DDInter915 DDInter521
Indacaterol is a novel, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist developed for Novartis for the once-daily management of asthma and chronic obstructive pulmonary disease. It was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011. It is marketed in Europe as Onbrez and in America as Arcapta Neohaler. Indacaterol is provided as its maleate salt form. Indacaterol is also a chiral molecule but only the pure R-enantiomer is dispensed.
Dexmethylphenidate is the dextrorotary form of methylphenidate introduced in 2002. It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant. It is used for treatment of Attention Deficit Hyperactivity Disorder (ADHD)[Label,A177181]. The d-isomer is thought to have greater effect with fewer side effects than the l-isomer or the racemic mixture.
Indacaterol {u} (Compound) causes {v} (Side Effect) Pruritus
Pruritus {u} (Side Effect) is caused by {v} (Compound) Dexmethylphenidate
Indacaterol {u} (Compound) causes {v} (Side Effect) Pruritus
Pruritus {u} (Side Effect) is caused by {v} (Compound) Cyclopentolate
Cyclopentolate {u} (Compound) resembles {v} (Compound) Dexmethylphenidate
Indacaterol {u} (Compound) treats {v} (Disease) asthma
asthma {u} (Disease) is treated by {v} (Compound) Salbutamol
Salbutamol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dexmethylphenidate
Indacaterol {u} (Compound) causes {v} (Side Effect) Upper respiratory tract infection
Upper respiratory tract infection {u} (Side Effect) is caused by {v} (Compound) Ipratropium
Ipratropium {u} (Compound) resembles {v} (Compound) Dexmethylphenidate
Indacaterol {u} (Compound) causes {v} (Side Effect) Chest discomfort
Chest discomfort {u} (Side Effect) is caused by {v} (Compound) Salmeterol
Salmeterol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dexmethylphenidate
Indacaterol {u} (Compound) causes {v} (Side Effect) Malnutrition
Malnutrition {u} (Side Effect) is caused by {v} (Compound) Ioflupane I-123
Ioflupane I-123 {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dexmethylphenidate
Indacaterol {u} (Compound) binds {v} (Gene) ADRB1
ADRB1 {u} (Gene) is bound by {v} (Compound) Formoterol
Formoterol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dexmethylphenidate
Indacaterol {u} (Compound) treats {v} (Disease) asthma
asthma {u} (Disease) is treated by {v} (Compound) Ipratropium
Ipratropium {u} (Compound) resembles {v} (Compound) Dexmethylphenidate
Indacaterol {u} (Compound) causes {v} (Side Effect) Anaemia
Anaemia {u} (Side Effect) is caused by {v} (Compound) Procarbazine
Procarbazine {u} may lead to a major life threatening interaction when taken with {v} Dexmethylphenidate
Indacaterol {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Ipratropium
Ipratropium {u} (Compound) resembles {v} (Compound) Dexmethylphenidate
Indacaterol (Compound) causes Pruritus (Side Effect) and Pruritus (Side Effect) is caused by Dexmethylphenidate (Compound)
Indacaterol (Compound) causes Pruritus (Side Effect) and Pruritus (Side Effect) is caused by Cyclopentolate (Compound) and Cyclopentolate (Compound) resembles Dexmethylphenidate (Compound)
Indacaterol (Compound) treats asthma (Disease) and asthma (Disease) is treated by Salbutamol (Compound) and Salbutamol may cause a moderate interaction that could exacerbate diseases when taken with Dexmethylphenidate
Indacaterol (Compound) causes Upper respiratory tract infection (Side Effect) and Upper respiratory tract infection (Side Effect) is caused by Ipratropium (Compound) and Ipratropium (Compound) resembles Dexmethylphenidate (Compound)
Indacaterol (Compound) causes Chest discomfort (Side Effect) and Chest discomfort (Side Effect) is caused by Salmeterol (Compound) and Salmeterol may cause a moderate interaction that could exacerbate diseases when taken with Dexmethylphenidate
Indacaterol (Compound) causes Malnutrition (Side Effect) and Malnutrition (Side Effect) is caused by Ioflupane I-123 (Compound) and Ioflupane I-123 may cause a moderate interaction that could exacerbate diseases when taken with Dexmethylphenidate
Indacaterol (Compound) binds ADRB1 (Gene) and ADRB1 (Gene) is bound by Formoterol (Compound) and Formoterol may cause a moderate interaction that could exacerbate diseases when taken with Dexmethylphenidate
Indacaterol (Compound) treats asthma (Disease) and asthma (Disease) is treated by Ipratropium (Compound) and Ipratropium (Compound) resembles Dexmethylphenidate (Compound)
Indacaterol (Compound) causes Anaemia (Side Effect) and Anaemia (Side Effect) is caused by Procarbazine (Compound) and Procarbazine may lead to a major life threatening interaction when taken with Dexmethylphenidate
Indacaterol (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Ipratropium (Compound) and Ipratropium (Compound) resembles Dexmethylphenidate (Compound)