DDInter532 DDInter1376
Diamorphine (heroin) is a narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S. Code of Federal Regulations, Title 21 Parts 329.1, 1308.11 (1987). Sale is forbidden in the United States by Federal statute. (Merck Index, 11th ed) Internationally, diamorphine is controlled under Schedules I and IV of the Single Convention on Narcotic Drugs. As heroin, it is illegal to manufacture, possess, or sell in the United States and the UK. However, under the name diamorphine, heroin is a legal prescription drug in the United Kingdom.
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26, 2020.[L12573,L12582] The US approval was followed by the approval in Canada on October 2, 2020. In November 2021, ozanimod was also approved by the European Commission for the treatment of adults with relapsing remitting multiple sclerosis.[L39377,L39382] MS is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Inflammatory bowel disease also a chronic inflammatory condition and can cause persistent abdominal pain, diarrhea, bloody stools, and vomiting. In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard in MS therapy. Studies involving patients with inflammatory bowel disease have also shown promising results.[A189318,A189342]
Diamorphine {u} (Compound) resembles {v} (Compound) Codeine
Diamorphine {u} (Compound) resembles {v} (Compound) Ethylmorphine
Diamorphine {u} may lead to a major life threatening interaction when taken with {v} Morphine
Diamorphine {u} (Compound) binds {v} (Gene) OPRK1
Diamorphine {u} may cause a minor interaction that can limit clinical effects when taken with {v} Ephedrine
Diamorphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Amyl Nitrite
Diamorphine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Cyproheptadine
Diamorphine {u} may lead to a major life threatening interaction when taken with {v} Methylene blue
Diamorphine (Compound) resembles Codeine (Compound)
Diamorphine (Compound) resembles Ethylmorphine (Compound)
Diamorphine may lead to a major life threatening interaction when taken with Morphine
Diamorphine (Compound) binds OPRK1 (Gene)
Diamorphine may cause a minor interaction that can limit clinical effects when taken with Ephedrine
Diamorphine may cause a moderate interaction that could exacerbate diseases when taken with Amyl Nitrite
Diamorphine may cause a moderate interaction that could exacerbate diseases when taken with Cyproheptadine
Diamorphine may lead to a major life threatening interaction when taken with Methylene blue