DDInter188 DDInter1082
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.
Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM). It is sold by Sanofi-Aventis under the brand name Adlyxin in the US and Lyxumia in the EU. Adlyxin recieved FDA approval July 28, 2016.
Benzthiazide {u} (Compound) resembles {v} (Compound) Metolazone
Benzthiazide {u} (Compound) resembles {v} (Compound) Trichlormethiazide
Benzthiazide {u} (Compound) binds {v} (Gene) CA1
Benzthiazide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Glycopyrronium
Benzthiazide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Trospium
Benzthiazide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Betamethasone
Benzthiazide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tolbutamide
Benzthiazide {u} may lead to a major life threatening interaction when taken with {v} Dolasetron
Benzthiazide (Compound) resembles Metolazone (Compound)
Benzthiazide (Compound) resembles Trichlormethiazide (Compound)
Benzthiazide (Compound) binds CA1 (Gene)
Benzthiazide may cause a minor interaction that can limit clinical effects when taken with Glycopyrronium
Benzthiazide may cause a minor interaction that can limit clinical effects when taken with Trospium
Benzthiazide may cause a moderate interaction that could exacerbate diseases when taken with Betamethasone
Benzthiazide may cause a moderate interaction that could exacerbate diseases when taken with Tolbutamide
Benzthiazide may lead to a major life threatening interaction when taken with Dolasetron