DDInter103 DDInter1625
Equine anti-thymocyte globulin is composed of purified gamma globulin containing primarily IgG against human thymus lymphocytes. It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen. The result is polyclonal IgG that is then purified from the horse's serum to produce a usable drug product that can be used for immunosuppression. Although the exact mechanism of action is unknown, equine anti-thymocyte globulin targets a variety of immune system proteins including lymphocyte surface proteins, granulocytes, platelets, bone marrow cells, and other cell types. Equine ATG is currently indicated for the suppression of the immune system to prevent renal transplant rejection and in the treatment of aplastic anemia. Induction of T cell apoptosis and resulting T-cell lymphopenia found in vivo is credited for
Rubella virus vaccine is a live attenuated virus vaccine for active immunization against rubella (German measles) that is subcutaneously administered. It is prepared from RA 27/3 strain of live attenuated rubella virus. Rubella is a common childhood disease, caused by rubella virus (togavirus).
Antilymphocyte immunoglobulin (horse) {u} may cause a minor interaction that can limit clinical effects when taken with {v} Zinc gluconate
Antilymphocyte immunoglobulin (horse) {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ustekinumab
Antilymphocyte immunoglobulin (horse) {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Canakinumab
Antilymphocyte immunoglobulin (horse) {u} may lead to a major life threatening interaction when taken with {v} Measles virus vaccine live attenuated
Antilymphocyte immunoglobulin (horse) {u} may lead to a major life threatening interaction when taken with {v} Cladribine
Antilymphocyte immunoglobulin (horse) may cause a minor interaction that can limit clinical effects when taken with Zinc gluconate
Antilymphocyte immunoglobulin (horse) may cause a moderate interaction that could exacerbate diseases when taken with Ustekinumab
Antilymphocyte immunoglobulin (horse) may cause a moderate interaction that could exacerbate diseases when taken with Canakinumab
Antilymphocyte immunoglobulin (horse) may lead to a major life threatening interaction when taken with Measles virus vaccine live attenuated
Antilymphocyte immunoglobulin (horse) may lead to a major life threatening interaction when taken with Cladribine