DDInter458 DDInter1193
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus _Beauveria nivea_. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methyltestosterone is a schedule III drug in the US.
Cyclosporine {u} (Compound) binds {v} (Gene) SLCO1A2
SLCO1A2 {u} (Gene) is bound by {v} (Compound) Methyltestosterone
Cyclosporine {u} (Compound) upregulates {v} (Gene) EDEM1
EDEM1 {u} (Gene) is upregulated by {v} (Compound) Methyltestosterone
Cyclosporine {u} (Compound) downregulates {v} (Gene) CCDC85B
CCDC85B {u} (Gene) is downregulated by {v} (Compound) Methyltestosterone
Cyclosporine {u} (Compound) upregulates {v} (Gene) DHRS7
DHRS7 {u} (Gene) is downregulated by {v} (Compound) Methyltestosterone
Cyclosporine {u} (Compound) causes {v} (Side Effect) Libido decreased
Libido decreased {u} (Side Effect) is caused by {v} (Compound) Methyltestosterone
Cyclosporine {u} (Compound) binds {v} (Gene) SLCO1A2
SLCO1A2 {u} (Gene) is bound by {v} (Compound) Spironolactone
Spironolactone {u} (Compound) resembles {v} (Compound) Methyltestosterone
Cyclosporine {u} (Compound) upregulates {v} (Gene) EDEM1
EDEM1 {u} (Gene) is upregulated by {v} (Compound) Testosterone Propionate
Testosterone Propionate {u} (Compound) resembles {v} (Compound) Methyltestosterone
Cyclosporine {u} (Compound) upregulates {v} (Gene) FOXO3
FOXO3 {u} (Gene) is upregulated by {v} (Compound) Danazol
Danazol {u} (Compound) resembles {v} (Compound) Methyltestosterone
Cyclosporine {u} (Compound) downregulates {v} (Gene) CCDC85B
CCDC85B {u} (Gene) is downregulated by {v} (Compound) Testosterone Propionate
Testosterone Propionate {u} (Compound) resembles {v} (Compound) Methyltestosterone
Cyclosporine {u} (Compound) upregulates {v} (Gene) DHRS7
DHRS7 {u} (Gene) is downregulated by {v} (Compound) Levonorgestrel
Levonorgestrel {u} (Compound) resembles {v} (Compound) Methyltestosterone
Cyclosporine (Compound) binds SLCO1A2 (Gene) and SLCO1A2 (Gene) is bound by Methyltestosterone (Compound)
Cyclosporine (Compound) upregulates EDEM1 (Gene) and EDEM1 (Gene) is upregulated by Methyltestosterone (Compound)
Cyclosporine (Compound) downregulates CCDC85B (Gene) and CCDC85B (Gene) is downregulated by Methyltestosterone (Compound)
Cyclosporine (Compound) upregulates DHRS7 (Gene) and DHRS7 (Gene) is downregulated by Methyltestosterone (Compound)
Cyclosporine (Compound) causes Libido decreased (Side Effect) and Libido decreased (Side Effect) is caused by Methyltestosterone (Compound)
Cyclosporine (Compound) binds SLCO1A2 (Gene) and SLCO1A2 (Gene) is bound by Spironolactone (Compound) and Spironolactone (Compound) resembles Methyltestosterone (Compound)
Cyclosporine (Compound) upregulates EDEM1 (Gene) and EDEM1 (Gene) is upregulated by Testosterone Propionate (Compound) and Testosterone Propionate (Compound) resembles Methyltestosterone (Compound)
Cyclosporine (Compound) upregulates FOXO3 (Gene) and FOXO3 (Gene) is upregulated by Danazol (Compound) and Danazol (Compound) resembles Methyltestosterone (Compound)
Cyclosporine (Compound) downregulates CCDC85B (Gene) and CCDC85B (Gene) is downregulated by Testosterone Propionate (Compound) and Testosterone Propionate (Compound) resembles Methyltestosterone (Compound)
Cyclosporine (Compound) upregulates DHRS7 (Gene) and DHRS7 (Gene) is downregulated by Levonorgestrel (Compound) and Levonorgestrel (Compound) resembles Methyltestosterone (Compound)