DDInter416 DDInter1553
This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s. Clotrimazole falls under the _imidazole_ category of _azole_ antifungals, possessing broad-spectrum antimycotic activity. It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers. The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain widespread acceptance for the treatment of mycotic outbreaks such as vaginal yeast infections as well as athlete's foot.
Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as [clozapine] and [olanzapine].
Clotrimazole {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Quetiapine
Clotrimazole {u} (Compound) causes {v} (Side Effect) Cystitis noninfective
Cystitis noninfective {u} (Side Effect) is caused by {v} (Compound) Quetiapine
Clotrimazole {u} (Compound) resembles {v} (Compound) Loperamide
Loperamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Quetiapine
Clotrimazole {u} (Compound) resembles {v} (Compound) Clofedanol
Clofedanol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Quetiapine
Clotrimazole {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Trazodone
Trazodone {u} (Compound) resembles {v} (Compound) Quetiapine
Clotrimazole {u} (Compound) causes {v} (Side Effect) Cystitis noninfective
Cystitis noninfective {u} (Side Effect) is caused by {v} (Compound) Nefazodone
Nefazodone {u} (Compound) resembles {v} (Compound) Quetiapine
Clotrimazole {u} (Compound) resembles {v} (Compound) Loperamide
Loperamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Trazodone
Trazodone {u} (Compound) resembles {v} (Compound) Quetiapine
Clotrimazole {u} (Compound) resembles {v} (Compound) Methadone
Methadone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Trospium
Trospium {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Quetiapine
Clotrimazole {u} (Compound) causes {v} (Side Effect) Cystitis noninfective
Cystitis noninfective {u} (Side Effect) is caused by {v} (Compound) Metronidazole
Metronidazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Quetiapine
Clotrimazole {u} (Compound) causes {v} (Side Effect) Aspartate aminotransferase increased
Aspartate aminotransferase increased {u} (Side Effect) is caused by {v} (Compound) Tamoxifen
Tamoxifen {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Quetiapine
Clotrimazole (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Quetiapine (Compound)
Clotrimazole (Compound) causes Cystitis noninfective (Side Effect) and Cystitis noninfective (Side Effect) is caused by Quetiapine (Compound)
Clotrimazole (Compound) resembles Loperamide (Compound) and Loperamide may cause a moderate interaction that could exacerbate diseases when taken with Quetiapine
Clotrimazole (Compound) resembles Clofedanol (Compound) and Clofedanol may cause a moderate interaction that could exacerbate diseases when taken with Quetiapine
Clotrimazole (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Trazodone (Compound) and Trazodone (Compound) resembles Quetiapine (Compound)
Clotrimazole (Compound) causes Cystitis noninfective (Side Effect) and Cystitis noninfective (Side Effect) is caused by Nefazodone (Compound) and Nefazodone (Compound) resembles Quetiapine (Compound)
Clotrimazole (Compound) resembles Loperamide (Compound) and Loperamide may cause a moderate interaction that could exacerbate diseases when taken with Trazodone and Trazodone (Compound) resembles Quetiapine (Compound)
Clotrimazole (Compound) resembles Methadone (Compound) and Methadone may cause a moderate interaction that could exacerbate diseases when taken with Trospium and Trospium may cause a moderate interaction that could exacerbate diseases when taken with Quetiapine
Clotrimazole (Compound) causes Cystitis noninfective (Side Effect) and Cystitis noninfective (Side Effect) is caused by Metronidazole (Compound) and Metronidazole may cause a minor interaction that can limit clinical effects when taken with Quetiapine
Clotrimazole (Compound) causes Aspartate aminotransferase increased (Side Effect) and Aspartate aminotransferase increased (Side Effect) is caused by Tamoxifen (Compound) and Tamoxifen may cause a moderate interaction that could exacerbate diseases when taken with Quetiapine