DDInter260 DDInter1197
Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. Cabergoline possesses potent agonist activity on dopamine D2 receptors.
Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to gastroesophageal reflux disease (GERD). It can also be used to prevent nausea or vomiting associated with chemotherapy or certain surgical or diagnostic procedures. One unique property of this drug is that it does not increase gastric acid secretion. It is available in the oral tablet form or in solution, and can also be administered through the intravenous route. Metoclopramide was initially approved by the FDA in 1980.
Cabergoline {u} (Compound) binds {v} (Gene) DRD3
DRD3 {u} (Gene) is bound by {v} (Compound) Metoclopramide
Cabergoline {u} (Compound) causes {v} (Side Effect) Somnolence
Somnolence {u} (Side Effect) is caused by {v} (Compound) Metoclopramide
Cabergoline {u} (Compound) resembles {v} (Compound) Pergolide
Pergolide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Metoclopramide
Cabergoline {u} (Compound) binds {v} (Gene) DRD3
DRD3 {u} (Gene) is bound by {v} (Compound) Dopamine
Dopamine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metoclopramide
Cabergoline {u} (Compound) binds {v} (Gene) DRD2
DRD2 {u} (Gene) is bound by {v} (Compound) Cisapride
Cisapride {u} (Compound) resembles {v} (Compound) Metoclopramide
Cabergoline {u} (Compound) causes {v} (Side Effect) Somnolence
Somnolence {u} (Side Effect) is caused by {v} (Compound) Procaine
Procaine {u} (Compound) resembles {v} (Compound) Metoclopramide
Cabergoline {u} (Compound) causes {v} (Side Effect) Asthenia
Asthenia {u} (Side Effect) is caused by {v} (Compound) Sunitinib
Sunitinib {u} (Compound) resembles {v} (Compound) Metoclopramide
Cabergoline {u} (Compound) causes {v} (Side Effect) Feeling abnormal
Feeling abnormal {u} (Side Effect) is caused by {v} (Compound) Procainamide
Procainamide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Metoclopramide
Cabergoline {u} (Compound) causes {v} (Side Effect) Palpitations
Palpitations {u} (Side Effect) is caused by {v} (Compound) Dopamine
Dopamine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Metoclopramide
Cabergoline {u} (Compound) resembles {v} (Compound) Lisuride
Lisuride {u} (Compound) resembles {v} (Compound) Pergolide
Pergolide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Metoclopramide
Cabergoline (Compound) binds DRD3 (Gene) and DRD3 (Gene) is bound by Metoclopramide (Compound)
Cabergoline (Compound) causes Somnolence (Side Effect) and Somnolence (Side Effect) is caused by Metoclopramide (Compound)
Cabergoline (Compound) resembles Pergolide (Compound) and Pergolide may cause a moderate interaction that could exacerbate diseases when taken with Metoclopramide
Cabergoline (Compound) binds DRD3 (Gene) and DRD3 (Gene) is bound by Dopamine (Compound) and Dopamine may cause a minor interaction that can limit clinical effects when taken with Metoclopramide
Cabergoline (Compound) binds DRD2 (Gene) and DRD2 (Gene) is bound by Cisapride (Compound) and Cisapride (Compound) resembles Metoclopramide (Compound)
Cabergoline (Compound) causes Somnolence (Side Effect) and Somnolence (Side Effect) is caused by Procaine (Compound) and Procaine (Compound) resembles Metoclopramide (Compound)
Cabergoline (Compound) causes Asthenia (Side Effect) and Asthenia (Side Effect) is caused by Sunitinib (Compound) and Sunitinib (Compound) resembles Metoclopramide (Compound)
Cabergoline (Compound) causes Feeling abnormal (Side Effect) and Feeling abnormal (Side Effect) is caused by Procainamide (Compound) and Procainamide may cause a moderate interaction that could exacerbate diseases when taken with Metoclopramide
Cabergoline (Compound) causes Palpitations (Side Effect) and Palpitations (Side Effect) is caused by Dopamine (Compound) and Dopamine may cause a minor interaction that can limit clinical effects when taken with Metoclopramide
Cabergoline (Compound) resembles Lisuride (Compound) and Lisuride (Compound) resembles Pergolide (Compound) and Pergolide may cause a moderate interaction that could exacerbate diseases when taken with Metoclopramide