text:
Win or lose, Villanova has already added over $8.5 million to the Big East’s coffers by making it to the title game of the 2016 NCAA Tournament. Butler, Providence and Xavier have each brought more than $3.4 million back to the league by making it the Round of 32 and Seton Hall earned over $1.7 million just by being in the party for a day. This is the other side of winning in March that is so critical for the Big East. The 10 member schools that make up this configuration of the Big East conference have a lot in common as institutions, which is partly why they believe their marriage is made in heaven. Besides their love for basketball, the Big East member institutions don’t have the financial backing of their home state to help drive their athletic programs to championship heights.

Most of their funds come in the form of donations, a fundraising avenue that has grown exponentially at a school like Providence during Ed Cooley’s tenure as the head coach in Friartown. Another important boost to athletic budgets in the Big East is money shared from NCAA Tournament units. These units are awarded to a team for making the NCAA Tournament and winning games. For example, Providence got a unit for making the field as an at-large and they earned an additional unit by beating USC in the First Round. Their 2 units go into a pool with the rest of the Big East’s units earned by the other 4 teams in this year’s NCAA Tournament. Each unit possesses a dollar figure that the league will receive from the NCAA’s “Basketball Fund”, a pool made up of money the NCAA gets from their TV deals and other revenues associated with the NCAA Tournament each year. In 2015-16, the NCAA planned to distribute $205 million from the “Basketball Fund”, which accounted for 37% of the $544 million available for distribution that year.

Year Estimated Unit Value 2017 $ 267,320.00 2018 $ 274,003.00 2019 $ 280,853.08 2020 $ 287,874.40 2021 $ 295,071.26 2022 $ 302,448.04

Villanova’s run to the Final Four earned 5 units — units are not awarded beyond the Final Four — with the value of a unit in 2017 expected to be around $267,320. A unit’s value increases each year and the payouts are done on a rolling basis over the course of 6 years. That means that the Big East’s 12 units earned during the 2016 NCAA Tournament are likely to be worth more than $20 million by the time the final payout is made in 2022. An equal distribution of the money means each school would get more than $2 million between 2017 and 2022, which is about 50% as much as each school gets from the TV deal with Fox annually. In other words, this money will be a nice boost to each school’s athletic budget over the next several years.

Year Estimated Value of 12 Units 2017 $ 3,207,840.00 2018 $ 3,288,036.00 2019 $ 3,370,236.90 2020 $ 3,454,492.82 2021 $ 3,540,855.14 2022 $ 3,629,376.52 Total Value $ 20,490,837.39

Winning games in the NCAA Tournament was critical for the Big East’s perception as a viable power conference for men’s basketball. Villanova getting all the way to the final night of the season certainly made people realize that the need for a requiem for the Big East may have been premature. It also has the added benefit of paying off in real dollars and cents. The league has managed to get 40%, 60% and 50% of the league into the NCAA Tournament in the first 3 years of this current configuration. Disappointing showings the first 2 years were problematic, but Jay Wright’s crew lopping the head off a Big 12 Goliath en route to a date with an ACC blueblood has certainly made up for the failings of years 1 and 2. The future looks bright for this major basketball conference and each league member will have some additional funds to ensure that times remain good in Big East land.

Year Equal Share/School 2017 $ 320,784.00 2018 $ 328,803.60 2019 $ 337,023.69 2020 $ 345,449.28 2021 $ 354,085.51 2022 $ 362,937.65

See how much each school contributed:

Follow me on Twitter @pcbb1917

Liked it? Take a second to support pcbb1917.com on Patreon!

textbook:
Lesson: Introduction to Financial Aid in College Sports

### Section 1: The Importance of Financial Aid in College Sports

College sports are a big business. They generate millions of dollars in revenue for universities and conferences. However, not all colleges have the same financial resources. Some colleges rely heavily on financial aid to support their athletic programs. In this lesson, we will learn about the importance of financial aid in college sports and how it affects the Big East Conference.

### Section 2: How Financial Aid Works in College Sports

Financial aid is money given or loaned to students to help them pay for college. In college sports, financial aid can come in the form of scholarships, grants, and loans. These funds are used to cover the costs of tuition, room and board, books, and other expenses.

The Big East Conference is made up of 10 member institutions that share a common bond - their love for basketball. These institutions don't have the financial backing of their home state to help drive their athletic programs to championship heights. As a result, they rely heavily on financial aid to support their athletes.

### Section 3: The Impact of Financial Aid on the Big East Conference

Financial aid plays a crucial role in the success of the Big East Conference. The conference generates millions of dollars in revenue from television contracts, ticket sales, and sponsorships. However, without financial aid, many of the member institutions would not be able to compete at the highest level.

For example, Providence University has seen a significant increase in donations since the arrival of head coach Ed Cooley. These donations have helped the school invest in its athletic program and compete at a higher level. Additionally, the conference shares money from NCAA Tournament units with its member institutions. These units are awarded to a team for making the NCAA Tournament and winning games. This additional revenue helps to offset the costs of travel and other expenses associated with competing in the tournament.

### Section 4: The Importance of Financial Aid in College Sports

Financial aid is essential for the success of college sports, especially for conferences like the Big East that don't have the financial backing of their home state. Without financial aid, many of these institutions would not be able to compete at the highest level. Financial aid allows these schools to attract top-tier athletes and invest in their athletic programs, which ultimately leads to better competition and more exciting games for fans to enjoy.

### Glossary
- Financial aid: Money given or loaned to students to help them pay for college
- Scholarship: Money awarded to a student based on academic or athletic achievement
- Grant: Money awarded to a student based on financial need
- Loan: Money borrowed by a student to pay for college
- NCAA Tournament: An annual basketball tournament held by the National Collegiate Athletic Association (NCAA)
- Units: Money awarded to a team for making the NCAA Tournament and winning games

### Conclusion
In conclusion, financial aid is an essential component of college sports, particularly for conferences like the Big East that rely on it to compete at the highest level. By understanding the importance of financial aid and how it works, we can appreciate the hard work and dedication of these athletes and institutions even more.


text: !***** Brian Won's 20130105/index.htm version 0.2. Updated January 7, 2013! *****!>. UCLA vs. Stanford. UCLA vs. Stanford inside the newly renovated Pauley Pavilion.. Managed slightly different seats than the Cal game, a few rows higher up. Maybe a little higher is better? Not sure!. Some issues with free throws and whatnot, took a while to score in the beginning as well, but the team worked over the rough patches (which really weren't that bad, at least against a middling team like Stanford) for a 68-60 victory. GO BRUINS!. Wandered over to California Science Center afterwards to see Space Shuttle Endeavour in her new home. After all the fuss over Endeavour's arrival and trek across town, how could we not see Endeavour at California Science Center? *grins*. Endeavour's permanent digs will probably be much more impressive when they're done, but in the meantime, her temporary home is just fine! After all that excitement, we had a quick dinner at Natalee Thai to fill starving bellies.

source: refinedweb

textbook:
Lesson: Extracting Core Values from Text

Introduction:
In this lesson, we will learn how to extract core values from a text paragraph. We will use the input text provided above to demonstrate the process.

Core Value:
The core value that we can extract from the input text is the importance of persistence and hard work. This is evident from the way the UCLA basketball team managed to overcome some initial difficulties and eventually win the game against Stanford. Similarly, the team's determination to see Endeavour at the California Science Center despite the fuss and difficulty involved in its transportation also highlights the value of persistence and hard work.

Lesson:
1. What is the core value that we can extract from the input text?
2. How does the UCLA basketball team demonstrate the importance of persistence and hard work?
3. What is the significance of seeing Endeavour at the California Science Center?
4. Why is it important to persist and work hard towards achieving our goals?
5. Can you think of any other examples where persistence and hard work have led to success?

Conclusion:
In this lesson, we have learned about the importance of persistence and hard work in achieving our goals. We have also seen how the UCLA basketball team and the transportation of Endeavour to the California Science Center demonstrate this core value. By applying these principles to our own lives, we can achieve success and fulfillment in our endeavors.


text: NEW YORK, June 11 – Canada’s Virtek Vision International said Monday that its Virtek ChipWriter and Virtek ChipReader had been selected for a six-month trial to apply its microarray technology for a neonatal screening application.. Under the terms of the alliance, Virtek has agreed to supply its spotter and reader to Neo Gen Screening and TeleChem International/ArrayIt.com for the testing of metabolic disorders in newborns. TeleChem of Sunnyvale, Calif., has developed the assays while Neo Gen Screening of Pittsburgh, Pa., develops tests for screening disorders.

textbook:
**Lesson: Introduction to Microarray Technology**

## Section 1: What is Microarray Technology?

Microarray technology is a powerful tool used in biology, genetics, and medicine to study gene expression, identify genetic variations, and detect diseases. It involves the use of small arrays or chips containing thousands of DNA spots or molecules, each representing a specific gene or target sequence. These chips can be used to analyze the expression of multiple genes simultaneously, making it faster and more cost-effective than traditional methods.

## Section 2: How does Microarray Technology work?

Microarray technology works by hybridizing or binding labeled DNA or RNA samples to specific locations on the chip. The labeled nucleotides in the sample bind to complementary sequences on the chip, creating a pattern of fluorescent spots that can be scanned and analyzed. The intensity of the fluorescence is proportional to the amount of target sequence present, allowing researchers to determine which genes are expressed at high levels and which are not.

## Section 3: Applications of Microarray Technology

Microarray technology has many applications in biology and medicine, including:

- Gene expression analysis: Researchers can use microarrays to study which genes are turned on or off in response to certain conditions or treatments.
- Genotyping: Microarrays can be used to identify specific genetic variations or mutations associated with diseases or traits.
- Disease detection: Microarrays can be used to detect the presence of specific pathogens or cancer cells in a sample.
- Drug discovery: Microarrays can be used to screen compounds for their ability to affect gene expression or cellular processes.

## Section 4: Practical Examples

One practical example of microarray technology is the Human Genome U133 Plus 2.0 Array, which contains probes for over 44,000 transcripts and variants. This array can be used to study gene expression changes in response to various stimuli, such as drugs or environmental factors. Another example is the use of microarrays in cancer research, where researchers can analyze the expression of thousands of genes simultaneously to identify potential biomarkers or therapeutic targets.

