DDInter350 DDInter456
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.
Chlorambucil {u} (Compound) causes {v} (Side Effect) Pancytopenia
Pancytopenia {u} (Side Effect) is caused by {v} (Compound) Cyclophosphamide
Chlorambucil {u} (Compound) resembles {v} (Compound) Melphalan
Melphalan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cyclophosphamide
Chlorambucil {u} (Compound) causes {v} (Side Effect) Pancytopenia
Pancytopenia {u} (Side Effect) is caused by {v} (Compound) Mechlorethamine
Mechlorethamine {u} (Compound) resembles {v} (Compound) Cyclophosphamide
Chlorambucil {u} (Compound) causes {v} (Side Effect) Infertility
Infertility {u} (Side Effect) is caused by {v} (Compound) Ganciclovir
Ganciclovir {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cyclophosphamide
Chlorambucil {u} (Compound) causes {v} (Side Effect) Hepatotoxicity
Hepatotoxicity {u} (Side Effect) is caused by {v} (Compound) Ofloxacin
Ofloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cyclophosphamide
Chlorambucil {u} (Compound) causes {v} (Side Effect) Inappropriate antidiuretic hormone secretion
Inappropriate antidiuretic hormone secretion {u} (Side Effect) is caused by {v} (Compound) Desmopressin
Desmopressin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cyclophosphamide
Chlorambucil {u} (Compound) causes {v} (Side Effect) Hyperuricaemia
Hyperuricaemia {u} (Side Effect) is caused by {v} (Compound) Moxifloxacin
Moxifloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cyclophosphamide
Chlorambucil {u} (Compound) treats {v} (Disease) ovarian cancer
ovarian cancer {u} (Disease) is treated by {v} (Compound) Melphalan
Melphalan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cyclophosphamide
Chlorambucil {u} (Compound) resembles {v} (Compound) Melphalan
Melphalan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mechlorethamine
Mechlorethamine {u} (Compound) resembles {v} (Compound) Cyclophosphamide
Chlorambucil {u} (Compound) treats {v} (Disease) ovarian cancer
ovarian cancer {u} (Disease) is associated with {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Cyclophosphamide
Chlorambucil (Compound) causes Pancytopenia (Side Effect) and Pancytopenia (Side Effect) is caused by Cyclophosphamide (Compound)
Chlorambucil (Compound) resembles Melphalan (Compound) and Melphalan may cause a moderate interaction that could exacerbate diseases when taken with Cyclophosphamide
Chlorambucil (Compound) causes Pancytopenia (Side Effect) and Pancytopenia (Side Effect) is caused by Mechlorethamine (Compound) and Mechlorethamine (Compound) resembles Cyclophosphamide (Compound)
Chlorambucil (Compound) causes Infertility (Side Effect) and Infertility (Side Effect) is caused by Ganciclovir (Compound) and Ganciclovir may cause a moderate interaction that could exacerbate diseases when taken with Cyclophosphamide
Chlorambucil (Compound) causes Hepatotoxicity (Side Effect) and Hepatotoxicity (Side Effect) is caused by Ofloxacin (Compound) and Ofloxacin may cause a minor interaction that can limit clinical effects when taken with Cyclophosphamide
Chlorambucil (Compound) causes Inappropriate antidiuretic hormone secretion (Side Effect) and Inappropriate antidiuretic hormone secretion (Side Effect) is caused by Desmopressin (Compound) and Desmopressin may cause a moderate interaction that could exacerbate diseases when taken with Cyclophosphamide
Chlorambucil (Compound) causes Hyperuricaemia (Side Effect) and Hyperuricaemia (Side Effect) is caused by Moxifloxacin (Compound) and Moxifloxacin may cause a minor interaction that can limit clinical effects when taken with Cyclophosphamide
Chlorambucil (Compound) treats ovarian cancer (Disease) and ovarian cancer (Disease) is treated by Melphalan (Compound) and Melphalan may cause a moderate interaction that could exacerbate diseases when taken with Cyclophosphamide
Chlorambucil (Compound) resembles Melphalan (Compound) and Melphalan may cause a moderate interaction that could exacerbate diseases when taken with Mechlorethamine and Mechlorethamine (Compound) resembles Cyclophosphamide (Compound)
Chlorambucil (Compound) treats ovarian cancer (Disease) and ovarian cancer (Disease) is associated with ABCB1 (Gene) and ABCB1 (Gene) is bound by Cyclophosphamide (Compound)