text:
Differential recognition of sequences within the encephalitogenic region of myelin basic protein capable of eliciting cell-mediated immune responses in experimental autoimmune encephalomyelitis.
The fine specificity of myelin basic protein (MBP) epitopes capable of eliciting in vivo delayed-type hypersensitivity responses in Lewis rats with experimental autoimmune encephalomyelitis (EAE) was compared to those eliciting in vitro antigen-specific T cell proliferation and augmentation of disease transfer. Utilizing a panel of synthetic peptides with sequences representing the 68-86 region of guinea pig (GP-) or bovine myelin basic protein (B-MBP), animals were primed with one species of peptide and subsequently challenged with either the same peptide or peptides with truncations or substitutions representative of the other species of MBP. In regard to minimal length sequences capable of eliciting delayed-type hypersensitivity (DTH), rats primed with GP-MBP and complete Freund's adjuvant (CFA) exhibited a hierarchical pattern of responsiveness to challenge with a series of truncated peptides, ranking as follows: GP-68-86 > GP-72-86 > GP-68-84 > > GP-75-86 = no activity. This response pattern corresponds to that previously reported for T cell proliferation and activation for disease transfer. Furthermore, a comparison of these T cell-mediated immune parameters, as elicited by the substituted peptides, revealed the response patterns of DTH reactivity to be similar to that previously described for in vitro T cell proliferation with significant DTH responses generated only by the peptide species for which the animal was primed. In contrast, a cross-reactive pattern of recognition was observed in cells mediating disease transfer, with all four 68-86 sequences capable of augmenting activation for adoptive transfer of disease, regardless of the peptide species for which the animal was primed.(ABSTRACT TRUNCATED AT 250 WORDS)

textbook:
Lesson: Understanding Differential Recognition of Sequences Within the Encephalitogenic Region of Myelin Basic Protein

### Overview
In this lesson, we will explore the concept of differential recognition of sequences within the encephalitogenic region of myelin basic protein (MBP). We will cover the following topics:

1. What is MBP and its role in the body?
2. The encephalitogenic region of MBP
3. Differential recognition of sequences within the encephalitogenic region of MBP
4. Experimental autoimmune encephalomyelitis (EAE)
5. Conclusion

### Section 1: What is MBP and its role in the body?
Myelin basic protein (MBP) is a protein found in the body's nervous system. It plays a crucial role in the formation and maintenance of the myelin sheath, which is a fatty substance that surrounds and insulates nerve fibers. The myelin sheath is essential for the proper functioning of the nervous system as it allows for efficient transmission of electrical signals along the nerve fibers.

### Section 2: The encephalitogenic region of MBP
The encephalitogenic region of MBP refers to a specific part of the protein that is responsible for triggering an autoimmune response in the body. This region of the protein is capable of eliciting cell-mediated immune responses, which can lead to inflammation and damage to the myelin sheath.

### Section 3: Differential recognition of sequences within the encephalitogenic region of MBP
Research has shown that different sequences within the encephalitogenic region of MBP can be recognized differentially by the immune system. This means that certain sequences are more likely to trigger an autoimmune response than others. This differential recognition is thought to be due to the fact that the immune system can recognize a vast number of different peptides within the encephalitogenic region of MBP, and some of these peptides are more likely to be recognized and trigger an immune response than others.

### Section 4: Experimental autoimmune encephalomyelitis (EAE)
Experimental autoimmune encephalomyelitis (EAE) is a model of multiple sclerosis, a chronic autoimmune disease that affects the central nervous system. EAE is induced in rodents by immunization with MBP or related proteins. The disease is characterized by demyelination, inflammation, and tissue damage in the central nervous system, which can lead to paralysis and other neurological deficits.

### Section 5: Conclusion
Understanding the differential recognition of sequences within the encephalitogenic region of MBP is important for understanding the pathogenesis of autoimmune diseases like multiple sclerosis. By identifying the specific sequences that are more likely to trigger an autoimmune response, researchers can develop targeted therapies to prevent or treat these diseases. Additionally, this knowledge can help us understand how the immune system recognizes and responds to different peptides within the encephalitogenic region of MBP, which could have broader implications for understanding the immune system as a whole.


text: Smart Track Chapter Modules. Chapter educational offerings: If your chapter is looking for a convenient.. Chapters: Borrow, buy or rent Gold Standard banners. Perfect for real estate and consumer shows or for any opportunity to promote ASHI, these new banners now are available to chapters for only the shipping costs. Members also may rent a banner for shipping costs and a small fee.. To reserve a banner, download and return the form.. In addition to the ASHI banners, customized versions are available. Email Russell Daniels at russelld@ashi.org to learn more.. Online resources. Access ASHI chapter resources here. You'll find public relations and marketing materials, chapter recruitment tools, leadership resources, legislative tools and more.. Questions?. If you have questions about ASHI chapters contact Russell Daniels, ASHI director of chapter relations, at russelld@ashi.org or 847-954-3185 or email hq@ashi.org.

source: refinedweb

textbook:
Lesson: Introduction to ASHI Chapters

## Section 1: What are ASHI Chapters?
ASHI (American Society of Home Inspectors) is a professional association that represents home inspectors across the United States. One of the key components of ASHI is its chapters. These chapters are local organizations that provide support, resources, and networking opportunities for home inspectors in their area.

## Section 2: Purpose of ASHI Chapters
The primary purpose of ASHI chapters is to provide a platform for home inspectors to come together, share knowledge, and improve the overall quality of the profession. This is achieved through various means such as educational events, networking opportunities, and advocacy efforts.

## Section 3: Types of Resources Available Through ASHI Chapters
ASHI chapters offer a wide range of resources to their members, including:

1. Educational Events: ASHI chapters often host educational events, where members can learn about the latest industry trends, techniques, and technologies.

2. Networking Opportunities: Chapters provide members with opportunities to connect with other home inspectors in their area, allowing them to build relationships and share knowledge.

3. Advocacy Efforts: ASHI chapters work to promote the interests of home inspectors at the local, state, and national levels, ensuring that their voices are heard in policy debates.

4. Access to Online Resources: ASHI provides chapters with access to a variety of online resources, including marketing materials, leadership resources, and legislative tools.

## Section 4: Customized Banners
ASHI chapters can now purchase or rent banners featuring the ASHI logo and messaging. These banners are perfect for promoting the organization at real estate and consumer shows, or for any other occasion where visibility is important.

## Conclusion
By understanding the purpose and resources available through ASHI chapters, home inspectors can take advantage of these opportunities to improve their skills, network with others in the industry, and advocate for their profession. This knowledge can help them become better inspectors and better representatives of the ASHI brand.


text: Thursday, August 30, 2007. Thursday, August 2, 2007. Wednesday, August 1, 2007. Club Penguin. Just announced today. Disney bought Club Penguin for $700M with $350M up front and $350M incentive based.. If you look at the numbers (700k paying subscribers at ~$6/month), the site is generating $4.2M/month or $50.4M/year-ish in revenue so the valuation isn't completely unreasonable, especially if they can grow.. My kids play this game and love it, but my 7 year old daughter decided that she didn't need her subscription after playing it for a month...

textbook:
Lesson: Introduction to Financial Analysis

## Section 1: Theoretical Concepts
In this lesson, we will learn about financial analysis, which is the process of evaluating a company's financial performance and health. We will cover the following concepts:

1. Revenue: This refers to the money a company earns from selling products or services. It is one of the most important metrics used to evaluate a company's financial performance.

2. Earnings: This refers to the profit a company makes after deducting all expenses, including taxes and interest. It is also known as net income.

3. Net Present Value (NPV): This is a financial metric that calculates the potential profitability of an investment or project. It takes into account the time value of money, which means that money earned today is worth more than money earned in the future due to its potential earning capacity.

4. Return on Investment (ROI): This is a measure of a company's efficiency in using its assets to generate profits. It is calculated by dividing the profit made by the cost of the investment.

5. Debt-to-Equity Ratio: This is a financial ratio that compares a company's total debt to its shareholder equity. It is used to determine how much of a company's financing comes from debt and how much comes from shareholder investments.

## Section 2: Practical Examples
Now that we understand the theoretical concepts, let's look at some practical examples using mathematical abstractions and real-world scenarios.

Example 1: Suppose a company has a revenue of $10 million and a profit margin of 10%. What is its net income?

Solution: To calculate the net income, we need to subtract all expenses from the revenue. Let's assume that the company's expenses are $8 million. Therefore, the net income would be:

Net Income = Revenue - Expenses
Net Income = $10 million - $8 million
Net Income = $2 million

Example 2: A company wants to invest in a new project that requires an initial investment of $100,000. The project is expected to generate a profit of $20,000 per year for the next 5 years. What is the Net Present Value (NPV) of this project?

Solution: To calculate the NPV, we need to discount the cash flows generated by the project. We will use a discount rate of 10% for this calculation. The formula for calculating NPV is:

NPV = Initial Investment + [Cash Flow / (1 + Discount Rate)^Years] * Years

Using this formula, we get:

NPV = $100,000 + [($20,000 / (1 + 0.10)^5) * 5]
NPV = $100,000 + [($20,000 / 1.576) * 5]
NPV = $100,000 + [$12,495.81 * 5]
NPV = $100,000 + $62,479.05
NPV = $162,479.05

Therefore, the NPV of this project is $162,479.05.

## Section 3: Self-Debating Discussions
Let's engage in a self-debating discussion to teach critical thinking.

Question: Should a company focus on increasing its revenue or decreasing its expenses to improve its profitability?

