DDInter258 DDInter593
A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Doxepin is a psychotropic agent with antidepressant and anxiolytic properties. It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to [cidoxepin]. Doxepin commonly produces a 5:1 (E):(Z) racemic mixture. In a strict sense, doxepin is not a tricyclic antidepressant but it is commonly associated with the class since it shares a lot of properties with members of the drug family including [amitriptyline], [clomipramine], [desipramine], [imipramine], [nortriptyline], [protriptyline] and [trimipramine]. Doxepin was developed by Pfizer and FDA approved in 1969 as an antidepressant. However, in 2010 it was approved for the treatment of insomnia. The latter indication was presented by Pernix Therapeutics.
Butorphanol {u} (Compound) causes {v} (Side Effect) Sinusitis
Sinusitis {u} (Side Effect) is caused by {v} (Compound) Doxepin
Butorphanol {u} (Compound) resembles {v} (Compound) Nalbuphine
Nalbuphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Doxepin
Butorphanol {u} (Compound) resembles {v} (Compound) Pentazocine
Pentazocine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Doxepin
Butorphanol {u} (Compound) resembles {v} (Compound) Dezocine
Dezocine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Doxepin
Butorphanol {u} (Compound) causes {v} (Side Effect) Sinusitis
Sinusitis {u} (Side Effect) is caused by {v} (Compound) Oxcarbazepine
Oxcarbazepine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Doxepin
Butorphanol {u} (Compound) causes {v} (Side Effect) Constipation
Constipation {u} (Side Effect) is caused by {v} (Compound) Thiothixene
Thiothixene {u} (Compound) resembles {v} (Compound) Doxepin
Butorphanol {u} (Compound) causes {v} (Side Effect) Drug withdrawal syndrome
Drug withdrawal syndrome {u} (Side Effect) is caused by {v} (Compound) Imipramine
Imipramine {u} (Compound) resembles {v} (Compound) Doxepin
Butorphanol {u} (Compound) causes {v} (Side Effect) Deafness
Deafness {u} (Side Effect) is caused by {v} (Compound) Estradiol
Estradiol {u} may cause a minor interaction that can limit clinical effects when taken with {v} Doxepin
Butorphanol {u} (Compound) causes {v} (Side Effect) Ageusia
Ageusia {u} (Side Effect) is caused by {v} (Compound) Cyclobenzaprine
Cyclobenzaprine {u} may lead to a major life threatening interaction when taken with {v} Doxepin
Butorphanol {u} (Compound) resembles {v} (Compound) Nalbuphine
Nalbuphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Promethazine
Promethazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Doxepin
Butorphanol (Compound) causes Sinusitis (Side Effect) and Sinusitis (Side Effect) is caused by Doxepin (Compound)
Butorphanol (Compound) resembles Nalbuphine (Compound) and Nalbuphine may cause a moderate interaction that could exacerbate diseases when taken with Doxepin
Butorphanol (Compound) resembles Pentazocine (Compound) and Pentazocine may cause a moderate interaction that could exacerbate diseases when taken with Doxepin
Butorphanol (Compound) resembles Dezocine (Compound) and Dezocine may cause a moderate interaction that could exacerbate diseases when taken with Doxepin
Butorphanol (Compound) causes Sinusitis (Side Effect) and Sinusitis (Side Effect) is caused by Oxcarbazepine (Compound) and Oxcarbazepine may cause a moderate interaction that could exacerbate diseases when taken with Doxepin
Butorphanol (Compound) causes Constipation (Side Effect) and Constipation (Side Effect) is caused by Thiothixene (Compound) and Thiothixene (Compound) resembles Doxepin (Compound)
Butorphanol (Compound) causes Drug withdrawal syndrome (Side Effect) and Drug withdrawal syndrome (Side Effect) is caused by Imipramine (Compound) and Imipramine (Compound) resembles Doxepin (Compound)
Butorphanol (Compound) causes Deafness (Side Effect) and Deafness (Side Effect) is caused by Estradiol (Compound) and Estradiol may cause a minor interaction that can limit clinical effects when taken with Doxepin
Butorphanol (Compound) causes Ageusia (Side Effect) and Ageusia (Side Effect) is caused by Cyclobenzaprine (Compound) and Cyclobenzaprine may lead to a major life threatening interaction when taken with Doxepin
Butorphanol (Compound) resembles Nalbuphine (Compound) and Nalbuphine may cause a moderate interaction that could exacerbate diseases when taken with Promethazine and Promethazine may cause a moderate interaction that could exacerbate diseases when taken with Doxepin