DDInter747 DDInter396
Fludrocortisone is a synthetic mineralocorticoid used in conjunction with [hydrocortisone] to replace missing endogenous corticosteroids in patients with adrenal insufficiency.[A187169,A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and is structurally analogous to [cortisol], differing only by a fluorine atom at the 9-position of the steroid structure - this fluorination is thought to be crucial to fludrocortisone's significant mineralocorticoid potency.
Clevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.
Fludrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nicardipine
Nicardipine {u} (Compound) resembles {v} (Compound) Clevidipine
Fludrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nifedipine
Nifedipine {u} (Compound) resembles {v} (Compound) Clevidipine
Fludrocortisone {u} (Compound) causes {v} (Side Effect) Headache
Headache {u} (Side Effect) is caused by {v} (Compound) Clevidipine
Fludrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nicardipine
Nicardipine {u} (Compound) resembles {v} (Compound) Nitrendipine
Nitrendipine {u} (Compound) resembles {v} (Compound) Clevidipine
Fludrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nifedipine
Nifedipine {u} (Compound) resembles {v} (Compound) Nitrendipine
Nitrendipine {u} (Compound) resembles {v} (Compound) Clevidipine
Fludrocortisone {u} (Compound) causes {v} (Side Effect) Headache
Headache {u} (Side Effect) is caused by {v} (Compound) Nicardipine
Nicardipine {u} (Compound) resembles {v} (Compound) Clevidipine
Fludrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nicardipine
Nicardipine {u} (Compound) resembles {v} (Compound) Nifedipine
Nifedipine {u} (Compound) resembles {v} (Compound) Clevidipine
Fludrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nifedipine
Nifedipine {u} (Compound) resembles {v} (Compound) Nimodipine
Nimodipine {u} (Compound) resembles {v} (Compound) Clevidipine
Fludrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nicardipine
Nicardipine {u} (Compound) binds {v} (Gene) CYP2D6
CYP2D6 {u} (Gene) is bound by {v} (Compound) Clevidipine
Fludrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nifedipine
Nifedipine {u} (Compound) binds {v} (Gene) CYP1A2
CYP1A2 {u} (Gene) is bound by {v} (Compound) Clevidipine
Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Nicardipine and Nicardipine (Compound) resembles Clevidipine (Compound)
Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Nifedipine and Nifedipine (Compound) resembles Clevidipine (Compound)
Fludrocortisone (Compound) causes Headache (Side Effect) and Headache (Side Effect) is caused by Clevidipine (Compound)
Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Nicardipine and Nicardipine (Compound) resembles Nitrendipine (Compound) and Nitrendipine (Compound) resembles Clevidipine (Compound)
Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Nifedipine and Nifedipine (Compound) resembles Nitrendipine (Compound) and Nitrendipine (Compound) resembles Clevidipine (Compound)
Fludrocortisone (Compound) causes Headache (Side Effect) and Headache (Side Effect) is caused by Nicardipine (Compound) and Nicardipine (Compound) resembles Clevidipine (Compound)
Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Nicardipine and Nicardipine (Compound) resembles Nifedipine (Compound) and Nifedipine (Compound) resembles Clevidipine (Compound)
Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Nifedipine and Nifedipine (Compound) resembles Nimodipine (Compound) and Nimodipine (Compound) resembles Clevidipine (Compound)
Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Nicardipine and Nicardipine (Compound) binds CYP2D6 (Gene) and CYP2D6 (Gene) is bound by Clevidipine (Compound)
Fludrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Nifedipine and Nifedipine (Compound) binds CYP1A2 (Gene) and CYP1A2 (Gene) is bound by Clevidipine (Compound)