DDInter48 DDInter58
Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints. This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals. Allopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and is frequently used in the treatment of chronic gout. It was initially approved by the FDA in 1966 and is now formulated by several manufacturers.
Aluminum hydroxide is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects.
Allopurinol {u} (Compound) causes {v} (Side Effect) Infection
Infection {u} (Side Effect) is caused by {v} (Compound) Aluminum hydroxide
Allopurinol {u} (Compound) causes {v} (Side Effect) Infection
Infection {u} (Side Effect) is caused by {v} (Compound) Fludrocortisone
Fludrocortisone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Aluminum hydroxide
Allopurinol {u} (Compound) binds {v} (Gene) SLC22A8
SLC22A8 {u} (Gene) is bound by {v} (Compound) Digoxin
Digoxin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Aluminum hydroxide
Allopurinol {u} (Compound) causes {v} (Side Effect) Fluid overload
Fluid overload {u} (Side Effect) is caused by {v} (Compound) Liotrix
Liotrix {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Aluminum hydroxide
Allopurinol {u} (Compound) binds {v} (Gene) SLC22A8
SLC22A8 {u} (Gene) is bound by {v} (Compound) Liotrix
Liotrix {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Aluminum hydroxide
Allopurinol {u} (Compound) causes {v} (Side Effect) Fluid overload
Fluid overload {u} (Side Effect) is caused by {v} (Compound) Paricalcitol
Paricalcitol {u} may lead to a major life threatening interaction when taken with {v} Aluminum hydroxide
Allopurinol {u} (Compound) binds {v} (Gene) SLC22A8
SLC22A8 {u} (Gene) is bound by {v} (Compound) Dabrafenib
Dabrafenib {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Aluminum hydroxide
Allopurinol {u} (Compound) causes {v} (Side Effect) Hyponatraemia
Hyponatraemia {u} (Side Effect) is caused by {v} (Compound) Ponatinib
Ponatinib {u} may cause a minor interaction that can limit clinical effects when taken with {v} Aluminum hydroxide
Allopurinol {u} (Compound) causes {v} (Side Effect) Rash maculo-papular
Rash maculo-papular {u} (Side Effect) is caused by {v} (Compound) Dabrafenib
Dabrafenib {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Aluminum hydroxide
Allopurinol {u} (Compound) causes {v} (Side Effect) Rash maculo-papular
Rash maculo-papular {u} (Side Effect) is caused by {v} (Compound) Dolutegravir
Dolutegravir {u} may lead to a major life threatening interaction when taken with {v} Aluminum hydroxide
Allopurinol (Compound) causes Infection (Side Effect) and Infection (Side Effect) is caused by Aluminum hydroxide (Compound)
Allopurinol (Compound) causes Infection (Side Effect) and Infection (Side Effect) is caused by Fludrocortisone (Compound) and Fludrocortisone may cause a minor interaction that can limit clinical effects when taken with Aluminum hydroxide
Allopurinol (Compound) binds SLC22A8 (Gene) and SLC22A8 (Gene) is bound by Digoxin (Compound) and Digoxin may cause a minor interaction that can limit clinical effects when taken with Aluminum hydroxide
Allopurinol (Compound) causes Fluid overload (Side Effect) and Fluid overload (Side Effect) is caused by Liotrix (Compound) and Liotrix may cause a moderate interaction that could exacerbate diseases when taken with Aluminum hydroxide
Allopurinol (Compound) binds SLC22A8 (Gene) and SLC22A8 (Gene) is bound by Liotrix (Compound) and Liotrix may cause a moderate interaction that could exacerbate diseases when taken with Aluminum hydroxide
Allopurinol (Compound) causes Fluid overload (Side Effect) and Fluid overload (Side Effect) is caused by Paricalcitol (Compound) and Paricalcitol may lead to a major life threatening interaction when taken with Aluminum hydroxide
Allopurinol (Compound) binds SLC22A8 (Gene) and SLC22A8 (Gene) is bound by Dabrafenib (Compound) and Dabrafenib may cause a moderate interaction that could exacerbate diseases when taken with Aluminum hydroxide
Allopurinol (Compound) causes Hyponatraemia (Side Effect) and Hyponatraemia (Side Effect) is caused by Ponatinib (Compound) and Ponatinib may cause a minor interaction that can limit clinical effects when taken with Aluminum hydroxide
Allopurinol (Compound) causes Rash maculo-papular (Side Effect) and Rash maculo-papular (Side Effect) is caused by Dabrafenib (Compound) and Dabrafenib may cause a moderate interaction that could exacerbate diseases when taken with Aluminum hydroxide
Allopurinol (Compound) causes Rash maculo-papular (Side Effect) and Rash maculo-papular (Side Effect) is caused by Dolutegravir (Compound) and Dolutegravir may lead to a major life threatening interaction when taken with Aluminum hydroxide