DDInter1559 DDInter119
Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Armodafinil is the enantiopure of the wakefulness-promoting agent modafinil (Provigil), and is indicated to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea (OSA), narcolepsy, or shift work disorder (SWD). Research has shown that armodafinil significantly improves driving simulator performance in patients with SWD. Armodafinil consists of the (−)-R-enantiomer of the racemic modafinil. Armodafinil is produced by the pharmaceutical company Cephalon Inc. (a wholly owned subsidiary of Teva Pharmaceutical Industries Ltd.) and was approved by the U.S. Food and Drug Administration (FDA) in June 2007.
Rabeprazole {u} (Compound) resembles {v} (Compound) Lansoprazole
Rabeprazole {u} (Compound) resembles {v} (Compound) Esomeprazole
Rabeprazole {u} (Compound) binds {v} (Gene) CYP3A4
Rabeprazole {u} (Compound) downregulates {v} (Gene) THAP11
Rabeprazole {u} (Compound) causes {v} (Side Effect) Fungal skin infection
Rabeprazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Raltegravir
Rabeprazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Acetylsalicylic acid
Rabeprazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Riociguat
Rabeprazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indinavir
Rabeprazole {u} may lead to a major life threatening interaction when taken with {v} Neratinib
Rabeprazole (Compound) resembles Lansoprazole (Compound)
Rabeprazole (Compound) resembles Esomeprazole (Compound)
Rabeprazole (Compound) binds CYP3A4 (Gene)
Rabeprazole (Compound) downregulates THAP11 (Gene)
Rabeprazole (Compound) causes Fungal skin infection (Side Effect)
Rabeprazole may cause a minor interaction that can limit clinical effects when taken with Raltegravir
Rabeprazole may cause a minor interaction that can limit clinical effects when taken with Acetylsalicylic acid
Rabeprazole may cause a moderate interaction that could exacerbate diseases when taken with Riociguat
Rabeprazole may cause a moderate interaction that could exacerbate diseases when taken with Indinavir
Rabeprazole may lead to a major life threatening interaction when taken with Neratinib