DDInter268 DDInter1861
Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D<sub>3</sub>, 1,25-dihydroxyvitamin D<sub>3</sub>. It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to (vitamin D3) in the skin, which is then converted to in the liver and kidneys. undergoes hydroxylation to form calcitriol via 1α-hydroxylase (CYP27B1) activity. Calcitriol is considered to be the most potent metabolite of vitamin D in humans. Renal production of calcitriol is stimulated in response to PTH
A thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p830)
Calcitriol {u} (Compound) resembles {v} (Compound) Paricalcitol
Paricalcitol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Trichlormethiazide
Calcitriol {u} (Compound) resembles {v} (Compound) Paricalcitol
Paricalcitol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Benzthiazide
Benzthiazide {u} (Compound) resembles {v} (Compound) Trichlormethiazide
Calcitriol {u} (Compound) resembles {v} (Compound) Cholecalciferol
Cholecalciferol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Benzthiazide
Benzthiazide {u} (Compound) resembles {v} (Compound) Trichlormethiazide
Calcitriol {u} (Compound) causes {v} (Side Effect) Asthenia
Asthenia {u} (Side Effect) is caused by {v} (Compound) Polythiazide
Polythiazide {u} (Compound) resembles {v} (Compound) Trichlormethiazide
Calcitriol {u} (Compound) resembles {v} (Compound) Paricalcitol
Paricalcitol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Polythiazide
Polythiazide {u} (Compound) resembles {v} (Compound) Trichlormethiazide
Calcitriol {u} (Compound) causes {v} (Side Effect) Asthenia
Asthenia {u} (Side Effect) is caused by {v} (Compound) Chlorothiazide
Chlorothiazide {u} (Compound) resembles {v} (Compound) Trichlormethiazide
Calcitriol {u} (Compound) resembles {v} (Compound) Paricalcitol
Paricalcitol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Magnesium citrate
Magnesium citrate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Trichlormethiazide
Calcitriol {u} (Compound) resembles {v} (Compound) Calcifediol
Calcifediol {u} (Compound) downregulates {v} (Gene) CDC20
CDC20 {u} (Gene) is downregulated by {v} (Compound) Trichlormethiazide
Calcitriol {u} (Compound) resembles {v} (Compound) Paricalcitol
Paricalcitol {u} may lead to a major life threatening interaction when taken with {v} Cholecalciferol
Cholecalciferol {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Trichlormethiazide
Calcitriol {u} (Compound) causes {v} (Side Effect) Urticaria
Urticaria {u} (Side Effect) is caused by {v} (Compound) Dicyclomine
Dicyclomine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Trichlormethiazide
Calcitriol (Compound) resembles Paricalcitol (Compound) and Paricalcitol may cause a moderate interaction that could exacerbate diseases when taken with Trichlormethiazide
Calcitriol (Compound) resembles Paricalcitol (Compound) and Paricalcitol may cause a moderate interaction that could exacerbate diseases when taken with Benzthiazide and Benzthiazide (Compound) resembles Trichlormethiazide (Compound)
Calcitriol (Compound) resembles Cholecalciferol (Compound) and Cholecalciferol may cause a moderate interaction that could exacerbate diseases when taken with Benzthiazide and Benzthiazide (Compound) resembles Trichlormethiazide (Compound)
Calcitriol (Compound) causes Asthenia (Side Effect) and Asthenia (Side Effect) is caused by Polythiazide (Compound) and Polythiazide (Compound) resembles Trichlormethiazide (Compound)
Calcitriol (Compound) resembles Paricalcitol (Compound) and Paricalcitol may cause a moderate interaction that could exacerbate diseases when taken with Polythiazide and Polythiazide (Compound) resembles Trichlormethiazide (Compound)
Calcitriol (Compound) causes Asthenia (Side Effect) and Asthenia (Side Effect) is caused by Chlorothiazide (Compound) and Chlorothiazide (Compound) resembles Trichlormethiazide (Compound)
Calcitriol (Compound) resembles Paricalcitol (Compound) and Paricalcitol may cause a moderate interaction that could exacerbate diseases when taken with Magnesium citrate and Magnesium citrate may cause a moderate interaction that could exacerbate diseases when taken with Trichlormethiazide
Calcitriol (Compound) resembles Calcifediol (Compound) and Calcifediol (Compound) downregulates CDC20 (Gene) and CDC20 (Gene) is downregulated by Trichlormethiazide (Compound)
Calcitriol (Compound) resembles Paricalcitol (Compound) and Paricalcitol may lead to a major life threatening interaction when taken with Cholecalciferol and Cholecalciferol may cause a moderate interaction that could exacerbate diseases when taken with Trichlormethiazide
Calcitriol (Compound) causes Urticaria (Side Effect) and Urticaria (Side Effect) is caused by Dicyclomine (Compound) and Dicyclomine may cause a minor interaction that can limit clinical effects when taken with Trichlormethiazide