DDInter1158 DDInter1009
An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease. Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical agent. Throughout the late seventies and the eighties, important research initiatives developed stable mesalazine formulations like the eudragit-S coating of Asacol brand mesalazine and the Pentasa brand's encapsulation of mesalazine within microgranules. In the present day, contemporary research regarding novel methods to stabilize mesalazine continues and interest in the agent's capacity to decrease inflammatory activity and subsequently potentially reduce the risk of colorectal cancer in conditions like ulcerative colitis is maintained.[A174019,A174022]
Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Mesalazine {u} (Compound) binds {v} (Gene) PTGS1
PTGS1 {u} (Gene) is bound by {v} (Compound) Ketoprofen
Mesalazine {u} (Compound) causes {v} (Side Effect) Migraine
Migraine {u} (Side Effect) is caused by {v} (Compound) Ketoprofen
Mesalazine {u} (Compound) resembles {v} (Compound) Olsalazine
Olsalazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ketoprofen
Mesalazine {u} (Compound) binds {v} (Gene) PTGS1
PTGS1 {u} (Gene) is bound by {v} (Compound) Mefenamic acid
Mefenamic acid {u} (Compound) resembles {v} (Compound) Ketoprofen
Mesalazine {u} (Compound) causes {v} (Side Effect) Migraine
Migraine {u} (Side Effect) is caused by {v} (Compound) Flurbiprofen
Flurbiprofen {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ketoprofen
Mesalazine {u} (Compound) causes {v} (Side Effect) Stomatitis
Stomatitis {u} (Side Effect) is caused by {v} (Compound) Mefenamic acid
Mefenamic acid {u} (Compound) resembles {v} (Compound) Ketoprofen
Mesalazine {u} (Compound) causes {v} (Side Effect) Hypersensitivity
Hypersensitivity {u} (Side Effect) is caused by {v} (Compound) Tropicamide
Tropicamide {u} (Compound) resembles {v} (Compound) Ketoprofen
Mesalazine {u} (Compound) resembles {v} (Compound) Olsalazine
Olsalazine {u} (Compound) resembles {v} (Compound) Salsalate
Salsalate {u} (Compound) resembles {v} (Compound) Ketoprofen
Mesalazine {u} (Compound) causes {v} (Side Effect) Glossodynia
Glossodynia {u} (Side Effect) is caused by {v} (Compound) Famotidine
Famotidine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ketoprofen
Mesalazine {u} (Compound) resembles {v} (Compound) Olsalazine
Olsalazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Flurbiprofen
Flurbiprofen {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Ketoprofen
Mesalazine (Compound) binds PTGS1 (Gene) and PTGS1 (Gene) is bound by Ketoprofen (Compound)
Mesalazine (Compound) causes Migraine (Side Effect) and Migraine (Side Effect) is caused by Ketoprofen (Compound)
Mesalazine (Compound) resembles Olsalazine (Compound) and Olsalazine may cause a moderate interaction that could exacerbate diseases when taken with Ketoprofen
Mesalazine (Compound) binds PTGS1 (Gene) and PTGS1 (Gene) is bound by Mefenamic acid (Compound) and Mefenamic acid (Compound) resembles Ketoprofen (Compound)
Mesalazine (Compound) causes Migraine (Side Effect) and Migraine (Side Effect) is caused by Flurbiprofen (Compound) and Flurbiprofen may cause a moderate interaction that could exacerbate diseases when taken with Ketoprofen
Mesalazine (Compound) causes Stomatitis (Side Effect) and Stomatitis (Side Effect) is caused by Mefenamic acid (Compound) and Mefenamic acid (Compound) resembles Ketoprofen (Compound)
Mesalazine (Compound) causes Hypersensitivity (Side Effect) and Hypersensitivity (Side Effect) is caused by Tropicamide (Compound) and Tropicamide (Compound) resembles Ketoprofen (Compound)
Mesalazine (Compound) resembles Olsalazine (Compound) and Olsalazine (Compound) resembles Salsalate (Compound) and Salsalate (Compound) resembles Ketoprofen (Compound)
Mesalazine (Compound) causes Glossodynia (Side Effect) and Glossodynia (Side Effect) is caused by Famotidine (Compound) and Famotidine may cause a minor interaction that can limit clinical effects when taken with Ketoprofen
Mesalazine (Compound) resembles Olsalazine (Compound) and Olsalazine may cause a moderate interaction that could exacerbate diseases when taken with Flurbiprofen and Flurbiprofen may cause a moderate interaction that could exacerbate diseases when taken with Ketoprofen