DDInter1294 DDInter379
Nilutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors). Consequently, Nilutamide blocks the action of androgens of adrenal and testicular origin that stimulate the growth of normal and malignant prostatic tissue. Prostate cancer is mostly androgen-dependent and can be treated with surgical or chemical castration. To date, antiandrogen monotherapy has not consistently been shown to be equivalent to castration.
Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia. It is marketed under the brand name Pletal by Otsuka Pharmaceutical Co.. Cilostazol works by inhibiting both primary and secondary aggregation and reducing calcium-induced contractions.
Nilutamide {u} (Compound) binds {v} (Gene) CYP2C19
CYP2C19 {u} (Gene) is bound by {v} (Compound) Cilostazol
Nilutamide {u} (Compound) causes {v} (Side Effect) Arthritis
Arthritis {u} (Side Effect) is caused by {v} (Compound) Cilostazol
Nilutamide {u} (Compound) resembles {v} (Compound) Enzalutamide
Enzalutamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cilostazol
Nilutamide {u} (Compound) binds {v} (Gene) CYP2C19
CYP2C19 {u} (Gene) is bound by {v} (Compound) Warfarin
Warfarin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cilostazol
Nilutamide {u} (Compound) causes {v} (Side Effect) Arthritis
Arthritis {u} (Side Effect) is caused by {v} (Compound) Tamoxifen
Tamoxifen {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cilostazol
Nilutamide {u} (Compound) causes {v} (Side Effect) Vomiting
Vomiting {u} (Side Effect) is caused by {v} (Compound) Metronidazole
Metronidazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cilostazol
Nilutamide {u} (Compound) causes {v} (Side Effect) Anaemia
Anaemia {u} (Side Effect) is caused by {v} (Compound) Etravirine
Etravirine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cilostazol
Nilutamide {u} (Compound) resembles {v} (Compound) Flutamide
Flutamide {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Cilostazol
Nilutamide {u} (Compound) binds {v} (Gene) CYP2C19
CYP2C19 {u} (Gene) is bound by {v} (Compound) Etravirine
Etravirine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cilostazol
Nilutamide {u} (Compound) resembles {v} (Compound) Nitisinone
Nitisinone {u} (Compound) causes {v} (Side Effect) Melaena
Melaena {u} (Side Effect) is caused by {v} (Compound) Cilostazol
Nilutamide (Compound) binds CYP2C19 (Gene) and CYP2C19 (Gene) is bound by Cilostazol (Compound)
Nilutamide (Compound) causes Arthritis (Side Effect) and Arthritis (Side Effect) is caused by Cilostazol (Compound)
Nilutamide (Compound) resembles Enzalutamide (Compound) and Enzalutamide may cause a moderate interaction that could exacerbate diseases when taken with Cilostazol
Nilutamide (Compound) binds CYP2C19 (Gene) and CYP2C19 (Gene) is bound by Warfarin (Compound) and Warfarin may cause a minor interaction that can limit clinical effects when taken with Cilostazol
Nilutamide (Compound) causes Arthritis (Side Effect) and Arthritis (Side Effect) is caused by Tamoxifen (Compound) and Tamoxifen may cause a moderate interaction that could exacerbate diseases when taken with Cilostazol
Nilutamide (Compound) causes Vomiting (Side Effect) and Vomiting (Side Effect) is caused by Metronidazole (Compound) and Metronidazole may cause a minor interaction that can limit clinical effects when taken with Cilostazol
Nilutamide (Compound) causes Anaemia (Side Effect) and Anaemia (Side Effect) is caused by Etravirine (Compound) and Etravirine may cause a moderate interaction that could exacerbate diseases when taken with Cilostazol
Nilutamide (Compound) resembles Flutamide (Compound) and Flutamide (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Cilostazol (Compound)
Nilutamide (Compound) binds CYP2C19 (Gene) and CYP2C19 (Gene) is bound by Etravirine (Compound) and Etravirine may cause a moderate interaction that could exacerbate diseases when taken with Cilostazol
Nilutamide (Compound) resembles Nitisinone (Compound) and Nitisinone (Compound) causes Melaena (Side Effect) and Melaena (Side Effect) is caused by Cilostazol (Compound)