DDInter698 DDInter1638
Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid]. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and [risedronic acid]. Etidronic acid was granted FDA approval on 1 September 1977.
Samarium Sm 153 lexidronam is a radioactive medication used to treat pain caused by cancer that has spread to the bone. It is a radiopharmaceutical. Radiopharmaceuticals are radioactive agents that may be used to diagnose some diseases by studying the function of the body's organs or to treat certain diseases.Samarium Sm 153 lexidronam is used to help relieve the bone pain that may occur with certain kinds of cancer. The radioactive samarium is taken up in the bone cancer area and gives off radiation that helps provide relief of pain.
Etidronic acid {u} (Compound) resembles {v} (Compound) Risedronic acid
Risedronic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Bevacizumab
Bevacizumab {u} may lead to a major life threatening interaction when taken with {v} Samarium (153Sm) lexidronam
Etidronic acid {u} (Compound) resembles {v} (Compound) Pamidronic acid
Pamidronic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cisplatin
Cisplatin {u} may lead to a major life threatening interaction when taken with {v} Samarium (153Sm) lexidronam
Etidronic acid {u} (Compound) resembles {v} (Compound) Ibandronate
Ibandronate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iobenguane
Iobenguane {u} may lead to a major life threatening interaction when taken with {v} Samarium (153Sm) lexidronam
Etidronic acid {u} (Compound) upregulates {v} (Gene) PLSCR1
PLSCR1 {u} (Gene) is upregulated by {v} (Compound) Ifosfamide
Ifosfamide {u} may lead to a major life threatening interaction when taken with {v} Samarium (153Sm) lexidronam
Etidronic acid {u} (Compound) upregulates {v} (Gene) ABCC5
ABCC5 {u} (Gene) is bound by {v} (Compound) Mercaptopurine
Mercaptopurine {u} may lead to a major life threatening interaction when taken with {v} Samarium (153Sm) lexidronam
Etidronic acid {u} (Compound) upregulates {v} (Gene) SERPINA3
SERPINA3 {u} (Gene) is upregulated by {v} (Compound) Pazopanib
Pazopanib {u} may lead to a major life threatening interaction when taken with {v} Samarium (153Sm) lexidronam
Etidronic acid {u} (Compound) downregulates {v} (Gene) RAN
RAN {u} (Gene) is downregulated by {v} (Compound) Methotrexate
Methotrexate {u} may lead to a major life threatening interaction when taken with {v} Samarium (153Sm) lexidronam
Etidronic acid {u} (Compound) upregulates {v} (Gene) XBP1
XBP1 {u} (Gene) is downregulated by {v} (Compound) Idarubicin
Idarubicin {u} may lead to a major life threatening interaction when taken with {v} Samarium (153Sm) lexidronam
Etidronic acid {u} (Compound) downregulates {v} (Gene) ACAT2
ACAT2 {u} (Gene) is upregulated by {v} (Compound) Bosutinib
Bosutinib {u} may lead to a major life threatening interaction when taken with {v} Samarium (153Sm) lexidronam
Etidronic acid {u} (Compound) downregulates {v} (Gene) COX8A
COX8A {u} (Gene) is downregulated by {v} (Compound) Ponatinib
Ponatinib {u} may lead to a major life threatening interaction when taken with {v} Samarium (153Sm) lexidronam
Etidronic acid (Compound) resembles Risedronic acid (Compound) and Risedronic acid may cause a moderate interaction that could exacerbate diseases when taken with Bevacizumab and Bevacizumab may lead to a major life threatening interaction when taken with Samarium (153Sm) lexidronam
Etidronic acid (Compound) resembles Pamidronic acid (Compound) and Pamidronic acid may cause a moderate interaction that could exacerbate diseases when taken with Cisplatin and Cisplatin may lead to a major life threatening interaction when taken with Samarium (153Sm) lexidronam
Etidronic acid (Compound) resembles Ibandronate (Compound) and Ibandronate may cause a moderate interaction that could exacerbate diseases when taken with Iobenguane and Iobenguane may lead to a major life threatening interaction when taken with Samarium (153Sm) lexidronam
Etidronic acid (Compound) upregulates PLSCR1 (Gene) and PLSCR1 (Gene) is upregulated by Ifosfamide (Compound) and Ifosfamide may lead to a major life threatening interaction when taken with Samarium (153Sm) lexidronam
Etidronic acid (Compound) upregulates ABCC5 (Gene) and ABCC5 (Gene) is bound by Mercaptopurine (Compound) and Mercaptopurine may lead to a major life threatening interaction when taken with Samarium (153Sm) lexidronam
Etidronic acid (Compound) upregulates SERPINA3 (Gene) and SERPINA3 (Gene) is upregulated by Pazopanib (Compound) and Pazopanib may lead to a major life threatening interaction when taken with Samarium (153Sm) lexidronam
Etidronic acid (Compound) downregulates RAN (Gene) and RAN (Gene) is downregulated by Methotrexate (Compound) and Methotrexate may lead to a major life threatening interaction when taken with Samarium (153Sm) lexidronam
Etidronic acid (Compound) upregulates XBP1 (Gene) and XBP1 (Gene) is downregulated by Idarubicin (Compound) and Idarubicin may lead to a major life threatening interaction when taken with Samarium (153Sm) lexidronam
Etidronic acid (Compound) downregulates ACAT2 (Gene) and ACAT2 (Gene) is upregulated by Bosutinib (Compound) and Bosutinib may lead to a major life threatening interaction when taken with Samarium (153Sm) lexidronam
Etidronic acid (Compound) downregulates COX8A (Gene) and COX8A (Gene) is downregulated by Ponatinib (Compound) and Ponatinib may lead to a major life threatening interaction when taken with Samarium (153Sm) lexidronam