DDInter49 DDInter1376
Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that cause pain, nausea, and other symptoms of migraine. Almotriptan does not prevent migraine attacks.
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26, 2020.[L12573,L12582] The US approval was followed by the approval in Canada on October 2, 2020. In November 2021, ozanimod was also approved by the European Commission for the treatment of adults with relapsing remitting multiple sclerosis.[L39377,L39382] MS is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Inflammatory bowel disease also a chronic inflammatory condition and can cause persistent abdominal pain, diarrhea, bloody stools, and vomiting. In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard in MS therapy. Studies involving patients with inflammatory bowel disease have also shown promising results.[A189318,A189342]
Almotriptan {u} (Compound) resembles {v} (Compound) Eletriptan
Almotriptan {u} (Compound) resembles {v} (Compound) Naratriptan
Almotriptan {u} (Compound) binds {v} (Gene) CYP2C19
Almotriptan {u} (Compound) palliates {v} (Disease) migraine
Almotriptan {u} (Compound) is included by {v} (Pharmacologic Class) Serotonin 1b Receptor Agonists
Almotriptan {u} (Compound) causes {v} (Side Effect) Peripheral coldness
Almotriptan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dasatinib
Almotriptan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Morphine
Almotriptan {u} may lead to a major life threatening interaction when taken with {v} Palonosetron
Almotriptan {u} may lead to a major life threatening interaction when taken with {v} Methylene blue
Almotriptan (Compound) resembles Eletriptan (Compound)
Almotriptan (Compound) resembles Naratriptan (Compound)
Almotriptan (Compound) binds CYP2C19 (Gene)
Almotriptan (Compound) palliates migraine (Disease)
Almotriptan (Compound) is included by Serotonin 1b Receptor Agonists (Pharmacologic Class)
Almotriptan (Compound) causes Peripheral coldness (Side Effect)
Almotriptan may cause a moderate interaction that could exacerbate diseases when taken with Dasatinib
Almotriptan may cause a moderate interaction that could exacerbate diseases when taken with Morphine
Almotriptan may lead to a major life threatening interaction when taken with Palonosetron
Almotriptan may lead to a major life threatening interaction when taken with Methylene blue