DDInter15 DDInter832
One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Acetazolamide {u} (Compound) resembles {v} (Compound) Methazolamide
Acetazolamide {u} (Compound) treats {v} (Disease) epilepsy syndrome
Acetazolamide {u} (Compound) binds {v} (Gene) CYP3A4
Acetazolamide {u} (Compound) is included by {v} (Pharmacologic Class) Sulfonamides
Acetazolamide {u} (Compound) causes {v} (Side Effect) Urine output increased
Acetazolamide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Oxytetracycline
Acetazolamide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Doxepin
Acetazolamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Glimepiride
Acetazolamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nitrous acid
Acetazolamide {u} may lead to a major life threatening interaction when taken with {v} Aminolevulinic acid
Acetazolamide (Compound) resembles Methazolamide (Compound)
Acetazolamide (Compound) treats epilepsy syndrome (Disease)
Acetazolamide (Compound) binds CYP3A4 (Gene)
Acetazolamide (Compound) is included by Sulfonamides (Pharmacologic Class)
Acetazolamide (Compound) causes Urine output increased (Side Effect)
Acetazolamide may cause a minor interaction that can limit clinical effects when taken with Oxytetracycline
Acetazolamide may cause a minor interaction that can limit clinical effects when taken with Doxepin
Acetazolamide may cause a moderate interaction that could exacerbate diseases when taken with Glimepiride
Acetazolamide may cause a moderate interaction that could exacerbate diseases when taken with Nitrous acid
Acetazolamide may lead to a major life threatening interaction when taken with Aminolevulinic acid