DDInter350 DDInter1887
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Trovafloxacin is a broad spectrum antibiotic that has been commonly marketed under the brand name Trovan by Pfizer. It exerts its antibacterial activity by inhibiting the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV. It was shown to be more effective against Gram-positive bacteria than Gram-negative bacteria when compared to previous fluoroquinolones. Due to its hepatotoxic potential, trovafloxacin was withdrawn from the market.
Chlorambucil {u} (Compound) causes {v} (Side Effect) Fatigue
Fatigue {u} (Side Effect) is caused by {v} (Compound) Trovafloxacin
Chlorambucil {u} (Compound) resembles {v} (Compound) Melphalan
Melphalan {u} may cause a minor interaction that can limit clinical effects when taken with {v} Trovafloxacin
Chlorambucil {u} (Compound) causes {v} (Side Effect) Fatigue
Fatigue {u} (Side Effect) is caused by {v} (Compound) Gemifloxacin
Gemifloxacin {u} (Compound) resembles {v} (Compound) Trovafloxacin
Chlorambucil {u} (Compound) causes {v} (Side Effect) Dyskinesia
Dyskinesia {u} (Side Effect) is caused by {v} (Compound) Ifosfamide
Ifosfamide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Trovafloxacin
Chlorambucil {u} (Compound) treats {v} (Disease) ovarian cancer
ovarian cancer {u} (Disease) is treated by {v} (Compound) Epirubicin
Epirubicin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Trovafloxacin
Chlorambucil {u} (Compound) resembles {v} (Compound) Melphalan
Melphalan {u} may cause a minor interaction that can limit clinical effects when taken with {v} Gemifloxacin
Gemifloxacin {u} (Compound) resembles {v} (Compound) Trovafloxacin
Chlorambucil {u} (Compound) causes {v} (Side Effect) Dyskinesia
Dyskinesia {u} (Side Effect) is caused by {v} (Compound) Epirubicin
Epirubicin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Trovafloxacin
Chlorambucil {u} (Compound) resembles {v} (Compound) Melphalan
Melphalan {u} may cause a minor interaction that can limit clinical effects when taken with {v} Enoxacin
Enoxacin {u} (Compound) resembles {v} (Compound) Trovafloxacin
Chlorambucil {u} (Compound) treats {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Paclitaxel
Paclitaxel {u} may cause a minor interaction that can limit clinical effects when taken with {v} Trovafloxacin
Chlorambucil {u} (Compound) treats {v} (Disease) hematologic cancer
hematologic cancer {u} (Disease) is associated with {v} (Gene) TOP2A
TOP2A {u} (Gene) is bound by {v} (Compound) Trovafloxacin
Chlorambucil (Compound) causes Fatigue (Side Effect) and Fatigue (Side Effect) is caused by Trovafloxacin (Compound)
Chlorambucil (Compound) resembles Melphalan (Compound) and Melphalan may cause a minor interaction that can limit clinical effects when taken with Trovafloxacin
Chlorambucil (Compound) causes Fatigue (Side Effect) and Fatigue (Side Effect) is caused by Gemifloxacin (Compound) and Gemifloxacin (Compound) resembles Trovafloxacin (Compound)
Chlorambucil (Compound) causes Dyskinesia (Side Effect) and Dyskinesia (Side Effect) is caused by Ifosfamide (Compound) and Ifosfamide may cause a minor interaction that can limit clinical effects when taken with Trovafloxacin
Chlorambucil (Compound) treats ovarian cancer (Disease) and ovarian cancer (Disease) is treated by Epirubicin (Compound) and Epirubicin may cause a minor interaction that can limit clinical effects when taken with Trovafloxacin
Chlorambucil (Compound) resembles Melphalan (Compound) and Melphalan may cause a minor interaction that can limit clinical effects when taken with Gemifloxacin and Gemifloxacin (Compound) resembles Trovafloxacin (Compound)
Chlorambucil (Compound) causes Dyskinesia (Side Effect) and Dyskinesia (Side Effect) is caused by Epirubicin (Compound) and Epirubicin may cause a minor interaction that can limit clinical effects when taken with Trovafloxacin
Chlorambucil (Compound) resembles Melphalan (Compound) and Melphalan may cause a minor interaction that can limit clinical effects when taken with Enoxacin and Enoxacin (Compound) resembles Trovafloxacin (Compound)
Chlorambucil (Compound) treats breast cancer (Disease) and breast cancer (Disease) is treated by Paclitaxel (Compound) and Paclitaxel may cause a minor interaction that can limit clinical effects when taken with Trovafloxacin
Chlorambucil (Compound) treats hematologic cancer (Disease) and hematologic cancer (Disease) is associated with TOP2A (Gene) and TOP2A (Gene) is bound by Trovafloxacin (Compound)