DDInter1724 DDInter134
Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. It is generally given in combination with [trimethoprim], which inhibits a sequential step in bacterial folic acid synthesis - these agents work synergistically to block two consecutive steps in the biosynthesis of nucleic acids and proteins which are necessary for bacterial growth and division, and using them in conjunction helps to slow the development of bacterial resistance. In this combination, sulfamethoxazole is useful for the treatment of a variety of bacterial infections, including those of the urinary, respiratory, and gastrointestinal tracts.
Atovaquone is a hydroxynaphthoquinone, or an analog of ubiquinone, that has antimicrobial and antipneumocystis activity. It is being used in antimalarial protocols.
Sulfamethoxazole {u} (Compound) binds {v} (Gene) CYP2C9
CYP2C9 {u} (Gene) is bound by {v} (Compound) Atovaquone
Sulfamethoxazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Bicalutamide
Bicalutamide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Anisindione
Anisindione {u} (Compound) resembles {v} (Compound) Atovaquone
Sulfamethoxazole {u} (Compound) binds {v} (Gene) CYP2C9
CYP2C9 {u} (Gene) is bound by {v} (Compound) Azelastine
Azelastine {u} (Compound) resembles {v} (Compound) Atovaquone
Sulfamethoxazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Apalutamide
Apalutamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Anisindione
Anisindione {u} (Compound) resembles {v} (Compound) Atovaquone
Sulfamethoxazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Bicalutamide
Bicalutamide {u} (Compound) binds {v} (Gene) CYP2C9
CYP2C9 {u} (Gene) is bound by {v} (Compound) Atovaquone
Sulfamethoxazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Interferon beta-1a
Interferon beta-1a {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Anisindione
Anisindione {u} (Compound) resembles {v} (Compound) Atovaquone
Sulfamethoxazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Iodide I-123
Iodide I-123 {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Anisindione
Anisindione {u} (Compound) resembles {v} (Compound) Atovaquone
Sulfamethoxazole {u} may cause a minor interaction that can limit clinical effects when taken with {v} Toremifene
Toremifene {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Anisindione
Anisindione {u} (Compound) resembles {v} (Compound) Atovaquone
Sulfamethoxazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tolbutamide
Tolbutamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Anisindione
Anisindione {u} (Compound) resembles {v} (Compound) Atovaquone
Sulfamethoxazole {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Tolbutamide
Tolbutamide {u} (Compound) binds {v} (Gene) CYP2C9
CYP2C9 {u} (Gene) is bound by {v} (Compound) Atovaquone
Sulfamethoxazole (Compound) binds CYP2C9 (Gene) and CYP2C9 (Gene) is bound by Atovaquone (Compound)
Sulfamethoxazole may cause a minor interaction that can limit clinical effects when taken with Bicalutamide and Bicalutamide may cause a minor interaction that can limit clinical effects when taken with Anisindione and Anisindione (Compound) resembles Atovaquone (Compound)
Sulfamethoxazole (Compound) binds CYP2C9 (Gene) and CYP2C9 (Gene) is bound by Azelastine (Compound) and Azelastine (Compound) resembles Atovaquone (Compound)
Sulfamethoxazole may cause a minor interaction that can limit clinical effects when taken with Apalutamide and Apalutamide may cause a moderate interaction that could exacerbate diseases when taken with Anisindione and Anisindione (Compound) resembles Atovaquone (Compound)
Sulfamethoxazole may cause a minor interaction that can limit clinical effects when taken with Bicalutamide and Bicalutamide (Compound) binds CYP2C9 (Gene) and CYP2C9 (Gene) is bound by Atovaquone (Compound)
Sulfamethoxazole may cause a moderate interaction that could exacerbate diseases when taken with Interferon beta-1a and Interferon beta-1a may cause a moderate interaction that could exacerbate diseases when taken with Anisindione and Anisindione (Compound) resembles Atovaquone (Compound)
Sulfamethoxazole may cause a moderate interaction that could exacerbate diseases when taken with Iodide I-123 and Iodide I-123 may cause a moderate interaction that could exacerbate diseases when taken with Anisindione and Anisindione (Compound) resembles Atovaquone (Compound)
Sulfamethoxazole may cause a minor interaction that can limit clinical effects when taken with Toremifene and Toremifene may cause a moderate interaction that could exacerbate diseases when taken with Anisindione and Anisindione (Compound) resembles Atovaquone (Compound)
Sulfamethoxazole may cause a moderate interaction that could exacerbate diseases when taken with Tolbutamide and Tolbutamide may cause a moderate interaction that could exacerbate diseases when taken with Anisindione and Anisindione (Compound) resembles Atovaquone (Compound)
Sulfamethoxazole may cause a moderate interaction that could exacerbate diseases when taken with Tolbutamide and Tolbutamide (Compound) binds CYP2C9 (Gene) and CYP2C9 (Gene) is bound by Atovaquone (Compound)