DDInter1867 DDInter1197
A phenothiazine used as an antipsychotic agent and as an antiemetic.
Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to gastroesophageal reflux disease (GERD). It can also be used to prevent nausea or vomiting associated with chemotherapy or certain surgical or diagnostic procedures. One unique property of this drug is that it does not increase gastric acid secretion. It is available in the oral tablet form or in solution, and can also be administered through the intravenous route. Metoclopramide was initially approved by the FDA in 1980.
Triflupromazine {u} (Compound) binds {v} (Gene) CHRM1
CHRM1 {u} (Gene) is bound by {v} (Compound) Metoclopramide
Triflupromazine {u} (Compound) resembles {v} (Compound) Clomipramine
Clomipramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Metoclopramide
Triflupromazine {u} (Compound) resembles {v} (Compound) Perphenazine
Perphenazine {u} may lead to a major life threatening interaction when taken with {v} Metoclopramide
Triflupromazine {u} (Compound) resembles {v} (Compound) Methotrimeprazine
Methotrimeprazine {u} may lead to a major life threatening interaction when taken with {v} Metoclopramide
Triflupromazine {u} (Compound) binds {v} (Gene) CHRM1
CHRM1 {u} (Gene) is bound by {v} (Compound) Benzatropine
Benzatropine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Metoclopramide
Triflupromazine {u} (Compound) binds {v} (Gene) DRD2
DRD2 {u} (Gene) is bound by {v} (Compound) Cisapride
Cisapride {u} (Compound) resembles {v} (Compound) Metoclopramide
Triflupromazine {u} (Compound) resembles {v} (Compound) Clomipramine
Clomipramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sunitinib
Sunitinib {u} (Compound) resembles {v} (Compound) Metoclopramide
Triflupromazine {u} (Compound) resembles {v} (Compound) Thioridazine
Thioridazine {u} may lead to a major life threatening interaction when taken with {v} Sunitinib
Sunitinib {u} (Compound) resembles {v} (Compound) Metoclopramide
Triflupromazine {u} (Compound) resembles {v} (Compound) Methdilazine
Methdilazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dopamine
Dopamine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metoclopramide
Triflupromazine {u} (Compound) resembles {v} (Compound) Propiomazine
Propiomazine {u} (Compound) binds {v} (Gene) CHRM1
CHRM1 {u} (Gene) is bound by {v} (Compound) Metoclopramide
Triflupromazine (Compound) binds CHRM1 (Gene) and CHRM1 (Gene) is bound by Metoclopramide (Compound)
Triflupromazine (Compound) resembles Clomipramine (Compound) and Clomipramine may cause a moderate interaction that could exacerbate diseases when taken with Metoclopramide
Triflupromazine (Compound) resembles Perphenazine (Compound) and Perphenazine may lead to a major life threatening interaction when taken with Metoclopramide
Triflupromazine (Compound) resembles Methotrimeprazine (Compound) and Methotrimeprazine may lead to a major life threatening interaction when taken with Metoclopramide
Triflupromazine (Compound) binds CHRM1 (Gene) and CHRM1 (Gene) is bound by Benzatropine (Compound) and Benzatropine may cause a moderate interaction that could exacerbate diseases when taken with Metoclopramide
Triflupromazine (Compound) binds DRD2 (Gene) and DRD2 (Gene) is bound by Cisapride (Compound) and Cisapride (Compound) resembles Metoclopramide (Compound)
Triflupromazine (Compound) resembles Clomipramine (Compound) and Clomipramine may cause a moderate interaction that could exacerbate diseases when taken with Sunitinib and Sunitinib (Compound) resembles Metoclopramide (Compound)
Triflupromazine (Compound) resembles Thioridazine (Compound) and Thioridazine may lead to a major life threatening interaction when taken with Sunitinib and Sunitinib (Compound) resembles Metoclopramide (Compound)
Triflupromazine (Compound) resembles Methdilazine (Compound) and Methdilazine may cause a moderate interaction that could exacerbate diseases when taken with Dopamine and Dopamine may cause a minor interaction that can limit clinical effects when taken with Metoclopramide
Triflupromazine (Compound) resembles Propiomazine (Compound) and Propiomazine (Compound) binds CHRM1 (Gene) and CHRM1 (Gene) is bound by Metoclopramide (Compound)