DDInter856 DDInter312
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated hepar
Cefamandole is also known as cephamandole. It is a parenterally administered broad-spectrum cephalosporin antibiotic. It is generally formulated as a formate ester, [cefamandole nafate]. It is no longer marketed in the United States.
Cefamandole {u} (Compound) resembles {v} (Compound) Cefaclor
Cefamandole {u} (Compound) resembles {v} (Compound) Cefuroxime
Cefamandole {u} (Compound) binds {v} (Gene) SLC22A6
Cefamandole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mycophenolic acid
Cefamandole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Picosulfuric acid
Cefamandole (Compound) resembles Cefaclor (Compound)
Cefamandole (Compound) resembles Cefuroxime (Compound)
Cefamandole (Compound) binds SLC22A6 (Gene)
Cefamandole may cause a moderate interaction that could exacerbate diseases when taken with Mycophenolic acid
Cefamandole may cause a moderate interaction that could exacerbate diseases when taken with Picosulfuric acid