DDInter825 DDInter248
First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive β cell failure and long-term microvascular and macrovascular complications that lead to co-morbidities and mortalities. Sulfonylureas are one of the insulin secretagogues widely used for the management of type 2 diabetes to lower blood glucose levels. The main effect of SUs is thought to be effective when residual pancreatic β-cells are present, as they work by stimulating the release of insulin from the pancreatic beta cells and they are also thought to exert extra-pancreatic effects, such as increasing the insulin-mediated peripheral glucose uptake. Glimepiride works by stimulating the secretion of insulin granules from
Bumetanide is a sulfamyl diuretic.
Glimepiride {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Bumetanide
Glimepiride {u} (Compound) causes {v} (Side Effect) Hyperhidrosis
Hyperhidrosis {u} (Side Effect) is caused by {v} (Compound) Bumetanide
Glimepiride {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Furosemide
Furosemide {u} (Compound) resembles {v} (Compound) Bumetanide
Glimepiride {u} (Compound) causes {v} (Side Effect) Hyperhidrosis
Hyperhidrosis {u} (Side Effect) is caused by {v} (Compound) Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Bumetanide
Glimepiride {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Metolazone
Metolazone {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Bumetanide
Glimepiride {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Bumetanide
Glimepiride {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) binds {v} (Gene) CA12
CA12 {u} (Gene) is bound by {v} (Compound) Bumetanide
Glimepiride {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) causes {v} (Side Effect) Blood uric acid increased
Blood uric acid increased {u} (Side Effect) is caused by {v} (Compound) Bumetanide
Glimepiride {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Warfarin
Warfarin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Bumetanide
Glimepiride {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Saxagliptin
Saxagliptin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indapamide
Indapamide {u} (Compound) resembles {v} (Compound) Bumetanide
Glimepiride may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) resembles Bumetanide (Compound)
Glimepiride (Compound) causes Hyperhidrosis (Side Effect) and Hyperhidrosis (Side Effect) is caused by Bumetanide (Compound)
Glimepiride may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) resembles Furosemide (Compound) and Furosemide (Compound) resembles Bumetanide (Compound)
Glimepiride (Compound) causes Hyperhidrosis (Side Effect) and Hyperhidrosis (Side Effect) is caused by Indapamide (Compound) and Indapamide (Compound) resembles Bumetanide (Compound)
Glimepiride may cause a moderate interaction that could exacerbate diseases when taken with Metolazone and Metolazone (Compound) resembles Indapamide (Compound) and Indapamide (Compound) resembles Bumetanide (Compound)
Glimepiride may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) treats hypertension (Disease) and hypertension (Disease) is treated by Bumetanide (Compound)
Glimepiride may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) binds CA12 (Gene) and CA12 (Gene) is bound by Bumetanide (Compound)
Glimepiride may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) causes Blood uric acid increased (Side Effect) and Blood uric acid increased (Side Effect) is caused by Bumetanide (Compound)
Glimepiride may cause a moderate interaction that could exacerbate diseases when taken with Warfarin and Warfarin may cause a minor interaction that can limit clinical effects when taken with Indapamide and Indapamide (Compound) resembles Bumetanide (Compound)
Glimepiride may cause a moderate interaction that could exacerbate diseases when taken with Saxagliptin and Saxagliptin may cause a moderate interaction that could exacerbate diseases when taken with Indapamide and Indapamide (Compound) resembles Bumetanide (Compound)