DDInter790 DDInter688
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of water from the body. Furosemide has a fast onset and short duration of action and has been used safely and effectively in both pediatric and adult patients. The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential. In addition to oral formulations, the solution for intravenous and intramuscular administration is also available, which is typically limited to patients who are unable to take oral medication or for patients in emergency clinical situations.
Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on hemodialysis in February, 2017.
Furosemide {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Torasemide
Torasemide {u} may lead to a major life threatening interaction when taken with {v} Etelcalcetide
Furosemide {u} (Compound) binds {v} (Gene) SLC12A1
SLC12A1 {u} (Gene) is bound by {v} (Compound) Torasemide
Torasemide {u} may lead to a major life threatening interaction when taken with {v} Etelcalcetide
Furosemide {u} (Compound) palliates {v} (Disease) chronic kidney failure
chronic kidney failure {u} (Disease) is palliated by {v} (Compound) Torasemide
Torasemide {u} may lead to a major life threatening interaction when taken with {v} Etelcalcetide
Furosemide {u} (Compound) is included by {v} (Pharmacologic Class) Increased Diuresis at Loop of Henle
Increased Diuresis at Loop of Henle {u} (Pharmacologic Class) includes {v} (Compound) Torasemide
Torasemide {u} may lead to a major life threatening interaction when taken with {v} Etelcalcetide
Furosemide {u} (Compound) causes {v} (Side Effect) Rash
Rash {u} (Side Effect) is caused by {v} (Compound) Torasemide
Torasemide {u} may lead to a major life threatening interaction when taken with {v} Etelcalcetide
Furosemide {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amifostine
Amifostine {u} may lead to a major life threatening interaction when taken with {v} Etelcalcetide
Furosemide (Compound) treats hypertension (Disease) and hypertension (Disease) is treated by Torasemide (Compound) and Torasemide may lead to a major life threatening interaction when taken with Etelcalcetide
Furosemide (Compound) binds SLC12A1 (Gene) and SLC12A1 (Gene) is bound by Torasemide (Compound) and Torasemide may lead to a major life threatening interaction when taken with Etelcalcetide
Furosemide (Compound) palliates chronic kidney failure (Disease) and chronic kidney failure (Disease) is palliated by Torasemide (Compound) and Torasemide may lead to a major life threatening interaction when taken with Etelcalcetide
Furosemide (Compound) is included by Increased Diuresis at Loop of Henle (Pharmacologic Class) and Increased Diuresis at Loop of Henle (Pharmacologic Class) includes Torasemide (Compound) and Torasemide may lead to a major life threatening interaction when taken with Etelcalcetide
Furosemide (Compound) causes Rash (Side Effect) and Rash (Side Effect) is caused by Torasemide (Compound) and Torasemide may lead to a major life threatening interaction when taken with Etelcalcetide
Furosemide (Compound) resembles Indapamide (Compound) and Indapamide may cause a moderate interaction that could exacerbate diseases when taken with Amifostine and Amifostine may lead to a major life threatening interaction when taken with Etelcalcetide