DDInter1313 DDInter178
A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Bendamustine is a nitrogen mustard drug indicated for use in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed during or within six months of treatment with rituximab or a rituximab-containing regimen. Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases resulting in cell death. It is active against both active and quiescent cells, although the exact mechanism of action is unknown.
Norfloxacin {u} (Compound) resembles {v} (Compound) Nalidixic acid
Norfloxacin {u} (Compound) resembles {v} (Compound) Gemifloxacin
Norfloxacin {u} (Compound) binds {v} (Gene) CYP1A1
Norfloxacin {u} (Compound) upregulates {v} (Gene) GHR
Norfloxacin {u} (Compound) is included by {v} (Pharmacologic Class) Quinolones
Norfloxacin {u} (Compound) downregulates {v} (Gene) PRR7
Norfloxacin {u} (Compound) causes {v} (Side Effect) Paraesthesia
Norfloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Melphalan
Norfloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ifosfamide
Norfloxacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Degarelix
Norfloxacin (Compound) resembles Nalidixic acid (Compound)
Norfloxacin (Compound) resembles Gemifloxacin (Compound)
Norfloxacin (Compound) binds CYP1A1 (Gene)
Norfloxacin (Compound) upregulates GHR (Gene)
Norfloxacin (Compound) is included by Quinolones (Pharmacologic Class)
Norfloxacin (Compound) downregulates PRR7 (Gene)
Norfloxacin (Compound) causes Paraesthesia (Side Effect)
Norfloxacin may cause a minor interaction that can limit clinical effects when taken with Melphalan
Norfloxacin may cause a minor interaction that can limit clinical effects when taken with Ifosfamide
Norfloxacin may cause a moderate interaction that could exacerbate diseases when taken with Degarelix