DDInter1382 DDInter556
Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first dose of a course of chemotherapy and is the only drug of its class approved for this use by the U.S. Food and Drug Administration. As of 2008, it is the most recent 5-HT3 antagonist to enter clinical use.
Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough. It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more effective antitussive agent to help reduce the spread of airborne infectious diseases such as tuburculosis. It was marketed in 1911.
Palonosetron {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Galantamine
Galantamine {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Palonosetron {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxymorphone
Oxymorphone {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Palonosetron {u} may lead to a major life threatening interaction when taken with {v} Dextromethorphan
Dextromethorphan {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Palonosetron {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Morphine
Morphine {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Palonosetron {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Hydromorphone
Hydromorphone {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Palonosetron {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Dihydrocodeine
Palonosetron {u} (Compound) causes {v} (Side Effect) Somnolence
Somnolence {u} (Side Effect) is caused by {v} (Compound) Dihydrocodeine
Palonosetron {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Galantamine
Galantamine {u} (Compound) resembles {v} (Compound) Hydrocodone
Hydrocodone {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Palonosetron {u} may lead to a major life threatening interaction when taken with {v} Dextromethorphan
Dextromethorphan {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxymorphone
Oxymorphone {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Palonosetron {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Morphine
Morphine {u} (Compound) resembles {v} (Compound) Galantamine
Galantamine {u} (Compound) resembles {v} (Compound) Dihydrocodeine
Palonosetron may cause a moderate interaction that could exacerbate diseases when taken with Galantamine and Galantamine (Compound) resembles Dihydrocodeine (Compound)
Palonosetron may cause a moderate interaction that could exacerbate diseases when taken with Oxymorphone and Oxymorphone (Compound) resembles Dihydrocodeine (Compound)
Palonosetron may lead to a major life threatening interaction when taken with Dextromethorphan and Dextromethorphan (Compound) resembles Dihydrocodeine (Compound)
Palonosetron may cause a moderate interaction that could exacerbate diseases when taken with Morphine and Morphine (Compound) resembles Dihydrocodeine (Compound)
Palonosetron may cause a moderate interaction that could exacerbate diseases when taken with Hydromorphone and Hydromorphone (Compound) resembles Dihydrocodeine (Compound)
Palonosetron (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Dihydrocodeine (Compound)
Palonosetron (Compound) causes Somnolence (Side Effect) and Somnolence (Side Effect) is caused by Dihydrocodeine (Compound)
Palonosetron may cause a moderate interaction that could exacerbate diseases when taken with Galantamine and Galantamine (Compound) resembles Hydrocodone (Compound) and Hydrocodone (Compound) resembles Dihydrocodeine (Compound)
Palonosetron may lead to a major life threatening interaction when taken with Dextromethorphan and Dextromethorphan may cause a moderate interaction that could exacerbate diseases when taken with Oxymorphone and Oxymorphone (Compound) resembles Dihydrocodeine (Compound)
Palonosetron may cause a moderate interaction that could exacerbate diseases when taken with Morphine and Morphine (Compound) resembles Galantamine (Compound) and Galantamine (Compound) resembles Dihydrocodeine (Compound)