DDInter1326 DDInter1180
Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resembles [clozapine] and only differs by two additional methyl groups and the absence of a chloride moiety. It was discovered by scientists at Eli Lilly and approved to be marketed in the US in 1996.
Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Olanzapine {u} (Compound) resembles {v} (Compound) Clozapine
Olanzapine {u} (Compound) resembles {v} (Compound) Pirenzepine
Olanzapine {u} (Compound) binds {v} (Gene) HTR7
Olanzapine {u} (Compound) upregulates {v} (Gene) NNT
Olanzapine {u} (Compound) palliates {v} (Disease) Gilles de la Tourette syndrome
Olanzapine {u} (Compound) downregulates {v} (Gene) ITGAE
Olanzapine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metronidazole
Olanzapine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cetirizine
Olanzapine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Acarbose
Olanzapine {u} may lead to a major life threatening interaction when taken with {v} Potassium chloride
Olanzapine (Compound) resembles Clozapine (Compound)
Olanzapine (Compound) resembles Pirenzepine (Compound)
Olanzapine (Compound) binds HTR7 (Gene)
Olanzapine (Compound) upregulates NNT (Gene)
Olanzapine (Compound) palliates Gilles de la Tourette syndrome (Disease)
Olanzapine (Compound) downregulates ITGAE (Gene)
Olanzapine may cause a minor interaction that can limit clinical effects when taken with Metronidazole
Olanzapine may cause a moderate interaction that could exacerbate diseases when taken with Cetirizine
Olanzapine may cause a moderate interaction that could exacerbate diseases when taken with Acarbose
Olanzapine may lead to a major life threatening interaction when taken with Potassium chloride