DDInter551 DDInter105
Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the arachidonic acid pathway. Diflunisal is used to relieve pain accompanied with inflammation and in the symptomatic treatment of rheumatoid arthritis and osteoarthritis.
A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Diflunisal {u} (Compound) resembles {v} (Compound) Salsalate
Diflunisal {u} (Compound) resembles {v} (Compound) Salicylic acid
Diflunisal {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Olsalazine
Diflunisal {u} (Compound) binds {v} (Gene) PTGS2
Diflunisal {u} (Compound) upregulates {v} (Gene) HLA-DMA
Diflunisal {u} (Compound) palliates {v} (Disease) rheumatoid arthritis
Diflunisal {u} (Compound) is included by {v} (Pharmacologic Class) Nonsteroidal Anti-inflammatory Compounds
Diflunisal {u} (Compound) downregulates {v} (Gene) EPN2
Diflunisal {u} (Compound) causes {v} (Side Effect) Photosensitivity reaction
Diflunisal {u} may cause a minor interaction that can limit clinical effects when taken with {v} Hyaluronidase
Diflunisal (Compound) resembles Salsalate (Compound)
Diflunisal (Compound) resembles Salicylic acid (Compound)
Diflunisal may cause a moderate interaction that could exacerbate diseases when taken with Olsalazine
Diflunisal (Compound) binds PTGS2 (Gene)
Diflunisal (Compound) upregulates HLA-DMA (Gene)
Diflunisal (Compound) palliates rheumatoid arthritis (Disease)
Diflunisal (Compound) is included by Nonsteroidal Anti-inflammatory Compounds (Pharmacologic Class)
Diflunisal (Compound) downregulates EPN2 (Gene)
Diflunisal (Compound) causes Photosensitivity reaction (Side Effect)
Diflunisal may cause a minor interaction that can limit clinical effects when taken with Hyaluronidase