DDInter1759 DDInter1763
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arterial blood pressure.[A1489,A1490] Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects.
Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). It was developed by Wyeth Pharmaceuticals under the trade name Torisel. Temsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007.
Telmisartan {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Temsirolimus
Telmisartan {u} (Compound) causes {v} (Side Effect) Gastritis
Gastritis {u} (Side Effect) is caused by {v} (Compound) Temsirolimus
Telmisartan {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Tacrolimus
Tacrolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Telmisartan {u} (Compound) causes {v} (Side Effect) Gastritis
Gastritis {u} (Side Effect) is caused by {v} (Compound) Everolimus
Everolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Telmisartan {u} (Compound) resembles {v} (Compound) Candesartan
Candesartan {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Temsirolimus
Telmisartan {u} (Compound) resembles {v} (Compound) Azilsartan medoxomil
Azilsartan medoxomil {u} (Compound) causes {v} (Side Effect) Angiopathy
Angiopathy {u} (Side Effect) is caused by {v} (Compound) Temsirolimus
Telmisartan {u} (Compound) resembles {v} (Compound) Candesartan
Candesartan {u} (Compound) downregulates {v} (Gene) NVL
NVL {u} (Gene) is upregulated by {v} (Compound) Temsirolimus
Telmisartan {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is downregulated by {v} (Disease) and {u} (Disease) associated with {v} (Gene) kidney cancer
kidney cancer {u} (Disease) is treated by {v} (Compound) Temsirolimus
Telmisartan {u} (Compound) resembles {v} (Compound) Azilsartan medoxomil
Azilsartan medoxomil {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Temsirolimus
Telmisartan {u} (Compound) resembles {v} (Compound) Candesartan
Candesartan {u} (Compound) upregulates {v} (Gene) TATDN2
TATDN2 {u} (Gene) is downregulated by {v} (Compound) Temsirolimus
Telmisartan (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Temsirolimus (Compound)
Telmisartan (Compound) causes Gastritis (Side Effect) and Gastritis (Side Effect) is caused by Temsirolimus (Compound)
Telmisartan (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Tacrolimus (Compound) and Tacrolimus (Compound) resembles Temsirolimus (Compound)
Telmisartan (Compound) causes Gastritis (Side Effect) and Gastritis (Side Effect) is caused by Everolimus (Compound) and Everolimus (Compound) resembles Temsirolimus (Compound)
Telmisartan (Compound) resembles Candesartan (Compound) and Candesartan (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Temsirolimus (Compound)
Telmisartan (Compound) resembles Azilsartan medoxomil (Compound) and Azilsartan medoxomil (Compound) causes Angiopathy (Side Effect) and Angiopathy (Side Effect) is caused by Temsirolimus (Compound)
Telmisartan (Compound) resembles Candesartan (Compound) and Candesartan (Compound) downregulates NVL (Gene) and NVL (Gene) is upregulated by Temsirolimus (Compound)
Telmisartan (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is downregulated by kidney cancer (Disease) and ABCB1 (Disease) associated with kidney cancer (Gene) and kidney cancer (Disease) is treated by Temsirolimus (Compound)
Telmisartan (Compound) resembles Azilsartan medoxomil (Compound) and Azilsartan medoxomil may cause a moderate interaction that could exacerbate diseases when taken with Sirolimus and Sirolimus (Compound) resembles Temsirolimus (Compound)
Telmisartan (Compound) resembles Candesartan (Compound) and Candesartan (Compound) upregulates TATDN2 (Gene) and TATDN2 (Gene) is downregulated by Temsirolimus (Compound)