DDInter1515 DDInter782
A synthetic anti-inflammatory glucocorticoid derived from [cortisone]. It is biologically inert and converted to [prednisolone] in the liver. Prednisone was granted FDA approval on 21 February 1955.
In April 2018, the U.S. Food and Drug Administration (FDA) and the Swiss company Helsinn approved the intravenous formulation of AKYNZEO® (NEPA, a fixed antiemetic combination of fosnetupitant, 235mg, and palonosetron, 0.25mg) as an alternative treatment option for patients experiencing chemotherapy-induced nausea and vomiting . Fosnetupitant is the pro-drug form of netupitant [FDA label]. Generally, 25% to 30% of patients with a diagnosis of cancer receive chemotherapy as a treatment modality and 70% to 80% of these patients undergoing chemotherapy treatment may experience nausea and vomiting as major side effects. Considered one of the most distressing side effects of chemotherapy, nausea and vomiting has an immense impact on the quality of life of patients receiving certain antineoplastic therapies .
Prednisone {u} (Compound) resembles {v} (Compound) Triamcinolone
Prednisone {u} (Compound) resembles {v} (Compound) Testolactone
Prednisone {u} (Compound) treats {v} (Disease) psoriasis
Prednisone {u} (Compound) binds {v} (Gene) CYP3A4
Prednisone {u} (Compound) upregulates {v} (Gene) VAPB
Prednisone {u} (Compound) palliates {v} (Disease) osteoarthritis
Prednisone {u} (Compound) is included by {v} (Pharmacologic Class) Corticosteroid Hormone Receptor Agonists
Prednisone {u} (Compound) downregulates {v} (Gene) ZDHHC6
Prednisone {u} (Compound) causes {v} (Side Effect) Arthralgia
Prednisone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Aluminum hydroxide
Prednisone (Compound) resembles Triamcinolone (Compound)
Prednisone (Compound) resembles Testolactone (Compound)
Prednisone (Compound) treats psoriasis (Disease)
Prednisone (Compound) binds CYP3A4 (Gene)
Prednisone (Compound) upregulates VAPB (Gene)
Prednisone (Compound) palliates osteoarthritis (Disease)
Prednisone (Compound) is included by Corticosteroid Hormone Receptor Agonists (Pharmacologic Class)
Prednisone (Compound) downregulates ZDHHC6 (Gene)
Prednisone (Compound) causes Arthralgia (Side Effect)
Prednisone may cause a minor interaction that can limit clinical effects when taken with Aluminum hydroxide