DDInter1606 DDInter927
Adrenergic beta-agonist used to control premature labor.
Inotuzumab ozogamicin is an antibody-drug conjugate using linker and cytotoxic drug technology similar to that developed for the ground-breaking treatment Mylotarg (), which was approved by the US FDA in 2000 for the treatment of acute myeloid leukaemia. Inotuzumab ozogamicin consists of a recombinant humanised IgG4 kappa CD22-targeting monoclonal antibody covalently attached to calicheamicin derivative, N-acetyl-gamma-calicheamicin dimethylhydrazide, which is a potent DNA-binding cytotoxic agent . Developed by Pfizer and UCB, inotuzumab ozogamicin was granted approval by EU in June 2017 followed by FDA on August 17th, 2017 for the treatment of adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL). ALL is a rapidly progressing cancer of the bone marrow that is associated with high mortality rates and low therapeutic response from standard chemotherapies in relasping conditions. In a randomized trial, inotuzumab ozogamicin displayed higher percentages of patients undergoing longer periods of complete remission with no evidence of disease in comparison to patients receiving alternative chemotherapy .
Ritodrine {u} (Compound) resembles {v} (Compound) Arformoterol
Ritodrine {u} (Compound) resembles {v} (Compound) Dobutamine
Ritodrine {u} (Compound) binds {v} (Gene) GALR3
Ritodrine {u} (Compound) upregulates {v} (Gene) TGFBR2
Ritodrine {u} (Compound) downregulates {v} (Gene) POLR2I
Ritodrine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Flunisolide
Ritodrine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ciclesonide
Ritodrine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Isoprenaline
Ritodrine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Phenylpropanolamine
Ritodrine {u} may lead to a major life threatening interaction when taken with {v} Ivosidenib
Ritodrine (Compound) resembles Arformoterol (Compound)
Ritodrine (Compound) resembles Dobutamine (Compound)
Ritodrine (Compound) binds GALR3 (Gene)
Ritodrine (Compound) upregulates TGFBR2 (Gene)
Ritodrine (Compound) downregulates POLR2I (Gene)
Ritodrine may cause a minor interaction that can limit clinical effects when taken with Flunisolide
Ritodrine may cause a minor interaction that can limit clinical effects when taken with Ciclesonide
Ritodrine may cause a moderate interaction that could exacerbate diseases when taken with Isoprenaline
Ritodrine may cause a moderate interaction that could exacerbate diseases when taken with Phenylpropanolamine
Ritodrine may lead to a major life threatening interaction when taken with Ivosidenib