DDInter1374 DDInter1123
A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.
Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain and cerebrospinal fluid, into interstitial fluid and plasma. As a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure may be reduced. Mannitol may also be used for the promotion of diuresis before irreversible renal failure becomes established; the promotion of urinary excretion of toxic substances; as an Antiglaucoma agent; and as a renal function diagnostic aid. On October 30, 2020, mannitol was approved by the FDA as add-on maintenance therapy for the control of pulmonary symptoms associated with cystic fibrosis in adult patients and is currently marketed for this indication under the name BRONCHITOL® by Chiesi USA Inc.
Oxytetracycline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Acetazolamide
Acetazolamide {u} (Compound) treats {v} (Disease) glaucoma
glaucoma {u} (Disease) is palliated by {v} (Compound) Mannitol
Oxytetracycline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Etacrynic acid
Etacrynic acid {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Mannitol
Oxytetracycline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Torasemide
Torasemide {u} (Compound) causes {v} (Side Effect) Oropharyngeal discomfort
Oropharyngeal discomfort {u} (Side Effect) is caused by {v} (Compound) Mannitol
Oxytetracycline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Amiloride
Amiloride {u} (Compound) is included by {v} (Pharmacologic Class) Increased Diuresis
Increased Diuresis {u} (Pharmacologic Class) includes {v} (Compound) Mannitol
Oxytetracycline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Chlorothiazide
Chlorothiazide {u} (Compound) is included by {v} (Pharmacologic Class) Increased Diuresis
Increased Diuresis {u} (Pharmacologic Class) includes {v} (Compound) Mannitol
Oxytetracycline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Spironolactone
Spironolactone {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Mannitol
Oxytetracycline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methotrexate
Methotrexate {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Mannitol
Oxytetracycline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Methysergide
Methysergide {u} (Compound) causes {v} (Side Effect) Discomfort
Discomfort {u} (Side Effect) is caused by {v} (Compound) Mannitol
Oxytetracycline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Oxacillin
Oxacillin {u} (Compound) causes {v} (Side Effect) Vomiting
Vomiting {u} (Side Effect) is caused by {v} (Compound) Mannitol
Oxytetracycline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Mycophenolate mofetil
Mycophenolate mofetil {u} (Compound) binds {v} (Gene) ABCB1
ABCB1 {u} (Gene) is bound by {v} (Compound) Mannitol
Oxytetracycline may cause a minor interaction that can limit clinical effects when taken with Acetazolamide and Acetazolamide (Compound) treats glaucoma (Disease) and glaucoma (Disease) is palliated by Mannitol (Compound)
Oxytetracycline may cause a minor interaction that can limit clinical effects when taken with Etacrynic acid and Etacrynic acid (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Mannitol (Compound)
Oxytetracycline may cause a minor interaction that can limit clinical effects when taken with Torasemide and Torasemide (Compound) causes Oropharyngeal discomfort (Side Effect) and Oropharyngeal discomfort (Side Effect) is caused by Mannitol (Compound)
Oxytetracycline may cause a minor interaction that can limit clinical effects when taken with Amiloride and Amiloride (Compound) is included by Increased Diuresis (Pharmacologic Class) and Increased Diuresis (Pharmacologic Class) includes Mannitol (Compound)
Oxytetracycline may cause a minor interaction that can limit clinical effects when taken with Chlorothiazide and Chlorothiazide (Compound) is included by Increased Diuresis (Pharmacologic Class) and Increased Diuresis (Pharmacologic Class) includes Mannitol (Compound)
Oxytetracycline may cause a minor interaction that can limit clinical effects when taken with Spironolactone and Spironolactone (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Mannitol (Compound)
Oxytetracycline may cause a moderate interaction that could exacerbate diseases when taken with Methotrexate and Methotrexate (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Mannitol (Compound)
Oxytetracycline may cause a moderate interaction that could exacerbate diseases when taken with Methysergide and Methysergide (Compound) causes Discomfort (Side Effect) and Discomfort (Side Effect) is caused by Mannitol (Compound)
Oxytetracycline may cause a moderate interaction that could exacerbate diseases when taken with Oxacillin and Oxacillin (Compound) causes Vomiting (Side Effect) and Vomiting (Side Effect) is caused by Mannitol (Compound)
Oxytetracycline may cause a moderate interaction that could exacerbate diseases when taken with Mycophenolate mofetil and Mycophenolate mofetil (Compound) binds ABCB1 (Gene) and ABCB1 (Gene) is bound by Mannitol (Compound)