DDInter533 DDInter1254
A commonly used x-ray contrast medium. As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree of cyclooxygenase-2 selectivity (COX-2), nabumetone still produces significant adverse effects in the GI tract.[label,A178903] The molecule itself is a pro-drug with its 6-methoxy-2-naphthylacetic acid (6-MNA) metabolite acting as a potent COX inhibitor similar in structure to [naproxen]. Nabumetone was developed by Smithkline Beecham under the trade name Relafen and first received FDA approval in December, 1991.
Diatrizoate {u} (Compound) causes {v} (Side Effect) Pruritus
Pruritus {u} (Side Effect) is caused by {v} (Compound) Nabumetone
Diatrizoate {u} (Compound) causes {v} (Side Effect) Pruritus
Pruritus {u} (Side Effect) is caused by {v} (Compound) Naproxen
Naproxen {u} (Compound) resembles {v} (Compound) Nabumetone
Diatrizoate {u} (Compound) causes {v} (Side Effect) Agitation
Agitation {u} (Side Effect) is caused by {v} (Compound) Melatonin
Melatonin {u} (Compound) resembles {v} (Compound) Nabumetone
Diatrizoate {u} (Compound) causes {v} (Side Effect) Azotaemia
Azotaemia {u} (Side Effect) is caused by {v} (Compound) Vancomycin
Vancomycin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nabumetone
Diatrizoate {u} (Compound) resembles {v} (Compound) Iodipamide
Iodipamide {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Nabumetone
Diatrizoate {u} (Compound) causes {v} (Side Effect) Arrhythmia
Arrhythmia {u} (Side Effect) is caused by {v} (Compound) Ranitidine
Ranitidine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Nabumetone
Diatrizoate {u} (Compound) is included by {v} (Pharmacologic Class) X-Ray Contrast Activity
X-Ray Contrast Activity {u} (Pharmacologic Class) includes {v} (Compound) Iohexol
Iohexol {u} may lead to a major life threatening interaction when taken with {v} Nabumetone
Diatrizoate {u} (Compound) causes {v} (Side Effect) Nephrotic syndrome
Nephrotic syndrome {u} (Side Effect) is caused by {v} (Compound) Ticlopidine
Ticlopidine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nabumetone
Diatrizoate {u} (Compound) causes {v} (Side Effect) Nephrotic syndrome
Nephrotic syndrome {u} (Side Effect) is caused by {v} (Compound) Sirolimus
Sirolimus {u} may lead to a major life threatening interaction when taken with {v} Nabumetone
Diatrizoate (Compound) causes Pruritus (Side Effect) and Pruritus (Side Effect) is caused by Nabumetone (Compound)
Diatrizoate (Compound) causes Pruritus (Side Effect) and Pruritus (Side Effect) is caused by Naproxen (Compound) and Naproxen (Compound) resembles Nabumetone (Compound)
Diatrizoate (Compound) causes Agitation (Side Effect) and Agitation (Side Effect) is caused by Melatonin (Compound) and Melatonin (Compound) resembles Nabumetone (Compound)
Diatrizoate (Compound) causes Azotaemia (Side Effect) and Azotaemia (Side Effect) is caused by Vancomycin (Compound) and Vancomycin may cause a moderate interaction that could exacerbate diseases when taken with Nabumetone
Diatrizoate (Compound) resembles Iodipamide (Compound) and Iodipamide (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Nabumetone (Compound)
Diatrizoate (Compound) causes Arrhythmia (Side Effect) and Arrhythmia (Side Effect) is caused by Ranitidine (Compound) and Ranitidine may cause a minor interaction that can limit clinical effects when taken with Nabumetone
Diatrizoate (Compound) is included by X-Ray Contrast Activity (Pharmacologic Class) and X-Ray Contrast Activity (Pharmacologic Class) includes Iohexol (Compound) and Iohexol may lead to a major life threatening interaction when taken with Nabumetone
Diatrizoate (Compound) causes Nephrotic syndrome (Side Effect) and Nephrotic syndrome (Side Effect) is caused by Ticlopidine (Compound) and Ticlopidine may cause a moderate interaction that could exacerbate diseases when taken with Nabumetone
Diatrizoate (Compound) causes Nephrotic syndrome (Side Effect) and Nephrotic syndrome (Side Effect) is caused by Sirolimus (Compound) and Sirolimus may lead to a major life threatening interaction when taken with Nabumetone