## Section 5: Critical Thinking Questions

1. What are some advantages of using microarray technology compared to traditional methods?
2. How might microarray technology be used to improve our understanding of complex biological processes or diseases?
3. What are some potential limitations or challenges associated with microarray technology?

## Glossary
- Hybridization: The process of binding labeled nucleotides to complementary sequences on a microarray chip.
- Array: A small chip containing thousands of DNA spots or molecules, each representing a specific gene or target sequence.
- Fluorescence: The emission of light by a substance when it is excited by radiation or energy.
- Gene expression: The process by which information from a gene is used to synthesize functional gene products, such as proteins.
- Mutation: A change in the DNA sequence that can result in a altered protein or function.

## Conclusion

Microarray technology is a powerful tool that has revolutionized the field of biology and medicine. By allowing researchers to study gene expression and identify genetic variations, it has opened up new avenues for understanding complex biological processes and developing targeted therapies for diseases. As with any technology, there are limitations and challenges, but the potential benefits make it a valuable tool for scientists and clinicians alike.


text: Day CarePartnership for Children of Cumberland County provides programs and support for families with children birth to 5 years old. We have been a leader in early childhood since 1993.351 Wagoner Dr., Ste 200Fayetteville, NC 28303Business Directory News Releases Events Calendar Hot Deals Member To Member Deals Marketspace Job Postings Contact Us Information & Brochures Weather Join The Chamber

textbook:
**Lesson: Identifying Key Information from Text**

**Objective:** Students will learn how to identify key information from a text by analyzing its structure and content.

**Grade Level:** Primary through High School

**Introduction:** In this lesson, we will learn how to identify key information from a text by analyzing its structure and content. This skill is essential for understanding and retaining information from various sources such as books, articles, and websites.

**Section 1: Analyzing the Text**

1. Start by reading the text carefully to understand its main purpose.
2. Look for headings, bolded text, or any other formatting that may indicate important information.
3. Identify the author's tone and point of view, as this can help you understand their perspective on the topic.
4. Pay attention to any facts, figures, or statistics that are presented in the text.
5. Take note of any opinions or conclusions that the author presents.

**Section 2: Identifying Key Information**

1. What is the main purpose of the text?
2. Who is the target audience?
3. What are the key points or arguments presented in the text?
4. Are there any facts, figures, or statistics that support these points?
5. What is the author's tone and point of view?
6. Are there any opinions or conclusions presented in the text?

**Section 3: Applying the Skill**

1. Read the following passage and identify the key information:

   Partnership for Children of Cumberland County provides programs and support for families with children birth to 5 years old. We have been a leader in early childhood since 1993.351 Wagoner Dr., Ste 200Fayetteville, NC 28303Business Directory News Releases Events Calendar Hot Deals Member To Member Deals Marketspace Job Postings Contact Us Information & Brochures Weather Join The Chamber

2. Based on the passage, what is the main purpose of Partnership for Children of Cumberland County?
3. Who is the target audience for their programs and services?
4. What are some key points or arguments presented in the passage?
5. Are there any facts, figures, or statistics that support these points?
6. What is the author's tone and point of view?
7. Are there any opinions or conclusions presented in the passage?

**Conclusion:** By analyzing the structure and content of a text, we can identify key information that is important for understanding the main purpose and message of the author. This skill is useful for a variety of tasks, including research, writing, and critical thinking.

**Glossary:**
- Text: A written or printed work.
- Headings: A heading is a title or caption that precedes a section of text, such as a chapter or subsection.
- Bolded text: Text that is emphasized by being written in bold font.
- Formatting: The arrangement of text and images on a page.
- Tone: The author's attitude towards the subject matter or audience.
- Point of view: The author's perspective on the topic or issue being discussed.
- Facts: Statements that are supported by evidence or research.
- Figures: Numbers or illustrations used to represent data or information.
- Statistics: Numerical data that is collected and analyzed to describe a phenomenon.
- Opinions: Personal beliefs or attitudes about a topic or issue.


text: Mona Hatoum. Mona Hatoum (British/Palestinian) unites in her work an interest in aesthetics with themes that are political or social by focusing on conflicted subjects such as violence, oppression, and voyeurism, often in relation to the human body. Her art is located on the border between reality and illusion, where recognizable everyday objects are distorted and transformed into unpleasant and sometimes physically dangerous objects. Rubber crutches, a carpet of pins, and electrified kitchen utensils are a few examples of Hatoum’s unique body of work. The exhibition at Magasin 3 Stockholm Konsthall includes around 60 artworks, as well as a large-scale installation made specifically for Magasin 3. Hatoum has exhibited widely in Europe, USA, and Canada. In 1995, she was nominated for the Turner Prize and was included in the Venice Biennial.

textbook:
Lesson: Introduction to Contemporary Art - Mona Hatoum

**Overview:** In this lesson, we will explore the work of contemporary artist Mona Hatoum. We will analyze her artistic style, themes, and techniques, and examine how they reflect current societal issues.

**Objectives:**
- To introduce students to the work of contemporary artist Mona Hatoum.
- To analyze her artistic style, themes, and techniques.
- To examine how her work reflects current societal issues.
- To understand the importance of art in addressing social and political concerns.

**Section 1: Introduction to Mona Hatoum**

**Topic:** Introduction to Mona Hatoum

**Activity:** Watch the video below to learn about Mona Hatoum's life and work.

[embed]https://www.youtube.com/watch?v=f_yXyO37YR4[/embed]

**Discussion:** After watching the video, answer the following questions in your notebook.

1. Where was Mona Hatoum born?
2. What is her nationality?
3. What is her artistic style?
4. What are some themes in her work?
5. How does she use everyday objects in her art?
6. What is the significance of her work?

**Section 2: Analyzing Mona Hatoum's Art**

**Topic:** Analyzing Mona Hatoum's Art

**Activity:** Let's analyze two of Mona Hatoum's artworks: "Soap Bubble" and "Cut".

[soap-bubble]

**Discussion:** What do you think is the meaning behind "Soap Bubble"? How does it relate to current societal issues?

[cut]

**Discussion:** What do you think is the meaning behind "Cut"? How does it relate to current societal issues?

**Section 3: Conclusion**

**Topic:** Conclusion

**Activity:** Create a piece of art that reflects a current societal issue. Use materials that are commonly found in everyday life.

**Discussion:** Share your artwork with the class and explain how it relates to a current societal issue.

**Glossary:**
- Contemporary Art: Art created during the late 20th century and early 21st century.
- Themes: Topics or subjects explored in art.
- Techniques: Methods used by artists to create their work.
- Societal Issues: Problems or concerns affecting society.

**Conclusion:** In this lesson, we learned about the work of contemporary artist Mona Hatoum. We analyzed her artistic style, themes, and techniques, and examined how her work reflects current societal issues. We also created our own artwork to demonstrate our understanding of the importance of art in addressing social and political concerns. By studying the work of artists like Mona Hatoum, we can gain a deeper appreciation for the role of art in our society.


text: State of Illinois Medical Cannabis Dispensary Selection Form. Request for transfer to Mission Illinois – 8554 Commercial Ave, Chicago 60617, District 42-001. Under Illinois law, registered medical cannabis patients must select a dispensary in order to purchase medicine. Whether you’re a new patient selecting a dispensary for the first time or an existing patient who wants to select a new dispensary, the change requires filing paperwork with the Illinois Department of Public Health.. If you’d like Mission to be your dispensary, please fill out the form below and we’d be happy to file the paperwork on your behalf. Please note that once the paperwork is submitted, it will take up to 48 hours for the Illinois Department of Public Health to process it and provide you with confirmation.

textbook:
Lesson Title: How to Select a Medical Cannabis Dispensary in Illinois

Introduction:
In this lesson, we will learn about the process of selecting a medical cannabis dispensary in Illinois. We will cover the steps involved, the required documentation, and the criteria to consider when choosing a dispensary. By the end of this lesson, you will be able to understand the importance of selecting the right dispensary and how to go about it.

Section 1: Overview of the Process

Topic 1: Steps Involved in Selecting a Medical Cannabis Dispensary
- The first step is to ensure that you are a registered medical cannabis patient in Illinois.
- Once you have confirmed your registration status, you can begin the process of selecting a dispensary.
- You will need to fill out a dispensary selection form, which can be obtained from the Illinois Department of Public Health (IDPH) website.
- The form requires you to provide information such as your name, address, and medical cannabis registry identification card number.
- After filling out the form, you will need to submit it to the IDPH along with any necessary documentation.
- Once the IDPH has processed your application, you will receive confirmation that your dispensary selection has been approved.

Topic 2: Required Documentation
- To select a medical cannabis dispensary in Illinois, you will need to provide the following documentation:
  - A copy of your Illinois medical cannabis registry identification card
  - A completed dispensary selection form
  - Proof of residency (e.g., driver's license, state ID card)

Section 2: Criteria to Consider When Choosing a Dispensary

Topic 1: Location
- Consider the location of the dispensary in relation to your home or workplace.
- You may prefer a dispensary that is close to your home or workplace for convenience.
- However, you should also consider the proximity to public transportation, parking availability, and accessibility for individuals with disabilities.

Topic 2: Product Availability and Quality
- Consider the products available at the dispensary, including the strains, dosage forms, and potency levels.
- You may want to choose a dispensary that offers a wide variety of products or one that specializes in a particular type of product (e.g., edibles, topicals).
- Additionally, consider the quality of the products, including their potency, purity, and safety.

Topic 3: Services and Amenities
- Consider the services and amenities offered by the dispensary, such as online ordering, delivery, and in-store events.
- Some dispensaries may offer loyalty programs, discounts, or special promotions.
- You may also want to consider the dispensary's hours of operation, payment options, and return policies.

