DDInter459 DDInter690
Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. It is used primarily to treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation and its off-label use in the treatment of serotonin syndrome.
A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.
Cyproheptadine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Diphenhydramine
Diphenhydramine {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Ethanol
Cyproheptadine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methadone
Methadone {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Ethanol
Cyproheptadine {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amitriptyline
Amitriptyline {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Ethanol
Cyproheptadine {u} (Compound) resembles {v} (Compound) Mianserin
Mianserin {u} (Compound) binds {v} (Gene) CYP2B6
CYP2B6 {u} (Gene) is bound by {v} (Compound) Ethanol
Cyproheptadine {u} may lead to a major life threatening interaction when taken with {v} Zonisamide
Zonisamide {u} (Compound) binds {v} (Gene) CYP2C19
CYP2C19 {u} (Gene) is bound by {v} (Compound) Ethanol
Cyproheptadine {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cyclobenzaprine
Cyclobenzaprine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Ethanol
Cyproheptadine {u} (Compound) palliates {v} (Disease) schizophrenia
schizophrenia {u} (Disease) is associated with {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Ethanol
Cyproheptadine {u} (Compound) downregulates {v} (Gene) NUCB2
NUCB2 {u} (Gene) is regulated by {v} (Gene) CYP1A1
CYP1A1 {u} (Gene) is bound by {v} (Compound) Ethanol
Cyproheptadine {u} (Compound) upregulates {v} (Gene) TIPARP
TIPARP {u} (Gene) is regulated by {v} (Gene) CYP1A1
CYP1A1 {u} (Gene) is bound by {v} (Compound) Ethanol
Cyproheptadine may cause a moderate interaction that could exacerbate diseases when taken with Diphenhydramine and Diphenhydramine (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Ethanol (Compound)
Cyproheptadine may cause a moderate interaction that could exacerbate diseases when taken with Methadone and Methadone (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Ethanol (Compound)
Cyproheptadine (Compound) resembles Amitriptyline (Compound) and Cyproheptadine may cause a moderate interaction that could exacerbate diseases when taken with Amitriptyline and Amitriptyline (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Ethanol (Compound)
Cyproheptadine (Compound) resembles Mianserin (Compound) and Mianserin (Compound) binds CYP2B6 (Gene) and CYP2B6 (Gene) is bound by Ethanol (Compound)
Cyproheptadine may lead to a major life threatening interaction when taken with Zonisamide and Zonisamide (Compound) binds CYP2C19 (Gene) and CYP2C19 (Gene) is bound by Ethanol (Compound)
Cyproheptadine (Compound) resembles Cyclobenzaprine (Compound) and Cyproheptadine may cause a moderate interaction that could exacerbate diseases when taken with Cyclobenzaprine and Cyclobenzaprine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Ethanol (Compound)
Cyproheptadine (Compound) palliates schizophrenia (Disease) and schizophrenia (Disease) is associated with CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Ethanol (Compound)
Cyproheptadine (Compound) downregulates NUCB2 (Gene) and NUCB2 (Gene) is regulated by CYP1A1 (Gene) and CYP1A1 (Gene) is bound by Ethanol (Compound)
Cyproheptadine (Compound) upregulates TIPARP (Gene) and TIPARP (Gene) is regulated by CYP1A1 (Gene) and CYP1A1 (Gene) is bound by Ethanol (Compound)