DDInter1066 DDInter1473
Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication. In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local anesthesia for a large variety of surgical procedures [F4349, L5930, L5948]. It ultimately elicits its numbing activity by blocking sodium channels so that the neurons of local tissues that have the medication applied on are transiently incapable of signaling the brain regarding sensations [F4349, L5930, L5948]. In doing so, however, it can block or decrease muscle contractile, resulting in effects like vasodilation, hypotension, and irregular heart rate, among others [F4349, L5930, L5948]. As a result, lidocaine is also considered a class Ib anti-arrhythmic agent [L
Pipecuronium is a piperazinyl androstane derivative which is a non-depolarizing neuromuscular blocking agent.
Lidocaine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Lidocaine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Rocuronium
Rocuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Lidocaine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Rocuronium
Rocuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Lidocaine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Rocuronium
Rocuronium {u} (Compound) resembles {v} (Compound) Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Lidocaine {u} (Compound) causes {v} (Side Effect) Flushing
Flushing {u} (Side Effect) is caused by {v} (Compound) Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Lidocaine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Vecuronium
Vecuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Lidocaine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pancuronium
Pancuronium {u} (Compound) binds {v} (Gene) CHRNB1
CHRNB1 {u} (Gene) is bound by {v} (Compound) Pipecuronium
Lidocaine {u} (Compound) causes {v} (Side Effect) Anaphylactoid reaction
Anaphylactoid reaction {u} (Side Effect) is caused by {v} (Compound) Rocuronium
Rocuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Lidocaine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Dexamethasone
Dexamethasone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Lidocaine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Streptomycin
Streptomycin {u} may lead to a major life threatening interaction when taken with {v} Pancuronium
Pancuronium {u} (Compound) resembles {v} (Compound) Pipecuronium
Lidocaine may cause a moderate interaction that could exacerbate diseases when taken with Pancuronium and Pancuronium (Compound) resembles Pipecuronium (Compound)
Lidocaine may cause a moderate interaction that could exacerbate diseases when taken with Rocuronium and Rocuronium (Compound) resembles Pipecuronium (Compound)
Lidocaine may cause a moderate interaction that could exacerbate diseases when taken with Pancuronium and Pancuronium (Compound) resembles Rocuronium (Compound) and Rocuronium (Compound) resembles Pipecuronium (Compound)
Lidocaine may cause a moderate interaction that could exacerbate diseases when taken with Rocuronium and Rocuronium (Compound) resembles Pancuronium (Compound) and Pancuronium (Compound) resembles Pipecuronium (Compound)
Lidocaine (Compound) causes Flushing (Side Effect) and Flushing (Side Effect) is caused by Pancuronium (Compound) and Pancuronium (Compound) resembles Pipecuronium (Compound)
Lidocaine may cause a moderate interaction that could exacerbate diseases when taken with Pancuronium and Pancuronium (Compound) resembles Vecuronium (Compound) and Vecuronium (Compound) resembles Pipecuronium (Compound)
Lidocaine may cause a moderate interaction that could exacerbate diseases when taken with Pancuronium and Pancuronium (Compound) binds CHRNB1 (Gene) and CHRNB1 (Gene) is bound by Pipecuronium (Compound)
Lidocaine (Compound) causes Anaphylactoid reaction (Side Effect) and Anaphylactoid reaction (Side Effect) is caused by Rocuronium (Compound) and Rocuronium (Compound) resembles Pipecuronium (Compound)
Lidocaine may cause a minor interaction that can limit clinical effects when taken with Dexamethasone and Dexamethasone may cause a moderate interaction that could exacerbate diseases when taken with Pancuronium and Pancuronium (Compound) resembles Pipecuronium (Compound)
Lidocaine may cause a minor interaction that can limit clinical effects when taken with Streptomycin and Streptomycin may lead to a major life threatening interaction when taken with Pancuronium and Pancuronium (Compound) resembles Pipecuronium (Compound)