DDInter293 DDInter178
Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965. Aside from the above uses, this drug is also given to control the symptoms of bipolar 1. Interestingly, carbamazepine was the first anticonvulsant used to treat individuals with bipolar disorder.
Bendamustine is a nitrogen mustard drug indicated for use in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed during or within six months of treatment with rituximab or a rituximab-containing regimen. Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases resulting in cell death. It is active against both active and quiescent cells, although the exact mechanism of action is unknown.
Carbamazepine {u} (Compound) resembles {v} (Compound) Magnesium salicylate
Carbamazepine {u} (Compound) resembles {v} (Compound) Modafinil
Carbamazepine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methdilazine
Carbamazepine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cyproheptadine
Carbamazepine {u} (Compound) treats {v} (Disease) epilepsy syndrome
Carbamazepine {u} (Compound) binds {v} (Gene) SCN9A
Carbamazepine {u} (Compound) upregulates {v} (Gene) PLCB3
Carbamazepine {u} (Compound) palliates {v} (Disease) bipolar disorder
Carbamazepine {u} (Compound) is included by {v} (Pharmacologic Class) Cytochrome P450 1A2 Inducers
Carbamazepine {u} (Compound) downregulates {v} (Gene) TIMM9
Carbamazepine (Compound) resembles Magnesium salicylate (Compound)
Carbamazepine (Compound) resembles Modafinil (Compound)
Carbamazepine may cause a moderate interaction that could exacerbate diseases when taken with Methdilazine
Carbamazepine may cause a moderate interaction that could exacerbate diseases when taken with Cyproheptadine
Carbamazepine (Compound) treats epilepsy syndrome (Disease)
Carbamazepine (Compound) binds SCN9A (Gene)
Carbamazepine (Compound) upregulates PLCB3 (Gene)
Carbamazepine (Compound) palliates bipolar disorder (Disease)
Carbamazepine (Compound) is included by Cytochrome P450 1A2 Inducers (Pharmacologic Class)
Carbamazepine (Compound) downregulates TIMM9 (Gene)