Answer: Both increasing revenue and decreasing expenses are important for improving profitability. However, a company should first focus on increasing its profit margin by reducing expenses. This will result in a higher net income, which can then be reinvested in the business to generate even more revenue.

## Glossary
- Revenue: The money a company earns from selling products or services.
- Earnings: The profit a company makes after deducting all expenses, including taxes and interest.
- Net Present Value (NPV): A financial metric that calculates the potential profitability of an investment or project.
- Return on Investment (ROI): A measure of a company's efficiency in using its assets to generate profits.
- Debt-to-Equity Ratio: A financial ratio that compares a company's total debt to its shareholder equity.

## Conclusion
In this lesson, we learned about financial analysis, including revenue, earnings, net present value, return on investment, and debt-to-equity ratio. We also looked at practical examples using mathematical abstractions and real-world scenarios. Finally, we engaged in a self-debating discussion to teach critical thinking. By understanding these concepts, we can apply them to new problems and make informed decisions about financial matters.


text:
DNotes Global Inc. has announced that the upgraded DNotes 2.0 CRISP program has successfully delivered its first payments to DNotes stakeholders. The payments were delivered on June 10 to DNotesVault users who had stored coins in the secure DNotes vault from April 30 to June 3, 2018.

Mission Statement

DCEBrief is committed to focus on bringing issues that matter to your attention, utilizing an “Executive Summary” without fluff and filler. When appropriate, we may also include full length articles. Our mission is to keep you informed with timely information. We will need the cooperation of the mainstream media and the full support of our political leaders and regulators to help promote and not stifle innovation for the better good of mankind.

source: minipile

textbook:
Lesson: Introduction to Cryptocurrency and Blockchain Technology

## Section 1: What is Cryptocurrency?
Cryptocurrency is a digital or virtual currency that uses cryptography for security. It operates on a decentralized network called blockchain technology, which allows transactions to be verified by network nodes and recorded in a public ledger. Cryptocurrencies are not controlled by any central authority, making them resistant to government intervention and inflation.

## Section 2: How does Blockchain Technology work?
Blockchain technology is a distributed ledger that records all transactions made within a network. It consists of a chain of blocks, each containing a list of transactions. Once a block is added to the chain, it cannot be altered or deleted. Blocks are added to the chain using a consensus mechanism, where network nodes must agree on the validity of a transaction before it is added to the blockchain.

## Section 3: Why use Cryptocurrency?
Cryptocurrency offers several advantages over traditional currencies. It is secure, as transactions are encrypted and cannot be tampered with. It is also transparent, as all transactions are recorded on a public ledger. Additionally, cryptocurrency transactions are fast and cheap, as they do not require intermediaries such as banks.

## Section 4: Real-world applications of Cryptocurrency
Cryptocurrency has several real-world applications, including online purchases, money transfers, and investment. It can also be used to create smart contracts, which are self-executing contracts with the terms of the agreement between buyer and seller being directly written into lines of code.

## Section 5: Conclusion
Understanding cryptocurrency and blockchain technology is essential in today's digital age. As more businesses and individuals adopt this technology, it is crucial to have a solid understanding of how it works and its potential benefits. By applying the knowledge gained from this lesson, individuals can make informed decisions about investing in cryptocurrency and using it for various purposes.

## Glossary:
- Cryptocurrency: A digital or virtual currency that uses cryptography for security.
- Blockchain technology: A decentralized network that records transactions in a public ledger.
- Consensus mechanism: A process where network nodes must agree on the validity of a transaction before it is added to the blockchain.
- Smart contracts: Self-executing contracts with the terms of the agreement being directly written into lines of code.


text: It was a pleasure meeting all of you, thanks for visiting!. Faber quality has involved many professionals, passionate and curious visitors during the three Italian exhibitions: CERSAIE, TECNARGILLA, and MARMOMAC!. Our response to your interest will always remain the same: maximum attention and passion in providing products and assistance of the highest quality, certain that your surfaces will continue to tell our successes!. During Cersaie (from 24th to 28th September) we had shown the best solutions for cleaning and maintenance of porcelain ceramic tiles.. In Tecnargilla (September, from 24th to 28th), we presented the most performing treatment for industrial line application for the ceramic industry.. During Marmomac (September, from 26th to 29th), our protective and polishing stone treatments was the protagonist of the event.

textbook:
Lesson Title: The Importance of Quality Control in Manufacturing

Introduction:
Quality control is an essential part of manufacturing processes. It ensures that products meet the required standards before they are released to the market. This lesson will explore the importance of quality control in manufacturing and its impact on businesses and consumers.

Section 1: What is Quality Control?

Quality control is the process of ensuring that products or services meet the required quality standards. It involves testing, inspection, and evaluation of products at different stages of production to ensure that they meet the desired quality and performance.

Section 2: Why is Quality Control Important?

Quality control is essential in manufacturing because it helps to prevent defects, reduce costs, and improve customer satisfaction. Here are some reasons why quality control is crucial:

1. Prevent Defects: Quality control helps to identify defects early in the production process. By doing so, manufacturers can make necessary adjustments to prevent the defects from reaching the market.

2. Reduce Costs: Defects can be costly to businesses. They may result in recalls, lawsuits, and damage to the company's reputation. Quality control helps to minimize these costs by identifying and fixing defects before they become a problem.

3. Improve Customer Satisfaction: Customers expect products to be of high quality. Quality control ensures that products meet these expectations, leading to higher customer satisfaction and loyalty.

Section 3: How does Quality Control Impact Businesses and Consumers?

Quality control has a significant impact on both businesses and consumers. Here's how:

1. Businesses: Quality control helps businesses to reduce costs, improve their reputation, and increase customer satisfaction. By ensuring that products meet the required quality standards, businesses can differentiate themselves from competitors and establish a strong brand identity.

2. Consumers: Quality control benefits consumers by ensuring that they receive products that are safe, reliable, and of high quality. When businesses prioritize quality control, consumers can trust that the products they purchase will meet their expectations and perform as intended.

Conclusion:

In conclusion, quality control is a critical component of manufacturing processes. It helps businesses to prevent defects, reduce costs, and improve customer satisfaction. By prioritizing quality control, businesses can establish a strong brand identity and differentiate themselves from competitors. As a consumer, you can trust that products that undergo quality control are safe, reliable, and of high quality.

Glossary:
- Quality Control: The process of ensuring that products or services meet the required quality standards.
- Defects: Flaws or imperfections in products that do not meet the required quality standards.
- Recalls: When a product is removed from the market due to safety concerns or other issues.

Self-Debate Discussion:

1. Why is it essential to prioritize quality control in manufacturing?
2. How does quality control impact businesses and consumers?
3. Can you think of any examples where quality control failed, and what were the consequences?


text:
Q:

WCF + SSL wsDualHttpBinding or netTcpBinding

I need to create a self-hosted WCF service.
I need secure duplex connection between client and server through Internet.
I read some documents of WCF and found that the netTcpBinding is suitable for intranet application, because the SSL is only point 2 point. If it is an internet application, the connection must not be point 2 point, am I correct? so SSL in transport security with netTcpBinding is not suitable?
so what combination should I use to create a secure duplex internet application?
thank you very much.

I have tried http://www.codeproject.com/KB/WCF/WCFWPFChat.aspx
this tutorial use netTcpBinding and endpoint localhost
I change the endpoint localhost to a name based url, forward a port in my router to my development PC, open the same port at Windows firewall.
The client program can chat with each cients program in different machines, BUT the callback connection will lost after one minute.
I also tried changing the binding to wsDualHttpBinding, the clients program can chat with each clients in the same machine and kept the callback connection in the reliableSession inactivityTimeout setting. However another client program in another machine cannot join the server, if I turn off Windows firewall on that machine, the client program can connect.
It seems that tcp binding can let the client program connecting to the server with Windows firewall turn on. but callback connection lost.
and the wsDualHttpBinding can keep the callback connections. but cannot connect to server if Windows firewall on.
Is there a way to kept the netTcpBinding callback connection as in the wsDualHttpBinding?

A:

It sounds like you have two issues- duplex connection and security.
If you truly need a duplex connection (eg, server-initiated callbacks), neither of these will work very well over the internet unless you have very fine control over the firewalls on both ends (the client still has to expose a publicly accessible HTTP endpoint for the server to call back). The best way would be to use the new relay services with .NET 4.0- this allows for a mimic'd server-initiated connection through firewalls.
EDIT: this is now called AppFabric, and is part of the Windows Azure infrastructure
On the security front, you can always use message security over the service bus, but I don't see a reason why transport security would be a problem either.

textbook:
Lesson: Secure Communication in WCF Services

Introduction:
In this lesson, we will learn about secure communication in WCF services. We will explore the different binding options available in WCF and their suitability for different scenarios. We will also discuss the importance of secure communication in web services and the different ways to achieve it.

Section 1: Introduction to Secure Communication in WCF Services

Topic 1: Importance of Secure Communication in Web Services
- Secure communication is essential in web services to protect sensitive data from unauthorized access, tampering, or disclosure.
- Secure communication ensures that only authorized users can access the data and that the data remains confidential, integrity, and availability.

Topic 2: Binding Options in WCF Services
- Binding options in WCF services determine how the service communicates with the client.
- There are four types of bindings in WCF services: BasicHttpBinding, WSHttpBinding, NetTcpBinding, and MSHttpBinding.
- BasicHttpBinding is used for simple HTTP services that do not require security.
- WSHttpBinding is used for secure web services that support SOAP messages with attachments.
- NetTcpBinding is used for reliable, ordered, and asynchronous messaging between services and clients over TCP.
- MSHttpBinding is used for Microsoft’s SOAP protocol and is suitable for web services that require advanced features such as reliable messaging and transactional behavior.

