DDInter1160 DDInter1544
The 3-methyl ether of ethinyl estradiol. It must be demethylated to be biologically active. It is used as the estrogen component of many combination ORAL contraceptives.
Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties. The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies. Prucalopride was developed by Shire Development LLC and approved for use in Europe in 2009, in Canada on December 7, 2011 and by the FDA on December 17, 2018.
Mestranol {u} (Compound) resembles {v} (Compound) Norethisterone
Mestranol {u} (Compound) resembles {v} (Compound) Ethinylestradiol
Mestranol {u} (Compound) binds {v} (Gene) ESR1
Mestranol {u} (Compound) upregulates {v} (Gene) UBQLN2
Mestranol {u} (Compound) is included by {v} (Pharmacologic Class) Estrogen Receptor Agonists
Mestranol {u} (Compound) downregulates {v} (Gene) YBX3
Mestranol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Cimetidine
Mestranol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Hyaluronidase
Mestranol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methylprednisolone
Mestranol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sarilumab
Mestranol (Compound) resembles Norethisterone (Compound)
Mestranol (Compound) resembles Ethinylestradiol (Compound)
Mestranol (Compound) binds ESR1 (Gene)
Mestranol (Compound) upregulates UBQLN2 (Gene)
Mestranol (Compound) is included by Estrogen Receptor Agonists (Pharmacologic Class)
Mestranol (Compound) downregulates YBX3 (Gene)
Mestranol may cause a minor interaction that can limit clinical effects when taken with Cimetidine
Mestranol may cause a minor interaction that can limit clinical effects when taken with Hyaluronidase
Mestranol may cause a moderate interaction that could exacerbate diseases when taken with Methylprednisolone
Mestranol may cause a moderate interaction that could exacerbate diseases when taken with Sarilumab