DDInter1535 DDInter1544
A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking.
Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties. The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies. Prucalopride was developed by Shire Development LLC and approved for use in Europe in 2009, in Canada on December 7, 2011 and by the FDA on December 17, 2018.
Propantheline {u} (Compound) resembles {v} (Compound) Isopropamide
Propantheline {u} (Compound) resembles {v} (Compound) Methantheline
Propantheline {u} (Compound) treats {v} (Disease) pancreatitis
Propantheline {u} (Compound) binds {v} (Gene) CHRM1
Propantheline {u} (Compound) downregulates {v} (Gene) GJA1
Propantheline {u} (Compound) causes {v} (Side Effect) Constipation
Propantheline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Chlorothiazide
Propantheline {u} may cause a minor interaction that can limit clinical effects when taken with {v} Acetaminophen
Propantheline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tapentadol
Propantheline {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Sotalol
Propantheline (Compound) resembles Isopropamide (Compound)
Propantheline (Compound) resembles Methantheline (Compound)
Propantheline (Compound) treats pancreatitis (Disease)
Propantheline (Compound) binds CHRM1 (Gene)
Propantheline (Compound) downregulates GJA1 (Gene)
Propantheline (Compound) causes Constipation (Side Effect)
Propantheline may cause a minor interaction that can limit clinical effects when taken with Chlorothiazide
Propantheline may cause a minor interaction that can limit clinical effects when taken with Acetaminophen
Propantheline may cause a moderate interaction that could exacerbate diseases when taken with Tapentadol
Propantheline may cause a moderate interaction that could exacerbate diseases when taken with Sotalol