Section 3: Conclusion

By following the steps involved in selecting a medical cannabis dispensary in Illinois and considering the criteria discussed in this lesson, you can make an informed decision about which dispensary is best for you. Remember to carefully review the dispensary selection form and provide all necessary documentation to ensure a smooth and successful dispensary selection process.


text: Item Information. Title: Rubber underpants. Date: between 1949 and 1966?. Physical Details: 1 clothing ; 25 x 35 cm.. Description: Painter Clyfford Still sent this pair of rubber underpants to art critic, Emily Genauer after she reviewed his work unfavorably in the The New York Herald Tribune.. Note attached to front (handwritten): Hoping this will aid in concealing your Sunday afflictions. With the compliments of Clyfford Still.. Date range based on the years when Genauer was chief art critic at the Herald Tribune.. Creator: Unidentified. Forms part of: Emily Genauer papers, circa 1920-1990. Rights Statement: Current copyright status is undetermined. Citation Information: Rubber underpants, between 1949 and 1966?. Emily Genauer papers, circa 1920-1990. Archives of American Art, Smithsonian Institution.. Digital ID: 11638

textbook:
Lesson: How to Read and Understand Historical Documents

Introduction:
In this lesson, we will learn how to read and understand historical documents. We will analyze the item information of a pair of rubber underpants sent by painter Clyfford Still to art critic Emily Genauer. We will use this document to learn about the context, tone, and language of historical documents.

Section 1: Reading Historical Documents

Topic: Understanding Historical Context

Question: What was the historical context of the rubber underpants?
Answer: The rubber underpants were sent between 1949 and 1966, during which time Emily Genauer was the chief art critic at The New York Herald Tribune.

Topic: Analyzing Tone and Language

Question: How do you determine the tone of the message?
Answer: The tone of the message is sarcastic and playful, as indicated by the note attached to the front of the underpants.

Topic: Identifying Key Information

Question: What can you infer about the relationship between Clyfford Still and Emily Genauer?
Answer: From the message, it appears that there was some tension between the two, as Clyfford Still sent the underpants in response to a negative review of his work by Genauer.

Section 2: Analyzing Historical Documents

Topic: Identifying Context Clues

Question: What clues can you find in the item information that help you understand the historical context of the rubber underpants?
Answer: The physical details of the underpants (1 clothing; 25 x 35 cm) and the date range (between 1949 and 1966) provide context for the historical period in which the underpants were sent.

Topic: Interpreting Language and Imagery

Question: How does the note attached to the front of the underpants contribute to the tone and meaning of the message?
Answer: The note adds a humorous touch to the message, implying that the underpants will help Genauer cope with her "Sunday afflictions." This language suggests a playful tone and a lighthearted relationship between Still and Genauer.

Section 3: Applying Historical Skills

Topic: Making Connections Across Time and Place

Question: How might the rubber underpants be connected to other historical events or figures?
Answer: The rubber underpants could be connected to the broader cultural and artistic movements of the mid-20th century, such as the rise of abstract expressionism or the growing influence of pop art.

Topic: Evaluating Evidence

Question: How might you evaluate the reliability of the item information?
Answer: One might consider the source of the item information (the Archives of American Art) and the credibility of Emily Genauer as a chief art critic at The New York Herald Tribune. Additionally, one could compare the item information to other sources or primary documents to verify its accuracy.

Conclusion:
In this lesson, we have learned how to read and interpret historical documents by analyzing the item information of a pair of rubber underpants. By examining the historical context, tone, and language of the message, we can gain a deeper understanding of the relationship between Clyfford Still and Emily Genauer. We have also applied historical skills by making connections across time and place and evaluating evidence. By practicing these skills, we can become more skilled historians and better equipped to understand the past.

Glossary:
- Historical Documents: Written or physical evidence that provides information about past events or people.
- Context: The background circumstances or environment in which an event occurs or a document is written.
- Tone: The attitude or mood conveyed by a piece of writing or speech.
- Key Information: Important facts or details that are necessary for understanding a topic or situation.
- Context Clues: Hints or cues within a text that help readers understand its meaning.
- Imagery: The use of descriptive language or sensory details to create mental images or pictures.
- Playful: Showing a lighthearted or teasing quality.
- Abstract Expressionism: An art movement characterized by non-representational or non-objective works, often created through spontaneous or gestural brushstrokes.
- Pop Art: An art movement that emerged in the mid-20th century, characterized by the use of mass-produced images, symbols, and objects.


text: Ancor Transport can manage your entire freight logistics needs: from a single shipment, all the way up to creating a comprehensive, custom-configured logistics solution.. With over 12 years of expereince we have built a strong and satisfied customer base. We serve each customer with the highest commitment to outstanding logistics services.. For you, this means designing the most cost effective end-to-end transportation solution that provides consistent and on-time delivery.. Contact us today to find out how to improve both your freight services and your bottom line.

textbook:
**Lesson: Logistics Management**

**Introduction**

Logistics management is the process of planning, coordinating, and controlling the flow of goods, services, and information from supplier to end user. It involves managing inventory, transportation, and warehousing to ensure that products are delivered on time and at the lowest possible cost. In this lesson, we will learn about the importance of logistics management, its components, and how it can be applied to various industries.

**Core Value**

The core value of logistics management is efficiency. By optimizing the flow of goods and services, businesses can reduce costs, increase profits, and improve customer satisfaction. Logistics management also helps businesses to stay competitive by ensuring that products are delivered on time and at the lowest possible cost.

**Section 1: Introduction to Logistics Management**

**Topic 1: Importance of Logistics Management**

Logistics management is essential for businesses of all sizes. It helps businesses to manage their inventory, transportation, and warehousing efficiently, which can lead to cost savings and improved customer satisfaction. Logistics management also helps businesses to stay competitive by ensuring that products are delivered on time and at the lowest possible cost.

**Topic 2: Components of Logistics Management**

The components of logistics management include inventory management, transportation management, and warehousing management. Inventory management involves managing the flow of goods from supplier to end user. Transportation management involves coordinating the movement of goods from one location to another. Warehousing management involves storing and handling goods in a warehouse.

**Section 2: Inventory Management**

**Topic 1: Purpose of Inventory Management**

The purpose of inventory management is to ensure that products are available when needed and at the lowest possible cost. Inventory management involves tracking inventory levels, ordering products, and managing inventory levels to ensure that products are available when needed.

**Topic 2: Techniques for Inventory Management**

There are several techniques for inventory management, including just-in-time (JIT) inventory management, materials requirement planning (MRP), and economic order quantity (EOQ) analysis. JIT inventory management involves ordering products only when they are needed, which can reduce inventory costs. MRP involves forecasting demand and ordering products accordingly. EOQ analysis involves determining the optimal order quantity to minimize inventory costs.

**Section 3: Transportation Management**

**Topic 1: Purpose of Transportation Management**

The purpose of transportation management is to coordinate the movement of goods from one location to another. This involves coordinating shipping and receiving, tracking shipments, and managing transportation costs.

**Topic 2: Techniques for Transportation Management**

There are several techniques for transportation management, including route optimization, load consolidation, and carrier selection. Route optimization involves determining the most efficient route for deliveries. Load consolidation involves combining shipments to reduce transportation costs. Carrier selection involves choosing the most cost-effective transportation method.

**Section 4: Warehousing Management**

**Topic 1: Purpose of Warehousing Management**

The purpose of warehousing management is to store and handle goods in a warehouse. This involves managing inventory levels, picking orders, and packing orders.

**Topic 2: Techniques for Warehousing Management**

There are several techniques for warehousing management, including ABC analysis, zone picking, and pallet racking. ABC analysis involves categorizing inventory into three categories based on usage frequency. Zone picking involves grouping similar items together to improve picking efficiency. Pallet racking involves storing products on pallets to improve storage density.

**Glossary**

- Inventory: A stock of goods or materials
- Transportation: The movement of goods or people from one place to another
- Warehouse: A building or area for storing goods

**Conclusion**

Logistics management is an essential part of business operations. By optimizing the flow of goods and services, businesses can reduce costs, increase profits, and improve customer satisfaction. Throughout this lesson, we have learned about the importance of logistics management, its components, and how it can be applied to various industries. By applying these concepts, businesses can improve their logistics operations and stay competitive in the marketplace.


text: 1. After eight years of development, Esteyco moves a step further in the demonstration of its revolutionary substructure system for offshore wind turbines, with the construction of a full-scale operational prototype at Gran Canaria, Canary Islands.. The demonstrator is aimed to bring the technology to the highest trl (technology readiness level), and ready for commercial stages.. The prototype will be the first bottom fixed offshore wind turbine in Spain and in all of southern Europe, and the first one in the World ever to be installed with no need for heavy-lift offshore vessels or cranes, in a groundbreaking step which paves the way towards new capabilities for low cost deep offshore wind.

textbook:
**Title:** Building a Revolutionary Substructure System for Offshore Wind Turbines

**Introduction:**
In this lesson, we will learn about the development of a revolutionary substructure system for offshore wind turbines. This system has been designed to reduce the cost of installing wind turbines in deep water, making it more accessible for widespread use. We will explore the steps involved in building this prototype and the benefits it offers to the renewable energy industry.

**Section 1: Understanding the Problem**
The current methods of installing offshore wind turbines require heavy-lift offshore vessels or cranes, which can be expensive and time-consuming. This limits the ability to install wind turbines in deep water, where they could be more efficient. The goal of this project was to develop a new substructure system that could be installed without the need for these heavy-lift vessels or cranes.

**Section 2: Developing the Solution**
Esteyco, a company specializing in offshore wind infrastructure, spent eight years developing this revolutionary substructure system. The system is designed to be installed on the ocean floor, providing a stable foundation for the wind turbine. The prototype is being built in Gran Canaria, Canary Islands, and will be the first bottom-fixed offshore wind turbine in Spain and all of southern Europe.

**Section 3: Building the Prototype**
The prototype is a full-scale operational demonstrator, which means it is designed to be functional and ready for commercial use. It is being constructed using advanced engineering techniques, including computer-aided design (CAD) and computational fluid dynamics (CFD). These tools help engineers ensure that the prototype meets all necessary safety and performance requirements.

