DDInter790 DDInter1155
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of water from the body. Furosemide has a fast onset and short duration of action and has been used safely and effectively in both pediatric and adult patients. The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential. In addition to oral formulations, the solution for intravenous and intramuscular administration is also available, which is typically limited to patients who are unable to take oral medication or for patients in emergency clinical situations.
Mepyramine, or pyrilamine, targets the H1 receptor. It is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect. It has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered to be an unapproved prescription medication used for cough, cold, or allergic conditions.
Furosemide {u} (Compound) binds {v} (Gene) SLC22A5
SLC22A5 {u} (Gene) is bound by {v} (Compound) Mepyramine
Furosemide {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mepyramine
Furosemide {u} (Compound) binds {v} (Gene) SLC22A5
SLC22A5 {u} (Gene) is bound by {v} (Compound) Diphenhydramine
Diphenhydramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mepyramine
Furosemide {u} (Compound) resembles {v} (Compound) Bumetanide
Bumetanide {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mepyramine
Furosemide {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Aldesleukin
Aldesleukin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mepyramine
Furosemide {u} (Compound) treats {v} (Disease) coronary artery disease
coronary artery disease {u} (Disease) is treated by {v} (Compound) Losartan
Losartan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mepyramine
Furosemide {u} (Compound) treats {v} (Disease) coronary artery disease
coronary artery disease {u} (Disease) is palliated by {v} (Compound) Diltiazem
Diltiazem {u} (Compound) resembles {v} (Compound) Mepyramine
Furosemide {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Opium
Opium {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mepyramine
Furosemide {u} (Compound) treats {v} (Disease) dilated cardiomyopathy
dilated cardiomyopathy {u} (Disease) is associated with {v} (Gene) SLC22A5
SLC22A5 {u} (Gene) is bound by {v} (Compound) Mepyramine
Furosemide {u} (Compound) resembles {v} (Compound) Indapamide
Indapamide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Clidinium
Clidinium {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mepyramine
Furosemide (Compound) binds SLC22A5 (Gene) and SLC22A5 (Gene) is bound by Mepyramine (Compound)
Furosemide (Compound) resembles Indapamide (Compound) and Indapamide may cause a moderate interaction that could exacerbate diseases when taken with Mepyramine
Furosemide (Compound) binds SLC22A5 (Gene) and SLC22A5 (Gene) is bound by Diphenhydramine (Compound) and Diphenhydramine may cause a moderate interaction that could exacerbate diseases when taken with Mepyramine
Furosemide (Compound) resembles Bumetanide (Compound) and Bumetanide (Compound) resembles Indapamide (Compound) and Indapamide may cause a moderate interaction that could exacerbate diseases when taken with Mepyramine
Furosemide (Compound) resembles Indapamide (Compound) and Indapamide may cause a moderate interaction that could exacerbate diseases when taken with Aldesleukin and Aldesleukin may cause a moderate interaction that could exacerbate diseases when taken with Mepyramine
Furosemide (Compound) treats coronary artery disease (Disease) and coronary artery disease (Disease) is treated by Losartan (Compound) and Losartan may cause a moderate interaction that could exacerbate diseases when taken with Mepyramine
Furosemide (Compound) treats coronary artery disease (Disease) and coronary artery disease (Disease) is palliated by Diltiazem (Compound) and Diltiazem (Compound) resembles Mepyramine (Compound)
Furosemide (Compound) resembles Indapamide (Compound) and Indapamide may cause a moderate interaction that could exacerbate diseases when taken with Opium and Opium may cause a moderate interaction that could exacerbate diseases when taken with Mepyramine
Furosemide (Compound) treats dilated cardiomyopathy (Disease) and dilated cardiomyopathy (Disease) is associated with SLC22A5 (Gene) and SLC22A5 (Gene) is bound by Mepyramine (Compound)
Furosemide (Compound) resembles Indapamide (Compound) and Indapamide may cause a minor interaction that can limit clinical effects when taken with Clidinium and Clidinium may cause a moderate interaction that could exacerbate diseases when taken with Mepyramine