DDInter1247 DDInter336
Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in the colon. It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval in 1998. Interestingly, selective COX-2 inhibitors (especially celecoxib), have been evaluated as potential cancer chemopreventive and therapeutic drugs in clinical trials for a variety of malignancies.
Moxifloxacin {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Celecoxib
Moxifloxacin {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Etoricoxib
Etoricoxib {u} (Compound) resembles {v} (Compound) Celecoxib
Moxifloxacin {u} may lead to a major life threatening interaction when taken with {v} Vemurafenib
Vemurafenib {u} (Compound) resembles {v} (Compound) Etoricoxib
Etoricoxib {u} (Compound) resembles {v} (Compound) Celecoxib
Moxifloxacin {u} may lead to a major life threatening interaction when taken with {v} Vemurafenib
Vemurafenib {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Celecoxib
Moxifloxacin {u} may lead to a major life threatening interaction when taken with {v} Vemurafenib
Vemurafenib {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Celecoxib
Moxifloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Irinotecan
Irinotecan {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Celecoxib
Moxifloxacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ibuprofen
Ibuprofen {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Celecoxib
Moxifloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Irinotecan
Irinotecan {u} (Compound) upregulates {v} (Gene) PTGS2
PTGS2 {u} (Gene) is bound by {v} (Compound) Celecoxib
Moxifloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Irinotecan
Irinotecan {u} (Compound) treats {v} (Disease) colon cancer
colon cancer {u} (Disease) is palliated by {v} (Compound) Celecoxib
Moxifloxacin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methotrexate
Methotrexate {u} (Compound) upregulates {v} (Gene) PTGS2
PTGS2 {u} (Gene) is bound by {v} (Compound) Celecoxib
Moxifloxacin (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Celecoxib (Compound)
Moxifloxacin (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Etoricoxib (Compound) and Etoricoxib (Compound) resembles Celecoxib (Compound)
Moxifloxacin may lead to a major life threatening interaction when taken with Vemurafenib and Vemurafenib (Compound) resembles Etoricoxib (Compound) and Etoricoxib (Compound) resembles Celecoxib (Compound)
Moxifloxacin may lead to a major life threatening interaction when taken with Vemurafenib and Vemurafenib (Compound) binds ALB (Gene) and ALB (Gene) is bound by Celecoxib (Compound)
Moxifloxacin may lead to a major life threatening interaction when taken with Vemurafenib and Vemurafenib (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Celecoxib (Compound)
Moxifloxacin may cause a minor interaction that can limit clinical effects when taken with Irinotecan and Irinotecan (Compound) binds ALB (Gene) and ALB (Gene) is bound by Celecoxib (Compound)
Moxifloxacin may cause a moderate interaction that could exacerbate diseases when taken with Ibuprofen and Ibuprofen (Compound) binds ALB (Gene) and ALB (Gene) is bound by Celecoxib (Compound)
Moxifloxacin may cause a minor interaction that can limit clinical effects when taken with Irinotecan and Irinotecan (Compound) upregulates PTGS2 (Gene) and PTGS2 (Gene) is bound by Celecoxib (Compound)
Moxifloxacin may cause a minor interaction that can limit clinical effects when taken with Irinotecan and Irinotecan (Compound) treats colon cancer (Disease) and colon cancer (Disease) is palliated by Celecoxib (Compound)
Moxifloxacin may cause a moderate interaction that could exacerbate diseases when taken with Methotrexate and Methotrexate (Compound) upregulates PTGS2 (Gene) and PTGS2 (Gene) is bound by Celecoxib (Compound)