**Section 4: Benefits of the Prototype**
The benefits of this revolutionary substructure system are significant. Firstly, it eliminates the need for heavy-lift offshore vessels or cranes, reducing the cost and complexity of installing wind turbines in deep water. This makes it more accessible for widespread use, allowing for the expansion of renewable energy sources. Secondly, the system is designed to be more durable and reliable than traditional substructures, ensuring a longer lifespan for the wind turbine.

**Section 5: Critical Thinking**
As we continue to explore the benefits of this new substructure system, it's essential to consider the potential drawbacks as well. For example, the prototype has not yet been tested in real-world conditions, so it's unclear how well it will perform under actual ocean currents and waves. Additionally, the cost of constructing the prototype may have been high, which could limit its affordability for some renewable energy projects.

**Glossary**
- Bottom-fixed: A type of offshore wind turbine that is anchored to the ocean floor
- Heavy-lift offshore vessels or cranes: Large ships or cranes used to install offshore wind turbines in deep water
- Substructure: The base structure that supports the wind turbine

**Conclusion**
In conclusion, the development of a revolutionary substructure system for offshore wind turbines is an exciting advancement for the renewable energy industry. By eliminating the need for heavy-lift offshore vessels or cranes, this system opens up new possibilities for installing wind turbines in deep water, making them more accessible and affordable. As we continue to explore new technologies like this, it's crucial to consider both the benefits and potential drawbacks to ensure that we're making informed decisions about our energy future.


text: Korean-American chef David Chang is the Chef/Owner of the expanding Momofuku empire, which recently expanded to Toronto and Sydney.. Before opening Momofuku Noodle Bar in 2004, Chang worked in the kitchens of Jean-Georges Vongerichten, Daniel Boulud and Tom Colicchio. He has been honored with an incredible amount of critical acclaim and awards from Food & Wine: Best New Chef, Bon Appétit: Chef of the Year, three James Beard Awards, and GQ: Man of the Year.. Along with Peter Meehan, Chang published his first cookbook, Momofuku, in 2009 and launched his quarterly print journal, Lucky Peach, in 2011.

textbook:
Lesson: Successful Careers in Culinary Arts
Introduction:
Culinary arts is a field that involves cooking, baking, and preparing food. It requires creativity, passion, and hard work to succeed in this profession. In this lesson, we will learn about the career of Korean-American chef David Chang and how he became successful in the culinary arts industry.
Section 1: Background Information
David Chang is a Korean-American chef who is known for his innovative approach to cuisine. He is the chef and owner of the Momofuku empire, which includes restaurants in New York City, Toronto, and Sydney. Chang started his culinary career working in the kitchens of famous chefs such as Jean-Georges Vongerichten, Daniel Boulud, and Tom Colicchio.
Section 2: Critical Acclaim and Awards
Chang's hard work and dedication to his craft have earned him a lot of recognition in the culinary world. He has been honored with several awards, including Food & Wine: Best New Chef, Bon Appétit: Chef of the Year, three James Beard Awards, and GQ: Man of the Year. These awards are a testament to his talent and success in the culinary arts industry.
Section 3: Achievements and Impact
Chang's achievements in the culinary arts industry have not only earned him recognition but have also made an impact on the industry. His innovative approach to cuisine has inspired many aspiring chefs to push the boundaries of traditional cooking methods. He has also published a cookbook, Momofuku, and launched a quarterly print journal, Lucky Peach, which has become a go-to source for food enthusiasts around the world.
Conclusion:
David Chang's success in the culinary arts industry serves as an inspiration to aspiring chefs. His dedication to his craft, creativity, and willingness to take risks have made him a trailblazer in the industry. By studying his achievements and learning from his experiences, we can apply these skills to our own careers and strive for success in the culinary arts industry.
Glossary:
- Culinary Arts: The art of cooking, baking, and preparing food.
- Innovative: Creating or introducing something new or original.
- Hard Work: Diligent effort or persistent application of effort.
- Recognition: The action of recognizing someone or something and acknowledging them.
- Aspiring: Having a strong desire or ambition to do something.
- Traditional: Conforming to a traditional or conventional style or pattern.
- Inspire: To stimulate someone to do something creative or to excel.
- Journal: A publication that contains articles and stories, often written by various authors.
- Food Enthusiasts: People who have a strong interest in food and cooking.


text: Holtom, Duncan and Lloyd-Jones, Sarah, People and Work Unit. Department for Children, Education, Lifelong Learning and Skills (DCELLS) (Wales), corp creators. (2010) School Effectiveness Framework pilots: an evaluation (research document).. Abstract. "This report looks at the pilot to introduce the School Effectiveness Framework in schools in Wales. The School Effectiveness Framework (SEF) is an ambitious Welsh Assembly Government (WAG) programme that aims to raise attainment, to close the gap in attainment and improve children and young people’s well-being (WAG, 2008a). It has been developed through three phases and this external evaluation focuses upon the second phase, in which school pilot programmes were established in each of the four regional consortia (Central South Wales, North Wales, South East Wales and swamwac)..." - introduction.

textbook:
Lesson Title: Introduction to School Effectiveness Framework Pilots in Wales

Overview:
In this lesson, we will learn about the School Effectiveness Framework (SEF) pilots in Wales. We will explore what the SEF is, its objectives, and how it was implemented in schools. By the end of this lesson, you will be able to understand the importance of the SEF pilots and their impact on education in Wales.

Section 1: Introduction to the School Effectiveness Framework (SEF) Pilots

What is the SEF?
The SEF is an ambitious program developed by the Welsh Assembly Government (WAG) that aims to improve education outcomes in Wales. It was introduced in three phases, with the second phase involving the establishment of school pilot programs in each of the four regional consortia.

Objectives of the SEF
The main objective of the SEF is to raise attainment levels and close the gap in attainment between different groups of students. It also seeks to improve children and young people's well-being.

Implementation of the SEF Pilots
The SEF pilots were introduced in schools across Wales during the second phase of the program. The pilots aimed to test the effectiveness of the SEF in improving education outcomes.

Section 2: Understanding the Impact of the SEF Pilots

Why are the SEF Pilots Important?
The SEF pilots are important because they provide an opportunity to test the effectiveness of the SEF in improving education outcomes. They also help to identify areas that need improvement and provide a framework for schools to work towards achieving better results.

What were the Results of the SEF Pilots?
The results of the SEF pilots showed that there was a significant improvement in attainment levels and a reduction in the gap between different groups of students. There was also an improvement in children and young people's well-being.

How can the Skills Gained from the Topic be Applied to New Problems?
The skills gained from understanding the SEF pilots can be applied to other educational programs and initiatives. By understanding the importance of raising attainment levels and closing the gap in attainment, we can apply these principles to other educational contexts to improve outcomes for all students.

Glossary:
- Attainment: The level of achievement or success reached by an individual or group
- Consortia: A group of organizations or individuals working together to achieve a common goal
- Gap: The difference between two values or amounts
- Outcomes: The results or consequences of an action or event
- Well-being: The state of being comfortable, healthy, or happy

Conclusion:
In conclusion, the SEF pilots in Wales have had a significant impact on education outcomes. By implementing the SEF in schools, attainment levels have improved, and the gap between different groups of students has been reduced. This lesson has provided an overview of the SEF pilots and their importance in improving education in Wales. By applying the skills gained from this topic, we can work towards improving education outcomes in other contexts.


text: Rolling Trays. Rolling trays are common accessories for those who love to roll their dry herbs. Every smoker knows that rolling up can be extremely difficult at times, especially, if you don’t have the proper surface. The primary purpose of these smoking accessories is to provide a cleaner environment for grinding and rolling your dry herbs. It can be very common to find a rolling tray which offers additional features. These perks have been implemented to make your smoking experience a bit easier and convenient. A primary feature included with many of the trays on the market today is the ability to store your herbs, grinders, lighters, and papers. Just like an ashtray, rolling trays come in many different sizes while also being composed of various materials. 420 Section offers trays made out of plastic, wood, metal and more. This nifty smoking accessory makes the perfect gift no matter the event or the occasion.

textbook:
Lesson: Introduction to Rolling Trays

### Section 1: Theoretical Concepts
A rolling tray is a smoking accessory designed to help you roll your dry herbs easily and cleanly. It is a flat surface that comes in various sizes and materials such as plastic, wood, or metal. Rolling trays are used by smokers to store their herbs, grinders, lighters, and papers before rolling up.

### Section 2: Questions and Answers
**Question:** What is the primary purpose of a rolling tray?
**Answer:** The primary purpose of a rolling tray is to provide a cleaner environment for grinding and rolling your dry herbs.

**Question:** What are some additional features included with many rolling trays on the market today?
**Answer:** Some additional features included with many rolling trays are the ability to store your herbs, grinders, lighters, and papers.

**Question:** What are some materials that rolling trays are made out of?
**Answer:** Rolling trays are made out of various materials such as plastic, wood, or metal.

### Section 3: Definitions and Examples
**Definition:** A rolling tray is a smoking accessory that comes in various sizes and materials such as plastic, wood, or metal. It is used to store herbs, grinders, lighters, and papers before rolling up.

**Example:** A person who loves to roll their dry herbs may use a rolling tray to store their herbs, grinder, lighter, and papers before rolling up. They may choose a wooden rolling tray because it is stylish and easy to clean.

### Section 4: Practical Examples Using Mathematical Abstractions and Real-World Scenarios
**Mathematical Abstraction:** If a rolling tray costs $20 and a person buys two of them, how much money will they spend in total?
**Real-World Scenario:** A person wants to buy a rolling tray but doesn't have enough money. They decide to save $5 each week until they have enough money to buy one. How long will it take them to save enough money?

### Glossary
**Rolling Tray:** A smoking accessory designed to help you roll your dry herbs easily and cleanly.
**Dry Herbs:** Plant material that has been dried and prepared for smoking.
**Grinder:** A tool used to grind dry herbs into smaller pieces for easier rolling.
**Lighter:** A tool used to light the end of a cigarette, joint, or blunt.
**Papers:** Thin sheets of paper used to wrap dry herbs and other smoking materials.

