DDInter292 DDInter832
Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension.
A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Captopril {u} (Compound) resembles {v} (Compound) Enalapril
Captopril {u} (Compound) treats {v} (Disease) coronary artery disease
Captopril {u} (Compound) binds {v} (Gene) MMP2
Captopril {u} (Compound) upregulates {v} (Gene) RELB
Captopril {u} (Compound) downregulates {v} (Gene) NPC1
Captopril {u} (Compound) causes {v} (Side Effect) Diabetic
Captopril {u} may cause a minor interaction that can limit clinical effects when taken with {v} Sodium citrate
Captopril {u} may cause a minor interaction that can limit clinical effects when taken with {v} Darbepoetin alfa
Captopril {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Insulin lispro
Captopril {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Insulin glulisine
Captopril (Compound) resembles Enalapril (Compound)
Captopril (Compound) treats coronary artery disease (Disease)
Captopril (Compound) binds MMP2 (Gene)
Captopril (Compound) upregulates RELB (Gene)
Captopril (Compound) downregulates NPC1 (Gene)
Captopril (Compound) causes Diabetic (Side Effect)
Captopril may cause a minor interaction that can limit clinical effects when taken with Sodium citrate
Captopril may cause a minor interaction that can limit clinical effects when taken with Darbepoetin alfa
Captopril may cause a moderate interaction that could exacerbate diseases when taken with Insulin lispro
Captopril may cause a moderate interaction that could exacerbate diseases when taken with Insulin glulisine