DDInter1845 DDInter1344
A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders (From AMA Drug Evaluations Annual, 1994, p311). Tranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine with the chiral centers both located on the cylopropane ring. An irreversible monoamine oxidase inhibitor that is used as an antidepressant (INN tranylcypromine).
Opium is the first substance of the diverse group of the opiates. It has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years by the Sumerians. During the years, opium was used as a sedative and hypnotic, but it was determined to be addictive. Opium is extracted from _Papaver somniferum_, which is more known as poppies. This plant is an integrant of the Papaveraceae family, and it is characterized by solitary leaves and capsulated fruits. Therefore, opium is a sticky brown resin obtained by collecting and drying the latex that exudes from the poppy pods. Once extracted, opium contains two main groups of alkaloids; the psychoactive constituents which are in the category of phenanthrenes and alkaloids that have no central nervous system effect in the category of isoquinolines. Morphine is the most prevalent and principal alkaloid in opium, and it is responsible for most of the harmful effects of opium. Opium has gradually been superseded by a variety of synthetic opioids and general anesthetics. Some of the isolated derivatives of opium are morphine, noscapine, strychnine, veratrine, colchicine, codeine, and quinine. Opium is a prohibited drug of abuse in most countries, but the illegal production of this drug and its derivatives keeps being registered. There is some legal production of opium in different countries for the obtention of alkaloids by extraction.
Tranylcypromine {u} (Compound) resembles {v} (Compound) Ethotoin
Ethotoin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Tranylcypromine {u} (Compound) resembles {v} (Compound) Phensuximide
Phensuximide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Tranylcypromine {u} (Compound) resembles {v} (Compound) Phenelzine
Phenelzine {u} may lead to a major life threatening interaction when taken with {v} Opium
Tranylcypromine {u} (Compound) resembles {v} (Compound) Ethotoin
Ethotoin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Carbinoxamine
Carbinoxamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Tranylcypromine {u} (Compound) resembles {v} (Compound) Phensuximide
Phensuximide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Carbinoxamine
Carbinoxamine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Tranylcypromine {u} (Compound) resembles {v} (Compound) Phentermine
Phentermine {u} (Compound) resembles {v} (Compound) Phenacemide
Phenacemide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Tranylcypromine {u} (Compound) resembles {v} (Compound) Ethotoin
Ethotoin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mepyramine
Mepyramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Tranylcypromine {u} (Compound) resembles {v} (Compound) Phensuximide
Phensuximide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mepyramine
Mepyramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Tranylcypromine {u} (Compound) resembles {v} (Compound) Dextroamphetamine
Dextroamphetamine {u} (Compound) resembles {v} (Compound) Phenacemide
Phenacemide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Tranylcypromine {u} (Compound) resembles {v} (Compound) Benzyl alcohol
Benzyl alcohol {u} (Compound) resembles {v} (Compound) Selegiline
Selegiline {u} may lead to a major life threatening interaction when taken with {v} Opium
Tranylcypromine (Compound) resembles Ethotoin (Compound) and Ethotoin may cause a moderate interaction that could exacerbate diseases when taken with Opium
Tranylcypromine (Compound) resembles Phensuximide (Compound) and Phensuximide may cause a moderate interaction that could exacerbate diseases when taken with Opium
Tranylcypromine (Compound) resembles Phenelzine (Compound) and Phenelzine may lead to a major life threatening interaction when taken with Opium
Tranylcypromine (Compound) resembles Ethotoin (Compound) and Ethotoin may cause a moderate interaction that could exacerbate diseases when taken with Carbinoxamine and Carbinoxamine may cause a moderate interaction that could exacerbate diseases when taken with Opium
Tranylcypromine (Compound) resembles Phensuximide (Compound) and Phensuximide may cause a moderate interaction that could exacerbate diseases when taken with Carbinoxamine and Carbinoxamine may cause a moderate interaction that could exacerbate diseases when taken with Opium
Tranylcypromine (Compound) resembles Phentermine (Compound) and Phentermine (Compound) resembles Phenacemide (Compound) and Phenacemide may cause a moderate interaction that could exacerbate diseases when taken with Opium
Tranylcypromine (Compound) resembles Ethotoin (Compound) and Ethotoin may cause a moderate interaction that could exacerbate diseases when taken with Mepyramine and Mepyramine may cause a moderate interaction that could exacerbate diseases when taken with Opium
Tranylcypromine (Compound) resembles Phensuximide (Compound) and Phensuximide may cause a moderate interaction that could exacerbate diseases when taken with Mepyramine and Mepyramine may cause a moderate interaction that could exacerbate diseases when taken with Opium
Tranylcypromine (Compound) resembles Dextroamphetamine (Compound) and Dextroamphetamine (Compound) resembles Phenacemide (Compound) and Phenacemide may cause a moderate interaction that could exacerbate diseases when taken with Opium
Tranylcypromine (Compound) resembles Benzyl alcohol (Compound) and Benzyl alcohol (Compound) resembles Selegiline (Compound) and Selegiline may lead to a major life threatening interaction when taken with Opium