DDInter1417 DDInter278
Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker. Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric drug. Penbutolol also demonstrates high binding affinity to the 5-hydroxytryptamine receptor 1A with antagonistic effects. This binding characteristic of penbutolol is being investigated for its implications in Antidepressant Therapy. Penbutolol is contraindicated in patients with cardiogenic shock, sinus bradycardia, second and third degree atrioventricular conduction block, bronchial asthma, and those with known hypersensitivity.
Calcium lactate is a salt that consists of two lactate anions for each calcium cation (Ca2+). It is prepared commercially by the neutralization of lactic acid with calcium carbonate or calcium hydroxide. Approved by the FDA as a direct food substance affirmed as generally recognized as safe, calcium lactate is used as a firming agent, flavoring agent, leavening agent, stabilizer, and thickener . Calcium lactate is also found in daily dietary supplements as a source of calcium. It is also available in various hydrate forms, where calcium lactate pentahydrate is the most common.
Penbutolol {u} (Compound) resembles {v} (Compound) Timolol
Penbutolol {u} (Compound) resembles {v} (Compound) Bupranolol
Penbutolol {u} (Compound) treats {v} (Disease) hypertension
Penbutolol {u} (Compound) binds {v} (Gene) ORM1
Penbutolol {u} (Compound) causes {v} (Side Effect) Insomnia
Penbutolol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Levothyroxine
Penbutolol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium oxide
Penbutolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Calcium citrate
Penbutolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nateglinide
Penbutolol {u} may lead to a major life threatening interaction when taken with {v} Dolasetron
Penbutolol (Compound) resembles Timolol (Compound)
Penbutolol (Compound) resembles Bupranolol (Compound)
Penbutolol (Compound) treats hypertension (Disease)
Penbutolol (Compound) binds ORM1 (Gene)
Penbutolol (Compound) causes Insomnia (Side Effect)
Penbutolol may cause a minor interaction that can limit clinical effects when taken with Levothyroxine
Penbutolol may cause a minor interaction that can limit clinical effects when taken with Magnesium oxide
Penbutolol may cause a moderate interaction that could exacerbate diseases when taken with Calcium citrate
Penbutolol may cause a moderate interaction that could exacerbate diseases when taken with Nateglinide
Penbutolol may lead to a major life threatening interaction when taken with Dolasetron