DDInter1610 DDInter666
Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type. Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase.
Eribulin is a microtubule inhibitor indicated for the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic disease. Eribulin was isolated from the marine sponge Halichondria okadai. Eribulin is also being investigated for use in the treatment of advanced solid tumors .
Rivastigmine {u} (Compound) upregulates {v} (Gene) GHR
GHR {u} (Gene) is downregulated by {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Eribulin
Rivastigmine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is associated with {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Eribulin
Rivastigmine {u} (Compound) upregulates {v} (Gene) GHR
GHR {u} (Gene) is upregulated by {v} (Compound) Auranofin
Auranofin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eribulin
Rivastigmine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Verapamil
Verapamil {u} may cause a minor interaction that can limit clinical effects when taken with {v} Eribulin
Rivastigmine {u} (Compound) upregulates {v} (Gene) FGFR2
FGFR2 {u} (Gene) is associated with {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Eribulin
Rivastigmine {u} (Compound) binds {v} (Gene) BCHE
BCHE {u} (Gene) is bound by {v} (Compound) Chlorpromazine
Chlorpromazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eribulin
Rivastigmine {u} (Compound) upregulates {v} (Gene) FGFR2
FGFR2 {u} (Gene) is bound by {v} (Compound) Sunitinib
Sunitinib {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eribulin
Rivastigmine {u} (Compound) downregulates {v} (Gene) CDC20
CDC20 {u} (Gene) is upregulated by {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Eribulin
Rivastigmine {u} (Compound) upregulates {v} (Gene) FGFR2
FGFR2 {u} (Gene) is bound by {v} (Compound) and {u} (Gene) is downregulated by {v} (Compound) Pazopanib
Pazopanib {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eribulin
Rivastigmine {u} (Compound) upregulates {v} (Gene) GHR
GHR {u} (Gene) is upregulated by {v} (Compound) Sparfloxacin
Sparfloxacin {u} may lead to a major life threatening interaction when taken with {v} Eribulin
Rivastigmine (Compound) upregulates GHR (Gene) and GHR (Gene) is downregulated by breast cancer (Disease) and breast cancer (Disease) is treated by Eribulin (Compound)
Rivastigmine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is associated with breast cancer (Disease) and breast cancer (Disease) is treated by Eribulin (Compound)
Rivastigmine (Compound) upregulates GHR (Gene) and GHR (Gene) is upregulated by Auranofin (Compound) and Auranofin may cause a moderate interaction that could exacerbate diseases when taken with Eribulin
Rivastigmine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Verapamil (Compound) and Verapamil may cause a minor interaction that can limit clinical effects when taken with Eribulin
Rivastigmine (Compound) upregulates FGFR2 (Gene) and FGFR2 (Gene) is associated with breast cancer (Disease) and breast cancer (Disease) is treated by Eribulin (Compound)
Rivastigmine (Compound) binds BCHE (Gene) and BCHE (Gene) is bound by Chlorpromazine (Compound) and Chlorpromazine may cause a moderate interaction that could exacerbate diseases when taken with Eribulin
Rivastigmine (Compound) upregulates FGFR2 (Gene) and FGFR2 (Gene) is bound by Sunitinib (Compound) and Sunitinib may cause a moderate interaction that could exacerbate diseases when taken with Eribulin
Rivastigmine (Compound) downregulates CDC20 (Gene) and CDC20 (Gene) is upregulated by breast cancer (Disease) and breast cancer (Disease) is treated by Eribulin (Compound)
Rivastigmine (Compound) upregulates FGFR2 (Gene) and FGFR2 (Gene) is bound by Pazopanib (Compound) and FGFR2 (Gene) is downregulated by Pazopanib (Compound) and Pazopanib may cause a moderate interaction that could exacerbate diseases when taken with Eribulin
Rivastigmine (Compound) upregulates GHR (Gene) and GHR (Gene) is upregulated by Sparfloxacin (Compound) and Sparfloxacin may lead to a major life threatening interaction when taken with Eribulin