DDInter885 DDInter782
Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. Hydrocortisone was granted FDA approval on 5 August 1952.
In April 2018, the U.S. Food and Drug Administration (FDA) and the Swiss company Helsinn approved the intravenous formulation of AKYNZEO® (NEPA, a fixed antiemetic combination of fosnetupitant, 235mg, and palonosetron, 0.25mg) as an alternative treatment option for patients experiencing chemotherapy-induced nausea and vomiting . Fosnetupitant is the pro-drug form of netupitant [FDA label]. Generally, 25% to 30% of patients with a diagnosis of cancer receive chemotherapy as a treatment modality and 70% to 80% of these patients undergoing chemotherapy treatment may experience nausea and vomiting as major side effects. Considered one of the most distressing side effects of chemotherapy, nausea and vomiting has an immense impact on the quality of life of patients receiving certain antineoplastic therapies .
Hydrocortisone {u} (Compound) resembles {v} (Compound) Loteprednol
Hydrocortisone {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Eplerenone
Hydrocortisone {u} (Compound) resembles {v} (Compound) Fludrocortisone
Hydrocortisone {u} (Compound) treats {v} (Disease) gout
Hydrocortisone {u} (Compound) binds {v} (Gene) CYP11B1
Hydrocortisone {u} (Compound) upregulates {v} (Gene) PRKCD
Hydrocortisone {u} (Compound) palliates {v} (Disease) prostate cancer
Hydrocortisone {u} (Compound) is included by {v} (Pharmacologic Class) Corticosteroid Hormone Receptor Agonists
Hydrocortisone {u} (Compound) downregulates {v} (Gene) AMIGO2
Hydrocortisone {u} (Compound) causes {v} (Side Effect) Papilloedema
Hydrocortisone (Compound) resembles Loteprednol (Compound)
Hydrocortisone may cause a moderate interaction that could exacerbate diseases when taken with Eplerenone
Hydrocortisone (Compound) resembles Fludrocortisone (Compound)
Hydrocortisone (Compound) treats gout (Disease)
Hydrocortisone (Compound) binds CYP11B1 (Gene)
Hydrocortisone (Compound) upregulates PRKCD (Gene)
Hydrocortisone (Compound) palliates prostate cancer (Disease)
Hydrocortisone (Compound) is included by Corticosteroid Hormone Receptor Agonists (Pharmacologic Class)
Hydrocortisone (Compound) downregulates AMIGO2 (Gene)
Hydrocortisone (Compound) causes Papilloedema (Side Effect)