DDInter1055 DDInter1078
Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones such as [gatifloxacin] and [moxifloxacin], is a member of the third generation of fluoroquinolones, colloquially referred to as the "respiratory quinolones" due to improved activity against gram-positive bacteria commonly implicated in respiratory infections.[A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and several South American countries soon after.
Lisdexamfetamine is a prodrug of [dextroamphetamine], a central nervous system stimulant known as d-amphetamine, covalently attached to the naturally occurring amino acid L-lysine. Lisdexamfetamine is the first chemically formulated prodrug stimulant and was first approved by the FDA in April 2008. It was also approved by Health Canada in February 2009. Lisdexamfetamine works to treat attention deficit hyperactivity disorder and binge eating disorder by blocking dopamine and norepinephrine reuptake and increasing their levels in the extraneuronal space.
Levofloxacin {u} (Compound) causes {v} (Side Effect) Psychotic disorder
Psychotic disorder {u} (Side Effect) is caused by {v} (Compound) Lisdexamfetamine
Levofloxacin {u} (Compound) causes {v} (Side Effect) Psychotic disorder
Psychotic disorder {u} (Side Effect) is caused by {v} (Compound) Lacosamide
Lacosamide {u} (Compound) resembles {v} (Compound) Lisdexamfetamine
Levofloxacin {u} (Compound) causes {v} (Side Effect) Visual impairment
Visual impairment {u} (Side Effect) is caused by {v} (Compound) Labetalol
Labetalol {u} (Compound) resembles {v} (Compound) Lisdexamfetamine
Levofloxacin {u} (Compound) causes {v} (Side Effect) Visual disturbance
Visual disturbance {u} (Side Effect) is caused by {v} (Compound) Thalidomide
Thalidomide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lisdexamfetamine
Levofloxacin {u} (Compound) causes {v} (Side Effect) Eye disorder
Eye disorder {u} (Side Effect) is caused by {v} (Compound) Metronidazole
Metronidazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Lisdexamfetamine
Levofloxacin {u} (Compound) causes {v} (Side Effect) Mania
Mania {u} (Side Effect) is caused by {v} (Compound) Sibutramine
Sibutramine {u} may lead to a major life threatening interaction when taken with {v} Lisdexamfetamine
Levofloxacin {u} (Compound) causes {v} (Side Effect) Myocardial infarction
Myocardial infarction {u} (Side Effect) is caused by {v} (Compound) Vorinostat
Vorinostat {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Lisdexamfetamine
Levofloxacin {u} (Compound) causes {v} (Side Effect) Visual disturbance
Visual disturbance {u} (Side Effect) is caused by {v} (Compound) Hydroxychloroquine
Hydroxychloroquine {u} may lead to a major life threatening interaction when taken with {v} Lisdexamfetamine
Levofloxacin {u} (Compound) causes {v} (Side Effect) Contusion
Contusion {u} (Side Effect) is caused by {v} (Compound) Iobenguane
Iobenguane {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} and {u} may lead to a major life threatening interaction when taken with {v} Lisdexamfetamine
Levofloxacin {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Phenelzine
Phenelzine {u} (Compound) resembles {v} (Compound) Lisdexamfetamine
Levofloxacin (Compound) causes Psychotic disorder (Side Effect) and Psychotic disorder (Side Effect) is caused by Lisdexamfetamine (Compound)
Levofloxacin (Compound) causes Psychotic disorder (Side Effect) and Psychotic disorder (Side Effect) is caused by Lacosamide (Compound) and Lacosamide (Compound) resembles Lisdexamfetamine (Compound)
Levofloxacin (Compound) causes Visual impairment (Side Effect) and Visual impairment (Side Effect) is caused by Labetalol (Compound) and Labetalol (Compound) resembles Lisdexamfetamine (Compound)
Levofloxacin (Compound) causes Visual disturbance (Side Effect) and Visual disturbance (Side Effect) is caused by Thalidomide (Compound) and Thalidomide may cause a moderate interaction that could exacerbate diseases when taken with Lisdexamfetamine
Levofloxacin (Compound) causes Eye disorder (Side Effect) and Eye disorder (Side Effect) is caused by Metronidazole (Compound) and Metronidazole may cause a minor interaction that can limit clinical effects when taken with Lisdexamfetamine
Levofloxacin (Compound) causes Mania (Side Effect) and Mania (Side Effect) is caused by Sibutramine (Compound) and Sibutramine may lead to a major life threatening interaction when taken with Lisdexamfetamine
Levofloxacin (Compound) causes Myocardial infarction (Side Effect) and Myocardial infarction (Side Effect) is caused by Vorinostat (Compound) and Vorinostat may cause a moderate interaction that could exacerbate diseases when taken with Lisdexamfetamine
Levofloxacin (Compound) causes Visual disturbance (Side Effect) and Visual disturbance (Side Effect) is caused by Hydroxychloroquine (Compound) and Hydroxychloroquine may lead to a major life threatening interaction when taken with Lisdexamfetamine
Levofloxacin (Compound) causes Contusion (Side Effect) and Contusion (Side Effect) is caused by Iobenguane (Compound) and Iobenguane may cause a moderate interaction that could exacerbate diseases when taken with Lisdexamfetamine and Iobenguane may lead to a major life threatening interaction when taken with Lisdexamfetamine
Levofloxacin (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Phenelzine (Compound) and Phenelzine (Compound) resembles Lisdexamfetamine (Compound)