DDInter815 DDInter313
Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea_ in 1963. It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability.[A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment of severe gram-negative infections including those caused by _Pseudomonas aeruginosa_.[A233325,A234359,A234364] There is the added benefit of synergy when gentamicin is co-administered with other antibacterials such as beta-lactams. This synergistic activity is not only important for the treatment of complex infections, but can also contribute to dose optimization and reduced adverse effects.[A234359,A234364] Although gentamicin is well-established and may be used in a variety of clinical applications,
Cefapirin (INN, also spelled cephapirin), commonly marketed under the trade name Cefadyl, is a first-generation cephalosporin antibiotic that is available in injectable formulations. Production for use in humans has been discontinued in the United States. Cefapirin is partly plasma-bound and is effective against gram-negative and gram-positive organisms.
Gentamicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cefazolin
Cefazolin {u} (Compound) resembles {v} (Compound) Cefapirin
Gentamicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cefixime
Cefixime {u} (Compound) resembles {v} (Compound) Cefapirin
Gentamicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cefalotin
Cefalotin {u} (Compound) resembles {v} (Compound) Cefapirin
Gentamicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cefazolin
Cefazolin {u} (Compound) resembles {v} (Compound) Cefotiam
Cefotiam {u} (Compound) resembles {v} (Compound) Cefapirin
Gentamicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cefixime
Cefixime {u} (Compound) resembles {v} (Compound) Cefotiam
Cefotiam {u} (Compound) resembles {v} (Compound) Cefapirin
Gentamicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ceftazidime
Ceftazidime {u} (Compound) resembles {v} (Compound) Cefotiam
Cefotiam {u} (Compound) resembles {v} (Compound) Cefapirin
Gentamicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cefradine
Cefradine {u} (Compound) resembles {v} (Compound) Cefdinir
Cefdinir {u} (Compound) resembles {v} (Compound) Cefapirin
Gentamicin {u} (Compound) binds {v} (Gene) SLC22A6
SLC22A6 {u} (Gene) is bound by {v} (Compound) Cefotiam
Cefotiam {u} (Compound) resembles {v} (Compound) Cefapirin
Gentamicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cefoxitin
Cefoxitin {u} (Compound) resembles {v} (Compound) Cefalotin
Cefalotin {u} (Compound) resembles {v} (Compound) Cefapirin
Gentamicin {u} (Compound) downregulates {v} (Gene) EBNA1BP2
EBNA1BP2 {u} (Gene) is downregulated by {v} (Compound) Cefotiam
Cefotiam {u} (Compound) resembles {v} (Compound) Cefapirin
Gentamicin may cause a moderate interaction that could exacerbate diseases when taken with Cefazolin and Cefazolin (Compound) resembles Cefapirin (Compound)
Gentamicin may cause a moderate interaction that could exacerbate diseases when taken with Cefixime and Cefixime (Compound) resembles Cefapirin (Compound)
Gentamicin may cause a moderate interaction that could exacerbate diseases when taken with Cefalotin and Cefalotin (Compound) resembles Cefapirin (Compound)
Gentamicin may cause a moderate interaction that could exacerbate diseases when taken with Cefazolin and Cefazolin (Compound) resembles Cefotiam (Compound) and Cefotiam (Compound) resembles Cefapirin (Compound)
Gentamicin may cause a moderate interaction that could exacerbate diseases when taken with Cefixime and Cefixime (Compound) resembles Cefotiam (Compound) and Cefotiam (Compound) resembles Cefapirin (Compound)
Gentamicin may cause a moderate interaction that could exacerbate diseases when taken with Ceftazidime and Ceftazidime (Compound) resembles Cefotiam (Compound) and Cefotiam (Compound) resembles Cefapirin (Compound)
Gentamicin may cause a moderate interaction that could exacerbate diseases when taken with Cefradine and Cefradine (Compound) resembles Cefdinir (Compound) and Cefdinir (Compound) resembles Cefapirin (Compound)
Gentamicin (Compound) binds SLC22A6 (Gene) and SLC22A6 (Gene) is bound by Cefotiam (Compound) and Cefotiam (Compound) resembles Cefapirin (Compound)
Gentamicin may cause a moderate interaction that could exacerbate diseases when taken with Cefoxitin and Cefoxitin (Compound) resembles Cefalotin (Compound) and Cefalotin (Compound) resembles Cefapirin (Compound)
Gentamicin (Compound) downregulates EBNA1BP2 (Gene) and EBNA1BP2 (Gene) is downregulated by Cefotiam (Compound) and Cefotiam (Compound) resembles Cefapirin (Compound)