Section 2: Secure Communication with BasicHttpBinding

Topic 1: BasicHttpBinding and HTTPS
- BasicHttpBinding does not support secure communication over the internet.
- To achieve secure communication with BasicHttpBinding, you must use HTTPS.
- HTTPS uses SSL or TLS to encrypt the communication between the client and the server.

Topic 2: Configuring BasicHttpBinding with HTTPS
- To configure BasicHttpBinding with HTTPS, you must install an SSL certificate on the server.
- You must also configure the binding to use HTTPS by setting the <binding> element’s <https> configuration element.
- The <https> configuration element requires several attributes, including the certificate thumbprint, the certificate validation mode, and the maximum buffer pool size.

Section 3: Secure Communication with WSHttpBinding

Topic 1: WSHttpBinding and Security
- WSHttpBinding supports secure communication over the internet.
- It supports several security mechanisms, including SSL, SAML, and Kerberos.
- To enable security in WSHttpBinding, you must configure the binding to use one of these mechanisms.

Topic 2: Configuring WSHttpBinding with SSL
- To configure WSHttpBinding with SSL, you must install an SSL certificate on the server.
- You must also configure the binding to use SSL by setting the <binding> element’s <security> configuration element.
- The <security> configuration element requires several attributes, including the message protection requirements and the security mode.

Section 4: Secure Communication with NetTcpBinding

Topic 1: NetTcpBinding and Security
- NetTcpBinding does not support secure communication over the internet.
- It is designed for reliable, ordered, and asynchronous messaging between services and clients over TCP.
- It does not support security features such as SSL or SAML.

Section 5: Secure Communication with MSHttpBinding

Topic 1: MSHttpBinding and Security
- MSHttpBinding supports secure communication over the internet.
- It supports several security mechanisms, including SSL, SAML, and Kerberos.
- To enable security in MSHttpBinding, you must configure the binding to use one of these mechanisms.

Topic 2: Configuring MSHttpBinding with SSL
- To configure MSHttpBinding with SSL, you must install an SSL certificate on the server.
- You must also configure the binding to use SSL by setting the <binding> element’s <security> configuration element.
- The <security> configuration element requires several attributes, including the message protection requirements and the security mode.

Conclusion:
In this lesson, we learned about the different binding options in WCF services and their suitability for secure communication over the internet. We also explored the different ways to configure these bindings for secure communication using SSL, SAML, and Kerberos. Finally, we discussed the importance of secure communication in web services and the different ways to achieve it.

Glossary:
- Binding: A set of configuration settings that determine how a web service communicates with clients.
- SSL: Secure Sockets Layer, a protocol that provides secure communication over the internet.
- SAML: Security Assertion Markup Language, an XML-based protocol for exchanging authentication and authorization data between identity providers and service providers.
- Kerberos: A network authentication protocol that uses secret-key cryptography to provide secure authentication between two parties.

Self-Debating Discussion:
- Why is secure communication essential in web services?
- What are the different types of bindings in WCF services?
- How does BasicHttpBinding support secure communication over the internet?
- What is the difference between SSL and TLS?
- Why is NetTcpBinding not suitable for secure communication over the internet?


text:
TNF-R2 in tumor microenvironment as prognostic factor in epithelial ovarian cancer.
The aims of the study were to compare the levels of tumor necrosis factor alpha (TNF-α) and its soluble type I (sTNF-R1) and type II (sTNF-R2) receptors detected in intracystic liquid and serum from benign and malignant ovarian neoplasms and to relate them to prognostic factors in epithelial ovarian cancer. The patients were divided into benign ovarian neoplasms (n = 46) and malignant ovarian neoplasms (n = 17). The serum and intracystic samples were collected before and during surgery for ovarian cyst, respectively. The levels of TNF-α, sTNF-R1, and sTNF-R2 were measured using ELISA. Results were compared with the Mann-Whitney test. Concentration of sTNF-R2 in the intracystic samples collected from the malignant neoplasia was significantly higher than that of the benign neoplasias (p = 0.02). Higher intracystic levels of sTNF-R2 exhibited a significant association with tumor differentiation grades 2 and 3 (p = 0.0087). There was no statistical significance in relation to serum levels. Tumor microenvironment levels of sTNF-R2 may represent a factor of poor prognosis in epithelial ovarian cancer.

textbook:
Lesson: Understanding TNF-R2 in the Tumor Microenvironment

Introduction:
In this lesson, we will learn about the role of TNF-R2 in the tumor microenvironment and its potential as a prognostic factor in epithelial ovarian cancer. We will explore the relationship between TNF-R2 levels and tumor differentiation grades, and discuss the implications of these findings for cancer treatment and diagnosis.

Section 1: Understanding the Tumor Microenvironment

The tumor microenvironment refers to the cellular environment surrounding a tumor, which includes immune cells, blood vessels, and other factors that can influence tumor growth and progression. The tumor microenvironment plays a crucial role in cancer development and progression, and understanding its components can help researchers develop new therapies and diagnostic tools.

Section 2: TNF-R2 and its Role in the Tumor Microenvironment

TNF-R2 is a protein that binds to a signaling molecule called tumor necrosis factor-alpha (TNF-α). TNF-α is involved in various biological processes, including inflammation, immune response, and cell survival. In the tumor microenvironment, TNF-α can promote tumor growth and resistance to chemotherapy.

Studies have shown that TNF-R2 levels are higher in the tumor microenvironment of epithelial ovarian cancer compared to benign ovarian neoplasms. This suggests that TNF-R2 may play a role in the progression of this cancer.

Section 3: TNF-R2 as a Prognostic Factor in Epithelial Ovarian Cancer

Researchers have found that higher levels of TNF-R2 in the intracystic samples collected from malignant ovarian neoplasms are associated with poor prognosis. This suggests that TNF-R2 may be a useful biomarker for predicting the course of epithelial ovarian cancer.

Section 4: Implications for Cancer Treatment and Diagnosis

Understanding the role of TNF-R2 in the tumor microenvironment and its potential as a prognostic factor in epithelial ovarian cancer has several implications for cancer treatment and diagnosis. For example, TNF-R2 levels could be used to identify patients who are more likely to develop aggressive forms of cancer, allowing for earlier intervention and treatment. Additionally, targeting TNF-R2 with therapies that block its function may help slow down or prevent the progression of epithelial ovarian cancer.

Conclusion:
In this lesson, we have learned about the tumor microenvironment and its components, including TNF-R2. We have explored the role of TNF-R2 in the tumor microenvironment and its potential as a prognostic factor in epithelial ovarian cancer. Finally, we have discussed the implications of these findings for cancer treatment and diagnosis. By understanding the complex interactions between TNF-R2 and the tumor microenvironment, researchers can develop new therapies and diagnostic tools to improve patient outcomes.


text: You are here:. In this article, Oxfam Novib presents part of the results of the implementation of the Measuring Milestones Initiative, which aimed to make visible deep changes related to gender equality in the structure and culture of development organisations and their programmes in the communities where they work. Some conclusions from 123 Most Significant Change stories are that continuous and consistent work on gender mainstreaming does induce transformational change in favour of gender justice. The analysis of the stories made clear that transformation is about small steps forward. It became also clear that change in gender relations can start in different ways - there is not ‘one way to go’ in this complex matter. To measure these changes various tools should be used, as they are complementary and generate different.

textbook:
Lesson: Measuring Gender Equality in Development Organizations

## Section 1: Introduction to Measuring Gender Equality

Gender equality is a fundamental human right and an essential component of sustainable development. However, achieving gender equality requires more than just legislation and policies; it requires a systematic approach that involves measuring progress towards this goal. In this lesson, we will explore how development organizations can measure gender equality in their programs and initiatives.

## Section 2: Understanding Gender Mainstreaming

Gender mainstreaming is the process of assessing the implications for women and men of any planned action, including legislation, policies, or programs, and taking account of these implications in the design and implementation of such action. It involves integrating gender perspectives into all areas of development work, including programming, monitoring and evaluation, and resource allocation.

To implement gender mainstreaming effectively, development organizations need to collect data on gender equality outcomes and track progress over time. This data can be used to identify gaps and areas where interventions are needed.

## Section 3: Tools for Measuring Gender Equality

There are several tools that development organizations can use to measure gender equality, including:

1. Gender Analysis: This tool involves analyzing the differences between women and men's experiences, opportunities, and constraints in a particular context. It helps identify the root causes of gender inequality and informs the design of targeted interventions.

2. Gender-related Indicators: These are quantitative measures that help track progress towards gender equality goals. Examples include the proportion of women in leadership positions, the gender pay gap, and the prevalence of violence against women.

3. Participatory Methods: These involve engaging women and men in the collection and analysis of data on their lives and experiences. Participatory methods can provide valuable insights into the impact of development programs on gender relations and identify areas where further action is needed.

## Section 4: Conclusion

Measuring gender equality is essential for achieving gender justice in development programs. By collecting and analyzing data on gender outcomes, development organizations can identify gaps and areas where interventions are needed. Gender mainstreaming involves integrating gender perspectives into all areas of development work, including programming, monitoring and evaluation, and resource allocation. The tools discussed in this lesson can be used to measure gender equality and track progress towards gender justice.

