DDInter1878 DDInter1662
A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat asthma; HAY fever; urticaria; and rhinitis; and also in veterinary applications. Tripelennamine is administered by various routes, including topically.
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before beneficial effects are noticed. Sertraline displays enhanced safety or tolerability than other classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and other undesirable effects.[A1846,A187075,T28]
Tripelennamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Maprotiline
Maprotiline {u} (Compound) resembles {v} (Compound) Sertraline
Tripelennamine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Sertraline
Tripelennamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Maprotiline
Maprotiline {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Sertraline
Tripelennamine {u} (Compound) resembles {v} (Compound) Dimetacrine
Dimetacrine {u} (Compound) resembles {v} (Compound) Maprotiline
Maprotiline {u} (Compound) resembles {v} (Compound) Sertraline
Tripelennamine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Maprotiline
Maprotiline {u} (Compound) resembles {v} (Compound) Sertraline
Tripelennamine {u} (Compound) resembles {v} (Compound) Chloropyramine
Chloropyramine {u} (Compound) upregulates {v} (Gene) UBQLN2
UBQLN2 {u} (Gene) is upregulated by {v} (Compound) Sertraline
Tripelennamine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is associated with {v} (Disease) schizophrenia
schizophrenia {u} (Disease) is palliated by {v} (Compound) Sertraline
Tripelennamine {u} (Compound) resembles {v} (Compound) Chloropyramine
Chloropyramine {u} (Compound) downregulates {v} (Gene) CDC20
CDC20 {u} (Gene) is downregulated by {v} (Compound) Sertraline
Tripelennamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Brompheniramine
Brompheniramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Maprotiline
Maprotiline {u} (Compound) resembles {v} (Compound) Sertraline
Tripelennamine {u} (Compound) resembles {v} (Compound) Rosiglitazone
Rosiglitazone {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Sertraline
Tripelennamine may cause a moderate interaction that could exacerbate diseases when taken with Maprotiline and Maprotiline (Compound) resembles Sertraline (Compound)
Tripelennamine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Sertraline (Compound)
Tripelennamine may cause a moderate interaction that could exacerbate diseases when taken with Maprotiline and Maprotiline (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Sertraline (Compound)
Tripelennamine (Compound) resembles Dimetacrine (Compound) and Dimetacrine (Compound) resembles Maprotiline (Compound) and Maprotiline (Compound) resembles Sertraline (Compound)
Tripelennamine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Maprotiline (Compound) and Maprotiline (Compound) resembles Sertraline (Compound)
Tripelennamine (Compound) resembles Chloropyramine (Compound) and Chloropyramine (Compound) upregulates UBQLN2 (Gene) and UBQLN2 (Gene) is upregulated by Sertraline (Compound)
Tripelennamine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is associated with schizophrenia (Disease) and schizophrenia (Disease) is palliated by Sertraline (Compound)
Tripelennamine (Compound) resembles Chloropyramine (Compound) and Chloropyramine (Compound) downregulates CDC20 (Gene) and CDC20 (Gene) is downregulated by Sertraline (Compound)
Tripelennamine may cause a moderate interaction that could exacerbate diseases when taken with Brompheniramine and Brompheniramine may cause a moderate interaction that could exacerbate diseases when taken with Maprotiline and Maprotiline (Compound) resembles Sertraline (Compound)
Tripelennamine (Compound) resembles Rosiglitazone (Compound) and Rosiglitazone (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Sertraline (Compound)