DDInter132 DDInter381
Atomoxetine is a selective norepinephrine (NE) reuptake inhibitor used for the treatment of attention deficit hyperactivity disorder (ADHD). Also known as the marketed product Strattera, atomoxetine is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve developmentally inappropriate symptoms associated with ADHD including distractibility, short attention span, hyperactivity, emotional lability, and impulsivity. Although the underlying pathophysiology that causes ADHD remains unclear, evidence suggests that dysregulation in noradrenergic and dopaminergic pathways plays a critical role in suboptimal executive functioning within prefrontal regions of the brain, which are involved in attention and memory. Atomoxetine has been shown to specifically increase NA and DA within the prefrontal cortex, but not in the nucleus accumbens (NA) or striatum. This is beneficial in the treatment of ADHD as DA activation in the subcortical NA and stri
Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe. It is used to treat hyperparathyroidism due to parathyroid tumours or renal failure.
Atomoxetine {u} (Compound) resembles {v} (Compound) Propranolol
Propranolol {u} (Compound) resembles {v} (Compound) Cinacalcet
Atomoxetine {u} (Compound) resembles {v} (Compound) Duloxetine
Duloxetine {u} (Compound) resembles {v} (Compound) Cinacalcet
Atomoxetine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dexfenfluramine
Dexfenfluramine {u} (Compound) resembles {v} (Compound) Cinacalcet
Atomoxetine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Cinacalcet
Atomoxetine {u} (Compound) causes {v} (Side Effect) Dyspepsia
Dyspepsia {u} (Side Effect) is caused by {v} (Compound) Cinacalcet
Atomoxetine {u} (Compound) resembles {v} (Compound) Propranolol
Propranolol {u} (Compound) resembles {v} (Compound) Duloxetine
Duloxetine {u} (Compound) resembles {v} (Compound) Cinacalcet
Atomoxetine {u} (Compound) resembles {v} (Compound) Duloxetine
Duloxetine {u} (Compound) resembles {v} (Compound) Propranolol
Propranolol {u} (Compound) resembles {v} (Compound) Cinacalcet
Atomoxetine {u} (Compound) resembles {v} (Compound) Demexiptiline
Demexiptiline {u} (Compound) resembles {v} (Compound) Propranolol
Propranolol {u} (Compound) resembles {v} (Compound) Cinacalcet
Atomoxetine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dexfenfluramine
Dexfenfluramine {u} may lead to a major life threatening interaction when taken with {v} Duloxetine
Duloxetine {u} (Compound) resembles {v} (Compound) Cinacalcet
Atomoxetine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Propranolol
Propranolol {u} (Compound) resembles {v} (Compound) Cinacalcet
Atomoxetine (Compound) resembles Propranolol (Compound) and Propranolol (Compound) resembles Cinacalcet (Compound)
Atomoxetine (Compound) resembles Duloxetine (Compound) and Duloxetine (Compound) resembles Cinacalcet (Compound)
Atomoxetine may cause a moderate interaction that could exacerbate diseases when taken with Dexfenfluramine and Dexfenfluramine (Compound) resembles Cinacalcet (Compound)
Atomoxetine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Cinacalcet (Compound)
Atomoxetine (Compound) causes Dyspepsia (Side Effect) and Dyspepsia (Side Effect) is caused by Cinacalcet (Compound)
Atomoxetine (Compound) resembles Propranolol (Compound) and Propranolol (Compound) resembles Duloxetine (Compound) and Duloxetine (Compound) resembles Cinacalcet (Compound)
Atomoxetine (Compound) resembles Duloxetine (Compound) and Duloxetine (Compound) resembles Propranolol (Compound) and Propranolol (Compound) resembles Cinacalcet (Compound)
Atomoxetine (Compound) resembles Demexiptiline (Compound) and Demexiptiline (Compound) resembles Propranolol (Compound) and Propranolol (Compound) resembles Cinacalcet (Compound)
Atomoxetine may cause a moderate interaction that could exacerbate diseases when taken with Dexfenfluramine and Dexfenfluramine may lead to a major life threatening interaction when taken with Duloxetine and Duloxetine (Compound) resembles Cinacalcet (Compound)
Atomoxetine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Propranolol (Compound) and Propranolol (Compound) resembles Cinacalcet (Compound)