Glossary:
- Gender Analysis: A tool for analyzing the differences between women and men's experiences, opportunities, and constraints in a particular context.
- Gender-related Indicators: Quantitative measures that help track progress towards gender equality goals.
- Participatory Methods: Engaging women and men in the collection and analysis of data on their lives and experiences.


text: Oh, man. I need to work. A lot.. Last year it took me 28 days exactly to produce an entry worthy of an honorable mention, from shrink wrap to delivery. This year I am trying for six categories with about twice that time left to paint. The scary part is that I actually want to do a seventh category, if I have time. Where am I going to get time?!. Actually, it's not as bad as I'm making it sound. Last year was a huge conversion project, and I spent a lot of the time trying out different versions of the conversion, as well as playing with different paint additives for the first time. This year it's mostly just single model, so precision is the goal.. Nevertheless, I gotta get working.. Blackbarrow Chronicles, Episode 3 -The Wayside Drinkers Club - The Return of Green Magic Green Magic is long standing theme in my games , and especially on this particular piece of terrain using ( my Hirst Arts “fie.... 14 hours ago

textbook:
Lesson: The Importance of Time Management
Introduction:
Time management is an essential skill that can help us achieve our goals and be more productive in our daily lives. In this lesson, we will learn about the importance of time management and how to apply it in various scenarios.
Core Value:
The core value of time management is the ability to prioritize tasks and allocate time effectively to achieve desired outcomes.
Section 1: Understanding the Concept of Time Management
Topic 1: What is Time Management?
Time management is the process of planning and controlling how much time we spend on specific activities to achieve our goals. It involves setting priorities, creating schedules, and managing our time effectively to avoid wasting time on unimportant tasks.
Topic 2: Why is Time Management Important?
Time management is essential because it helps us achieve our goals efficiently and effectively. By prioritizing tasks and allocating time wisely, we can accomplish more in less time, leaving us with more free time to relax and pursue other interests.
Section 2: Applying Time Management Techniques
Topic 1: Setting Priorities
Setting priorities is the first step in time management. We need to identify the most important tasks and allocate time to them first. We can use a to-do list or a planner to keep track of our tasks and their deadlines.
Topic 2: Creating Schedules
Once we have identified our priorities, we need to create a schedule that allocates time to each task. We should avoid procrastination and start working on our tasks as soon as possible. We can use a calendar or a planner to schedule our tasks and set reminders for deadlines.
Topic 3: Managing Interruptions
Interruptions can be a significant source of time wastage. We need to learn how to manage interruptions effectively by turning off notifications, closing unnecessary tabs, and avoiding distractions.
Section 3: Practical Examples
Topic 1: Using Time Management in School
In school, time management is crucial for completing assignments, studying for exams, and participating in extracurricular activities. Students can use time management techniques to prioritize tasks, create schedules, and avoid procrastination.
Topic 2: Using Time Management at Work
At work, time management is essential for completing tasks, meeting deadlines, and achieving goals. Employees can use time management techniques to prioritize tasks, create schedules, and avoid multitasking.
Conclusion:
Time management is a valuable skill that can help us achieve our goals and be more productive in our daily lives. By applying time management techniques, we can prioritize tasks, create schedules, and avoid wasting time on unimportant tasks. By mastering time management, we can achieve more in less time, leaving us with more free time to pursue other interests.


text: ‘Beautiful Japanese Garden Garden Statues Accents Beautiful Japanese Garden Pictures’. beautiful japanese garden garden statues accents beautiful japanese garden pictures.. beautiful japanese home gardens japanology plus say garden in samurai district,beautiful japanese garden wallpapers most gardens in tokyo stock photo small designs,is back on the charts with world gardens most beautiful japanese in tokyo small,most beautiful japanese gardens in tokyo best ideas landscape design garden music zen wallpapers,most beautiful japanese gardens in tokyo garden wallpapers pictures,say beautiful garden japanese gardens from the heaven music zen wallpapers,say beautiful garden japanese gardens pond homes japanology plus,beautiful garden and pond stock images search say japanese music zen gardens japanology plus,beautiful japanese gardens wallpapers music zen garden japanology plus most in the world museum,beautiful japanese music zen garden stock photo nature free pictures most gardens in tokyo.

textbook:
Lesson Title: Introduction to Beautiful Japanese Gardens

Introduction:
In this lesson, we will explore the beauty and elegance of Japanese gardens. We will learn about their history, design principles, and the various types of gardens found in Japan. By the end of this lesson, you will be able to appreciate the art of Japanese gardening and understand its significance in Japanese culture.

Section 1: History of Japanese Gardens

Question: When were Japanese gardens first created?
Answer: Japanese gardens have a long history dating back to the 6th century when they were first created by Japanese monks who had studied in China.

Question: What was the purpose of Japanese gardens in ancient times?
Answer: In ancient times, Japanese gardens were primarily used for religious purposes. They were designed to create a sacred space where people could come to pray and meditate.

Question: How have Japanese gardens evolved over time?
Answer: Over time, Japanese gardens have evolved to reflect the changing seasons and the natural beauty of Japan. They have also become more accessible to the general public, with many gardens being open to visitors.

Section 2: Design Principles of Japanese Gardens

Question: What are some design principles used in Japanese gardens?
Answer: Some design principles used in Japanese gardens include simplicity, asymmetry, and the use of natural materials. These principles help to create a sense of harmony and balance within the garden.

Question: What is the importance of rocks in Japanese gardens?
Answer: Rocks play an important role in Japanese gardens as they represent the stability and strength of nature. They are often used to create a focal point within the garden and to represent the mountains that surround Japan.

Section 3: Types of Japanese Gardens

Question: What are some common types of Japanese gardens?
Answer: Some common types of Japanese gardens include tea gardens, stroll gardens, and rock gardens. Each type of garden has its own unique characteristics and design elements.

Question: What is a tea garden?
Answer: A tea garden is a type of Japanese garden that is designed to be used for tea ceremonies. These gardens typically feature a teahouse and a small pond or stream.

Conclusion:
In conclusion, Japanese gardens are a beautiful and significant part of Japanese culture. They reflect the beauty and elegance of nature and provide a peaceful escape from the hustle and bustle of daily life. By understanding the history, design principles, and types of Japanese gardens, we can appreciate their beauty and significance even more.


text:
Medical/health care providers (“care providers”) are increasingly being put under pressure to improve their outcomes and decrease costs. Outpatient services are one way to decrease costs by not requiring patients to utilize hospitals. Whether patients are discharged from hospitals or outpatient services, means of reducing re-admissions are desirable to reduce costs, and in fact, government agencies and insurance companies are putting pressure on care providers to avoid costly re-admissions. Finally, patient home care is increasingly being utilized to avoid nursing home costs and risks (such as risk of transmitting communicable infections).
To support all of these services in a reduced-cost matter, such care providers are increasingly bringing services to the homes of the patients. Follow up care is utilized to help prevent costly readmissions, and to ensure that the patients are complying with doctor ordered drug and therapy regimes. Furthermore, nurses, skilled therapists, and other service providers are visiting the homes of the patients to provide such services. Such providers of services can often thereby visit the homes of patients to provide their services.
However, a problem exists that currently, it is difficult to ensure that these providers are performing the services for which they are being paid. Visits are typically self-reported by the provider employee, and thus can easily be improperly reported or even fraudulently misrepresented. Currently, provider activities done in patient homes use paper systems utilizing a “time sheet” that is filled out manually by the provider employee and then signed by both the Provider employee and the patient (client) and then forwarded to a third party for processing. However, such time sheets are basically validated by an “honor system” that accepts the word of the provider employee and client. The client does not typically work as an effective check or verification on this process, as there is rarely much motivation on the client to check the actual time entries of the provider employee, because the client is typically not paying directly for the services and in some cases may not be mentally capable of checking the employee's entries.
Hence, payer organizations desire proof and more effective verifications that such provider employees are actually providing the services for which the provider is billing the payer. Hence, a means of better ensuring that the services being billed have actually been performed is desirable.

textbook:
Lesson: Home Health Care Services
Introduction:
Home health care services are becoming increasingly popular among medical/health care providers as they provide a cost-effective way to deliver quality care to patients in the comfort of their own homes. In this lesson, we will explore the benefits of home health care services, the challenges associated with providing care in a home setting, and the role of technology in improving the efficiency and effectiveness of home health care.
Section 1: Benefits of Home Health Care Services
Home health care services offer several advantages over traditional hospital or nursing home care. These include:
- Cost savings: Home health care services are typically less expensive than hospital stays or nursing home care.
- Convenience: Patients can receive care in the comfort of their own homes, which can be more convenient for both the patient and their family members.
- Personalized care: Home health care services allow for more personalized care plans that are tailored to the specific needs of each patient.
- Improved outcomes: Studies have shown that home health care services can lead to better health outcomes for patients, including improved mobility, reduced hospital readmissions, and increased survival rates.
Section 2: Challenges of Providing Care in a Home Setting
While home health care services offer many benefits, there are also some challenges associated with providing care in a home setting. These challenges include:
- Limited access to equipment and resources: Home health care providers may not have access to the same equipment and resources that are available in a hospital or nursing home setting.
- Limited supervision: Home health care providers may not have the same level of supervision and support that they would have in a hospital or nursing home setting.
- Patient compliance: Patients may be less likely to follow their care plan when they are receiving care in their own homes.
Section 3: Role of Technology in Home Health Care Services
Technology plays an increasingly important role in home health care services. Some examples of how technology can improve the efficiency and effectiveness of home health care services include:
- Telehealth: Telehealth allows health care providers to remotely monitor patients and provide care via video conferencing or other remote communication tools.
- Mobile apps: Mobile apps can help patients track their medication schedules, monitor their symptoms, and communicate with their health care providers.
- Wearables: Wearable devices such as fitness trackers and smartwatches can help patients monitor their physical activity and vital signs.
Conclusion:
Home health care services offer several benefits over traditional hospital or nursing home care, including cost savings, convenience, personalized care, and improved outcomes. However, there are also some challenges associated with providing care in a home setting. Technology can play an important role in overcoming these challenges and improving the efficiency and effectiveness of home health care services. By understanding the benefits, challenges, and role of technology in home health care services, patients and health care providers can work together to ensure that patients receive the highest quality care possible.


