DDInter1378 DDInter119
Paclitaxel can cause developmental toxicity, female reproductive toxicity and male reproductive toxicity according to state or federal government labeling requirements.
Armodafinil is the enantiopure of the wakefulness-promoting agent modafinil (Provigil), and is indicated to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea (OSA), narcolepsy, or shift work disorder (SWD). Research has shown that armodafinil significantly improves driving simulator performance in patients with SWD. Armodafinil consists of the (−)-R-enantiomer of the racemic modafinil. Armodafinil is produced by the pharmaceutical company Cephalon Inc. (a wholly owned subsidiary of Teva Pharmaceutical Industries Ltd.) and was approved by the U.S. Food and Drug Administration (FDA) in June 2007.
Paclitaxel {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cabazitaxel
Paclitaxel {u} (Compound) resembles {v} (Compound) Docetaxel
Paclitaxel {u} (Compound) treats {v} (Disease) breast cancer
Paclitaxel {u} (Compound) binds {v} (Gene) CYP3A5
Paclitaxel {u} (Compound) upregulates {v} (Gene) CDCA8
Paclitaxel {u} (Compound) is included by {v} (Pharmacologic Class) Microtubule Inhibition
Paclitaxel {u} (Compound) downregulates {v} (Gene) SCAND1
Paclitaxel {u} (Compound) causes {v} (Side Effect) Swelling face
Paclitaxel {u} may cause a minor interaction that can limit clinical effects when taken with {v} Sparfloxacin
Paclitaxel {u} may cause a minor interaction that can limit clinical effects when taken with {v} Delafloxacin
Paclitaxel may cause a moderate interaction that could exacerbate diseases when taken with Cabazitaxel
Paclitaxel (Compound) resembles Docetaxel (Compound)
Paclitaxel (Compound) treats breast cancer (Disease)
Paclitaxel (Compound) binds CYP3A5 (Gene)
Paclitaxel (Compound) upregulates CDCA8 (Gene)
Paclitaxel (Compound) is included by Microtubule Inhibition (Pharmacologic Class)
Paclitaxel (Compound) downregulates SCAND1 (Gene)
Paclitaxel (Compound) causes Swelling face (Side Effect)
Paclitaxel may cause a minor interaction that can limit clinical effects when taken with Sparfloxacin
Paclitaxel may cause a minor interaction that can limit clinical effects when taken with Delafloxacin