DDInter576 DDInter1757
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.
Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects.
Disulfiram {u} (Compound) causes {v} (Side Effect) Neuropathy peripheral
Neuropathy peripheral {u} (Side Effect) is caused by {v} (Compound) Telbivudine
Disulfiram {u} (Compound) causes {v} (Side Effect) Neuropathy peripheral
Neuropathy peripheral {u} (Side Effect) is caused by {v} (Compound) Zidovudine
Zidovudine {u} (Compound) resembles {v} (Compound) Telbivudine
Disulfiram {u} (Compound) causes {v} (Side Effect) Abdominal discomfort
Abdominal discomfort {u} (Side Effect) is caused by {v} (Compound) Orlistat
Orlistat {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Telbivudine
Disulfiram {u} (Compound) causes {v} (Side Effect) Tenderness
Tenderness {u} (Side Effect) is caused by {v} (Compound) Decitabine
Decitabine {u} (Compound) resembles {v} (Compound) Telbivudine
Disulfiram {u} (Compound) downregulates {v} (Gene) TYMS
TYMS {u} (Gene) is bound by {v} (Compound) Trifluridine
Trifluridine {u} (Compound) resembles {v} (Compound) Telbivudine
Disulfiram {u} (Compound) upregulates {v} (Gene) CRIP1
CRIP1 {u} (Gene) is upregulated by {v} (Compound) Trifluridine
Trifluridine {u} (Compound) resembles {v} (Compound) Telbivudine
Disulfiram {u} (Compound) upregulates {v} (Gene) CRIP1
CRIP1 {u} (Gene) is upregulated by {v} (Compound) Dexamethasone
Dexamethasone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Telbivudine
Disulfiram {u} (Compound) downregulates {v} (Gene) TYMS
TYMS {u} (Gene) is downregulated by {v} (Compound) Triamcinolone
Triamcinolone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Telbivudine
Disulfiram {u} (Compound) downregulates {v} (Gene) DDB2
DDB2 {u} (Gene) is upregulated by {v} (Compound) Trifluridine
Trifluridine {u} (Compound) resembles {v} (Compound) Telbivudine
Disulfiram {u} (Compound) upregulates {v} (Gene) CDKN1A
CDKN1A {u} (Gene) is associated with {v} (Disease) hepatitis B
hepatitis B {u} (Disease) is treated by {v} (Compound) Telbivudine
Disulfiram (Compound) causes Neuropathy peripheral (Side Effect) and Neuropathy peripheral (Side Effect) is caused by Telbivudine (Compound)
Disulfiram (Compound) causes Neuropathy peripheral (Side Effect) and Neuropathy peripheral (Side Effect) is caused by Zidovudine (Compound) and Zidovudine (Compound) resembles Telbivudine (Compound)
Disulfiram (Compound) causes Abdominal discomfort (Side Effect) and Abdominal discomfort (Side Effect) is caused by Orlistat (Compound) and Orlistat may cause a moderate interaction that could exacerbate diseases when taken with Telbivudine
Disulfiram (Compound) causes Tenderness (Side Effect) and Tenderness (Side Effect) is caused by Decitabine (Compound) and Decitabine (Compound) resembles Telbivudine (Compound)
Disulfiram (Compound) downregulates TYMS (Gene) and TYMS (Gene) is bound by Trifluridine (Compound) and Trifluridine (Compound) resembles Telbivudine (Compound)
Disulfiram (Compound) upregulates CRIP1 (Gene) and CRIP1 (Gene) is upregulated by Trifluridine (Compound) and Trifluridine (Compound) resembles Telbivudine (Compound)
Disulfiram (Compound) upregulates CRIP1 (Gene) and CRIP1 (Gene) is upregulated by Dexamethasone (Compound) and Dexamethasone may cause a moderate interaction that could exacerbate diseases when taken with Telbivudine
Disulfiram (Compound) downregulates TYMS (Gene) and TYMS (Gene) is downregulated by Triamcinolone (Compound) and Triamcinolone may cause a moderate interaction that could exacerbate diseases when taken with Telbivudine
Disulfiram (Compound) downregulates DDB2 (Gene) and DDB2 (Gene) is upregulated by Trifluridine (Compound) and Trifluridine (Compound) resembles Telbivudine (Compound)
Disulfiram (Compound) upregulates CDKN1A (Gene) and CDKN1A (Gene) is associated with hepatitis B (Disease) and hepatitis B (Disease) is treated by Telbivudine (Compound)