DDInter721 DDInter856
An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated heparin is more specific than LMWH for thrombin. Furthermore, the effects of UH can typically be reversed by using protamine sulfate.
Fenoprofen {u} (Compound) resembles {v} (Compound) Fenbufen
Fenoprofen {u} (Compound) binds {v} (Gene) ALB
Fenoprofen {u} (Compound) palliates {v} (Disease) osteoarthritis
Fenoprofen {u} (Compound) is included by {v} (Pharmacologic Class) Nonsteroidal Anti-inflammatory Compounds
Fenoprofen {u} (Compound) causes {v} (Side Effect) Dyspepsia
Fenoprofen (Compound) resembles Fenbufen (Compound)
Fenoprofen (Compound) binds ALB (Gene)
Fenoprofen (Compound) palliates osteoarthritis (Disease)
Fenoprofen (Compound) is included by Nonsteroidal Anti-inflammatory Compounds (Pharmacologic Class)
Fenoprofen (Compound) causes Dyspepsia (Side Effect)