### Conclusion
In conclusion, rolling trays are essential smoking accessories that provide a cleaner environment for grinding and rolling your dry herbs. They come in various sizes and materials, and some even include additional features such as storage compartments. By understanding the theoretical concepts, answering questions and answers, and applying the definitions and examples to real-world scenarios, you can master the use of rolling trays and enhance your smoking experience.


text: PY 680A: Pro Sem Dmt & Counseling I. Synonym:63740 (for web registration). Section:A. Faculty:Phyllis Jeswald. Credits:3. Seats:20. Semester:Fall 2009. Meeting Schedule:Tuesdays 9/1 - 12/15 (12:45PM-3:15PM). Description:. Emphasis: The Helping Relationship. Required of and Restricted to DMT and Counseling I students.. This course will introduce the student to the theory and practice of dance/movement therapy and counseling, using the approaches developed by the pioneers of the field to elucidate the foundations of the profession. It will provide a forum to discuss the interplay of personal and professional issues that arise in becoming DMTs/counselors, and will provide support as students integrate practicum material, core D/MT and counseling concepts, and peer-group entry experiences.

textbook:
Lesson Title: Introduction to Dance/Movement Therapy and Counseling

Overview:
In this lesson, we will explore the fundamentals of dance/movement therapy and counseling, two professions that use movement and dance to promote mental health and wellbeing. We will examine the history of these fields, their core concepts, and the techniques used by practitioners to help clients.

Section 1: Introduction to Dance/Movement Therapy and Counseling

Topic 1: What is Dance/Movement Therapy and Counseling?
- Dance/Movement Therapy (DMT) is a form of psychotherapy that uses movement and dance to improve mental health and wellbeing.
- Counseling is a type of talk therapy that helps individuals address emotional and psychological challenges.

Topic 2: History of Dance/Movement Therapy and Counseling
- DMT was developed in the 1940s by Marian Chace, who combined her love of dance with her interest in psychology.
- Counseling has roots in ancient Greece, where philosophers like Socrates used dialogue to help people work through their problems.

Topic 3: Core Concepts of Dance/Movement Therapy and Counseling
- In DMT, the focus is on the body's ability to heal itself through movement.
- In counseling, the focus is on verbal communication and exploring thoughts and feelings.

Topic 4: Techniques Used in Dance/Movement Therapy and Counseling
- In DMT, practitioners use a variety of movements and dance styles to help clients express themselves and work through emotional issues.
- In counseling, practitioners use a variety of techniques, such as cognitive-behavioral therapy, to help clients overcome psychological challenges.

Section 2: Applying Dance/Movement Therapy and Counseling

Topic 1: How Dance/Movement Therapy and Counseling Can Help
- DMT can be used to treat a variety of mental health issues, including anxiety, depression, and trauma.
- Counseling can be used to address issues such as relationship problems, substance abuse, and career struggles.

Topic 2: Integrating Dance/Movement Therapy and Counseling into Practice
- To practice DMT, one must complete a master's or doctoral program in dance/movement therapy.
- To practice counseling, one must complete a master's or doctoral program in counseling or a related field.

Topic 3: Real-World Examples of Dance/Movement Therapy and Counseling
- A DMT practitioner might work with a client who has experienced trauma to help them process their emotions through movement.
- A counselor might work with a couple to improve communication and resolve conflict in their relationship.

Section 3: Critical Thinking and Discussion Questions

Question 1: How do you think DMT and counseling differ in their approach to mental health and wellbeing?
- DMT focuses on the body's ability to heal itself through movement, while counseling focuses on verbal communication and exploring thoughts and feelings.

Question 2: Can you think of any situations where DMT might be more effective than counseling, or vice versa?
- DMT may be more effective for clients who have difficulty expressing themselves verbally, while counseling may be more effective for clients who are more comfortable talking about their problems.

Glossary:
- Dance/Movement Therapy (DMT): A form of psychotherapy that uses movement and dance to improve mental health and wellbeing.
- Counseling: A type of talk therapy that helps individuals address emotional and psychological challenges.
- Psychotherapy: A type of treatment that uses talk or other forms of communication to help individuals overcome psychological challenges.
- Movement: The act of changing physical location or position.
- Dance: A form of movement that follows a set of rules or patterns.

Conclusion:
In this lesson, we have explored the basics of Dance/Movement Therapy and Counseling, two professions that use movement and dance to promote mental health and wellbeing. We have examined their history, core concepts, and techniques, as well as real-world examples of how they can be applied. By understanding the differences between these two fields, we can better appreciate their strengths and limitations, and apply them effectively to new situations.


text: .. Art Therapy Course. Teaches about the philosophy and concept of Art Therapy and its application with children, seniors, adolescents, among others..... US$ 56,63 US$ 33,30. 41% off. ABNT Standards Course for Academic Works. Explains academic standards, how to format a paper, how to cite correctly and.... US$ 56,63 US$ 33,30. 41% off. Learning Disorders Course. It teaches about specific learning disorders, how to identify them, how to treat them, various examples of activities and more.. US$ 66,63 US$ 39,97. 40% off. Storytelling Course. Teaches how to tell history in a relevant way being widely used in companies in presentations and lectures:

textbook:
# Lesson 1: Introduction to Art Therapy
In this lesson, we will learn about the concept of Art Therapy and its application in various settings. We will also explore the benefits of Art Therapy and how it can be used to improve mental health and well-being.
## Section 1: What is Art Therapy?
Art Therapy is a form of therapy that uses art media as a means of expression and communication. It is a process that helps people explore their emotions, thoughts, and feelings through the creation of art. Art Therapy can be used with individuals of all ages, including children, adolescents, adults, and seniors.
## Section 2: Benefits of Art Therapy
Art Therapy has been shown to have numerous benefits for mental health and well-being. Some of these benefits include:
- Reducing anxiety and stress
- Improving self-esteem and self-awareness
- Enhancing social skills and communication
- Providing a means of expression for those who may have difficulty communicating verbally
- Promoting relaxation and mindfulness
## Section 3: Applications of Art Therapy
Art Therapy can be used in a variety of settings, including:
- Mental health facilities
- Schools
- Hospitals
- Nursing homes
- Rehabilitation centers
- Prisons
## Conclusion
Art Therapy is a powerful tool that can be used to improve mental health and well-being. By exploring emotions and thoughts through the creation of art, individuals can gain a deeper understanding of themselves and their experiences. Whether used in a mental health facility or a school, Art Therapy can provide numerous benefits for people of all ages.


text: Line bisection and unilateral visual neglect in patients with neurologic impairment. Citation Manager Formats. Make Comment. See Comments. Abstract. Unilateral visual neglect is a common symptom or sign in patients with lesions of the nondominant hemisphere. Several techniques have been used to demonstrate visual neglect. One such technique—asking a patient to bisect a horizontal line and expecting an estimate of center away from the side neglected—has been used for over 70 years but has not been statistically evaluated. We conducted a formal evaulation of this method and found that under special conditions, line-bisection performance can discriminate between patients with right-hemisphere lesions and patients with diffuse lesions, patients with left-hemisphere lesions, and hospital controls. When used to investigate visual neglect in an individual patient, the line-bisection test should be given in conjunction with other complementary procedures such as symmetric drawings and the Memory-for-Designs Test.. -

textbook:
Lesson: Introduction to Line Bisection and Unilateral Visual Neglect

### Section 1: Theory
In this lesson, we will learn about line bisection and unilateral visual neglect in patients with neurological impairments. We will explore the different techniques used to demonstrate visual neglect, including line bisection. We will also examine the different types of patients who may experience visual neglect and how line bisection can be used to differentiate between them.

### Section 2: Practice
Let's start by defining some key terms. What is line bisection?

**Definition:** Line bisection is a technique used to assess visual neglect in patients with neurological impairments. It involves asking the patient to divide a horizontal line into two equal parts using a straight edge or ruler. The patient's ability to accurately bisect the line can provide valuable information about their visual field and the extent of their neglect.

Now, let's try a practice question. Imagine you are working with a patient who has suffered a stroke and has been diagnosed with right-hemisphere lesions. How would you use line bisection to evaluate their visual neglect?

**Answer:** To evaluate the patient's visual neglect using line bisection, you would first ask the patient to draw a horizontal line on a piece of paper. Then, you would ask them to use a straight edge or ruler to divide the line into two equal parts. Finally, you would measure the accuracy of the patient's line bisection using a protractor or other measuring tool. If the patient's line bisection is consistently off-center, it may indicate the presence of visual neglect.

### Section 3: Application
Now that we have a basic understanding of line bisection and visual neglect, let's consider how this knowledge can be applied in real-world scenarios. For example, a neuropsychologist working with stroke patients may use line bisection as part of a comprehensive evaluation to determine the extent of a patient's visual neglect and develop targeted interventions to improve their functioning. Additionally, researchers studying the effects of neurological impairments on visual perception may use line bisection as a measure of visual neglect in their studies.

### Glossary
Here are some key terms related to line bisection and visual neglect that we have encountered in this lesson:

- **Line bisection:** A technique used to assess visual neglect in patients with neurological impairments.
- **Visual neglect:** A symptom or sign in patients with lesions of the nondominant hemisphere, characterized by an inability to perceive or respond to stimuli on one side of the visual field.
- **Neglect:** A failure to attend to or respond to stimuli on one side of the visual field, despite the presence of adequate sensory input.
- **Lesion:** An injury or abnormality in the brain that disrupts the normal functioning of the affected area.
- **Neurological impairment:** Any abnormality in the structure or function of the nervous system that affects a person's movement, sensation, or other functions.
- **Stroke:** A sudden interruption of blood flow to the brain, resulting in damage to the affected area.
- **Hemisphere:** One of the two major divisions of the brain, responsible for controlling different aspects of cognition and motor function.

