DDInter948 DDInter1768
Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell wall synthesis pathway.[A1279,A1281,L9068] Terbinafine hydrochloride was granted FDA approval on 30 December 1992.
Terbinafine {u} (Compound) resembles {v} (Compound) Naphazoline
Terbinafine {u} (Compound) resembles {v} (Compound) Butenafine
Terbinafine {u} (Compound) binds {v} (Gene) CYP3A4
Terbinafine {u} (Compound) upregulates {v} (Gene) NUDT3
Terbinafine {u} (Compound) is included by {v} (Pharmacologic Class) Allylamine
Terbinafine {u} (Compound) downregulates {v} (Gene) HACD3
Terbinafine {u} (Compound) causes {v} (Side Effect) Hepatic function abnormal
Terbinafine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Donepezil
Terbinafine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Tolterodine
Terbinafine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Loratadine
Terbinafine (Compound) resembles Naphazoline (Compound)
Terbinafine (Compound) resembles Butenafine (Compound)
Terbinafine (Compound) binds CYP3A4 (Gene)
Terbinafine (Compound) upregulates NUDT3 (Gene)
Terbinafine (Compound) is included by Allylamine (Pharmacologic Class)
Terbinafine (Compound) downregulates HACD3 (Gene)
Terbinafine (Compound) causes Hepatic function abnormal (Side Effect)
Terbinafine may cause a minor interaction that can limit clinical effects when taken with Donepezil
Terbinafine may cause a minor interaction that can limit clinical effects when taken with Tolterodine
Terbinafine may cause a moderate interaction that could exacerbate diseases when taken with Loratadine