DDInter958 DDInter704
Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents.
Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and not on the mTORC2 protein.
Iodixanol {u} may lead to a major life threatening interaction when taken with {v} Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Everolimus
Iodixanol {u} (Compound) upregulates {v} (Gene) BAMBI
BAMBI {u} (Gene) is upregulated by {v} (Compound) Everolimus
Iodixanol {u} (Compound) downregulates {v} (Gene) HAT1
HAT1 {u} (Gene) is downregulated by {v} (Compound) Everolimus
Iodixanol {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Everolimus
Iodixanol {u} may lead to a major life threatening interaction when taken with {v} Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Pimecrolimus
Pimecrolimus {u} (Compound) resembles {v} (Compound) Everolimus
Iodixanol {u} (Compound) upregulates {v} (Gene) BAMBI
BAMBI {u} (Gene) is downregulated by {v} (Disease) kidney cancer
kidney cancer {u} (Disease) is treated by {v} (Compound) Everolimus
Iodixanol {u} (Compound) upregulates {v} (Gene) UBQLN2
UBQLN2 {u} (Gene) is upregulated by {v} (Compound) Sirolimus
Sirolimus {u} (Compound) resembles {v} (Compound) Everolimus
Iodixanol {u} (Compound) downregulates {v} (Gene) HAT1
HAT1 {u} (Gene) is downregulated by {v} (Compound) Temsirolimus
Temsirolimus {u} (Compound) resembles {v} (Compound) Everolimus
Iodixanol {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Pimecrolimus
Pimecrolimus {u} (Compound) resembles {v} (Compound) Everolimus
Iodixanol {u} (Compound) causes {v} (Side Effect) Cardiac failure
Cardiac failure {u} (Side Effect) is caused by {v} (Compound) Tacrolimus
Tacrolimus {u} (Compound) resembles {v} (Compound) Everolimus
Iodixanol may lead to a major life threatening interaction when taken with Sirolimus and Sirolimus (Compound) resembles Everolimus (Compound)
Iodixanol (Compound) upregulates BAMBI (Gene) and BAMBI (Gene) is upregulated by Everolimus (Compound)
Iodixanol (Compound) downregulates HAT1 (Gene) and HAT1 (Gene) is downregulated by Everolimus (Compound)
Iodixanol (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Everolimus (Compound)
Iodixanol may lead to a major life threatening interaction when taken with Sirolimus and Sirolimus (Compound) resembles Pimecrolimus (Compound) and Pimecrolimus (Compound) resembles Everolimus (Compound)
Iodixanol (Compound) upregulates BAMBI (Gene) and BAMBI (Gene) is downregulated by kidney cancer (Disease) and kidney cancer (Disease) is treated by Everolimus (Compound)
Iodixanol (Compound) upregulates UBQLN2 (Gene) and UBQLN2 (Gene) is upregulated by Sirolimus (Compound) and Sirolimus (Compound) resembles Everolimus (Compound)
Iodixanol (Compound) downregulates HAT1 (Gene) and HAT1 (Gene) is downregulated by Temsirolimus (Compound) and Temsirolimus (Compound) resembles Everolimus (Compound)
Iodixanol (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Pimecrolimus (Compound) and Pimecrolimus (Compound) resembles Everolimus (Compound)
Iodixanol (Compound) causes Cardiac failure (Side Effect) and Cardiac failure (Side Effect) is caused by Tacrolimus (Compound) and Tacrolimus (Compound) resembles Everolimus (Compound)