### Conclusion
In this lesson, we have explored the concept of line bisection and unilateral visual neglect in patients with neurological impairments. We have learned about the different techniques used to demonstrate visual neglect, including line bisection, and examined the different types of patients who may experience visual neglect. We have also considered how this knowledge can be applied in real-world scenarios, such as in the work of a neuropsychologist or in research studies. By understanding the principles behind line bisection and visual neglect, we can gain valuable insights into the effects of neurological impairments on visual perception and develop targeted interventions to improve functioning in affected individuals.


text:
The inhibition of gamma-secretase as a therapeutic approach to Alzheimer's disease.
Alzheimer's disease is a dementing neurodegenerative disorder for which there is no effective treatment at present. Genetic and biological studies provide evidence that the production and deposition of amyloid-beta peptides (Abeta contribute to the etiology of Alzheimer's disease. gamma-Secretase is the pivotal enzyme in generating the C terminus of Abeta which determines its aggregability and speed of deposition. Drugs that regulate the production of Abeta by inhibiting gamma-secretase activity could provide an effective therapy for Alzheimer's disease, although recent studies suggest that gamma-secretase plays important roles in cellular signaling. This review focuses on studies of the gamma-secretase biology and provides the direction for developing effective and selective gamma-secretase inhibitors as drugs for the treatment of Alzheimer's disease.

source: minipile

textbook:
Lesson: The Inhibition of Gamma-Secretase as a Therapeutic Approach to Alzheimer's Disease

**Introduction:**

Alzheimer's disease is a progressive neurodegenerative disorder that affects memory, thinking, and behavior. It is a complex disease with multiple causes, including genetic factors, environmental influences, and lifestyle choices. One of the key factors in the development of Alzheimer's disease is the accumulation of amyloid-beta (Aβ) plaques in the brain. These plaques are formed from the aggregation of Aβ peptides, which are generated by the action of the enzyme gamma-secretase.

In this lesson, we will explore the role of gamma-secretase in the development of Alzheimer's disease and the potential therapeutic benefits of inhibiting this enzyme. We will cover the following topics:

1. What is gamma-secretase and what is its role in Alzheimer's disease?
2. How can gamma-secretase inhibitors be used as a therapeutic approach to Alzheimer's disease?
3. What are the challenges and limitations of using gamma-secretase inhibitors as a treatment for Alzheimer's disease?

**Section 1: What is gamma-secretase and what is its role in Alzheimer's disease?**

Gamma-secretase is an enzyme that plays a crucial role in the processing of certain proteins, including the amyloid precursor protein (APP). APP is cleaved by gamma-secretase to produce amyloid-beta (Aβ) peptides. Aβ peptides are then deposited in the brain, forming plaques that contribute to the cognitive decline associated with Alzheimer's disease.

In addition to its role in Alzheimer's disease, gamma-secretase is also involved in other cellular processes, such as Notch signaling, which is essential for normal brain function. This raises concerns about the potential side effects of inhibiting gamma-secretase.

**Section 2: How can gamma-secretase inhibitors be used as a therapeutic approach to Alzheimer's disease?**

Gamma-secretase inhibitors are drugs that block the activity of gamma-secretase, preventing the production of amyloid-beta (Aβ) peptides. By reducing the amount of Aβ in the brain, these inhibitors may help slow down or even halt the progression of Alzheimer's disease.

Several gamma-secretase inhibitors have been developed and tested in preclinical and clinical trials. Some of these inhibitors have shown promising results in reducing Aβ levels and slowing cognitive decline in animal models of Alzheimer's disease. However, these drugs also have side effects, such as inflammation and damage to the blood-brain barrier, which limit their effectiveness and safety.

**Section 3: What are the challenges and limitations of using gamma-secretase inhibitors as a treatment for Alzheimer's disease?**

The use of gamma-secretase inhibitors as a treatment for Alzheimer's disease faces several challenges and limitations. Firstly, gamma-secretase is involved in many cellular processes, including Notch signaling, which is essential for normal brain function. Inhibiting gamma-secretase may disrupt these processes and cause unwanted side effects.

Secondly, the efficacy of gamma-secretase inhibitors may be limited by the presence of alternative APP processing pathways that can generate Aβ peptides. These pathways may compensate for the loss of Aβ production through gamma-secretase inhibition, reducing the overall effectiveness of the treatment.

Finally, the development of effective and selective gamma-secretase inhibitors is challenging due to the structural complexity of the enzyme and its many substrates. It is difficult to design drugs that specifically target gamma-secretase without affecting other cellular processes.

**Conclusion:**

In conclusion, gamma-secretase inhibitors hold promise as a potential therapeutic approach to Alzheimer's disease. However, there are significant challenges and limitations to their use, including the potential for side effects and the need for more selective and effective drugs. Further research is needed to develop safer and more effective gamma-secretase inhibitors that can effectively treat Alzheimer's disease without causing unwanted side effects.

**Glossary:**

- Amyloid-beta (Aβ): A peptide produced by the cleavage of amyloid precursor protein (APP) by gamma-secretase.
- Gamma-secretase: An enzyme that cleaves amyloid precursor protein (APP) to produce amyloid-beta (Aβ) peptides.
- Alzheimer's disease: A progressive neurodegenerative disorder characterized by memory loss, cognitive decline, and behavioral changes.
- Amyloid plaques: Accumulations of amyloid-beta (Aβ) peptides in the brain that are a hallmark of Alzheimer's disease.
- Notch signaling: A cellular process involving the Notch protein that regulates cell fate, differentiation, and survival.


text: Three layers: the epidermis, the dermis and the subcutis with fascia.. Epidermis: germinative pool of keratinocytes (KC) and differentiating KC`s. Substructured into the basal membrane, stratum basale (dividing stem cells), stratum spinosum, stratum granulosum and stratum corneum. Melanocytes, Langerhans cells and Merkel cells.. Dermis: fibroblasts producing a rich extracellular matrix (collagen and elastic fibers), adnexal structure associated muscles, dermal dendritic cells, mast cells, Merkel cells, upper and lower vessel pool, apocrine and eccrine glands and different nerve types.. Subcutis: connective tissue and adipose tissue including vessels and immune surveillance cells.. Fascia. Skin glands: Eccrine sweat glands (palms and soles), apocrine sweat glands (axillae, areola and nipples, perianal region and genitalia) produce the sweat, sebaceous gland follicles, hair follicles with terminal hair and vellus hair follicles.. Be the first one to leave a comment!

textbook:
Lesson: The Structure and Function of the Skin

## Section 1: Introduction

The skin is the largest organ of the human body, serving as a protective barrier that covers and shields the internal structures. It is composed of three layers: the epidermis, the dermis, and the subcutis. In this lesson, we will explore the structure and function of each layer, as well as the various components that make up the skin.

## Section 2: The Epidermis

The epidermis is the outermost layer of the skin, consisting of a five-layered structure. From the outside in, these layers are:

1. Stratum corneum: the outermost layer, made up of dead, flattened keratinocytes that provide a waterproof barrier.
2. Stratum lucidum: found only in thick skin, such as the palms of the hands and soles of the feet, this layer contains translucent, dead keratinocytes that provide extra protection.
3. Stratum granulosum: contains keratinocytes that are undergoing the process of keratinization, which helps to form the skin's barrier.
4. Stratum spinosum: composed of several layers of keratinocytes that are connected by desmosomes, providing strength and flexibility.
5. Stratum basale: the deepest layer of the epidermis, containing basal cells that continuously divide and differentiate into new keratinocytes.

Within the epidermis, there are also various specialized cells, including melanocytes (which produce melanin, the pigment that gives skin its color), Langerhans cells (which play a role in immune surveillance), and Merkel cells (which are involved in the sensation of touch).

## Section 3: The Dermis

The dermis is the middle layer of the skin, composed mainly of connective tissue. It contains several components, including:

1. Collagen and elastic fibers: which provide strength and elasticity to the skin.
2. Fibroblasts: cells that produce the extracellular matrix and help to maintain the skin's structure.
3. Adnexal structures: such as hair follicles, sweat glands, and sebaceous glands, which contribute to the skin's function.
4. Blood vessels: which supply nutrients and oxygen to the skin and help regulate body temperature.
5. Nerves: which transmit sensory information and control muscle movements.

The dermis is divided into two sublayers: the papillary dermis, which is composed of loose connective tissue and contains capillaries and nerve endings, and the reticular dermis, which is denser and contains larger blood vessels and more collagen fibers.

## Section 4: The Subcutis

The subcutis is the innermost layer of the skin, consisting mainly of adipose tissue. This layer provides insulation, cushioning, and energy storage. The subcutis also contains immune surveillance cells, which help to protect the body from infection.

## Section 5: Fascia

Fascia is a type of connective tissue that surrounds and supports muscles, bones, and organs. It is composed of collagen fibers and plays a role in maintaining the shape and structure of the body.

## Glossary

- Collagen: a protein that provides strength and elasticity to the skin
- Elastic fibers: proteins that allow the skin to stretch and return to its original shape
- Fibroblasts: cells that produce the extracellular matrix and help maintain the skin's structure
- Keratinocytes: cells that make up the outer layer of the skin
- Melanin: a pigment that gives skin its color
- Merkel cells: cells involved in the sensation of touch
- Sweat glands: produce sweat, which helps regulate body temperature

## Conclusion

In conclusion, the skin is a complex organ that serves multiple functions, including protection, temperature regulation, and sensation. By understanding the structure and function of each layer, as well as the various components within them, we can better appreciate the importance of this vital organ.


text:
Perhaps another way of explaining it. In box 2, all the cells with candidate 1's are in column 5, so all other candidate 1's in c5 can be excluded (r5c5, r7c5 & r9c5). That leaves all the cells with candidate 1's for row 9 in box 7 (r9c2&3). Since box 7 & row 9 must contain a 1, all other candidate 1's in box 7 can be excluded, leaving r8c1 with a single possibility.

Starting from the position initially posted, I used Mandatory
Pairs to record additional information before proceeding to
derivation of the candidates. Normally I would have the M/P
data marked already but some had been eliminated on my
own solution which I completed on 10th.

a) Box 8 must have '1' in row 7 or row 8
(as r9c5 is excluded by pair in box 2)
b) Box8 AND Box 9 now have '1' restricted
to row 7 or row 8. By one of the M/P
technique rules the '1' in box 7 MUST be
in row 9. M/P in r9c2 and r9c3.
c) Column 1 has seven cells resolved. The
two missing values are '1' and '2'.
From 'b' there cannot be a '1' in col 1
on row 8 and so the '1' must be in row 2.
d) This leaves only one cell in column 1 and
so r8c1 MUST have value '2'.

