DDInter120 DDInter1016
Arsenic trioxide is a chemotherapeutic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents. It is suspected that arsenic trisulfide induces cancer cells to undergo apoptosis. In general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous adverse effects. The enzyme thioredoxin reductase has recently been identified as a target for arsenic trioxide.
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose]. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. [sucrose]). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in patients with cirrhosis.[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.
Arsenic trioxide {u} (Compound) binds {v} (Gene) JUN
Arsenic trioxide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Sulfamethoxazole
Arsenic trioxide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Magnesium citrate
Arsenic trioxide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Formoterol
Arsenic trioxide {u} may lead to a major life threatening interaction when taken with {v} Perphenazine
Arsenic trioxide {u} may lead to a major life threatening interaction when taken with {v} Histrelin
Arsenic trioxide (Compound) binds JUN (Gene)
Arsenic trioxide may cause a minor interaction that can limit clinical effects when taken with Sulfamethoxazole
Arsenic trioxide may cause a moderate interaction that could exacerbate diseases when taken with Magnesium citrate
Arsenic trioxide may cause a moderate interaction that could exacerbate diseases when taken with Formoterol
Arsenic trioxide may lead to a major life threatening interaction when taken with Perphenazine
Arsenic trioxide may lead to a major life threatening interaction when taken with Histrelin