DDInter1191 DDInter1371
Methylprednisolone is a [prednisolone] derivative glucocorticoid with higher potency than [prednisone]. It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with long-term immunosuppression. The efficacy of methylprednisolone in novel coronavirus pneumonia is being investigated further in clinical trials.
Oxymetholone is a synthetic anabolic steroid marketed under the brand name Anapolon by Hoffmann La Roche Limitedand used in the treatment of osteoporosis, anaemia, and as an agent to stimulate muscle growth in malnourished or underdeveloped patients. Anabolic-androgenic steroids (AAS), such as oxymetholone, have been abused by bodybuilders and athletes. The uncontrolled misuse of oxymetholone can lead to a large variety of detrimental effects, the most often reported of which are cardiovascular events. In 2009, no producers of oxymetholone were identified worldwide (SRI 2009), but it was available from 14 suppliers, including 8 U.S. suppliers (ChemSources 2009).
Methylprednisolone {u} (Compound) resembles {v} (Compound) Halobetasol Propionate
Methylprednisolone {u} (Compound) resembles {v} (Compound) Testolactone
Methylprednisolone {u} (Compound) treats {v} (Disease) rheumatoid arthritis
Methylprednisolone {u} (Compound) binds {v} (Gene) CYP3A4
Methylprednisolone {u} (Compound) upregulates {v} (Gene) ZFP36
Methylprednisolone {u} (Compound) palliates {v} (Disease) hematologic cancer
Methylprednisolone {u} (Compound) is included by {v} (Pharmacologic Class) Corticosteroid Hormone Receptor Agonists
Methylprednisolone {u} (Compound) downregulates {v} (Gene) FOSL1
Methylprednisolone {u} (Compound) causes {v} (Side Effect) Diplegia
Methylprednisolone {u} may cause a minor interaction that can limit clinical effects when taken with {v} Isoniazid
Methylprednisolone (Compound) resembles Halobetasol Propionate (Compound)
Methylprednisolone (Compound) resembles Testolactone (Compound)
Methylprednisolone (Compound) treats rheumatoid arthritis (Disease)
Methylprednisolone (Compound) binds CYP3A4 (Gene)
Methylprednisolone (Compound) upregulates ZFP36 (Gene)
Methylprednisolone (Compound) palliates hematologic cancer (Disease)
Methylprednisolone (Compound) is included by Corticosteroid Hormone Receptor Agonists (Pharmacologic Class)
Methylprednisolone (Compound) downregulates FOSL1 (Gene)
Methylprednisolone (Compound) causes Diplegia (Side Effect)
Methylprednisolone may cause a minor interaction that can limit clinical effects when taken with Isoniazid