DDInter940 DDInter1759
Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas that promotes glucose metabolism. Insulin is released from the pancreas following a meal to promote the uptake of glucose from the blood into internal organs and tissues such as the liver, fat cells, and skeletal muscle. Absorption of glucose into cells allows for its transformation into glycogen or fat for storage. Insulin also inhibits hepatic glucose production, enhances protein synthesis, and inhibits lipolysis and proteolysis among many other functions. Insulin is an important treatment in the management of Type 1 Diabetes (T1D) which is caused by an autoimmune reaction that destroys the beta cells of the pancreas, resulting in the body not being able to
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arterial blood pressure.[A1489,A1490] Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects.
Insulin lispro {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Azilsartan medoxomil
Azilsartan medoxomil {u} (Compound) resembles {v} (Compound) Telmisartan
Insulin lispro {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Azilsartan medoxomil
Azilsartan medoxomil {u} (Compound) resembles {v} (Compound) Candesartan
Candesartan {u} (Compound) resembles {v} (Compound) Telmisartan
Insulin lispro {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Losartan
Losartan {u} (Compound) resembles {v} (Compound) Candesartan
Candesartan {u} (Compound) resembles {v} (Compound) Telmisartan
Insulin lispro {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Empagliflozin
Empagliflozin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Azilsartan medoxomil
Azilsartan medoxomil {u} (Compound) resembles {v} (Compound) Telmisartan
Insulin lispro {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dapagliflozin
Dapagliflozin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Azilsartan medoxomil
Azilsartan medoxomil {u} (Compound) resembles {v} (Compound) Telmisartan
Insulin lispro {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Azilsartan medoxomil
Azilsartan medoxomil {u} (Compound) binds {v} (Gene) AGTR1
AGTR1 {u} (Gene) is bound by {v} (Compound) Telmisartan
Insulin lispro {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Losartan
Losartan {u} (Compound) treats {v} (Disease) hypertension
hypertension {u} (Disease) is treated by {v} (Compound) Telmisartan
Insulin lispro {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Azilsartan medoxomil
Azilsartan medoxomil {u} (Compound) causes {v} (Side Effect) Rash
Rash {u} (Side Effect) is caused by {v} (Compound) Telmisartan
Insulin lispro {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Losartan
Losartan {u} (Compound) is included by {v} (Pharmacologic Class) Angiotensin 2 Receptor Antagonists
Angiotensin 2 Receptor Antagonists {u} (Pharmacologic Class) includes {v} (Compound) Telmisartan
Insulin lispro {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Triamcinolone
Triamcinolone {u} (Compound) upregulates {v} (Gene) PPARG
PPARG {u} (Gene) is bound by {v} (Compound) Telmisartan
Insulin lispro may cause a moderate interaction that could exacerbate diseases when taken with Azilsartan medoxomil and Azilsartan medoxomil (Compound) resembles Telmisartan (Compound)
Insulin lispro may cause a moderate interaction that could exacerbate diseases when taken with Azilsartan medoxomil and Azilsartan medoxomil (Compound) resembles Candesartan (Compound) and Candesartan (Compound) resembles Telmisartan (Compound)
Insulin lispro may cause a moderate interaction that could exacerbate diseases when taken with Losartan and Losartan (Compound) resembles Candesartan (Compound) and Candesartan (Compound) resembles Telmisartan (Compound)
Insulin lispro may cause a moderate interaction that could exacerbate diseases when taken with Empagliflozin and Empagliflozin may cause a moderate interaction that could exacerbate diseases when taken with Azilsartan medoxomil and Azilsartan medoxomil (Compound) resembles Telmisartan (Compound)
Insulin lispro may cause a moderate interaction that could exacerbate diseases when taken with Dapagliflozin and Dapagliflozin may cause a moderate interaction that could exacerbate diseases when taken with Azilsartan medoxomil and Azilsartan medoxomil (Compound) resembles Telmisartan (Compound)
Insulin lispro may cause a moderate interaction that could exacerbate diseases when taken with Azilsartan medoxomil and Azilsartan medoxomil (Compound) binds AGTR1 (Gene) and AGTR1 (Gene) is bound by Telmisartan (Compound)
Insulin lispro may cause a moderate interaction that could exacerbate diseases when taken with Losartan and Losartan (Compound) treats hypertension (Disease) and hypertension (Disease) is treated by Telmisartan (Compound)
Insulin lispro may cause a moderate interaction that could exacerbate diseases when taken with Azilsartan medoxomil and Azilsartan medoxomil (Compound) causes Rash (Side Effect) and Rash (Side Effect) is caused by Telmisartan (Compound)
Insulin lispro may cause a moderate interaction that could exacerbate diseases when taken with Losartan and Losartan (Compound) is included by Angiotensin 2 Receptor Antagonists (Pharmacologic Class) and Angiotensin 2 Receptor Antagonists (Pharmacologic Class) includes Telmisartan (Compound)
Insulin lispro may cause a moderate interaction that could exacerbate diseases when taken with Triamcinolone and Triamcinolone (Compound) upregulates PPARG (Gene) and PPARG (Gene) is bound by Telmisartan (Compound)