DDInter1609 DDInter1763
Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food. FDA approved on July 1, 2011.
Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). It was developed by Wyeth Pharmaceuticals under the trade name Torisel. Temsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007.
Rivaroxaban {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Temsirolimus
Rivaroxaban {u} (Compound) causes {v} (Side Effect) Ecchymosis
Ecchymosis {u} (Side Effect) is caused by {v} (Compound) Temsirolimus
Rivaroxaban {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Everolimus
Everolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Rivaroxaban {u} (Compound) causes {v} (Side Effect) Ecchymosis
Ecchymosis {u} (Side Effect) is caused by {v} (Compound) Tacrolimus
Tacrolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Rivaroxaban {u} (Compound) resembles {v} (Compound) Linezolid
Linezolid {u} (Compound) causes {v} (Side Effect) Thrombophlebitis
Thrombophlebitis {u} (Side Effect) is caused by {v} (Compound) Temsirolimus
Rivaroxaban {u} (Compound) binds {v} (Gene) F10
F10 {u} (Gene) regulates {v} (Gene) NIT1
NIT1 {u} (Gene) is upregulated by {v} (Compound) Temsirolimus
Rivaroxaban {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is downregulated by {v} (Disease) and {u} (Disease) associated with {v} (Gene) kidney cancer
kidney cancer {u} (Disease) is treated by {v} (Compound) Temsirolimus
Rivaroxaban {u} (Compound) binds {v} (Gene) CYP2J2
CYP2J2 {u} (Gene) is upregulated by {v} (Disease) kidney cancer
kidney cancer {u} (Disease) is treated by {v} (Compound) Temsirolimus
Rivaroxaban {u} (Compound) upregulates {v} (Gene) CDK6
CDK6 {u} (Gene) interacts with {v} (Gene) EZH2
EZH2 {u} (Gene) is downregulated by {v} (Compound) Temsirolimus
Rivaroxaban {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) interacts with {v} (Gene) STUB1
STUB1 {u} (Gene) is downregulated by {v} (Compound) Temsirolimus
Rivaroxaban (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Temsirolimus (Compound)
Rivaroxaban (Compound) causes Ecchymosis (Side Effect) and Ecchymosis (Side Effect) is caused by Temsirolimus (Compound)
Rivaroxaban (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Everolimus (Compound) and Everolimus (Compound) resembles Temsirolimus (Compound)
Rivaroxaban (Compound) causes Ecchymosis (Side Effect) and Ecchymosis (Side Effect) is caused by Tacrolimus (Compound) and Tacrolimus (Compound) resembles Temsirolimus (Compound)
Rivaroxaban (Compound) resembles Linezolid (Compound) and Linezolid (Compound) causes Thrombophlebitis (Side Effect) and Thrombophlebitis (Side Effect) is caused by Temsirolimus (Compound)
Rivaroxaban (Compound) binds F10 (Gene) and F10 (Gene) regulates NIT1 (Gene) and NIT1 (Gene) is upregulated by Temsirolimus (Compound)
Rivaroxaban (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is downregulated by kidney cancer (Disease) and ABCB1 (Disease) associated with kidney cancer (Gene) and kidney cancer (Disease) is treated by Temsirolimus (Compound)
Rivaroxaban (Compound) binds CYP2J2 (Gene) and CYP2J2 (Gene) is upregulated by kidney cancer (Disease) and kidney cancer (Disease) is treated by Temsirolimus (Compound)
Rivaroxaban (Compound) upregulates CDK6 (Gene) and CDK6 (Gene) interacts with EZH2 (Gene) and EZH2 (Gene) is downregulated by Temsirolimus (Compound)
Rivaroxaban (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) interacts with STUB1 (Gene) and STUB1 (Gene) is downregulated by Temsirolimus (Compound)