DDInter1135 DDInter856
A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated heparin is more specific than LMWH for thrombin. Furthermore, the effects of UH can typically be reversed by using protamine sulfate.
Meclofenamic acid {u} (Compound) resembles {v} (Compound) Salicylic acid
Meclofenamic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acetylsalicylic acid
Meclofenamic acid {u} (Compound) binds {v} (Gene) ALOX5
Meclofenamic acid {u} (Compound) upregulates {v} (Gene) DMTF1
Meclofenamic acid {u} (Compound) downregulates {v} (Gene) CSRP1
Meclofenamic acid {u} (Compound) causes {v} (Side Effect) Abdominal pain
Meclofenamic acid {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ranitidine
Meclofenamic acid {u} may cause a minor interaction that can limit clinical effects when taken with {v} Linaclotide
Meclofenamic acid {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Prednisone
Meclofenamic acid {u} may lead to a major life threatening interaction when taken with {v} Ibritumomab tiuxetan
Meclofenamic acid (Compound) resembles Salicylic acid (Compound)
Meclofenamic acid may cause a moderate interaction that could exacerbate diseases when taken with Acetylsalicylic acid
Meclofenamic acid (Compound) binds ALOX5 (Gene)
Meclofenamic acid (Compound) upregulates DMTF1 (Gene)
Meclofenamic acid (Compound) downregulates CSRP1 (Gene)
Meclofenamic acid (Compound) causes Abdominal pain (Side Effect)
Meclofenamic acid may cause a minor interaction that can limit clinical effects when taken with Ranitidine
Meclofenamic acid may cause a minor interaction that can limit clinical effects when taken with Linaclotide
Meclofenamic acid may cause a moderate interaction that could exacerbate diseases when taken with Prednisone
Meclofenamic acid may lead to a major life threatening interaction when taken with Ibritumomab tiuxetan