DDInter947 DDInter1619
Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interferon beta.
Ropinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], . It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. In 2005, it was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome . In 2008, the extended-release capsules of ropinirole were approved, allowing for less frequent dosing, therefore increased compliance, and offering a similar side effect profile and efficacy to previous formulations of ropinirole .
Interferon beta-1a {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Pasireotide
Pasireotide {u} (Compound) causes {v} (Side Effect) Abdominal pain
Abdominal pain {u} (Side Effect) is caused by {v} (Compound) Ropinirole
Interferon beta-1a {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Isoniazid
Isoniazid {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Ropinirole
Interferon beta-1a {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Bromfenac
Bromfenac {u} (Compound) upregulates {v} (Gene) MCOLN1
MCOLN1 {u} (Gene) is upregulated by {v} (Compound) Ropinirole
Interferon beta-1a {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Bromfenac
Bromfenac {u} (Compound) downregulates {v} (Gene) PPP2R5E
PPP2R5E {u} (Gene) is downregulated by {v} (Compound) Ropinirole
Interferon beta-1a {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Afatinib
Afatinib {u} (Compound) downregulates {v} (Gene) RRP8
RRP8 {u} (Gene) is upregulated by {v} (Compound) Ropinirole
Interferon beta-1a {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Afatinib
Afatinib {u} (Compound) upregulates {v} (Gene) UBQLN2
UBQLN2 {u} (Gene) is downregulated by {v} (Compound) Ropinirole
Interferon beta-1a {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Carbamazepine
Carbamazepine {u} (Compound) palliates {v} (Disease) restless legs syndrome
restless legs syndrome {u} (Disease) is palliated by {v} (Compound) Ropinirole
Interferon beta-1a {u} may lead to a major life threatening interaction when taken with {v} Tramadol
Tramadol {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Ropinirole
Interferon beta-1a {u} may lead to a major life threatening interaction when taken with {v} Zidovudine
Zidovudine {u} (Compound) downregulates {v} (Gene) RBM34
RBM34 {u} (Gene) is downregulated by {v} (Compound) Ropinirole
Interferon beta-1a {u} may lead to a major life threatening interaction when taken with {v} Tramadol
Tramadol {u} (Compound) palliates {v} (Disease) restless legs syndrome
restless legs syndrome {u} (Disease) is palliated by {v} (Compound) Ropinirole
Interferon beta-1a may cause a moderate interaction that could exacerbate diseases when taken with Pasireotide and Pasireotide (Compound) causes Abdominal pain (Side Effect) and Abdominal pain (Side Effect) is caused by Ropinirole (Compound)
Interferon beta-1a may cause a moderate interaction that could exacerbate diseases when taken with Isoniazid and Isoniazid (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Ropinirole (Compound)
Interferon beta-1a may cause a moderate interaction that could exacerbate diseases when taken with Bromfenac and Bromfenac (Compound) upregulates MCOLN1 (Gene) and MCOLN1 (Gene) is upregulated by Ropinirole (Compound)
Interferon beta-1a may cause a moderate interaction that could exacerbate diseases when taken with Bromfenac and Bromfenac (Compound) downregulates PPP2R5E (Gene) and PPP2R5E (Gene) is downregulated by Ropinirole (Compound)
Interferon beta-1a may cause a moderate interaction that could exacerbate diseases when taken with Afatinib and Afatinib (Compound) downregulates RRP8 (Gene) and RRP8 (Gene) is upregulated by Ropinirole (Compound)
Interferon beta-1a may cause a moderate interaction that could exacerbate diseases when taken with Afatinib and Afatinib (Compound) upregulates UBQLN2 (Gene) and UBQLN2 (Gene) is downregulated by Ropinirole (Compound)
Interferon beta-1a may cause a moderate interaction that could exacerbate diseases when taken with Carbamazepine and Carbamazepine (Compound) palliates restless legs syndrome (Disease) and restless legs syndrome (Disease) is palliated by Ropinirole (Compound)
Interferon beta-1a may lead to a major life threatening interaction when taken with Tramadol and Tramadol (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Ropinirole (Compound)
Interferon beta-1a may lead to a major life threatening interaction when taken with Zidovudine and Zidovudine (Compound) downregulates RBM34 (Gene) and RBM34 (Gene) is downregulated by Ropinirole (Compound)
Interferon beta-1a may lead to a major life threatening interaction when taken with Tramadol and Tramadol (Compound) palliates restless legs syndrome (Disease) and restless legs syndrome (Disease) is palliated by Ropinirole (Compound)