DDIT4 (Gene) is upregulated by Trimipramine (Compound) and Trimipramine may cause a minor interaction that can limit clinical effects when taken with Ammonium chloride