DDInter1867 DDInter1055
A phenothiazine used as an antipsychotic agent and as an antiemetic.
Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones such as [gatifloxacin] and [moxifloxacin], is a member of the third generation of fluoroquinolones, colloquially referred to as the "respiratory quinolones" due to improved activity against gram-positive bacteria commonly implicated in respiratory infections.[A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and several South American countries soon after.
Triflupromazine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Levofloxacin
Triflupromazine {u} (Compound) resembles {v} (Compound) Pipotiazine
Pipotiazine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Levofloxacin
Triflupromazine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Ciprofloxacin
Ciprofloxacin {u} (Compound) resembles {v} (Compound) Levofloxacin
Triflupromazine {u} (Compound) resembles {v} (Compound) Ethopropazine
Ethopropazine {u} (Compound) upregulates {v} (Gene) GPATCH8
GPATCH8 {u} (Gene) is upregulated by {v} (Compound) Levofloxacin
Triflupromazine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Sparfloxacin
Sparfloxacin {u} (Compound) resembles {v} (Compound) Levofloxacin
Triflupromazine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) regulates {v} (Gene) TOP2A
TOP2A {u} (Gene) is bound by {v} (Compound) Levofloxacin
Triflupromazine {u} (Compound) resembles {v} (Compound) Desipramine
Desipramine {u} (Compound) binds {v} (Gene) SLC22A2
SLC22A2 {u} (Gene) is bound by {v} (Compound) Levofloxacin
Triflupromazine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) regulates {v} (Gene) ERAP2
ERAP2 {u} (Gene) is upregulated by {v} (Compound) Levofloxacin
Triflupromazine {u} (Compound) resembles {v} (Compound) Perphenazine
Perphenazine {u} (Compound) causes {v} (Side Effect) Dysphagia
Dysphagia {u} (Side Effect) is caused by {v} (Compound) Levofloxacin
Triflupromazine {u} (Compound) resembles {v} (Compound) Thioridazine
Thioridazine {u} (Compound) upregulates {v} (Gene) TRIB3
TRIB3 {u} (Gene) is downregulated by {v} (Compound) Levofloxacin
Triflupromazine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Levofloxacin (Compound)
Triflupromazine (Compound) resembles Pipotiazine (Compound) and Pipotiazine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Levofloxacin (Compound)
Triflupromazine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Ciprofloxacin (Compound) and Ciprofloxacin (Compound) resembles Levofloxacin (Compound)
Triflupromazine (Compound) resembles Ethopropazine (Compound) and Ethopropazine (Compound) upregulates GPATCH8 (Gene) and GPATCH8 (Gene) is upregulated by Levofloxacin (Compound)
Triflupromazine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Sparfloxacin (Compound) and Sparfloxacin (Compound) resembles Levofloxacin (Compound)
Triflupromazine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) regulates TOP2A (Gene) and TOP2A (Gene) is bound by Levofloxacin (Compound)
Triflupromazine (Compound) resembles Desipramine (Compound) and Desipramine (Compound) binds SLC22A2 (Gene) and SLC22A2 (Gene) is bound by Levofloxacin (Compound)
Triflupromazine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) regulates ERAP2 (Gene) and ERAP2 (Gene) is upregulated by Levofloxacin (Compound)
Triflupromazine (Compound) resembles Perphenazine (Compound) and Perphenazine (Compound) causes Dysphagia (Side Effect) and Dysphagia (Side Effect) is caused by Levofloxacin (Compound)
Triflupromazine (Compound) resembles Thioridazine (Compound) and Thioridazine (Compound) upregulates TRIB3 (Gene) and TRIB3 (Gene) is downregulated by Levofloxacin (Compound)