DDInter1374 DDInter1853
A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.
Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin A] (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant, and free radical-scavenging activities. It has been used in dermatology for many years to treat various skin conditions ranging from acne to wrinkles [A257474,A258185] and activates nuclear receptors to regulate epithelial cell growth and differentiation.[A257474,A257629,A257609] Tretinoin is given orally to treat acute promyelocytic leukemia and topically to treat skin conditions such as acne.[L45389,L34869,L45384]
Oxytetracycline {u} may lead to a major life threatening interaction when taken with {v} Isotretinoin
Isotretinoin {u} (Compound) resembles {v} (Compound) Tretinoin
Oxytetracycline {u} may lead to a major life threatening interaction when taken with {v} Acitretin
Acitretin {u} (Compound) resembles {v} (Compound) Tretinoin
Oxytetracycline {u} may lead to a major life threatening interaction when taken with {v} Isotretinoin
Isotretinoin {u} (Compound) resembles {v} (Compound) Vitamin A
Vitamin A {u} (Compound) resembles {v} (Compound) Tretinoin
Oxytetracycline {u} (Compound) resembles {v} (Compound) Doxycycline
Doxycycline {u} (Compound) binds {v} (Gene) CYP3A4
CYP3A4 {u} (Gene) is bound by {v} (Compound) Tretinoin
Oxytetracycline {u} may lead to a major life threatening interaction when taken with {v} Acitretin
Acitretin {u} may lead to a major life threatening interaction when taken with {v} Isotretinoin
Isotretinoin {u} (Compound) resembles {v} (Compound) Tretinoin
Oxytetracycline {u} may lead to a major life threatening interaction when taken with {v} Isotretinoin
Isotretinoin {u} may lead to a major life threatening interaction when taken with {v} Acitretin
Acitretin {u} (Compound) resembles {v} (Compound) Tretinoin
Oxytetracycline {u} (Compound) resembles {v} (Compound) Doxycycline
Doxycycline {u} may lead to a major life threatening interaction when taken with {v} Isotretinoin
Isotretinoin {u} (Compound) resembles {v} (Compound) Tretinoin
Oxytetracycline {u} may lead to a major life threatening interaction when taken with {v} Acitretin
Acitretin {u} (Compound) resembles {v} (Compound) Vitamin A
Vitamin A {u} (Compound) resembles {v} (Compound) Tretinoin
Oxytetracycline {u} may lead to a major life threatening interaction when taken with {v} Isotretinoin
Isotretinoin {u} (Compound) treats {v} (Disease) peripheral nervous system neoplasm
peripheral nervous system neoplasm {u} (Disease) is treated by {v} (Compound) Tretinoin
Oxytetracycline {u} (Compound) resembles {v} (Compound) Minocycline
Minocycline {u} (Compound) binds {v} (Gene) IL1B
IL1B {u} (Gene) is upregulated by {v} (Compound) Tretinoin
Oxytetracycline may lead to a major life threatening interaction when taken with Isotretinoin and Isotretinoin (Compound) resembles Tretinoin (Compound)
Oxytetracycline may lead to a major life threatening interaction when taken with Acitretin and Acitretin (Compound) resembles Tretinoin (Compound)
Oxytetracycline may lead to a major life threatening interaction when taken with Isotretinoin and Isotretinoin (Compound) resembles Vitamin A (Compound) and Vitamin A (Compound) resembles Tretinoin (Compound)
Oxytetracycline (Compound) resembles Doxycycline (Compound) and Doxycycline (Compound) binds CYP3A4 (Gene) and CYP3A4 (Gene) is bound by Tretinoin (Compound)
Oxytetracycline may lead to a major life threatening interaction when taken with Acitretin and Acitretin may lead to a major life threatening interaction when taken with Isotretinoin and Isotretinoin (Compound) resembles Tretinoin (Compound)
Oxytetracycline may lead to a major life threatening interaction when taken with Isotretinoin and Isotretinoin may lead to a major life threatening interaction when taken with Acitretin and Acitretin (Compound) resembles Tretinoin (Compound)
Oxytetracycline (Compound) resembles Doxycycline (Compound) and Doxycycline may lead to a major life threatening interaction when taken with Isotretinoin and Isotretinoin (Compound) resembles Tretinoin (Compound)
Oxytetracycline may lead to a major life threatening interaction when taken with Acitretin and Acitretin (Compound) resembles Vitamin A (Compound) and Vitamin A (Compound) resembles Tretinoin (Compound)
Oxytetracycline may lead to a major life threatening interaction when taken with Isotretinoin and Isotretinoin (Compound) treats peripheral nervous system neoplasm (Disease) and peripheral nervous system neoplasm (Disease) is treated by Tretinoin (Compound)
Oxytetracycline (Compound) resembles Minocycline (Compound) and Minocycline (Compound) binds IL1B (Gene) and IL1B (Gene) is upregulated by Tretinoin (Compound)