DDInter600 DDInter1960
Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.
Ziconotide (also known as SNX-111) is a neurotoxic peptide derived from the cone snail _Conus magus_ comprising 25 amino acids with three disulphide bonds.[A202835, L13389] Other such peptides, collectively termed conotoxins, exist, and some have shown efficacy in binding specific subsets of calcium channels; ziconotide is used in part because it can be synthesized without loss of proper bond formation or structural elements.[A202829, A202832] Ziconotide is used to manage severe chronic pain refractory to other methods, through its ability to inhibit N-type calcium channels involved in nociceptive signalling.[A202829, A202835, A202838, A202841, A202850, A202859, L13389] Ziconotide was granted FDA approval on December 28, 2004 for marketing by TerSera therapeutics LLC. under the name Prialt. To date, ziconotide is the only calcium channel blocking peptide approved for use by the FDA.
Doxylamine {u} (Compound) resembles {v} (Compound) Toremifene
Doxylamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Carbinoxamine
Doxylamine {u} (Compound) resembles {v} (Compound) Chloropyramine
Doxylamine {u} (Compound) binds {v} (Gene) HRH1
Doxylamine {u} (Compound) upregulates {v} (Gene) KIT
Doxylamine {u} (Compound) downregulates {v} (Gene) IGFBP2
Doxylamine {u} (Compound) causes {v} (Side Effect) Decreased appetite
Doxylamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Clozapine
Doxylamine {u} may lead to a major life threatening interaction when taken with {v} Zonisamide
Doxylamine {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Disopyramide
Doxylamine (Compound) resembles Toremifene (Compound)
Doxylamine may cause a moderate interaction that could exacerbate diseases when taken with Carbinoxamine
Doxylamine (Compound) resembles Chloropyramine (Compound)
Doxylamine (Compound) binds HRH1 (Gene)
Doxylamine (Compound) upregulates KIT (Gene)
Doxylamine (Compound) downregulates IGFBP2 (Gene)
Doxylamine (Compound) causes Decreased appetite (Side Effect)
Doxylamine may cause a moderate interaction that could exacerbate diseases when taken with Clozapine
Doxylamine may lead to a major life threatening interaction when taken with Zonisamide
Doxylamine (Compound) resembles Disopyramide (Compound) and Doxylamine may cause a moderate interaction that could exacerbate diseases when taken with Disopyramide