DDInter1465 DDInter1180
A naturally occurring alkaloid derived from the _Pilocarpus_ plants, pilocarpine is a muscarinic acetylcholine agonist.[A262016, A262036] Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated intraocular pressure and glaucoma. The usage of glaucoma by pilocarpine dates back to 1875.
Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Pilocarpine {u} (Compound) treats {v} (Disease) glaucoma
Pilocarpine {u} (Compound) binds {v} (Gene) CHRM1
Pilocarpine {u} (Compound) upregulates {v} (Gene) PRKX
Pilocarpine {u} (Compound) palliates {v} (Disease) head and neck cancer
Pilocarpine {u} (Compound) is included by {v} (Pharmacologic Class) Cholinergic Muscarinic Agonists
Pilocarpine {u} (Compound) downregulates {v} (Gene) DLD
Pilocarpine {u} (Compound) causes {v} (Side Effect) Eye disorder
Pilocarpine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dicyclomine
Pilocarpine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Aclidinium
Pilocarpine (Compound) treats glaucoma (Disease)
Pilocarpine (Compound) binds CHRM1 (Gene)
Pilocarpine (Compound) upregulates PRKX (Gene)
Pilocarpine (Compound) palliates head and neck cancer (Disease)
Pilocarpine (Compound) is included by Cholinergic Muscarinic Agonists (Pharmacologic Class)
Pilocarpine (Compound) downregulates DLD (Gene)
Pilocarpine (Compound) causes Eye disorder (Side Effect)
Pilocarpine may cause a moderate interaction that could exacerbate diseases when taken with Dicyclomine
Pilocarpine may cause a moderate interaction that could exacerbate diseases when taken with Aclidinium