DDInter1845 DDInter985
A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders (From AMA Drug Evaluations Annual, 1994, p311). Tranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine with the chiral centers both located on the cylopropane ring. An irreversible monoamine oxidase inhibitor that is used as an antidepressant (INN tranylcypromine).
Isometheptene is a sympathomimetic drug that causes vasoconstriction. It is used for treating migraines and tension headaches.
Tranylcypromine {u} (Compound) upregulates {v} (Gene) CRIP1
CRIP1 {u} (Gene) is upregulated by {v} (Compound) Isometheptene
Tranylcypromine {u} (Compound) resembles {v} (Compound) Phentermine
Phentermine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Isometheptene
Tranylcypromine {u} (Compound) resembles {v} (Compound) Phendimetrazine
Phendimetrazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Isometheptene
Tranylcypromine {u} (Compound) resembles {v} (Compound) Phenelzine
Phenelzine {u} may lead to a major life threatening interaction when taken with {v} Isometheptene
Tranylcypromine {u} (Compound) upregulates {v} (Gene) CRIP1
CRIP1 {u} (Gene) is regulated by {v} (Gene) RUVBL1
RUVBL1 {u} (Gene) is downregulated by {v} (Compound) Isometheptene
Tranylcypromine {u} (Compound) resembles {v} (Compound) Phentermine
Phentermine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Guanadrel
Guanadrel {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Isometheptene
Tranylcypromine {u} (Compound) resembles {v} (Compound) Phendimetrazine
Phendimetrazine {u} (Compound) binds {v} (Gene) ADRA1A
ADRA1A {u} (Gene) is bound by {v} (Compound) Isometheptene
Tranylcypromine {u} (Compound) resembles {v} (Compound) Phenylpropanolamine
Phenylpropanolamine {u} (Compound) binds {v} (Gene) ADRA1A
ADRA1A {u} (Gene) is bound by {v} (Compound) Isometheptene
Tranylcypromine {u} (Compound) upregulates {v} (Gene) SLC35F2
SLC35F2 {u} (Gene) is regulated by {v} (Gene) ATG3
ATG3 {u} (Gene) is upregulated by {v} (Compound) Isometheptene
Tranylcypromine {u} (Compound) resembles {v} (Compound) Phendimetrazine
Phendimetrazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Formoterol
Formoterol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Isometheptene
Tranylcypromine (Compound) upregulates CRIP1 (Gene) and CRIP1 (Gene) is upregulated by Isometheptene (Compound)
Tranylcypromine (Compound) resembles Phentermine (Compound) and Phentermine may cause a moderate interaction that could exacerbate diseases when taken with Isometheptene
Tranylcypromine (Compound) resembles Phendimetrazine (Compound) and Phendimetrazine may cause a moderate interaction that could exacerbate diseases when taken with Isometheptene
Tranylcypromine (Compound) resembles Phenelzine (Compound) and Phenelzine may lead to a major life threatening interaction when taken with Isometheptene
Tranylcypromine (Compound) upregulates CRIP1 (Gene) and CRIP1 (Gene) is regulated by RUVBL1 (Gene) and RUVBL1 (Gene) is downregulated by Isometheptene (Compound)
Tranylcypromine (Compound) resembles Phentermine (Compound) and Phentermine may cause a moderate interaction that could exacerbate diseases when taken with Guanadrel and Guanadrel may cause a moderate interaction that could exacerbate diseases when taken with Isometheptene
Tranylcypromine (Compound) resembles Phendimetrazine (Compound) and Phendimetrazine (Compound) binds ADRA1A (Gene) and ADRA1A (Gene) is bound by Isometheptene (Compound)
Tranylcypromine (Compound) resembles Phenylpropanolamine (Compound) and Phenylpropanolamine (Compound) binds ADRA1A (Gene) and ADRA1A (Gene) is bound by Isometheptene (Compound)
Tranylcypromine (Compound) upregulates SLC35F2 (Gene) and SLC35F2 (Gene) is regulated by ATG3 (Gene) and ATG3 (Gene) is upregulated by Isometheptene (Compound)
Tranylcypromine (Compound) resembles Phendimetrazine (Compound) and Phendimetrazine may cause a moderate interaction that could exacerbate diseases when taken with Formoterol and Formoterol may cause a moderate interaction that could exacerbate diseases when taken with Isometheptene