DDInter1662 DDInter1526
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before beneficial effects are noticed. Sertraline displays enhanced safety or tolerability than other classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and other undesirable effects.[A1846,A187075,T28]
An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
Sertraline {u} (Compound) downregulates {v} (Gene) DLD
DLD {u} (Gene) is downregulated by {v} (Compound) Procarbazine
Sertraline {u} (Compound) causes {v} (Side Effect) Headache
Headache {u} (Side Effect) is caused by {v} (Compound) Procarbazine
Sertraline {u} (Compound) resembles {v} (Compound) Maprotiline
Maprotiline {u} may lead to a major life threatening interaction when taken with {v} Procarbazine
Sertraline {u} (Compound) downregulates {v} (Gene) DLD
DLD {u} (Gene) regulates {v} (Gene) MOK
MOK {u} (Gene) is upregulated by {v} (Compound) Procarbazine
Sertraline {u} (Compound) causes {v} (Side Effect) Headache
Headache {u} (Side Effect) is caused by {v} (Compound) Atenolol
Atenolol {u} (Compound) resembles {v} (Compound) Procarbazine
Sertraline {u} (Compound) causes {v} (Side Effect) Amenorrhoea
Amenorrhoea {u} (Side Effect) is caused by {v} (Compound) Metoclopramide
Metoclopramide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Procarbazine
Sertraline {u} (Compound) causes {v} (Side Effect) Sweating increased
Sweating increased {u} (Side Effect) is caused by {v} (Compound) Lomefloxacin
Lomefloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Procarbazine
Sertraline {u} (Compound) causes {v} (Side Effect) Hyporeflexia
Hyporeflexia {u} (Side Effect) is caused by {v} (Compound) Chlorpheniramine
Chlorpheniramine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Procarbazine
Sertraline {u} (Compound) causes {v} (Side Effect) Haemorrhagic disorder
Haemorrhagic disorder {u} (Side Effect) is caused by {v} (Compound) Trazodone
Trazodone {u} may lead to a major life threatening interaction when taken with {v} Procarbazine
Sertraline {u} (Compound) causes {v} (Side Effect) Nocturia
Nocturia {u} (Side Effect) is caused by {v} (Compound) Sparfloxacin
Sparfloxacin {u} may cause a minor interaction that can limit clinical effects when taken with {v} Procarbazine
Sertraline (Compound) downregulates DLD (Gene) and DLD (Gene) is downregulated by Procarbazine (Compound)
Sertraline (Compound) causes Headache (Side Effect) and Headache (Side Effect) is caused by Procarbazine (Compound)
Sertraline (Compound) resembles Maprotiline (Compound) and Maprotiline may lead to a major life threatening interaction when taken with Procarbazine
Sertraline (Compound) downregulates DLD (Gene) and DLD (Gene) regulates MOK (Gene) and MOK (Gene) is upregulated by Procarbazine (Compound)
Sertraline (Compound) causes Headache (Side Effect) and Headache (Side Effect) is caused by Atenolol (Compound) and Atenolol (Compound) resembles Procarbazine (Compound)
Sertraline (Compound) causes Amenorrhoea (Side Effect) and Amenorrhoea (Side Effect) is caused by Metoclopramide (Compound) and Metoclopramide may cause a moderate interaction that could exacerbate diseases when taken with Procarbazine
Sertraline (Compound) causes Sweating increased (Side Effect) and Sweating increased (Side Effect) is caused by Lomefloxacin (Compound) and Lomefloxacin may cause a minor interaction that can limit clinical effects when taken with Procarbazine
Sertraline (Compound) causes Hyporeflexia (Side Effect) and Hyporeflexia (Side Effect) is caused by Chlorpheniramine (Compound) and Chlorpheniramine may cause a moderate interaction that could exacerbate diseases when taken with Procarbazine
Sertraline (Compound) causes Haemorrhagic disorder (Side Effect) and Haemorrhagic disorder (Side Effect) is caused by Trazodone (Compound) and Trazodone may lead to a major life threatening interaction when taken with Procarbazine
Sertraline (Compound) causes Nocturia (Side Effect) and Nocturia (Side Effect) is caused by Sparfloxacin (Compound) and Sparfloxacin may cause a minor interaction that can limit clinical effects when taken with Procarbazine