DDInter1251 DDInter1396
Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). This drug is an immunosuppressant combined with drugs such as [Cyclosporine] and corticosteroids to prevent organ rejection after hepatic, renal, and cardiac transplants. It is marketed by Roche Pharmaceuticals and was granted FDA approval for the prophylaxis of transplant rejection in 1995. In addition to the above uses, mycophenolate mofetil has also been studied for the treatment of nephritis and other complications of autoimmune diseases. Unlike another immunosuppressant class, the calcineurin inhibitors, MMF generally does not cause nephrotoxicity or fibrosis.[A180799,A180805] Previously, mycophenolic acid
An oligosaccharide antibiotic produced by various streptomyces. [PubChem]
Mycophenolate mofetil {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Kanamycin
Kanamycin {u} (Compound) resembles {v} (Compound) Paromomycin
Mycophenolate mofetil {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Neomycin
Neomycin {u} (Compound) resembles {v} (Compound) Paromomycin
Mycophenolate mofetil {u} (Compound) downregulates {v} (Gene) CDC20
CDC20 {u} (Gene) is downregulated by {v} (Compound) Paromomycin
Mycophenolate mofetil {u} (Compound) causes {v} (Side Effect) Diarrhoea
Diarrhoea {u} (Side Effect) is caused by {v} (Compound) Paromomycin
Mycophenolate mofetil {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Kanamycin
Kanamycin {u} (Compound) resembles {v} (Compound) Tobramycin
Tobramycin {u} (Compound) resembles {v} (Compound) Paromomycin
Mycophenolate mofetil {u} (Compound) downregulates {v} (Gene) CDC20
CDC20 {u} (Gene) is regulated by {v} (Gene) UBQLN2
UBQLN2 {u} (Gene) is upregulated by {v} (Compound) Paromomycin
Mycophenolate mofetil {u} (Compound) causes {v} (Side Effect) Diarrhoea
Diarrhoea {u} (Side Effect) is caused by {v} (Compound) Tobramycin
Tobramycin {u} (Compound) resembles {v} (Compound) Paromomycin
Mycophenolate mofetil {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Kanamycin
Kanamycin {u} (Compound) resembles {v} (Compound) Amikacin
Amikacin {u} (Compound) resembles {v} (Compound) Paromomycin
Mycophenolate mofetil {u} (Compound) downregulates {v} (Gene) CDC20
CDC20 {u} (Gene) is regulated by {v} (Gene) NPDC1
NPDC1 {u} (Gene) is downregulated by {v} (Compound) Paromomycin
Mycophenolate mofetil {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Amikacin
Amikacin {u} (Compound) resembles {v} (Compound) Paromomycin
Mycophenolate mofetil may cause a moderate interaction that could exacerbate diseases when taken with Kanamycin and Kanamycin (Compound) resembles Paromomycin (Compound)
Mycophenolate mofetil may cause a moderate interaction that could exacerbate diseases when taken with Neomycin and Neomycin (Compound) resembles Paromomycin (Compound)
Mycophenolate mofetil (Compound) downregulates CDC20 (Gene) and CDC20 (Gene) is downregulated by Paromomycin (Compound)
Mycophenolate mofetil (Compound) causes Diarrhoea (Side Effect) and Diarrhoea (Side Effect) is caused by Paromomycin (Compound)
Mycophenolate mofetil may cause a moderate interaction that could exacerbate diseases when taken with Kanamycin and Kanamycin (Compound) resembles Tobramycin (Compound) and Tobramycin (Compound) resembles Paromomycin (Compound)
Mycophenolate mofetil (Compound) downregulates CDC20 (Gene) and CDC20 (Gene) is regulated by UBQLN2 (Gene) and UBQLN2 (Gene) is upregulated by Paromomycin (Compound)
Mycophenolate mofetil (Compound) causes Diarrhoea (Side Effect) and Diarrhoea (Side Effect) is caused by Tobramycin (Compound) and Tobramycin (Compound) resembles Paromomycin (Compound)
Mycophenolate mofetil may cause a moderate interaction that could exacerbate diseases when taken with Kanamycin and Kanamycin (Compound) resembles Amikacin (Compound) and Amikacin (Compound) resembles Paromomycin (Compound)
Mycophenolate mofetil (Compound) downregulates CDC20 (Gene) and CDC20 (Gene) is regulated by NPDC1 (Gene) and NPDC1 (Gene) is downregulated by Paromomycin (Compound)
Mycophenolate mofetil (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Amikacin (Compound) and Amikacin (Compound) resembles Paromomycin (Compound)