DDInter790 DDInter1016
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of water from the body. Furosemide has a fast onset and short duration of action and has been used safely and effectively in both pediatric and adult patients. The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential. In addition to oral formulations, the solution for intravenous and intramuscular administration is also available, which is typically limited to patients who are unable to take oral medication or for patients in emergency clinical situations.
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose]. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. [sucrose]). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in patients with cirrhosis.[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.
Furosemide {u} (Compound) resembles {v} (Compound) Indapamide
Furosemide {u} (Compound) treats {v} (Disease) coronary artery disease
Furosemide {u} (Compound) binds {v} (Gene) SLC22A11
Furosemide {u} (Compound) palliates {v} (Disease) chronic kidney failure
Furosemide {u} (Compound) is included by {v} (Pharmacologic Class) Increased Diuresis at Loop of Henle
Furosemide {u} (Compound) causes {v} (Side Effect) Epigastric discomfort
Furosemide (Compound) resembles Indapamide (Compound)
Furosemide (Compound) treats coronary artery disease (Disease)
Furosemide (Compound) binds SLC22A11 (Gene)
Furosemide (Compound) palliates chronic kidney failure (Disease)
Furosemide (Compound) is included by Increased Diuresis at Loop of Henle (Pharmacologic Class)
Furosemide (Compound) causes Epigastric discomfort (Side Effect)