DDInter1867 DDInter1400
A phenothiazine used as an antipsychotic agent and as an antiemetic.
Pazopanib is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. It is developed by GlaxoSmithKline and was FDA approved on October 19, 2009.
Triflupromazine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Pazopanib
Triflupromazine {u} (Compound) downregulates {v} (Gene) MRPS16
MRPS16 {u} (Gene) is upregulated by {v} (Compound) Pazopanib
Triflupromazine {u} (Compound) resembles {v} (Compound) Perphenazine
Perphenazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pazopanib
Triflupromazine {u} (Compound) resembles {v} (Compound) Thioridazine
Thioridazine {u} may lead to a major life threatening interaction when taken with {v} Pazopanib
Triflupromazine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is downregulated by {v} (Disease) and {u} (Disease) associated with {v} (Gene) kidney cancer
kidney cancer {u} (Disease) is treated by {v} (Compound) Pazopanib
Triflupromazine {u} (Compound) downregulates {v} (Gene) MRPS16
MRPS16 {u} (Gene) is regulated by {v} (Gene) RIOK2
RIOK2 {u} (Gene) is bound by {v} (Compound) Pazopanib
Triflupromazine {u} (Compound) resembles {v} (Compound) Perphenazine
Perphenazine {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Pazopanib
Triflupromazine {u} (Compound) resembles {v} (Compound) Pipotiazine
Pipotiazine {u} (Compound) resembles {v} (Compound) Methotrimeprazine
Methotrimeprazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pazopanib
Triflupromazine {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) regulates {v} (Gene) FGFR3
FGFR3 {u} (Gene) is bound by {v} (Compound) Pazopanib
Triflupromazine {u} (Compound) downregulates {v} (Gene) POLE2
POLE2 {u} (Gene) is regulated by {v} (Gene) MNAT1
MNAT1 {u} (Gene) is upregulated by {v} (Compound) Pazopanib
Triflupromazine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Pazopanib (Compound)
Triflupromazine (Compound) downregulates MRPS16 (Gene) and MRPS16 (Gene) is upregulated by Pazopanib (Compound)
Triflupromazine (Compound) resembles Perphenazine (Compound) and Perphenazine may cause a moderate interaction that could exacerbate diseases when taken with Pazopanib
Triflupromazine (Compound) resembles Thioridazine (Compound) and Thioridazine may lead to a major life threatening interaction when taken with Pazopanib
Triflupromazine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is downregulated by kidney cancer (Disease) and ABCB1 (Disease) associated with kidney cancer (Gene) and kidney cancer (Disease) is treated by Pazopanib (Compound)
Triflupromazine (Compound) downregulates MRPS16 (Gene) and MRPS16 (Gene) is regulated by RIOK2 (Gene) and RIOK2 (Gene) is bound by Pazopanib (Compound)
Triflupromazine (Compound) resembles Perphenazine (Compound) and Perphenazine (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Pazopanib (Compound)
Triflupromazine (Compound) resembles Pipotiazine (Compound) and Pipotiazine (Compound) resembles Methotrimeprazine (Compound) and Methotrimeprazine may cause a moderate interaction that could exacerbate diseases when taken with Pazopanib
Triflupromazine (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) regulates FGFR3 (Gene) and FGFR3 (Gene) is bound by Pazopanib (Compound)
Triflupromazine (Compound) downregulates POLE2 (Gene) and POLE2 (Gene) is regulated by MNAT1 (Gene) and MNAT1 (Gene) is upregulated by Pazopanib (Compound)