text: No Results. (ISSN: 0888-0395). Show only:. Full-text on Medscape. October 02, 2008. September 25, 2008. July 22, 2008. July 18, 2008. June 17, 2008. June 10, 2008. June 03, 2008. May 27, 2008. May 20, 2008. May 14, 2008. March 31, 2008. March 19, 2008. February 20, 2008. February 13, 2008. February 06, 2008. October 08, 2007. October 02, 2007. September 26, 2007. July 12, 2007. July 05, 2007. Mission Statement:. The. Journal of Neuroscience Nursing. , the journal of the American Association of Neuroscience Nurses, publishes original manuscripts pertinent to neurosurgical/neurological nursing standards, education and practice, related paramedical fields, and clinical neurosurgical/neurological nursing research.


text: PAST IN TIME In March on the EBC network LITTLE HOOD OF ALL COLORS New TV series based on the book by Chico Buarque and Ziraldo. WORMS 2 - The spy who forgets too much Feature Films Short Films TV Series Advertising Animaking is an animation producer that values creativity and innovation. Our mission is to produce enchanting and memorable content. Throughout our 16 years, we have developed proprietary methodologies and technologies that include industrial prototyping, motion control and real-time animation renderers, in order to materialize this vision. As a result, among other projects, we produced Brazil’s first stop motion feature, which was released in theaters in more than 30 countries, including the US and France. Get more

textbook:
Lesson: The Importance of Time Management

Introduction:
Time management is a crucial skill that helps individuals accomplish their tasks effectively and efficiently. It involves planning and organizing activities to make the most of the available time. In this lesson, we will explore the importance of time management and learn strategies to improve our productivity.

Section 1: Understanding Time Management

Topic 1: What is Time Management?
Time management is the process of organizing and planning how to divide your time between different activities. It helps you work smarter, not harder, by ensuring that you complete important tasks without wasting time on unnecessary activities.

Topic 2: Why is Time Management Important?
Time management is essential because it allows us to achieve our goals and be more productive. When we manage our time well, we can focus on completing tasks that matter, avoid procrastination, and reduce stress levels. By prioritizing tasks and setting achievable goals, we can also improve our overall quality of life.

Section 2: Strategies for Effective Time Management

Topic 1: Prioritize Tasks
Prioritizing tasks involves identifying the most important tasks and completing them first. This strategy helps ensure that you focus on what matters most and avoid wasting time on less significant activities. To prioritize tasks effectively, consider the following steps:

1. List all your tasks and assign them a level of importance.
2. Rank tasks based on their priority level.
3. Complete the highest-priority tasks first.

Topic 2: Use a Calendar and To-Do List
A calendar and to-do list are essential tools for effective time management. A calendar helps you schedule your tasks and appointments, while a to-do list allows you to track your daily tasks and ensure that you complete them. To use these tools effectively, follow these steps:

1. Plan your weekly tasks and schedule them on your calendar.
2. Update your to-do list daily with tasks that need to be completed.
3. Cross off completed tasks on your to-do list and update your calendar as needed.

Topic 3: Avoid Distractions
Distractions are anything that takes your attention away from your tasks. They can be social media, television, or even your phone. To minimize distractions, try the following strategies:

1. Turn off notifications on your phone and computer.
2. Set aside specific times for checking social media or email.
3. Work in a quiet and peaceful environment.

Section 3: Applying Time Management Skills

Topic 1: Practice Time Management at Home
You can practice time management skills at home by creating a routine that includes designated times for tasks such as homework, chores, and playtime. Encourage your child to prioritize tasks and avoid distractions.

Topic 2: Time Management at School
At school, time management involves planning and organizing study time effectively. Encourage your child to use a planner or calendar to schedule their study sessions and break them into manageable chunks.

Conclusion:
Time management is a vital skill that helps individuals be more productive and achieve their goals. By prioritizing tasks, using a calendar and to-do list, and avoiding distractions, we can improve our time management skills and lead more fulfilling lives.


text: September 15 2014 Latest news:. Madeleine Burton. Thursday, May 22, 2014. 10:48 AM. Ten small books on trees for small people have been published by local author Kate Bretherton.. The author of The Remarkable Trees of St Albans took on board comments from readers that they wished they had learned to recognise trees as children and created a series of Hello Trees books geared at children.. Each book is given a name and they range from Arthur and Annie Ash through Crabby Crabapple to Olly Oak.. They focus on common trees which are easy to spot while out and about.. Kate is hosting a workshop for youngsters at 11am and 3pm this Saturday (24) at Waterstones in St Albans at which she will have magnifying glasses, twigs, flowers and fruits for the children to scrutinise and look up.. {{fields.description}}. ADVERTISEMENT

textbook:
Lesson Title: Identifying Trees with Kate Bretherton

Introduction:
In this lesson, we will learn about identifying trees with Kate Bretherton, the author of "Hello Trees" books. We will explore the different types of trees, their characteristics, and how to identify them. This lesson is suitable for primary through high school students who want to learn more about nature and the environment.

Section 1: Understanding Trees

**Topic 1: What are trees?**
- Definition: A tree is a tall plant with a single stem or trunk, branches, and leaves.
- Question: How do trees grow?
- Answer: Trees grow by absorbing water and nutrients from the soil, and by photosynthesis, which converts sunlight into energy.

**Topic 2: Types of Trees**
- Definition: There are many types of trees, such as deciduous, coniferous, and broadleaf.
- Question: What are some examples of deciduous trees?
- Answer: Some examples of deciduous trees include oak, maple, and birch.
- Question: What are some examples of coniferous trees?
- Answer: Some examples of coniferous trees include pine, spruce, and fir.

Section 2: Identifying Trees

**Topic 3: Characteristics of Trees**
- Definition: Trees have different characteristics that can help us identify them. These include their shape, bark, leaves, and flowers.
- Question: What is the shape of a tree?
- Answer: The shape of a tree depends on its type. For example, deciduous trees tend to have a round shape, while coniferous trees have a more conical shape.
- Question: What is bark?
- Answer: Bark is the outer covering of a tree's trunk and branches. It protects the tree from damage and helps it to grow.
- Question: What are leaves?
- Answer: Leaves are the green parts of a tree that absorb sunlight and convert it into energy through photosynthesis.
- Question: What are flowers?
- Answer: Flowers are the reproductive organs of trees, and they produce seeds that grow into new trees.

**Topic 4: Identifying Trees**
- Definition: We can identify trees by looking at their characteristics, such as their shape, bark, leaves, and flowers.
- Question: How do we identify trees?
- Answer: We can identify trees by comparing their characteristics to those of other trees. For example, if we see a tree with needle-like leaves and a conical shape, we can identify it as a coniferous tree.
- Question: How do we use magnifying glasses to identify trees?
- Answer: We can use magnifying glasses to examine the details of a tree's bark, leaves, and flowers. This can help us identify the type of tree we are looking at.

Section 3: Practical Examples

**Topic 5: Identifying Trees in Real Life**
- Definition: We can identify trees in real life by looking for their characteristics.
- Question: How do we identify trees in our neighborhood?
- Answer: We can identify trees in our neighborhood by looking for their shape, bark, leaves, and flowers. We can also compare these characteristics to those of other trees to help us identify them.
- Question: How do we identify trees in a forest?
- Answer: In a forest, we can identify trees by looking for their shape, bark, leaves, and flowers. We can also listen for the sounds of birds and animals, as they can indicate the presence of certain types of trees.

Conclusion:
In this lesson, we have learned about the different types of trees, their characteristics, and how to identify them. We have also explored practical examples of identifying trees in real life. By understanding the importance of trees and their role in our environment, we can appreciate and protect them.

Glossary:
- Deciduous: A tree that loses its leaves in the fall.
- Coniferous: A tree that keeps its needles year-round.
- Broadleaf: A tree with wide, flat leaves.
- Trunk: The main stem of a tree.
- Branch: A part of a tree that grows out from the trunk.
- Leaf: The green part of a tree that absorbs sunlight and converts it into energy.
- Flower: The reproductive organ of a tree.
- Bark: The outer covering of a tree's trunk and branches.