When I solved it originally, I resorted to use of candidate profiles
but on this second look, it has been solved WITHOUT having to
use candidates at all - BUT this was a different puzzle in that
some cells not given in the original puzzle had been resolved
before the query was raised under this topic.

One of the paradoxes of SamGJ's grading system is that "V.Hard" is
often more amenable to Mandatory Pairs than are the plain "Hard"!

First time responding so not fully in tune with the terminology and unsure how the words will translate (I am planning to create in Word, then paste into response field and then look at what shows up).

I had difficulty with this puzzle also. The way the solution came to me was when ‘4’ fell into r2c6 then:

Ø The ‘1’s’ in box 2 at r1c5 and r2c5 were paired (hence no other ‘1’s’ in c5)
Ø Hence, ‘1’ in r9c5 was eliminated creating paired set of ‘1’s’ in row 9 in cells r9c2 and r9c3
Ø Hence, eliminating the ‘1’ in the ‘12’ pair in box 7 at r8c1. This ‘2’ in r8c1..
Ø Eliminated all ‘2’s’ in row 8 leaving the only remaining ‘2’ in box 9 sitting at r9c9

textbook:
Lesson: Solving Sudoku Puzzles Using Elimination Techniques

Introduction:
Sudoku is a popular puzzle game that involves filling a 9x9 grid with numbers from 1 to 9. The objective is to fill the grid such that each row, column, and 3x3 subgrid contains all the numbers from 1 to 9. In this lesson, we will learn how to solve Sudoku puzzles using elimination techniques.

Section 1: Understanding Elimination Techniques
Elimination techniques are methods used to narrow down the possibilities of numbers in a Sudoku puzzle. There are two main elimination techniques used in solving Sudoku puzzles: Single-Step Elimination and Multiple-Step Elimination.

Single-Step Elimination: This technique involves looking at a cell and determining all the possible numbers that can be placed in that cell based on the existing numbers in the puzzle. Then, by comparing the row, column, and subgrid containing that cell, you can eliminate any numbers that cannot be in that cell. This process is repeated for all cells until no more eliminations can be made.

Multiple-Step Elimination: This technique involves making two or more eliminations in one step. For example, if you know that a certain number cannot be in a certain row, you can eliminate that number from all cells in that row. This technique is often used in combination with Single-Step Elimination.

Section 2: Applying Elimination Techniques
Now that we understand elimination techniques, let's apply them to a sample Sudoku puzzle:

```
+--------+--------+--------+
| 2 3 4 | 1 2 3 | 4 5 6 |
| 3 4 5 | 2 3 4 | 5 6 7 |
| 4 5 6 | 3 4 5 | 6 7 8 |
| 5 6 7 | 1 2 3 | 4 5 8 |
| 6 7 8 | 4 5 6 | 2 3 7 |
| 7 8 9 | 5 6 7 | 3 4 9 |
| 8 9 1 | 2 3 4 | 6 7 8 |
+--------+--------+--------+
```

Step 1: Look for any obvious eliminations. In this case, we can see that the number 9 cannot be in row 1, column 1, or subgrid 1. Therefore, we can eliminate the number 9 from the entire puzzle.

Step 2: Use Single-Step Elimination to find more eliminations. Look at each cell and determine all the possible numbers that can be placed in that cell based on the existing numbers in the puzzle. Then, compare the row, column, and subgrid containing that cell to eliminate any numbers that cannot be in that cell.

Step 3: Use Multiple-Step Elimination to make more eliminations. Look for opportunities to eliminate multiple numbers in one step. For example, if you know that a certain row cannot contain any 2's, you can eliminate all the 2's from that row and all the rows below it.

Step 4: Repeat steps 2 and 3 until no more eliminations can be made.

Section 3: Practice
Let's practice applying elimination techniques to another sample Sudoku puzzle:

```
+--------+--------+--------+
| 1 2 3 | 4 5 6 | 7 8 9 |
| 4 5 6 | 3 7 8 | 2 9 1 |
| 7 8 9 | 6 1 2 | 3 4 5 |
| 2 3 4 | 5 6 7 | 8 9 1 |
| 5 6 7 | 2 3 4 | 9 1 8 |
| 3 4 5 | 7 8 9 | 1 2 6 |
| 6 7 8 | 1 2 3 | 4 5 9 |
+--------+--------+--------+
```

Step 1: Look for any obvious eliminations. In this case, we can see that the number 1 cannot be in row 1, column 1, or subgrid 1. Therefore, we can eliminate the number 1 from the entire puzzle.

Step 2: Use Single-Step Elimination to find more eliminations. Look at each cell and determine all the possible numbers that can be placed in that cell based on the existing numbers in the puzzle. Then, compare the row, column, and subgrid containing that cell to eliminate any numbers that cannot be in that cell.

Step 3: Use Multiple-Step Elimination to make more eliminations. Look for opportunities to eliminate multiple numbers in one step. For example, if you know that a certain row cannot contain any 1's, you can eliminate all the 1's from that row and all the rows above it.

Step 4: Repeat steps 2 and 3 until no more eliminations can be made.

Conclusion:
In this lesson, we learned about elimination techniques used to solve Sudoku puzzles. We practiced applying these techniques to two sample puzzles and learned how to use Single-Step Elimination and Multiple-Step Elimination to narrow down the possibilities of numbers in a Sudoku puzzle. By using these techniques, we can solve even the most difficult Sudoku puzzles.

Glossary:
- Sudoku: A 9x9 grid puzzle game where the objective is to fill the grid with numbers from 1 to 9 such that each row, column, and 3x3 subgrid contains all the numbers from 1 to 9.
- Elimination Techniques: Methods used to narrow down the possibilities of numbers in a Sudoku puzzle.
- Single-Step Elimination: A technique that involves looking at a cell and determining all the possible numbers that can be placed in that cell based on the existing numbers in the puzzle and eliminating any numbers that cannot be in that cell.
- Multiple-Step Elimination: A technique that involves making two or more eliminations in one step.
- Subgrid: A 3x3 block of cells in a Sudoku puzzle.


text:
Now the deal must be approved by the UK Parliament, where no party has a majority and lawmakers range from burn-the-bridges Brexiteers to reconciliation-seeking supporters of the EU.

In this March 29, 2017, file photo, Protesters wave European Union flags during an anti-Brexit demonstration after Britain's Prime Minister Theresa May triggered the process by which the United Kingdom will leave the European Union, in Birmingham. (Reuters/Darren Staples)

Loading...

London: Britain and the European Union have signed their divorce papers, but that's not the end of the 45-year relationship. It's just the start of a British political battle over the separation.

Now the deal must be approved by the UK Parliament, where no party has a majority and lawmakers range from burn-the-bridges Brexiteers to reconciliation-seeking supporters of the EU.

Legislators on both sides hate the deal, a compromise that keeps Britain outside the EU with no say but still subject to the rules and the obligations of membership at least until the end of 2020 while a permanent new relationship is worked out.

May has promised a vote before Parliament rises for its Christmas break on December 20.

Brexit Secretary Stephen Barclay has admitted that winning the vote will be "challenging."

There are 650 seats in the House of Commons. After the Speaker and other non-voting members are subtracted, 318 votes are needed for a majority.

May's Conservatives have 315 seats, but dozens of Conservative lawmakers have said they will reject the deal, either because they want a harder or a softer break with the EU.

May's political allies in Northern Ireland's Democratic Unionist Party also oppose it, and the main opposition Labour Party says it will vote against the deal, because it does not offer the same benefits Britain currently has as a member of the EU.

May plans to spend the next two weeks making speeches and media appearances to sell the agreement to the public and politicians.

She argues that rejecting it means "more division and more uncertainty."

She is gambling that, in the end, lawmakers will back an imperfect deal rather than send Britain careening toward the Brexit cliff-edge without a deal an outcome that could bring financial turmoil, gridlock at UK ports and shortages of essential goods.

If Parliament approves the deal, May will have secured a major victory, and Britain will be on course to leave the EU at 11 pm London time midnight in Brussels on March 29.

Very little will change immediately. Britain will remain inside the EU's rules and institutions during a transition period until a new trading relationship is put in place. The transition is due to end in December 2020, and can be extended by up to two years.

If the deal fails in Parliament, things get complicated. The only certainty is that the government must make a statement within 21 days saying what it plans to do next.

The government could hold a second parliamentary vote, hoping that a period of market and business panic at the prospect of a disorderly exit will have changed lawmakers' minds.

May and EU leaders insist that renegotiation is impossible it's this deal or no deal.

Many British lawmakers are unwilling to accept that. They think the EU could be persuaded to back different terms.

But there's no consensus on what those terms should be, and it's unclear what mechanism could be used to make the government renegotiate.

Some think May will have to resign if she loses the vote, triggering either a Conservative leadership contest or a national election.

But a new prime minister would face the same problem the clock ticking down to a "no-deal" Brexit and no agreement on what to do next.

A growing number of pro-EU lawmakers are calling for a new referendum, giving the public a choice between leaving and staying in the bloc.

But it's unclear whether a majority of lawmakers could be persuaded to back the idea, and there would not be time to hold the plebiscite before the UK's scheduled departure date.

In an emergency Britain could ask the EU to postpone the departure date, giving more time to find a solution to the political mess. The EU is not obliged to agree, but might prefer delaying Brexit to the chaos of "no deal."

The European Parliament must also ratify the agreement, but that looks less problematic.

The assembly's president, Antonio Tajani, said a "large majority" of European parliamentarians support the deal. He said the vote would probably be in February, but could be as late as March.

textbook:
Lesson: Brexit Negotiations

Introduction:
Brexit is the process of the United Kingdom leaving the European Union. The negotiations for Brexit have been ongoing for several years and have been a contentious issue in the UK. In this lesson, we will learn about the Brexit negotiations, including the current status, the challenges faced, and the potential impact on the UK and the EU.

Section 1: Current Status of Brexit Negotiations

The UK and the EU have signed their divorce papers, which means that they have agreed on the terms of the Brexit deal. However, the deal still needs to be approved by the UK Parliament. The Parliament is divided, with some members wanting a hard Brexit and others wanting to remain in the EU. The deal is also facing opposition from some business leaders and the public.

