DDInter658 DDInter1763
Eprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). It was developed by Wyeth Pharmaceuticals under the trade name Torisel. Temsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007.
Eprosartan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Eprosartan {u} (Compound) causes {v} (Side Effect) Gastritis
Gastritis {u} (Side Effect) is caused by {v} (Compound) Temsirolimus
Eprosartan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Everolimus
Everolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Eprosartan {u} (Compound) causes {v} (Side Effect) Gastritis
Gastritis {u} (Side Effect) is caused by {v} (Compound) Everolimus
Everolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Eprosartan {u} (Compound) resembles {v} (Compound) Losartan
Losartan {u} (Compound) binds {v} (Gene) CYP3A5
CYP3A5 {u} (Gene) is bound by {v} (Compound) Temsirolimus
Eprosartan {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) downregulates {v} (Gene) TMEM97
TMEM97 {u} (Gene) is downregulated by {v} (Compound) Temsirolimus
Eprosartan {u} (Compound) resembles {v} (Compound) Losartan
Losartan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Eprosartan {u} (Compound) binds {v} (Gene) AGTR1
AGTR1 {u} (Gene) interacts with {v} (Gene) HRAS
HRAS {u} (Gene) is downregulated by {v} (Compound) Temsirolimus
Eprosartan {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is associated with {v} (Gene) MTOR
MTOR {u} (Gene) is bound by {v} (Compound) Temsirolimus
Eprosartan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sirolimus
Sirolimus {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Temsirolimus
Eprosartan may cause a moderate interaction that could exacerbate diseases when taken with Sirolimus and Sirolimus (Compound) resembles Temsirolimus (Compound)
Eprosartan (Compound) causes Gastritis (Side Effect) and Gastritis (Side Effect) is caused by Temsirolimus (Compound)
Eprosartan may cause a moderate interaction that could exacerbate diseases when taken with Sirolimus and Sirolimus (Compound) resembles Everolimus (Compound) and Everolimus (Compound) resembles Temsirolimus (Compound)
Eprosartan (Compound) causes Gastritis (Side Effect) and Gastritis (Side Effect) is caused by Everolimus (Compound) and Everolimus (Compound) resembles Temsirolimus (Compound)
Eprosartan (Compound) resembles Losartan (Compound) and Losartan (Compound) binds CYP3A5 (Gene) and CYP3A5 (Gene) is bound by Temsirolimus (Compound)
Eprosartan (Compound) treats hypertension (Disease) and hypertension (Disease) downregulates TMEM97 (Gene) and TMEM97 (Gene) is downregulated by Temsirolimus (Compound)
Eprosartan (Compound) resembles Losartan (Compound) and Losartan may cause a moderate interaction that could exacerbate diseases when taken with Sirolimus and Sirolimus (Compound) resembles Temsirolimus (Compound)
Eprosartan (Compound) binds AGTR1 (Gene) and AGTR1 (Gene) interacts with HRAS (Gene) and HRAS (Gene) is downregulated by Temsirolimus (Compound)
Eprosartan (Compound) treats hypertension (Disease) and hypertension (Disease) is associated with MTOR (Gene) and MTOR (Gene) is bound by Temsirolimus (Compound)
Eprosartan may cause a moderate interaction that could exacerbate diseases when taken with Sirolimus and Sirolimus (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Temsirolimus (Compound)