DDInter948 DDInter625
Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Elagolix has been used in trials studying the basic science and treatment of Endometriosis, Folliculogenesis, Uterine Fibroids, Heavy Uterine Bleeding, and Heavy Menstrual Bleeding. As of 24 July 2018, however, the U.S. Food and Drug Administration (FDA) approved AbbVie's elagolix under the brand name Orilissa as the first and only oral gonadotropin-releasing hormone (GnRH) antagonist specifically developed for women with moderate to severe endometriosis pain . It has been determined that endometriosis is one of the most common gynecologic disorders in the United States [A35868, A35869, F801]. In particular, estimates suggest that one in ten women of reproductive age is affected by endometriosis and experience debilitating pain symptoms [A35868, A35869, F801]. Moreover, women who are affected by this condition can suffer for up to six to ten years and visit multiple physicians before receiving a proper diagnosis [A35868, A35869, F801]. Subsequently, as Orilissa (elagolix) was approved by the FDA under priority review , this expedited new approval gives healthcare professionals another valuable option for treating the potentially unmet needs of women who are affected by endometriosis, depending on their specific type and severity of endometriosis pain.
Elagolix {u} may cause a minor interaction that can limit clinical effects when taken with {v} Bortezomib
Elagolix {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Osilodrostat
Elagolix {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Macimorelin
Elagolix {u} may lead to a major life threatening interaction when taken with {v} Rifampicin
Elagolix {u} may lead to a major life threatening interaction when taken with {v} Tazemetostat
Elagolix may cause a minor interaction that can limit clinical effects when taken with Bortezomib
Elagolix may cause a moderate interaction that could exacerbate diseases when taken with Osilodrostat
Elagolix may cause a moderate interaction that could exacerbate diseases when taken with Macimorelin
Elagolix may lead to a major life threatening interaction when taken with Rifampicin
Elagolix may lead to a major life threatening interaction when taken with Tazemetostat