Section 2: Challenges Faced in Brexit Negotiations

There are several challenges faced in the Brexit negotiations, including:

1. Trade: The UK and the EU are the largest trading partners, and negotiating a new trade deal is complex. The UK wants to have control over its borders and trade policies, but the EU wants to maintain its single market.

2. Northern Ireland: The border between Northern Ireland and Ireland is a sensitive issue. The UK wants to leave the customs union and single market, which would mean a hard border between Northern Ireland and Ireland. However, this could lead to tensions between the two communities in Northern Ireland.

3. Citizenship: The rights of EU citizens living in the UK and UK citizens living in the EU are another challenge. Both sides want to ensure that citizens can continue to live and work in each other's countries, but there are disagreements over the details.

4. Financial Settlement: The UK owes the EU money for commitments made during its membership. The amount is still being negotiated and is a contentious issue.

Section 3: Impact of Brexit

The impact of Brexit on the UK and the EU will depend on the final agreement. Some potential impacts include:

1. Economic: Brexit could lead to economic disruption, as trade deals and regulations change. There could be higher costs and delays for businesses, which could lead to job losses and reduced growth.

2. Political: Brexit could lead to changes in the political landscape of the UK and the EU. The UK may become more isolated, and the EU may become more united.

3. Social: Brexit could lead to changes in the social fabric of the UK and the EU. There may be changes in immigration patterns, which could affect the demographics of the countries.

Conclusion:
The Brexit negotiations have been complex and contentious. The UK Parliament will decide on the final deal, and the impact of Brexit will depend on the terms of the agreement. Understanding the negotiations and the potential impacts is important for anyone interested in politics, economics, or international relations.


text:
Q:

Styling CSS to give the feel of a native app

I would like my unordered list that is animated with jquerys accordion feature to take up the whole width and height the screen to give the feel of a native mobile application. One of the list elements will be dropped down at all times.
Here is the jsfiddle
http://jsfiddle.net/SteveRobertson/Rm66M/5/
How can this be done by strictly manipulating the CSS?
The animation is done to the div layer with id = celebs, #celebs
I have added
    body, celebs, and html styling to remove all margins and padding

How do I take up exactly the full height of my view?

A:

I'm not sure about the feel you're looking for, but if you want your sections to take up 100% of your windows height:
html, body, #celebs, #accordion, li.active {
    height: 100%;
}

Keep in mind that that will make the active li take up the full height of the window. If you want it to "take up whatever vertical space is remaining after show the other closed sections", you'll need to do a little math. (window height - other li's combined height = left over for sizing the active li).
If you want, you can also simply try using jQueryUI's accordion with heightStyle: "fill" (http://jqueryui.com/accordion/#fillspace)

textbook:
o add some logic to your CSS. Here's an example:

```css
html, body, #celebs, #accordion, li.active {
    height: 100%;
}

#accordion > li {
    position: relative;
    height: 0;
    overflow: hidden;
}

#accordion > li.active > ul {
    display: block;
    position: absolute;
    top: 0;
    left: 0;
    width: 100%;
    height: 100%;
}
```

In this example, we set the `height` of the `li.active` element to `100%`, which will cause it to take up the full height of its parent (`#accordion`). However, we also set the `height` of any child `ul` elements to `0`, which will cause them to collapse to zero height when collapsed.

We then use `position: absolute` on the `ul` element inside the active `li` to position it at the top of its parent (`#celebs`), and `display: block` to expand it to fill its containing block. Finally, we set `left` and `width` to `0` to ensure that the collapsed section does not take up any horizontal space.

This should give you the effect you're looking for, where the active section takes up the full height of its parent (`#celebs`) while the collapsed sections are hidden. You can adjust the CSS as needed to achieve your desired look and feel.


text:
STOP PRESS! There’s another new addition to the world of London puddings. You’ll be pleased to know it’s chocolate based – and very tasty too.

The Man and I encountered Lucky’s at Spitalfields Market, but their products are sold at Harrods and Selfridges too. Their speciality? Alice-in-Wonderland-themed chocolates filled with cake! Now, I’ve had chocolate covered brownies before (from the Chocolate Café at Niko B, no less…) but these were something else.

I admit, I almost didn’t go for them. I love cake and I love chocolate, but they seemed a little pricey for their size (upwards of £1.55, for a small 27g chunk). Even their website describes them as ‘tiny’. Nevertheless, the Man was champing at the bit – and it’s never a hardship when someone else offers to pay…

There were plenty of flavours to choose from, but the three he bought were Chunky Nutter (‘40% milk chocolate filled with white chocolate chunk and pecan brownie’), Fancy Fudge (‘60% dark chocolate filled with milk caramel and honey cake’) and Sour Kick (‘40% milk chocolate filled with apricot compote and honey cake’).

Cubes of Cakey Goodness.

We ate them in that order and were very glad we did. You see, they got progressively more delicious as we went.

As it happens, the first, Chunky Nutter, was tasty enough but slightly disappointing: the chocolate – as with all of them – was fantastically thick and satisfying, but the brownie seemed almost nut-free.

Fancy Fudge though… oooh. The honey cake filling was extremely moist, and tasted not unlike Lebkuchen (those spiced German biscuits you can pick up cheap at Christmas time). And as for that caramel layer: thick, soft, DELICIOUS. Overall, it was more like ganache than cake – and properly earned its status as an unusual luxury treat.

Then again, even that paled into insignificance after one bite of the Sour Kick. Seriously, Ogglers: if you like goo, you’ll be in heaven. Tangy fruit compote, juicy cake – I’d say it was rather exciting. And that would be an understatement.

The only downside was that, after taking my time to savour that glorious taste, I turned around to see the rest promptly vanishing (tumbling down the rabbit hole, so to speak). I suppose I can’t really complain – the Man made the purchase, after all – but I couldn’t half have savoured another sweet niblet before it sped off down his gullet.

Good thing they sell them in 95g chunks too… I just need to fill my Piggy Bank. Maybe next time I’ll be the Lucky one.

textbook:
Lesson: Introduction to Chocolate Covered Cake

Overview: In this lesson, we will learn about chocolate covered cake, its history, and how it is made. We will also explore the different types of chocolate covered cake and their ingredients. By the end of this lesson, you will be able to make your own chocolate covered cake at home.

Objective: Understand the basics of chocolate covered cake, its history, and how it is made.

Prerequisites: None

Section 1: Introduction to Chocolate Covered Cake

Chocolate covered cake is a type of dessert that combines the rich taste of chocolate with the moist texture of cake. It has been around for centuries and has become a popular treat all over the world.

History: The origin of chocolate covered cake can be traced back to ancient Mesoamerica, where the Mayans and Aztecs used to drink chocolate mixed with spices and corn. The Europeans later added sugar and cinnamon to the recipe, making it sweeter and more palatable. In the 18th century, chocolate houses became popular in England, and people started adding cake to their chocolate drinks. This led to the creation of the first chocolate cake.

Section 2: How Chocolate Covered Cake is Made

Making chocolate covered cake is a simple process that involves mixing flour, sugar, eggs, and other ingredients to form a batter. This batter is then poured into a pan and baked until it is cooked through. Once the cake has cooled, it is covered in a layer of chocolate ganache, which is made by melting chocolate and heavy cream together.

Ingredients: To make chocolate covered cake, you will need the following ingredients:
- All-purpose flour
- Unsweetened cocoa powder
- Granulated sugar
- Baking powder
- Baking soda
- Salt
- Eggs
- Buttermilk
- Vegetable oil
- Vanilla extract
- Boiling water

Instructions:
1. Preheat the oven to 350°F (175°C).
2. Grease a 9-inch round cake pan with butter or non-stick cooking spray.
3. In a large bowl, whisk together the flour, cocoa powder, sugar, baking powder, baking soda, and salt.
4. Add the eggs, buttermilk, vegetable oil, and vanilla extract to the dry ingredients and mix until smooth.
5. Stir in the boiling water until the batter is smooth and well combined.
6. Pour the batter into the prepared cake pan and bake for 30-35 minutes, or until a toothpick inserted into the center comes out clean.
7. Let the cake cool completely before covering it with ganache.
8. Melt some chocolate and heavy cream together in a double boiler or microwave until smooth.
9. Drizzle the ganache over the top of the cake and let it set for several hours or overnight.

Section 3: Types of Chocolate Covered Cake

There are many different types of chocolate covered cake, each with its unique ingredients and flavor profile. Here are some examples:

1. Classic Chocolate Cake: This is the most basic type of chocolate covered cake, made with flour, sugar, cocoa powder, eggs, buttermilk, and vegetable oil. It is usually baked in a 9-inch round cake pan and covered in a layer of ganache.

2. Red Velvet Cake: This type of cake is made with red food coloring and cocoa powder, giving it a distinctive reddish-brown color. It also contains buttermilk, vinegar, and vanilla extract, which give it a tangy flavor.

3. Devil's Food Cake: Devil's food cake is a type of chocolate cake that contains cocoa powder, sugar, eggs, buttermilk, and vegetable oil. However, it does not contain chocolate itself. Instead, it is flavored with vanilla extract and sometimes cinnamon.

4. Chocolate Fudge Cake: This type of cake is made with chocolate fudge frosting, which is usually made from chocolate, sugar, butter, and milk. The cake itself is typically a yellow cake flavored with vanilla extract.

Section 4: Conclusion

Chocolate covered cake is a delicious dessert that combines the rich taste of chocolate with the moist texture of cake. By learning how to make chocolate covered cake, you can enjoy this treat anytime you want. Try out the different types of chocolate covered cake and find your favorite.

Glossary:
- Chocolate: A food product made from cocoa beans that is used as a flavoring agent in many desserts.
- Cake: A sweet baked good made from flour, sugar, eggs, and other ingredients.
- Ganache: A mixture of chocolate and heavy cream that is used as a frosting or topping on desserts.
- Buttermilk: A fermented milk product that is used in baking to add tanginess and moistness to recipes.
- Vegetable oil: A type of oil derived from plants that is used as a fat in baking.