text: Hi trying to find his memory back. Amy thought that her dad wants to marry another women since she spy on him, but is it true that her dad is marrying another person or is he helping someone? Try to read the book so you know what happens! The book is so mystery and when you start reading this book you don’t want to stop reading it because you are so curious about what happens next. Have a nice day! 🙂

textbook:
Lesson: Critical Thinking and Problem Solving
Introduction:
Critical thinking and problem-solving are essential skills that help us make informed decisions and solve complex problems. In this lesson, we will learn how to apply these skills to real-world scenarios.
Section 1: Introduction to Critical Thinking and Problem Solving
Topic 1: What is critical thinking and problem-solving?
Critical thinking is the process of evaluating information to determine its accuracy and relevance. Problem-solving involves identifying a problem, analyzing it, and finding a solution. Both skills are essential for making informed decisions and solving complex problems.
Topic 2: Why are critical thinking and problem-solving important?
Critical thinking and problem-solving are important because they help us make informed decisions and solve complex problems. These skills are essential for success in school, work, and life in general.
Section 2: Applying Critical Thinking and Problem Solving
Topic 1: How do you apply critical thinking and problem-solving skills?
To apply critical thinking and problem-solving skills, you need to follow a structured approach. This involves identifying the problem, gathering information, analyzing the information, generating possible solutions, evaluating the solutions, and implementing the best solution.
Topic 2: Real-world examples of critical thinking and problem-solving
Critical thinking and problem-solving skills can be applied to a wide range of real-world scenarios. For example, a business owner may use these skills to identify a problem with their supply chain and find a solution that minimizes disruption to their operations. A student may use these skills to evaluate the accuracy of a source of information and use it to write an essay.
Section 3: Practice Problems
Topic 1: Identifying the problem
Read the following passage and identify the problem that Amy is facing.
"Hi trying to find his memory back. Amy thought that her dad wants to marry another women since she spy on him, but is it true that her dad is marrying another person or is he helping someone? Try to read the book so you know what happens next. The book is so mystery and when you start reading this book you don’t want to stop reading it because you are so curious about what happens next."
Problem: Amy is trying to find her father's memory and is unsure if he wants to marry another woman or is helping someone else.
Topic 2: Generating possible solutions
Think of at least three possible solutions to Amy's problem.
Solution 1: Amy could talk to her father and ask him directly about his intentions.
Solution 2: Amy could try to find out more information about the situation by talking to other people who may know more.
Solution 3: Amy could try to remember more about her father's behavior and past actions to see if there are any clues that could help her understand his intentions.
Conclusion:
In this lesson, we learned about critical thinking and problem-solving and how these skills can be applied to real-world scenarios. We also practiced applying these skills to a problem and generated possible solutions. By developing these skills, we can make informed decisions and solve complex problems.
Glossary:
Critical thinking: The process of evaluating information to determine its accuracy and relevance.
Problem-solving: The process of identifying a problem, analyzing it, and finding a solution.
Structured approach: A step-by-step process for solving problems.


text: Project Summary NIH SBIR Phase-II, Jan 5, 2017 Application Title: ?A disposable assay for the monitoring of heart failure at the point-of-care? Accel Diagnostics, LLC Contact PI: Alberto Gandini, Ph.D., MBA The objective of this proposed SBIR Phase II is to complete the development and optimization of the pScreen-BNP? platform for the monitoring of Heart Failure, HF, in home patients. The proposed activities include integration of a smart phone app, scale up manufacturing capability that adhere to the FDA Quality Control guidelines, reduce production cost, and complete a clinical validation study in collaboration with The University of California San Francisco. The pScreen-BNP has several unique features. It is fully disposable (single use) and does not requires bench-top or hand-held devices, hence it is easy to use and very affordable; it is also a quantitative and sensitive assay, hence it provides an accurate and precise quantification of the level of Brain Natriuretic Peptide (BNP) in HF patients' blood. BNP is a cardiac biomarker elaborated by heart tissue when stressed due to the onset of heart failure. It is widely known for its specificity and sensitivity in the diagnosis of HF. Heart Failure remains a leading cause of death and disability in elderly Americans, and places a significant burden on the healthcare systems with a cost exceeding $40 billion/year. Early diagnosis is a critical necessity to achieve meaningful change in outcome. pScreen-BNP? marks in this respect, a paradigm shift in HF management. It allows, for the first time, HF patients to frequently monitor their level of heart distress outside of the clinical setting, e.g. in the comfort of their homes, similar to the more familiar glucose test. Our solution would enables patients and their physicians to respond before physical symptoms occur, preventing otherwise frequent life threatening events and costly re- hospitalizations. pScreen-BNP? is based on a patent-protected technology initially developed at Carnegie Mellon University, and licensed exclusively Worldwide to Accel Diagnostics.

textbook:
Lesson Title: Introduction to Disposable Assays

Lesson Overview: In this lesson, we will learn about disposable assays and their applications in monitoring heart failure at the point-of-care. We will explore the unique features of pScreen-BNP, a disposable assay for measuring BNP levels, and discuss its potential benefits over traditional methods.

Section 1: What are Disposable Assays?

Disposable assays are diagnostic tests that can be used only once and then discarded. They are designed to be used at the point-of-care, meaning that they can be performed in a doctor's office, clinic, or other healthcare settings without the need for specialized equipment or trained personnel. Disposable assays are becoming increasingly popular due to their convenience, affordability, and accuracy.

Section 2: The pScreen-BNP Assay

The pScreen-BNP assay is a disposable assay developed by Accel Diagnostics, LLC. It is designed to measure the level of BNP (Brain Natriuretic Peptide) in a patient's blood. BNP is a hormone released by the heart in response to stress, such as heart failure. By measuring BNP levels, doctors can assess the severity of heart failure and determine the best course of treatment for their patients.

The pScreen-BNP assay has several unique features that make it advantageous over traditional methods:

- Fully disposable: The pScreen-BNP assay is single-use, which means that it can be used once and then discarded. This eliminates the need for expensive equipment or specialized training, making it more affordable and accessible.
- Quantitative and sensitive: The pScreen-BNP assay is highly accurate and precise, allowing for precise measurements of BNP levels.
- Easy to use: The pScreen-BNP assay is designed to be used at the point-of-care, meaning that it can be performed in a doctor's office or clinic without the need for specialized equipment or trained personnel.

Section 3: Applications of Disposable Assays in Monitoring Heart Failure

Disposable assays, like the pScreen-BNP assay, have several applications in monitoring heart failure:

- Early detection: Disposable assays can be used to detect the presence of BNP in a patient's blood, which can help doctors diagnose heart failure early on.
- Monitoring progression: Disposable assays can be used to monitor the progression of heart failure by measuring changes in BNP levels over time.
- Guiding treatment: Disposable assays can be used to guide treatment decisions by providing doctors with information about a patient's BNP levels, which can help determine the most effective course of action.

Section 4: Conclusion

In conclusion, disposable assays like the pScreen-BNP assay offer several advantages over traditional methods of monitoring heart failure. Their ease of use, affordability, and accuracy make them an attractive option for healthcare providers looking to improve patient care. By understanding the unique features of disposable assays and their potential benefits, we can better appreciate their role in modern medicine.


text: The company, knows our history. More of 80 years of service to the hotel. Group La Raza is one of the main Andalusian companies specializing in catering and hotel services.. Important recognitions support the experience and professionalism of the company, as concessions to the Group La Raza Medal of the City of Seville and Certification Q for Quality Tourism their establishments Restaurante La Raza and La Hosteria del Prado, and La Raza Catering (Health Registration No.: 26.0008557/HE), that since 2008 It is one of the few catering Andalusia that has certified with the Q for Quality Tourism.

textbook:
Lesson: Introduction to Business Management

**Objective:** To introduce students to the basics of business management and its importance in the success of a company.

**Section 1: Theoretical Concepts**

- Business management is the process of planning, organizing, leading, and controlling the resources of a company to achieve its goals.
- It involves making decisions about the use of resources, such as finances, people, and technology, to ensure that the company operates efficiently and effectively.
- Business management is essential for the growth and development of a company, as it helps to identify opportunities, solve problems, and make informed decisions.

**Section 2: Practical Examples**

- Group La Raza is a company that specializes in catering and hotel services. It has been in operation for over 80 years and has received several recognitions for its experience and professionalism, including concessions to the Medal of the City of Seville and Certification Q for Quality Tourism for its establishments Restaurante La Raza and La Hosteria del Prado, and La Raza Catering.
- By applying effective business management practices, Group La Raza has been able to grow and develop its brand while maintaining a high level of quality and service.
- This example shows how important business management is in ensuring the success of a company.

**Section 3: Self-Debating Discussions**

- What are some of the challenges that companies face when it comes to business management?
- How can companies ensure that they are using their resources effectively and efficiently?
- What role does business management play in the growth and development of a company?

**Glossary**

- Business management: The process of planning, organizing, leading, and controlling the resources of a company to achieve its goals.
- Resources: Finances, people, and technology used by a company to operate efficiently and effectively.
- Goals: Objectives that a company aims to achieve through its business operations.
- Efficiency: The ability to produce desired results with minimal waste or unnecessary effort.
- Effectiveness: The ability to achieve desired results in a timely and efficient manner.

**Conclusion**

Effective business management is crucial for the success of any company. By understanding the principles of business management and applying them to real-world scenarios, students can gain valuable insights into how companies operate and how they can improve their own business practices. Through this lesson, students will learn about the importance of business management, its practical applications, and how to think critically about the challenges facing companies today.


text:
Nottingham Business School

Role

Dr Sheilagh Resnick is a Senior Lecturer in the Division of Marketing. She runs a final year undergraduate module, Improving the Customer Experience, in addition to teaching on Masters courses and supervising PhD and DBA students.

Career overview

Prior to joining Nottingham Business School, Sheilagh worked for one of the UK’s largest retailers, Alliance Boots, in a series of retail marketing and senior management positions including that of Buying Controller, Director of Public Relations and Director of Customer Service.

Research areas

Sheilagh is an active researcher and her research interests lie in attributes of marketing within retail and in particular within SMEs. She has publications in Studies in Higher Education (ABS 3*) the International Journal of Retail and Distribution Management, (ABS 2*), The Services Industries Journal (ABS 2*) amongst others. She was a co-investigator on the ESRC funded Retail Navigator Initiative (2012-2013) and has been funded by the Academy of Marketing.

External activity

Funded by the Academy of Marketing

Currently part of a team from Nottingham Business School funded by the ESRC (Economic & Social Research Council) to investigate the potential for research in the UK retail sector and encourage greater collaboration and knowledge exchange.

textbook:
Title: Introduction to Marketing

**Overview:** Marketing is the process of identifying, understanding, and satisfying customer needs and wants. It involves creating value for customers and building long-term relationships with them. This lesson will introduce you to the basics of marketing, including its definition, key components, and strategies.

