DDInter775 DDInter721
Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they are cleaved into monomeric units. The monomeric sequence in heparin and HS is thought to form the high affinity binding site for the natural anti-coagulant factor, antithrombin III (ATIII). Once bound to heparin or HS, the anticoagulant activity of ATIII is potentiated by 1000-fold. Fondaparinux potentiates the neutralizing action of ATIII on activated Factor X 300-fold. Fondaparinux may be used: to prevent venous thromboembolism in patients who have undergone orthopedic surgery of the lower limbs (e.g. hip fracture
An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Fondaparinux {u} may lead to a major life threatening interaction when taken with {v} Flurbiprofen
Flurbiprofen {u} (Compound) resembles {v} (Compound) Fenoprofen
Fondaparinux {u} (Compound) causes {v} (Side Effect) Dyspepsia
Dyspepsia {u} (Side Effect) is caused by {v} (Compound) Fenoprofen
Fondaparinux {u} may lead to a major life threatening interaction when taken with {v} Flurbiprofen
Flurbiprofen {u} (Compound) resembles {v} (Compound) Fenbufen
Fenbufen {u} (Compound) resembles {v} (Compound) Fenoprofen
Fondaparinux {u} may lead to a major life threatening interaction when taken with {v} Ibuprofen
Ibuprofen {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Labetalol
Labetalol {u} (Compound) resembles {v} (Compound) Fenoprofen
Fondaparinux {u} may lead to a major life threatening interaction when taken with {v} Warfarin
Warfarin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Labetalol
Labetalol {u} (Compound) resembles {v} (Compound) Fenoprofen
Fondaparinux {u} (Compound) causes {v} (Side Effect) Dyspepsia
Dyspepsia {u} (Side Effect) is caused by {v} (Compound) Labetalol
Labetalol {u} (Compound) resembles {v} (Compound) Fenoprofen
Fondaparinux {u} may lead to a major life threatening interaction when taken with {v} Ketorolac
Ketorolac {u} (Compound) resembles {v} (Compound) Fenbufen
Fenbufen {u} (Compound) resembles {v} (Compound) Fenoprofen
Fondaparinux {u} may lead to a major life threatening interaction when taken with {v} Ibuprofen
Ibuprofen {u} (Compound) resembles {v} (Compound) Naproxen
Naproxen {u} (Compound) resembles {v} (Compound) Fenoprofen
Fondaparinux {u} may lead to a major life threatening interaction when taken with {v} Ketorolac
Ketorolac {u} may lead to a major life threatening interaction when taken with {v} Flurbiprofen
Flurbiprofen {u} (Compound) resembles {v} (Compound) Fenoprofen
Fondaparinux {u} may lead to a major life threatening interaction when taken with {v} Ibuprofen
Ibuprofen {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Flurbiprofen
Flurbiprofen {u} (Compound) resembles {v} (Compound) Fenoprofen
Fondaparinux may lead to a major life threatening interaction when taken with Flurbiprofen and Flurbiprofen (Compound) resembles Fenoprofen (Compound)
Fondaparinux (Compound) causes Dyspepsia (Side Effect) and Dyspepsia (Side Effect) is caused by Fenoprofen (Compound)
Fondaparinux may lead to a major life threatening interaction when taken with Flurbiprofen and Flurbiprofen (Compound) resembles Fenbufen (Compound) and Fenbufen (Compound) resembles Fenoprofen (Compound)
Fondaparinux may lead to a major life threatening interaction when taken with Ibuprofen and Ibuprofen may cause a moderate interaction that could exacerbate diseases when taken with Labetalol and Labetalol (Compound) resembles Fenoprofen (Compound)
Fondaparinux may lead to a major life threatening interaction when taken with Warfarin and Warfarin may cause a minor interaction that can limit clinical effects when taken with Labetalol and Labetalol (Compound) resembles Fenoprofen (Compound)
Fondaparinux (Compound) causes Dyspepsia (Side Effect) and Dyspepsia (Side Effect) is caused by Labetalol (Compound) and Labetalol (Compound) resembles Fenoprofen (Compound)
Fondaparinux may lead to a major life threatening interaction when taken with Ketorolac and Ketorolac (Compound) resembles Fenbufen (Compound) and Fenbufen (Compound) resembles Fenoprofen (Compound)
Fondaparinux may lead to a major life threatening interaction when taken with Ibuprofen and Ibuprofen (Compound) resembles Naproxen (Compound) and Naproxen (Compound) resembles Fenoprofen (Compound)
Fondaparinux may lead to a major life threatening interaction when taken with Ketorolac and Ketorolac may lead to a major life threatening interaction when taken with Flurbiprofen and Flurbiprofen (Compound) resembles Fenoprofen (Compound)
Fondaparinux may lead to a major life threatening interaction when taken with Ibuprofen and Ibuprofen (Compound) resembles Flurbiprofen (Compound) and Ibuprofen may cause a moderate interaction that could exacerbate diseases when taken with Flurbiprofen and Flurbiprofen (Compound) resembles Fenoprofen (Compound)