DDInter883 DDInter1180
Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension.[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors[L8390,L8423] or angiotensin II receptor blockers.[L7426,L7459] Hydrochlorothiazide was granted FDA approval on 12 February 1959.
Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Hydrochlorothiazide {u} (Compound) resembles {v} (Compound) Diclofenamide
Hydrochlorothiazide {u} (Compound) resembles {v} (Compound) Polythiazide
Hydrochlorothiazide {u} (Compound) treats {v} (Disease) nephrolithiasis
Hydrochlorothiazide {u} (Compound) binds {v} (Gene) CA5B
Hydrochlorothiazide {u} (Compound) upregulates {v} (Gene) ABHD6
Hydrochlorothiazide {u} (Compound) is included by {v} (Pharmacologic Class) Thiazides
Hydrochlorothiazide {u} (Compound) downregulates {v} (Gene) GDF15
Hydrochlorothiazide {u} (Compound) causes {v} (Side Effect) Mood swings
Hydrochlorothiazide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Scopolamine
Hydrochlorothiazide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Minocycline
Hydrochlorothiazide (Compound) resembles Diclofenamide (Compound)
Hydrochlorothiazide (Compound) resembles Polythiazide (Compound)
Hydrochlorothiazide (Compound) treats nephrolithiasis (Disease)
Hydrochlorothiazide (Compound) binds CA5B (Gene)
Hydrochlorothiazide (Compound) upregulates ABHD6 (Gene)
Hydrochlorothiazide (Compound) is included by Thiazides (Pharmacologic Class)
Hydrochlorothiazide (Compound) downregulates GDF15 (Gene)
Hydrochlorothiazide (Compound) causes Mood swings (Side Effect)
Hydrochlorothiazide may cause a minor interaction that can limit clinical effects when taken with Scopolamine
Hydrochlorothiazide may cause a minor interaction that can limit clinical effects when taken with Minocycline