DDInter1139 DDInter856
A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated heparin is more specific than LMWH for thrombin. Furthermore, the effects of UH can typically be reversed by using protamine sulfate.
Mefenamic acid {u} (Compound) resembles {v} (Compound) Ketoprofen
Mefenamic acid {u} (Compound) resembles {v} (Compound) Oxybenzone
Mefenamic acid {u} (Compound) binds {v} (Gene) CYP2C8
Mefenamic acid {u} (Compound) upregulates {v} (Gene) SUV39H1
Mefenamic acid {u} (Compound) is included by {v} (Pharmacologic Class) Nonsteroidal Anti-inflammatory Compounds
Mefenamic acid {u} (Compound) downregulates {v} (Gene) DNAJA3
Mefenamic acid {u} (Compound) causes {v} (Side Effect) Somnolence
Mefenamic acid (Compound) resembles Ketoprofen (Compound)
Mefenamic acid (Compound) resembles Oxybenzone (Compound)
Mefenamic acid (Compound) binds CYP2C8 (Gene)
Mefenamic acid (Compound) upregulates SUV39H1 (Gene)
Mefenamic acid (Compound) is included by Nonsteroidal Anti-inflammatory Compounds (Pharmacologic Class)
Mefenamic acid (Compound) downregulates DNAJA3 (Gene)
Mefenamic acid (Compound) causes Somnolence (Side Effect)