DDInter1311 DDInter987
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and cardiogenic shock.[A15638,L33160] Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising the heart rate and cardiac output, without vasoconstriction.[A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and a stronger action than [adrenaline]. Isoprenaline was granted FDA approval on 19 February 1948.
Norepinephrine {u} (Compound) resembles {v} (Compound) Isoprenaline
Norepinephrine {u} (Compound) resembles {v} (Compound) Phenylephrine
Phenylephrine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Isoprenaline
Norepinephrine {u} (Compound) resembles {v} (Compound) Isoetharine
Isoetharine {u} (Compound) resembles {v} (Compound) Isoprenaline
Norepinephrine {u} (Compound) resembles {v} (Compound) Arbutamine
Arbutamine {u} (Compound) resembles {v} (Compound) Isoprenaline
Norepinephrine {u} (Compound) resembles {v} (Compound) Epinephrine
Epinephrine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Isoprenaline
Norepinephrine {u} (Compound) resembles {v} (Compound) Levonordefrin
Levonordefrin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Isoprenaline
Norepinephrine {u} (Compound) binds {v} (Gene) ADRB1
ADRB1 {u} (Gene) is bound by {v} (Compound) Isoprenaline
Norepinephrine {u} (Compound) causes {v} (Side Effect) Sweating
Sweating {u} (Side Effect) is caused by {v} (Compound) Isoprenaline
Norepinephrine {u} (Compound) resembles {v} (Compound) Levodopa
Levodopa {u} (Compound) resembles {v} (Compound) and {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Isoprenaline
Norepinephrine {u} (Compound) resembles {v} (Compound) Phenylephrine
Phenylephrine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Formoterol
Formoterol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Isoprenaline
Norepinephrine (Compound) resembles Isoprenaline (Compound)
Norepinephrine (Compound) resembles Phenylephrine (Compound) and Phenylephrine may cause a moderate interaction that could exacerbate diseases when taken with Isoprenaline
Norepinephrine (Compound) resembles Isoetharine (Compound) and Isoetharine (Compound) resembles Isoprenaline (Compound)
Norepinephrine (Compound) resembles Arbutamine (Compound) and Arbutamine (Compound) resembles Isoprenaline (Compound)
Norepinephrine (Compound) resembles Epinephrine (Compound) and Epinephrine may cause a moderate interaction that could exacerbate diseases when taken with Isoprenaline
Norepinephrine (Compound) resembles Levonordefrin (Compound) and Levonordefrin may cause a moderate interaction that could exacerbate diseases when taken with Isoprenaline
Norepinephrine (Compound) binds ADRB1 (Gene) and ADRB1 (Gene) is bound by Isoprenaline (Compound)
Norepinephrine (Compound) causes Sweating (Side Effect) and Sweating (Side Effect) is caused by Isoprenaline (Compound)
Norepinephrine (Compound) resembles Levodopa (Compound) and Levodopa (Compound) resembles Isoprenaline (Compound) and Levodopa may cause a moderate interaction that could exacerbate diseases when taken with Isoprenaline
Norepinephrine (Compound) resembles Phenylephrine (Compound) and Phenylephrine may cause a moderate interaction that could exacerbate diseases when taken with Formoterol and Formoterol may cause a moderate interaction that could exacerbate diseases when taken with Isoprenaline