DDInter1164 DDInter957
Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173] Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels. Another well-known benefit of this drug is modest weight loss, making it an effective choice for obese patients type II diabetes. Metformin was first approved in Canada in 1972, and received subsequent FDA approval in the US in 1995.
Iodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.
Metformin {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Metformin {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Diatrizoate
Diatrizoate {u} (Compound) resembles {v} (Compound) Iodipamide
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Norethisterone
Norethisterone {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Norethisterone
Norethisterone {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indomethacin
Indomethacin {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Indomethacin
Indomethacin {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Metformin {u} may lead to a major life threatening interaction when taken with {v} Gatifloxacin
Gatifloxacin {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Metformin {u} may lead to a major life threatening interaction when taken with {v} Gatifloxacin
Gatifloxacin {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Metformin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Estradiol
Estradiol {u} (Compound) downregulates {v} (Gene) GRB7
GRB7 {u} (Gene) is downregulated by {v} (Compound) Iodipamide
Metformin {u} (Compound) treats {v} (Disease) type 2 diabetes mellitus
type 2 diabetes mellitus {u} (Disease) is associated with {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Metformin (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Iodipamide (Compound)
Metformin (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Diatrizoate (Compound) and Diatrizoate (Compound) resembles Iodipamide (Compound)
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Norethisterone and Norethisterone (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Norethisterone and Norethisterone (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Iodipamide (Compound)
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Indomethacin and Indomethacin (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Indomethacin and Indomethacin (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Iodipamide (Compound)
Metformin may lead to a major life threatening interaction when taken with Gatifloxacin and Gatifloxacin (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Metformin may lead to a major life threatening interaction when taken with Gatifloxacin and Gatifloxacin (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Iodipamide (Compound)
Metformin may cause a moderate interaction that could exacerbate diseases when taken with Estradiol and Estradiol (Compound) downregulates GRB7 (Gene) and GRB7 (Gene) is downregulated by Iodipamide (Compound)
Metformin (Compound) treats type 2 diabetes mellitus (Disease) and type 2 diabetes mellitus (Disease) is associated with ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)