DDInter1832 DDInter1544
Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties. The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies. Prucalopride was developed by Shire Development LLC and approved for use in Europe in 2009, in Canada on December 7, 2011 and by the FDA on December 17, 2018.
Tolterodine {u} (Compound) resembles {v} (Compound) Orphenadrine
Tolterodine {u} (Compound) resembles {v} (Compound) Pheniramine
Tolterodine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Dexbrompheniramine
Tolterodine {u} (Compound) binds {v} (Gene) CYP2C19
Tolterodine {u} (Compound) palliates {v} (Disease) multiple sclerosis
Tolterodine {u} (Compound) is included by {v} (Pharmacologic Class) Cholinergic Muscarinic Antagonists
Tolterodine {u} (Compound) causes {v} (Side Effect) Dry mouth
Tolterodine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Rolapitant
Tolterodine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Fenfluramine
Tolterodine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Fedratinib
Tolterodine (Compound) resembles Orphenadrine (Compound)
Tolterodine (Compound) resembles Pheniramine (Compound)
Tolterodine may cause a moderate interaction that could exacerbate diseases when taken with Dexbrompheniramine
Tolterodine (Compound) binds CYP2C19 (Gene)
Tolterodine (Compound) palliates multiple sclerosis (Disease)
Tolterodine (Compound) is included by Cholinergic Muscarinic Antagonists (Pharmacologic Class)
Tolterodine (Compound) causes Dry mouth (Side Effect)
Tolterodine may cause a minor interaction that can limit clinical effects when taken with Rolapitant
Tolterodine may cause a minor interaction that can limit clinical effects when taken with Fenfluramine
Tolterodine may cause a moderate interaction that could exacerbate diseases when taken with Fedratinib