DDInter644 DDInter298
A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma. Early clinical studies of carboplatin were performed in 1982. Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.
Enoxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cisplatin
Cisplatin {u} (Compound) treats {v} (Disease) esophageal cancer
esophageal cancer {u} (Disease) is treated by {v} (Compound) Carboplatin
Enoxacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methotrexate
Methotrexate {u} (Compound) treats {v} (Disease) esophageal cancer
esophageal cancer {u} (Disease) is treated by {v} (Compound) Carboplatin
Enoxacin {u} (Compound) upregulates {v} (Gene) XBP1
XBP1 {u} (Gene) is associated with {v} (Disease) esophageal cancer
esophageal cancer {u} (Disease) is treated by {v} (Compound) Carboplatin
Enoxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Epirubicin
Epirubicin {u} (Compound) treats {v} (Disease) ovarian cancer
ovarian cancer {u} (Disease) is treated by {v} (Compound) Carboplatin
Enoxacin {u} (Compound) upregulates {v} (Gene) XBP1
XBP1 {u} (Gene) regulates {v} (Gene) NQO1
NQO1 {u} (Gene) is bound by {v} (Compound) Carboplatin
Enoxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Capecitabine
Capecitabine {u} (Compound) causes {v} (Side Effect) Venous thrombosis
Venous thrombosis {u} (Side Effect) is caused by {v} (Compound) Carboplatin
Enoxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cisplatin
Cisplatin {u} (Compound) binds {v} (Gene) GSTM1
GSTM1 {u} (Gene) is bound by {v} (Compound) Carboplatin
Enoxacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methotrexate
Methotrexate {u} (Compound) binds {v} (Gene) ABCG2
ABCG2 {u} (Gene) is bound by {v} (Compound) Carboplatin
Enoxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Vinorelbine
Vinorelbine {u} (Compound) causes {v} (Side Effect) Phlebitis
Phlebitis {u} (Side Effect) is caused by {v} (Compound) Carboplatin
Enoxacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methotrexate
Methotrexate {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Carboplatin
Enoxacin may cause a minor interaction that can limit clinical effects when taken with Cisplatin and Cisplatin (Compound) treats esophageal cancer (Disease) and esophageal cancer (Disease) is treated by Carboplatin (Compound)
Enoxacin may cause a moderate interaction that could exacerbate diseases when taken with Methotrexate and Methotrexate (Compound) treats esophageal cancer (Disease) and esophageal cancer (Disease) is treated by Carboplatin (Compound)
Enoxacin (Compound) upregulates XBP1 (Gene) and XBP1 (Gene) is associated with esophageal cancer (Disease) and esophageal cancer (Disease) is treated by Carboplatin (Compound)
Enoxacin may cause a minor interaction that can limit clinical effects when taken with Epirubicin and Epirubicin (Compound) treats ovarian cancer (Disease) and ovarian cancer (Disease) is treated by Carboplatin (Compound)
Enoxacin (Compound) upregulates XBP1 (Gene) and XBP1 (Gene) regulates NQO1 (Gene) and NQO1 (Gene) is bound by Carboplatin (Compound)
Enoxacin may cause a minor interaction that can limit clinical effects when taken with Capecitabine and Capecitabine (Compound) causes Venous thrombosis (Side Effect) and Venous thrombosis (Side Effect) is caused by Carboplatin (Compound)
Enoxacin may cause a minor interaction that can limit clinical effects when taken with Cisplatin and Cisplatin (Compound) binds GSTM1 (Gene) and GSTM1 (Gene) is bound by Carboplatin (Compound)
Enoxacin may cause a moderate interaction that could exacerbate diseases when taken with Methotrexate and Methotrexate (Compound) binds ABCG2 (Gene) and ABCG2 (Gene) is bound by Carboplatin (Compound)
Enoxacin may cause a minor interaction that can limit clinical effects when taken with Vinorelbine and Vinorelbine (Compound) causes Phlebitis (Side Effect) and Phlebitis (Side Effect) is caused by Carboplatin (Compound)
Enoxacin may cause a moderate interaction that could exacerbate diseases when taken with Methotrexate and Methotrexate (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Carboplatin (Compound)