**Section 1: What is Marketing?**

Marketing is the activity and process of creating, communicating, delivering, and exchanging offerings that have value for customers, clients, partners, and society at large. It involves identifying the needs and wants of potential customers and delivering products or services that meet those needs and desires.

**Section 2: Key Components of Marketing**

There are four key components of marketing:

1. Product: This refers to the tangible product or intangible service that a business offers to its customers.
2. Price: This refers to the amount of money that customers must pay for the product or service.
3. Place: This refers to the location where the product or service is sold or delivered.
4. Promotion: This refers to the marketing communication used to create awareness and interest in the product or service.

**Section 3: Marketing Strategies**

Marketing strategies involve creating a plan to reach potential customers and convince them to buy your product or service. Some common marketing strategies include:

1. Advertising: This involves creating ads to promote your product or service.
2. Sales promotions: This involves offering short-term incentives such as discounts or coupons to encourage people to buy your product or service.
3. Public relations: This involves building a positive reputation for your brand through media coverage and other public relations efforts.
4. Personal selling: This involves meeting with potential customers one-on-one to sell your product or service.

**Section 4: Conclusion**

Marketing is an essential part of any business. By understanding the needs and wants of potential customers and delivering products or services that meet those needs and desires, businesses can create long-lasting relationships with their customers. By implementing effective marketing strategies, businesses can increase their visibility, attract more customers, and ultimately increase their sales and profits.


text: Description. 3.5in x 2in (88.9mm x 50.8mm) Notice Disabled Driver Sticker. Notice Disabled Driver Sticker Description:. This sticker is 3.5 inches wide by 2 inches tall when applied. The word, NOTICE, is printed at the top of the sticker in white letters on a blue rectangle; under this the words, DISABLED DRIVER, are printed in black letters on a white background. A blue and white handicap symbol appears on the left side of the main body of text, and a black border is printed on all edges of the sticker. The pink line in the image shows where the sticker is cut. This quality-made product is an effective way to promote safety while traveling.. Premium Quality Stickers:. StickerTalk stickers are made to the highest standards. Your Notice Disabled Driver Sticker unless we know it is the best we can make.. Reviews. There are no reviews yet.

textbook:
Lesson: Understanding the Importance of Accessibility Stickers

Introduction:
Accessibility stickers are essential tools used to promote safety and accessibility for people with disabilities. In this lesson, we will learn about the importance of accessibility stickers and how they help individuals with disabilities.

Section 1: Theoretical Concepts

**What is an accessibility sticker?**
An accessibility sticker is a label that indicates a parking space or facility is designated for use by individuals with disabilities. These stickers are usually placed on vehicles or in public spaces to provide access to individuals who may require special assistance.

**Why are accessibility stickers important?**
Accessibility stickers are important because they help individuals with disabilities identify parking spaces or facilities that are accessible to them. These stickers provide an easy way for individuals with disabilities to find accessible parking or facilities, making their lives easier and more convenient.

Section 2: Practical Examples

**Example 1**
Let's say you are driving in a city and see a car with an accessibility sticker parked in a handicap spot. This means that the driver of the car most likely has a disability and needs the extra space or accessibility features provided by the handicap spot. It is important not to park in this spot if you do not have an accessibility sticker yourself, as it could prevent someone with a disability from accessing the space they need.

**Example 2**
Imagine you are visiting a new city and need to find an accessible restroom. Look for a sign with an accessibility sticker indicating which restrooms are wheelchair accessible. This will help you find a restroom that meets your needs and ensures you can use the facility comfortably.

Section 3: Real-World Scenarios

**Scenario 1**
You are driving in a city and see a car without an accessibility sticker parked in a handicap spot. What should you do?
a) Honk your horn and yell at the driver
b) Call the police to report the illegally parked car
c) Find another parking spot and leave a note on the windshield
d) All of the above

**Answer**
 c) Find another parking spot and leave a note on the windshield. While it may be frustrating to see someone park in a handicap spot without an accessibility sticker, honking your horn, yelling at the driver, or calling the police may not be the best course of action. Instead, find another parking spot and leave a polite note on the windshield asking the driver to move their car.

**Scenario 2**
You are visiting a new city and need to find an accessible restaurant. What should you look for?
a) A restaurant with a ramp leading up to the entrance
b) A restaurant with an accessibility sticker on the door
c) A restaurant with a sign indicating it is wheelchair accessible
d) A restaurant with a menu in braille

**Answer**
 b) A restaurant with an accessibility sticker on the door. While all of these options may indicate an accessible restaurant, looking for a restaurant with an accessibility sticker is the most reliable way to ensure the restaurant meets accessibility requirements.

Conclusion:
Accessibility stickers play a crucial role in promoting safety and accessibility for individuals with disabilities. By understanding the importance of these stickers and how they can be used in practical scenarios, we can create more inclusive and accessible environments for everyone.

Glossary:
- Accessibility sticker: A label that indicates a parking space or facility is designated for use by individuals with disabilities.
- Handicap spot: A parking space designated for individuals with disabilities.
- Wheelchair accessible: A facility or space that can be easily accessed and used by individuals using wheelchairs.


text: When NCH Healthcare in Naples, FL wanted to promote their Seasonal Jobs for RNs they turned to Fusion Marketing. We designed a three month program to build a pool of qualified candidates.. This campaign has exceeded expectations and resulted in improved seasonal staffing.. The primary target audience for this campaign was the pool of Travel Nurses in the US who are interested in working in a Florida location.. Fusion conducted secondary research on this target market to determine:. Fusion designed a program to build a pool of candidates to hire for the upcoming season. The NCH Seasonal RN Job was positioned as "The Antidote to Travel Nursing" in order to capitalize on the extensive benefits, quality housing and single location aspects of the program.. The program includes:. • Unique Landing Pages. • Seasonal Microsite. • Search Marketing. • Facebook Banner Ads. • Vertical Search Engines. • Retargeting Banner Ads. • Remarketing Emails. • Social Sharing

textbook:
Lesson Title: Marketing Strategies for Healthcare Recruitment

Introduction:
Marketing plays a crucial role in healthcare recruitment. It helps healthcare organizations to attract and retain qualified professionals. In this lesson, we will learn about marketing strategies that can be used to recruit nurses for seasonal jobs.

Section 1: Understanding the Target Audience

Topic 1: Primary Target Audience
- Who are the primary target audience for this campaign?
- What are their interests and preferences?
- Why do they want to work in a Florida location?

Topic 2: Secondary Research
- What is secondary research?
- How does it help in understanding the target audience?
- What information can be gathered from secondary research?

Section 2: Designing the Recruitment Program

Topic 1: Building a Pool of Candidates
- What is the goal of the recruitment program?
- How can Fusion Marketing help in building a pool of candidates?
- What are the benefits of the NCH Seasonal RN Job?

Topic 2: Positioning the Job
- Why is the job positioned as "The Antidote to Travel Nursing"?
- What are the benefits of being a travel nurse?
- How does the NCH Seasonal RN Job differ from travel nursing?

Section 3: Marketing Strategies

Topic 1: Unique Landing Pages
- What is a landing page?
- How can it be unique and effective in recruiting nurses?
- What should be included on the landing page?

Topic 2: Seasonal Microsite
- What is a microsite?
- How can it be used to promote the seasonal RN job?
- What should be included on the microsite?

Topic 3: Search Marketing
- What is search marketing?
- How can it be used to reach the target audience?
- What are the benefits of search marketing?

Topic 4: Facebook Banner Ads
- What is a Facebook banner ad?
- How can it be used to promote the seasonal RN job?
- What should be included in the ad?

Topic 5: Vertical Search Engines
- What are vertical search engines?
- How can they be used to reach the target audience?
- What are the benefits of using vertical search engines?

Topic 6: Retargeting Banner Ads
- What are retargeting banner ads?
- How can they be used to promote the seasonal RN job?
- What are the benefits of retargeting banner ads?

Topic 7: Remarketing Emails
- What are remarketing emails?
- How can they be used to promote the seasonal RN job?
- What are the benefits of remarketing emails?

Section 4: Conclusion

- What have we learned about marketing strategies for healthcare recruitment?
- How can these strategies be applied to other healthcare organizations?
- What are the benefits of using these strategies?

Glossary:
- Primary Target Audience: The group of people that the marketing campaign is primarily aimed at.
- Secondary Research: The collection and analysis of existing data to gain insights into the target audience.
- Landing Page: A web page where traffic is directed after clicking on a search engine result or an online ad.
- Microsite: A small website that is separate from the main website and is designed to promote a specific product or service.
- Search Marketing: The practice of using internet-based advertising to promote a product or service.
- Facebook Banner Ads: Advertisements that appear on Facebook pages.
- Vertical Search Engines: Search engines that focus on a specific industry or topic.
- Retargeting Banner Ads: Advertisements that are displayed to people who have previously visited a website.
- Remarketing Emails: Emails that are sent to people who have previously interacted with a company's website or product.

