DDInter458 DDInter897
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus _Beauveria nivea_. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to [zoledronic acid], [minodronic acid], and [risedronic acid].[A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs. Ibandronate was granted FDA approval on 16 May 2003.
Cyclosporine {u} (Compound) causes {v} (Side Effect) Pain
Pain {u} (Side Effect) is caused by {v} (Compound) Ibandronate
Cyclosporine {u} (Compound) causes {v} (Side Effect) Pain
Pain {u} (Side Effect) is caused by {v} (Compound) Alendronic acid
Alendronic acid {u} (Compound) resembles {v} (Compound) Ibandronate
Cyclosporine {u} (Compound) causes {v} (Side Effect) Deafness
Deafness {u} (Side Effect) is caused by {v} (Compound) Vancomycin
Vancomycin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ibandronate
Cyclosporine {u} (Compound) causes {v} (Side Effect) Migraine
Migraine {u} (Side Effect) is caused by {v} (Compound) Thalidomide
Thalidomide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ibandronate
Cyclosporine {u} (Compound) causes {v} (Side Effect) Tooth disorder
Tooth disorder {u} (Side Effect) is caused by {v} (Compound) Risedronic acid
Risedronic acid {u} (Compound) resembles {v} (Compound) Ibandronate
Cyclosporine {u} (Compound) upregulates {v} (Gene) CNPY3
CNPY3 {u} (Gene) is upregulated by {v} (Compound) Alendronic acid
Alendronic acid {u} (Compound) resembles {v} (Compound) Ibandronate
Cyclosporine {u} (Compound) causes {v} (Side Effect) Feeling hot
Feeling hot {u} (Side Effect) is caused by {v} (Compound) Iohexol
Iohexol {u} may lead to a major life threatening interaction when taken with {v} Ibandronate
Cyclosporine {u} (Compound) downregulates {v} (Gene) RGS2
RGS2 {u} (Gene) is upregulated by {v} (Compound) Alendronic acid
Alendronic acid {u} (Compound) resembles {v} (Compound) Ibandronate
Cyclosporine {u} (Compound) upregulates {v} (Gene) CNPY3
CNPY3 {u} (Gene) is upregulated by {v} (Compound) Flurbiprofen
Flurbiprofen {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ibandronate
Cyclosporine {u} (Compound) upregulates {v} (Gene) RRP12
RRP12 {u} (Gene) is downregulated by {v} (Compound) Alendronic acid
Alendronic acid {u} (Compound) resembles {v} (Compound) Ibandronate
Cyclosporine (Compound) causes Pain (Side Effect) and Pain (Side Effect) is caused by Ibandronate (Compound)
Cyclosporine (Compound) causes Pain (Side Effect) and Pain (Side Effect) is caused by Alendronic acid (Compound) and Alendronic acid (Compound) resembles Ibandronate (Compound)
Cyclosporine (Compound) causes Deafness (Side Effect) and Deafness (Side Effect) is caused by Vancomycin (Compound) and Vancomycin may cause a moderate interaction that could exacerbate diseases when taken with Ibandronate
Cyclosporine (Compound) causes Migraine (Side Effect) and Migraine (Side Effect) is caused by Thalidomide (Compound) and Thalidomide may cause a moderate interaction that could exacerbate diseases when taken with Ibandronate
Cyclosporine (Compound) causes Tooth disorder (Side Effect) and Tooth disorder (Side Effect) is caused by Risedronic acid (Compound) and Risedronic acid (Compound) resembles Ibandronate (Compound)
Cyclosporine (Compound) upregulates CNPY3 (Gene) and CNPY3 (Gene) is upregulated by Alendronic acid (Compound) and Alendronic acid (Compound) resembles Ibandronate (Compound)
Cyclosporine (Compound) causes Feeling hot (Side Effect) and Feeling hot (Side Effect) is caused by Iohexol (Compound) and Iohexol may lead to a major life threatening interaction when taken with Ibandronate
Cyclosporine (Compound) downregulates RGS2 (Gene) and RGS2 (Gene) is upregulated by Alendronic acid (Compound) and Alendronic acid (Compound) resembles Ibandronate (Compound)
Cyclosporine (Compound) upregulates CNPY3 (Gene) and CNPY3 (Gene) is upregulated by Flurbiprofen (Compound) and Flurbiprofen may cause a moderate interaction that could exacerbate diseases when taken with Ibandronate
Cyclosporine (Compound) upregulates RRP12 (Gene) and RRP12 (Gene) is downregulated by Alendronic acid (Compound) and Alendronic acid (Compound) resembles Ibandronate (Compound)