DDInter1804 DDInter1139
Ticlopidine is an effective inhibitor of platelet aggregation. It is a prodrug that is metabolised to an active form, which blocks the ADP receptor that is involved in GPIIb/IIIa receptor activation leading to platelet aggregation. Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot take aspirin or in whom aspirin has not worked to prevent a thrombotic stroke. The FDA label includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura, and agranulocytosis, so it is necessary to monitor patients' WBC and platelets when they are taking ticlopidine.
A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Ticlopidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ketoprofen
Ketoprofen {u} (Compound) resembles {v} (Compound) Mefenamic acid
Ticlopidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acetylsalicylic acid
Acetylsalicylic acid {u} (Compound) resembles {v} (Compound) Mefenamic acid
Ticlopidine {u} (Compound) binds {v} (Gene) CYP2C8
CYP2C8 {u} (Gene) is bound by {v} (Compound) Mefenamic acid
Ticlopidine {u} (Compound) causes {v} (Side Effect) Peptic ulcer
Peptic ulcer {u} (Side Effect) is caused by {v} (Compound) Mefenamic acid
Ticlopidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ketoprofen
Ketoprofen {u} (Compound) resembles {v} (Compound) Oxybenzone
Oxybenzone {u} (Compound) resembles {v} (Compound) Mefenamic acid
Ticlopidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Flurbiprofen
Flurbiprofen {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ketoprofen
Ketoprofen {u} (Compound) resembles {v} (Compound) Mefenamic acid
Ticlopidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Meclofenamic acid
Meclofenamic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Flurbiprofen
Flurbiprofen {u} (Compound) resembles {v} (Compound) Mefenamic acid
Ticlopidine {u} (Compound) binds {v} (Gene) CYP2C8
CYP2C8 {u} (Gene) is bound by {v} (Compound) Ketoprofen
Ketoprofen {u} (Compound) resembles {v} (Compound) Mefenamic acid
Ticlopidine {u} (Compound) causes {v} (Side Effect) Peptic ulcer
Peptic ulcer {u} (Side Effect) is caused by {v} (Compound) Ketoprofen
Ketoprofen {u} (Compound) resembles {v} (Compound) Mefenamic acid
Ticlopidine {u} (Compound) causes {v} (Side Effect) Pancytopenia
Pancytopenia {u} (Side Effect) is caused by {v} (Compound) Fenoprofen
Fenoprofen {u} (Compound) resembles {v} (Compound) Mefenamic acid
Ticlopidine may cause a moderate interaction that could exacerbate diseases when taken with Ketoprofen and Ketoprofen (Compound) resembles Mefenamic acid (Compound)
Ticlopidine may cause a moderate interaction that could exacerbate diseases when taken with Acetylsalicylic acid and Acetylsalicylic acid (Compound) resembles Mefenamic acid (Compound)
Ticlopidine (Compound) binds CYP2C8 (Gene) and CYP2C8 (Gene) is bound by Mefenamic acid (Compound)
Ticlopidine (Compound) causes Peptic ulcer (Side Effect) and Peptic ulcer (Side Effect) is caused by Mefenamic acid (Compound)
Ticlopidine may cause a moderate interaction that could exacerbate diseases when taken with Ketoprofen and Ketoprofen (Compound) resembles Oxybenzone (Compound) and Oxybenzone (Compound) resembles Mefenamic acid (Compound)
Ticlopidine may cause a moderate interaction that could exacerbate diseases when taken with Flurbiprofen and Flurbiprofen may cause a moderate interaction that could exacerbate diseases when taken with Ketoprofen and Ketoprofen (Compound) resembles Mefenamic acid (Compound)
Ticlopidine may cause a moderate interaction that could exacerbate diseases when taken with Meclofenamic acid and Meclofenamic acid may cause a moderate interaction that could exacerbate diseases when taken with Flurbiprofen and Flurbiprofen (Compound) resembles Mefenamic acid (Compound)
Ticlopidine (Compound) binds CYP2C8 (Gene) and CYP2C8 (Gene) is bound by Ketoprofen (Compound) and Ketoprofen (Compound) resembles Mefenamic acid (Compound)
Ticlopidine (Compound) causes Peptic ulcer (Side Effect) and Peptic ulcer (Side Effect) is caused by Ketoprofen (Compound) and Ketoprofen (Compound) resembles Mefenamic acid (Compound)
Ticlopidine (Compound) causes Pancytopenia (Side Effect) and Pancytopenia (Side Effect) is caused by Fenoprofen (Compound) and Fenoprofen (Compound) resembles Mefenamic acid (Compound)