DDInter256 DDInter527
Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates.[A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative anxiety.[A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed benzodiazepines. Its short duration of action gives butabarbital a high abuse potential, comparable to [secobarbital].[A201977,A201980] Butabarbital was granted FDA approval on 5 June 1939.
Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]
Butabarbital {u} (Compound) binds {v} (Gene) CHRFAM7A
CHRFAM7A {u} (Gene) is bound by {v} (Compound) Dextromethorphan
Butabarbital {u} (Compound) causes {v} (Side Effect) Confusional state
Confusional state {u} (Side Effect) is caused by {v} (Compound) Dextromethorphan
Butabarbital {u} (Compound) resembles {v} (Compound) Thiopental
Thiopental {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dextromethorphan
Butabarbital {u} (Compound) resembles {v} (Compound) Butalbital
Butalbital {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dextromethorphan
Butabarbital {u} (Compound) resembles {v} (Compound) Pentobarbital
Pentobarbital {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dextromethorphan
Butabarbital {u} (Compound) binds {v} (Gene) CHRFAM7A
CHRFAM7A {u} (Gene) is bound by {v} (Compound) Thiopental
Thiopental {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dextromethorphan
Butabarbital {u} (Compound) binds {v} (Gene) CHRNA4
CHRNA4 {u} (Gene) interacts with {v} (Gene) CHRNB2
CHRNB2 {u} (Gene) is bound by {v} (Compound) Dextromethorphan
Butabarbital {u} (Compound) causes {v} (Side Effect) Confusional state
Confusional state {u} (Side Effect) is caused by {v} (Compound) Levorphanol
Levorphanol {u} (Compound) resembles {v} (Compound) Dextromethorphan
Butabarbital {u} (Compound) resembles {v} (Compound) Thiopental
Thiopental {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Dextromethorphan
Butabarbital {u} (Compound) resembles {v} (Compound) Pentobarbital
Pentobarbital {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Dextromethorphan
Butabarbital (Compound) binds CHRFAM7A (Gene) and CHRFAM7A (Gene) is bound by Dextromethorphan (Compound)
Butabarbital (Compound) causes Confusional state (Side Effect) and Confusional state (Side Effect) is caused by Dextromethorphan (Compound)
Butabarbital (Compound) resembles Thiopental (Compound) and Thiopental may cause a moderate interaction that could exacerbate diseases when taken with Dextromethorphan
Butabarbital (Compound) resembles Butalbital (Compound) and Butalbital may cause a moderate interaction that could exacerbate diseases when taken with Dextromethorphan
Butabarbital (Compound) resembles Pentobarbital (Compound) and Pentobarbital may cause a moderate interaction that could exacerbate diseases when taken with Dextromethorphan
Butabarbital (Compound) binds CHRFAM7A (Gene) and CHRFAM7A (Gene) is bound by Thiopental (Compound) and Thiopental may cause a moderate interaction that could exacerbate diseases when taken with Dextromethorphan
Butabarbital (Compound) binds CHRNA4 (Gene) and CHRNA4 (Gene) interacts with CHRNB2 (Gene) and CHRNB2 (Gene) is bound by Dextromethorphan (Compound)
Butabarbital (Compound) causes Confusional state (Side Effect) and Confusional state (Side Effect) is caused by Levorphanol (Compound) and Levorphanol (Compound) resembles Dextromethorphan (Compound)
Butabarbital (Compound) resembles Thiopental (Compound) and Thiopental (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Dextromethorphan (Compound)
Butabarbital (Compound) resembles Pentobarbital (Compound) and Pentobarbital (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Dextromethorphan (Compound)