DDInter458 DDInter666
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus _Beauveria nivea_. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
Eribulin is a microtubule inhibitor indicated for the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic disease. Eribulin was isolated from the marine sponge Halichondria okadai. Eribulin is also being investigated for use in the treatment of advanced solid tumors .
Cyclosporine {u} (Compound) downregulates {v} (Gene) TUBB4B
TUBB4B {u} (Gene) is bound by {v} (Compound) Eribulin
Cyclosporine {u} (Compound) downregulates {v} (Gene) TUBB4B
TUBB4B {u} (Gene) is bound by {v} (Compound) Paclitaxel
Paclitaxel {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eribulin
Cyclosporine {u} (Compound) downregulates {v} (Gene) PROS1
PROS1 {u} (Gene) is downregulated by {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Eribulin
Cyclosporine {u} (Compound) downregulates {v} (Gene) TUBB6
TUBB6 {u} (Gene) is regulated by {v} (Gene) TUBB2A
TUBB2A {u} (Gene) is bound by {v} (Compound) Eribulin
Cyclosporine {u} (Compound) upregulates {v} (Gene) INPP1
INPP1 {u} (Gene) is downregulated by {v} (Disease) breast cancer
breast cancer {u} (Disease) is treated by {v} (Compound) Eribulin
Cyclosporine {u} (Compound) downregulates {v} (Gene) PROS1
PROS1 {u} (Gene) is upregulated by {v} (Compound) Daunorubicin
Daunorubicin {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eribulin
Cyclosporine {u} (Compound) downregulates {v} (Gene) TUBB6
TUBB6 {u} (Gene) regulates {v} (Gene) TUBB3
TUBB3 {u} (Gene) is bound by {v} (Compound) Eribulin
Cyclosporine {u} (Compound) downregulates {v} (Gene) TUBB4B
TUBB4B {u} (Gene) is downregulated by {v} (Compound) Dasatinib
Dasatinib {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eribulin
Cyclosporine {u} (Compound) upregulates {v} (Gene) INPP1
INPP1 {u} (Gene) is upregulated by {v} (Compound) Bisacodyl
Bisacodyl {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eribulin
Cyclosporine {u} (Compound) downregulates {v} (Gene) TUBB6
TUBB6 {u} (Gene) is bound by {v} (Compound) and {u} (Gene) is upregulated by {v} (Compound) Paclitaxel
Paclitaxel {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eribulin
Cyclosporine (Compound) downregulates TUBB4B (Gene) and TUBB4B (Gene) is bound by Eribulin (Compound)
Cyclosporine (Compound) downregulates TUBB4B (Gene) and TUBB4B (Gene) is bound by Paclitaxel (Compound) and Paclitaxel may cause a moderate interaction that could exacerbate diseases when taken with Eribulin
Cyclosporine (Compound) downregulates PROS1 (Gene) and PROS1 (Gene) is downregulated by breast cancer (Disease) and breast cancer (Disease) is treated by Eribulin (Compound)
Cyclosporine (Compound) downregulates TUBB6 (Gene) and TUBB6 (Gene) is regulated by TUBB2A (Gene) and TUBB2A (Gene) is bound by Eribulin (Compound)
Cyclosporine (Compound) upregulates INPP1 (Gene) and INPP1 (Gene) is downregulated by breast cancer (Disease) and breast cancer (Disease) is treated by Eribulin (Compound)
Cyclosporine (Compound) downregulates PROS1 (Gene) and PROS1 (Gene) is upregulated by Daunorubicin (Compound) and Daunorubicin may cause a moderate interaction that could exacerbate diseases when taken with Eribulin
Cyclosporine (Compound) downregulates TUBB6 (Gene) and TUBB6 (Gene) regulates TUBB3 (Gene) and TUBB3 (Gene) is bound by Eribulin (Compound)
Cyclosporine (Compound) downregulates TUBB4B (Gene) and TUBB4B (Gene) is downregulated by Dasatinib (Compound) and Dasatinib may cause a moderate interaction that could exacerbate diseases when taken with Eribulin
Cyclosporine (Compound) upregulates INPP1 (Gene) and INPP1 (Gene) is upregulated by Bisacodyl (Compound) and Bisacodyl may cause a moderate interaction that could exacerbate diseases when taken with Eribulin
Cyclosporine (Compound) downregulates TUBB6 (Gene) and TUBB6 (Gene) is bound by Paclitaxel (Compound) and TUBB6 (Gene) is upregulated by Paclitaxel (Compound) and Paclitaxel may cause a moderate interaction that could exacerbate diseases when taken with Eribulin