DDInter119 DDInter121
Armodafinil is the enantiopure of the wakefulness-promoting agent modafinil (Provigil), and is indicated to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea (OSA), narcolepsy, or shift work disorder (SWD). Research has shown that armodafinil significantly improves driving simulator performance in patients with SWD. Armodafinil consists of the (−)-R-enantiomer of the racemic modafinil. Armodafinil is produced by the pharmaceutical company Cephalon Inc. (a wholly owned subsidiary of Teva Pharmaceutical Industries Ltd.) and was approved by the U.S. Food and Drug Administration (FDA) in June 2007.
Artemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of <i>Plasmodium spp.</i> and may be used to treat infections caused by <i>P. falciparum</i> and unidentified <i>Plasmodium</i> species, including infections acquired in chloroquine-resistant areas.
Artemether {u} (Compound) treats {v} (Disease) malaria
Artemether {u} (Compound) binds {v} (Gene) CYP2D6
Artemether {u} (Compound) upregulates {v} (Gene) HDGFRP3
Artemether {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Griseofulvin
Artemether {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fedratinib
Artemether {u} may lead to a major life threatening interaction when taken with {v} Troleandomycin
Artemether {u} may lead to a major life threatening interaction when taken with {v} Saquinavir
Artemether (Compound) treats malaria (Disease)
Artemether (Compound) binds CYP2D6 (Gene)
Artemether (Compound) upregulates HDGFRP3 (Gene)
Artemether may cause a moderate interaction that could exacerbate diseases when taken with Griseofulvin
Artemether may cause a moderate interaction that could exacerbate diseases when taken with Fedratinib
Artemether may lead to a major life threatening interaction when taken with Troleandomycin
Artemether may lead to a major life threatening interaction when taken with Saquinavir