DDInter1340 DDInter696
Originally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class, and its approval was followed by the formulation of many other proton pump inhibitor drugs. Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults [FDA label].
Ethotoin is a hydantoin derivative and anticonvulsant. Ethotoin exerts an antiepileptic effect without causing general central nervous system depression. The mechanism of action is probably very similar to that of phenytoin. The latter drug appears to stabilize rather than to raise the normal seizure threshold, and to prevent the spread of seizure activity rather than to abolish the primary focus of seizure discharges. Ethotoin is no longer commonly used.
Omeprazole {u} (Compound) binds {v} (Gene) CYP2C19
CYP2C19 {u} (Gene) is bound by {v} (Compound) Ethotoin
Omeprazole {u} (Compound) causes {v} (Side Effect) Chest pain
Chest pain {u} (Side Effect) is caused by {v} (Compound) Ethotoin
Omeprazole {u} (Compound) binds {v} (Gene) CYP2C19
CYP2C19 {u} (Gene) is bound by {v} (Compound) Primidone
Primidone {u} (Compound) resembles {v} (Compound) Ethotoin
Omeprazole {u} (Compound) causes {v} (Side Effect) Chest pain
Chest pain {u} (Side Effect) is caused by {v} (Compound) Mycophenolic acid
Mycophenolic acid {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ethotoin
Omeprazole {u} (Compound) causes {v} (Side Effect) Dizziness
Dizziness {u} (Side Effect) is caused by {v} (Compound) Primidone
Primidone {u} (Compound) resembles {v} (Compound) Ethotoin
Omeprazole {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Tranylcypromine
Tranylcypromine {u} (Compound) resembles {v} (Compound) Ethotoin
Omeprazole {u} (Compound) causes {v} (Side Effect) Chest pain
Chest pain {u} (Side Effect) is caused by {v} (Compound) Lidocaine
Lidocaine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ethotoin
Omeprazole {u} (Compound) causes {v} (Side Effect) Lymphadenopathy
Lymphadenopathy {u} (Side Effect) is caused by {v} (Compound) Methotrexate
Methotrexate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ethotoin
Omeprazole {u} (Compound) binds {v} (Gene) CYP11A1
CYP11A1 {u} (Gene) is bound by {v} (Compound) Dexamethasone
Dexamethasone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ethotoin
Omeprazole {u} (Compound) causes {v} (Side Effect) Lymphadenopathy
Lymphadenopathy {u} (Side Effect) is caused by {v} (Compound) Acyclovir
Acyclovir {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ethotoin
Omeprazole (Compound) binds CYP2C19 (Gene) and CYP2C19 (Gene) is bound by Ethotoin (Compound)
Omeprazole (Compound) causes Chest pain (Side Effect) and Chest pain (Side Effect) is caused by Ethotoin (Compound)
Omeprazole (Compound) binds CYP2C19 (Gene) and CYP2C19 (Gene) is bound by Primidone (Compound) and Primidone (Compound) resembles Ethotoin (Compound)
Omeprazole (Compound) causes Chest pain (Side Effect) and Chest pain (Side Effect) is caused by Mycophenolic acid (Compound) and Mycophenolic acid may cause a minor interaction that can limit clinical effects when taken with Ethotoin
Omeprazole (Compound) causes Dizziness (Side Effect) and Dizziness (Side Effect) is caused by Primidone (Compound) and Primidone (Compound) resembles Ethotoin (Compound)
Omeprazole (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Tranylcypromine (Compound) and Tranylcypromine (Compound) resembles Ethotoin (Compound)
Omeprazole (Compound) causes Chest pain (Side Effect) and Chest pain (Side Effect) is caused by Lidocaine (Compound) and Lidocaine may cause a minor interaction that can limit clinical effects when taken with Ethotoin
Omeprazole (Compound) causes Lymphadenopathy (Side Effect) and Lymphadenopathy (Side Effect) is caused by Methotrexate (Compound) and Methotrexate may cause a moderate interaction that could exacerbate diseases when taken with Ethotoin
Omeprazole (Compound) binds CYP11A1 (Gene) and CYP11A1 (Gene) is bound by Dexamethasone (Compound) and Dexamethasone may cause a moderate interaction that could exacerbate diseases when taken with Ethotoin
Omeprazole (Compound) causes Lymphadenopathy (Side Effect) and Lymphadenopathy (Side Effect) is caused by Acyclovir (Compound) and Acyclovir may cause a moderate interaction that could exacerbate diseases when taken with Ethotoin