DDInter1725 DDInter957
Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs. It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA).[L39065, A255582] Metabolized by intestinal bacteria, sulfasalazine is broken down into [mesalazine] and [sulfapyridine], 2 compounds that carry out the main pharmacological activity of sulfasalazine. Sulfasalazine was first used in 1940 for rheumatic polyarthritis, and has been firmly established itself as one fo the most useful disease-modifying antirheumatic drug (DMARD). Compared to the first line treatment of RA like methotrexate, sulfasalazine is almost as efficacious as methotrexate although with slightly less tolerability. However, sulfasalazine has less teratogenic side effects and faster onset of action compared to conventional DMARD. Sulf
Iodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.
Sulfasalazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Piroxicam
Piroxicam {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Sulfasalazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Repaglinide
Repaglinide {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Sulfasalazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Repaglinide
Repaglinide {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Sulfasalazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Nateglinide
Nateglinide {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Sulfasalazine {u} (Compound) resembles {v} (Compound) Vismodegib
Vismodegib {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Sulfasalazine {u} (Compound) resembles {v} (Compound) Vismodegib
Vismodegib {u} (Compound) causes {v} (Side Effect) Nausea
Nausea {u} (Side Effect) is caused by {v} (Compound) Iodipamide
Sulfasalazine {u} may lead to a major life threatening interaction when taken with {v} Warfarin
Warfarin {u} (Compound) binds {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Sulfasalazine {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Estradiol
Estradiol {u} (Compound) downregulates {v} (Gene) GRB7
GRB7 {u} (Gene) is downregulated by {v} (Compound) Iodipamide
Sulfasalazine {u} (Compound) treats {v} (Disease) ulcerative colitis
ulcerative colitis {u} (Disease) is associated with {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Sulfasalazine {u} (Compound) binds {v} (Gene) CHUK
CHUK {u} (Gene) is regulated by {v} (Gene) ALB
ALB {u} (Gene) is bound by {v} (Compound) Iodipamide
Sulfasalazine may cause a moderate interaction that could exacerbate diseases when taken with Piroxicam and Piroxicam (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Sulfasalazine may cause a moderate interaction that could exacerbate diseases when taken with Repaglinide and Repaglinide (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Sulfasalazine may cause a moderate interaction that could exacerbate diseases when taken with Repaglinide and Repaglinide (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Iodipamide (Compound)
Sulfasalazine may cause a moderate interaction that could exacerbate diseases when taken with Nateglinide and Nateglinide (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Iodipamide (Compound)
Sulfasalazine (Compound) resembles Vismodegib (Compound) and Vismodegib (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Sulfasalazine (Compound) resembles Vismodegib (Compound) and Vismodegib (Compound) causes Nausea (Side Effect) and Nausea (Side Effect) is caused by Iodipamide (Compound)
Sulfasalazine may lead to a major life threatening interaction when taken with Warfarin and Warfarin (Compound) binds ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Sulfasalazine may cause a moderate interaction that could exacerbate diseases when taken with Estradiol and Estradiol (Compound) downregulates GRB7 (Gene) and GRB7 (Gene) is downregulated by Iodipamide (Compound)
Sulfasalazine (Compound) treats ulcerative colitis (Disease) and ulcerative colitis (Disease) is associated with ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)
Sulfasalazine (Compound) binds CHUK (Gene) and CHUK (Gene) is regulated by ALB (Gene) and ALB (Gene) is bound by Iodipamide (Compound)