DDInter1538 DDInter832
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.
A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Propofol {u} (Compound) resembles {v} (Compound) Fospropofol
Propofol {u} (Compound) treats {v} (Disease) epilepsy syndrome
Propofol {u} (Compound) binds {v} (Gene) CYP2B6
Propofol {u} (Compound) is included by {v} (Pharmacologic Class) General Anesthesia
Propofol {u} (Compound) downregulates {v} (Gene) NPDC1
Propofol {u} (Compound) causes {v} (Side Effect) Bronchospasm
Propofol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Dyphylline
Propofol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metronidazole
Propofol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lapatinib
Propofol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Astemizole
Propofol (Compound) resembles Fospropofol (Compound)
Propofol (Compound) treats epilepsy syndrome (Disease)
Propofol (Compound) binds CYP2B6 (Gene)
Propofol (Compound) is included by General Anesthesia (Pharmacologic Class)
Propofol (Compound) downregulates NPDC1 (Gene)
Propofol (Compound) causes Bronchospasm (Side Effect)
Propofol may cause a minor interaction that can limit clinical effects when taken with Dyphylline
Propofol may cause a minor interaction that can limit clinical effects when taken with Metronidazole
Propofol may cause a moderate interaction that could exacerbate diseases when taken with Lapatinib
Propofol may cause a moderate interaction that could exacerbate diseases when taken with Astemizole