DDInter948 DDInter1431
Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Perindopril may be used to treat mild to moderate essential hypertension, mild to moderate congestive heart failure, and to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and stable coronary disease.
Perindopril {u} (Compound) resembles {v} (Compound) Trandolapril
Perindopril {u} (Compound) resembles {v} (Compound) Quinapril
Perindopril {u} (Compound) treats {v} (Disease) coronary artery disease
Perindopril {u} (Compound) binds {v} (Gene) ACE
Perindopril {u} (Compound) upregulates {v} (Gene) SATB1
Perindopril {u} (Compound) downregulates {v} (Gene) HAT1
Perindopril {u} (Compound) causes {v} (Side Effect) Muscular weakness
Perindopril {u} may cause a minor interaction that can limit clinical effects when taken with {v} Magnesium carbonate
Perindopril {u} may cause a minor interaction that can limit clinical effects when taken with {v} Erythropoietin
Perindopril {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Epoprostenol
Perindopril (Compound) resembles Trandolapril (Compound)
Perindopril (Compound) resembles Quinapril (Compound)
Perindopril (Compound) treats coronary artery disease (Disease)
Perindopril (Compound) binds ACE (Gene)
Perindopril (Compound) upregulates SATB1 (Gene)
Perindopril (Compound) downregulates HAT1 (Gene)
Perindopril (Compound) causes Muscular weakness (Side Effect)
Perindopril may cause a minor interaction that can limit clinical effects when taken with Magnesium carbonate
Perindopril may cause a minor interaction that can limit clinical effects when taken with Erythropoietin
Perindopril may cause a moderate interaction that could exacerbate diseases when taken with Epoprostenol