DDInter458 DDInter1141
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus _Beauveria nivea_. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
Cyclosporine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Megestrol acetate
Cyclosporine {u} (Compound) causes {v} (Side Effect) Conjunctival hyperaemia
Conjunctival hyperaemia {u} (Side Effect) is caused by {v} (Compound) Difluprednate
Difluprednate {u} (Compound) resembles {v} (Compound) Megestrol acetate
Cyclosporine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Testosterone
Testosterone {u} (Compound) resembles {v} (Compound) Megestrol acetate
Cyclosporine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Hydrocortisone
Hydrocortisone {u} (Compound) resembles {v} (Compound) Megestrol acetate
Cyclosporine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is associated with {v} (Disease) breast cancer
breast cancer {u} (Disease) is palliated by {v} (Compound) Megestrol acetate
Cyclosporine {u} (Compound) causes {v} (Side Effect) Lacrimation increased
Lacrimation increased {u} (Side Effect) is caused by {v} (Compound) Testosterone
Testosterone {u} (Compound) resembles {v} (Compound) Megestrol acetate
Cyclosporine {u} (Compound) upregulates {v} (Gene) DDIT4
DDIT4 {u} (Gene) is upregulated by {v} (Compound) Ethynodiol
Ethynodiol {u} (Compound) resembles {v} (Compound) Megestrol acetate
Cyclosporine {u} (Compound) downregulates {v} (Gene) DNM1L
DNM1L {u} (Gene) is downregulated by {v} (Compound) Ethynodiol
Ethynodiol {u} (Compound) resembles {v} (Compound) Megestrol acetate
Cyclosporine {u} (Compound) upregulates {v} (Gene) FHL2
FHL2 {u} (Gene) is associated with {v} (Disease) breast cancer
breast cancer {u} (Disease) is palliated by {v} (Compound) Megestrol acetate
Cyclosporine {u} (Compound) upregulates {v} (Gene) DDIT4
DDIT4 {u} (Gene) is upregulated by {v} (Compound) Testosterone
Testosterone {u} (Compound) resembles {v} (Compound) Megestrol acetate
Cyclosporine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Megestrol acetate (Compound)
Cyclosporine (Compound) causes Conjunctival hyperaemia (Side Effect) and Conjunctival hyperaemia (Side Effect) is caused by Difluprednate (Compound) and Difluprednate (Compound) resembles Megestrol acetate (Compound)
Cyclosporine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Testosterone (Compound) and Testosterone (Compound) resembles Megestrol acetate (Compound)
Cyclosporine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Hydrocortisone (Compound) and Hydrocortisone (Compound) resembles Megestrol acetate (Compound)
Cyclosporine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is associated with breast cancer (Disease) and breast cancer (Disease) is palliated by Megestrol acetate (Compound)
Cyclosporine (Compound) causes Lacrimation increased (Side Effect) and Lacrimation increased (Side Effect) is caused by Testosterone (Compound) and Testosterone (Compound) resembles Megestrol acetate (Compound)
Cyclosporine (Compound) upregulates DDIT4 (Gene) and DDIT4 (Gene) is upregulated by Ethynodiol (Compound) and Ethynodiol (Compound) resembles Megestrol acetate (Compound)
Cyclosporine (Compound) downregulates DNM1L (Gene) and DNM1L (Gene) is downregulated by Ethynodiol (Compound) and Ethynodiol (Compound) resembles Megestrol acetate (Compound)
Cyclosporine (Compound) upregulates FHL2 (Gene) and FHL2 (Gene) is associated with breast cancer (Disease) and breast cancer (Disease) is palliated by Megestrol acetate (Compound)
Cyclosporine (Compound) upregulates DDIT4 (Gene) and DDIT4 (Gene) is upregulated by Testosterone (Compound) and Testosterone (Compound) resembles Megestrol acetate (Compound)