DDInter747 DDInter1371
Fludrocortisone is a synthetic mineralocorticoid used in conjunction with [hydrocortisone] to replace missing endogenous corticosteroids in patients with adrenal insufficiency.[A187169,A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and is structurally analogous to [cortisol], differing only by a fluorine atom at the 9-position of the steroid structure - this fluorination is thought to be crucial to fludrocortisone's significant mineralocorticoid potency.
Oxymetholone is a synthetic anabolic steroid marketed under the brand name Anapolon by Hoffmann La Roche Limitedand used in the treatment of osteoporosis, anaemia, and as an agent to stimulate muscle growth in malnourished or underdeveloped patients. Anabolic-androgenic steroids (AAS), such as oxymetholone, have been abused by bodybuilders and athletes. The uncontrolled misuse of oxymetholone can lead to a large variety of detrimental effects, the most often reported of which are cardiovascular events. In 2009, no producers of oxymetholone were identified worldwide (SRI 2009), but it was available from 14 suppliers, including 8 U.S. suppliers (ChemSources 2009).
Fludrocortisone {u} (Compound) resembles {v} (Compound) Dexamethasone
Fludrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Testosterone
Fludrocortisone {u} (Compound) binds {v} (Gene) NR3C1
Fludrocortisone {u} (Compound) palliates {v} (Disease) Parkinson's disease
Fludrocortisone {u} (Compound) causes {v} (Side Effect) Hyperglycaemia
Fludrocortisone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Aluminum hydroxide
Fludrocortisone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ticlopidine
Fludrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Bisacodyl
Fludrocortisone {u} may lead to a major life threatening interaction when taken with {v} Certolizumab pegol
Fludrocortisone {u} may lead to a major life threatening interaction when taken with {v} Moxifloxacin
Fludrocortisone (Compound) resembles Dexamethasone (Compound)
Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Testosterone
Fludrocortisone (Compound) binds NR3C1 (Gene)
Fludrocortisone (Compound) palliates Parkinson's disease (Disease)
Fludrocortisone (Compound) causes Hyperglycaemia (Side Effect)
Fludrocortisone may cause a minor interaction that can limit clinical effects when taken with Aluminum hydroxide
Fludrocortisone may cause a minor interaction that can limit clinical effects when taken with Ticlopidine
Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Bisacodyl
Fludrocortisone may lead to a major life threatening interaction when taken with Certolizumab pegol
Fludrocortisone may lead to a major life threatening interaction when taken with Moxifloxacin