DDInter1174 DDInter957
Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and non-Hodgkin's lymphoma.[A180322,L7144,L7147,L7150,L7180] Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and severe psoriasis only if first line treatment has failed or patients are intolerant of those treatments. Methotrexate was granted FDA approval on 7 December 1953.
Iodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.
Methotrexate {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Methotrexate {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Methotrexate {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Diatrizoate
Diatrizoate {u} (Compound) resembles {v} (Compound) Iodipamide
Methotrexate {u} may lead to a major life threatening interaction when taken with {v} Piroxicam
Piroxicam {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Methotrexate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Vemurafenib
Vemurafenib {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Methotrexate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Vemurafenib
Vemurafenib {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Methotrexate {u} may lead to a major life threatening interaction when taken with {v} Ibuprofen
Ibuprofen {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Methotrexate {u} may lead to a major life threatening interaction when taken with {v} Ibuprofen
Ibuprofen {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Methotrexate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Gefitinib
Gefitinib {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Methotrexate {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Gefitinib
Gefitinib {u} (Compound) causes {v} (Side Effect) Body temperature increased
Body temperature increased {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Methotrexate (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Methotrexate (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Iodipamide (Compound)
Methotrexate (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Diatrizoate (Compound) and Diatrizoate (Compound) resembles Iodipamide (Compound)
Methotrexate may lead to a major life threatening interaction when taken with Piroxicam and Piroxicam (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Methotrexate may cause a moderate interaction that could exacerbate diseases when taken with Vemurafenib and Vemurafenib (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Methotrexate may cause a moderate interaction that could exacerbate diseases when taken with Vemurafenib and Vemurafenib (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Iodipamide (Compound)
Methotrexate may lead to a major life threatening interaction when taken with Ibuprofen and Ibuprofen (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Methotrexate may lead to a major life threatening interaction when taken with Ibuprofen and Ibuprofen (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Iodipamide (Compound)
Methotrexate may cause a moderate interaction that could exacerbate diseases when taken with Gefitinib and Gefitinib (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Methotrexate may cause a moderate interaction that could exacerbate diseases when taken with Gefitinib and Gefitinib (Compound) causes Body temperature increased (Side Effect) and Body temperature increased (Side Effect) is caused by Iodipamide (Compound)