DDInter1879 DDInter1747
First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of cough and cold medicines. It may cause drowsiness.
Tasimelteon is a selective dual melatonin receptor agonist indicated for the treatment of Non-24-Hour Sleep-Wake Disorder (N24HSWD). Occurring commonly in blind individuals without light perception, this condition is often characterized by periods of night-time insomnia and day-time sleepiness. In blind individuals, a lack of light stimulation causes an extension of the 24-hour circadian cycle and can lead to progressively delayed sleep onset. By activating melatonin receptors MT1 and MT2 in the suprachiasmatic nucleus of the brain, tasimelteon has been shown to improve sleep by resynchronizing the circadian rhythm through its "non-photic" mechanism. Tasimelteon is currently the only drug available for the treatment of N24HSWD and was granted orphan drug status by the FDA in 2010.
Triprolidine {u} (Compound) resembles {v} (Compound) Eperisone
Triprolidine {u} (Compound) resembles {v} (Compound) Cloperastine
Triprolidine {u} (Compound) binds {v} (Gene) CYP2D6
Triprolidine {u} (Compound) upregulates {v} (Gene) NFKBIA
Triprolidine {u} (Compound) palliates {v} (Disease) atopic dermatitis
Triprolidine {u} (Compound) downregulates {v} (Gene) RAP1GAP
Triprolidine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Hyaluronidase
Triprolidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxazepam
Triprolidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Secobarbital
Triprolidine {u} may lead to a major life threatening interaction when taken with {v} Zonisamide
Triprolidine (Compound) resembles Eperisone (Compound)
Triprolidine (Compound) resembles Cloperastine (Compound)
Triprolidine (Compound) binds CYP2D6 (Gene)
Triprolidine (Compound) upregulates NFKBIA (Gene)
Triprolidine (Compound) palliates atopic dermatitis (Disease)
Triprolidine (Compound) downregulates RAP1GAP (Gene)
Triprolidine may cause a minor interaction that can limit clinical effects when taken with Hyaluronidase
Triprolidine may cause a moderate interaction that could exacerbate diseases when taken with Oxazepam
Triprolidine may cause a moderate interaction that could exacerbate diseases when taken with Secobarbital
Triprolidine may lead to a major life threatening interaction when taken with Zonisamide