DDInter1521 DDInter1652
Primidone is an anticonvulsant used to treat essential tremor as well as grand mal, psychomotor, and focal epileptic seizures. Primidone was developed by J Yule Bogue and H C Carrington in 1949. Primidone was granted FDA Approval on 8 March 1954.
Secukinumab is a fully human monoclonal IgG1/κ antibody against interleukin-17A (IL-17A), a proinflammatory cytokine implicated in various chronic immune-mediated inflammatory disorders, such as plaque psoriasis. By blocking the actions of IL-17A, secukinumab works to inhibit the pro-inflammatory pathways that drive immune-mediated inflammatory disorders. Following its first global approval in Japan in December 2014, secukinumab was approved by the European Commission on January 15, 2015, and by the FDA a few days after (January 21, 2015). It is currently approved to treat a number of chronic inflammatory conditions, such as plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, and hidradenitis suppurativa.[L39600,L42280,L48771]
Primidone {u} (Compound) resembles {v} (Compound) Phenobarbital
Primidone {u} (Compound) resembles {v} (Compound) Phenytoin
Primidone {u} (Compound) treats {v} (Disease) epilepsy syndrome
Primidone {u} (Compound) binds {v} (Gene) CYP2C9
Primidone {u} (Compound) is included by {v} (Pharmacologic Class) Decreased Central Nervous System Disorganized Electrical Activity
Primidone {u} (Compound) downregulates {v} (Gene) OXA1L
Primidone {u} (Compound) causes {v} (Side Effect) Psychotic disorder
Primidone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cimetidine
Primidone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Calcifediol
Primidone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Promethazine
Primidone (Compound) resembles Phenobarbital (Compound)
Primidone (Compound) resembles Phenytoin (Compound)
Primidone (Compound) treats epilepsy syndrome (Disease)
Primidone (Compound) binds CYP2C9 (Gene)
Primidone (Compound) is included by Decreased Central Nervous System Disorganized Electrical Activity (Pharmacologic Class)
Primidone (Compound) downregulates OXA1L (Gene)
Primidone (Compound) causes Psychotic disorder (Side Effect)
Primidone may cause a minor interaction that can limit clinical effects when taken with Cimetidine
Primidone may cause a moderate interaction that could exacerbate diseases when taken with Calcifediol
Primidone may cause a moderate interaction that could exacerbate diseases when taken with Promethazine