DDInter580 DDInter1016
Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration (FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation and flutter, and for the chemical cardioversion to sinus rhythm from atrial fibrillation and flutter.
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose]. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. [sucrose]). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in patients with cirrhosis.[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.
Dofetilide {u} (Compound) resembles {v} (Compound) Dronedarone
Dofetilide {u} (Compound) resembles {v} (Compound) Rosiglitazone
Dofetilide {u} (Compound) binds {v} (Gene) KCNH2
Dofetilide {u} (Compound) upregulates {v} (Gene) CASP7
Dofetilide {u} (Compound) downregulates {v} (Gene) CDCA4
Dofetilide {u} (Compound) causes {v} (Side Effect) Dyspnoea
Dofetilide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Bexarotene
Dofetilide {u} may cause a minor interaction that can limit clinical effects when taken with {v} Troglitazone
Dofetilide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Chloramphenicol
Dofetilide {u} may cause a moderate interaction that could exacerbate diseases when taken with {v} Octreotide
Dofetilide (Compound) resembles Dronedarone (Compound)
Dofetilide (Compound) resembles Rosiglitazone (Compound)
Dofetilide (Compound) binds KCNH2 (Gene)
Dofetilide (Compound) upregulates CASP7 (Gene)
Dofetilide (Compound) downregulates CDCA4 (Gene)
Dofetilide (Compound) causes Dyspnoea (Side Effect)
Dofetilide may cause a minor interaction that can limit clinical effects when taken with Bexarotene
Dofetilide may cause a minor interaction that can limit clinical effects when taken with Troglitazone
Dofetilide may cause a moderate interaction that could exacerbate diseases when taken with Chloramphenicol
Dofetilide may cause a moderate interaction that could exacerbate diseases when taken with Octreotide