DDInter563 DDInter1654
Dimercaprol is a traditional chelating agent developed by British biochemists at Oxford University during World War II. It was developed as an experimental antidote against the arsenic-based poison gas Lewisite. It has been used clinically since 1949 in arsenic, cadmium and mercury poisoning. In addition, it has in the past been used for the treatment of Wilson's disease, a genetic disorder in which the body tends to retain copper. Dimercaprol has toxic potential, and its use may be followed by a variety of adverse effects.
Selenium is a trace metal in the human body particularly important as a component of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen species [FDA Label]
Dimercaprol {u} (Compound) is included by {v} (Pharmacologic Class) Metal Chelating Activity
Dimercaprol {u} (Compound) causes {v} (Side Effect) Burning sensation
Dimercaprol {u} may lead to a major life threatening interaction when taken with {v} Ferric carboxymaltose
Dimercaprol {u} may lead to a major life threatening interaction when taken with {v} Iron
Dimercaprol (Compound) is included by Metal Chelating Activity (Pharmacologic Class)
Dimercaprol (Compound) causes Burning sensation (Side Effect)
Dimercaprol may lead to a major life threatening interaction when taken with Ferric carboxymaltose
Dimercaprol may lead to a major life threatening interaction when taken with Iron