DDInter1867 DDInter527
A phenothiazine used as an antipsychotic agent and as an antiemetic.
Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]
Triflupromazine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Dextromethorphan
Triflupromazine {u} (Compound) resembles {v} (Compound) Thioridazine
Thioridazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dextromethorphan
Triflupromazine {u} (Compound) resembles {v} (Compound) Chlorpromazine
Chlorpromazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dextromethorphan
Triflupromazine {u} (Compound) resembles {v} (Compound) Methotrimeprazine
Methotrimeprazine {u} may lead to a major life threatening interaction when taken with {v} Dextromethorphan
Triflupromazine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) regulates {v} (Gene) PGRMC1
PGRMC1 {u} (Gene) is bound by {v} (Compound) Dextromethorphan
Triflupromazine {u} (Compound) resembles {v} (Compound) Thioridazine
Thioridazine {u} (Compound) binds {v} (Gene) CYP2C8
CYP2C8 {u} (Gene) is bound by {v} (Compound) Dextromethorphan
Triflupromazine {u} (Compound) resembles {v} (Compound) Propiomazine
Propiomazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cyproheptadine
Cyproheptadine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dextromethorphan
Triflupromazine {u} (Compound) resembles {v} (Compound) Promethazine
Promethazine {u} may lead to a major life threatening interaction when taken with {v} Tramadol
Tramadol {u} (Compound) resembles {v} (Compound) Dextromethorphan
Triflupromazine {u} (Compound) resembles {v} (Compound) Pipotiazine
Pipotiazine {u} (Compound) resembles {v} (Compound) Methotrimeprazine
Methotrimeprazine {u} may lead to a major life threatening interaction when taken with {v} Dextromethorphan
Triflupromazine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Clobazam
Clobazam {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dextromethorphan
Triflupromazine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Dextromethorphan (Compound)
Triflupromazine (Compound) resembles Thioridazine (Compound) and Thioridazine may cause a moderate interaction that could exacerbate diseases when taken with Dextromethorphan
Triflupromazine (Compound) resembles Chlorpromazine (Compound) and Chlorpromazine may cause a moderate interaction that could exacerbate diseases when taken with Dextromethorphan
Triflupromazine (Compound) resembles Methotrimeprazine (Compound) and Methotrimeprazine may lead to a major life threatening interaction when taken with Dextromethorphan
Triflupromazine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) regulates PGRMC1 (Gene) and PGRMC1 (Gene) is bound by Dextromethorphan (Compound)
Triflupromazine (Compound) resembles Thioridazine (Compound) and Thioridazine (Compound) binds CYP2C8 (Gene) and CYP2C8 (Gene) is bound by Dextromethorphan (Compound)
Triflupromazine (Compound) resembles Propiomazine (Compound) and Propiomazine may cause a moderate interaction that could exacerbate diseases when taken with Cyproheptadine and Cyproheptadine may cause a moderate interaction that could exacerbate diseases when taken with Dextromethorphan
Triflupromazine (Compound) resembles Promethazine (Compound) and Promethazine may lead to a major life threatening interaction when taken with Tramadol and Tramadol (Compound) resembles Dextromethorphan (Compound)
Triflupromazine (Compound) resembles Pipotiazine (Compound) and Pipotiazine (Compound) resembles Methotrimeprazine (Compound) and Methotrimeprazine may lead to a major life threatening interaction when taken with Dextromethorphan
Triflupromazine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Clobazam (Compound) and Clobazam may cause a moderate interaction that could exacerbate diseases when taken with Dextromethorphan