DDInter458 DDInter967
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus _Beauveria nivea_. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
Ioxilan is a tri-iodinated diagnostic contrast agent. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs.
Cyclosporine {u} (Compound) causes {v} (Side Effect) Disorientation
Disorientation {u} (Side Effect) is caused by {v} (Compound) Sotalol
Sotalol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ioxilan
Cyclosporine {u} (Compound) causes {v} (Side Effect) Atrophy
Atrophy {u} (Side Effect) is caused by {v} (Compound) Diclofenac
Diclofenac {u} may lead to a major life threatening interaction when taken with {v} Ioxilan
Cyclosporine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Bisoprolol
Bisoprolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ioxilan
Cyclosporine {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Phenylbutazone
Phenylbutazone {u} may lead to a major life threatening interaction when taken with {v} Ioxilan
Cyclosporine {u} (Compound) downregulates {v} (Gene) CDC20
CDC20 {u} (Gene) is downregulated by {v} (Compound) Triamterene
Triamterene {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ioxilan
Cyclosporine {u} (Compound) downregulates {v} (Gene) PPP2R5E
PPP2R5E {u} (Gene) is downregulated by {v} (Compound) Nabumetone
Nabumetone {u} may lead to a major life threatening interaction when taken with {v} Ioxilan
Cyclosporine {u} (Compound) upregulates {v} (Gene) FUT1
FUT1 {u} (Gene) is downregulated by {v} (Compound) Pindolol
Pindolol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ioxilan
Cyclosporine {u} (Compound) upregulates {v} (Gene) TRIB3
TRIB3 {u} (Gene) is upregulated by {v} (Compound) Pentamidine
Pentamidine {u} may lead to a major life threatening interaction when taken with {v} Ioxilan
Cyclosporine {u} (Compound) upregulates {v} (Gene) ZFP36
ZFP36 {u} (Gene) is upregulated by {v} (Compound) Iopanoic acid
Iopanoic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ioxilan
Cyclosporine {u} (Compound) upregulates {v} (Gene) CTSL
CTSL {u} (Gene) is downregulated by {v} (Compound) Acyclovir
Acyclovir {u} may lead to a major life threatening interaction when taken with {v} Ioxilan
Cyclosporine (Compound) causes Disorientation (Side Effect) and Disorientation (Side Effect) is caused by Sotalol (Compound) and Sotalol may cause a moderate interaction that could exacerbate diseases when taken with Ioxilan
Cyclosporine (Compound) causes Atrophy (Side Effect) and Atrophy (Side Effect) is caused by Diclofenac (Compound) and Diclofenac may lead to a major life threatening interaction when taken with Ioxilan
Cyclosporine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Bisoprolol (Compound) and Bisoprolol may cause a moderate interaction that could exacerbate diseases when taken with Ioxilan
Cyclosporine (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Phenylbutazone (Compound) and Phenylbutazone may lead to a major life threatening interaction when taken with Ioxilan
Cyclosporine (Compound) downregulates CDC20 (Gene) and CDC20 (Gene) is downregulated by Triamterene (Compound) and Triamterene may cause a moderate interaction that could exacerbate diseases when taken with Ioxilan
Cyclosporine (Compound) downregulates PPP2R5E (Gene) and PPP2R5E (Gene) is downregulated by Nabumetone (Compound) and Nabumetone may lead to a major life threatening interaction when taken with Ioxilan
Cyclosporine (Compound) upregulates FUT1 (Gene) and FUT1 (Gene) is downregulated by Pindolol (Compound) and Pindolol may cause a moderate interaction that could exacerbate diseases when taken with Ioxilan
Cyclosporine (Compound) upregulates TRIB3 (Gene) and TRIB3 (Gene) is upregulated by Pentamidine (Compound) and Pentamidine may lead to a major life threatening interaction when taken with Ioxilan
Cyclosporine (Compound) upregulates ZFP36 (Gene) and ZFP36 (Gene) is upregulated by Iopanoic acid (Compound) and Iopanoic acid may cause a moderate interaction that could exacerbate diseases when taken with Ioxilan
Cyclosporine (Compound) upregulates CTSL (Gene) and CTSL (Gene) is downregulated by Acyclovir (Compound) and Acyclovir may lead to a major life threatening interaction when taken with Ioxilan