DDInter655 DDInter1662
An anthracycline which is the 4&#39;-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before beneficial effects are noticed. Sertraline displays enhanced safety or tolerability than other classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and other undesirable effects.[A1846,A187075,T28]
Epirubicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Maprotiline
Maprotiline {u} (Compound) resembles {v} (Compound) Sertraline
Epirubicin {u} (Compound) upregulates {v} (Gene) MAOA
MAOA {u} (Gene) is bound by {v} (Compound) Sertraline
Epirubicin {u} (Compound) upregulates {v} (Gene) FOXO4
FOXO4 {u} (Gene) is upregulated by {v} (Compound) Sertraline
Epirubicin {u} (Compound) downregulates {v} (Gene) HMOX1
HMOX1 {u} (Gene) is upregulated by {v} (Compound) Sertraline
Epirubicin {u} (Compound) binds {v} (Gene) DHCR7
DHCR7 {u} (Gene) is upregulated by {v} (Compound) Sertraline
Epirubicin {u} (Compound) downregulates {v} (Gene) JMJD6
JMJD6 {u} (Gene) is downregulated by {v} (Compound) Sertraline
Epirubicin {u} (Compound) causes {v} (Side Effect) Anaphylactic shock
Anaphylactic shock {u} (Side Effect) is caused by {v} (Compound) Sertraline
Epirubicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Maprotiline
Maprotiline {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Sertraline
Epirubicin {u} (Compound) upregulates {v} (Gene) MAOA
MAOA {u} (Gene) is associated with {v} (Disease) schizophrenia
schizophrenia {u} (Disease) is palliated by {v} (Compound) Sertraline
Epirubicin {u} (Compound) upregulates {v} (Gene) FOXO4
FOXO4 {u} (Gene) is regulated by {v} (Gene) ELOVL6
ELOVL6 {u} (Gene) is upregulated by {v} (Compound) Sertraline
Epirubicin may cause a moderate interaction that could exacerbate diseases when taken with Maprotiline and Maprotiline (Compound) resembles Sertraline (Compound)
Epirubicin (Compound) upregulates MAOA (Gene) and MAOA (Gene) is bound by Sertraline (Compound)
Epirubicin (Compound) upregulates FOXO4 (Gene) and FOXO4 (Gene) is upregulated by Sertraline (Compound)
Epirubicin (Compound) downregulates HMOX1 (Gene) and HMOX1 (Gene) is upregulated by Sertraline (Compound)
Epirubicin (Compound) binds DHCR7 (Gene) and DHCR7 (Gene) is upregulated by Sertraline (Compound)
Epirubicin (Compound) downregulates JMJD6 (Gene) and JMJD6 (Gene) is downregulated by Sertraline (Compound)
Epirubicin (Compound) causes Anaphylactic shock (Side Effect) and Anaphylactic shock (Side Effect) is caused by Sertraline (Compound)
Epirubicin may cause a moderate interaction that could exacerbate diseases when taken with Maprotiline and Maprotiline (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Sertraline (Compound)
Epirubicin (Compound) upregulates MAOA (Gene) and MAOA (Gene) is associated with schizophrenia (Disease) and schizophrenia (Disease) is palliated by Sertraline (Compound)
Epirubicin (Compound) upregulates FOXO4 (Gene) and FOXO4 (Gene) is regulated by ELOVL6 (Gene) and ELOVL6 (Gene) is upregulated by Sertraline (Compound)