DDInter416 DDInter119
This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s. Clotrimazole falls under the _imidazole_ category of _azole_ antifungals, possessing broad-spectrum antimycotic activity. It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers. The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain widespread acceptance for the treatment of mycotic outbreaks such as vaginal yeast infections as well as athlete's foot.
Armodafinil is the enantiopure of the wakefulness-promoting agent modafinil (Provigil), and is indicated to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea (OSA), narcolepsy, or shift work disorder (SWD). Research has shown that armodafinil significantly improves driving simulator performance in patients with SWD. Armodafinil consists of the (−)-R-enantiomer of the racemic modafinil. Armodafinil is produced by the pharmaceutical company Cephalon Inc. (a wholly owned subsidiary of Teva Pharmaceutical Industries Ltd.) and was approved by the U.S. Food and Drug Administration (FDA) in June 2007.
Clotrimazole {u} (Compound) resembles {v} (Compound) Methadone
Clotrimazole {u} (Compound) resembles {v} (Compound) Diphenidol
Clotrimazole {u} (Compound) binds {v} (Gene) CYP2C9
Clotrimazole {u} (Compound) upregulates {v} (Gene) PCK2
Clotrimazole {u} (Compound) is included by {v} (Pharmacologic Class) Azoles
Clotrimazole {u} (Compound) causes {v} (Side Effect) Dermatitis bullous
Clotrimazole (Compound) resembles Methadone (Compound)
Clotrimazole (Compound) resembles Diphenidol (Compound)
Clotrimazole (Compound) binds CYP2C9 (Gene)
Clotrimazole (Compound) upregulates PCK2 (Gene)
Clotrimazole (Compound) is included by Azoles (Pharmacologic Class)
Clotrimazole (Compound) causes Dermatitis bullous (Side Effect)