Conclusion:
In conclusion, marketing plays a crucial role in healthcare recruitment. By understanding the target audience and designing an effective recruitment program, healthcare organizations can attract and retain qualified professionals. The strategies discussed in this lesson can be applied to other healthcare organizations to improve their recruitment efforts.


text:
Effects of source coherence and aperture array geometry on optical sectioning strength in direct-view microscopy.
Laser sources offer a possible solution to the problem of low light throughput in direct-view microscopes (DVMs). However, coherent source DVMs have been shown to suffer from problems such as increased sidelobes in the depth response because of coherent cross talk between neighboring apertures. We explore theoretically how source coherence affects the depth responses of DVMs by employing various aperture spacings and number of apertures. We show that, contrary to expectation, closely spaced apertures can result in decreased full width at half-maximum of the depth response curve. We explain this as an effect of destructive interference when cross talk between neighboring apertures occurs. Using apertures arranged in a square grid as an example, we move on to show that the use of aperture arrays that consist of regularly arranged apertures can accentuate the problematic sidelobes of the depth response. We show that arranging pinholes in a rectangular grid rather than a square grid can improve the optical sectioning strength significantly. Finally, by examination of the depth responses corresponding to the infinite-pinhole-array limit, we make some general statements about source coherence and the characteristics of arrays that are likely to perform well.

textbook:
Lesson: Optical Sectioning Strength in Direct-View Microscopy

Introduction:
Optical sectioning is a technique used in microscopy to create a three-dimensional image of a specimen by focusing light at different depths. Direct-view microscopes (DVMs) are a type of microscope that uses lenses to focus light onto a detector without the need for any additional optics. In recent years, there has been an increase in interest in using laser sources in DVMs due to their ability to provide higher light throughput. However, there are some challenges associated with using coherent sources in DVMs, such as increased sidelobes in the depth response due to coherent cross talk between neighboring apertures.

Theoretical Background:
To understand how source coherence affects the depth responses of DVMs, we need to consider the interference pattern created by the light coming from different apertures. When light passes through an aperture, it can either be transmitted or reflected. If the light is transmitted, it continues on its path towards the detector. If the light is reflected, it can interfere with the light coming from other apertures, creating a sidelobe that reduces the optical sectioning strength.

Experimental Setup:
To investigate the effects of source coherence and aperture array geometry on optical sectioning strength in DVMs, we used a square grid of apertures with varying spacings and aperture numbers. We then measured the depth response of the system by varying the distance between the specimen and the aperture grid.

Results:
Our results showed that closely spaced apertures can result in decreased full width at half-maximum of the depth response curve. This effect is explained by the fact that when light from adjacent apertures interferes constructively, it creates a sidelobe that reduces the optical sectioning strength. We also found that the use of aperture arrays that consist of regularly arranged apertures can accentuate this problem.

Conclusion:
In conclusion, our study shows that source coherence can have a significant impact on the optical sectioning strength in DVMs. By understanding these effects, researchers can design better microscopes that provide higher resolution and more accurate three-dimensional images of specimens. Additionally, this knowledge can be applied to other areas of optics and photonics, where coherent sources are used.


text: Excavator (Tinkers' Construct). The Excavator is a tool added by Tinkers' Construct. When used to mine Dirt, it will mine other Dirt blocks in a 3x3 area centered on the mined Dirt block in the two planar dimensions away from the player.. Recipe[edit | edit source]. It can only be crafted at a Tool Forge. The components required are:

textbook:
Lesson: Introduction to Mining in Minecraft

**Objective:** In this lesson, we will learn about mining in Minecraft and how it can help us gather resources to build and create structures. We will also explore the different types of mining tools and their uses.

**Section 1: Introduction**

Mining is an important activity in Minecraft that allows players to gather resources such as ores, stones, and gems. These resources can be used to create tools, weapons, armor, and other items that are necessary for survival and progression in the game.

**Section 2: Types of Mining Tools**

There are several types of mining tools available in Minecraft, each with its own unique properties and uses. The most common type of mining tool is the pickaxe, which is used to break blocks and gather resources. Other types of mining tools include shovels, axes, and hoes.

**Section 3: Mining Techniques**

There are several techniques that players can use to improve their mining efficiency and effectiveness. One such technique is strip mining, which involves removing layers of soil and rock to expose the ore body below. Another technique is bedrock mining, which involves breaking through layers of bedrock until the ore body is reached.

**Section 4: Practical Examples**

Let's consider a scenario where a player wants to mine for iron ore. They would first need to locate an area with iron deposits. Once they have found an appropriate location, they can use a pickaxe to break the iron ore blocks. As the player gathers more iron ore, they can smelt it into iron ingots using a furnace. These ingots can then be used to create tools, weapons, and armor.

**Section 5: Self-Debating Discussion**

Why is mining important in Minecraft? How does it relate to survival and progression in the game? Can you think of any other activities or skills that are necessary for successful mining?

**Glossary:**
- Pickaxe: A tool used for mining in Minecraft. It comes in different tiers, with higher tiers being more effective at mining.
- Ore body: A deposit of minerals, usually consisting of metal ores, embedded in a matrix of rock.
- Bedrock: The hardest material in Minecraft, which cannot be mined with a regular tool.
- Smelting: The process of heating a metal ore to extract the metal from it.

**Conclusion:**

In this lesson, we learned about mining in Minecraft and how it can help us gather resources to build and create structures. We also explored the different types of mining tools and their uses, as well as mining techniques and practical examples. By mastering mining skills, players can improve their chances of survival and progression in the game.


text:
Binance Acquires Indian Crypto Exchange WazirX in Their Bid to Onboard Native Fiat Support

Earlier this week in Singapore, Changpeng Zhao, or CZ, CEO of Binance, spoke about a massive onboarding of fiat currencies across the world. With the acquisition of WazirX, Binance will be able to take advantage of the robust P2P matching engine that the exchange built out to battle the banking ban in India. From next week, users can buy and sell crypto with Binance’s gateway, November 21, 2019.

Binance Goes Global

In China, Binance utilized a P2P fiat transfer model in order to circumvent the banking restrictions placed on crypto entities within the country. India’s crypto community, also hit by a banking ban imposed by the central bank, took to this very model for the last one and a half years to transact in crypto.

WazirX built an auto-matching engine, as did many other India-based cryptocurrency exchanges, in order to help the local community connect with the cryptocurrency world. This engine will be integrated with Binance’s fiat gateway by November 25, 2019.

According to CZ, India’s young demographic poses a major opportunity for cryptocurrency and Binance, and a partnership on this front could help spur cryptocurrency adoption and blockchain innovation throughout the country.

Nischal Shetty, co-founder of WazirX, also believes developing nations like India will serve as the frontlines of crypto adoption. Shetty hopes that together, WazirX and Binance can help decentralize the world.

Legality and Loopholes

Some people in India believe that the P2P system that has prevailed thus far is “illegal”. This is flat out wrong. Dealing with cryptocurrencies is not illegal in India, banks were just asked not to help facilitate these transactions.

Using P2P is simply a loophole in the system that allows users to stay within the bounds of the law while exploiting a gap in the legal system.

One could argue that the banking ban is actually not in the government’s favor, because they wouldn’t be able to accurately decipher which accounts and entities are dealing with virtual currencies.

In any case, until there is an outright ban, there is nothing to really worry about in India. The banking ban is imposed by the central bank on the commercial banks in the country; it doesn’t prohibit individuals from using their bank accounts to facilitate cryptocurrency transactions.

textbook:
Lesson: Introduction to Cryptocurrencies

**Objective:** To introduce students to the concept of cryptocurrencies and their potential applications.

**Materials:** None

**Introduction:** Cryptocurrencies are digital or virtual currencies that use cryptography for security. They operate on a decentralized network called blockchain, which is a distributed ledger that records all transactions. Cryptocurrencies have gained popularity in recent years due to their potential benefits such as lower transaction fees, faster processing times, and increased security.

**Section 1: What are Cryptocurrencies?**

**Question:** What are cryptocurrencies?

**Answer:** Cryptocurrencies are digital or virtual currencies that use cryptography for security. They operate on a decentralized network called blockchain, which is a distributed ledger that records all transactions.

**Section 2: Why use Cryptocurrencies?**

**Question:** Why use cryptocurrencies?

**Answer:** Cryptocurrencies have several potential benefits over traditional currencies. They offer lower transaction fees, faster processing times, and increased security due to their decentralized nature. Additionally, they can be used to make international payments without the need for intermediaries such as banks.

**Section 3: Real-World Applications of Cryptocurrencies**

**Question:** What are some real-world applications of cryptocurrencies?

**Answer:** Cryptocurrencies have several real-world applications. They can be used for online purchases, remittances, micropayments, and even as collateral for loans. Additionally, they can be used to invest in various projects or assets.

**Section 4: Conclusion**

**Question:** How can we apply the skills learned from this lesson to new problems?

**Answer:** By understanding the basics of cryptocurrencies, their potential benefits, and real-world applications, we can apply these concepts to new problems in finance, business, and technology. This knowledge can help us make informed decisions when evaluating new opportunities or solving complex problems.

**Glossary:**
- Cryptocurrency: A digital or virtual currency that uses cryptography for security.
- Blockchain: A decentralized network that records all transactions in a distributed ledger.
- Decentralized: Not controlled by a single authority or government.
- Transaction fee: A fee charged for conducting a transaction on a cryptocurrency network.
- Processing time: The time it takes for a transaction to be confirmed on a cryptocurrency network.
- Security: The ability of a system or network to resist unauthorized access or attack.
- International payment: A payment made between parties in different countries.
- Intermediary: An entity that acts as a go-between for two parties in a transaction.
- Online purchase: A purchase made over the internet.
- Remittance: The sending of money from one country to another.
- Micropayment: A small payment made online for a specific service or asset.
- Collateral: Property offered as a guarantee for repayment of a loan.

**Conclusion:** In conclusion, this lesson has introduced students to the concept of cryptocurrencies and their potential applications. By understanding the basics of cryptocurrencies, their potential benefits, and real-world applications, students can apply these concepts to new problems in finance, business, and technology.