DDInter336 DDInter958
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in the colon. It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval in 1998. Interestingly, selective COX-2 inhibitors (especially celecoxib), have been evaluated as potential cancer chemopreventive and therapeutic drugs in clinical trials for a variety of malignancies.
Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents.
Celecoxib {u} (Compound) causes {v} (Side Effect) Vertigo
Vertigo {u} (Side Effect) is caused by {v} (Compound) Iodixanol
Celecoxib {u} (Compound) causes {v} (Side Effect) Vertigo
Vertigo {u} (Side Effect) is caused by {v} (Compound) Polythiazide
Polythiazide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iodixanol
Celecoxib {u} (Compound) causes {v} (Side Effect) Dyspepsia
Dyspepsia {u} (Side Effect) is caused by {v} (Compound) Diclofenamide
Diclofenamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iodixanol
Celecoxib {u} (Compound) causes {v} (Side Effect) Syncope
Syncope {u} (Side Effect) is caused by {v} (Compound) Iohexol
Iohexol {u} (Compound) resembles {v} (Compound) Iodixanol
Celecoxib {u} (Compound) causes {v} (Side Effect) Epilepsy
Epilepsy {u} (Side Effect) is caused by {v} (Compound) Pamidronic acid
Pamidronic acid {u} may lead to a major life threatening interaction when taken with {v} Iodixanol
Celecoxib {u} (Compound) causes {v} (Side Effect) Haematoma
Haematoma {u} (Side Effect) is caused by {v} (Compound) Iobenguane
Iobenguane {u} may lead to a major life threatening interaction when taken with {v} Iodixanol
Celecoxib {u} (Compound) palliates {v} (Disease) systemic scleroderma
systemic scleroderma {u} (Disease) downregulates {v} (Gene) XBP1
XBP1 {u} (Gene) is upregulated by {v} (Compound) Iodixanol
Celecoxib {u} (Compound) upregulates {v} (Gene) ST3GAL5
ST3GAL5 {u} (Gene) is regulated by {v} (Gene) XBP1
XBP1 {u} (Gene) is upregulated by {v} (Compound) Iodixanol
Celecoxib {u} (Compound) palliates {v} (Disease) systemic scleroderma
systemic scleroderma {u} (Disease) is palliated by {v} (Compound) Meloxicam
Meloxicam {u} may lead to a major life threatening interaction when taken with {v} Iodixanol
Celecoxib {u} (Compound) downregulates {v} (Gene) ZMIZ1
ZMIZ1 {u} (Gene) regulates {v} (Gene) XBP1
XBP1 {u} (Gene) is upregulated by {v} (Compound) Iodixanol
Celecoxib (Compound) causes Vertigo (Side Effect) and Vertigo (Side Effect) is caused by Iodixanol (Compound)
Celecoxib (Compound) causes Vertigo (Side Effect) and Vertigo (Side Effect) is caused by Polythiazide (Compound) and Polythiazide may cause a moderate interaction that could exacerbate diseases when taken with Iodixanol
Celecoxib (Compound) causes Dyspepsia (Side Effect) and Dyspepsia (Side Effect) is caused by Diclofenamide (Compound) and Diclofenamide may cause a moderate interaction that could exacerbate diseases when taken with Iodixanol
Celecoxib (Compound) causes Syncope (Side Effect) and Syncope (Side Effect) is caused by Iohexol (Compound) and Iohexol (Compound) resembles Iodixanol (Compound)
Celecoxib (Compound) causes Epilepsy (Side Effect) and Epilepsy (Side Effect) is caused by Pamidronic acid (Compound) and Pamidronic acid may lead to a major life threatening interaction when taken with Iodixanol
Celecoxib (Compound) causes Haematoma (Side Effect) and Haematoma (Side Effect) is caused by Iobenguane (Compound) and Iobenguane may lead to a major life threatening interaction when taken with Iodixanol
Celecoxib (Compound) palliates systemic scleroderma (Disease) and systemic scleroderma (Disease) downregulates XBP1 (Gene) and XBP1 (Gene) is upregulated by Iodixanol (Compound)
Celecoxib (Compound) upregulates ST3GAL5 (Gene) and ST3GAL5 (Gene) is regulated by XBP1 (Gene) and XBP1 (Gene) is upregulated by Iodixanol (Compound)
Celecoxib (Compound) palliates systemic scleroderma (Disease) and systemic scleroderma (Disease) is palliated by Meloxicam (Compound) and Meloxicam may lead to a major life threatening interaction when taken with Iodixanol
Celecoxib (Compound) downregulates ZMIZ1 (Gene) and ZMIZ1 (Gene) regulates XBP1 (Gene) and XBP1 (Gene) is upregulated by Iodixanol (Compound)