DDInter454 DDInter1180
Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from [Amitriptyline] by only a single double bond.[A185039,A184982] Since its approval, it has remained relatively popular as an adjunctive, short-term treatment for acute skeletal muscle spasms secondary to musculoskeletal injury.
Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Cyclobenzaprine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clofedanol
Cyclobenzaprine {u} (Compound) resembles {v} (Compound) Bromodiphenhydramine
Cyclobenzaprine {u} may lead to a major life threatening interaction when taken with {v} Doxepin
Cyclobenzaprine {u} (Compound) resembles {v} (Compound) Olopatadine
Cyclobenzaprine {u} (Compound) binds {v} (Gene) CYP1A2
Cyclobenzaprine {u} (Compound) palliates {v} (Disease) migraine
Cyclobenzaprine {u} (Compound) is included by {v} (Pharmacologic Class) Centrally-mediated Muscle Relaxation
Cyclobenzaprine {u} (Compound) causes {v} (Side Effect) Anxiety
Cyclobenzaprine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Azatadine
Cyclobenzaprine {u} may lead to a major life threatening interaction when taken with {v} Potassium chloride
Cyclobenzaprine may cause a moderate interaction that could exacerbate diseases when taken with Clofedanol
Cyclobenzaprine (Compound) resembles Bromodiphenhydramine (Compound)
Cyclobenzaprine may lead to a major life threatening interaction when taken with Doxepin
Cyclobenzaprine (Compound) resembles Olopatadine (Compound)
Cyclobenzaprine (Compound) binds CYP1A2 (Gene)
Cyclobenzaprine (Compound) palliates migraine (Disease)
Cyclobenzaprine (Compound) is included by Centrally-mediated Muscle Relaxation (Pharmacologic Class)
Cyclobenzaprine (Compound) causes Anxiety (Side Effect)
Cyclobenzaprine may cause a moderate interaction that could exacerbate diseases when taken with Azatadine
Cyclobenzaprine may lead to a major life threatening interaction when taken with Potassium chloride