DDInter1515 DDInter1676
A synthetic anti-inflammatory glucocorticoid derived from [cortisone]. It is biologically inert and converted to [prednisolone] in the liver. Prednisone was granted FDA approval on 21 February 1955.
Siponimod, also known as _Mayzent_, by Novartis, is a new drug formulated for the management of Multiple Sclerosis (MS). It was approved by the FDA on March 26, 2019 and by Health Canada on February 20, 2020. This drug is considered a _sphingosine-1-phosphate (S1P) receptor modulator_ and is thought to play a role in suppressing the central nervous system inflammation that is associated with MS [FDA label]. Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system that is chronic and inflammatory, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of life. Symptoms may include but are not limited to fatigue, gait changes, bowel or bladder dysfunction, abnormal muscle twitching, vision disturbance, and depressing or mood swings. MS is one of the most common causes of neurological disability in young adults and is found to occur more frequently in women than in men.[A176474,L5792]
Prednisone {u} (Compound) resembles {v} (Compound) Triamcinolone
Prednisone {u} (Compound) resembles {v} (Compound) Testolactone
Prednisone {u} (Compound) treats {v} (Disease) psoriasis
Prednisone {u} (Compound) binds {v} (Gene) CYP3A4
Prednisone {u} (Compound) upregulates {v} (Gene) VAPB
Prednisone {u} (Compound) palliates {v} (Disease) osteoarthritis
Prednisone {u} (Compound) is included by {v} (Pharmacologic Class) Corticosteroid Hormone Receptor Agonists
Prednisone {u} (Compound) downregulates {v} (Gene) ZDHHC6
Prednisone {u} (Compound) causes {v} (Side Effect) Arthralgia
Prednisone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Aluminum hydroxide
Prednisone (Compound) resembles Triamcinolone (Compound)
Prednisone (Compound) resembles Testolactone (Compound)
Prednisone (Compound) treats psoriasis (Disease)
Prednisone (Compound) binds CYP3A4 (Gene)
Prednisone (Compound) upregulates VAPB (Gene)
Prednisone (Compound) palliates osteoarthritis (Disease)
Prednisone (Compound) is included by Corticosteroid Hormone Receptor Agonists (Pharmacologic Class)
Prednisone (Compound) downregulates ZDHHC6 (Gene)
Prednisone (Compound) causes Arthralgia (Side Effect)
Prednisone may cause a minor interaction that can limit clinical effects when taken with Aluminum hydroxide