DDInter1791 DDInter1243
A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly for asthma, bronchospasm, and COPD.
An antiarrhythmia agent used primarily for ventricular rhythm disturbances.
Theophylline {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Methotrimeprazine
Methotrimeprazine {u} (Compound) resembles {v} (Compound) Moricizine
Theophylline {u} (Compound) causes {v} (Side Effect) Urinary retention
Urinary retention {u} (Side Effect) is caused by {v} (Compound) Methotrimeprazine
Methotrimeprazine {u} (Compound) resembles {v} (Compound) Moricizine
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Sucralfate
Sucralfate {u} may cause a minor interaction that can limit clinical effects when taken with {v} Methotrimeprazine
Methotrimeprazine {u} (Compound) resembles {v} (Compound) Moricizine
Theophylline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Picosulfuric acid
Picosulfuric acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methotrimeprazine
Methotrimeprazine {u} (Compound) resembles {v} (Compound) Moricizine
Theophylline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Terbinafine
Terbinafine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methotrimeprazine
Methotrimeprazine {u} (Compound) resembles {v} (Compound) Moricizine
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ephedrine
Ephedrine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methotrimeprazine
Methotrimeprazine {u} (Compound) resembles {v} (Compound) Moricizine
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ephedrine
Ephedrine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Doxapram
Doxapram {u} (Compound) resembles {v} (Compound) Moricizine
Theophylline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Osilodrostat
Osilodrostat {u} may lead to a major life threatening interaction when taken with {v} Thioridazine
Thioridazine {u} (Compound) resembles {v} (Compound) Moricizine
Theophylline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cetirizine
Cetirizine {u} (Compound) resembles {v} (Compound) Prochlorperazine
Prochlorperazine {u} (Compound) resembles {v} (Compound) Moricizine
Theophylline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Terbinafine
Terbinafine {u} (Compound) downregulates {v} (Gene) OXA1L
OXA1L {u} (Gene) is downregulated by {v} (Compound) Moricizine
Theophylline (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Methotrimeprazine (Compound) and Methotrimeprazine (Compound) resembles Moricizine (Compound)
Theophylline (Compound) causes Urinary retention (Side Effect) and Urinary retention (Side Effect) is caused by Methotrimeprazine (Compound) and Methotrimeprazine (Compound) resembles Moricizine (Compound)
Theophylline may cause a minor interaction that can limit clinical effects when taken with Sucralfate and Sucralfate may cause a minor interaction that can limit clinical effects when taken with Methotrimeprazine and Methotrimeprazine (Compound) resembles Moricizine (Compound)
Theophylline may cause a moderate interaction that could exacerbate diseases when taken with Picosulfuric acid and Picosulfuric acid may cause a moderate interaction that could exacerbate diseases when taken with Methotrimeprazine and Methotrimeprazine (Compound) resembles Moricizine (Compound)
Theophylline may cause a moderate interaction that could exacerbate diseases when taken with Terbinafine and Terbinafine may cause a moderate interaction that could exacerbate diseases when taken with Methotrimeprazine and Methotrimeprazine (Compound) resembles Moricizine (Compound)
Theophylline may cause a minor interaction that can limit clinical effects when taken with Ephedrine and Ephedrine may cause a moderate interaction that could exacerbate diseases when taken with Methotrimeprazine and Methotrimeprazine (Compound) resembles Moricizine (Compound)
Theophylline may cause a minor interaction that can limit clinical effects when taken with Ephedrine and Ephedrine may cause a moderate interaction that could exacerbate diseases when taken with Doxapram and Doxapram (Compound) resembles Moricizine (Compound)
Theophylline may cause a moderate interaction that could exacerbate diseases when taken with Osilodrostat and Osilodrostat may lead to a major life threatening interaction when taken with Thioridazine and Thioridazine (Compound) resembles Moricizine (Compound)
Theophylline may cause a minor interaction that can limit clinical effects when taken with Cetirizine and Cetirizine (Compound) resembles Prochlorperazine (Compound) and Prochlorperazine (Compound) resembles Moricizine (Compound)
Theophylline may cause a moderate interaction that could exacerbate diseases when taken with Terbinafine and Terbinafine (Compound) downregulates OXA1L (Gene) and OXA1L (Gene) is downregulated by Moricizine (Compound)