DDInter576 DDInter335
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Disulfiram {u} (Compound) downregulates {v} (Gene) CNDP2
CNDP2 {u} (Gene) is downregulated by {v} (Compound) Cefuroxime
Disulfiram {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Cefuroxime
Disulfiram {u} (Compound) downregulates {v} (Gene) CNDP2
CNDP2 {u} (Gene) regulates {v} (Gene) USP22
USP22 {u} (Gene) is downregulated by {v} (Compound) Cefuroxime
Disulfiram {u} (Compound) downregulates {v} (Gene) DLD
DLD {u} (Gene) is upregulated by {v} (Compound) Cefalotin
Cefalotin {u} (Compound) resembles {v} (Compound) Cefuroxime
Disulfiram {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Ceftibuten
Ceftibuten {u} (Compound) resembles {v} (Compound) Cefuroxime
Disulfiram {u} (Compound) causes {v} (Side Effect) Pain
Pain {u} (Side Effect) is caused by {v} (Compound) Ceftazidime
Ceftazidime {u} (Compound) resembles {v} (Compound) Cefuroxime
Disulfiram {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Cephalexin
Cephalexin {u} (Compound) resembles {v} (Compound) Cefuroxime
Disulfiram {u} (Compound) downregulates {v} (Gene) CNDP2
CNDP2 {u} (Gene) is downregulated by {v} (Compound) Gentamicin
Gentamicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cefuroxime
Disulfiram {u} (Compound) binds {v} (Gene) CYP2E1
CYP2E1 {u} (Gene) is bound by {v} (Compound) Cimetidine
Cimetidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cefuroxime
Disulfiram {u} (Compound) causes {v} (Side Effect) Drowsiness
Drowsiness {u} (Side Effect) is caused by {v} (Compound) Cimetidine
Cimetidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cefuroxime
Disulfiram (Compound) downregulates CNDP2 (Gene) and CNDP2 (Gene) is downregulated by Cefuroxime (Compound)
Disulfiram (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Cefuroxime (Compound)
Disulfiram (Compound) downregulates CNDP2 (Gene) and CNDP2 (Gene) regulates USP22 (Gene) and USP22 (Gene) is downregulated by Cefuroxime (Compound)
Disulfiram (Compound) downregulates DLD (Gene) and DLD (Gene) is upregulated by Cefalotin (Compound) and Cefalotin (Compound) resembles Cefuroxime (Compound)
Disulfiram (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Ceftibuten (Compound) and Ceftibuten (Compound) resembles Cefuroxime (Compound)
Disulfiram (Compound) causes Pain (Side Effect) and Pain (Side Effect) is caused by Ceftazidime (Compound) and Ceftazidime (Compound) resembles Cefuroxime (Compound)
Disulfiram (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Cephalexin (Compound) and Cephalexin (Compound) resembles Cefuroxime (Compound)
Disulfiram (Compound) downregulates CNDP2 (Gene) and CNDP2 (Gene) is downregulated by Gentamicin (Compound) and Gentamicin may cause a moderate interaction that could exacerbate diseases when taken with Cefuroxime
Disulfiram (Compound) binds CYP2E1 (Gene) and CYP2E1 (Gene) is bound by Cimetidine (Compound) and Cimetidine may cause a moderate interaction that could exacerbate diseases when taken with Cefuroxime
Disulfiram (Compound) causes Drowsiness (Side Effect) and Drowsiness (Side Effect) is caused by Cimetidine (Compound) and Cimetidine may cause a moderate interaction that could exacerbate diseases when taken with Cefuroxime